分离。从咖喱叶（murraya koenigii）和八角茴香油（illicium religiosum）提取 Isol. from leaves of the curryleaf (Murraya koenigii) and from star anise oil (Illicium religiosum) it It is a 前体 precursor in the 合成 synthesis of the 杀虫剂 insecticide 增效剂 synergist 胡椒基 piperonyl 丁氧化物 but butoxide and the 休闲的 recreational 药品 drug mdma MDMA ("狂喜 Ecstacy."); 紫杉醇 Safrole is a natural plant 组分 constituent, 在树油和某些其他精油中发现。它是化合物的亚甲二氧基苯的成员 found in oil of sassafras and certain other essential oils. It is a member of the methylenedioxybenzene group of compounds, 其中许多（例如胡椒基丁醚）被广泛用作杀虫剂增效剂。 类接触黄樟脑的主要来源是通过食用香料 many of which (e.g. piperonyl butoxide) are extensively used as insecticide synergists. A major source of human exposure to safrole is through consumption of spices, 如肉豆蔻 such as nutmeg, 肉桂和黑胡椒 cinnamon and black pepper, 其中黄樟脑是成分。根啤酒中也存在黄樟脑 in which safrole is a constituent. Safrole is also present in root beer, 并已被用作口香糖的添加剂 and has been used as an additive in chewing gum, 牙膏 toothpaste, 肥皂和某些药物制剂。紫杉醇是一种弱肝癌致癌物，无论是ally1部分还是亚甲二氧基都令 关注 soaps and certain pharmaceutical preparations. Safrole is a weak hepatocarcinogen and it is a matter of considerable interest whether the ally1 moiety or the methylenedioxy group, 或两者 or both, are 涉及 involved in the 机制 mechanism of its 致癌作用 carcinogenesis. 紫杉醇 Safrole is 广泛地 extensively 代谢 metabolized, 产生大量的代谢产物。代谢本质上涉及两个主要途径 giving rise to a large number of metabolites. Metabolism involves essentially two major routes, ally1侧链的氧化 oxidation of the ally1 side chain, and 氧化 oxidation of the 亚甲二氧基 methylenedioxy group with 随后的 subsequent 分裂 cleavage to form the 儿茶酚 catechol. 紫杉醇 Safrole 经历 undergoes 氧化 oxidation of the 盟友 allylic group to 让 yield the 2, 3-epoxide (safrole epoxide). The 二氢dihydrodiol is one of the metabolites of safrole, and 想必 presumably 出现 a上升 rises from the 水合 hydration of the 2, 3-epoxide. The 主要 principal 路线 route of 代谢 metabolism of safrole is 通过 through 分裂 cleavage of the 亚甲二氧基 methylenedioxy group, 主要代谢产物是烯丙基邻苯二酚及其异构体 the major metabolites being allylcatechol and its isomer, 丙烯基儿茶酚。丁香酚及其异构体异甲氧基-2-羟基-4-烯丙基苯在大鼠中被检测为次要代谢产物 propenylcatechol. Eugenol and its isomer I-methoxy- 2-hydroxy-4-allylbenzene have been detected as minor metabolites in the rat, 鼠标和 。 （pmid mouse and man. (PMID: 6719936）；紫杉醇 6719936); Safrole, 又称sh草 also known as shikimol, 是无色或淡黄油状液体。它通常是从assa树植物的根皮或果实中提取的，形式为树油 is a colorless or slightly yellow oily liquid. It is typically extracted from the root-bark or the fruit of sassafras plants in the form of sassafras oil, 或由其他相关的亚甲二氧基化合物合成。它是棕色樟脑油的主要成分 or synthesized from other related methylenedioxy compounds. It is the principal component of brown camphor oil, 并在各种植物中少量发现 and is found in small amounts in a wide variety of plants, 它起天然杀虫剂的作用。燕麦茶汁[需要验证] where it functions as a natural pesticide. The Ocotea cymbarum[verification needed] oil made of the Ocotea pretiosa[verification needed], 巴西生长的植物 a plant growing in Brazil, 和al油制成的木 and sassafras oil made of Sassafras albidum, 北美东部生长的树 a tree growing in eastern North America, are the 主要 main natural 资料来源 sources for safrole. it It 已 has a 特性 characteristic "糖果店 candy-shop" aroma.