clotrimazole
二苯基-（2-氯苯基）-1-咪唑基甲烷 diphenyl-(2-chlorophenyl)-1-imidazolylmethane

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  23593-75-1克霉唑> 98％ 23593-75-1 Clotrimazole >98%
  克霉唑是合成的 Clotrimazole is a synthetic, 咪唑的抗真菌和广谱衍生物。它是一种常用于治疗真菌感染的抗真菌药物 antifungal and broad-spectrum derivate of imidazole. It is an antifungal medication commonly used in the treatment of fungal infections

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Name: 1-[（2-氯苯基）-二苯基甲基]咪唑 1-[(2-chlorophenyl)-diphenylmethyl]imidazole CAS号 CAS Number: 23593-75-1 3D/INCHI 其他 Other: 117829-71-7 FDA UNII: G07GZ97H65 nikkaji网站 Nikkaji Web: J3.156I 贝尔斯坦数 Beilstein Number: 0622318 MDL : mfcd00057220 MFCD00057220 XlogP3-AA: 5.00（est） 5.00 (est) 分子量 Molecular Weight: 344.84349000 式 Formula: c22 h17 cl n2 C22 H17 Cl N2 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:antidandruff, antimicrobial agents   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 学者 sch Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search PubMed: 搜索 Search NCBI: 搜索 Search   物理性质 Physical Properties: 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 熔点 Melting Point: 148.00 °C. @ 760.00 mm 汞 Hg 溶于 Soluble in:   水 water, 0.02984 mg / l @ 25°c（est） 0.02984 mg/L @ 25 °C (est)   感官特性 Organoleptic Properties: 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: CosIng: 化妆品数据 cosmetic data 化妆品用途 Cosmetic Uses: 去头皮屑剂 antidandruff agents antimicrobial agents   供应商 Suppliers: BOC Sciences 仅供实验/研究使用。 For experimental / research use only. 克霉唑> 98％ Clotrimazole >98% 气味 Odor: characteristic 采用 Use: 克霉唑是合成的 Clotrimazole is a synthetic, 咪唑的抗真菌和广谱衍生物。它是一种常用于治疗真菌感染的抗真菌药物 antifungal and broad-spectrum derivate of imidazole. It is an antifungal medication commonly used in the treatment of fungal infections Glentham Life Sciences Clotrimazole Penta International 克霉唑粉 CLOTRIMAZOLE POWDER USP 西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma 仅供实验/研究使用。 For experimental / research use only. Clotrimazole sds sds 环球防腐化学公司 Universal Preserv-A-Chem Inc. 克霉唑 CLOTRIMAZOLE 气味 Odor: characteristic 采用 Use: 克霉唑是一种咪唑类抗真菌药，对多种真菌形式均具有活性，对多种类型的真菌感染均有效。 Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections.   安全信息 Safety Information: 首选SDS Preferred SDS: 视图 View   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 口猫 口服 oral-cat LD50 > 1000 mg/kg GASTROINTESTINAL: 恶心 NAUSEA OR VOMITING Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 22, pg. 1272 Pg. 1272, 1972. 口头狗 口服 oral-dog LD50 > 2000 mg/kg GASTROINTESTINAL: 恶心 NAUSEA OR VOMITING Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 22, pg. 1272 Pg. 1272, 1972. 哺乳动物 口服 oral-mammal (种类 species 未指定 unspecified) LD50 750 mg/kg Antimicrobial 代理商 Agents and 化学疗法 Chemo治疗 therapy 卷 Vol. -, pg。 271 Pg. 271, 1969. 腹腔内小鼠 intraperitoneal-mouse LD50 108 mg/kg 药品 Drug and Chemical Toxicology. 卷 Vol. 13, pg。 195 Pg. 195, 1990. 静脉老鼠 intravenous-mouse LD50 198 mg/kg Gekkan 药师 Yakuji. 药品 Pharmaceuticals 每月一次 Monthly. 卷 Vol. 9, pg。 759 Pg. 759, 1967. 老鼠 口服 oral-mouse LD50 761 mg/kg Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 22, pg. 1272 Pg. 1272, 1972. 口服兔子 口服 oral-rabbit LD50 > 1000 mg/kg 行为的 BEHAVIORAL: 嗜睡（一般抑郁活动） SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) 行为的 BEHAVIORAL: 抽搐或对癫痫发作阈值的影响 CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD 行为的 BEHAVIORAL: 肌肉 MUSCLE WEAKNESS Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 22, pg. 1272 Pg. 1272, 1972. 腹膜内大鼠 intraperitoneal-rat LD50 445 mg/kg Kiso to 林修 Rinsho. 临床 Clinical 报告 Report. 卷 Vol. 7, pg. 1333 Pg. 1333, 1973. 口鼠 口服 oral-rat LD50 708 mg/kg Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 22, pg. 1272 Pg. 1272, 1972. 皮肤毒性 Dermal Toxicity: 皮下老鼠 sub皮肤的 cutaneous-mouse ldlo LDLo 10000 mg/kg Kiso to 林修 Rinsho. 临床 Clinical 报告 Report. 卷 Vol. 7, pg. 1333 Pg. 1333, 1973. 皮下大鼠 sub皮肤的 cutaneous-rat ldlo LDLo 10000 mg/kg Kiso to 林修 Rinsho. 临床 Clinical 报告 Report. 卷 Vol. 7, pg. 1333 Pg. 1333, 1973. 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: antidandruff, antimicrobial agents 克霉唑的使用建议水平最高为 Recommendation for clotrimazole usage levels up to:   不用于香水。 not for fragrance use.   克霉唑风味剂使用建议水平最高 Recommendation for clotrimazole flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: Epi系统 EPI System: 视图 View 临床 Clinicaltrials.gov :search 每日医学 Daily Med:search nlm NLM有害物质数据库 :搜索 Search 化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search 辅助引文 AIDS Citations:搜索 Search 癌症引文 Cancer Citations:搜索 Search 毒理学引文 Toxicology Citations:搜索 Search 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（SRS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :2812 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data sccnfp SCCNFP:意见 opinion 德国wgk WGK Germany:3 1-[（2-氯苯基）-二苯基甲基]咪唑 1-[(2-chlorophenyl)-diphenylmethyl]imidazole chemidplus Chemidplus:0023593751 技术 RTECS:用于cas＃23593-75-1的ni4377000 NI4377000 for cas# 23593-75-1   参考资料 References:   1-[（2-氯苯基）-二苯基甲基]咪唑 1-[(2-chlorophenyl)-diphenylmethyl]imidazole NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI 加拿大国内分公司。清单 Canada Domestic Sub. List: 23593-75-1 pubchem（cid） Pubchem (cid): 2812 pubchem（sid） Pubchem (sid): 134995329   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View 格尔姆代谢组数据库 Golm Metabolome Database: 搜索 Search KEGG (GenomeNet): C06922 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): HMDB01922 食物 FooDB: FDB022740 医药线 MedlinePlusSupp: 视图 View 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and core components note 没找到 None Found   潜在用途 Potential Uses: 没找到 None Found   存在（自然 Occurrence (nature, food, 其他） other):note   自然界中找不到 not found in nature   同义词 Synonyms:   bay 5097   湾 bay-B 5097   Canesten canesten   固体油烯 Canesten canestene   canifug 1-(o- chloro-alpha,α-二苯基苄基 α- alpha-联苯 diphenylbenzyl)咪唑 imidazole 1-((o- chloro-phenyl)二苯甲基 联苯 diphenylmethyl)咪唑 imidazole 1-[(2- chlorophenyl)-二苯甲基 -二苯甲基 联苯 diphenylmethyl]咪唑 imidazole 1-(α- alpha-(2- chlorophenyl)苯甲基 benzhydryl)咪唑 imidazole (2- chlorophenyl)联苯- 联苯 diphenyl-1-imidazolylmethane 1-((2- chlorophenyl)二苯甲基 联苯 diphenylmethyl)-1H-咪唑 imidazole 1-((2- chlorophenyl)二苯甲基 联苯 diphenylmethyl)-1H-咪唑 imidazole (9CI) 1-(o- chlorophenyl二苯甲基 联苯 diphenylmethyl)咪唑 imidazole ( 氯三苯甲基 chlorotrityl)咪唑 imidazole 1-(o- 氯三苯甲基 chlorotrityl)咪唑 imidazole   氯霉素 clomatin   克霉唑 clotrimazolum   可爱的 cutistad   脱氨 desamix F   二苯基-（2-氯苯基）-1-咪唑基甲烷 diphenyl-(2-chlorophenyl)-1-imidazolylmethane   联苯 diphenyl(2-chlorophenyl)(1-imidazolyl)methane   empecid bis- fenil-(2-clorofenil)-1-imidazolil-metano   吉洛胺 gino-lotremine   盖恩 gyne Lotrimin lotrimin   妇科肌醇 盖恩 gyne-Lotrimin lotrimin   妇科肌醇 盖恩 gyne-Lotrimin lotrimin 3   妇科肌醇 盖恩 gyne-Lotrimin lotrimin 3 组合 combination 包 pack   妇科肌醇 盖恩 gyne-Lotrimin lotrimin 组合 combination 包 pack   gynix 1H- 咪唑 imidazole, 1-((2-chlorophenyl)二苯甲基 联苯 diphenylmethyl)-   咪唑 imidazole, 1-（邻氯-α 1-(o-chloro-alpha,α-二苯基苄基 α- alpha-联苯 diphenylbenzyl)-   积德胜 jidesheng   Lotrimax lotrimax   Lotrimin lotrimin af AF   洛替松 lotrisone   methane, 双苯基 bis-phenyl-(2-chlorophenyl)-1-imidazolyl-   单贝肯 mono-baycuten   monobaycuten monobaycuten   脊髓 mycelex 7   脊髓 mycelex G   脊髓 mycelex 场外交易 OTC   脊髓 mycelex 锭 troches   脊髓 mycelex-7   脊髓 mycelex-7 组合 combination 包 pack   霉菌素 脊髓 mycelex-G   霉菌 mycofug   霉菌素 mycosporin   霉菌素 mykosporin   纳尔比克斯 nalbix   泛真菌 pan-fungex   pedisafe bis- phenyl-(2-chlorophenyl)(1-imidazoyl)methane bis phenyl-(2-chlorphenyl)-1-imidazolyl-methan bis phenyl-(2-chlorphenyl)-1-imidazolyl-methan [德语 German]   rimazole   替马唑 stiemazol   提巴汀 tibatin   Trimysten trimysten   曲戊唑 trivagizole 3   Veltrim veltrim   文章 Articles: PubMed:皇冠雏菊根分泌物中的月桂酸可有效调节根结 的趋化性，并破坏mi-flp-18的表达以阻止感染。 Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection. 阶段 J-Stage:冠状花序变白过程中抗氧化活性与代谢产物释放的关系。 A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L. PubMed:解除依赖茉莉花的植物防御，使非蛇形拟南芥植物可以被美国蛇形散叶虫所利用。 Disarming the jasmonate-dependent plant defense makes nonhost Arabidopsis plants accessible to the American serpentine leafminer. PubMed:多食性mi虫的偏好 Preference of a polyphagous mirid bug, apolygus 卢科鲁姆 lucorum（meyer-dür）用于开花寄主植物。 PubMed:所选约旦药用植物的甲醇提取物的黄嘌呤氧化酶抑制活性。 Xanthine oxidase inhibitory activity of the methanolic extracts of selected Jordanian medicinal plants. PubMed:地中海野生植物可减少代谢综合征患者的餐后血小板聚集。 Mediterranean wild plants reduce postprandial platelet aggregation in patients with metabolic syndrome. PubMed:电子废物回收站附近土壤和植被中多氯联苯的特性和风险评估 Characterization and risk assessment of polychlorinated biphenyls in soils and vegetations near an electronic waste recycling site, 中国南方。 South China. PubMed:冠状花序变白过程中抗氧化活性与代谢产物释放的关系。 A Correlation between Antioxidant Activity and Metabolite Release during the Blanching of Chrysanthemum coronarium L. PubMed:树突状细胞产生toll样受体依赖性的il-12是激活由冠状花序l诱导的自然杀伤细胞介导的1型免疫所必需的。 Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L. PubMed:精选植物水馏出物提取物对室内蚊子的杀幼虫活性 Larvicidal activity of selected plant hydrodistillate extracts against the house mosquito, 蚊子 Culex pipiens, 西尼罗河 载体。 a West Nile virus vector. PubMed:约旦花环空中部分的挥发油剖面 Volatile oil profiles of the aerial parts of Jordanian garland, 菊花冠状花序。 Chrysanthemum coronarium. PubMed:分离出产生 的真菌（青霉菌属mh7），并促进冠状菊的生长（菊花冠状花序）。 Isolation of a gibberellin-producing fungus (Penicillium sp. MH7) and growth promotion of Crown daisy (Chrysanthemum coronarium). PubMed:通过阳离子表面活性剂增强的土壤保留能力来减少植物对pah的吸收。 Reducing plant uptake of PAHs by cationic surfactant-enhanced soil retention. PubMed:鞣质艾草（trevir）sch超临界提取物的化学和生物学比较。 bip。与撒丁岛（意大利）的三种相关菊花。 Chemical and biological comparisons on supercritical extracts of Tanacetum cinerariifolium (Trevir) Sch. Bip. with three related species of chrysanthemums of Sardinia (Italy). PubMed:昆虫传播局部接种法在洋葱黄质原体的植物动态分析中的应用 In planta dynamic analysis of onion yellows phytoplasma using localized inoculation by insect transmission. PubMed:不会引起发育迟缓或韧皮部增生的洋葱黄质原体衍生系的分离和鉴定。 Isolation and Characterization of Derivative Lines of the Onion Yellows Phytoplasma that Do Not Cause Stunting or Phloem Hyperplasia. PubMed:菊花冠状花序中的杂环化合物。及其对hacat-1的抑制活性 Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hacat-2 hACAT-2, 和ldl-氧化。 and LDL-oxidation. PubMed:烟酰胺在高等植物中的代谢命运。 Metabolic fate of nicotinamide in higher plants. PubMed:菊花中铜的积累和耐性l。苏丹草和高粱 Copper accumulation and tolerance in Chrysanthemum coronarium L. and Sorghum sudanense L. PubMed:菊花中油中菜油甾醇的鉴定及其抗血管生成活性。 Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities. PubMed:灰飞虱寄主偏好与寄主叶片营养及叶绿素含量的关系 [Relationships between host preference of Liriomyza huidobrensis (Blanchard) and nutrient and chlorophyll contents in host foliage]. PubMed: 可生物降解的螯合剂乙二胺二琥珀酸通过减轻水培生长的菊花日光浴 coronarium l中的铜毒性来减少铜的吸收。 PubMed:lc / dad-apci / ms对三种菊科植物中的主要类黄酮和咖啡酰奎尼酸进行鉴定和表征。 Identification and characterization of major flavonoids and caffeoylquinic acids in three Compositae plants by LC/DAD-APCI/MS. PubMed:edds和edta增强了从 工污染土壤中提取金属的植物以及螯合剂化合物的残留作用。 EDDS and EDTA-enhanced phytoextraction of metals from artificially contaminated soil and residual effects of chelant compounds. PubMed:参照共轭亚油酸cis-9，喂食地中海饲草的绵羊的牛奶和奶酪脂肪酸组成 Milk and cheese fatty acid composition in sheep fed Mediterranean forages with reference to conjugated linoleic acid cis-9,跨11。 trans-11. PubMed:一些传统地中海饮食植物提取物的抗炎作用。 Anti-inflammatory effects of extracts from some traditional Mediterranean diet plants. PubMed:两个异果杂草菊科的芽要求和散布时间。 Germination requirements and dispersal timing in two heterocarpic weedy asteraceae. PubMed:在病原体感染的花环菊花冠状花序中积累了与病程相关的5型蛋白。 Accumulation of pathogenesis-related type-5 like proteins in phytoplasma-infected garland chrysanthemum Chrysanthemum coronarium. PubMed:气相色谱/质谱选择性检测多残留法测定韩国家庭农作物中的农药。 Multiresidue method for the determination of pesticides in Korean domestic crops by gas chromatography/mass selective detection. PubMed: 花环菊花（Chronsanthemum 日光浴 coronarium l。）中多酚氧化酶的分离纯化和表征。 PubMed:花粉香气的差异 Differences in the fragrances of pollen, 树叶 leaves, 花环的花和花的部位（菊花冠状花序）以及花头和树叶的香精油成分。 and floral parts of garland (Chrysanthemum coronarium) and composition of the essential oils from flowerheads and leaves. PubMed:菊科植物二氢菊苣醇化物及其1-末端的分离与鉴定。 Isolation and identification of dihydrochrysanolide and its 1-epimer from Chrysanthemum coronarium L. PubMed: 菊科林 chrysancorin的纯化 , 花环菊花种子中一种具有促有丝分裂活性的新型抗真菌蛋白。 a novel antifungal protein with mitogenic activity from garland chrysanthemum seeds. PubMed:花环菊花头花精油对农业病原菌的抗真菌活性。 Antifungal activity of the essential oil of flowerheads of garland chrysanthemum (Chrysanthemum coronarium) against agricultural pathogens. PubMed:花环中抗氧化剂的稳定性和生物利用度（菊花冠状花序l。）。 Stability and bioavailability of antioxidants in garland (Chrysanthemum coronarium L.). PubMed:小亚基的色谱分离（psbw / psay）并将其分配给光系统i反应中心。 Chromatographic separation of a small subunit (PsbW/PsaY) and its assignment to Photosystem I reaction center. PubMed:[花环菊花中的氧蒽醌和类黄酮]。 [Oxyanthraquinones and flavonoids from garland chrysanthenum]. PubMed:4种菊科植物之间的交叉敏感性模式 Pattern of cross-sensitivity between 4 Compositae plants, 爬山hy Parthenium hysterophorus, 黄药层 Xanthium strumarium, 向日葵和菊花冠状花序 Helianthus annuus and Chrysanthemum coronarium, 在印度患者中。 in Indian patients. PubMed:埃及五种植物的根际真菌。 Rhizosphere fungi of five plants in Egypt. PubMed:菊花的荧光花瓣成分l。 Fluorescent petal constituents of Chrysanthemum coronarium L. PubMed:水分对污泥改良土壤中克霉唑和氟康唑有效性和持久性的影响 Influence of moisture on the availability and persistence of clotrimazole and fluconazole in sludge-amended soil. PubMed:抗真菌药克霉唑在农业土壤中的命运。 Fate of the antifungal drug clotrimazole in agricultural soil. PubMed:量限制和药物化合物对锯缘ala幼虫发育和形态的影响 Effects of food limitation and pharmaceutical compounds on the larval development and morphology of Palaemon serratus. PubMed:生物固体施用后，在生物固体改良过的土壤和植物中使用典型的唑类杀生物剂。 Typical azole biocides in biosolid-amended soils and plants following biosolid applications. PubMed:毛细管电泳法测定小鼠血浆中克霉唑的含量。 Determination of clotrimazole in mice plasma by capillary electrophoresis. PubMed:克霉唑/倍他米松双丙酸酯 Clotrimazole/betamethasone diproprionate: 常见皮肤真菌感染的治疗费用和并发症的综述。 a review of costs and complications in the treatment of common cutaneous fungal infections. PubMed:性别的影响 Influence of gender, 喂养方案 feeding regimen, 和暴露持续时间对黑头now鱼（pimephales 普罗梅拉斯 promelas）异种生物代谢相关基因表达的影响。 PubMed:在受城市污水处理厂废水影响的小溪底栖动物中存在药品。 Presence of pharmaceuticals in benthic fauna living in a small stream affected by effluent from a municipal sewage treatment plant. PubMed: 妊娠x受体（pxr）结合的qsar模型 QSAR model for human pregnane X receptor (PXR) binding: 天然化合物作为keap1-nrf2途径的激活剂的筛选。 screening of environmental chemicals and correlations with genotoxicity, 内分泌破坏和致畸性。 endocrine disruption and teratogenicity. PubMed:合成与协同 Synthesis and synergistic, 新型螺衍生物对癣菌感染的累加抑制作用。 additive inhibitory effects of novel spiro derivatives against ringworm infections. PubMed:来自食品和药物管理局。 From the Food and Drug Administration. PubMed:非处方 类使用的局部抗真菌药物产品；修改最后的专着。最终规则。 Topical antifungal drug products for over-the-counter human use; amendment of final monograph. Final rule. PubMed:念珠菌病（口咽）。 Candidiasis (oropharyngeal). PubMed: 花生四烯酸增加白念珠菌和dubliniensis dubliniensis念珠菌的抗真菌药性。 PubMed:两种方案在下 器感染综合征治疗中的比较功效。 Comparative efficacy of two regimens in syndromic management of lower genital infections. PubMed:使用聚合物共混物稳定含有固溶体的热熔挤出配方。 Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends. PubMed:念珠菌病（口咽）。 Candidiasis (oropharyngeal). PubMed:在美沙拉嗪或没药的草药制剂治疗期间出现耀斑的溃疡性结肠炎患者外周血cd4 + t细胞的频率具有明显的动力学变化 Development of stably transfected human and rat hepatoma cell lines for the species-specific assessment of xenobiotic response enhancer module (XREM)-dependent induction of drug metabolism. PubMed:热熔挤出聚环氧乙烷薄膜的固态稳定性和表征。 Solid-state stability and characterization of hot-melt extruded poly(ethylene oxide) films. PubMed:咪康唑局部口服治疗鼻咽念珠菌病 Management of oropharyngeal candidiasis with localized oral miconazole therapy: 功效 efficacy, 安全 Safety, 和患者的可接受性。 and patient acceptability. PubMed:氧化还原活性化合物和pxr激活剂对 mrp1和mrp2基因表达的影响。 Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression. PubMed:Athlete's foot. PubMed:氟康唑在外阴阴道念珠菌病的治疗中有什么作用？ Is there a role for fluconazole in the treatment of vulvovaginal candidiasis? PubMed:乳品微生物的安全性评估 Safety assessment of dairy microorganisms: 念珠菌。 Geotrichum candidum. PubMed:抗真菌药 Antimycotic 活动 activity of 5'-prenylisoflavanones of the plant 泥土 Geoffroea 装饰的 decorticans, 反对曲霉菌​​种。 against Aspergillus species. PubMed:各种处方药和非处方外用抗真菌药物产品抑制c。生长的比较能力。白的。 Comparative ability of various prescription and over-the-counter topical antifungal drug products to inhibit the growth of C. albicans. PubMed:靶向癌症能量代谢。 Targeting of cancer energy metabolism.

笔记 Notes: 具有广谱抗霉菌活性的咪唑衍生物。它抑制甾醇麦角甾醇的生物合成 an imidazole derivative with a broad spectrum of antimycotic activity. it inhibits biosynthesis of the sterol ergostol, 当归种子油当归种子eo当归种子es fca 45当归种子精油当归种子油当归种子油fcc当归种子油法国当归种子诺维加卡种子油从当归植物种子中获得的精油 an important component of fungal cell membranes. its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Clotrimazole is an imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, 真菌细胞膜的重要组成部分。其作用导致增加的膜渗透性和与膜结合的酶系统的明显破坏。 -pubchem;如果口服，可能会与克霉唑发生药物相互作用 an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. -- Pubchem; There is the potential for drug interactions with Clotrimazole if taken orally, 因为它很有效 as it is a potent, 有致癌性。由此造成的危害程度是一个分歧的主题。出售用于洗涤衣服的家用漂白剂在生产时是3-6％的次氯酸钠溶液。强度从一种配方变化到另一种配方，并随着长期保存而逐渐降低。次氯酸钠是化学式为naclo的化合物。次氯酸钠溶液 specific inhibitor of cytochrome P450 oxidase enzymes and so may alter the metabolism of other drugs.; Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections and ringworm. -- Wikipedia; An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, 皮肤和皮肤.r 41-眼睛受到严重伤害的危险.s 01/02-锁紧并放在儿童接触不到的地方.s 16-远离火源-禁止吸烟.s 20/21-使用时不吃 an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.; Clotrimazole is a potent, 细胞色素p450氧化酶的特异性抑制剂。因此 specific inhibitor of cytochrome P450 oxidase enzymes. Hence, it 可以 may alter the 代谢 metabolism of other 毒品 药品 drugs 尤其 particularly if 已采取 taken 口头 口服 orally. -- 维基百科 Wikipedia; Clotrimazole is an 抗真菌药 anti真菌的 fungal 药物 medication 通常 共同 commonly 用过的 used in the 治疗 对待 treatment of 真菌的 fungal 感染 感染 infections of 都 both 类 的 humans and 动物 animals 这样 such as 阴道 vaginal 酵母 yeast 感染 感染 infections and 癣 ringworm. it It 也 also 用过的 used to 对待 treat athlete's foot and 乔克 jock 痒 itch. [HMDB]