已发布 PubMed: 戈米菌素 gomisin a降低了小鼠腹膜巨噬细胞中lps诱导的inos和cox-2表达以及rip2 /nf-κb的激活。 |
已发布 PubMed:五味子乙素b通过抑制肌球蛋白轻链磷酸化来抑制tgfβ1诱导的应激纤维形成。 Schisandrin B suppresses TGFβ1-induced stress fiber formation by inhibiting myosin light chain phosphorylation. |
已发布 PubMed:五味子对木聚糖的肽聚糖辅助跨膜转运独特地改变了 类hepg2细胞模型的药代动力学和药效学机制。 Schisandra chinensis peptidoglycan-assisted transmembrane transport of lignans uniquely altered the pharmacokinetic and pharmacodynamic mechanisms in human HepG2 cell model. |
已发布 PubMed:五味子乙素b对心肌梗死小鼠心脏功能的有益作用。 Beneficial effects of schisandrin B on the cardiac function in mice model of myocardial infarction. |
已发布 PubMed:分子伴侣hsp72和橙花肽y作为植物提取物适应原活性的特征标记的评价 Evaluation of molecular chaperons Hsp72 and neuropeptide Y as characteristic markers of adaptogenic activity of plant extracts. |
已发布 PubMed:hplc-dad-ms结合化学计量学对五味子进行综合化学分析。 Comprehensive chemical analysis of Schisandra chinensis by HPLC-DAD-MS combined with chemometrics. |
已发布 PubMed:通过超高效液相色谱-质谱联用对五味子木脂素的吸收成分和代谢产物进行分析和鉴定。 Profiling and identification of the absorbed constituents and metabolites of schisandra lignans by ultra-performance liquid chromatography coupled to mass spectrometry. |
已发布 PubMed:脂多糖刺激的原始264.7巨噬细胞中的五味子果实提取物的水提取物对促炎性介质的下调。 Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells. |
已发布 PubMed:柱分级分离和超临界反溶剂沉淀法纯化五味子果实中木脂素 Purification of lignans from Schisandra chinensis fruit by using column fractionation and supercritical antisolvent precipitation. |
已发布 PubMed:saengmaeksan通过抑制rip-2 / caspase-1激活来抑制炎症介质。 Saengmaeksan inhibits inflammatory mediators by suppressing RIP-2/caspase-1 activation. |
已发布 PubMed:cxcr2对从五味子果实中分离的天然化合物α-异-异丁烯醇的免疫调节活性的作用。 Role of CXCR2 on the immune modulating activity of α-iso-cubebenol a natural compound isolated from the Schisandra chinensis fruit. |
已发布 PubMed:五味子的富含木脂素的提取物对淀粉样β诱导的小鼠皮层和海马区认知障碍和橙花毒性的影响。 The effects of lignan-riched extract of Shisandra chinensis on amyloid-β-induced cognitive impairment and neurotoxicity in the cortex and hippocampus of mouse. |
已发布 PubMed:五味子果实中花色苷的含量和颜色稳定性 Content and color stability of anthocyanins isolated from Schisandra chinensis fruit. |
已发布 PubMed: 戈米菌素 gomisin a通过信号转导子和转录激活因子介导的视网膜母细胞瘤蛋白磷酸化增强了肿瘤坏死因子-α诱导的g1细胞周期停滞。 |
已发布 PubMed: 草药五味子(五味子)中的戈米菌素 gomisin n通过c /ebpβ和nf-κb抑制大鼠肝细胞中的诱导型一氧化氮合酶基因。 |
已发布 PubMed:α-异丁烯醇的治疗作用 Therapeutic effects of α-iso-cubebenol, 从五味子中分离出来的天然化合物中国水果 a natural compound isolated from the Schisandra chinensis fruit, 对抗败血症。 against sepsis. |
已发布 PubMed:五味子中四种木脂素的单组分多组分定量分析同时定量分析 [Simultaneous quantitative analysis of four lignanoids in Schisandra chinensis by quantitative analysis of multi-components by single marker]. |
已发布 PubMed:α-异方苯 α-Iso-cubebene, 从五味子果实中分离的天然化合物 a natural compound isolated from Schisandra chinensis fruit, 对多菌血症有治疗作用。 has therapeutic benefit against polymicrobial sepsis. |
已发布 PubMed:五味子果实木脂素含量与抗氧化活性的化学计量关系 [Correlation of lignans content and antioxidant activities of Schisandra chinensis fruits by using stoichiometry method]. |
已发布 PubMed:从五味子的果实中分离出的脱氧五味子素改善了aβ12诱导的小鼠记忆障碍。 Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aβ₁₋₄₂-induced memory impairment in mice. |
已发布 PubMed:五味子乙素b在体外和体内对环孢素a诱导的肾毒性的保护作用。 Protective effect of schisandrin B against cyclosporine A-induced nephrotoxicity in vitro and in vivo. |
已发布 PubMed:细胞色素p-450催化活性氧的产生介导了h9c2心肌细胞中(-)五味子素b诱导的谷胱甘肽和热休克反应。 Cytochrome P-450-catalyzed reactive oxygen species production mediates the (-)schisandrin B-induced glutathione and heat shock responses in H9c2 cardiomyocytes. |
已发布 PubMed:五味子醋的化学成分研究 [Study on the chemical constituents of vinegar Schisandra chinensis]. |
已发布 PubMed:五味子提取物在小鼠体内的药代动力学和组织分布 [Pharmacokinetics and tissue distribution of Schisandra chinensis extract in mice]. |
已发布 PubMed:h(2)o(2)的影响 Effects of H(2)O(2), 百草枯 paraquat, 活性氧系统研究乙烯利和乙烯利对五味子草药品质的影响 and ethephon on herbal drug quality of Schiandra chinensis based on reactive oxygen species system. |
已发布 PubMed:大孔树脂对五味子果实提取物中脱氧五味子素和γ-五味子素的富集纯化。 Enrichment and purification of deoxyschizandrin and γ-schizandrin from the extract of Schisandra chinensis fruit by macroporous resins. |
已发布 PubMed:五味子果实提取物可减轻链脲佐菌素诱发的糖尿病性肾病小鼠模型中的蛋白尿并保护足细胞完整性。 Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy. |
已发布 PubMed:五味子和五味子果实中活性成分的均相离子液体微萃取。 Homogeneous ionic liquid microextraction of the active constituents from fruits of Schisandra chinensis and Schisandra sphenanthera. |
已发布 PubMed:一种来自五味子保尔的果实的免疫刺激性多糖(scp-iia)。 An immunostimulatory polysaccharide (SCP-IIa) from the fruit of Schisandra chinensis (Turcz.) Baill. |
已发布 PubMed:五味子浆果的精油的化学成分和抗氧化活性 Chemical composition and antioxidant activity of essential oil from berries of Schisandra chinensis (Turcz.) Baill. |
已发布 PubMed: 参 Panax ginseng, 红景天和五味子。 Rhodiola rosea and Schisandra chinensis. |
已发布 PubMed:离子液体的微波辅助提取五味子果实中的香精油和联苯环辛烯木脂素。 Ionic liquid-based microwave-assisted extraction of essential oil and biphenyl cyclooctene lignans from Schisandra chinensis Baill fruits. |
已发布 PubMed:提取物对五味子胞中海绵体平滑肌(csm)收缩力和ca2 +稳态的影响 Effects of Schisandra chinensis extract on the contractility of corpus cavernosal smooth muscle (CSM) and Ca2+ homeostasis in CSM cells. |
已发布 PubMed:五味子中的木脂素体外培养。 Lignans in Schisandra chinensis in vitro cultures. |
已发布 PubMed:接种了裂殖子表面蛋白1 c末端加上新型佐剂的小鼠中,与针对血液阶段疟疾的保护性免疫相关的细胞因子和抗体亚类。 Comprehensive quality evaluation of Fructus Schisandrae using electrospray ionization ion trap multiple-stage tandem mass spectrometry coupled with chemical pattern recognition techniques. |
已发布 PubMed:五味子α-异方苯酚通过pi3k / akt和nrf2信号传导诱导血红素加氧酶-1表达,并在牙龈卟啉单胞菌脂多糖刺激的巨噬细胞中具有抗炎活性。 Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages. |
已发布 PubMed:栽培地区不同类型干五味子(五味子)的挥发物和香气活性成分的组成 The compositions of volatiles and aroma-active compounds in dried omija fruits (Schisandra chinensis Baillon) according to the cultivation areas. |
已发布 PubMed:五味子素b在体内和体外对汞诱导的肾脏损害的不同作用。 Different role of Schisandrin B on mercury-induced renal damage in vivo and in vitro. |
已发布 PubMed:中药中新型孕烷x受体激活剂的鉴定 Identification of novel pregnane X receptor activators from traditional Chinese medicines. |
已发布 PubMed:五味子苷b对有或没有非诺贝特影响的小鼠的血清/肝甘油三酸酯和总胆固醇水平的有效动力学。 Effective kinetics of schisandrin B on serum/hepatic triglyceride and total cholesterol levels in mice with and without the influence of fenofibrate. |
已发布 PubMed:木酚素成分在五味子果实提取物对阴茎勃起的作用中的作用。 The role of the lignan constituents in the effect of Schisandra chinensis fruit extract on penile erection. |
已发布 PubMed:在体外和体内研究中,五味子的富含木脂素的级分可通过ppar-γ途径提高胰岛素敏感性。 The lignan-rich fractions of Fructus Schisandrae improve insulin sensitivity via the PPAR-γ pathways in in vitro and in vivo studies. |
已发布 PubMed: [关于卡杜拉 kadsura kaempf.ex juss属的正确中文名称的争论]。 |
已发布 PubMed:离子液体超声提取五味子果实中联苯环辛烯木脂素的研究 Study on ionic liquid-based ultrasonic-assisted extraction of biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill. |
已发布 PubMed:五味子果实的色谱指纹图谱研究 [Research on chromatographic fingerprint of fruits of Schisandra chinesis]. |
已发布 PubMed:五味子素可增强原代培养海马橙花元的树突生长和突触形成。 Schisandrin enhances dendrite outgrowth and synaptogenesis in primary cultured hippocampal neurons. |
已发布 PubMed: 戈米菌素 gomisin n通过抑制nf-κb和egfr生存途径来增强tnf-α诱导的凋亡。 |
已发布 PubMed:五味子果实中的降冰片萜和木脂素。 Nortriterpenoids and lignans from the fruit of Schisandra chinensis. |
已发布 PubMed:在线tlc-dart-ms对五味子中主要二苯并环辛烷木脂素的定量分析。 Quantitative analysis of major dibenzocyclooctane lignans in Schisandrae fructus by online TLC-DART-MS. |
已发布 PubMed:大鼠原位单次灌流对五味子保鲜汤有效成分的肠道吸收作用 [Intestinal absorption of the effective components of Schisandra chinensis Baill by rats single-pass perfusion in situ]. |
已发布 PubMed:五味子中木脂素的分离及其在 大肠癌中的抗增殖活性 Isolation of lignans from Schisandra chinensis with anti-proliferative activity in human colorectal carcinoma: 结构-活动关系。 Structure-activity relationships. |
已发布 PubMed:五味子中二苯并环辛二烯木脂素的保护作用抵抗pc12细胞中的β-淀粉样蛋白和高半胱氨酸橙花毒性。 Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells. |
已发布 PubMed:五味子果实1-o-甲基-果糖呋喃糖对b16f0黑素瘤细胞黑素生成的抑制作用。 Inhibitory effects of 1-O-methyl-fructofuranose from Schisandra chinensis fruit on melanogenesis in B16F0 melanoma cells. |
已发布 PubMed:五味子中二苯并环辛二烯木脂素的脂肪酸合酶抑制活性 Fatty acid synthase inhibitory activity of dibenzocyclooctadiene lignans isolated from Schisandra chinensis. |
已发布 PubMed:双盲 Double-blind, 安慰剂对照 placebo-controlled, 适应剂232对认知功能的单剂量影响的随机研究。 randomised study of single dose effects of ADAPT-232 on cognitive functions. |
已发布 PubMed:北五味子的二苯并环辛二烯木脂素可改善葡萄糖的体外吸收。 Dibenzocyclooctadiene lignans from Fructus Schisandrae Chinensis improve glucose uptake in vitro. |
已发布 PubMed:戈米菌素N的抗炎作用 Anti-inflammatory effects of gomisin N, 戈米辛 gomisin J, 从五味子的果实中分离出的五味子和五味子c。 and schisandrin C isolated from the fruit of Schisandra chinensis. |
已发布 PubMed:五味子精在g0 / g1中的生长抑制和细胞周期阻滞 Growth inhibition and cell cycle arrest in the G0/G1 by schizandrin, 从五味子分离的二苯并环辛二烯木脂素 a dibenzocyclooctadiene lignan isolated from Schisandra chinensis, 在t47d 类乳腺癌细胞上。 on T47D human breast cancer cells. |
已发布 PubMed: 戈米菌素 gomisin a诱导 冠状动脉内皮细胞中enos的ca2 +依赖性活化。 |
已发布 PubMed:五味子果实中木脂素通过nrf2的核积累诱导肝癌细胞中的第二阶段解毒酶nqo1。 Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. |
已发布 PubMed:液相色谱二极管阵列检测分析五味子和大鼠血浆中的木脂素 Analysis of lignans in Schisandra chinensis and rat plasma by high-performance liquid chromatography diode-array detection, 飞行时间质谱和四极杆离子阱质谱。 time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry. |
已发布 PubMed:五味子提取物诱导大鼠胸主动脉血管舒张的机制。 The mechanism of vasorelaxation induced by Schisandra chinensis extract in rat thoracic aorta. |
已发布 PubMed:五味子和五味子的分析。 Analysis of Schisandra chinensis and Schisandra sphenanthera. |
已发布 PubMed:五味子果实不同加工产物中的木脂素 [Lignans from different processed products of Schisandra chinensis fruits]. |
已发布 PubMed:五味子的五味子素c降低c6胶质瘤细胞的膜电位。 Wuweizisu C from Schisandra chinensis decreases membrane potential in C6 glioma cells. |
已发布 PubMed:从五味子果实中提取的五味子素具有抗炎作用。 Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill. |
已发布 PubMed:五味子乙素可增强脑线粒体的抗氧化状态和结构完整性 Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, 并防止大鼠脑缺血/再灌注损伤。 and protects against cerebral ischemia/reperfusion injury in rats. |
已发布 PubMed:压碎的多香果浆果的蒸汽蒸馏需要长达12 的操作才能完全耗尽植物材料。这种长期暴露于热蒸汽中对精油和水果其他成分的化学组成没有显着影响。 Structural characterization and identification of dibenzocyclooctadiene lignans in Fructus Schisandrae using electrospray ionization ion trap multiple-stage tandem mass spectrometry and electrospray ionization Fourier transform ion cyclotron resonance multiple-stage tandem mass spectrometry. |
已发布 PubMed:五味子乙素可增强肾脏线粒体的抗氧化状态 Schisandrin B Enhances Renal Mitochondrial Antioxidant Status, 功能和结构完整性 Functional and Structural Integrity, 并防止庆大霉素对大鼠的肾毒性。 and Protects against Gentamicin-Induced Nephrotoxicity in Rats. |
已发布 PubMed:长期的五味子素b治疗可减轻与年龄相关的线粒体抗氧化剂状态和各种组织功能能力的损害 Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, 并改善衰老的c57bl / 6j小鼠的存活率。 and improves the survival of aging C57BL/6J mice. |
已发布 PubMed: 五味子的戈米菌素 gomisin a诱导大鼠胸主动脉内皮依赖性和直接松弛。 |
已发布 PubMed:五味子素单体口服后五味子素的药代动力学比较 Pharmacokinetic comparisons of schizandrin after oral administration of schizandrin monomer, 五味子水提物和生脉散对大鼠的作用。 Fructus Schisandrae aqueous extract and Sheng-Mai-San to rats. |
已发布 PubMed: rp-lc RP-LC与爸爸同时测定生药草和五味子的商业干燥水提物中的四种五味子木脂素的方法的验证 |
已发布 PubMed:脂酶催化山茶精油甲酯与甘油三乙酸酯的酯交换反应合成结构性脂质,并初步评估其在小鼠中的降血脂作用。 Studies on lignan constituents from Schisandra chinensis (Turcz.) Baill. fruits using high-performance liquid chromatography/electrospray ionization multiple-stage tandem mass spectrometry. |
已发布 PubMed:五味子和五味子的不同提取物的组成和生物活性 Composition and biological activity of different extracts from Schisandra sphenanthera and Schisandra chinensis. |
已发布 PubMed:五味子素b降低感觉线粒体对钙离子诱导的通透性转变的敏感性,并防止小鼠肝脏中的四氯化碳毒性。 Schisandrin B decreases the sensitivity of mitochondria to calcium ion-induced permeability transition and protects against carbon tetrachloride toxicity in mouse livers. |
已发布 PubMed:五味子的富含酚的组分对h2o2诱导的sh-sy5y细胞凋亡的保护作用。 Protective effect of a phenolic-rich fraction from Schisandra chinensis against H2O2-induced apoptosis in SH-SY5Y cells. |
已发布 PubMed:五味子的五味子酚a通过影响pgp-底物复合物逆转p-糖蛋白介导的多药耐药性。 Schisandrol A from Schisandra chinensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes. |
已发布 PubMed:五味子乙素诱导的急性高甘油三酸酯血症的新型实验模型。 A novel experimental model of acute hypertriglyceridemia induced by schisandrin B. |
已发布 PubMed:五味子及其制剂中木脂素含量测定的研究进展 [Research progress on determination of lignans from Schiandra chinensis and its preparations]. |
已发布 PubMed:高速逆流色谱法从五味子茎中制备分离纯化和纯化脱氧五味子和γ-五味子。 Preparative separation and purification of deoxyschisandrin and gamma-schisandrin from Schisandra chinensis (Turcz.) Baill by high-speed counter-current chromatography. |
已发布 PubMed:五味子乙素部分地通过诱导大鼠hsp25和hsp70表达来保护心肌缺血-再灌注损伤。 Schisandrin B protects myocardial ischemia-reperfusion injury partly by inducing Hsp25 and Hsp70 expression in rats. |
已发布 PubMed:五味子的二苯并环辛二烯木脂素可保护大鼠皮质细胞的原代培养物免受谷氨酸诱导的毒性。 Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity. |
已发布 PubMed:合成吸附剂在制备型正相液相色谱中的应用。 Use of synthetic adsorbents in preparative normal-phase liquid chromatography. |
已发布 PubMed:[对五味子保尔的精油的分析。与gc / ms]。 [Analysis of the essential oil of Schisandra chinensis (Turcz.) Baill. with GC/MS]. |
已发布 PubMed:与五味子素b和大黄素相比,五味子果实富含木脂素的提取物和何首乌根中含蒽醌的提取物的体内抗氧化作用。 In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. |
已发布 PubMed: 五味子素b保护他克林和bis(7)-他克林诱导的肝毒性并增强小鼠的认知功能 |
已发布 PubMed:制剂equipguard对激素反应性和激素难治性前列腺癌细胞的作用 Effects of herbal preparation Equiguard on hormone-responsive and hormone-refractory prostate carcinoma cells: 机械研究。 mechanistic studies. |
已发布 PubMed:五味子素b通过增强dt-黄递酶活性来预防甲萘醌引起的肝毒性。 Schisandrin B protects against menadione-induced hepatotoxicity by enhancing DT-diaphorase activity. |
已发布 PubMed:五味子素b和二羧酸二苯二甲酸二苯酯(ddb)对四氯化碳中毒小鼠肝线粒体谷胱甘肽氧化还原状态的不同影响。 Differential effect of schisandrin B and dimethyl diphenyl bicarboxylate (DDB) on hepatic mitochondrial glutathione redox status in carbon tetrachloride intoxicated mice. |
已发布 PubMed:ccl4中毒模型评估五味子对第一阶段药物代谢的保护作用。 Evaluation of the protective effects of Schisandra chinensis on Phase I drug metabolism using a CCl4 intoxication model. |
已发布 PubMed:基质和流体乙醇浓度对五味子衍生物的超临界流体萃取效率的影响 Effect of plant matrix and fluid ethanol concentration on supercritical fluid extraction efficiency of schisandrin derivatives. |
已发布 PubMed:五味子的木酚素提取物对黄曲霉毒素b1和氯化镉诱导的大鼠肝毒性的影响。 Effect of a lignan-enriched extract of Schisandra chinensis on aflatoxin B1 and cadmium chloride-induced hepatotoxicity in rats. |
已发布 PubMed:五味子素b通过增强小鼠肝脏中的线粒体谷胱甘肽氧化还原状态来防止四氯化碳毒性。 Schisandrin B protects against carbon tetrachloride toxicity by enhancing the mitochondrial glutathione redox status in mouse liver. |
已发布 PubMed:五味子的有效成分的研究。等。五味子素a的结构 Studies on the active principles of Schisandra sphenanthera Rehd. et Wils. The structures of schisantherin A, B, C, D, E, 以及相关化合物。 and the related compounds. |
已发布 PubMed:五味子果实中木脂素分布的测定与研究。 [Determination and study of lignan distribution in the fruits of Schisandra chinensis (Turcz.) Baill]. |