食品调味剂。存在于各种植物中。例如拉丹佛斯（Labdanum） Food flavourant. Present in various plant spp. e.g. Cistus ladaniferus (labdanum) 头皮屑和脱发。在香水行业中也用作固定剂。雪松木地图集具有镇静和舒缓的镇静作用，类似于檀香木。这种油被认为具有橙花毒性和流产作用，不应用于儿童和孕妇。 Cyclohexanone is a colorless oily liquid with an odor resembling acetone and peppermint. Cyclohexanone is occasionally found as a volatile component of human urine. . Biological fluids such as blood and urine have been shown to contain a large number of components, 其中一些挥发物（低沸点）显然存在于所有个体中 some of them volatiles (low boiling point) apparently present in all individuals, 而其他的则更多。在某些情况下，观察到的差异高达一个数量级。尽管其中一些变化可能是饮食原因 while others such are much more variable. In some cases differences up to an order of magnitude are observed. Although some of these changes may have dietary origins, 其他 others 似乎 看到 seem to be 特性 characteristic of the individual. Cyclohexanone is 获得 obtained 通过 through 氧化 oxidation of cyclohexane or 脱氢 dehydrogenation of phenol. 大约 Approx. 95% of its 制造 manuf. is 用过的 used for the 生产 production of 尼龙 nylon. Information on 毒性 有毒的 toxicity to 的 human 众生 beings is 零碎的 fragmentary. 急性 Acute 接触 经验值 exposure is 特色的 characterized by by 刺激 irritation of the 眼睛 眼睛 eyes, 鼻子 nose, and 喉 throat. In 二 two persons, 发现嗜睡和肾功能损害；像环己醇 drowsiness and renal impairment were found; Like cyclohexanol, 环己酮不致癌，仅具有中等毒性 cyclohexanone is not carcinogenic and is only moderately toxic, with a 电视 TLV of 25 百万分之几 ppm for the 汽 vapor. it It is an 刺激性的 irritant.; The 大 great 多数 majority of cyclohexanone is 已消耗 consumed in the 生产 production of 前体 前体 precursors to 尼龙 Nylon 66 and 尼龙 Nylon 6. About 半 half of the world's 供应 supply is 已转换 converted to adipic acid, 尼龙66的两种前体之一。 one of two precursors for nylon 66. For this application, ka油（见上文）被硝酸氧化。环己酮供应的另一半转化为肟。在硫酸催化剂存在下 the KA oil (see above) is oxidized with nitric acid. The other half of the cyclohexanone supply is converted to the oxime. In the presence of sulfuric acid catalyst, 肟重排为己内酰胺 the oxime rearranges to caprolactam, 尼龙6的前体 a precursor to nylon 6: ; 然而 however , 那里 t这里 here were 胚胎毒性 embryo有毒的 toxic 效果 effects and 影响 influence on 再生产 re生产 production Cyclohexanone is 好 well 被吸收 absorbed 通过 through the skin 皮, 呼吸道 respiratory tract, and 饮食的 alimentary 道 tract. The main 新陈代谢 metabolic 通路 pathway 线索 leads to cyclohexanol, which is excreted in 尿 urine 耦合的 coupled with 葡萄糖醛酸 glucuronic acid. A 高 high 相关性 correlation was 发现 found between the 浓度 concentration of cyclohexanone in the 工作中 working 环境 environment and its 浓度 concentration in 尿 urine. Cyclohexanone is 形成的 formed from the hydrocarbons cyclohexane and 1-, 2-, and 3-hexanol. A patient's 案件 case report documents the 发展 development of 榆绿木 anosmia (an 嗅觉的 olfactory 紊乱 disorder) and 鼻炎 rhinitis 造成 ca用过的 used by by 职业的 occupational 接触 经验值 exposure to organic 溶剂 solvents, 包括环己酮 including cyclohexanone (PMID: 10476412, 16925936, 16477465）；然而 16477465); however, 这些 these 工 workers were 也 also 裸露 经验值 exposed to other compounds. 肝的 Hepatic 失调 紊乱 disorders were 发现 found in a group of 工 workers 裸露 经验值 exposed for 过度 over 五 five 年份 years. In animals, cyclohexanone is 特色的 characterized by by 相对 relatively 低 low 急性 acute 毒性 有毒的 toxicity (DL50 by by 胃内 intragastric 管理 administration is 大约 approx. 2 g/kg kg body wt.). 效果 Effects on the 中央 central 紧张 nervous system (cns CNS) were 发现 found (麻醉 narcosis), as 好 well as 刺激 irritation of the 眼睛 眼睛 eyes and skin 皮. 以下 Fol低 lowing multiple 管理 administration, 在cns中发现了影响 effects were found in the CNS, 肝 liver, and 肾脏 kidneys as 好 well as 刺激 irritation of the 结膜 conjunctiva. 诱变的 诱变剂 Mutagenic and 遗传毒性 geno有毒的 toxic 效果 effects were 发现 found, 但未发现致畸作用 but no teratogenic effects were detected