bergaptene
5-methoxypsoralen

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    484-20-8佛手柑> 98% 484-20-8 Bergapten >98%
    bergapten是一种补骨脂素,可以光活化,并且能够交联dna Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, 共价修饰蛋白质和脂质 covalently modifying proteins and lipids, 从而抑制细胞复制。 and consequently inhibiting cell replication.
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    b2840 bergaptene> 98.0%(气相色谱) B2840 Bergaptene >98.0%(GC)
Name:4-甲氧基呋喃[3 4-methoxyfuro[3, 2-g] 铬 chromen-7-one
CAS号 CAS Number: 484-20-8Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:207-604-5
FDA UNII:4FVK84C92X
nikkaji网站 Nikkaji Web:J12.563F
贝尔斯坦数 Beilstein Number:0019560
MDL :mfcd00010272 MFCD00010272
XlogP3-AA:2.30(est) 2.30 (est)
分子量 Molecular Weight:216.19256000
式 Formula:c12 h8 o4 C12 H8 O4
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:natural substances and extractives
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
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谷歌学术 Google Scholar: with word "volatile"搜索 Search
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pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
出现 Appearance:绿晶体(est) green crystals (est)
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 188.00 to 100.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 412.00 to 413.00 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 398.00 °F. tcc TCC ( 203.20 °C. ) (est)
logp(o / w) logP (o/w): 2.035(est) 2.035 (est)
溶于 Soluble in:
 alcohol
 水 water, 810.5 mg / l @ 25°c(est) 810.5 mg/L @ 25 °C (est)
不溶于 Insoluble in:
 水 water
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
香柠檬> 98% Bergapten >98%
气味 Odor: characteristic
采用 Use: bergapten是一种补骨脂素,可以光活化,并且能够交联dna Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, 共价修饰蛋白质和脂质 covalently modifying proteins and lipids, 从而抑制细胞复制。 and consequently inhibiting cell replication.
外合成 ExtraSynthese
仅供实验/研究使用。 For experimental / research use only.
佛手柑(hplc)≥99% Bergapten (HPLC) ≥99%
印度世界贸易 Indo World Trading
Bergapten
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
佛手柑 Bergaptene
西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich
仅供实验/研究使用。 For experimental / research use only.
5-甲氧基补骨脂素99% 5-Methoxypsoralen 99%
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
bergaptene> 98.0%(gc) Bergaptene >98.0%(GC)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
口鼠 oral-rat LD50 > 30000 mg/kg
"补骨脂素 补骨脂素 Psoralens in 化妆品 Cosmetics and 皮肤科 Dermatology, 国际研讨会论文集 Proceedings of the International Symposium, 巴黎 Paris, 1981," 卡恩 Cahn, j. J., 等。 et al., eds。 eds., 巴黎 Paris, 法国佩加蒙新闻社 Pergamon Press France, 1981卷-- 1981Vol. -, pg。 303 Pg. 303, 1981.

老鼠 oral-老鼠 mouse LD50 8100 mg/kg
"补骨脂素 补骨脂素 Psoralens in 化妆品 Cosmetics and 皮肤科 Dermatology, 国际研讨会论文集 Proceedings of the International Symposium, 巴黎 Paris, 1981," 卡恩 Cahn, j. J., 等。 et al., eds。 eds., 巴黎 Paris, 法国佩加蒙新闻社 Pergamon Press France, 1981卷-- 1981Vol. -, pg。 303 Pg. 303, 1981.

几内亚口服 oral-guinea 猪 pig LD50 9000 mg/kg
"补骨脂素 补骨脂素 Psoralens in 化妆品 Cosmetics and 皮肤科 Dermatology, 国际研讨会论文集 Proceedings of the International Symposium, 巴黎 Paris, 1981," 卡恩 Cahn, j. J., 等。 et al., eds。 eds., 巴黎 Paris, 法国佩加蒙新闻社 Pergamon Press France, 1981卷-- 1981Vol. -, pg。 303 Pg. 303, 1981.

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: natural substances and extractives
推荐使用高达8的bergaptene Recommendation for bergaptene usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐的佛手柑风味使用水平最高为 Recommendation for bergaptene flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
临床 Clinicaltrials.gov :search
nlm NLM有害物质数据库 :搜索 Search
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :2355
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:2
4-甲氧基呋喃[3 4-methoxyfuro[3, 2-g] 铬 chromen-7-one
chemidplus Chemidplus:0000484208
epa / noaa客串 EPA/NOAA CAMEO:有害物质 hazardous materials
技术 RTECS:CAS#484-20-8的lv1300000 LV1300000 for cas# 484-20-8
 
参考资料 References:
 4-甲氧基呋喃[3 4-methoxyfuro[3, 2-g] 铬 chromen-7-one
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):2355
pubchem(sid) Pubchem (sid):134975339
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
代谢组学数据库 Metabolomics Database:搜索 Search
KEGG (GenomeNet):C01557
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB30637
食物 FooDB:FDB002542
出口关税代码 Export Tariff Code:2932.99.7000
雾度图 Haz-Map:视图 View
典型的g.c. Typical G.C.
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
efsa EFSA更新监测食品中呋喃水平的结果 :阅读报告 Read Report
efsa EFSA以前的报告 : 食品中呋喃水平监测的结果 Results on the monitoring of furan levels in food:阅读报告 Read Report
欧洲反腐败委员会关于食品中呋喃的临时调查结果的efsa EFSA报告 :阅读报告 Read Report
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None found
 
潜在用途 Potential Uses:
没找到 None found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 茴香种子 fennel seed
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 茴香组织培养 anise tissue culture
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 佛手柑皮 bergamot peel
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 香菜植物 caraway plant
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 香菜种子 coriander seed
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 胡萝卜植物 carrot plant
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 胡萝卜种子 carrot seed
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 芹菜叶 celery leaf
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 芹菜叶celery leaf wax
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 芹菜植物 celery plant
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 芹菜种子 celery seed
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 香菜 coriander fruit
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 香菜种子 coriander seed
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 莳萝种子 dill seed
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 莳萝籽油 dill seed oil
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 茴香种子 fennel seed
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 fig
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 无花果 fig fruit
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 无花果叶 fig leaf
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 无花果植物 fig plant
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 无花果汁 fig sap
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 赫拉克勒姆香菜果实油土耳其@ heracleum paphlagonicum czeczott fruit oil turkey @ <0.10%
Data gc GC 搜索 Search Trop Picture
 柠檬果油 lemon fruit oil
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 柠檬植物 lemon plant
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 青柠果 lime fruit
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 独活的水果 lovage fruit
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 独根 lovage root
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 橙色果皮 orange pericarp
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 欧芹果 parsley fruit
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 香菜叶 parsley leaf
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 欧芹叶油@ 0.04% parsley leaf oil @ 0.04%
Data gc GC 搜索 Search Trop Picture
 欧芹植物 parsley plant
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 香菜根 parsley root
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 香菜种子 coriander seed
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 欧芹组织培养 parsley tissue culture
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 防风草根 parsnip root
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 防风草种子 parsnip seed
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 芸香工厂 rue plant
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 番茄 tomato
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同义词 Synonyms:
 佛手柑 bergamotcamphor
 bergaptan
7H-furo[3,2-g] [1] benzopyran-7-one 2-g][1]benzopyran-7-one, 4-methoxy-
 heraclin
6-hydroxy-4-methoxy-5-benzo呋喃 furan 丙烯酸 acrylic acid γ-内酯 gamma-lactone
 majudin
4-methoxy psoralen
5-methoxy psoralen
5-methoxy-2H-furo[3,2-g]铬 chromen-2-one
5-methoxy-6,7-呋喃香豆素 呋喃 furano香豆素 coumarin
4-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one
4-methoxy-7H-furo[3,2-g] [1] benzopyran-7-one 2-g][1]benzopyran-7-one
4-methoxy-7H-furo[3, 2-g] 铬 chromen-7-one
4-methoxy-furo[3, 2-g] 铬 chromen-7-one
5-methoxy呋喃 furano[3,2-g]铬 chromen-2-one
5-methoxy呋喃香豆素 呋喃 furano香豆素 coumarin
4-methoxyfuro(3,2-g)铬 chromen-7-one
4-methoxyfuro[3,2-g]benzopyrane-7-one
4-methoxyfuro[3, 2-g] 铬 chromen-7-one
5-methoxypsoralen
O-methyl香豆酚 bergaptol
 

文章 Articles:

已发布 PubMed:初生花生的抗糖尿病活性的体外和体内初步评估。及其线性呋喃香豆素。 Preliminary In Vitro and In Vivo Evaluation of Antidiabetic Activity of Ducrosia anethifolia Boiss. and Its Linear Furanocoumarins.
已发布 PubMed:与褪黑激素的潜在药物相互作用。 Potential drug interactions with melatonin.
已发布 PubMed:等价因子概念在呋喃香豆素混合物的光毒性和遗传毒性中的应用。 Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures.
已发布 PubMed:补骨脂素诱导的 类细胞内链间交联的定量和修复。 Quantification and repair of psoralen-induced interstrand crosslinks in human cells.
已发布 PubMed:高效液相色谱法同时测定化妆品中的八种呋喃香豆素,液相色谱-串联质谱法验证 [Simultaneous determination of eight furocoumarines in cosmetics by high performance liquid chromatography and verification by liquid chromatography-tandem mass spectrometry].
已发布 PubMed:植物生物活性化合物对源自 果树的解偶联酶的污染3 Contamination of deconjugation enzymes derived from Helix pomatia with the plant bioactive compounds 3,3'-diindolylmethane, 5-methoxypsoralen, 和8-甲氧基补骨脂素 and 8-methoxypsoralen.
已发布 PubMed:通过使用lc-ms / ms方法研究在狗血浆中佛手柑的药代动力学研究。 Pharmacokinetic studies of bergapten in dog plasma by using a LC-MS/MS method studies.
已发布 PubMed:大麦草碱同时测定 Simultaneous determination of scopoletin, psoralen, bergapten, 黄花毒素 xanthotoxin, 醋酸哥伦比汀 columbianetin acetate, 欧前胡素 imperatorin, 当归口服当归提取物后,通过lc-ms / ms对大鼠血浆中的臭虫 osthole和iso欧前胡素 imperatorin进行药代动力学研究。
已发布 PubMed:bergapten通过smad4介导的泛素化诱导乳腺癌细胞中的er耗竭。 Bergapten induces ER depletion in breast cancer cells through SMAD4-mediated ubiquitination.
已发布 PubMed:桔皮己烷提取物的化学组成和抗结核分枝杆菌活性的一些成分。 Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents.
已发布 PubMed:对抗性调节 Antagonistic regulation, 协同防御 yet synergistic defense: 精和蛋白酶抑制剂对cow豆布鲁氏call茧/愈合组织发育的影响 effect of bergapten and protease inhibitor on development of cowpea bruchid Callosobruchus maculatus.
已发布 PubMed:胺对芸芸芸苔培养物中芽增殖和呋喃香豆素生成的影响 Effect of polyamines on shoot multiplication and furanocoumarin production in Ruta graveolens cultures.
已发布 PubMed:一种新的鞘脂和呋喃香豆素,具有无花果榕的抗菌活性。 A new sphingolipid and furanocoumarins with antimicrobial activity from Ficus exasperata.
已发布 PubMed:fr活not种子中所含的化学成分 [Chemical constituents contained in seeds of Notopterygium franchetii].
已发布 PubMed:5-甲氧基补骨脂素对乙酰氨基酚诱导的小鼠肝毒性的保护作用。 Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:lc-ms / ms法测定大鼠血浆中佛手柑的药代动力学 [Phamacokinetic study of bergapten in rats plasma by LC-MS/MS].
已发布 PubMed:汉族 群中香豆素对cyp2a13 * 4催化活性和cyp2a13多态性的研究。 An investigation of the catalytic activity of CYP2A13*4 with coumarin and polymorphisms of CYP2A13 in a Chinese Han population.
已发布 PubMed:天然香豆素作为β-分泌酶抑制剂的构效关系。 Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.
已发布 PubMed:葡萄柚汁中的主要呋喃香豆素II Major furocoumarins in grapefruit juice II: 光毒性 phototoxicity, 光遗传毒性 photogenotoxicity, 和抑制效能与细胞色素p450 3a4活性的关系。 and inhibitory potency vs. cytochrome P450 3A4 activity.
已发布 PubMed:流感样综合征 Flu-like syndrome, 5-甲氧基补骨脂素引起的支气管收缩和发烧 bronchoconstriction and fever caused by 5-methoxypsoralen: 第一次病例报告和文献复习。 the first case report and literature review.
已发布 PubMed:补骨脂素加紫外线a疗法与生物制剂在中度至重度慢性斑块牛皮癣中的疗效 Efficacy of psoralen plus ultraviolet A therapy vs. biologics in moderate to severe chronic plaque psoriasis: 病历的回顾性数据分析。 retrospective data analysis of a patient registry.
已发布 PubMed:5-甲氧基补骨脂素在恒河猴中的经皮渗透。 Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys.
已发布 PubMed:四种线性呋喃香豆素的抗惊厥作用 Anticonvulsant effects of four linear furanocoumarins, bergapten, 欧前胡素 imperatorin, 羟哌丁宁 oxypeucedanin, 和花椒毒素 and xanthotoxin, 在小鼠最大的电击诱发癫痫发作模型中 in the mouse maximal electroshock-induced seizure model: 一项比较研究。 a comparative study.
已发布 PubMed:榕树乳状液中天然呋喃香豆素的免疫毒性活性。反对埃及伊蚊 Immunotoxicity activity of natural furocoumarins from milky sap of Ficus carica L. against Aedes aegypti L.
已发布 PubMed:三甲基Angelicin减少IL-8转录并增强cftr功能 Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.
已发布 PubMed:[高效液相色谱法测定补骨脂素 [High-performance liquid chromatography for determination of psoralene, 希尔塔 hirta vahl中的佛手柑和芹菜素]。
已发布 PubMed:CYP2A13单核苷酸多态性对5-甲氧基补骨脂素代谢的影响。 The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsoralen.
已发布 PubMed:柑橘佛手柑和c。的体外光诱导细胞毒性活性梅迪卡 简历。 diamante剥离香精油并鉴定出活性香豆素。 In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins.
已发布 PubMed:用衍生自5-甲氧基补骨脂素的uv-a辐照的光产物处理后,类胡萝卜素诱导慢性粒细胞白血病k562细胞。 Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.
已发布 PubMed:咖啡因,作为减少光毒性的光保护剂。 Caffeine as a photoprotective agent for diminishing phototoxicity.
已发布 PubMed:光过敏性接触性皮炎对心形榕中的8-甲氧基补骨脂素。 Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica.
已发布 PubMed:克氏小球菌对佛手柑和黄腐毒素的生物转化。 Biotransformation of bergapten and xanthotoxin by Glomerella cingulata.
已发布 PubMed:紫茎泽兰茎皮中的抗菌香豆素。 Antimicrobial coumarins from the stem bark of Afraegle paniculata.
已发布 PubMed:快速表征交叉链接 Rapid characterization of cross-links, 单加合物 mono-adducts, lc-uv / esi-ms和irmpd质谱分析了补骨脂素与脱氧寡核苷酸非共价结合。 and non-covalent binding of psoralens to deoxyoligonucleotides by LC-UV/ESI-MS and IRMPD mass spectrometry.
已发布 PubMed:bergapten结合紫外线照射会影响乳腺癌细胞的生存信号。 Breast cancer cell survival signal is affected by bergapten combined with an ultraviolet irradiation.
已发布 PubMed:花椒毒素的同时灵敏测定 Simultaneous and sensitive determination of xanthotoxin, psoralen, 液相色谱-电喷雾电离质谱法测定大鼠血浆中的异宾果素和佛手柑 isoimpinellin and bergapten in rat plasma by liquid chromatography-electrospray ionization mass spectrometry.
已发布 PubMed:补骨脂素和佛手柑 Psoralen and bergapten: 在计算机代谢和药物治疗白癜风的毒理分析中的应用。 in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.
已发布 PubMed:相对光致突变潜能的概念在v79细胞中所选呋喃香豆素中的应用。 Application of the concept of relative photomutagenic potencies to selected furocoumarins in V79 cells.
已发布 PubMed:5-甲氧基补骨脂素加紫外线(uv)a在重度特应性皮炎的治疗中优于中等剂量的uva1 5-Methoxypsoralen plus ultraviolet (UV) A is superior to medium-dose UVA1 in the treatment of severe atopic dermatitis: 随机交叉试验。 a randomized crossover trial.
已发布 PubMed:呋喃香豆素 Furanocoumarins: 新的拓扑异构酶I抑制剂,来自芸香。 novel topoisomerase I inhibitors from Ruta graveolens L.
已发布 PubMed:v79细胞中次黄嘌呤磷酸核糖基转移酶测定中呋喃香豆素和石灰蛋白的相对光致突变性。 Relative photomutagenicity of furocoumarins and limettin in the hypoxanthine phosphoribosyl transferase assay in V79 cells.
已发布 PubMed:5-甲氧基补骨脂素对支气管上皮细胞il-8基因表达的调节 Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen.
已发布 PubMed:[来自当归的酪氨酸酶抑制剂]。 [Tyrosinase inhibitor from Angelica dahurica roots].
已发布 PubMed:芥根中的佛手柑对促炎细胞因子产生的影响 Effect of bergapten from Heracleum nepalense root on production of proinflammatory cytokines.
已发布 PubMed:贝加普滕的证据 Evidence that bergapten, 与其光活化无关 independently of its photoactivation, 增强p53基因表达并诱导 乳腺癌细胞凋亡。 enhances p53 gene expression and induces apoptosis in human breast cancer cells.
已发布 PubMed:印度芹菜种子(果实)的植物起源。 Botanical origin of Indian celery seed (fruit).
已发布 PubMed:口服5-甲氧基补骨脂素后补骨脂素加紫外线红斑发展的时间过程。 Time course for development of psoralen plus ultraviolet A erythema following oral administration of 5-methoxypsoralen.
已发布 PubMed:当归抗菌活性级分的化学成分 [Chemical constituents of antibacterial activity fraction of Angelica polymorpha].
已发布 PubMed:超声波法从植物中提取抗氧化剂及其抗氧化能力。 Extraction of antioxidants from plants using ultrasonic methods and their antioxidant capacity.
已发布 PubMed:4-苯氧基丁氧基取代的杂环-淋巴细胞钾通道kv1.3阻滞剂的结构-活性关系研究。 4-Phenoxybutoxy-substituted heterocycles--a structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3.
已发布 PubMed:佛手柑细胞培养物中香菜碱邻甲基转移酶的组成型表达。 Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures.
已发布 PubMed:[葡萄柚汁和健康食品中呋喃香豆素的含量]。 [Contents of furanocoumarins in grapefruit juice and health foods].
已发布 PubMed:香豆素 Coumarin, 具有抗胆碱酯酶活性的蒽醌和二苯乙烯衍生物。 anthroquinone and stilbene derivatives with anticholinesterase activity.
已发布 PubMed:柑桔果皮提取物中的杀虫成分的分离与鉴定。 Isolation and identification of insecticidal components from Citrus aurantium fruit peel extract.
已发布 PubMed:脂质纳米颗粒作为补骨脂素局部给药的载体 Lipid nanoparticles as vehicles for topical psoralen delivery: 固体脂质纳米颗粒(sln)与纳米结构脂质载体(nlc)。 solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC).
已发布 PubMed:生物测定法对果酱中天然芳烃受体激动剂的鉴定。 Bioassay directed identification of natural aryl hydrocarbon-receptor agonists in marmalade.
已发布 PubMed:呋喃香豆素光解产物可诱导 红系细胞分化。 Furocoumarins photolysis products induce differentiation of human erythroid cells.
已发布 PubMed: 实时基于荧光的脱氧核糖核酸 DNA呋喃香豆素光加合物检测。
已发布 PubMed:短毛埃塞克氏菌提取物及其成分的体外抗血浆活性 In vitro antiplasmodial activity of extract and constituents from Esenbeckia febrifuga, 一种传统上用于治疗巴西亚马逊河疟疾的植物。 a plant traditionally used to treat malaria in the Brazilian Amazon.
已发布 PubMed: [使用液晶显示器 LC-MS / MS同时测定化妆品中的8-甲氧基补骨脂素和5-甲氧基补骨脂素]。
已发布 PubMed:鉴定芸香l。代谢物在非生物激发子的存在下积累。 Identification of Ruta graveolens L. metabolites accumulated in the presence of abiotic elicitors.
已发布 PubMed:高效液相色谱法同时测定虎尾草中5种活性成分 [Simultaneous determination of 5 active components in Fructus Cnidii by HPLC].
已发布 PubMed:线粒体和p53在puva诱导的 类角质形成细胞系nctc-2544凋亡中的重要作用。 Central role of mitochondria and p53 in PUVA-induced apoptosis in human keratinocytes cell line NCTC-2544.
已发布 PubMed:γ-珠蛋白核糖核酸诱导 Induction of gamma-globin mRNA, 在存在呋喃香豆素衍生物的情况下,经紫外线照射的 红系细胞中红系的分化和凋亡。 erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.
已发布 PubMed:茴香成分对 肝细胞色素p450 3a4的抑制作用 Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): 基于机制的灭活剂的识别和表征。 identification and characterization of a mechanism-based inactivator.
已发布 PubMed:香豆素衍生物通过成骨细胞中的p38和erk依赖性途径增强香豆素衍生物的骨形态发生蛋白2表达和骨形成。 Enhancement of bone morphogenetic protein-2 expression and bone formation by coumarin derivatives via p38 and ERK-dependent pathway in osteoblasts.
已发布 PubMed:成分 Constituents, 楠木粗提取物和精油的生物活性和质量控制参数 。 biological activities and quality control parameters of the crude extract and essential oil from Arracacia tolucensis var. multifida.
已发布 PubMed: 前胡 Peucedanum 奢华主义者 luxurians的香豆素。
已发布 PubMed: 圆叶特发性 Treculia obovoidea(桑科)的甲醇提取物和化合物的抗菌活性。
已发布 PubMed:ali藜果实化学成分的研究 [Studies on chemical constituents from fruits of Paliurus ramosissimus].
已发布 PubMed:意外过量的光化学疗法(puva)引起的灼伤。 Burns caused by accidental overdose of photochemotherapy (PUVA).
已发布 PubMed:与8-甲氧基补骨脂素和5-甲氧基补骨脂素相比,太阳模拟器引起的呋喃喹啉生物碱三甲胺的光毒性。 Solar simulator-induced phototoxicity of the furoquinoline alkaloid dictamnine compared to 8-methoxypsoralen and 5-methoxypsoralen.
已发布 PubMed:高效液相色谱法同时测定 和点地梅科药物中甲氧基补骨脂素的尿代谢产物 Simultaneous determination of urinary metabolites of methoxypsoralens in human and Umbelliferae medicines by high-performance liquid chromatography.
已发布 PubMed:加利福尼亚出售的葡萄柚汁产品中引起药物相互作用的活性成分含量变化。 Variations in content of active ingredients causing drug interactions in grapefruit juice products sold in California.
已发布 PubMed:豆科植物成分抑制 细胞色素p-450 1a2(hcyp1a2)活性和hcyp1a2介导的黄曲霉毒素b1致突变性。 Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.
已发布 PubMed:一种定量测定植物化学制剂胶囊和片剂中呋喃香豆素的方法。 A method for quantitative determination of furanocoumarins in capsules and tablets of phytochemical preparations.
已发布 PubMed:新的含补骨脂素的凝胶和面霜与沐浴液的光毒性。 Phototoxicity of new psoralen-containing gels and creams versus bath PUVA.
已发布 PubMed:啤酒酵母作为评估化学诱导的光毒性的预筛选方法的用途。 Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.
已发布 PubMed:甲真菌性补骨脂对5-甲氧基补骨脂加紫外线的疗效 Efficacy of 8-methoxypsoralen vs. 5-methoxypsoralen plus ultraviolet A therapy in patients with mycosis fungoides.
已发布 PubMed:对5-甲氧基补骨脂素(5-mop)对大鼠胃和结肠以及 胃和结肠肿瘤细胞系中芳胺正乙酰转移酶活性的影响 Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines.
已发布 PubMed:5-(3-苯基丙氧基)补骨脂素和5-(4-苯基丁氧基)补骨脂素 5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: 光毒性的机理研究。 mechanistic studies on phototoxicity.
已发布 PubMed:柑橘柠檬苦素的抗氧化活性 Antioxidant activity of citrus limonoids, 类黄酮 flavonoids, 和香豆素。 and coumarins.
已发布 PubMed:柠檬外皮香豆素类化合物的研究 [Study on coumarin compounds from Exocarpium Citri Grandis].
已发布 PubMed:2d nmr光谱分析当归种子中的argelicin。 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica.
已发布 PubMed:通过逐步增加流动相的流速,使用高速逆流色谱法从药用植物凤尾兰中制备佛手柑和欧前胡素的制备分离和纯化。 Preparative isolation and purification of bergapten and imperatorin from the medicinal plant Cnidium monnieri using high-speed counter-current chromatography by stepwise increasing the flow-rate of the mobile phase.
已发布 PubMed:原卟啉ix的光毒性 Phototoxicity of protoporphyrin IX, 精氨酸双原卟啉和n diarginine diprotoporphyrinate and N,正二苯基丙氨酰原卟啉对 成纤维细胞和角质形成细胞的体外作用 N-diphenylalanyl protoporphyrin toward human fibroblasts and keratinocytes in vitro: 5-甲氧基补骨脂素的作用。 effect of 5-methoxypsoralen.
已发布 PubMed:苜蓿主要代谢产物的遗传变异;草食动物可以充当选择剂吗? Genetic variation in primary metabolites of Pastinaca sativa; can herbivores act as selective agents?
已发布 PubMed:一种使用液相色谱法快速测定植物药口服溶液中补骨脂素的方法。 A method for fast determination of psoralens in oral solutions of phytomedicines using liquid chromatography.
已发布 PubMed:抑制传统药物中呋喃香豆素的dna聚合反应和抗真菌特异性。 Inhibition of DNA polymerization and antifungal specificity of furanocoumarins present in traditional medicines.
已发布 PubMed:α-亚甲基-γ-丁内酯-补骨脂素异二聚体的合成和光细胞毒性活性。 Synthesis and photocytotoxic activity of new alpha-methylene-gamma-butyrolactone-psoralen heterodimers.
已发布 PubMed:芸香叶中的植物毒素。 Phytotoxins from the leaves of Ruta graveolens.
已发布 PubMed:豆蔻中呋喃香豆素的生物合成佛手酚邻甲基转移酶的克隆。 Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase.
已发布 PubMed:香根草根中的呋喃香豆素。 The furanocoumarins in the roots of Heracleum sibiricum L.
已发布 PubMed:胸腺嘧啶残基键合补骨脂素化合物激发态的理论研究。 Theoretical study on the excited states of psoralen compounds bonded to a thymine residue.
已发布 PubMed:马可夫式 Marko通过 vian chemicals "in 硅片 silico" 设计 design (行军内部 MARCH-INSIDE), 一种有前途的计算机辅助分子设计方法 a promising approach for computer-aided molecular design I: 发现抗癌化合物。 discovery of anticancer compounds.
已发布 PubMed:底物和抑制剂在cyp6b1催化位点的分子对接 Molecular docking of substrates and inhibitors in the catalytic site of CYP6B1, 昆虫细胞色素p450单加氧酶。 an insect cytochrome p450 monooxygenase.
已发布 PubMed:5-甲氧基补骨脂素(5-mop)对 肝癌细胞系细胞凋亡和细胞周期的影响 Effect of 5-methoxypsoralen (5-MOP) on cell apoptosis and cell cycle in human hepatocellular carcinoma cell line.
已发布 PubMed:补骨脂素的 毒性。 Reproductive toxicity of the psoralens.
已发布 PubMed:5-甲氧基补骨脂素从局部剂型的皮肤渗透。 Skin permeation of 5-methoxypsoralen from topical dosage forms.
已发布 PubMed:局部应用后5-甲氧基补骨脂素皮肤浓度的体外和体内研究。 In vitro and in vivo study of 5-methoxypsoralen skin concentration after topical application.
已发布 PubMed:佛手柑醚提取物中的两种天然香豆素的杀鼠活性。 Rodenticidal activity of two natural coumarines from ether extract of Citrus bergamia.
已发布 PubMed: [关于杜氏半夏的化学成分的研究。驻在谢赫的残忍的 garcile dunn ex shan]。
已发布 PubMed:补骨脂素对类芬顿反应产生活性氧的影响 Effect of psoralens on Fenton-like reaction generating reactive oxygen species.
已发布 PubMed:微透析-气相色谱-质谱法评估银屑病患者真皮中8-甲氧基补骨脂素的有效性 Validation of a microdialysis-gas chromatographic-mass spectrometric method to assess 8-methoxypsoralen in psoriatic patient dermis.
已发布 PubMed: 血清中5-甲氧基补骨脂素的测定。 Determination of 5-methoxypsoralen in human serum.
已发布 PubMed:5-甲氧基补骨脂素和西咪替丁对r的体内影响 In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,大鼠中的华法林代谢。 S-warfarin metabolism in rat.
已发布 PubMed:茶 Tea: 不道德 not immoral, 非法 illegal, 或发胖 or fattening, 但这是无害的吗? but is it innocuous?
已发布 PubMed:口服5-甲氧基补骨脂素会影响sprague-dawley大鼠体内2-氨基芴的分布和代谢。 Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats.
已发布 PubMed:扎本植物光性皮炎 Zabon phytophotodermatitis: 第一例报告是由于柑橘最大。 first case reports due to Citrus maxima.
已发布 PubMed:srs1和srs6中的氨基酸对于cyp6b1v1的呋喃香豆素代谢至关重要 Amino acids in SRS1 and SRS6 are critical for furanocoumarin metabolism by CYP6B1v1, 细胞色素p450单加氧酶。 a cytochrome P450 monooxygenase.
已发布 PubMed:保存条件对呋喃香豆素水平的影响 Effects of storage conditions on furocoumarin levels in intact, 切碎的 chopped, 或均质的欧洲防风草。 or homogenized parsnips.
已发布 PubMed: chalcones Chalcones和dorstenia dorstenia Dorstenia 肾上腺素 prorepens和dorstenia dorstenia Dorstenia 曾克里 zenkeri的其他成分。
已发布 PubMed:同时 Simultaneous 判定 determination of 呋喃香豆素 呋喃香豆素 呋喃 furano香豆素 香豆素 coumarins in 输液 infusions and 汤剂 decoctions from "carapiá Carapiá" (dorstenia dorstenia 种类 species) by by 高性能的 高 high-性能 performance 液体 liquid 色谱法 chromatography.
已发布 PubMed: dorstenin dorstenin在大肠杆菌和酿酒酵母菌株中诱导的光敏和突变。 , 从dorstenia dorstenia bahiensis bahiensis分离出来的补骨脂素类似物。
已发布 PubMed:葡萄柚类黄酮抑制 cyp3a4活性 Inhibition of human CYP3A4 activity by grapefruit flavonoids, 呋喃香豆素和相关化合物。 furanocoumarins and related compounds.
已发布 PubMed:在光化学疗法中对5-甲氧基补骨脂素有过敏反应。 Anaphylaxis to 5-methoxypsoralen during photochemotherapy.
已发布 PubMed:液相色谱法快速简便地测定主题溶液中的补骨脂素。 Simple and rapid determination of psoralens in topic solutions using liquid chromatography.
已发布 PubMed:来自云杉小核藻的吲哚吡喃并喹唑啉生物碱。 Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.
已发布 PubMed:西必利松对刺激节点兴奋过程的影响 Effects of silperisone on the excitation process in Ranvier nodes.
已发布 PubMed:对佛手柑香薰油的意外大疱光毒性反应。 Accidental bullous phototoxic reactions to bergamot aromatherapy oil.
已发布 PubMed:口服银屑病患者血浆和5-甲氧基补骨脂素的皮肤浓度。 Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration.
已发布 PubMed:呋喃香豆素在芹菜和欧洲防风草中 Furanocoumarins in celery and parsnips: 方法和加拿大多年调查。 method and multiyear Canadian survey.
已发布 PubMed:烷氧基补骨脂素对更结节电压门控离子通道的影响 Effects of three alkoxypsoralens on voltage gated ion channels in Ranvier nodes.
已发布 PubMed: 补骨脂素对雄性威士达 Wistar大鼠的 功能有不利影响。
已发布 PubMed:皮肤伦理重建 类表皮的高灵敏度体外光毒性测定技术的发展。 Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.
已发布 PubMed:[Heracl'eum mantegazzi'anum: 光敏化]。 photosensitization].
已发布 PubMed:塞维利亚橙汁-非洛地平相互作用 Seville orange juice-felodipine interaction: 与稀柚子汁和呋喃香豆素的含量进行比较。 comparison with dilute grapefruit juice and involvement of furocoumarins.
已发布 PubMed:葡萄柚汁中呋喃香豆素衍生物对caco-2细胞摄取长春碱影响以及对细胞色素p450 3a4活性的影响。 Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.
已发布 PubMed:日粮补骨脂素可诱导c57小鼠肝毒性。 Dietary psoralens induce hepatotoxicity in C57 mice.
已发布 PubMed:在储存过程中,富含维生素o3和omega6多不饱和脂肪酸新鲜和喷雾干燥鸡蛋中的脂质氧化受到饮食维生素e和角黄素补充的影响。 K(+) channel-blocking alkoxypsoralens inhibit the immune response of encephalitogenic T line cells and lymphocytes from Lewis rats challenged for experimental autoimmune encephalomyelitis.
已发布 PubMed:CYP3A4抑制剂的含量 Content of CYP3A4 inhibitors, 柚皮苷 naringin, 柚子和柚子汁产品中的柚皮素和香柠檬素。 naringenin and bergapten in grapefruit and grapefruit juice products.
已发布 PubMed:普瓦治疗成功的广义环状肉芽肿。 Generalised granuloma annulare successfully treated with PUVA.
已发布 PubMed:先前患有氟氯西林肝炎的患者发生5-甲氧基补骨脂素引起的肝炎。 Hepatitis from 5-methoxypsoralen occurring in a patient with previous flucloxacillin hepatitis.
已发布 PubMed:与口服puva疗法相比,浴puva的致癌风险。 Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy.
已发布 PubMed:光化学治疗药物5-mop和8-mop的新四环类似物 New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8-MOP: 合成 synthesis, dna互动 DNA interaction, 和抗增殖活性。 and antiproliferative activity.
已发布 PubMed:非侵袭性测定puva患者唾液中5-甲氧基补骨脂素和8-甲氧基补骨脂素 Measurement of 5-methoxypsoralen and 8-methoxypsoralen in saliva of PUVA patients as a noninvasive, 临床上与血液监测有关的替代方法。 clinically relevant alternative to monitoring in blood.
已发布 PubMed:[由毛状芸苔引起的大的光毒性接触性皮炎。 (花园街) [Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), 芸香科。病例报告和文献复习]。 Rutaceae. Case report and review of literature].
已发布 PubMed: 扫描电镜检查威士达 Wistar大鼠中补骨脂素引起的光性皮炎
已发布 PubMed:一组新颖的 有毒物质 A novel group of ovarian toxicants: 补骨脂素。 the psoralens.
已发布 PubMed:5-甲氧基补骨脂素。综述其在银屑病和白癜风中的作用。 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo.
已发布 PubMed:基于机制的失活由8-甲氧基补骨脂素和其他几种呋喃香豆素引起的细胞色素p450 2b1的失活。 Mechanism-based inactivation of cytochrome P450 2B1 by 8-methoxypsoralen and several other furanocoumarins.
已发布 PubMed:补骨脂素与季节性情感障碍有关。 Psoralens in association with seasonal affective disorder.
已发布 PubMed:芳香疗法油中的5-甲氧基补骨脂素产生光毒性接触性皮炎。 Phototoxic contact dermatitis from 5-methoxypsoralen in aromatherapy oil.
已发布 PubMed:呋喃香豆素基于机理的p450 2a6失活。 Mechanism-based inactivation of P450 2A6 by furanocoumarins.
已发布 PubMed:激发子处理诱导藤蔓香豆素细胞悬浮培养物中呋喃香豆素的生物合成。 Induction of furanocoumarin biosynthesis in Glehnia littoralis cell suspension cultures by elicitor treatment.
已发布 PubMed:uvr(a)bc核酸外切酶可识别三重 定向的补骨脂素交联键。 Triple helix-directed psoralen crosslinks are recognized by Uvr(A)BC excinuclease.
已发布 PubMed:puva诱导的nctc 2544角质形成细胞的细胞死亡 PUVA-induced cell mortality in NCTC 2544 keratinocytes: 它与补骨脂素激发态的微环境特性有关吗? is it related to the microenvironmental properties of the excited states of psoralens?
已发布 PubMed:5-甲氧基补骨脂素和5-甲氧基Angelicin的一些甲基衍生物的抗增殖活性和光毒性。 Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin.
已发布 PubMed:薄层色谱法测定患者血清中的5-甲氧基补骨脂素。 High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients.
已发布 PubMed:一些新的甲基-8-甲氧基补骨脂素 Some new methyl-8-methoxypsoralens: 合成 synthesis, 与dna光结合 photobinding to DNA, 光生物学特性和分子建模。 photobiological properties and molecular modelling.
已发布 PubMed:Bath-5甲氧基补骨脂素-Uva治疗牛皮癣。 Bath-5-methoxypsoralen-UVA therapy for psoriasis.
已发布 PubMed:cyp6b4的分离与表征 Isolation and characterization of CYP6B4, 来自多食性毛毛虫(鳞毛蕨)的呋喃香豆素诱导的细胞色素p450 a furanocoumarin-inducible cytochrome P450 from a polyphagous caterpillar (Lepidoptera: 乳头科 papilionidae)。
已发布 PubMed:两种天然呋喃酮的光生物活性研究 Studies on the photobiological activity of two naturally occurring furochromones, 维斯纳金和凯琳 visnagin and khellin, 在莱茵衣藻中。 in Chlamydomonas reinhardtii.
已发布 PubMed:荧光光谱 Spectrofluorimetric 判定 determination of 5-methoxypsoralen 药代动力学 pharmacokinetic in 耐心 患者 patients' 血清 serum.
已发布 PubMed: 补骨脂素诱导的威士达 wistar大鼠生长受到抑制。
已发布 PubMed:Warangalone和稳健酸对环amp依赖性蛋白激酶的特异性抑制。 Specific inhibition of cyclic AMP-dependent protein kinase by warangalone and robustic acid.
已发布 PubMed:呋喃香豆素诱导的黑素生成对小鼠表皮体内dna光损伤的保护作用。 Photoprotection by furocoumarin-induced melanogenesis against DNA photodamage in mouse epidermis in vivo.
已发布 PubMed:局部或口服白头翁提取物可预防急性晒伤和补骨脂素引起的光毒性反应以及 体皮肤中朗格汉斯细胞的消耗。 Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin.
已发布 PubMed:补骨脂素在 的整个皮肤和表皮上的极性均经过皮肤渗透(体外研究)。 Psoralens percutaneous permeation across the human whole skin and the epidermis in respect to their polarity (in vitro study).
已发布 PubMed:欧芹中抗菌素呋喃香豆素的分离与鉴定。 Isolation and identification of antimicrobial furocoumarins from parsley.
已发布 PubMed: 紫菜菌核和ammi majus种子的联合摄入所产生的猪的麦角病和光敏性。
已发布 PubMed:4'-Methyl 衍生品 derivatives of 5-MOP and 5-MOA: 合成 synthesis, 光反应性 photoreactivity, 和光生物学活性。 and photobiological activity.
已发布 PubMed:蒲引起的大疱性皮炎(燃烧的灌木丛)。 [Dermatitis bullosa striata pratensis caused by Dictamnus albus L. (burning bush)].
已发布 PubMed:干扰素α-2a联合阿维A或布瓦治疗低级皮肤T细胞淋巴瘤期间抗干扰素抗体的发病率和体内相关性。 Incidence and in-vivo relevance of anti-interferon antibodies during treatment of low-grade cutaneous T-cell lymphomas with interferon alpha-2a combined with acitretin or PUVA.
已发布 PubMed:与cd4 + t淋巴细胞减少相关的光增高的红皮病 Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: 5-甲氧基补骨脂素和uva成功治疗 successful treatment with 5-methoxypsoralen and UVA, 干扰素α-2b interferon alfa-2b, 和体外光采。 and extracorporeal photopheresis.
已发布 PubMed:蝇微粒体中的cyp6d1抑制剂。 Inhibitors of CYP6D1 in house fly microsomes.
已发布 PubMed:puva(5-甲氧基补骨脂素加uva)增强黑素生成并调节培养的黑素细胞中黑素生成蛋白的表达。 PUVA (5-methoxypsoralen plus UVA) enhances melanogenesis and modulates expression of melanogenic proteins in cultured melanocytes.
已发布 PubMed:抑制5-甲氧基补骨脂素对牛皮癣患者的咖啡因代谢。 Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis.
已发布 PubMed:通过溶解度和分配来确定用于治疗的补骨脂素的亲脂性 Lipophilicity determination of psoralens used in therapy through solubility and partitioning: 理论和实验方法的比较。 comparison of theoretical and experimental approaches.
已发布 PubMed:在鸡皮试验中,异海西平不具有光毒性。 Isopimpinellin is not phototoxic in a chick skin assay.
已发布 PubMed:5-甲氧基补骨脂素与胸腺嘧啶的光反应以及分离的酿酒酵母和脱氧核糖核酸酵母中的胸腺嘧啶部分。两个顺式呋喃侧单环加合物的表征和测量。 Photoreaction of 5-methoxypsoralen with thymidine and the thymine moiety of isolated and Saccharomyces cerevisiae DNA. Characterization and measurement of the two cis-syn furan-side monocycloadducts.
已发布 PubMed:5-甲氧基补骨脂素光加合物的形成 5-Methoxypsoralen photoadduct formation: 单加合物转化为交联。 conversion of monoadducts to crosslinks.
已发布 PubMed:黑素瘤和防晒霜的使用 Melanoma and use of sunscreens: 德国的eortc病例对照研究 an Eortc case-control study in Germany, 比利时和法国。 eortc黑素瘤合作组织。 Belgium and France. The EORTC Melanoma Cooperative Group.
已发布 PubMed:紫外线a诱导的5-甲氧基补骨脂素的光降解 Ultraviolet A-induced photodegradation of 5-methoxypsoralen, 8-甲氧基补骨脂素和补骨脂素在体内降低了呋喃香豆素的生物有效性。 8-methoxypsoralen and psoralen reduces the biological effectiveness of the furocoumarins in vivo.
已发布 PubMed:5-甲氧基补骨脂素与胸苷的光反应。嘧啶甲基的吡喃酮侧一加合物的分离和表征。 Photoreaction of 5-methoxypsoralen with thymidine. Isolation and characterization of a pyrone-side monoadduct involving the pyrimidine methyl group.
已发布 PubMed:5-甲氧基补骨脂素的抗抑郁作用 Antidepressant effect of 5-methoxypsoralen: 褪黑素同步器假说。 The melatonin synchronizer hypothesis.
已发布 PubMed: 获得了持久性非典型扁豆 lentigines,因为含5-甲氧基补骨脂素的防晒霜在光化学保护中不受紫外线 诱导的破坏。
已发布 PubMed:5-甲氧基补骨脂素抑制大鼠褪黑激素的6-羟基化。 5-Methoxypsoralen inhibits 6-hydroxylation of melatonin in the rat.
已发布 PubMed:甲氧补骨脂素对移行细胞癌的光疗。 Methoxypsoralen phototherapy of transitional cell carcinoma.
已发布 PubMed:潜在的化感化学物质及其对萝卜种子的作用。 Potential allelochemicals fromRuta graveolens L. and their action on radish seeds.
已发布 PubMed:5-甲氧基补骨脂素对 皮肤的uvr引起的dna损伤的发生时间和持续时间。 The time of onset and duration of 5-methoxypsoralen photochemoprotection from UVR-induced DNA damage in human skin.
已发布 PubMed:补骨脂素和紫外线治疗牛皮癣a。 8-甲氧基补骨脂素和5-甲氧基补骨脂素的双盲比较。 Treatment of psoriasis with psoralens and ultraviolet A. A double-blind comparison of 8-methoxypsoralen and 5-methoxypsoralen.
已发布 PubMed:酿酒酵母中各种dna破坏剂对rad54和rnr2基因的诱导。 Induction of the genes RAD54 and RNR2 by various DNA damaging agents in Saccharomyces cerevisiae.
已发布 PubMed:经puva处理的 类淋巴细胞中的染色体损伤与活性氧和致胶化因子有关。 Chromosome damage in PUVA-treated human lymphocytes is related to active oxygen species and clastogenic factors.
已发布 PubMed:乳头多烯cyp6b1基因的转录调控。 Transcriptional regulation of the Papilio polyxenes CYP6B1 gene.
已发布 PubMed:补体激活测定 The complement activation assay: 立即进行光毒性测试。 The test for immediate phototoxicity.
已发布 PubMed:[年代生物学和抑郁症 [Chronobiology and depression: 季节性萧条。临床方面 the seasonal depressions. Clinical aspects, 生理病理学和浸膏治疗方法]。 physiopathology and specific treatments].
已发布 PubMed:补骨脂素的作用方式 Mode of action of psoralens, 苯并呋喃 benzofurans, cri啶酮 acridinons, 和香豆素对完整髓鞘橙花纤维中离子电流的影响及其在脱髓鞘疾病中的意义。 and coumarins on the ionic currents in intact myelinated nerve fibres and its significance in demyelinating diseases.
已发布 PubMed:-5-甲氧基补骨脂素在没有紫外线的情况下对小鼠黑素瘤细胞中黑素生成的调节。 Regulation of melanogenesis induced by 5-methoxypsoralen without ultraviolet light in murine melanoma cells.
已发布 PubMed:局部呋喃香豆素和紫外线 治疗的c3h / tif hr / hr小鼠中表皮黑素生成的定量评估。 Quantitative assessment of epidermal melanogenesis in C3H/Tif hr/hr mice treated with topical furocoumarins and UVA radiation.
已发布 PubMed:气相色谱快速鉴定散装柑橘皮油中的某些香豆素衍生物 Rapid identification of some coumarin derivatives in deterpenated citrus peel oil by gas chromatography.
已发布 PubMed:新补骨脂素的作用 Effects of a new psoralen, 5杰拉诺木草素 5-geranoxypsoralen, 加上uva 对小鼠atpase阳性朗格汉斯 Langerhans细胞的影响。
已发布 PubMed:通过晒斑细胞计数测量佛手柑油光毒性的作用谱。 Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.
已发布 PubMed:英国光皮肤病学小组治疗湿疹的指南。 British Photodermatology Group guidelines for PUVA.
已发布 PubMed:新型微粒化的5-甲氧基补骨脂素片和紫外线 治疗牛皮癣。 Treatment of psoriasis with a new micronized 5-methoxypsoralen tablet and UVA radiation.
已发布 PubMed:食物引起的5-甲氧基补骨脂素生物利用度增加。 Food-induced increase in bioavailability of 5-methoxypsoralen.
已发布 PubMed:啤酒酵母中5-甲氧基补骨脂素诱导细胞色素p-450的表达。 Induction of cytochrome P-450 by 5-methoxypsoralen in the yeast Saccharomyces cerevisiae.
已发布 PubMed:5-甲氧基补骨脂素吡喃侧单环加合物与胸苷的顺式-顺式和反式-非对映异构体的表征。 Characterization of the cis-syn and cis-anti diastereoisomers of 5-methoxypsoralen pyrone-side monocycloadducts to thymidine.
已发布 PubMed:uva 与补骨脂素或当归素联用激活 免疫缺陷 启动子。 Activation of the human immunodeficiency virus promoter by UVA radiation in combination with psoralens or angelicins.
已发布 PubMed:堵塞淋巴结中的钾通道达4个 Blocking of potassium channels in Ranvier nodes by 4,5,6,7-取代的苯并呋喃及其对脱髓鞘疾病的意义。 7-substituted benzofurans and its significance on demyelinating diseases.
已发布 PubMed:[补骨脂素的长期作用?]。 [Long-term effect of psoralens?].
已发布 PubMed:小鼠和 肝微粒体中香豆素7-羟化酶活性的差异抑制。 Differential inhibition of coumarin 7-hydroxylase activity in mouse and human liver microsomes.
已发布 PubMed:体内紫外线辐照 体皮肤中的dna损伤 DNA damage in UV-irradiated human skin in vivo: 通过图像分析(胸腺嘧啶二聚体)进行的自动直接测量与间接测量(计划外的dna合成)进行比较,并通过5-甲氧基补骨脂素进行保护。 automated direct measurement by image analysis (thymine dimers) compared with indirect measurement (unscheduled DNA synthesis) and protection by 5-methoxypsoralen.
已发布 PubMed:皮肤上的8-甲氧基补骨脂素浓度 Skin concentration of 8-methoxypsoralen, 5-甲氧基补骨脂素和4 5-methoxypsoralen and 4,5,豚鼠中的8-三甲基补骨脂素。 8-trimethylpsoralen in guinea pigs.
已发布 PubMed:健康和牛皮癣中的无血清5-甲氧基补骨脂素部分 Serum free 5-methoxypsoralen fraction in health and psoriasis: 与 血清白蛋白浓度的关系。 relationship with human serum albumin concentration.
已发布 PubMed:千胡香豆素a的分离与结构解析。 [Isolation and structure elucidation of qianhucoumarin A].
已发布 PubMed:5-Methoxypsoralen: 对睡眠不足者的去甲肾上腺素昼夜节律的影响。 effect on the noradrenaline circadian rhythm of sleep-deprived subjects.
已发布 PubMed:晒黑制剂中使用光敏剂相关的光毒性和光遗传毒性风险评估 Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: 应用于含有佛手柑油的鞣制制剂。 application to tanning preparations containing bergamot oil.
已发布 PubMed:5-甲氧基补骨脂素与血液组分的结合。白蛋白和游离脂肪酸影响 Binding of 5-methoxypsoralen to blood fractions. Influence of albumin and free fatty acids: 体外研究。 an in vitro study.
已发布 PubMed:补骨脂素与dna的光结合的序列特异性 Sequence specificity of psoralen photobinding to DNA: 定量方法。 a quantitative approach.
已发布 PubMed:抗银屑病药物5-甲氧基补骨脂素在 体内的代谢 Metabolism of the anti-psoriatic agent 5-methoxypsoralen in humans: 与大鼠和狗的比较。 comparison with rat and dog.
已发布 PubMed:不同化学处理后酵母中细胞色素p450的表达 Expression of cytochrome P450 in yeast after different chemical treatments.
已发布 PubMed:8拖vs 5拖。 8-MOP vs 5-MOP.
已发布 PubMed:补骨脂素在紫外线照射下裂解pbr322 dna。 Psoralens cleave pBR322 DNA under ultraviolet radiation.
已发布 PubMed:8拖vs 5拖。 8-MOP vs 5-MOP.
已发布 PubMed:对5-甲氧基补骨脂素在牛皮癣治疗中的使用的重新评估。 A reappraisal of the use of 5-methoxypsoralen in the therapy of psoriasis.
已发布 PubMed:补骨脂素和uva(puva)光化学疗法的发展 The evolution of photochemotherapy with psoralens and UVA (PUVA): 公元前2000年至1992年广告。 2000 BC to 1992 AD.
已发布 PubMed:全身光化学疗法中使用的光毒性药物对肝脏转氨酶的影响。 The effect on liver transaminases of phototoxic drugs used in systemic photochemotherapy.
已发布 PubMed:8-甲氧基补骨脂素(8扑扑)和5扑扑的液体制剂 Liquid formulations of 8-methoxypsoralen (8-MOP) and 5-MOP: 急性非光毒性不良反应的前瞻性双盲交叉评估。 a prospective double-blind crossover assessment of acute non-phototoxic adverse effects.
已发布 PubMed:白三烯b4的转化和降解 Transformation and degradation of leukotriene B4, 紫外线诱导的12-羟基二十碳四烯酸和5-羟基二十碳四烯酸。 12-hydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid induced by ultraviolet radiation.
已发布 PubMed:绝经后骨质疏松症与松果体功能有关吗? Is postmenopausal osteoporosis related to pineal gland functions?
已发布 PubMed: [Lesbouriella seseloides wolff的化学成分]。
已发布 PubMed:一种新的微粉化的5-甲氧基补骨脂素制剂。更高的生物利用度和更低的uva剂量要求。 A new micronized 5-methoxypsoralen preparation. Higher bioavailability and lower UVA dose requirement.
已发布 PubMed:通过竞争性酶联免疫吸附法定量测定8-甲氧基补骨脂素的血浆水平。 Quantitation of plasma levels of 8-methoxypsoralen by competitive enzyme-linked immunosorbent assay.
已发布 PubMed:紫外线引起的dna损伤对 类的光保护和5拖把光化学保护 Photoprotection and 5-MOP photochemoprotection from UVR-induced DNA damage in humans: 皮肤类型的作用。 the role of skin type.
已发布 PubMed:酿酒酵母代谢5-甲氧基补骨脂素。 Metabolism of 5-methoxypsoralen by Saccharomyces cerevisiae.
已发布 PubMed:各种光毒性药物给药后皮肤浓度的研究。 Study of the skin concentrations after administration of the various phototoxic drugs.
已发布 PubMed:5-甲氧基补骨脂素可提高雄性大鼠血浆褪黑激素浓度 5-Methoxypsoralen enhances plasma melatonin concentrations in the male rat: 非去甲肾上腺素介导的刺激,在松果体切除动物中没有作用。 non-noradrenergic-mediated stimulation and lack of effect in pinealectomized animals.
已发布 PubMed:饮食和 类光毒性呋喃香豆素的风险评估。 Dietary intake and risk assessment of phototoxic furocoumarins in humans.
已发布 PubMed:口服5-甲氧基补骨脂素治疗白癜风。 Treatment of vitiligo with oral 5-methoxypsoralen.
已发布 PubMed:5-甲氧基补骨脂素和8-甲氧基补骨脂素与红细胞幽灵的黑暗相互作用 Dark interaction of 5-methoxypsoralen and 8-methoxypsoralen with erythrocyte ghosts: 荧光和圆二色性研究。 a fluorescence and circular dichroism study.
已发布 PubMed:简单平衡透析-高效液相色谱法体外评估 白蛋白结合的5-甲氧基补骨脂素。 Simple equilibrium dialysis-high-performance liquid chromatographic method for the in vitro assessment of 5-methoxypsoralen bound to human albumin.
已发布 PubMed:高效液相色谱法测定 体使用太阳能产品后吸水泡状液中的柠檬酸和香柠檬素 High-performance liquid chromatographic determination of citropten and bergapten in suction blister fluid after solar product application in humans.
已发布 PubMed:由于车皮鞭毛虫的光毒性。 Phototoxicity due to Cachrys libanotis.
已发布 PubMed:补骨脂素的作用机制 Mechanism of action of psoralens: 等效线图分析显示,补骨脂素作用的紫外线增强不是加成的,而是协同的。 isobologram analysis reveals that ultraviolet light potentiation of psoralen action is not additive but synergistic.
已发布 PubMed:峰起泡点 Peak blistering point: 全身给药后对 皮肤中5扑扑液体水平的影响 influence on fluid levels of 5-MOP in human skin in vivo after systemic administration.
已发布 PubMed:在 类中使用太阳能产品后,柠檬香柠檬素和Bergapten吸泡水的浓度。 Citropten and bergapten suction blister fluid concentrations after solar product application in man.
已发布 PubMed:使用表面恢复技术评估 体内5-甲氧基补骨脂素的经皮吸收。 Use of a surface recovery technique to evaluate percutaneous absorption of 5-methoxypsoralen in humans.
已发布 PubMed:高效液相色谱法分析8-甲氧基补骨脂素 Analysis of 8-methoxypsoralen by high-performance liquid chromatography.
已发布 PubMed:含有佛手柑油的香水对 体皮肤的光毒性 Phototoxic properties of perfumes containing bergamot oil on human skin: uva和uvb防晒霜的光保护作用。 photoprotective effect of UVA and UVB sunscreens.
已发布 PubMed:佛手油中5-甲氧基补骨脂素的光致肿瘤作用研究 Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: 苦参小鼠皮肤模型中 类使用风险的评估和修改。 evaluation and modification of risk of human use in an albino mouse skin model.
已发布 PubMed:酿酒酵母中佛手柑油和佛手柑油的遗传毒性。 Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae.
已发布 PubMed:躁郁症患者无反应性与松果体钙化之间的关系。 The relationship between ECT nonresponsiveness and calcification of the pineal gland in bipolar patients.
已发布 PubMed:芹菜摄入后严重的光毒性烧伤。 Severe phototoxic burn following celery ingestion.
已发布 PubMed:在没有紫外线的情况下,补骨脂素刺激小鼠黑素细胞和黑素瘤酪氨酸酶活性。 Psoralens stimulate mouse melanocyte and melanoma tyrosinase activity in the absence of ultraviolet light.
已发布 PubMed:5-甲氧基补骨脂素作为 类褪黑激素分泌的特定刺激剂。 5-Methoxypsoralen as a specific stimulating agent of melatonin secretion in humans.
已发布 PubMed:修复呋喃香豆素加uva引起的真核细胞损伤和诱变后果。 Repair of furocoumarin-plus-UVA-induced damage and mutagenic consequences in eukaryotic cells.
已发布 PubMed:晒黑还是不晒黑。 To tan or not to tan.
已发布 PubMed:局部5-甲氧基补骨脂素对紫外线照射在苦参和有色无毛小鼠皮肤中诱导的肿瘤发生的作用。 Effect on topical 5-methoxypsoralen on tumorigenesis induced in albino and pigmented hairless mouse skin by UV irradiation.
已发布 PubMed: 吡啶补骨脂素 psoralens光敏的环丁烷胸腺嘧啶二聚体的形成 : 三重态-三重态能量传递机制。 a triplet-triplet energy transfer mechanism.
已发布 PubMed:[由5拖把引起的光电解术(牛皮癣)及药物效应的插补方法的应用]。 [Photo-onycholysis caused by 5-MOP (Psoraderm) and the application of the imputation method of drug effects].
已发布 PubMed: 5拖把诱导的抗 皮肤紫外线 引起的表皮脱氧核糖核酸 DNA损伤保护作用。
已发布 PubMed:5-甲氧基补骨脂素的时间药代动力学。 Chronopharmacokinetics of 5-methoxypsoralen.
已发布 PubMed:桔梗的生长阶段和呋喃香豆素含量。 Heracleum mantegazzianum growth phases and furocoumarin content.
已发布 PubMed: 3-碳乙氧基补骨脂素 3-carbethoxypsoralen和其他呋喃香豆素光诱导的氧化性dna损伤。修复酶进行光氧化和识别的机理。
已发布 PubMed:晒黑还是不晒黑。一个亟待解决的问题。 To tan or not to tan. A burning question.
已发布 PubMed:呋喃香豆素对大鼠肝脏微粒体氧化的影响 [The effect of furanocoumarins on microsomal oxidation in the rat liver].
已发布 PubMed:佛手柑和阳光对皮肤色素沉着的影响。 The effects of bergapten and sunlight on cutaneous pigmentation.
已发布 PubMed:痴呆患者对5-甲氧基补骨脂素的褪黑素反应异常。 Abnormal melatonin response to 5-methoxypsoralen in dementia.
已发布 PubMed:分子力学探讨了补骨脂素在dna中的嵌入几何。 Geometry of intercalation of psoralens in DNA approached by molecular mechanics.
已发布 PubMed:当归活性成分对脂肪细胞脂质代谢的影响 Effects of active compounds isolated from Angelica shikokiana on lipid metabolism in fat cells.
已发布 PubMed:芸香芸苔的抗生育原则。 Antifertility principle of Ruta graveolens.
已发布 PubMed:全身光化学疗法诱发的黑素病。 Melanonychia induced by systemic photochemotherapy.
已发布 PubMed:5-甲氧基补骨脂素增加 的夜间嗜睡 5-Methoxypsoralen increases evening sleepiness in humans: 可能与褪黑激素分泌有关。 possible involvement of the melatonin secretion.
已发布 PubMed:5-甲氧基补骨脂素可增加视网膜对 类光线的敏感性。 5-Methoxypsoralen increases the sensitivity of the retina to light in humans.
已发布 PubMed:如前噬菌体诱导所显示的,三氢嘧啶具有光诱导的遗传毒性的进一步证据。 Further evidence for photoinduced genotoxicity of dictamnine as shown by prophage induction.
已发布 PubMed:5-甲氧基补骨脂素和8-甲氧基补骨脂素对β-环糊精的相对亲和力 Relative affinity of 5-methoxypsoralen and 8-methoxypsoralen towards beta-cyclodextrin: 荧光 a fluorescence, 圆二色性和色谱研究。 circular dichroism and chromatographic study.
已发布 PubMed:双功能呋喃香豆素处理后,通过羟磷灰石色谱测量的v-79中国仓鼠细胞中dna链间交联的诱导和去除。 Induction and removal of DNA interstrand cross-links in V-79 Chinese hamster cells measured by hydroxylapatite chromatography after treatments with bifunctional furocoumarins.
已发布 PubMed: 补骨脂素的生物合成。激发子处理过的ammi majus细胞的补骨脂素5-单加氧酶活性。
已发布 PubMed:5-甲氧基补骨脂素在二恶烷-水混合物中的光物理行为。 Photophysical behaviour of 5-methoxypsoralen in dioxane-water mixtures.
已发布 PubMed:光疗 Phototherapeutic, 光生物学的 photobiologic, 和凯灵蛋白的光敏特性。 and photosensitizing properties of khellin.
已发布 PubMed:补骨脂素衍生物与dna光反应的序列特异性 Sequence specificity in photoreaction of various psoralen derivatives with DNA: 在生物活性中的作用。 role in biological activity.
已发布 PubMed:5-甲氧基补骨脂素(bergapten)用于光化学疗法。生物利用度 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, 光毒性 phototoxicity, 牛皮癣的新药制备及临床疗效。 and clinical efficacy in psoriasis of a new drug preparation.
已发布 PubMed:细胞核吸收8-甲氧基补骨脂素和5-甲氧基补骨脂素的证据。 Evidence for uptake of 8-methoxypsoralen and 5-methoxypsoralen by cellular nuclei.
已发布 PubMed:5-甲氧基补骨脂素棕褐色在 皮肤中抑制紫外线 引起的dna损伤。 Inhibition of UV radiation-induced DNA damage by a 5-methoxypsoralen tan in human skin.
已发布 PubMed:5-甲氧基补骨脂素的抗抑郁作用 Antidepressant effect of 5-methoxypsoralen: 初步报告。 a preliminary report.
已发布 PubMed:生物制药 Biopharmaceutics, 补骨脂素的药代动力学和药理学。 pharmacokinetics and pharmacology of psoralens.
已发布 PubMed: 紫外线 紫外线 UVB防晒霜对5-甲氧基补骨脂素光致癌作用的修饰 : 对无毛苦参小鼠的统计和组织学研究。 a statistical and histologic study in the hairless albino mouse.
已发布 PubMed:5-甲氧基补骨脂素 5-Methoxy psoralen, 抗坏血酸 etretinate, 和尿素用于牛皮癣。 and UVA for psoriasis.
已发布 PubMed:豚鼠血清中8-甲氧基补骨脂素和5-甲氧基补骨脂素分布的动力学 Kinetics of 8-methoxypsoralen and 5-methoxypsoralen distribution in guinea pig serum, 表皮和眼晶状体。 epidermis and ocular lens.
已发布 PubMed:5-甲氧基补骨脂素作为荧光探针的dna内部疏水性指数估算。 Estimation of an index of hydrophobicity of DNA interior using 5-methoxypsoralen as a fluorescent probe.
已发布 PubMed:5-甲氧基补骨脂素可增加 体血浆褪黑激素水平。 5-Methoxypsoralen increases the plasma melatonin levels in humans.
已发布 PubMed:8-甲氧基补骨脂素的毒性 Toxicity of 8-methoxypsoralen, 5-methoxypsoralen, 3-碳乙氧基补骨脂素 3-carbethoxypsoralen, 或5-甲基异补骨脂素在无毛(hra / skh)小鼠中受到紫外线 。 or 5-methylisopsoralen with ultraviolet radiation in the hairless (HRA/Skh) mouse.
已发布 PubMed:5-甲氧基补骨脂素加uv-a对 淋巴细胞的体外杀灭作用,以及抗虫原β-氨基乙基异硫脲的修饰作用。 The clastogenic effect of 5-methoxypsoralen plus UV-A in human lymphocytes in vitro and its modification by the anticlastogen beta-aminoethylisothiouronium.
已发布 PubMed:甲氧沙林和其他补骨脂素衍生物灭活 肝细胞色素p-450。 Inactivation of human liver cytochrome P-450 by the drug methoxsalen and other psoralen derivatives.
已发布 PubMed:5-甲氧基补骨脂素和8-甲氧基补骨脂素加uv-a在 淋巴细胞中引起的染色体损伤。 Chromosome damage induced in human lymphocytes by 5-methoxypsoralen and 8-methoxypsoralen plus UV-A.
已发布 PubMed:补骨脂素增强紫外线诱导的表皮生长因子结合的抑制作用。 Psoralens potentiate ultraviolet light-induced inhibition of epidermal growth factor binding.
已发布 PubMed:5-甲氧基补骨脂素单加合物修饰的芳香四肽和dna之间的暗相互作用和氧依赖性光结合。 Dark interaction and oxygen dependent photobinding between an aromatic tetrapeptide and DNA modified by 5-methoxypsoralen monoadducts.
已发布 PubMed: 在hra / skh无毛小鼠中使用各种补骨脂素衍生物和紫外线 UV-a(uva) ​​治疗的视觉效果。
已发布 PubMed:皮肤光毒性反应。 Cutaneous phototoxicity reactions.
已发布 PubMed:各种补骨脂素衍生物对大鼠细胞色素p-450的失活和诱导作用。 Inactivation and induction of cytochrome P-450 by various psoralen derivatives in rats.
已发布 PubMed:[光敏剂在皮肤病学中的治疗用途提出的问题]。 [Problems posed by the therapeutic use of photosensitizers in dermatology].
已发布 PubMed:使用dna修复缺陷型细菌的超灵敏生物光检测法检测植物和植物产品中的呋喃香豆素。 Detection of furocoumarins in plants and plant products with an ultrasensitive biological photoassay employing a DNA-repair-deficient bacterium.
已发布 PubMed:5-甲氧基补骨脂素和8-甲氧基补骨脂素的一些水溶性衍生物的遗传毒性。 Genotoxic activity of some water-soluble derivatives of 5-methoxypsoralen and 8-methoxypsoralen.
已发布 PubMed:牛皮癣患者使用安替比林测试来测试肝脏的单加氧酶系统 [Testing the monooxygenase enzyme system of the liver using the antipyrine test in psoriasis patients].
已发布 PubMed:呋喃香豆素在真核细胞中光诱导的脱氧核糖核酸单和二加合物的遗传效应。 Genetic effects of DNA mono- and diadducts photoinduced by furocoumarins in eukaryotic cells.
已发布 PubMed:甲氧沙林和其他补骨脂素的临床药代动力学。 Clinical pharmacokinetics of methoxsalen and other psoralens.
已发布 PubMed:5-甲氧基补骨脂素。 5-Methoxypsoralen.
已发布 PubMed:各种补骨脂素衍生物诱导 细胞中的dna-dna交联形成。 Induction of DNA-DNA cross-link formation in human cells by various psoralen derivatives.
已发布 PubMed:5-甲氧基补骨脂素和8-甲氧基补骨脂素在中国仓鼠v79细胞中的遗传毒性作用和dna光加合物。 Genotoxic effects and DNA photoadducts induced in Chinese hamster V79 cells by 5-methoxypsoralen and 8-methoxypsoralen.
已发布 PubMed:单功能和双功能呋喃香豆素在dna中光诱导的损伤与二倍体酵母的遗传毒性作用之间的关系。 Relationship between lesions photoinduced by mono- and bi-functional furocoumarins in DNA and genotoxic effects in diploid yeast.
已发布 PubMed:一些水溶性5拖和8拖衍生物的光生物学特性。 Photobiological properties of some water-soluble 5-MOP and 8-MOP derivatives.
已发布 PubMed:欧芹中香菜碱含量及其在引起皮肤光敏性中的意义。 The bergapten content of garden parsley and its significance in causing cutaneous photosensitization.
已发布 PubMed:[精油中的呋喃香豆素。制品中5-甲氧基补骨脂素的鉴定与测定] [Furocoumarins in essential oils. Identification and determination of 5-methoxypsoralen in sun products].
已发布 PubMed:对患病芹菜的光敏反应的机理。 Mechanism of photosensitivity reactions to diseased celery.
已发布 PubMed:比较两种5-甲氧基补骨脂素口服制剂的生物利用度和光毒性。 Comparison of bioavailability and phototoxicity of two oral preparations of 5-methoxypsoralen.
已发布 PubMed:念珠菌的光毒性测试。不同菌株和念珠菌种的敏感性 The Candida phototoxicity test. The sensitivity of different strains and species of Candida, 标准化尝试和对5-甲氧基补骨脂素和8-甲氧基补骨脂素的剂量反应曲线的分析。 standardization attempts and analysis of the dose-response curves for 5- and 8-methoxypsoralen.
已发布 PubMed:防晒化妆品中5-甲氧基补骨脂素的测定 [Determination of 5-methoxypsoralen in suntan cosmetics].
已发布 PubMed:使用吡啶并补骨脂素的光化学疗法。 Photochemotherapy using pyridopsoralens.
已发布 PubMed:补骨脂素-核酸光加合物的化学结构。 Chemical structure of psoralen-nucleic acid photoadducts.
已发布 PubMed:柠檬油的光毒性研究。 A study of the phototoxicity of lemon oil.
已发布 PubMed:补骨脂素局部和全身反应性的差异 Difference in topical and systemic reactivity of psoralens: 表皮和血清水平的测定。 determinations of epidermal and serum levels.
已发布 PubMed:补骨脂素和紫外线a对无毛小鼠中表皮鸟氨酸脱羧酶的诱导和dna合成的影响。 Psoralen and ultraviolet A effects on epidermal ornithine decarboxylase induction and DNA synthesis in the hairless mouse.
已发布 PubMed:口服补骨脂素的药代动力学和药效学 Pharmacokinetics and pharmacodynamics of psoralens after oral administration: 注意事项和结论。 considerations and conclusions.
已发布 PubMed:四种补骨脂素衍生物与dna反应的体外表征。 In vitro characterization of the reaction of four psoralen derivatives with DNA.
已发布 PubMed:牛皮癣中所选补骨脂素的安全性和疗效。 Safety and therapeutic effectiveness of selected psoralens in psoriasis.
已发布 PubMed:补骨脂素诱导中国仓鼠 细胞的姐妹染色单体交换和基因突变。 Induction of sister chromatid exchanges and gene mutations in Chinese hamster ovary cells by psoralens.
已发布 PubMed:国家毒理学计划研究项目中使用的补骨脂素的化学表征。 Chemical characterization of psoralens used in the National Toxicology Program research projects.
已发布 PubMed: 合成一些具有潜在抗菌活性的佛手柑和ammajin ammajin衍生物。
已发布 PubMed:激光多普勒测速仪对紫外线引起的微循环流量变化进行定量评估。 Quantitative assessment of UV-induced changes in microcirculatory flow by laser Doppler velocimetry.
已发布 PubMed:[香豆素衍生物作为抗5-甲氧基补骨脂素和uv-a在莱茵衣藻中的细胞毒和诱变作用的保护剂]。 [Coumarin derivatives as protective agents against the cytotoxic and mutagenic effect of 5-methoxypsoralen and UV-A in Chlamydomonas reinhardii].
已发布 PubMed:无花果分离和定量光敏成分。 Ficus carica; isolation and quantification of the photoactive components.
已发布 PubMed:5-甲氧基补骨脂素与 血清低密度脂蛋白的结合。 Binding of 5-methoxypsoralen to human serum low density lipoproteins.
已发布 PubMed:黑暗中呋喃香豆素鼠 歐洲海濱草的移码致突变性。 Frameshift mutagenicity in Salmonella typhimurium of furocoumarins in the dark.
已发布 PubMed:补骨脂素和紫外线(320-400 nm)产生活性氧(1o2和o2-。)。 Production of active oxygen species (1O2 and O2-.) by psoralens and ultraviolet radiation (320-400 nm).
已发布 PubMed:无毛小鼠中含有补骨脂素的防晒霜具有致瘤性吗? Is psoralen-containing sunscreen tumorigenic in hairless mice?
已发布 PubMed:[由于5-或8-甲氧基补骨脂素和紫外线 导致多形核嗜中性粒细胞活力丧失]。 [Loss of vitality of polymorphonuclear neutrophilic granulocytes due to 5- or 8-methoxypsoralen and UV radiation].
已发布 PubMed:dna交联和单加合物形成补骨脂素和长波紫外线 诱导不同鼠 歐洲海濱草菌株中前噬菌体的表达。 The induction of prophage expression in different Salmonella typhimurium strains by DNA cross-linking and monoadduct forming psoralens and longwave ultraviolet radiation.
已发布 PubMed: uv-a过滤器抑制佛手柑 Bergaptene毒性。
已发布 PubMed:患有白癜风患者的乳糜中呋喃香豆素(补骨脂素)的光毒性。佛手柑的作用谱研究 Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, 匹品林 pimpinellin, 当归和斯潘丁 sphondin。
已发布 PubMed:乳草的光化学反应。二甲亚砜和皮质类固醇的影响。 Photochemical reactions of Heracleum laciniatum. Influence of dimethyl sulphoxide and corticosteroids.
已发布 PubMed:乳草的呋喃香豆素 Furocoumarins of Heracleum laciniatum: 隔离 isolation, 光毒性 phototoxicity, 吸收和作用谱研究。 absorption and action spectra studies.
已发布 PubMed:含有补骨脂素的防晒霜在无毛小鼠中具有致瘤性。 Psoralen-containing sunscreen is tumorigenic in hairless mice.
已发布 PubMed: 3-碳乙氧基补骨脂素 3-carbethoxypsoralen的一些光物理性质 , 8-甲氧基补骨脂素和5-甲氧基补骨脂素三重态。 8-methoxypsoralen and 5-methoxypsoralen triplet states.
已发布 PubMed:比较暴露于太阳模拟 的无毛苦参小鼠中8拖把和5拖把的光致肿瘤潜力。 A comparison of the phototumorigenic potential of 8-MOP and 5-MOP in hairless albino mice exposed to solar simulated radiation.
已发布 PubMed: pradianthos 三 triradiatus的呋喃香豆素组成。
已发布 PubMed:5的光生物活性 Photobiological activity of 5,7-二甲氧基香豆素。 7-dimethoxycoumarin.
已发布 PubMed:5-甲氧基补骨脂素对植物血凝素刺激的淋巴细胞体外转化率的影响 [Effect of 5-methoxypsoralen on the phytohemagglutinin-stimulated lymphocyte transformation rate in vitro].
已发布 PubMed:液相色谱-荧光光谱法定量测定血浆中5-甲氧基补骨脂素 [Quantitative determination of 5-methoxypsoralen in plasma by liquid chromatography and spectrofluorometric detection].
已发布 PubMed:角性补骨脂素衍生物引起的致命性淋巴细胞损伤 [Lethal lymphocyte damage caused by angular psoralen derivatives].
已发布 PubMed:无毛小鼠表皮中的晒伤细胞 The sunburn cell in hairless mouse epidermis: 紫外线 以及单功能和双功能补骨脂素的定量研究。 quantitative studies with UV-A radiation and mono- and bifunctional psoralens.
已发布 PubMed:防晒霜 Sunscreens: 保护 类皮肤免受太阳 有害影响的局部和全身方法。 topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
已发布 PubMed:补骨脂素的光毒性 Psoralen phototoxicity: 与豚鼠血清和表皮的8-甲氧基补骨脂素和5-甲氧基补骨脂素的相关性。 correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig.
已发布 PubMed:高效液相色谱法测定无花果叶香豆素成分 [Determination of the coumarinic constituents of Ficus carica leaves by HPLC].
已发布 PubMed:补骨脂素的比较光生物学。 Comparative photobiology of psoralens.
已发布 PubMed:含补骨脂素的防晒霜可诱导光毒性和表皮鸟氨酸脱羧酶活性。 Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
已发布 PubMed:5-甲氧基补骨脂素和近紫外光对大肠杆菌wp2缺乏修复菌株的遗传毒性。 Genotoxicity of 5-methoxypsoralen and near ultraviolet light in repair-deficient strains of Escherichia coli WP2.
已发布 PubMed:[5-甲氧基补骨脂素 [5-Methoxypsoralen: 生物利用度和药代动力学]。 bioavailability and pharmacokinetics].
已发布 PubMed:尾草履虫和梨形四膜虫细胞裂解法测定5-甲氧基补骨脂素和8-甲氧基补骨脂素的光敏能力的比较研究 Comparative studies on the photosensitizing potency of 5-methoxypsoralen and 8-methoxypsoralen as measured by cytolysis in Paramecium caudatum and Tetrahymena pyriformis, 和白念珠菌的生长抑制和存活。 and growth inhibition and survival in Candida albicans.
已发布 PubMed:防晒霜及其副作用。 Sunscreens and their side effects.
已发布 PubMed:仓鼠和 细胞(包括共济失调毛细血管扩张症和色素干性皮肤病患者的细胞)中的呋喃香豆素和uva引起的染色体损伤。 Chromosomal damage induced by furocoumarins and UVA in hamster and human cells including cells from patients with ataxia telangiectasia and xeroderma pigmentosum.
已发布 PubMed:禁止在晒黑制剂中使用佛手柑油的不适当规定。 Inappropriate regulations governing the use of oil of bergamot in suntan preparations.
已发布 PubMed:口服后5-甲氧基补骨脂素的血清和尿液浓度。 Serum and urine concentrations of 5-methoxypsoralen after oral administration.
已发布 PubMed:防晒霜及其副作用。 Sunscreens and their side effects.
已发布 PubMed:相高效液相色谱法测定血浆中甲氧沙林的含量 Analysis of methoxsalen in plasma by reversed-phase high-performance liquid chromatography.
已发布 PubMed:[Comparison of 光致突变的 photo诱变的 mutagenic 活动 activities of 5-mop (bergapten) and 8-mop (黄花毒素 xanthotoxin) in 衣藻 chlamydomonas 莱因哈迪 reinhardii (author's 翻译 transl)].
已发布 PubMed:皮肤疾病的光化学疗法 Photochemotherapy of skin-diseases: 各种单功能和双功能剂的光化学和光生物学特性的比较研究。 comparative studies on the photochemical and photobiological properties of various mono- and bifunctional agents.
已发布 PubMed:酵母中的三种单功能和三种双功能呋喃香豆素的诱变活性。 Mutagenic activity of three monofunctional and three bifunctional furocoumarins in yeast (Saccharomyces cerevisiae).
已发布 PubMed:[5-或8-甲氧基补骨脂素对 类培养的淋巴细胞的光敏作用]。 [Photosensitization effect of 5- or 8-methoxypsoralen on human cultured lymphocytes].
已发布 PubMed:伯罗克性皮炎-持续的美容问题。 Berloque dermatitis - a continuing cosmetic problem.
已发布 PubMed:防晒化妆品中佛手柑中含量的测定。 Determination of bergapten in suntan cosmetics.
已发布 PubMed:5-和8-甲氧基补骨脂素对cho细胞的光化学作用的比较。 A comparison of the photochemical actions of 5- and 8-methoxypsoralen on CHO cells.
已发布 PubMed:5-Methoxypsoralen, 晒黑制剂中的黑素添加剂 the melanogenic additive in sun-tan preparations, 在暴露于365 nm紫外线的小鼠中具有致瘤性。 。 is tumorigenic in mice exposed to 365 nm u.v. radiation.
已发布 PubMed:光化学疗法的临床方面。 Clinical aspects of photochemotherapy.
已发布 PubMed:液相色谱法测定吸水疱液和血清中的8-甲氧基补骨脂素。 Determination of 8-methoxypsoralen in suction-blister fluid and serum by liquid chromatography.
已发布 PubMed:呋喃香豆素与dna和蛋白质复合的脉冲放射分解研究。 A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins.
已发布 PubMed:晒黑制剂中与5-甲氧基补骨脂素有关的可能的癌症危害。 Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
已发布 PubMed:5-Methoxypsoralen, 几种晒黑制剂中的成分 an ingredient in several suntan preparations, 致命 has lethal, 诱变和致裂特性。 mutagenic and clastogenic properties.
已发布 PubMed:高效液相色谱法测定血清中抗凝乙酰香豆素的纳克水平。 Determination of nanogram levels of the anticoagulant acenocoumarin in serum by high-performance liquid chromatography.
已发布 PubMed:晒黑制剂中与5-甲氧基补骨脂素有关的可能的癌症危害。 Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
已发布 PubMed:晒黑制剂中与5-甲氧基补骨脂素有关的可能的癌症危害。 Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
已发布 PubMed:晒黑制剂中与5-甲氧基补骨脂素有关的可能的癌症危害。 Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
已发布 PubMed:一种测量表皮药物富集的快速方法。 A rapid method for measuring drug enrichment in epidermis.
已发布 PubMed:5-和8-甲氧基补骨脂素在体外与 血清蛋白(白蛋白)和表皮的可逆结合。 Reversible binding of 5- and 8-methoxypsoralen to human serum proteins (albumin) and to epidermis in vitro.
已发布 PubMed:晒黑制剂中与5-甲氧基补骨脂素有关的可能的癌症危害。 Possible cancer hazard associated with 5-methoxypsoralen in suntan preparations.
已发布 PubMed:5-甲氧基补骨脂素(bergapten)在牛皮癣的光化学疗法中。 5-Methoxypsoralen (Bergapten) in photochemotherapy of psoriasis.
已发布 PubMed:药物-蛋白质相互作用 Drug-protein interaction: 呋喃香豆素的血浆蛋白结合。 plasma protein binding of furocoumarins.
已发布 PubMed:百草枯的光毒性。 Phototoxicity of Dictamnus alba.
已发布 PubMed:研究佛手柑油及其作为光毒剂的重要性。 ii。影响佛手柑油和补骨脂素衍生物引起的光毒性反应的因素。 A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives.
已发布 PubMed:光化学疗法(脓)和牛皮癣 Photochemotherapy (PUVA) and psoriasis: 比较8拖把和8拖把/ 5拖把。 comparison of 8-MOP and 8-MOP/5-MOP.
已发布 PubMed:薄层色谱和分光光度法测定香料制品中的香柠檬素。 Determination of bergapten in fragrance preparations by thin layer chromatography and spectrophotofluorometry.
已发布 PubMed:菌核盘菌感染的芹菜中黄原毒素(8-甲氧基补骨脂素)和佛手柑(5-甲氧基补骨脂素)的分离和鉴定。 Isolation and identification of xanthotoxin (8-methoxypsoralen) and bergapten (5-methoxypsoralen) from celery infected with Sclerotinia sclerotiorum.
已发布 PubMed:[由于香菜碱引起的光皮病(芹菜收获工 的流行病的考虑)。 [Photodermatosis due to bergaptene (considerations apropos of an epidemic in workers occupied in the celery harvest)].
已发布 PubMed:芹菜和香菜中香菜碱含量的研究 [Research on the bergaptene content of celery and parsley].
已发布 PubMed:番荔枝叶片中补骨脂素和香菜碱含量的研究 [Research on the content of psoralen and bergaptene in the leaves of Ficus carica].
 
笔记 Notes:
主标题甲氧沙林是指8-甲氧基补骨脂素。主要组成。佛手柑油(柑橘佛手柑)。芹菜中 main heading methoxsalen refers to 8-methoxypsoralen. Major constit. of bergamot oil (Citrus bergamia). Present in celery, 尤其是外在的叶子 esp. the outer leaves, 和其他常见的杂货蔬菜。与杂货店工 的光性皮炎有关 and other common grocery vegetables. Implicated in photodermatitis among grocery workers
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