| 已发布 PubMed:黄连解毒汤汤口服后6种生物碱药理化学和综合药代动力学 Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of Huang-Lian-Jie-Du-Tang decoction. |
| 已发布 PubMed:黄连中棕榈碱对幽门螺杆菌和胃损伤的抑制作用 Inhibitory Activities of Palmatine from Coptis chinensis Against Helicobactor pylori and Gastric Damage. |
| 已发布 PubMed:小ber碱在糖尿病治疗中的抗氧化和抗炎活性。 Antioxidant and Anti-Inflammatory Activities of Berberine in the Treatment of Diabetes Mellitus. |
| 已发布 PubMed:药草相互作用对黄和黄连对大鼠根茎蒽醌生物利用度的影响 Involvement of herb-herb interactions in the influences of Radix Scutellaria and Coptis Chinensis on the bioavailability of the anthraquinones form Rhei Rhizoma in rats. |
| 已发布 PubMed:qrzslxf的干预作用 Intervention effects of QRZSLXF, 中草药食谱 a Chinese medicinal herb recipe, 溃疡性结肠炎大鼠模型中dor-β-逮捕 arrestin1-bcl2信号转导途径的研究 |
| 已发布 PubMed:常用药用植物提取物抗金黄熊果活性的比较。 A Comparison of the Anti-Staphylococcus aureus Activity of Extracts from Commonly Used Medicinal Plants. |
| 已发布 PubMed: 巴马汀 palmatine激活ahr并上调hepg2细胞中的cyp1a活性，但不上调 类肝细胞中的cyp1a活性。 |
| 已发布 PubMed:来自天然产物的非甾体抗炎药激活基因1（nag-1）调节剂作为抗癌药。 Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents. |
| 已发布 PubMed:掌状大黄和黄连。 Rheum palmatum L. and Coptis chinensis Franch., 对酵母诱导的发热大鼠具有解热作用，涉及对trpv1和trpm8表达的调节。 exert antipyretic effect on yeast-induced pyrexia rats involving regulation of TRPV1 and TRPM8 expression. |
| 已发布 PubMed:使用表面增强拉曼散射（sers）直接分析中药。 Direct analysis of traditional Chinese medicines using surface-enhanced raman scattering (SERS). |
| 已发布 PubMed:黄连根中的生物碱促进c2c12肌管中葡萄糖的摄取。 Alkaloids from Coptis chinensis root promote glucose uptake in C2C12 myotubes. |
| 已发布 PubMed:小ber碱代谢产物可诱导低密度脂蛋白受体上调，从而在 肝癌细胞中发挥降脂作用。 Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells. |
| 已发布 PubMed:精制的金芪降糖片可通过降低小鼠的胰岛素抵抗和改善β细胞功能来改善糖尿病。 A refined-JinQi-JiangTang tablet ameliorates prediabetes by reducing insulin resistance and improving beta cell function in mice. |
| 已发布 PubMed:小碱抗抑郁样作用机制可能与抑制有机阳离子转运蛋白2和3有关。 Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine. |
| 已发布 PubMed:黄连解毒汤及其组分对胶原性节螺藻大鼠的保护作用 Protective effects of Huang-Lian-Jie-Du-Tang and its component group on collagen-induced arthritis in rats. |
| 已发布 PubMed:通过使用拓扑受约束的肽底物来抑制基于聚集蛋白聚糖酶（adamts-4和adamts-5）和基质金属蛋白酶的类黄酮基药效团的分析。 An application of wavelet moments to the similarity analysis of three-dimensional fingerprint spectra obtained by high-performance liquid chromatography coupled with diode array detector. |
| 已发布 PubMed:微型RNA-21-3p MicroRNA-21-3p, 小碱诱导的mirna a berberine-induced miRNA, 直接下调 蛋氨酸腺苷基转移酶2a和2b并抑制肝癌细胞的生长。 directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth. |
| 已发布 PubMed:黄连水煎剂可预防小鼠红细胞的氧化损伤。 Water decoction of coptidis rhizoma prevents oxidative damage in erythrocytes of mice. |
| 已发布 PubMed:响应面法优化超声波辅助提取黄连生物活性生物碱化合物的工艺。 Optimization of ultrasonic-assisted extraction of bioactive alkaloid compounds from rhizoma coptidis (Coptis chinensis Franch.) using response surface methodology. |
| 已发布 PubMed:交泰丸通过糖尿病大鼠骨骼肌中的磷脂酰肌醇3-激酶途径增强胰岛素信号传导。 Jiaotai pill enhances insulin signaling through phosphatidylinositol 3-kinase pathway in skeletal muscle of diabetic rats. |
| 已发布 PubMed:黄连与黄的可比性对大鼠肝微粒体五种亚酶活性的影响 [Effect of comparability of Coptis chinensis and Scutellaria baicalensis on five sub-enzymatic activities of liver microsomes in rats]. |
| 已发布 PubMed:小ber碱对cyp1的抑制作用 Inhibition of CYP1 by berberine, 巴马汀 palmatine, 和麻疯草碱 and jatrorrhizine: 选择性 selectivity, 动力学表征 kinetic characterization, 和分子建模。 and molecular modeling. |
| 已发布 PubMed:黄连对lps致内毒素血症炎症的抑制作用。 Inhibitory effect of Coptis chinensis on inflammation in LPS-induced endotoxemia. |
| 已发布 PubMed: 通过增加ampk蛋白活性和上调谷氨酰胺4的表达来提高胶态球对D b db / D b db小鼠的抗糖尿病活性。 |
| 已发布 PubMed:小ber碱通过肝癌细胞的线粒体途径诱导凋亡。 Berberine induces apoptosis via the mitochondrial pathway in liver cancer cells. |
| 已发布 PubMed:黄连纤维根提取物对两种豆科植物的化感作用 [Allelopathic effects of extracts from fibrous roots of Coptis chinensis on two leguminous species]. |
| 已发布 PubMed:左金丸乙醇提取物的抗抑郁样作用 Antidepressant-like effect of ethanol extract from Zuojin Pill, 含有两种黄连和毛uc子草药 containing two herbal drugs of Rhizoma Coptidis and Fructus Evodiae, 通过调节小鼠中的单胺能橙花递质系统来解释这一现象。 is explained by modulating the monoaminergic neurotransmitter system in mice. |
| 已发布 PubMed:盐酸麻风树碱可抑制c8161转移性黑素瘤细胞的增殖和新血管形成。 Jatrorrhizine hydrochloride inhibits the proliferation and neovascularization of C8161 metastatic melanoma cells. |
| 已发布 PubMed:黄连和黄连水提物对 致大鼠皮肤损伤的影响。 The effect of RHIZOMA COPTIDIS and COPTIS CHINENSIS aqueous extract on radiation-induced skin injury in a rat model. |
| 已发布 PubMed:乌鸡丸对 肠道菌群不同配伍作用的黄连生物碱代谢研究 [Study on metabolism of Coptis chinensis alkaloids from different compatibility of Wuji Wan in human intestinal flora]. |
| 已发布 PubMed:小ber碱对高糖和胰岛素诱导的心肌肥大中pparα/ no活化的影响。 Effect of Berberine on PPAR α /NO Activation in High Glucose- and Insulin-Induced Cardiomyocyte Hypertrophy. |
| 已发布 PubMed:中西医结合治疗62例免疫抑制治疗失败的再生障碍性再生障碍性贫血的临床观察 [Clinical observation of treating 62 patients with severe aplastic anemia failing in immunosuppressive therapy by integrative medicine]. |
| 已发布 PubMed:黄连化学成分 [Chemical constituents from Coptis chinensis]. |
| 已发布 PubMed:（1）h nmr光谱法对朱砂安神丸与朱砂比较的急性肝毒性和肾毒性进行代谢谱分析。 A metabolic profiling analysis of the acute hepatotoxicity and nephrotoxicity of Zhusha Anshen Wan compared with cinnabar in rats using (1)H NMR spectroscopy. |
| 已发布 PubMed:基于外观定量物理特性和内部质量评价的黄连分类研究 [Classification study of Coptis chinensis based on quantitative physical property characteristics of appearance and internal quality evaluation]. |
| 已发布 PubMed: 传统加工的黄连中生物碱uplc-qtof / ms分析。 |
| 已发布 PubMed:cyp450 1a2和多种ugt1a亚型负责 肝微粒体中的麻风树碱代谢。 CYP450 1A2 and multiple UGT1A isoforms are responsible for jatrorrhizine metabolism in human liver microsomes. |
| 已发布 PubMed:黄连多糖对stz诱导的糖尿病小鼠高脂饮食的抗糖尿病作用。 Anti-diabetic effect of Coptis Chinensis polysaccharide in high-fat diet with STZ-induced diabetic mice. |
| 已发布 PubMed: 小nt碱抗脂肪形成活性不是由wnt /β-连环蛋白 β-catenin途径介导的。 |
| 已发布 PubMed:大鼠有机阳离子转运蛋白2参与麻风树碱肾脏吸收。 Involvement of rat organic cation transporter 2 in the renal uptake of jatrorrhizine. |
| 已发布 PubMed:哥伦巴胺抑制细胞毒性低的转移性 瘤u2os细胞的增殖和新血管形成。 Columbamine suppresses the proliferation and neovascularization of metastatic osteosarcoma U2OS cells with low cytotoxicity. |
| 已发布 PubMed:质子核磁共振光谱法对黄连的品质评价和物种分化 Quality evaluation and species differentiation of Rhizoma coptidis by using proton nuclear magnetic resonance spectroscopy. |
| 已发布 PubMed:一种中药配方的抗糖尿病作用。 Anti-diabetic effect of a traditional Chinese medicine formula. |
| 已发布 PubMed:黄连素介导的高脂饮食喂养的大鼠肥胖和胰岛素抵抗的预防过程中肠道菌群的结构变化。 Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats. |
| 已发布 PubMed:黄连的同工酶和胁迫指数对uv-b 的响应 [Response of isozyme and stress indexes of Coptis chinensis to UV-B radiation]. |
| 已发布 PubMed:黄连的非生物碱化学成分 [Non-alkaloid chemical constituents from Coptis chinensis]. |
| 已发布 PubMed:高效液相色谱-电化学检测法测定大鼠血浆中的四种黄连生物碱 Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection. |
| 已发布 PubMed:动态聚类法建立黄连幼苗分类标准 [Establishment of seedling classification criteria of Coptis chinensis by dynamic clustering method]. |
| 已发布 PubMed:使用固定化的g蛋白偶联受体来筛选具有多个目标的具有生物活性的中药化合物。 Using immobilized G-protein coupled receptors to screen bioactive traditional Chinese medicine compounds with multiple targets. |
| 已发布 PubMed:黄连花序提取物对紫外线b诱导的光毒性的保护作用 Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, hplc-ms分析其化学成分。 and HPLC-MS analysis of its chemical composition. |
| 已发布 PubMed:中草药配方ibs-20的抗炎活性 Anti-Inflammatory Activities of a Chinese Herbal Formula IBS-20 In Vitro and In Vivo. |
| 已发布 PubMed:小ber碱改善β-淀粉样蛋白病理 Berberine ameliorates β-amyloid pathology, 橙花胶质病 gliosis, 认知的 cognitive 减损 impairment in an Alzheimer's 疾病 disease 转基因 transgenic 老鼠 mouse 模型 model. |
| 已发布 PubMed:增强紫外线 对黄连的代谢和小ber碱含量的影响 [Effect of enhanced UV-B radiation on metabolism and berberine content of Coptis chinensis]. |
| 已发布 PubMed:原位单次灌流大鼠肠道模型对黄连生物碱肠道吸收的研究 [Studies on intestinal absorption of alkaloids in Coptis chinensis by in situ single-pass perfused rat intestinal model]. |
| 已发布 PubMed:麻疯树碱药代动力学和代谢 Pharmacokinetics and metabolism of jatrorrhizine, 胃动力药物候选者。 a gastric prokinetic drug candidate. |
| 已发布 PubMed:使用1h nmr光谱和主成分分析对不同物种的黄连进行代谢鉴别。 Metabolic discrimination of rhizoma coptidis from different species using 1H NMR spectroscopy and principal component analysis. |
| 已发布 PubMed:利他嗪对大鼠肠梗阻术后胃肠道运输的影响 Effect of jatrorrhizine on delayed gastrointestinal transit in rat postoperative ileus. |
| 已发布 PubMed:黄连对常氧和慢性间歇性低氧缺氧大鼠离体胸主动脉血管收缩活性的影响 [Eeffects of Coptis Chinensis on vasoconstrictive activity of isolated thoracic aorta of normoxic and chronic intermittent hypobaric hypoxic rats]. |
| 已发布 PubMed:[针对肿瘤的天然苄基异喹啉生物碱筛选]。 [Screen for natural benzylisoquinoline alkaloids against tumor]. |
| 已发布 PubMed:洪雅县黄连有效成分和生物量的动态积累 [Dynamic accumulation of effective components and biomass of Coptis chinensis in Hongya county]. |
| 已发布 PubMed:黄连解毒汤及其拆方对血清前脂肪细胞增殖和分化的影响 [Effects of huanglian jiedu decoction and its disassembled recipes containing serums on the proliferation and differentiation of preadipocytes]. |
| 已发布 PubMed: 黄连和吴茱总 total总生物碱胃内漂浮两室渗透泵片体外制备及溶出度试验研究。 |
| 已发布 PubMed:[基于著名地区药物和生物测定的中药质量控制模式研究-工作参考]。 [Investigation on pattern of quality control for Chinese materia medica based on famous-region drug and bioassay--the work reference]. |
| 已发布 PubMed:天然产物在糖尿病治疗中的作用机理。 Mechanism of action of natural products used in the treatment of diabetes mellitus. |
| 已发布 PubMed:不同类型和产地黄连净净光合速率的研究 [Study on the net photosynthesis rate of Coptis chinensis from different types and production places]. |
| 已发布 PubMed:[基于刀-地草药和生物测定-黄连生物测定的中药质量控制模式和方法的研究]。 [Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis]. |
| 已发布 PubMed:发表在《中华医学杂志》上的中药和其他天然产物研究的十年审核（2000-2009）。 A ten-year audit of traditional Chinese medicine and other natural product research published in the Chinese Medical Journal (2000-2009). |
| 已发布 PubMed:中药中新型孕烷x受体激活剂的鉴定 Identification of novel pregnane X receptor activators from traditional Chinese medicines. |
| 已发布 PubMed:黄连花序提取物的体外和体内抗氧化性能。 In vitro and in vivo antioxidant properties of extracts from Coptis chinensis inflorescence. |
| 已发布 PubMed:黄连提取物对肠易激综合征大鼠的镇痛作用。 Analgesic effect of Coptis chinensis rhizomes (Coptidis Rhizoma) extract on rat model of irritable bowel syndrome. |
| 已发布 PubMed: 顶空固相微萃取与gc×gc-tofms结合用于分析黄连根茎中的挥发性化合物。 |
| 已发布 PubMed:将永久性遗传资源添加到分子生态资源数据库中2010年10月1日至2010年11月30日。 Permanent genetic resources added to Molecular Ecology Resources Database 1 October 2010-30 November 2010. |
| 已发布 PubMed:黄连提取物中的herg通道抑制剂。 HERG channel inhibitors in extracts of Coptidis rhizoma. |
| 已发布 PubMed:左金丸及其生物碱成分对激活蛋白1的抑制作用 Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, 核因子-κb nuclear factor-κB, 和hepg2细胞中的细胞转化。 and cellular transformation in HepG2 cells. |
| 已发布 PubMed:通过免疫调节和抑制氧化损伤，对黄连和黄柏糖苷具有抗紫外线 的作用。 Anti-ultraviolet radiation effects of Coptis chinensis and Phellodendron amurense glycans by immunomodulating and inhibiting oxidative injury. |
| 已发布 PubMed:小ber碱可通过抑制肝糖异生而改善糖尿病大鼠的葡萄糖代谢。 Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. |
| 已发布 PubMed:量热法在各种黄连抗菌活性评价中的应用 Applications of microcalorimetry in the antibacterial activity evaluation of various Rhizoma coptidis. |
| 已发布 PubMed:2致大鼠发热模型的代谢组学研究 Metabolomic study of a rat fever model induced with 2,4-二硝基苯酚和黄连粗制药物的治疗作用。 4-dinitrophenol and the therapeutic effects of a crude drug derived from Coptis chinensis. |
| 已发布 PubMed:含新中药配方的黄连对2型糖尿病大鼠的抗糖尿病作用。 Anti-diabetic effects of a Coptis chinensis containing new traditional Chinese medicine formula in type 2 diabetic rats. |
| 已发布 PubMed:黄连对鳞状细胞癌细胞信号网络的影响 The effect of coptis chinensis on the signaling network in the squamous carcinoma cells. |
| 已发布 PubMed: rp-hplc RP-hplc HPLC法同时测定不同地区黄连中的6种生物碱 |
| 已发布 PubMed:小ber碱心血管和代谢作用。 Cardiovascular and metabolic effects of Berberine. |
| 已发布 PubMed:黄连对乙酰苯肼诱导的小鼠红细胞氧化性溶血的作用及其机制 [Effect and its mechanism of Coptis chinensis on oxidative hemolysis of erythrocytes in mice induced by acetylphenylhydrazine]. |
| 已发布 PubMed:铜绿微囊藻的氧化损伤和抗氧化反应暴露于从金丝线分离的化感黄连素中。 Oxidative damage and antioxidant responses in Microcystis aeruginosa exposed to the allelochemical berberine isolated from golden thread. |
| 已发布 PubMed:中草药提取物（sk0506）可作为代谢综合征的潜在治疗药物。 Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome. |
| 已发布 PubMed:黄连和小ber碱对脂多糖刺激大鼠肠道损伤的预防作用。 Preventive effect of Coptis chinensis and berberine on intestinal injury in rats challenged with lipopolysaccharides. |
| 已发布 PubMed:[代谢 [Metabolism, 黄连总生物碱在大鼠体内的转化和分布 transformation and distribution of Coptis chinensis total alkaloids in rat]. |
| 已发布 PubMed:巴马汀通过抑制成骨细胞中核因子-κb配体表达的受体激活剂来减弱破骨细胞的分化和功能 Palmatine attenuates osteoclast differentiation and function through inhibition of receptor activator of nuclear factor-κb ligand expression in osteoblast cells. |
| 已发布 PubMed:传统泰国草药疗法对口疮的抗菌和抗氧化活性。 Antimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers. |
| 已发布 PubMed:天然产物在发现治疗橙花退行性疾病的新药物中的作用ii The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's 疾病 disease. |
| 已发布 PubMed:拟南芥g蛋白γ亚基3（agg3）的组成型或种子特异性过表达导致种子和油的产量增加，以及山茶的抗逆性提高。 Comparative analysis of the anti-inflammatory activity of Huang-lian extracts in lipopolysaccharide-stimulated RAW264.7 murine macrophage-like cells using oligonucleotide microarrays. |
| 已发布 PubMed:黄连和吴茱vo水提物对dhh致结肠癌前病变的影响 [Effects of Coptis chinensis and Evodia rutaecarpa water extract on DMH-induced precancerous lesion of colon]. |
| 已发布 PubMed:联香处方自微乳化给药系统研究 [Study on self-microemulsifying drug delivery system of LianXiang prescription]. |
| 已发布 PubMed:棕榈碱作为西尼罗河 抑制剂的鉴定。 Identification of palmatine as an inhibitor of West Nile virus. |
| 已发布 PubMed:小ber碱抗动脉粥样硬化机制的研究进展。 Advance of studies on anti-atherosclerosis mechanism of berberine. |
| 已发布 PubMed:小檗碱诱导 小檗碱 Berberine-诱发的 诱导 induced 激活 activation of 5'-adenosine 一磷酸活化 monophosphate-活性 activated 蛋白 protein 激酶 kinase 葡萄糖 glucose 运输 transport in 鼠 rat 骨骼的 skeletal 肌肉 肌肉 muscles. |
| 已发布 PubMed:某些植物化学物质的抗血管生成作用。 Antiangogenic effect of selected phytochemicals. |
| 已发布 PubMed:金丝线和小tis碱对铜绿微囊藻的抑制作用 Inhibitory effects of golden thread (Coptis chinensis) and berberine on Microcystis aeruginosa. |
| 已发布 PubMed:黄连组合的肠黏膜免疫调节活性比较根茎和吴茱bent。硫酸葡聚糖钠致小鼠溃疡性结肠炎 Comparison of the enteric mucosal immunomodulatory activity of combinations of Coptis chinensis Franch. Rhizomes and Evodia rutaecarpa (Juss.) Benth. Fruits in mice with dextran sulphate sodium-induced ulcerative colitis. |
| 已发布 PubMed:数字图像识别技术在二维指纹分析中的应用 The application of digital image recognition to the analysis of two-dimensional fingerprints. |
| 已发布 PubMed:调查 Investigation of the 差异 differences between the "冷 Cold" "热 Hot" 性质 nature of Coptis chinensis 特许经营 Franch its its 处理 processed 材料 材料 materials 基于 based on animal's 温度 tempe鼠 rature 向性 tropism. |
| 已发布 PubMed: 巴马汀 Palmatine可减轻d-半乳糖胺/脂多糖诱导的暴发性肝衰竭。 |
| 已发布 PubMed:生物碱小ber碱可通过诱导细胞周期停滞来抑制抗多香果的mcf-7和mda-mb-231乳腺癌细胞系的生长。 The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest. |
| 已发布 PubMed:黄连通过非甾体抗炎药激活的基因激活来抑制肝癌细胞的生长。 Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation. |
| 已发布 PubMed:黄连生物碱含量的显着差异 Significant differences in alkaloid content of Coptis chinensis (Huanglian), 来自其相关的美国物种。 from its related American species. |
| 已发布 PubMed:黄连对大鼠黄口服液中类黄酮药代动力学的影响 Influence of coptis Chinensis on pharmacokinetics of flavonoids after oral administration of radix Scutellariae in rats. |
| 已发布 PubMed:小ber碱对k562细胞分化和凋亡的影响 [Effect of berberine on the differentiation and apoptosis of K562 cell line]. |
| 已发布 PubMed:黄连不同部位水提物自身中毒研究 [Study on the autointoxication of aquatic extracts from different parts of Coptis chinensis]. |
| 已发布 PubMed:黄连和黄连总碱可减轻铝诱导的大鼠橙花退行性疾病模型的脑损伤。 Berberine and total base from rhizoma coptis chinensis attenuate brain injury in an aluminum-induced rat model of neurodegenerative disease. |
| 已发布 PubMed:降糖药及其作用机理。 Hypoglycemic herbs and their action mechanisms. |
| 已发布 PubMed: 1天竺葵中间提取物内酯玫瑰天竺葵（德之馨）花concentrole玫瑰天竺葵（德之馨）流 flowerpone玫瑰天竺葵（德之馨）allplant essential＆reg; org。玫瑰天竺葵p（德之馨） |
| 已发布 PubMed:添加剂对小鼠黄连总生物碱吸收及药代动力学的影响 [Effect of additives on absorption of Coptis chinensis total alkaloids and pharmacokinetics in mice]. |
| 已发布 PubMed:黄连中异喹啉生物碱羟自由基清除活性。 Hydroxyl radical scavenging activities of isoquinoline alkaloids isolated from Coptis chinensis. |
| 已发布 PubMed:中药黄连和吴茱e的协同作用在体内抑制s180肿瘤。 In vivo inhibition of S180 tumors by the synergistic effect of the Chinese medicinal herbs Coptis chinensis and Evodia rutaecarpa. |
| 已发布 PubMed:1h nmr快速简便地测定黄连中的原小ber碱生物碱及其在商业处方质量控制中的应用。 A rapid and simple determination of protoberberine alkaloids in Rhizoma Coptidis by 1H NMR and its application for quality control of commercial prescriptions. |
| 已发布 PubMed:hplc结合二极管阵列检测同时测定两种著名中药中的11种活性成分，以进行质量控制。 Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. |
| 已发布 PubMed:黄连提取物抑制u937细胞生长并诱导其凋亡。 Growth inhibition and induction of apoptosis in U937 cells by Coptis chinensis extract. |
| 已发布 PubMed:左金丸的体内抗癌活性及其对肉瘤180小鼠移植瘤标志物的影响 [Anti-cancer activity of Zuojinwan in vivo and influence to tumor markers in mice transplanted with sarcoma 180]. |
| 已发布 PubMed:小ber碱抗动脉粥样硬化机制研究进展。 [Advance on study in anti-atherosclerosis mechanism of berberine]. |
| 已发布 PubMed:[缓释肥料对产量的影响 [Effects of slow release-fertilizers on yield, 黄连的营养成分和品质 nutrient contents and quality of Coptis chinensis]. |
| 已发布 PubMed:耶尔森氏菌对小碱微阵列表达谱分析。 Microarray expression profiling of Yersinia pestis in response to berberine. |
| 已发布 PubMed:黄连生物碱对醛糖还原酶的抑制活性 Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase. |
| 已发布 PubMed:泻心汤及其成分不同组合中蒽醌的药代动力学 Pharmacokinetics of anthraquinones in Xiexin decoction and in different combinations of its constituent herbs. |
| 已发布 PubMed:泻心汤中蒽醌的药代动力学及其组成草药的不同组合。 Anthraquinone pharmacokinetics in Xiexin decoction and the different combinations of its constituent herbs. |
| 已发布 PubMed:小ber碱抑制血小板衍生的生长因子诱导的生长和迁移，部分通过血管平滑肌细胞中的ampk依赖性途径抑制。 Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells. |
| 已发布 PubMed:中草药黄连野生与栽培种群的遗传变异hinensis（毛茛/铁线莲）。 Genetic variation among wild and cultivated populations of the Chinese medicinal plant Coptis chinensis (Ranunculaceae). |
| 已发布 PubMed:加速溶剂萃取结合光电二极管阵列的超高效液相色谱分析和串联质谱检测技术对黄连中的生物碱进行分析 Analysis of alkaloids in Coptis chinensis Franch by accelerated solvent extraction combined with ultra performance liquid chromatographic analysis with photodiode array and tandem mass spectrometry detections. |
| 已发布 PubMed:激活血液循环和解毒中药某些有效成分对载脂蛋白基因敲除小鼠血脂和动脉粥样硬化斑块炎症反应的影响 [Effects of some active ingredients of Chinese drugs for activating blood circulation and detoxicating on blood lipids and atherosclerotic plaque inflammatory reaction in ApoE-gene knockout mice]. |
| 已发布 PubMed:[黄连对贵港地区葡萄糖-6-磷酸脱氢酶（g6pd）缺陷性黄疸的调查 [Investigation of Coptis chinensis on jaundice of glucose-6-phosphate dehydrogenase (G6PD) deficient neonates from Guigang, 广西]。 Guangxi province]. |
| 已发布 PubMed:黄连总生物碱对幽门螺杆菌诱导的大鼠胃部损伤的保护作用及其机制 [Protective effects and its mechanisms of total alkaloids from rhizoma Coptis chinensis on Helicobacter pylori LPS induced gastric lesion in rats]. |
| 已发布 PubMed:微量量热法测定黄连中的小ber碱生物碱抑菌性能 Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimetry. |
| 已发布 PubMed:是一种常见的食用菌。它是担子菌属，属于“ 囊菌”属。牡蛎蘑菇多见于中国食品。由于其营养丰富 Inhibitory effects of Zoagumhwan water extract and berberine on angiotensin II-induced monocyte chemoattractant protein (MCP)-1 expression and monocyte adhesion to endothelial cells. |
| 已发布 PubMed:不同栽培体系下黄连的质量评价 [Quality assessment for Coptis chinensis with different cultivating system]. |
| 已发布 PubMed:固定化dna固定相的亲和色谱用于中药的生物指纹分析。 Affinity chromatography with immobilized DNA stationary phase for biological fingerprinting analysis of traditional Chinese medicines. |
| 已发布 PubMed:黄柏和黄连的中草药制剂（rah13）在炎症动物模型中的抗炎作用。 Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation. |
| 已发布 PubMed: 基于ISSR ISSR分析的黄连种质遗传多样性 |
| 已发布 PubMed:吸收和共振瑞利散射光谱研究[hgx4] 2-与小ber碱相互作用及其分析应用。 Interaction of [HgX4]2- with berberine by absorption and resonance Rayleigh-scattering spectra and their analytical applications. |
| 已发布 PubMed:黄连花序开花的降血糖和降胆固醇作用。 Hypoglycemic and hypocholesterolemic effects of Coptis chinensis franch inflorescence. |
| 已发布 PubMed:天然植物提取物对黄萎病菌的抑制作用 [Inhibitory effects of natural plant extracts on Verticillium albo-atrum]. |
| 已发布 PubMed:生态种植黄连的指纹红外光谱分析与表征 [Analysis and characterization of fingerprint infrared spectra for ecology-planted Coptis chinensis]. |
| 已发布 PubMed:hplc-uv / ms定性定量测定黄连解毒汤的主要成分 [Qualitative and quantitative determination of the main components of huanglianjiedu decoction by HPLC-UV/MS]. |
| 已发布 PubMed:液相色谱/质谱法进行生物指纹分析，以评估天然产物中多种化合物的dna结构选择性。 Biological fingerprinting analysis by liquid chromatography/mass spectrometry for evaluation of DNA structural selectivity of multiple compounds in natural products. |
| 已发布 PubMed:牛皮癣治疗中药对培养的hacat细胞的抗增殖特性的评价 Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells. |
| 已发布 PubMed:三黄泻心汤有效成分的含量条件 [The content condition of effective composition in Sanhuang Xiexin decoction]. |
| 已发布 PubMed:[gc-ms分析yl2000汤中的挥发性成分]。 [Analysis of the volatile components of YL2000 decoction by GC-MS]. |
| 已发布 PubMed:小ber碱对细胞周期蛋白b1的下调和wee1的上调可促进白血病细胞进入细胞周期的g2 / m期。 Down-regulation of cyclin B1 and up-regulation of Wee1 by berberine promotes entry of leukemia cells into the G2/M-phase of the cell cycle. |
| 已发布 PubMed:黄连总生物碱对大鼠醇性胃损伤的保护作用 [Protective effects of total alkaloids from rhizoma Coptis chinensis on alcohol-induced gastric lesion in rats]. |
| 已发布 PubMed:超临界流体萃取法从黄连根中提取小ber碱 Extraction of berberine from rhizome of Coptis chinensis Franch using supercritical fluid extraction. |
| 已发布 PubMed:小ber碱抑制mek / erk依赖的egr-1信号通路，并抑制体外机械损伤后血管平滑肌细胞的再生。 Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury. |
| 已发布 PubMed:小碱单独和与氨苄青霉素或奥沙西林联用对耐甲氧西林金黄熊果的抗菌活性。 Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. |
| 已发布 PubMed:黄连生长过程中可溶性糖和氨基酸动态变化 [Dynamic change of soluble saccharides and amino acids during the growing period of Coptis chinensis]. |
| 已发布 PubMed:[黄连的种群特征。安徽省灯盏花及其危害机制] [Population characteristics of Coptis chinensis var. brevisepala in Anhui Province and its endangering mechanism]. |
| 已发布 PubMed:几种中国金丝线土壤养分特性的初步研究 [Preliminary studies on the nutrient characters of different kinds of Chinese goldthread soil]. |
| 已发布 PubMed:黄连总生物碱对实验性胃溃疡的研究 [Study of total alkaloids from Rhizoma Coptis Chinensis on experimental gastric ulcers]. |
| 已发布 PubMed:葛根勤连汤不同成分对家兔实验性志贺菌病的影响 [Effects of different compositions of Gegenqinlian decoction on experimental shigellosis in rabbits]. |
| 已发布 PubMed:小碱通过hepg2细胞中的核因子-κB信号通路抑制乙醛诱导的白介素-1β和肿瘤坏死因子-α的产生。 Acetaldehyde-induced interleukin-1beta and tumor necrosis factor-alpha production is inhibited by berberine through nuclear factor-kappaB signaling pathway in HepG2 cells. |
| 已发布 PubMed:中国黄连质量评价 [Quality assessment of Coptis chinensis in China]. |
| 已发布 PubMed:微透析/ hplc的针对dna的中药生物指纹图谱分析筛选和分析生物活性化合物。 Screening and analysis of bioactive compounds with biofingerprinting chromatogram analysis of traditional Chinese medicines targeting DNA by microdialysis/HPLC. |
| 已发布 PubMed:离子对中药黄连中牛血清白蛋白与氯化小ber碱相互作用的影响 Effect of metal ions on the interaction between bovine serum albumin and berberine chloride extracted from a traditional Chinese Herb coptis chinensis franch. |
| 已发布 PubMed: 使用氧化的碳纳米管作为基质，通过maldi-tof ms分析小分子。 |
| 已发布 PubMed:黄连的研究进展 [Research development of Coptis chinensis]. |
| 已发布 PubMed:植物药物控制物质的建立及黄连指纹图谱的建立 [Establishment of the control substance of plant drug and fingerprints of Coptis chinensis]. |
| 已发布 PubMed:丽川黄连中小ber碱含量分析 [Analysis of contents of berberine in Coptis chinensis of Lichuan]. |
| 已发布 PubMed:[黄连不同部位的分析与评价 [Analysis and assessment of Coptis chinensis for different parts, ages, 高度和高度的傅里叶变换红外光谱] and heights using Fourier transform infrared spectroscopy]. |
| 已发布 PubMed:棚内黄连种子的育苗和精细栽培技术 [Technique of storing Coptis chinensis seeds in damp sand under shed and fine cultivation of seedling]. |
| 已发布 PubMed:生态技术种植黄连的质量评价 [Quality assessment for Coptis chinensis planted with ecological techniques]. |
| 已发布 PubMed:[在木材中栽培黄连并与玉米共同栽培的生态技术]。 [Ecological technique of cultivating Coptis chinensis in woods and co-cultivating it with maize]. |
| 已发布 PubMed:黄连生态栽培研究的应用前景 [Application and prospect on the researches of ecological cultivation of Coptis chinensis]. |
| 已发布 PubMed:葛根秦连及其复方抗退热作用的实验研究。 [Experimental study on anti-pyretic effect of gegen qin lian decoction and its compounds]. |
| 已发布 PubMed:小ber碱肝胆排泄。 Hepatobiliary excretion of berberine. |
| 已发布 PubMed:中草药提取物的血管生成和抗血管生成活性。 Angiogenesis and anti-angiogenesis activity of Chinese medicinal herbal extracts. |
| 已发布 PubMed:异喹啉生物碱对细菌表面蛋白锚定转肽酶分选酶的抑制作用 Inhibition of the bacterial surface protein anchoring transpeptidase sortase by isoquinoline alkaloids. |
| 已发布 PubMed:黄连和 提取物及其主要成分（小ber碱）的细胞毒性作用 Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, 黄连 coptisine和苦瓜素 icariin）对肝癌和白血病细胞的生长。 |
| 已发布 PubMed:cdna芯片检测黄连复方对 鼻咽癌细胞株cne1移植瘤组织基因表达的影响 [Effect of Coptis Chinensis compound on the gene expression in transplanted tumor tissue in nasopharyngeal carcinoma cell line of CNE1 by cDNA microarray]. |
| 已发布 PubMed: [小瘦 thin碱成分的原位薄层色谱-傅立叶变换表面增强拉曼光谱研究]。 |
| 已发布 PubMed:高效毛细管电泳法测定小ber碱含量 High-performance capillary electrophoresis for determining the contents of berberine, 葛根勤连汤中的麻疯树碱和巴马汀。 jatrorrhizine and palmatine in Gegenqinlian decoction. |
| 已发布 PubMed:与黄连配伍后吴茱vo中药材中乙二胺和芸香碱含量测定 [Determination of evodiamine and rutaecarpine in Evodia rutaecarpa (Juss.) Benth after compatibility with Coptis chinensis Franch]. |
| 已发布 PubMed: [测定黄连中的生物碱。和黄柏amurense amurense卢布。毛细管电泳在白头翁汤中煎煮] |
| 已发布 PubMed:东方草药提取物的抗粉刺作用 Anti-acne effects of Oriental herb extracts: 选择抗 药物的新颖筛选方法。 a novel screening method to select anti-acne agents. |
| 已发布 PubMed:小ber碱对大鼠压力超负荷所致心脏肥大的消退作用 Effect of berberine on regression of pressure-overload induced cardiac hypertrophy in rats. |
| 已发布 PubMed:黄连中配伍后肉桂中肉桂酸测定 [Determination of cinnamic acid in Cinnamomum cassia presl after compatibility in Coptis chinensis Franch]. |
| 已发布 PubMed:药用植物提取物对克氏锥虫生长的抑制作用。 Inhibition of Trypanosoma cruzi growth by medical plant extracts. |
| 已发布 PubMed:极谱法测定药用植物中存在h（2）o（2）的小ber碱。 Polarographic determination of berberine in the presence of H(2)O(2) in medicinal plants. |
| 已发布 PubMed:抗炎植物提取物的抗氧化活性。 Antioxidant activity of anti-inflammatory plant extracts. |
| 已发布 PubMed:中草药对原发性致龋菌体外抑菌活性的实验研究 [Experimental study of bacteriostatic activity of Chinese herbal medicines on primary cariogenic bacteria in vitro]. |
| 已发布 PubMed:氮对黄连根茎中小ber碱生长和含量的影响 [Effect of different nitrogen concentrations on the growth and contents of berberine in rhizome of Coptis chinensis Franch]. |
| 已发布 PubMed:黄连和小ber碱对大鼠实验性葡萄糖6-磷酸脱氢酶缺乏症红细胞渗透性脆弱性的影响 [Influence of huanglian and berberine on the erythrocytic osmotic fragilitas of experimental glucose-6-phosphate dehydrogenase deficiency in rats]. |
| 已发布 PubMed:黄连与甘草合用对大鼠实验性葡萄糖6-磷酸脱氢酶缺乏症的红细胞渗透性脆弱性的影响 [Influence of huanglian used in combination with huangqin and gancao on the erythrocytic osmotic fragilitas of experimental glucose-6-phosphate dehydrogenase deficiency in rats]. |
| 已发布 PubMed:一些用于皮肤病的亚洲药用植物的局部抗炎活性。 Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. |
| 已发布 PubMed:黄连根中的单胺氧化酶抑制剂。 Monoamine oxidase inhibitors from rhizoma of Coptis chinensis. |
| 已发布 PubMed:增强认知能力的中草药对东pol碱所致大鼠健忘症的改善作用。 The ameliorating effects of the cognitive-enhancing Chinese herbs on scopolamine-induced amnesia in rats. |
| 已发布 PubMed:小ber碱。 Berberine. |
| 已发布 PubMed:精选草药的抗氧化和自由基清除活性。 Antioxidative and free radical scavenging activities of selected medicinal herbs. |
| 已发布 PubMed:小ber碱在 和鼠肝癌细胞中上调多药耐药转运蛋白的表达。 Up-regulation of multidrug resistance transporter expression by berberine in human and murine hepatoma cells. |
| 已发布 PubMed:和制备型高速逆流色谱法分离黄连中生物碱应用 Application of analytical and preparative high-speed counter-current chromatography for separation of alkaloids from Coptis chinensis Franch. |
| 已发布 PubMed:[黄连种子的生理生化变化。在分层和aba治疗的效果]。 [Physiological and biochemical changes of seeds of Coptis chinensis Franch. in stratification and the effect of ABA treatment]. |
| 已发布 PubMed:[氮的影响 [Effect of nitrogen, 磷和钾对黄连根茎生长及其黄连素含量的影响] phosphorus and potassium on the growth of rhizome of Coptis chinensis Franch and its contents of berberine]. |
| 已发布 PubMed:黄连细胞培养物中小ber碱分离与鉴定 Isolation and identification of berberine from cell cultures of Coptis chinensis. |
| 已发布 PubMed: 胚囊胚对中药的体外反应 In vitro response of Blastocystis hominis against traditional Chinese medicine. |
| 已发布 PubMed:[r质粒消除黄连对e的作用的实验研究。大肠杆菌]。 [Experimental study of R plasmid eliminating action of Coptis chinensis on E. coli]. |
| 已发布 PubMed:地质背景系统对四川原药的限制作用 [Restricting effects of geologic background system on genuine crude drugs in Sichuan]. |
| 已发布 PubMed:超声波提取对小ber碱提取率的影响 [Effect of ultrasonic extraction on extraction rate of berberine]. |
| 已发布 PubMed:从黄连根茎中分离的dna拓扑异构酶i和ii抑制剂。 Inhibitors of DNA topoisomerase I and II isolated from the Coptis rhizomes. |
| 已发布 PubMed:三黄合剂抑制血小板聚集的临床和实验研究 [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. |
| 已发布 PubMed:东方草药对脂多糖激活的大鼠巨噬细胞对il-8诱导的抑制作用。 Inhibitory effects of Oriental herbal medicines on IL-8 induction in lipopolysaccharide-activated rat macrophages. |
| 已发布 PubMed:黄连生长土壤的研究 [Studies on the soils for growth of Coptis chinensis Franch]. |
| 已发布 PubMed:流式细胞术分析小ber碱对 肝癌hepg2细胞糖皮质激素受体表达的影响。 Flowcytometric analysis of the effect of berberine on the expression of glucocorticoid receptors in human hepatoma HepG2 cells. |
| 已发布 PubMed:中草药对上消化道的吸收能力 [Absorptive capacity of upper gastrointestinal tract with Chinese herbal medicine]. |
| 已发布 PubMed:[清胃黄连丸的质量标准]。 [Quality standards for qingwei huanglian pills]. |
| 已发布 PubMed:小碱置换白蛋白中的胆红素。 Displacement of bilirubin from albumin by berberine. |
| 已发布 PubMed:高效液相色谱-荧光光度法测定生物样品中的小ber碱 [Determination of berberine in biological specimen by high performance TLC and fluoro-densitometric method]. |
| 已发布 PubMed:幽门螺杆菌与慢性萎缩性胃炎发病机制的关系及其防治研究 [Relation between Helicobacter pylori and pathogenesis of chronic atrophic gastritis and the research of its prevention and treatment]. |
| 已发布 PubMed:黄连对大鼠脂质过氧化和抗氧化酶活性的影响 [The effect of Coptis chinensis on lipid peroxidation and antioxidases activity in rats]. |
| 已发布 PubMed:中草药局部烧伤的临床和实验研究 [Clinical and experimental study of burns treated locally with Chinese herbs]. |
| 已发布 PubMed:反相高效液相色谱法测定黄连中药中的盐酸小ber碱 [Determination of berberine hydrochloride in traditional Chinese medicines containing Coptis chinensis Franch by reversed phase high performance liquid chromatography]. |
| 已发布 PubMed:流动注射分析法测定中成药中小ber碱型生物碱小ber碱电化学检测器 [Berberine-electrochemical detector for the determination of berberine-type alkaloids in various Chinese patent medicines by flow injection analysis]. |
| 已发布 PubMed:中国黄连植物中5种生物碱定量测定 [Quantitative determination of 5 alkaloids in plants of Coptis from China]. |
| 已发布 PubMed:黄连和小ber碱降血糖作用研究 [Studies on the hypoglycemic effect of Coptis chinensis and berberine]. |
| 已发布 PubMed:黄连菌丝繁殖的调查。 [Survey on the agamic propagation of Coptis chinensis]. |
| 已发布 PubMed:[黄连素描]。 [A sketch of the Coptis Chinensis]. |
| 已发布 PubMed:植物生长调节剂对黄连的影响 [Effect of plant growth regulator on Coptis chinensis]. |
| 已发布 PubMed:在不同海平面上种植黄连的经验 [Experience on the cultivation of Coptis chinensis at different sea-level]. |
| 已发布 PubMed:[关于黄连生物碱研究。变种狮王（v）]。 [ON ALKALOIDS FROM COPTIS CHINENSIS FRANCH. VAR. SHIHCHUENSIS WANG. (V)]. |
| 已发布 PubMed:[关于黄连生物碱研究。变种omeiensis chen。 （iv）]。 [ON ALKALOIDS FROM COPTIS CHINENSIS FRANCH. VAR. OMEIENSIS CHEN. (IV)]. |
