| Name: | 雪莲提取物 saussurea lappa extract |
| CAS号 CAS Number: | 90106-55-1 |
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| ECHA EC 数 Number: | 290-278-1 |
类别 Category:cosmetic ingredient for skin conditioning
美国 US/欧盟 EU EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | | cosmetic ingredient for skin conditioning |
| 关键影响 IFRA Critical Effect: | | 皮肤致敏 Dermal sensitization |
| | 查看ifra标准 View the IFRA Standard |
| 推荐的雪莲草lappa根提取物的使用水平最高为 Recommendation for saussurea lappa root extract usage levels up to: | | | 禁止的 PROHIBITED: 不应用作香料成分。 Should not be used as a fragrance ingredient.
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| 推荐的雪莲草根提取物风味使用水平最高为 Recommendation for saussurea lappa root extract flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
| | 雪莲提取物 saussurea lappa extract |
| pubchem（sid） Pubchem (sid): | 135309294 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and 核心组件 core components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
同义词 Synonyms:
| | aucklandia aucklandia 肋根 costus root extract | | | 肋根 costus root extract | | | 闭鞘姜/云木香根的提取物 extract of the roots of the costus, 雪莲 saussurea lappa, 菊科 asteraceae | | | saussurea 肋根 costus root extract |
文章 Articles:
| 已发布 PubMed:用uplc / ms / ms方法测定从雪莲中分离出的倍半萜内酯的含量和细胞毒性。 UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa. |
| 已发布 PubMed:在uttarakhand 种植的雪莲雪莲根的挥发性成分 Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, 印度。 India. |
| 已发布 PubMed:兰（Saussurea lappa）根抗某些 类病原体的抗性评估 Evaluation of anti-resistant activity of Auklandia (Saussurea lappa) root against some human pathogens. |
| 已发布 PubMed:番木瓜根水提物改善异丙肾上腺素所致大鼠的氧化性心肌损伤。 Aqueous extract of Saussurea lappa root ameliorate oxidative myocardial injury induced by isoproterenol in rats. |
| 已发布 PubMed:圣玛琳娜 Santamarin, 从雪莲中分离出的倍半萜内酯 a sesquiterpene lactone isolated from Saussurea lappa, 通过在鼠巨噬细胞中表达血红素加氧酶-1来抑制lps诱导的炎症反应。 represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells. |
| 已发布 PubMed: 鉴别于马铃薯小ept变种中的药用植物提取物和木脂素的杀幼虫活性。 asiatica反对家蝇（musca domestica l。）。 |
| 已发布 PubMed:基质固相分散萃取结合hplc二极管阵列检测方法分析雪莲（Sussurea lappa c.b.clarke）根中的倍半萜烯内酯。 Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke. |
| 已发布 PubMed:脱水肋内酯可预防成骨细胞mc3t3-e1细胞中的线粒体功能障碍。 Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells. |
| 已发布 PubMed:一种新的倍半萜烯和其他来自雪莲草的成分。 A new sesquiterpene and other constituents from Saussurea lappa root. |
| 已发布 PubMed:雪莲提取物对d-半乳糖胺和脂多糖诱导的小鼠肝炎的抗肝毒性作用。 Antihepatotoxic activity of Saussurea lappa extract on D-galactosamine and lipopolysaccharide-induced hepatitis in mice. |
| 已发布 PubMed:皮雪莲根中脱氢肋内酯诱导du145 前列腺癌细胞的凋亡 Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa. |
| 已发布 PubMed:认证的雪莲 Authentication of Saussurea lappa, 濒危药物 an endangered medicinal material, 通过其dna和5s rrna测序。 by ITS DNA and 5S rRNA sequencing. |
| 已发布 PubMed:番木瓜根提取物乙醇对明串球菌吞噬活性的影响 Effects of Saussurea lappa roots extract in ethanol on leukocyte phagocytic activity, 淋巴细胞增殖和干扰素-γ（ifn-γ）。 lymphocyte proliferation and interferon-gamma (IFN-gamma). |
| 已发布 PubMed:在雪莲中存在胆碱能和钙拮抗剂成分可以解释其在便秘和痉挛中的用途。 Presence of cholinergic and calcium antagonist constituents in Saussurea lappa explains its use in constipation and spasm. |
| 已发布 PubMed:雪莲lappa诱导ags胃癌细胞的g2生长停滞和凋亡。 Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells. |
| 已发布 PubMed:在通过经lps刺激的原始264.7细胞中，apun和mapk活性的下调可以抑制木香酚抑制白介素1β的表达。 Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells. |
| 已发布 PubMed:雪莲的根具有细胞毒性倍半萜烯内酯。 Cytotoxic sesquiterpene lactones from the root of Saussurea lappa. |
| 已发布 PubMed:来自新鲜肋木根的胚芽。 Germacrenes from fresh costus roots. |
| 已发布 PubMed:木香内酯通过ros介导的线粒体通透性转变和细胞色素c释放诱导凋亡。 Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release. |
| 已发布 PubMed:抑制巨噬细胞系中草药制剂padma 28诱导的一氧化氮合成。 Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line. |
| 已发布 PubMed:雪莲根脱氢肋内酯和木香内酯对小鼠中枢橙花系统的影响。 Effect of dehydrocostus lactone and costunolide from Saussurea root on the central nervous system in mice. |
| 已发布 PubMed:多元醇对黑曲霉van teighem菊粉酶热失活的影响。 Effect of polyols on heat inactivation of Aspergillus niger van Teighem inulinase. |
| 已发布 PubMed:鼠耳草的活性化合物抑制 肝癌细胞中的乙型肝炎 表面抗原基因表达。 Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells. |
| 已发布 PubMed:雪莲胺 Saussureamines A, B, C, D, 和e and E, 中国雪莲基的新抗溃疡原则。 new anti-ulcer principles from Chinese Saussureae Radix. |
| 已发布 PubMed:车前子根油中的倍半萜类（雪莲laplap clarke） Sesquiterpenoids from costum root oil (Saussurea lappa Clarke) |
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