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类别 Category:antioxidants and preservatives
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 出现 Appearance: | 白至微黄结晶性粉末（est） white to yellowish crystalline powder (est) |
| 化验 Assay: | 98.00至100.00 98.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 沸点 Boiling Point: | 415.00 to 416.00 °C. @ 760.00 mm 汞 Hg
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| 蒸汽压力 Vapor Pressure: | 0.000000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) |
| 闪点 Flash Point: | 356.00 °F. tcc TCC ( 180.00 °C. )
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| logp（o / w） logP (o/w): | -2.653（est） -2.653 (est) |
| 溶于 Soluble in: |
| | 水 water, 1e+006 mg/L @ 25 ＆deg °C (est) | | | alcohol, 略 slightly |
| 不溶于 Insoluble in: |
| | ether |
感官特性 Organoleptic Properties:
| 气味描述 Odor Description:at 100.00 %. 无味的 odorless |
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
| |
| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
|
未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | | antioxidants and preservatives |
| 推荐抗坏血酸钙的使用水平达到 Recommendation for calcium ascorbate usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 推荐抗坏血酸钙调味剂的使用水平最高为 Recommendation for calcium ascorbate flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
欧洲食品安全局（efsa EFSA）参考 :
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声明 Statement of efsa EFSA on the safety of calcium 抗坏血酸 L-ascorbate with a content of 苏糖酸盐 threonate produced by by a new 制造业 manufacturing 处理 process as a source of vitamin C in food 补品 补充 supplements
视图 View page or 视图 View pdf
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关于维生素C（抗坏血酸）的安全性和有效性的科学见解 Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, 抗坏血酸sodium ascorbate, 抗坏血酸钙 Calcium Ascorbate USP, 棕榈酸抗坏血酸酯 ascorbyl palmitate, sodium calcium 抗坏血酸 ascorby byl phosphate and sodium 抗坏血酸 ascorby byl phosphate) as a feed additive for all animal 种类 species 基于 based on a 卷宗 dossier submitted by by DSM 营养的 Nutritional 产品展示 Products Ltd
视图 View page or 视图 View pdf
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关于抗坏血酸重新评估的科学见解（e 300） Scientific Opinion on the re-evaluation of ascorbic acid (E 300), 抗坏血酸sodium ascorbate (E 301) and 抗坏血酸钙 Calcium Ascorbate USP (E 302) as food additives
视图 View page or 视图 View pdf
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| Epi系统 EPI System: 视图 View |
| nlm NLM有害物质数据库 :搜索 Search |
| 化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search |
| 毒理学引文 Toxicology Citations:搜索 Search |
| 橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search |
| EPA物质注册服务（tsca TSCA） :5743-27-1 |
| EPA ACToR:毒理学资料 Toxicology Data |
| EPA物质注册服务（SRS） :注册表 Registry |
| 实验室化学安全摘要 Laboratory Chemical Safety Summary :54678500 |
| 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data |
| 德国wgk WGK Germany:1 |
| 钙5-[（1s）-1 calcium 5-[(1S)-1,2-二羟乙基] -3-羟基-4-氧呋喃-2-油酸酯 2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate |
| chemidplus Chemidplus:0005743271 |
参考资料 References:
| | 钙5-[（1s）-1 calcium 5-[(1S)-1,2-二羟乙基] -3-羟基-4-氧呋喃-2-油酸酯 2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 5743-27-1 |
| pubchem（cid） Pubchem (cid): | 54678500 |
| pubchem（sid） Pubchem (sid): | 134988883 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and 核心组件 core components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | ascorbate calcium | | L- | 抗坏血酸 ascorbic acid calcium 盐 salt (2:1) | | laevo- | 抗坏血酸 ascorbic acid calcium 盐 salt (2:1) | | | 钙5-[（1s）-1 calcium 5-[(1S)-1,2-二羟乙基] -3-羟基-4-氧呋喃-2-油酸酯 2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate | | hemi | 抗坏血酸钙 Calcium Ascorbate USP | | | 抗坏血酸钙 Calcium Ascorbate USP 8.93 dc DC 粒状 granular | | | 抗坏血酸钙 Calcium Ascorbate USP 97% dc DC | | | 抗坏血酸钙 Calcium Ascorbate USP 98%-101% | | | 抗坏血酸钙 Calcium Ascorbate USP 二水合物 dihydrate 9.4 | | | 抗坏血酸钙 Calcium Ascorbate USP fcc fcc FCC | | | 抗坏血酸钙 Calcium Ascorbate USP with added added 苏糖酸盐 threonate | | | calcium diascorbate | | | calcium 抗坏血酸 L-ascorbate | | | calcium 抗坏血酸 laevo-ascorbate |
文章 Articles:
| 信息 Info:评估某些食品添加剂和污染物 EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS |
| 已发布 PubMed:烤和增湿对剔除牛牛肉食用品质的影响 Effects of hot boning and moisture enhancement on the eating quality of cull cow beef. |
| 已发布 PubMed:乳酸钾和抗坏血酸钙作为氯化钠替代品对低钠法兰克福香肠的理化和感官特性的综合影响。 Combined effects of potassium lactate and calcium ascorbate as sodium chloride substitutes on the physicochemical and sensory characteristics of low-sodium frankfurter sausage. |
| 已发布 PubMed:干发酵香肠中钠的减少以及钙和ω-3多不饱和脂肪酸增加 Reduction of sodium and increment of calcium and ω-3 polyunsaturated fatty acids in dry fermented sausages: 对矿物质含量的影响 effects on the mineral content, 脂质分布和感觉质量。 lipid profile and sensory quality. |
| 已发布 PubMed:-甲基环丙烯和后控制空气贮藏处理对鲜切苹果片的影响 Effects of 1-methylcyclopropene and post-controlled atmosphere air storage treatments on fresh-cut Ambrosia apple slices. |
| 已发布 PubMed:骨骼分离和水分增强对提高牛犊食用质量的影响。 The effects of skeletal separation and moisture enhancement for improving the eating quality of cull cow beef. |
| 已发布 PubMed:补充剂中允许的维生素A和C化合物影响细胞活力的能力不同 Vitamin A and C compounds permitted in supplements differ in their abilities to affect cell viability, dna和dna核苷脱氧鸟苷。 DNA and the DNA nucleoside deoxyguanosine. |
| 已发布 PubMed:表面处理和涂层，以保持鲜切芒果的品质。 Surface treatments and coatings to maintain fresh-cut mango quality in storage. |
| 已发布 PubMed:苹果片中硫酸钠的抗褐变和抗菌性能。 Antibrowning and antimicrobial properties of sodium acid sulfate in apple slices. |
| 已发布 PubMed:维生素C与代谢产物 Vitamin C with metabolites: 其他分析表明草酸盐发生了有利的变化。 additional analysis suggests favorable changes in oxalate. |
| 已发布 PubMed:与抗坏血酸相比，含代谢物的维生素C降低草酸水平 Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: 初步和新颖的临床泌尿外科发现。 a preliminary and novel clinical urologic finding. |
| 已发布 PubMed:剂与有机酸结合对大肠杆菌o157的影响 Effect of tenderizers combined with organic acids on Escherichia coli O157:非完整牛肉的h7耐热性。 H7 thermal resistance in non-intact beef. |
| 已发布 PubMed:利用ft-近红外光谱技术对usp小瓶内的某些药物赋形剂进行无创原位鉴定和谱带分配。 Noninvasive in situ identification and band assignments of some pharmaceutical excipients inside USP vials with FT-near-infrared spectroscopy. |
| 已发布 PubMed:维生素C脂质代谢产物 Vitamin C-lipid metabolites: 吸收和保留以及对健康志愿者血浆c反应蛋白和氧化的ldl水平的影响。 uptake and retention and effect on plasma C-reactive protein and oxidized LDL levels in healthy volunteers. |
| 已发布 PubMed:维生素C代谢物 Vitamin C metabolites, 与吸烟状况无关 independent of smoking status, 显着增强明串球菌 significantly enhance leukocyte, 但血浆抗坏血酸浓度 but not plasma ascorbate concentrations. |
| 已发布 PubMed:大肠杆菌o157的热灭活 Thermal inactivation of Escherichia coli O157:用腌制和嫩化成分处理过的牛肉中的h7。 H7 in beef treated with marination and tenderization ingredients. |
| 已发布 PubMed:各种局部制剂中棕榈酸抗坏血酸酯和抗坏血酸钙的保湿潜能。 Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations. |
| 已发布 PubMed: 对鲜切水果和蔬菜中呋喃形成的影响 Effect of ionizing radiation on furan formation in fresh-cut fruits and vegetables. |
| 已发布 PubMed:通过顺序处理消毒剂和抗坏血酸钙来控制鲜切苹果褐变和微生物生长。 Control of browning and microbial growth on fresh-cut apples by sequential treatment of sanitizers and calcium ascorbate. |
| 已发布 PubMed:淋巴细胞中维生素C脂质代谢产物的吸收率和自由基清除率 Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells. |
| 已发布 PubMed:比较了抗坏血酸和抗坏血酸钙与生育酚在乳液中的保湿效果。 Comparing the moisturizing effects of ascorbic acid and calcium ascorbate against that of tocopherol in emulsions. |
| 已发布 PubMed:与常规抗坏血酸相比，酯c的安全性和耐受性。 Safety and tolerance of ester-C compared with regular ascorbic acid. |
| 已发布 PubMed:抗坏血酸安全性评估的最终报告 Final report of the safety assessment of L-Ascorbic Acid, 抗坏血酸钙 Calcium Ascorbate USP, 抗坏血酸镁 Magnesium Ascorbate, 抗坏血酸磷酸镁 Magnesium Ascorbyl Phosphate, 抗坏血酸sodium ascorbate, 以及化妆品中使用的抗坏血酸磷酸钠。 and Sodium Ascorbyl Phosphate as used in cosmetics. |
| 已发布 PubMed:酸对抗坏血酸钙溶液中无毒李斯特菌存活率和鲜切苹果品质的影响。 Effect of pH on the survival of Listeria innocua in calcium ascorbate solutions and on quality of fresh-cut apples. |
| 已发布 PubMed:大鼠抗坏血酸钙和乙酸钙的钙生物利用度和动力学。 Calcium bioavailability and kinetics of calcium ascorbate and calcium acetate in rats. |
| 已发布 PubMed:[在抗坏血酸钙治疗期间减轻了髋香柳叶菜或膝香柳叶菜骨节螺藻的疼痛。随机的 [Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, 一般实践中安慰剂对照的交叉试验]。 placebo-controlled cross-over trial in general practice]. |
| 已发布 PubMed: 钙盐对牛肉长经 longissimus品质的影响。 |
| 已发布 PubMed:处理和山梨酸酯添加量对苹果酒风味特征的影响 Effects of processing treatment and sorbate addition on the flavor characteristics of apple cider. |
| 已发布 PubMed:补充维生素C预防普通感冒 Preventing the common cold with a vitamin C supplement: 双盲 a double-blind, 安慰剂对照调查。 placebo-controlled survey. |
| 已发布 PubMed:抗坏血酸钙在干发酵香肠中可作为Nacl的部分替代品 Calcium ascorbate as a potential partial substitute for NaCl in dry fermented sausages: 对颜色的影响 effect on colour, 不同浓度下的质地和卫生质量。 texture and hygienic quality at different concentrations. |
| 已发布 PubMed: 尿中na-k-atpase的抑制剂 Inhibitors of Na-K-ATPase in human urine: 哇巴因样因子和二硬脂酸钒对大鼠血管平滑肌细胞钙动员的影响 effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: 与哇巴因的作用比较 comparison with the effects of ouabain, 血管紧张素Ⅱ angiotensin II, 和精氨酸加压素。 and arginine-vasopressin. |
| 已发布 PubMed:通过添加维生素C代谢物的抗坏血酸钙增强体外矿化结节和胶原蛋白的生产。 Enhanced production of mineralized nodules and collagenous proteins in vitro by calcium ascorbate supplemented with vitamin C metabolites. |
| 已发布 PubMed:大鼠从抗坏血酸钙中吸收钙。 Intestinal absorption of calcium from calcium ascorbate in rats. |
| 已发布 PubMed:草酸钙的吸收不需要在大鼠中解离。 Absorption of calcium oxalate does not require dissociation in rats. |
| 已发布 PubMed:哇巴因样因子和重泻钒对猪内髓收集管细胞钙动员的影响 Effects of urinary ouabain-like factors and vanadium diascorbate on calcium mobilization in porcine inner medullary collecting duct cells: 与哇巴因和加压素的作用进行比较。 comparison with the effects of ouabain and vasopressin. |
| 已发布 PubMed: 尿中哇巴因样因子 Ouabain-like factors in human urine: na-k-atpase抑制剂的鉴定为钒-二硬脂酸酯加合物。 identification of a Na-K-ATPase inhibitor as vanadium-diascorbate adduct. |
| 已发布 PubMed:非抗坏血酸合成成骨性疾病shionogi（ods）大鼠中抗坏血酸和酯c的抗坏血酸活性的比较。 Comparison of the anti-scorbutic activity of L-ascorbic acid and Ester C in the non-ascorbate synthesizing Osteogenic Disorder Shionogi (ODS) rat. |
| 已发布 PubMed:酸和脱氢抗坏血酸对组织葡萄糖吸收的影响。 Effect of ascorbate and dehydroascorbate on tissue uptake of glucose. |
| 已发布 PubMed:新型抗坏血酸钙相对胃肠道吸收的急性研究。 An acute study on the relative gastro-intestinal absorption of a novel form of calcium ascorbate. |
| 已发布 PubMed:儿童麻醉期间中性粒细胞的活动性。抗坏血酸预治疗的试验。 Neutrophil mobility during anaesthesia in children. A trial of ascorbate premedication. |
| 已发布 PubMed:抗坏血酸钙比抗坏血酸钠更好？ Is calcium ascorbate preferable to sodium ascorbate? |
| 已发布 PubMed:豚鼠肾上腺细胞对低剂量（1-50 pg / ml）的α1-24肾上腺皮质激素的反应的特征。 Characteristics of the response of dispersed guinea-pig adrenal cells to low doses (1-50 pg/ml) of alpha 1-24 adrenocorticotrophin. |
| 已发布 PubMed:肺结核细胞和体液免疫功能的体外评估 An in vitro assessment of cellular and humoral immune function in pulmonary tuberculosis: 抗坏血酸纠正中性粒细胞运动缺陷 correction of defective neutrophil motility by ascorbate, 左旋咪唑 levamisole, 美托洛尔和心得安。 metoprolol and propranolol. |
| 已发布 PubMed:激素和其他物质对体外晶状体再生的影响。 The influence of hormones and other substances on lens regeneration in vitro. |
| 已发布 PubMed:抗坏血酸对明串球菌的影响 Effects of ascorbate on leucocytes: 第三部分抗坏血酸体外和体内刺激异常嗜中性粒细胞运动。 Part III. In vitro and in vivo stimulation of abnormal neutrophil motility by ascorbate. |
| 已发布 PubMed:抗坏血酸对明串球菌的影响 Effects of ascorbate on leucocytes: 第一部分抗坏血酸对体外中性粒细胞活力和细胞内环核苷酸水平的影响 Part I. Effects of ascorbate on neutrophil motility and intracellular cyclic nucleotide levels in vitro. |
| 已发布 PubMed:抗坏血酸抑制鸡胚中6-氨基烟酰胺的致畸作用。 Ascorbate inhibition of 6-aminonicotinamide teratogenesis in chicken embryos. |
| 已发布 PubMed:冬季疾病和维生素C Winter illness and vitamin C: 较低剂量的作用。 the effect of relatively low doses. |
| 已发布 PubMed:［在耳鼻喉科中使用抗坏血酸钙的临床经验］。 [Clinical experience in the use of calcium ascorbate in otorhinolaryngology]. |
| 已发布 PubMed:抗坏血酸钙对实验动物颅骨损伤后血块吸收的影响。 The effect of calcium ascorbate on the resorption of blood clots following injury to the skull in experimental animals. |
| 已发布 PubMed:[抗坏血酸钙对骨折愈合的治疗过程的影响；实验研究]。 [The effect of calcium ascorbate on therapeutic process in fracture healing; experimental research]. |
| 已发布 PubMed:耳鼻喉科的抗坏血酸钙。 Calcium ascorbate in otolaryngology. |
| 已发布 PubMed:[肺结核中的钙和维生素c；体验新盐 [Calcium and vitamin C in pulmonary tuberculosis; experiences with a new salt, 抗坏血酸钙]。 calcium ascorbate]. |
| 已发布 PubMed:[苏联制剂抗坏血酸钙对通透性和维生素C代谢的影响]。 [Effect of the Soviet preparation of calcium ascorbate of the permeability and vitamin C metabolism]. |
| 已发布 PubMed:抗坏血酸影响 The influence of ascorbic acid, 抗坏血酸sodium ascorbate, 牙釉质上的抗坏血酸钙和橙汁。 calcium ascorbate and orange juice on dental enamel. |
| 已发布 PubMed:结晶的二水合抗坏血酸钙。 Crystalline Dihydrate of Calcium Ascorbate. |
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