2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
2,4-间苯二酸 4-resorcylic acid

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    89-86-1 2,4-二羟基苯甲酸98% 4-Dihydroxybenzoic Acid 98%
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    w379808 2 W379808 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid, ≥97%
    SDS
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    d0568 2 D0568 2,4-二羟基苯甲酸> 98.0%(t) 4-Dihydroxybenzoic Acid >98.0%(T)
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    2,4-二羟基苯甲酸 4-dihydroxybenzoic acid, 97+%
Name:2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
CAS号 CAS Number: 89-86-1Picture of molecule3D/INCHI
ECHA EINECS - REACH 预注册 Pre-Reg:201-946-9
FDA UNII:LU39SC9JYL
nikkaji网站 Nikkaji Web:J4.310I
贝尔斯坦数 Beilstein Number:1946213
MDL :mfcd00002451 MFCD00002451
XlogP3:1.60(est) 1.60 (est)
分子量 Molecular Weight:154.12162000
式 Formula:c7 h6 o4 C7 H6 O4
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
efsa / jecfa评论 EFSA/JECFA Comments:
根据jecfa According to JECFA: 融化 Melting 点 point is "225� (分解 decomposes, 快速 rapid 加热 heating required)".
类别 Category:flavoring agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
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pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
jecfa食品调味料 JECFA Food Flavoring:908 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
Flavis号码 FLAVIS Number:08.076(旧) 08.076 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:08.076 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
fema号 FEMA Number:3798 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
自由贸易区 FDA:不再提供这七种合成调味剂的使用 No longer provide for the use of these seven synthetic flavoring substances
fda mainterm(satf) FDA Mainterm (SATF):89-86-1 ; 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
 
物理性质 Physical Properties:
出现 Appearance:白结晶性粉末(est) white crystalline powder (est)
化验 Assay: 97.00至100.00 97.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 225.00 to 227.00 °C. @ 760.00 mm 汞 Hg
闪点 Flash Point: 425.00 °F. tcc TCC ( 218.33 °C. )
logp(o / w) logP (o/w): 1.630
溶于 Soluble in:
 alcohol
 水 water, 1.122e+004 mg/L @ 25 &deg °C (est)
 水 water, 5780 mg / l @ 25°C(实验) 5780 mg/L @ 25 °C (exp)
不溶于 Insoluble in:
 水 water
 
感官特性 Organoleptic Properties:
气味强度 Odor Strength:low
气味描述 Odor Description:at 100.00 %. 轻度 mild 酚醛的 phenolic
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
Beijing Lys Chemicals
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
2,4-二羟基苯甲酸98% 4-Dihydroxybenzoic Acid 98%
Emd 微孔 Millipore
仅供实验/研究使用。 For experimental / research use only.
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
外合成 ExtraSynthese
仅供实验/研究使用。 For experimental / research use only.
β-间苯二酸(hplc)≥90% beta-Resorcylic acid (HPLC) ≥90%
jalor-chem Jalor-Chem
仅供实验/研究使用。 For experimental / research use only.
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
Parchem Parchem
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
Penta International
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
Sigma-Aldrich
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid, ≥97%
认证食品级产品 Certified Food Grade Products
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
2,4-二羟基苯甲酸> 98.0%(t) 4-Dihydroxybenzoic Acid >98.0%(T)
WholeChem
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid, 97+%
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
欧洲信息 European information :
最重要的危害 Most important hazard(s):
xi-刺激性 Xi - Irritant
r 36/37/38-刺激眼睛 R 36/37/38 - Irritating to eyes, 呼吸系统 respiratory system, and skin 皮.
S 02 - 保持 Keep out of the 达到 reach of 孩子们 children.
S 24/25 - 避免 Avoid contact with skin 皮 and 眼睛 eyes.
S 26 - In 案件 case of contact with 眼睛 eyes, 冲洗 rinse 立即 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical advice.
S 36 - 穿 Wear 适当 suitable 保护性 protective 服装 clothing.
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
腹腔内小鼠 intraperitoneal-mouse LD50 > 800 mg/kg
高 Highest 剂量 dose applied was not 致死 lethal.
(格雷迪 Grady et al., 1976)

腹腔内小鼠 intraperitoneal-mouse LD50 > 800 mg/kg
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 196, pg。 478 Pg. 478, 1976.

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
flavoring agents
2推荐 Recommendation for 2,4-二羟基苯甲酸使用量高达 4-dihydroxybenzoic acid usage levels up to:
 不用于香水。 not for fragrance use.
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 5.50(微克/ 均/天) 5.50 (μg/capita/day)
最大化源自调查的每日摄入量(msdi-usa) Maximised Survey-derived Daily Intakes (MSDI-USA): 6.00(微克/ 均/天) 6.00 (μg/capita/day)
结构类 Structure Class: I
采用 Use 等级 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its 判断 judgments that the 物质 substances are 通常 generally 公认的 recognized as safe (GRAS).
The 专家 Expert 面板 Panel 也 also 发表 publishes 分离 separate 广泛 extensive 评论 reviews of scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library
出版编号 publication number: 17
点击这里查看出版物17 Click here to view publication 17
 平均 average 通常 usual 百万分之几 ppm平均 average 最大 maximum 百万分之几 ppm
焙烤食品 baked goods: --
饮料(不含醇) beverages(nonalcoholic): 500.00000500.00000
醇饮料 beverages(alcoholic): 500.00000500.00000
早餐麦片 breakfast cereal: 500.00000500.00000
起司 cheese: 500.00000500.00000
口香糖 chewing gum: 3333.000003333.00000
调味品/调味品 condiments / relishes: 500.00000500.00000
糖果烧烤 confectionery froastings: --
蛋制品 egg products: 500.00000500.00000
脂肪/油 fats / oils: 500.00000500.00000
鱼产品 fish products: 500.00000500.00000
冷冻乳制品 frozen dairy: 450.00000450.00000
水果冰 fruit ices: 500.00000500.00000
明胶/布丁 gelatins / puddings: 500.00000500.00000
砂糖 granulated sugar: --
肉汁 gravies: 500.00000500.00000
硬糖 hard candy: --
仿乳制品 imitation dairy: 500.00000500.00000
速溶咖啡/茶 instant coffee / tea: 125.00000125.00000
果酱/果冻 jams / jellies: 500.00000500.00000
肉制品 meat products: 100.00000100.00000
奶制品 milk products: 100.00000100.00000
坚果产品 nut products: 500.00000500.00000
其他谷物 other grains: --
家禽 poultry: 500.00000500.00000
加工水果 processed fruits: --
加工蔬菜 processed vegetables: 100.00000100.00000
重构蔬菜 reconstituted vegetables: 500.00000500.00000
调味料 seasonings / flavors: 25000.0000025000.00000
休闲食品 snack foods: 500.00000500.00000
软糖 soft candy: 500.00000500.00000
汤类 soups: 250.00000250.00000
糖替代品 sugar substitutes: 12500.0000012500.00000
甜酱 sweet sauces: 500.00000500.00000
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 seasonings / flavors, 与调味品组评估有关的委员会的要求20(fge.20)与食品接触的加工助剂和材料(afc) processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical group 23
视图 View page or 视图 View pdf

调味组评估52(fge.52) Flavouring Group Evaluation 52 (FGE.52): 通过与构烷醇相关的jecfa(第五十七次会议)评估的羟基和烷氧基取代的苄基衍生物的考虑 Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, efsa EFSA在ge FGE.20(2005)(委员会法规(ec EC)2000年7月18日第1565/2000号)中评估的食品及相关酯-食品添加剂科学小组的意见 , 调味料 seasonings / flavors, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (AFC)
视图 View page or 视图 View pdf

调味组评估20 Flavouring Group Evaluation 20, 版本1(fge.20rev1) Revision 1 (FGE.20Rev1): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids and 有关 related esters from chemical group 23
视图 View page or 视图 View pdf

调味品组评价的科学见解20 Scientific Opinion on Flavouring Group Evaluation 20, 版本2(fge.20rev2) Revision 2 (FGE.20Rev2): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical 团体 groups 23 and 30
视图 View page or 视图 View pdf

调味品组评价的科学见解20 Scientific Opinion on Flavouring Group Evaluation 20, 版本3(fge.20rev3) Revision 3(FGE.20Rev3): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical 团体 groups 23 and 30
视图 View page or 视图 View pdf

关于调味剂组评估的科学意见96(fge.96) Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): 核酸酶p1富集和32p后标记分析后,检测经n-羟基-4-氨基联苯处理的 尿道上皮细胞dna中的脱氧腺苷-4-氨基联苯加合物。 Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87.
视图 View page or 视图 View pdf

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EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :1491
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
chemidplus Chemidplus:0000089861
技术 RTECS:适用于CAS#89-86-1的vh3708050 VH3708050 for cas# 89-86-1
 
参考资料 References:
 2,4-二羟基苯甲酸 4-dihydroxybenzoic acid
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):1491
pubchem(sid) Pubchem (sid):134970609
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
CHEMBL:视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB29666
食物 FooDB:FDB000842
出口关税代码 Export Tariff Code:2918.29.7500
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None found
 
潜在用途 Potential Uses:
没找到 None found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 鳄梨 avocado
搜索 Search Trop Picture
 beer
搜索 Search pmc PMC Picture
 洋甘菊甜假洋甘菊植物 chamomile sweet false chamomile plant
搜索 Search Trop Picture
 coffee
搜索 Search pmc PMC Picture
 柳叶 willow leaf
搜索 Search Picture
 
同义词 Synonyms:
4-carboxyresorcinol
2,4-dihydroxy benzoic acid
2,4-dihydroxy-benzoic acid
4-hydroxysalicylic acid
p-hydroxysalicylic acid
para-hydroxysalicylic acid
beta-resorcinolic acid
2,4-resorcylic acid
b-resorcylic acid
beta-resorcylic acid
 
 
笔记 Notes:
在鳄梨中发现 Found in avocado, beer, 葡萄酒和咖啡。食品风味成分和风味改良剂 wine and coffee. Food flavour ingredient and flavour modifier
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