已发布 PubMed:对氧磷酶1的新型化学发光底物具有更高的特异性 New Chemiluminescent Substrates of Paraoxonase 1 with Improved Specificity: 合成和性能。 Synthesis and Properties. |
已发布 PubMed:体外评估a549细胞系中的3-芳基香豆素衍生物。 In vitro evaluation of 3-arylcoumarin derivatives in A549 cell line. |
已发布 PubMed:dft电子结构计算 DFT electronic structure calculations, 光谱研究 spectroscopic studies, 和[2-((5-硝基-1) and normal coordinate analysis of 2-[(5-nitro-1,3-噻唑-2-基)氨基甲酰基]乙酸苯酯。 3-thiazol-2-yl)carbamoyl]phenyl acetate. |
已发布 PubMed:乙酸苯酯衍生物 Phenyl acetate derivatives, 在苯基上被氟取代 fluorine-substituted on the phenyl group, 作为快速恢复的催眠药,具有反射抑制作用。 as rapid recovery hypnotic agents with reflex depression. |
已发布 PubMed:内生假心音vuk-10从红树林沉积物中产生的生物活性代谢物 Bioactive Metabolites Produced by Pseudonocardia endophytica VUK-10 from Mangrove Sediments: 隔离 Isolation, 化学结构测定和生物活性。 Chemical Structure determination and Bioactivity. |
已发布 PubMed:西斯特金 Westerdijkin A, 一种来自深海真菌西门曲霉05233的新的羟苯基乙酸衍生物。 a new hydroxyphenylacetic acid derivative from deep sea fungus Aspergillus westerdijkiae SCSIO 05233. |
已发布 PubMed:兰花car的水蒸馏和提取叶的挥发性成分的组成特征及其对食源性病原体的抗菌活性。 Profile of volatile components of hydrodistilled and extracted leaves of Jacaranda acutifolia and their antimicrobial activity against foodborne pathogens. |
已发布 PubMed:通过溶剂动力学同位素效应和四面体反应中间体的基于膦酸酯的等构类似物探索对氧磷酶-1的芳基酯酶催化作用。 Exploring the aryl esterase catalysis of paraoxonase-1 through solvent kinetic isotope effects and phosphonate-based isosteric analogues of the tetrahedral reaction intermediate. |
已发布 PubMed:[每天服用一次100 mg西他沙星的安全性和有效性的研究-使用结果调查的结果]。 [Study on the safety and efficacy of sitafloxacin at a dose of 100 mg once a day--results of the use-results survey]. |
已发布 PubMed:美国密西西比州 群中的对氧磷酶1多态性可能是与疾病易感性相关的酶活性的生物标记。 Paraoxonase 1 polymorphisms within a Mississippi USA population as possible biomarkers of enzyme activities associated with disease susceptibility. |
已发布 PubMed:磺酰胺衍生物的合成及其与牛血清白蛋白相互作用的研究 Study on the synthesis of sulfonamide derivatives and their interaction with bovine serum albumin. |
已发布 PubMed:瑞士黑中对氧磷酶1(pon1)的纯化和表征 Purification and characterization of paraoxonase 1 (PON1) from Swiss Black, 荷斯坦 Holstein, 和蒙托丰牛。 and Montofon bovines. |
已发布 PubMed:2-(5-甲基-1 2-(5-Methyl-1,3,乙酸4-氧杂二唑-2-基)苯酯。 4-oxa-diazol-2-yl)phenyl acetate. |
已发布 PubMed:植物乳杆菌中对葡萄酒酯有活性的通用芳基酯酶的表征 Characterization of a versatile arylesterase from Lactobacillus plantarum active on wine esters. |
已发布 PubMed:通过用离子聚合物物理包被来改善固定化的卵磷脂酶的催化性能。 Improving the catalytic properties of immobilized Lecitase via physical coating with ionic polymers. |
已发布 PubMed:氟取代的乙酸苯酯衍生物作为超短恢复镇静/催眠药的合成和评价。 Synthesis and evaluation of fluorine-substituted phenyl acetate derivatives as ultra-short recovery sedative/hypnotic agents. |
已发布 PubMed:对氧磷酶1在冠状动脉搭桥术中的预后价值。 Prognostic value of paraoxonase 1 in patients undergoing coronary artery bypass grafting surgery. |
已发布 PubMed:碳纤维/环氧树脂界面的自主修复。 Autonomic healing of carbon fiber/epoxy interfaces. |
已发布 PubMed:乙酸2-异丙基-4-甲基-氧基-5-甲基-苯酯。 2-Isopropyl-4-meth-oxy-5-methyl-phenyl acetate. |
已发布 PubMed:四(μ-2-苯基-乙酰基-κ(2)o Tetra-kis(μ-2-phenyl-acetato-κ(2) O:O')bis- bis-{ bis- bis-{[4-(二甲基氨基 di- di-methyl-氨基 -氨基 amino)-吡啶-κn -pyridine-κN (1)]钴 cobalt(II)}. |
已发布 PubMed:基于狄尔斯-阿尔德反应的室温自修复热固性树脂。 Room temperature self-healing thermoset based on the Diels-Alder reaction. |
已发布 PubMed:胆碱酯酶和对氧磷酶1活性之间的相关性 Correlation between Cholinesterase and Paraoxonase 1 Activities:农药中毒案件系列丛书。 Case Series of Pesticide Poisoning Subjects. |
已发布 PubMed:乙酸4-{(e)-[2-(吡啶-3-基碳基)肼基-亚甲基]甲基-基}乙酸苯酯。 4-{(E)-[2-(Pyridin-3-ylcarbon-yl)hydrazinyl-idene]meth-yl}phenyl acetate. |
已发布 PubMed:与 血清芳基酯酶/对氧磷酶结合和催化的温度依赖性。 Temperature dependence of binding and catalysis for human serum arylesterase/paraoxonase. |
已发布 PubMed:阳离子聚[双-(μ3-2-苯基-乙酰基-κ(3)o catena-Poly[bis-(μ3-2-phenyl-acetato-κ(3) O,O':o)双-(μ2-2-苯基乙酰基-κ(2)o O)bis-(μ2-2-phenyl-acetato-κ(2) O:O')双铜 di铜 copper(II)(cu-cu Cu-Cu)]. |
已发布 PubMed:营养补充剂alanerv®对急性中风后患者血清pon1活性的影响。 Effect of the nutritional supplement ALAnerv® on the serum PON1 activity in post-acute stroke patients. |
已发布 PubMed:无毒底物对硝基苯乙酸酯测定对氧磷酶1的q192r多态性。 The determination of Q192R polymorphism of paraoxonase 1 by using non-toxic substrate p-nitrophenylacetate. |
已发布 PubMed:为新的结核病呼气测试验证呼气收集和分析系统。 Validating a breath collection and analysis system for the new tuberculosis breath test. |
已发布 PubMed:乙酸2- [3-(2-乙酰氧基苯基)喹喔啉-lin-2-基]苯基。 2-[3-(2-Acetoxyphenyl)quinoxa-lin-2-yl]phenyl acetate. |
已发布 PubMed:超重和肥胖儿童和青少年的对氧磷酶(pon)-1活性 Paraoxonase (PON)-1 activity in overweight and obese children and adolescents: 与肥胖相关的炎症和氧化应激相关。 association with obesity-related inflammation and oxidative stress. |
已发布 PubMed:5-氯-2- [4-(三氟甲基)苯基氨基甲酰基]乙酸乙酸酯的振动光谱研究和计算研究。 Vibrational spectroscopic investigations and computational study of 5-chloro-2-[4-(trifluoromethyl)phenylcarbamoyl]phenyl acetate. |
已发布 PubMed: 胰岛素类似物启动治疗对2型糖尿病患者ldl / hdl亚型和高密度脂蛋白 HDL相关酶的影响 |
已发布 PubMed:高密度脂蛋白(hdl)小亚类随着前糖尿病患者中与hdl相关的磷脂酶a2活性降低而增加。 Small high-density lipoprotein (HDL) subclasses are increased with decreased activity of HDL-associated phospholipase A₂ in subjects with prediabetes. |
已发布 PubMed:硫代喹唑啉酮衍生物的合成及其抗惊厥和抗菌活性的研究。 Synthesis of some new thioxoquinazolinone derivatives and a study on their anticonvulsant and antimicrobial activities. |
已发布 PubMed:酪氨酸酶固定在改性硅藻生物二氧化硅上 Immobilization of tyrosinase on modified diatom biosilica: 从水溶液中酶促去除酚类化合物。 enzymatic removal of phenolic compounds from aqueous solution. |
已发布 PubMed:鸟氨酸苯乙酸间器官代谢(op)-一种治疗高氨血症的新策略。 Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia. |
已发布 PubMed:立体化学探测光费弗斯基重排 Stereochemically probing the photo-Favorskii rearrangement: 机械调查。 a mechanistic investigation. |
已发布 PubMed:与酒相关的乙酸细菌氧化葡糖杆菌621h的新型芳基酯酶的分子表征 Molecular characterization of a novel arylesterase from the wine-associated acetic acid bacterium Gluconobacter oxidans 621H. |
已发布 PubMed:洞察到基于2-苯基-2-(2-芳基乙酰氧基)丙二酸二乙酯的丙二酸酯基微粒体甘油三酸酯转移蛋白(mtp)抑制剂的新型水解机理。 Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor. |
已发布 PubMed:孤儿核受体nur77调节lkb1定位并激活ampk。 The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. |
已发布 PubMed:4-{[8-(4-乙酰氧基苯甲酰基)-2 4-{[8-(4-Acetyl-oxybenzo-yl)-2,乙酸7-二甲基-氧-萘-1-基]碳-基}苯基。 7-dimeth-oxy-naphthalen-1-yl]carbon-yl}phenyl acetate. |
已发布 PubMed:米托蒽醌治疗期间多发性硬化患者的对氧磷酶1活性。 Paraoxonase 1 activity in multiple sclerosis patients during mitoxantrone therapy. |
已发布 PubMed:果糖喂养的胰岛素抵抗大鼠体内盐超载会降低对氧磷酶-1的活性。 Salt overload in fructose-fed insulin-resistant rats decreases paraoxonase-1 activity. |
已发布 PubMed:微量元素对挥发性脂肪酸降解效率的影响 Impact of trace element addition on degradation efficiency of volatile fatty acids, 油酸和乙酸苯酯以及沼气池中的微生物种群。 oleic acid and phenyl acetate and on microbial populations in a biogas digester. |
已发布 PubMed:非结构基因与对氧磷酶活性的新型关联。 Novel associations of nonstructural Loci with paraoxonase activity. |
已发布 PubMed:伊朗非醇性脂肪肝患者的血清对氧磷酶和芳基酯酶活性 Serum paraoxonase and arylesterase activities in Iranian patients with nonalcoholic fatty liver disease. |
已发布 PubMed:巴基斯坦产黄青霉的野生分离株生产青霉素。 Penicillin production by wild isolates of Penicillium chrysogenum in Pakistan. |
已发布 PubMed:非甾体类抗炎药的毒性 Toxicity of non-steroidal anti-inflammatory drugs: 褪黑激素和双氯芬酸钠的关联性综述。 a review of melatonin and diclofenac sodium association. |
已发布 PubMed:乙酸4-[((e)-(3-氯-4-甲基-苯基)亚氨基-甲基-基] -2-甲氧基-3-硝基-苯基乙酸酯。 4-[(E)-(3-Chloro-4-methyl-phen-yl)imino-meth-yl]-2-methoxy-3-nitro-phenyl acetate. |
已发布 PubMed: 评估用于测量血清pon 芳基酯酶 芳基 aryl酯酶 esterase活性的新底物。 |
已发布 PubMed:2-Cyano-N'-[1-(2-hy-droxy-phen-yl)亚ethyl-idene]乙酰肼 acetohydrazide monohyd率 rate. |
已发布 PubMed:分光光度法测定狗中血清对氧磷酶1型的有效性。 Validation of spectrophotometric assays for serum paraoxonase type-1 measurement in dogs. |
已发布 PubMed:{4-二甲基 Dimethyl-氨基 -氨基 amino-N'-[1-(2-oxidophen-yl)亚ethyl-idene]苯并肼基} benzohydrazidato}(甲醇拉托 methano-lato)氧化钒 oxidovanadium(V). |
已发布 PubMed:基于结构的设计 Structure-based design, 吡唑的合成及生物学评价 synthesis and biological evaluation of N-pyrazole, N'-thiazole 尿素 urea 抑制剂 抑制剂 inhibitors of 地图 MAP 激酶 kinase p38α. |
已发布 PubMed:双(μ-2-苯基乙酰基-κo Bis(μ-2-phenyl-acetato-κO: o)bis- bis-[(2 ,2'-bipyridyl-κN,N')(2-苯基乙酰基-κo -苯乙酸钾 phenyl-乙酰-κo -乙酰基 acetato-κo -κo κO)铜 copper(II)] 二水合物 dihyd率 rate. |
已发布 PubMed:一个新的碳水化合物酯酶家族以来自嗜热地热芽孢杆菌的gdsl水解酶/乙酰木聚糖酯酶为代表。 A new family of carbohydrate esterases is represented by a GDSL hydrolase/acetylxylan esterase from Geobacillus stearothermophilus. |
已发布 PubMed:南方 群中 对氧磷酶-1血清活性和基因型与动脉粥样硬化的关系 Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep South. |
已发布 PubMed:稀释对高密度脂蛋白相关对氧磷酶-1活性的影响。 Effect of dilution on high-density lipoprotein associated paraoxonase-1 activity. |
已发布 PubMed:(2-乙酰基-酚基)(2- {1- [2-(吗啉-4-基)乙基-亚氨基]-乙基-基}酚基)(硫代氰基-κn)-钴(iii)。 (2-Acetyl-phenolato)(2-{1-[2-(morpholin-4-yl)ethyl-imino]-eth-yl}phenolato)(thio-cyanato-κN)-cobalt(III). |
已发布 PubMed:(e)-4-{[2-(2-呋喃碳基)肼基-亚甲基]甲基} -2-甲基-氧-苯基乙酸酯。 (E)-4-{[2-(2-Furylcarbon-yl)hydrazinyl-idene]meth-yl}-2-meth-oxy-phenyl acetate. |
已发布 PubMed:新乙酰氧基香豆素衍生物在癌细胞系中的细胞毒活性。 Cytotoxic activity of new acetoxycoumarin derivatives in cancer cell lines. |
已发布 PubMed:新水杨酰苯胺衍生物的抗熊果活性。 Antistaphylococcal activity of novel salicylanilide derivatives. |
已发布 PubMed:山羊小酸模/羊酸模/红酸模内容物的新型sgnh芳基酯酶的分子克隆和表征。 Molecular cloning and characterization of a novel SGNH arylesterase from the goat rumen contents. |
已发布 PubMed:[μ-2-(4-羟基-苯基)乙酰基]-κo [μ-2-(4-Hy-droxy-phen-yl)acetato]-κO:O,O';κo κO,O':O'-bis- bis- -bis- bis-{ bis- bis-{水色 aqua-(4,4'-bi-吡啶-κn -pyridine-κN)bis- bis-[2-(4-hy-droxy-phen-yl)乙酰基 acetato-κo -κo κO,O']钬 holmium(iii III)} mono-hyd率 rate. |
已发布 PubMed:aba叶化学成分的研究 Studies on the chemical constituents of Anabasis aphylla L. |
已发布 PubMed:[¹¹c]双氯芬酸钠 [¹¹C]diclofenac sodium: 皮渗透的合成和宠物评估。 synthesis and PET assessment of transdermal penetration. |
已发布 PubMed: 两种新的间苯二酚衍生物均具有从茶树ardisia brevicaulis brevicaulis diels的根产生的强大的细胞毒性。 |
已发布 PubMed:纯化的 血清(192)q和(192)r pon1同工酶对高半胱氨酸硫代内酯的不同水解作用 Differential hydrolysis of homocysteine thiolactone by purified human serum (192)Q and (192)R PON1 isoenzymes. |
已发布 PubMed:基于羟基桥接双核[cu(oh)2cu]单元的新的cu(ii)配合物 New Cu(II) complexes based on the hydroxo-bridged dinuclear [Cu(OH)2Cu] units: [cu(oh)2cu]单元的阶梯状二聚和三聚。 step-like di- and trimerizations of [Cu(OH)2Cu] units. |
已发布 PubMed:血清对氧磷酶活性与pon基因簇中的变体和老年痴呆症的风险有关。 Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. |
已发布 PubMed:一种反相hplc方法,用于分离2- [4-(甲基磺酰基)苯基] -3-(3(r)-氧代环戊基)丙酸两个立体异构体。 A reverse phase HPLC method for the separation of two stereo isomers of 2-[4-(methylsulfonyl)phenyl]-3-(3(R)-oxocyclopentyl)propanoic acid. |
已发布 PubMed:通过包封在水溶性金属笼中进行亲脂性吡啶基衍生物的药物递送。 Drug delivery of lipophilic pyrenyl derivatives by encapsulation in a water soluble metalla-cage. |
已发布 PubMed:亚烷基和亚芳基二乙酸酯与亚烷基和亚芳基二苯基二碳酸酯的熔融相交换反应合成聚碳酸酯并进行表征。 Synthesis and characterization of polycarbonates by melt phase interchange reactions of alkylene and arylene diacetates with alkylene and arylene diphenyl dicarbonates. |
已发布 PubMed:格列美脲和格列本脲对过氧化物酶1和血小板活化因子乙酰水解酶活性的区分作用。 The differentiating effect of glimepiride and glibenclamide on paraoxonase 1 and platelet-activating factor acetylohydrolase activity. |
已发布 PubMed:兔肝对氧磷酶的纯化和动力学性质1。 Purification and kinetic properties of rabbit liver paraoxonase 1. |
已发布 PubMed:化学探针的开发 Development of chemical probes: 朝向亚甲基连接的二(乙酸芳基酯)e1的作用方式。 toward the mode of action of a methylene-linked di(aryl acetate) E1. |
已发布 PubMed:合成4 Synthesis of 4', 7-diacetoxya猪 pigenin及其在 类hep g2细胞中的凋亡诱导。 |
已发布 PubMed:口服生物利用度 Oral bioavailability, p2626的疗效和胃耐受性 efficacy and gastric tolerability of P2026, 一种新型的释放一氧化氮的双氯芬酸。 a novel nitric oxide-releasing diclofenac in rat. |
已发布 PubMed:用于体内和体外激活核孤儿受体nur77的独特药效基团。 A unique pharmacophore for activation of the nuclear orphan receptor Nur77 in vivo and in vitro. |
已发布 PubMed:含苯并呋喃聚糖部分的新型一氧化氮释放双氯芬酸衍生物的合成和药理学表征。 Synthesis and pharmacological characterization of a novel nitric oxide-releasing diclofenac derivative containing a benzofuroxan moiety. |
已发布 PubMed:毛滴虫幼虫中表达的功能性 对氧磷酶-1的纯化和鉴定。 Purification and characterization of functional human paraoxonase-1 expressed in Trichoplusia ni larvae. |
已发布 PubMed:通过对配体形式的gly74cys / cys188ser突变体进行结构分析,揭示了转化丙二酸芳基酯脱羧酶对映选择性的结构基础。 Structural basis for inverting the enantioselectivity of arylmalonate decarboxylase revealed by the structural analysis of the Gly74Cys/Cys188Ser mutant in the liganded form. |
已发布 PubMed:4-氨基甲酰基哌啶乙酸苯酯半水合物。 4-Carbamoylpiperidinium phenyl-acetate hemihydrate. |
已发布 PubMed:3-乙基2-甲基8-溴-2-苯基-1 3-Ethyl 2-methyl 8-bromo-2-phenyl-1,2,3,3a 3a,4,9b-六氢铬色素[4 9b-hexa-hydro-chromeno[4,3-b]吡咯-2 3-b]pyrrole-2,3-二羧酸酯。 3-dicarboxyl-ate. |
已发布 PubMed:四基[μ-2-(4-羟基-苯基)-乙酰基]-κo Tetra-kis[μ-2-(4-hy-droxy-phenyl)-acetato]-κO,O':o;κo O;κO:O,O'-bis- bis- -bis- bis-{ bis- bis-{水色 aqua-(4,4'-bi-吡啶-κn -pyridine-κN)bis- bis-[2-(4-hy-droxy-phenyl)-乙酰-κo -乙酰基 acetato-κo -κo κO,ne(iii)}一水合物。 O]neodymium(III)} monohydrate. |
已发布 PubMed:2-苯基乙酸胍。 Guanidinium 2-phenyl-acetate. |
已发布 PubMed: 链多聚[[[[((2-苯基-乙酰基-κo)锌 zinc(ii)] bis- bis- [μ-4 ,4'-(二硫二基 disulfanedi- di-yl)二吡啶-κn dipyridine-κN:N']] monohyd率 rate]. |
已发布 PubMed:二氢杨梅素六乙酸盐。 Dihydro-myricetin hexa-acetate. |
已发布 PubMed:四-kis(μ-3 Tetra-kis(μ-3,4-二甲氧基-苯基-乙酰基)-双-((3 4-dimeth-oxy-phenyl-acetato)-bis-[(3,4-二甲氧基苯乙酸酯)(1 4-dimeth-oxy-phenyl-acetato)(1,10-菲咯啉)(iii)]。 10-phenanthroline)holmium(III)]. |
已发布 PubMed:2- [4-乙酰基-5-(联苯-4-基)-4 2-[4-Acetyl-5-(biphenyl-4-yl)-4,5-二氢-1 5-dihydro-1,3,乙酸4-恶二唑-2-基]苯基酯。 4-oxadiazol-2-yl]phenyl acetate. |
已发布 PubMed:链多聚[[[[水-[(2-羟基-苯甲酰基)乙酰基-κo catena-Poly[[[aqua-[(2-hydroxy-phen-yl)acetato-κO,O']lead(II)]-μ(3)-[(2-hydroxy-phen-yl)乙酰基 acetato-κo -κo κO:O,O':O']] monohyd率 rate]. |
已发布 PubMed:4-{[((4z)-5-oxo-2-phenyl-4 4-{[(4Z)-5-Oxo-2-phenyl-4,5-二氢-1 5-dihydro-1,乙酸3-恶唑-4-基-亚乙基]甲基-苯基酯。 3-oxazol-4-yl-idene]meth-yl}phenyl acetate. |
已发布 PubMed:八-(2-氯-苯甲基)二-μ(2)-羟基-二-μ(3)-氧化-双-(2-苯基-乙酰基)四锡(iv)。 Octa-kis(2-chloro-benz-yl)di-μ(2)-hydroxido-di-μ(3)-oxido-bis-(2-phenyl-acetato)tetra-tin(IV). |
已发布 PubMed:乙酸3-(4-(苯并[d]噻唑-2-基)-1-苯基-1h-吡唑-3-基)苯乙酸通过ros介导的途径诱导hep g2细胞凋亡。 3-(4-(Benzo[d]thiazol-2-yl)-1-phenyl-1H-pyrazol-3-yl) phenyl acetate induced Hep G2 cell apoptosis through a ROS-mediated pathway. |
已发布 PubMed:高 High 分子量 分子 molecular-重量 weight 明胶酶 gelatinase 种类 species of 的 human br Bruch's membrane: 成分分析和与年龄相关的变化。 compositional analyses and age-related changes. |
已发布 PubMed:胆固醇共轭磁性纳米粒子的合成以纯化 对氧磷酶1。 Synthesis of cholesterol-conjugated magnetic nanoparticles for purification of human paraoxonase 1. |
已发布 PubMed:冠心病患者低血清对氧磷酶-1的高患病率。 High prevalence of low serum paraoxonase-1 in subjects with coronary artery disease. |
已发布 PubMed:二氯卡宾的溶剂化 Solvation of dichlorocarbene: 与芳基醚络合。 complexation with aryl ethers. |
已发布 PubMed: 类和嵌合重组哺乳动物对氧磷酶-1酶之间有机磷水解酶活性的巨大差异。 Dramatic differences in organophosphorus hydrolase activity between human and chimeric recombinant mammalian paraoxonase-1 enzymes. |
已发布 PubMed:对氧磷酶1(pon1)的种族差异 Racial differences in paraoxonase-1 (PON1): 南方 健康的一个因素? a factor in the health of southerners? |
已发布 PubMed:分子2- [5-(2-氯乙基)-2-乙酰氧基-苄基] -4-(2-氯乙基)-乙酸苯基酯通过癌细胞中的jnk激活抑制雷帕霉素信号传导的磷酸肌醇3-激酶/ akt /哺乳动物靶标。 The novel molecule 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate inhibits phosphoinositide 3-kinase/Akt/mammalian target of rapamycin signalling through JNK activation in cancer cells. |
已发布 PubMed:乙酰氧基苯羟基 Acetoxybenzhydrols as 高度 高 highly 活性 active and 稳定 stable 类似物 类比 analogues of 1'S-1'-acetoxychavicol, 一种来自高良姜的强效抗过敏药。 a potent antiallergic principal from Alpinia galanga. |
已发布 PubMed:从宏观水平到示踪剂放射化学水平的溴化 Bromination from the macroscopic level to the tracer radiochemical level: (76)br通过亲电取代对芳香族化合物进行放射性标记。 (76)Br radiolabeling of aromatic compounds via electrophilic substitution. |
已发布 PubMed:补骨脂素的全合成 Total synthesis of psoralidin, 抗癌天然产物。 an anticancer natural product. |
已发布 PubMed:ft-ir FT-IR, 4-氯-2-(3的ft-拉曼和dft计算 FT-Raman and DFT calculations of 4-chloro-2-(3,乙酸4-二氯苯基氨基甲酰基)苯酯。 4-dichlorophenylcarbamoyl)phenyl acetate. |
已发布 PubMed:2- [3-乙酰基-5-(2-氯-3-吡啶基)-2-甲基-2 2-[3-Acetyl-5-(2-chloro-3-pyrid-yl)-2-methyl-2,3-dihydro-1,3,4-恶二唑-2-基] -4-氟-乙酸苯酯。 4-oxadiazol-2-yl]-4-fluoro-phenyl acetate. |
已发布 PubMed:4-乙酰氨基-3-硝基-苯基乙酸酯。 4-Acetamido-3-nitro-phenyl acetate. |
已发布 PubMed:3-[(e)-2-(5 3-[(E)-2-(5,7-二氯-8-羟基喹啉-2-基)乙烯基--4-羟基苯乙酸酯。 7-Dichloro-8-hydroxy-quinolin-2-yl)vin-yl]-4-hydroxy-phenyl acetate. |
已发布 PubMed:四-kis(μ(2)-3 Tetra-kis(μ(2)-3,4-二甲氧基-苯基-乙酰基)-κo 4-dimethoxy-phenyl-acetato)-κO,O':O';κo κO:O:O';κo κO:O';κo κO:O'-bis- bis- -bis- bis-[(3,4-二甲氧基-苯基-乙酰基-κo 4-dimethoxy-phenyl-acetato-κO,O')(1,10-菲咯啉-κn 10-phenanthroline-κN,n)th(iii)]。 N)thulium(III)]. |
已发布 PubMed:手性马来酰亚胺的环加成产物 A cycloaddition product of a chiral maleimide: 4-{(3a 3as * ,6as *)-4 6aS*)-4,6-二氧代-1-苯基-5-[(1r)-1-苯基-乙基] -1 6-dioxo-1-phenyl-5-[(1R)-1-phenyl-ethyl]-1,3a 3a,4,5,6,6a-六氢吡咯[3 6a-hexa-hydro-pyrrolo[3,4-c]吡唑-3-基}乙酸苯酯。 4-c]pyrazol-3-yl}phenyl acetate. |
已发布 PubMed:四(μ(2)-苯基乙酰基-κo Tetra-kis(μ(2)-phenyl-acetato-κO:O')bis- bis-[(异喹啉 isoquinoline-κN)铜 copper(II)]. |
已发布 PubMed:三甲基5-(2-氯-4-氟-苯基)-2-苯基-吡咯烷-2 Trimethyl 5-(2-chloro-4-fluoro-phen-yl)-2-phenyl-pyrrolidine-2,3,4-三羧酸酯。 4-tricarboxyl-ate. |
已发布 PubMed:4-[(2-甲基-5-氧-4 4-[(2-Methyl-5-oxo-4,5-二氢-1 5-dihydro-1,乙酸3-恶唑-4-基-亚乙基)甲基-苯基酯。 3-oxazol-4-yl-idene)meth-yl]phenyl acetate. |
已发布 PubMed:对氧磷酶(pon1 Paraoxonases (PON1, 桥2 PON2, pon3)在体外和体内分析与心血管疾病有关的信息。 PON3) analyses in vitro and in vivo in relation to cardiovascular diseases. |
已发布 PubMed:决定 类血清对氧磷酶活性变化的因素。 Determinants of variation in human serum paraoxonase activity. |
已发布 PubMed: 来自古细菌solopolic 狼尾草 solfataricus p1的新型耐高温芳基酯酶 : 纯化 purification, 表征 characterization, 和表达。 and expression. |
已发布 PubMed:对氧磷酶1在不同类型的多发性硬化症中的活性。 Paraoxonase 1 activity in different types of multiple sclerosis. |
已发布 PubMed:某些乙酰基酯和乙酰胺对组蛋白h1糖基化的抑制作用。 Inhibitory effect of some acetyl esters and acetamides on glycation of the histone H1. |
已发布 PubMed:预测有机分子的反应性。乙酸苯酯氨解的理论和实验研究。 Predicting reactivities of organic molecules. Theoretical and experimental studies on the aminolysis of phenyl acetates. |
已发布 PubMed:c20orf3编码的新型蛋白质的定位和表征。 Localization and characterization of the novel protein encoded by C20orf3. |
已发布 PubMed:高血浆c反应蛋白(crp)与2型糖尿病中的低瘦素和低脂连蛋白无关地与低对氧磷酶-i(pon-i)活性有关。 High plasma C-reactive protein (CRP) is related to low paraoxonase-I (PON-I) activity independently of high leptin and low adiponectin in type 2 diabetes mellitus. |
已发布 PubMed:乙酸3-氢氧基-4-硝基苯酯。 3-Hydr-oxy-4-nitro-phenyl acetate. |
已发布 PubMed:甲基2- [2-(2 Methyl 2-[2-(2,6-二氯苯胺基-苯基]-乙酸盐。 6-dichloro-anilino)-phenyl]-acetate. |
已发布 PubMed:聚[钾-μ-2-[2-(羧甲基)苯基]乙酰基]。 Poly[potassium-μ-2-[2-(carboxymethyl)phenyl]acetato]. |
已发布 PubMed:(s)-n-[(1s (S)-N-[(1S,2s)-2-苄基氨基-1-(4-羟基苯氧基)-3-甲基丁基] -1 2S)-2-Benzyl-amino-1-(4-hy-droxy-phen-yl)-3-methyl-butyl]-1,1-二甲基乙烷-2-亚磺酰胺。 1-di-methyl-ethane-2-sulfinamide. |
已发布 PubMed: bis(1 ,10-菲咯啉-κn 10-phenanthroline-κN,N')(苯乙酸钾 phenyl-乙酰-κo -乙酰基 acetato-κo -κo κO)铜 copper(II) phenyl-acetate 六水合物 hexa-hyd率 rate. |
已发布 PubMed:(e)-2-甲基-氧基-4-(3-氧代丁-1-烯基)乙酸苯酯。 (E)-2-Meth-oxy-4-(3-oxobut-1-en-yl)phenyl acetate. |
已发布 PubMed:乙酸4-(7-乙酰氧基-6-甲基氧基-4-甲基-2-氧代-2h-铬-3-基)苯基乙酸酯。 4-(7-Acet-oxy-6-meth-oxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate. |
已发布 PubMed:(z)-2-(2-氯-3 (Z)-2-(2-Chloro-3,3,3-三氟-丙-1-烯基)-6-甲氧基-苯基乙酸酯。 3-trifluoro-prop-1-en-yl)-6-methoxy-phenyl acetate. |
已发布 PubMed:二甲基6h Dimethyl 6H,12h-5 12H-5,11-甲基二苯并[b 11-methano-dibenzo[b,f] [1 f][1,5] diazo-cine-2 5]diazo-cine-2,8-二乙酸酯。 8-diacetate. |
已发布 PubMed:4-硝基-苯基乙酸乙酯。 Ethyl 4-nitro-phenyl-acetate. |
已发布 PubMed: 两种来自ardisia punctata lindl的新型化合物。 |
已发布 PubMed:单剂量环磷酰胺后可增加大鼠肝脏中的谷胱甘肽水平和pon1(乙酸苯酯酶)活性 Increased glutathione levels and activity of PON1 (phenyl acetate esterase) in the liver of rats after a single dose of cyclophosphamide: 防御机制? a defense mechanism? |
已发布 PubMed:[14c]乙酸苄酯是用于测量大鼠大脑中橙花胶质代谢的潜在放射性示踪剂。 [14C]Benzyl acetate is a potential radiotracer for the measurement of glial metabolism in the rat brain. |
已发布 PubMed:撤销 WITHDRAWN: 单次服用环磷酰胺后,大鼠肝脏中的谷胱甘肽水平和pon(1)(乙酸苯酯酯酶)活性增加;防御机制? Increased glutathione levels and activity of PON(1) (phenyl acetate esterase) in the liver of rats after a single dose of cyclophosphamide; a defense mechanism? |
已发布 PubMed:苯酚的生物可逆衍生物。 2.具有脂肪酸样结构的碳酸酯对水溶液中的水解反应性。 Bioreversible derivatives of phenol. 2. Reactivity of carbonate esters with fatty acid-like structures towards hydrolysis in aqueous solutions. |
已发布 PubMed:纯化和稳定 血清对氧磷酶-1的简单程序。 Simple procedures for purification and stabilization of human serum paraoxonase-1. |
已发布 PubMed:系统性红斑 患者的对氧磷酶1活性降低是动脉粥样硬化的风险。 Reduced paraoxonase1 activity is a risk for atherosclerosis in patients with systemic lupus erythematosus. |
已发布 PubMed:小型猪皮肤中酯酶的分布。 The distribution of esterases in the skin of the minipig. |
已发布 PubMed:纳米结构的生物传感器,用于测量橙花病靶标酯酶活性。 Nanostructured biosensor for measuring neuropathy target esterase activity. |
已发布 PubMed:2-乙酰基肼基-2-苯基乙酸乙酯。 Ethyl 2-acetyl-hydrazono-2-phenyl-acetate. |
已发布 PubMed:斯洛伐克语中对氧磷酶1(pon1)的活性及其与脂蛋白氧化标志物的关系。 Activity of paraoxonase 1 (PON1) and its relationship to markers of lipoprotein oxidation in healthy Slovaks. |
已发布 PubMed:从头开始研究取代基对苯基酯e和z构象异构体的相对稳定性的影响。立体电子对羰基反应性的影响。 Ab initio study of the substituent effects on the relative stability of the E and Z conformers of phenyl esters. Stereoelectronic effects on the reactivity of the carbonyl group. |
已发布 PubMed:两个异构的丁二烯-正-(乙酰氧基苯基)马来酰亚胺二尔斯-阿尔德加合物 Two isomeric butadiene-N-(acetoxyphenyl)maleimide Diels-Alder adducts: 由c-h ... x(x = o和pi)氢键和垂直偶极羰基-羰基相互作用控制的超分子结构。 supramolecular structure directed by C-H...X (X = O and pi) hydrogen bonds and perpendicular dipole carbonyl-carbonyl interactions. |
已发布 PubMed:慢性肝炎患者的血清芳基酯酶和对氧磷酶活性 Serum arylesterase and paraoxonase activity in patients with chronic hepatitis. |
已发布 PubMed:杂用氮杂-类固醇烷基化剂治疗结肠癌。 Hybrid aza-steroid alkylators in the treatment of colon cancer. |
已发布 PubMed:乳酸 Lactandrate: d-高氮-氮杂-雄甾酮烷基化剂治疗乳腺癌。 a D-homo-aza-androsterone alkylator in the treatment of breast cancer. |
已发布 PubMed:原发性高脂血症患者的颈动脉内膜中层厚度和paf-乙酰水解酶质量与活性之间缺乏关联。 Lack of association between carotid intima-media thickness and PAF-acetylhydrolase mass and activity in patients with primary hyperlipidemia. |
已发布 PubMed:铁抗坏血酸诱导的氧化应激及其在hdl和肝脏中被对氧磷酶1猝灭 Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: 与大鼠之间的比较。 comparison between humans and rats. |
已发布 PubMed:动态顶空气相色谱-嗅觉数据预测与葡萄品种有关的葡萄酒感官特性。 Prediction of the wine sensory properties related to grape variety from dynamic-headspace gas chromatography-olfactometry data. |
已发布 PubMed:设计 Design, 合成 synthesis, 和基于机理的明胶酶抑制剂的评价 and evaluation of a mechanism-based inhibitor for gelatinase A. |
已发布 PubMed:牛胃中碳酸酐酶的纯化,表征以及某些已知抑制剂对酶活性的影响。 Purification and characterization of carbonic anhydrase from bovine stomach and effects of some known inhibitors on enzyme activity. |
已发布 PubMed:气相色谱-质谱联用分析水中苯酚的方法的评价 Evaluation of a dedicated gas chromatography-mass spectrometry method for the analysis of phenols in water. |
已发布 PubMed:竞争性底物分析 血清对氧磷酶的活性位点氨基酸残基。 Analysis of active-site amino-acid residues of human serum paraoxonase using competitive substrates. |
已发布 PubMed:对氧磷酶-1(pon-1)的基因型和活性以及体内氧化的血浆低密度脂蛋白在ii型糖尿病中的作用。 Paraoxonase-1 (PON-1) genotype and activity and in vivo oxidized plasma low-density lipoprotein in Type II diabetes. |
已发布 PubMed:抗氧化剂对高脂血症大鼠血浆和组织对氧磷酶活性的影响 Differential effect of antioxidant treatment on plasma and tissue paraoxonase activity in hyperleptinemic rats. |
已发布 PubMed:提示对氧磷酶-1有助于家族性高胆固醇血症的血浆高密度脂蛋白水平。 Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia. |
已发布 PubMed:[女性腹部手术后第一天对氧磷酶活性降低]。 [Decrease of paraoxonase activity in the first day after abdominal operations in women]. |
已发布 PubMed:西西伯利亚酸性泥炭沼泽中的乙酰碎屑和氢营养型甲烷的产生和产甲烷的种群。 Acetoclastic and hydrogenotrophic methane production and methanogenic populations in an acidic West-Siberian peat bog. |
已发布 PubMed: 从dfpase-like同源模型设计的 血清对氧磷酶(h在上面 upon1)突变体的结构/功能分析。 |
已发布 PubMed:花生皮中的多酚及其清除自由基的作用。 Polyphenols from peanut skins and their free radical-scavenging effects. |
已发布 PubMed:带负电荷的脂质优先抑制 对氧磷酶1的对氧磷酶活性。 Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids. |
已发布 PubMed:荧光假单胞菌的芳基酯酶的结构。 Structure of an aryl esterase from Pseudomonas fluorescens. |
已发布 PubMed:在正和对-乙酰氧基苯基马来酰亚胺和呋喃之间的exo diels-alder加合物。 Exo Diels-Alder adducts between ortho- and para-N-acetoxyphenylmaleimides and furan. |
已发布 PubMed:钼和rh的羟基羰基配合物对有机亲电试剂的反应性。 Reactivity of molybdenum and rhenium hydroxo-carbonyl complexes toward organic electrophiles. |
已发布 PubMed:螺环吲哚啉内酯的合成。 Synthesis of a spirocyclic indoline lactone. |
已发布 PubMed:使用改良的芳基酯酶活性测定法来区分pon1(r192)与pon1(q192),以测定血清对氧磷酶/芳基酯酶活性的比率。 The ratio of serum paraoxonase/arylesterase activity using an improved assay for arylesterase activity to discriminate PON1(R192) from PON1(Q192). |
已发布 PubMed:trpv1中类香草素敏感性的分子决定因素。 Molecular determinants of vanilloid sensitivity in TRPV1. |
已发布 PubMed:3-羟基-3-甲基谷氨酰辅酶a还原酶抑制剂(他汀类药物)对组织对氧磷酶1和血浆血小板活化因子乙酰水解酶活性的影响。 Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities. |
已发布 PubMed:瘦素降低血浆对氧磷酶1(pon1)的活性并诱导氧化应激 Leptin decreases plasma paraoxonase 1 (PON1) activity and induces oxidative stress: 慢性高瘦素血症促动脉粥样硬化作用的可能新机制。 the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia. |
已发布 PubMed:3-羟基-3-甲基戊二酰辅酶a还原酶抑制剂对大鼠血浆对氧磷酶1活性的不同作用 Differential effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on plasma paraoxonase 1 activity in the rat. |
已发布 PubMed:使用底物类似物和抑制剂对 血清对氧磷酶(pon1)的构效关系。 Structure-activity relationship on human serum paraoxonase (PON1) using substrate analogues and inhibitors. |
已发布 PubMed:a 1 A 1,2,铑的4-重氮磷烷络合物。 4-diazaphospholane complex of rhodium. |
已发布 PubMed:一些新的1的合成和抗疟活性 Synthesis and antimalarial activity of some new 1,2-二氧戊环衍生物。 2-dioxolane derivatives. |
已发布 PubMed:通过将酶反应曲线拟合至集成的michaelis-menten方程来进行动态底物定量。 Kinetic substrate quantification by fitting the enzyme reaction curve to the integrated Michaelis-Menten equation. |
已发布 PubMed:金属氯化物对 血清芳基酯酶的抑制作用 Inhibition of human serum arylesterase by metal chlorides. |
已发布 PubMed:高氯化物浓度刺激 血浆对氧磷酶1(pon1)活性的物种和底物特异性刺激。 Species- and substrate-specific stimulation of human plasma paraoxonase 1 (PON1) activity by high chloride concentration. |
已发布 PubMed: 中性 neutral离子在中性ph和环境温度下催化酯的甲醇分解。 eu3 +(ch3o-)(ch3oh)x的催化参与。 |
已发布 PubMed:重组和内源性大鼠香草素受体上香草素的药理作用。 Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors. |
已发布 PubMed:快速 Fast, 简单 easy, 选择性固相清除工艺纯化酚类异构体的高效方法。 and efficient method for the purification of phenolic isomers using a selective solid-phase scavenging process. |
已发布 PubMed:观察到乙酰酯酶晶体结构中的砷加合物。 Observation of an arsenic adduct in an acetyl esterase crystal structure. |
已发布 PubMed: 过氧化物酶体增殖物激活受体α(pparα alpha)激动剂的作用 , 非诺贝特 fenofibrate, 对脂质过氧化 on lipid peroxidation, 总抗氧化能力 total antioxidant capacity, 和血浆对氧磷酶1(pon 1)活性。 and plasma paraoxonase 1 (PON 1) activity. |
已发布 PubMed:固定的乙酰胆碱酯酶检测有机磷杀虫剂-两种酶传感器的比较研究。 Detection of organophosphorus insecticides with immobilized acetylcholinesterase - comparative study of two enzyme sensors. |
已发布 PubMed:叶片/大气界面处的半挥发性有机化合物 Semi-volatile organic compounds at the leaf/atmosphere interface: 和叶片吸收的数值模拟。 numerical simulation of dispersal and foliar uptake. |
已发布 PubMed:西立伐他汀可调节大鼠血浆对氧磷酶/芳基酯酶的活性和氧化剂-抗氧化剂的平衡。 Cerivastatin modulates plasma paraoxonase/arylesterase activity and oxidant-antioxidant balance in the rat. |
已发布 PubMed:杂多酸作为薯条重排的新型有效催化剂。 Heteropoly acid as a novel efficient catalyst for Fries rearrangement. |
已发布 PubMed:对氧磷酶-1和氧化的低密度脂蛋白对2型糖尿病肾病的影响 [The effects of paraoxonase-1 and oxidized low density lipoprotein on nephropathy in type-2 diabetes mellitus]. |
已发布 PubMed:i型糖尿病的高密度脂蛋白组成和对氧磷酶活性。 High-density lipoprotein composition and paraoxonase activity in Type I diabetes. |
已发布 PubMed:积分速率方程拟合反应曲线,测定血清芳基酯酶活性 Assay of serum arylesterase activity by fitting to the reaction curve with an integrated rate equation. |
已发布 PubMed:半抗原设计的保真度 Fidelity in Hapten Design: 膦酸酯的半胱氨酸与芳基酯的碱性水解过渡态相似吗? How Analogous Are Phosphonate Haptens to the Transition States for Alkaline Hydrolyses of Aryl Esters? |
已发布 PubMed:解析磷酸与对硝基苯基硫代乙酸酯反应的亲核和一般碱作用 Dissection of Nucleophilic and General Base Roles for the Reaction of Phosphate with p-Nitrophenyl Thiolacetate, 对硝基苯硫基甲酸酯 p-Nitrophenyl Thiolformate, 和苯硫基乙酸酯。 and Phenyl Thiolacetate. |
已发布 PubMed:抗炎药。 X。水合吡咯烷鎓[2-[(2 Anti-inflammatory drugs. X. Hydrated pyrrolidinium [2-[(2,(6-二氯苯基)氨基]苯基]乙酸酯(hp.d.h2o)。 6-dichlorophenyl)amino]phenyl]acetate(HP.D.H2O). |
已发布 PubMed:阿司匹林。构象偏好和邻近基团相互作用的从头量子力学研究。 Aspirin. An ab initio quantum-mechanical study of conformational preferences and of neighboring group interactions. |
已发布 PubMed:抗炎药。 ix。水合二乙铵(2-(2 Anti-inflammatory drugs. IX. Hydrated diethylammonium (2-(2,6-二氯苯基氨基)苯基)乙酸酯(hdea.d.h2o)。 6-dichlorophenylamino)phenyl)acetate (HDEA.D.H2O). |
已发布 PubMed: 血清对氧磷酶水解血小板活化因子。 Hydrolysis of platelet-activating factor by human serum paraoxonase. |
已发布 PubMed:苯基脂肪酸抑制贫铀诱导的 体细胞肿瘤转化 Suppression of depleted uranium-induced neoplastic transformation of human cells by the phenyl fatty acid, 醋酸苯 phenyl acetate: 通过靶向p21ras蛋白途径进行化学预防。 chemoprevention by targeting the p21RAS protein pathway. |
已发布 PubMed:黄素腺嘌呤二核苷酸拜尔-维利格型单加氧酶将4-羟基苯乙酮转化为乙酸4-苯酯。 Conversion of 4-hydroxyacetophenone into 4-phenyl acetate by a flavin adenine dinucleotide-containing Baeyer-Villiger-type monooxygenase. |
已发布 PubMed:西北印第安 中的阿司匹林酯酶 Aspirin esterases in North-West Indians: 年龄和营养的影响。 the influence of age and nutrition. |
已发布 PubMed:甘油和水中的可溶性α-胰凝乳蛋白酶的特性 Properties of soluble alpha-chymotrypsin in neat glycerol and water. |
已发布 PubMed:双取代机理催化酰基转移 Catalysis of acyl group transfer by a double-displacement mechanism: calixcrown-ba2 +配合物催化芳基酯的裂解 the cleavage of aryl esters catalyzed by calixcrown-Ba2+ complexes |
已发布 PubMed:合成莫米霉素。 Synthesis of mimosamycin. |
已发布 PubMed:[苯酚生产废水的微生物降解]。 [Microbial degradation of components of waste water from phenol-producing industry]. |
已发布 PubMed:钙依赖性 血清高半胱氨酸硫内酯水解酶。对蛋白质正半胱氨酰化的保护机制。 Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation. |
已发布 PubMed:对氧磷酶(pon1)多态性它与西北印度旁遮普邦的血脂的关系。 Paraoxonase (PON1) polymorphism & its relation with lipids in north west Indian Punjabis. |
已发布 PubMed:致命性暴发性肝炎与使用溴芬酸有关。 Fatal fulminant hepatitis associated with bromfenac use. |
已发布 PubMed:兔对氧磷酶多态性。 Paraoxonase polymorphism in rabbits. |
已发布 PubMed:能够水解磷酸二异丙酯的可溶性小鼠肝脏酶的表征。 Characterization of a soluble mouse liver enzyme capable of hydrolyzing diisopropyl phosphorofluoridate. |
已发布 PubMed:水泡假单胞菌pd参与聚乙烯醇降解的酯酶的纯化和表征。 Purification and characterization of an esterase involved in poly(vinyl alcohol) degradation by Pseudomonas vesicularis PD. |
已发布 PubMed:z-(-的体内竞争研究 In vivo competition studies of Z-(-,-)-[125i] iqnp对2-喹啉环烷基2-(5-溴噻吩基)-2-噻吩基乙醇酸酯(brqnt)的体内m2毒蕈碱亚型对brqnt的选择性。 -)-[125I]IQNP against 3-quinuclidinyl 2-(5-bromothienyl)-2-thienylglycolate (BrQNT) demonstrating in vivo m2 muscarinic subtype selectivity for BrQNT. |
已发布 PubMed:慢性肾功能衰竭患者血清对氧磷酶活性降低。 Decrease of serum paraoxonase activity in chronic renal failure. |
已发布 PubMed:对氧磷酶是心血管疾病的危险标志 Paraoxonase as a risk marker for cardiovascular disease: 事实和假设。 facts and hypotheses. |
已发布 PubMed:纯化两种具有对毒死-氧肟酸和对氧磷的α-酯酶活性的大鼠肝蛋白。 Purification of two rat hepatic proteins with A-esterase activity toward chlorpyrifos-oxon and paraoxon. |
已发布 PubMed:非平衡分析改变了外围位点配体抑制乙酰胆碱酯酶的机制解释。 Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands. |
已发布 PubMed:经皮应用无毛大鼠后14c-moxisylyte的代谢 Metabolism of 14C-moxisylyte after percutaneous application in hairless rat. |
已发布 PubMed:络合剂对乙酸钡的ba(ii)辅助碱性乙醇分解的影响 Effect of Cation-Complexing Agents on the Ba(II)-Assisted Basic Ethanolysis of Phenyl Acetate: 从阳离子失活到阳离子活化 From Cation Deactivation to Cation Activation. |
已发布 PubMed:存在分支酸类似物的情况下,大肠杆菌中分支酸突变酶-苯甲酸酯脱氢酶的部分失活。 Partial inactivation of chorismate mutase-prephenate dehydrogenase from Escherichia coli in the presence of analogues of chorismate. |
已发布 PubMed:大肠杆菌的硫酯酶i具有芳基酯酶活性,并且对蛋白酶底物具有立体特异性。 The thioesterase I of Escherichia coli has arylesterase activity and shows stereospecificity for protease substrates. |
已发布 PubMed:一些环状核苷酸减轻了苯肾上腺素和佛波酯引起的大鼠肠系膜前动脉的收缩。 Some cyclic nucleotides reduce phenylephrine-induced and phorbol ester-induced constriction of the rat anterior mesenteric artery. |
已发布 PubMed:鉴定和分离出对对氧磷和毒死rif具有α-酯酶活性的两种大鼠血清蛋白。 Identification and isolation of two rat serum proteins with A-esterase activity toward paraoxon and chlorpyrifos-oxon. |
已发布 PubMed:14c-moxisylyte经皮应用于无毛大鼠后的药代动力学研究。 Pharmacokinetics study of 14C-moxisylyte after percutaneous application to hairless rat. |
已发布 PubMed:番荔枝新的相邻的双-thf壬酸产乙酸素具有新的生物活性。 New bioactive adjacent bis-THF annonaceous acetogenins from Annona bullata. |
已发布 PubMed:fasciculin 2与乙酰胆碱酯酶的外围位点结合,并通过减慢酶酰化过程中质子转移的步骤来抑制底物水解。 Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation. |
已发布 PubMed:重新考虑哺乳动物对氧磷酶/芳基酯酶的催化中心和机理。 Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase. |
已发布 PubMed:立体光刻技术在精确分子模型制造中的应用。 The application of stereolithography to the fabrication of accurate molecular models. |
已发布 PubMed:关于青霉素酰基转移酶特异性的新见解。 New insights on the specificity of penicillin acylase. |
已发布 PubMed:无毛大鼠中14c-moxisylyte的代谢。比较投注静脉和口服途径之间。 Metabolism of 14C-moxisylyte in hairless rat. Comparison between intravenous and oral route. |
已发布 PubMed:抗炎药 Anti-inflammatory drugs: 双氯芬酸1-(2-羟乙基)吡咯烷鎓盐。 1-(2-hydroxyethyl)pyrrolidinium salt of diclofenac. |
已发布 PubMed:基于机理的催化抗体失活。 Mechanism-based catalytic antibody inactivation. |
已发布 PubMed:同工酶 Isoabzymes: 相同免疫接种在结构上和机理上相似的催化抗体。 structurally and mechanistically similar catalytic antibodies from the same immunization. |
已发布 PubMed:血清生化指标评估抗肿瘤药对肾脏和肝脏的亚急性毒性 Evaluation of kidney and liver subacute toxicity of antitumor agents using serum biochemical parameters in rats. |
已发布 PubMed:体内14c标记的丙酸酯代谢以及相对于克雷布斯循环通量的肝糖异生估计。 14C-labeled propionate metabolism in vivo and estimates of hepatic gluconeogenesis relative to Krebs cycle flux. |
已发布 PubMed:抑制酯化乙酸4-硝基苯酯酶解的一种新的自动化方法,用于对芳基酯酶进行表型化(ec 3.1.1.2)。 A new automated method for phenotyping arylesterase (EC 3.1.1.2) based upon inhibition of enzymatic hydrolysis of 4-nitrophenyl acetate by phenyl acetate. |
已发布 PubMed:快速推定鉴定并进一步鉴定连翘。 Rapid presumptive identification and further characterization of Bacteroides forsythus. |
已发布 PubMed:新分离的硝酸盐还原菌对3-羟基苯甲酸酯的厌氧降解。 Anaerobic degradation of 3-hydroxybenzoate by a newly isolated nitrate-reducing bacterium. |
已发布 PubMed:酪氨酸依赖性催化抗体的机理研究。 Mechanistic studies of a tyrosine-dependent catalytic antibody. |
已发布 PubMed:[测定β-内酰胺抗生素生产过程中苯乙酸水平的快速电位测定法]。 [A potentiometric rapid method of determining the level of phenylacetic acid during the production of beta-lactam antibiotics]. |
已发布 PubMed:[用含氧水湿式氧化有毒工业废料]。 [Wet oxidation of toxic industrial waste with oxygenated water]. |
已发布 PubMed:乙酸[2-14c]的代谢及其在评估肝克雷布斯循环活性和糖异生中的应用。 Metabolism of [2-14C]acetate and its use in assessing hepatic Krebs cycle activity and gluconeogenesis. |
已发布 PubMed:肝中克雷布斯循环代谢的无创追踪。 Noninvasive tracing of Krebs cycle metabolism in liver. |
已发布 PubMed:在抗有机磷杀虫剂的蚊子中具有高的对氧磷水解活性。 High paraoxon-hydrolyzing activity in organophosphorus insecticide-resistant mosquitoes. |
已发布 PubMed:[山iso碱四种立体异构体的分离和拆分]。 [Separation and resolution of four stereo-isomers of anisodamine]. |
已发布 PubMed:使用催化抗体作为分子识别元件的电位生物传感器。 Potentiometric biosensor employing catalytic antibodies as the molecular recognition element. |
已发布 PubMed:肟诱导的有机次膦酸盐抑制的乙酰胆碱酯酶的再活化。 Oxime-induced reactivation of acetylcholinesterase inhibited by organophosphinates. |
已发布 PubMed:根据法令(ec)第13(5)条,对与葛根提取物(paullinia cupana kunth(瓜拉那))和山茶(c。kuntze)(绿茶)提取物相关的健康主张进行证实的科学意见否1924/2006查看页面或查看pdf Preparation and properties of (R)-(-)-1-azabicyclo[2.2.2]oct-3-yl- (R)-(+)-alpha-hydroxy-alpha-(4-[125I]iodophenyl)-alpha-phenyl acetate and (R)-(-)-1-azabicyclo[2.2.2]oct-3-yl-(S)-(-)-alpha-hydroxy-alpha- (4-[125I]iodophenyl)-alpha-phenyl acetate as potential radiopharmaceuticals. |
已发布 PubMed:分光光度法测定血浆对氧磷酶/芳基酯酶对毒死rif和对硫磷的活性代谢产物的酶促水解。 Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase. |
已发布 PubMed: 实验室调查了由两种不同的多重耐药性不动杆菌钙乙酸亚种引起的医院暴发。 anitratus anitratus菌株。 |
已发布 PubMed:自动化机器 提取血浆样品中的双氯芬酸并随后进行分析。 Automated robotic extraction and subsequent analysis of diclofenac in plasma samples. |
已发布 PubMed:单克隆抗体nms-1增加 嗜中性粒细胞中n-甲酰基趋化肽介导的氧化爆发的产生。 Monoclonal antibody NMS-1 increases N-formyl chemotactic peptide-mediated oxidative burst generation in human neutrophils. |
已发布 PubMed:流式细胞术改进细胞内酶反应和抑制动力学的方法。 Improved methodology for intracellular enzyme reaction and inhibition kinetics by flow cytometry. |
已发布 PubMed:结核杆菌的特征和感染部位 Characteristics and sites of infection of Eubacterium nodatum, 胆小杆菌 Eubacterium timidum, 短杆菌 Eubacterium brachy, 和其他糖酵解真细菌。 and other asaccharolytic eubacteria. |
已发布 PubMed:区别 Distinction between 'A'-酯酶 酯酶 esterases and 芳基酯酶 芳基酯酶 芳基 aryl酯酶 酯酶 esterases. 含意 Implications for 酯酶 esterase 分类 classification. |
已发布 PubMed: 褐飞虱的化学信息吸引剂怎么样 Howardi ba Barber , 南部玉米根虫 southern corn rootworm, 香根草 andDiabrotica virgifera virgifera leconte, 西部玉米根虫(鞘翅目 the western corn rootworm (Coleoptera: chrysomelidae)。 |
已发布 PubMed:兔呼吸道中的羧酸酯酶 Carboxylesterases in the respiratory tracts of rabbits, 大鼠和叙利亚仓鼠。 rats and Syrian hamsters. |
已发布 PubMed:血浆和滑液中双氯芬酸钠的体外蛋白质结合。 In vitro protein binding of diclofenac sodium in plasma and synovial fluid. |
已发布 PubMed:遍在蛋白的一级和二级结构研究其nε-乙酰化的赖氨酸衍生物。 Investigations of primary and secondary structure of porcine ubiquitin. Its N epsilon-acetylated lysine derivative. |
已发布 PubMed:在实验性苯丙酮尿症中乙酸苯酯橙花毒性的生化解释。 A biochemical explanation of phenyl acetate neurotoxicity in experimental phenylketonuria. |
已发布 PubMed:猪成熟红细胞泛素的n-ε-乙酰化。 N-epsilon-acetylation of porcine mature erythrocytes ubiquitin. |
已发布 PubMed:[125i] 4-碘苯甲酸3-奎宁环烷基 [125I] 3-quinuclidinyl 4-iodobenzilate: 高亲和力 a high affinity, m1和m2-乙酰胆碱受体的高比活度放射性配体。 high specific activity radioligand for the M1 and M2-acetylcholine receptors. |
已发布 PubMed: 3 beta-hydroxy-13 α alpha-氨基 -氨基 amino-13的抗肿瘤活性的进一步研究 , 17-seco-5 α alpha-androstan-17-oic-13 ,17-内酰胺[对[[双(2-氯乙基)氨基]-苯基]乙酸酯(nsc 290205)。 17-lactam [p-[bis(2-chloroethyl)amino]-phenyl]acetate (NSC 290205). |
已发布 PubMed:通过羧酸酯刺激外排并抑制光合作用。 Stimulation of h efflux and inhibition of photosynthesis by esters of carboxylic acids. |
已发布 PubMed:胰蛋白酶抑制剂对扎克大鼠的食物摄入和体重增加的影响。 Trypsin inhibitor effects on food intake and weight gain in Zucker rats. |
已发布 PubMed:尿乙酸苯酯 Urinary phenyl acetate: 诊断抑郁症? a diagnostic test for depression? |
已发布 PubMed:通过载体特异性异源t辅助细胞识别λ1和λ2鼠轻链; l-h链装配的效果。 Recognition of lambda 1 and lambda 2 murine light chains by carrier-specific isologous T helper cells; effect of L-H chain assembly. |
已发布 PubMed:牙髓中有害刺激物诱导的脑啡肽样肽含量的变化 Changes of the Met-enkephalin-like peptide content induced by noxious stimuli in the rat incisor pulp. |
已发布 PubMed:1-溴松果酮 1-Bromopinacolone, 乙酰胆碱酯酶的活性定点共价抑制剂。 an active site-directed covalent inhibitor for acetylcholinesterase. |
已发布 PubMed:氨基酸衍生物与二聚体α-胰凝乳蛋白酶的相互作用。 Interaction of specific amino acid derivatives with dimeric alpha-chymotrypsin. |
已发布 PubMed: 3 beta-hydroxy-13 α alpha-氨基 -氨基 amino-13的活性 , 17-seco-5 α alpha-androstane-17-oic-13 ,鼠实体瘤中的17-内酰胺(对-(双(2-氯乙基)氨基)-苯基)乙酸酯(nsc 290205)。 17-lactam(p-(bis(2-chloroethyl)amino)-phenyl) acetate(NSC 290205) in murine solid tumors. |
已发布 PubMed:鸡脑微管蛋白酪氨酸羧肽酶 Tubulinyl-tyrosine carboxypeptidase from chicken brain: 性质和部分纯化。 properties and partial purification. |
已发布 PubMed:血清中的芳基酯酶 Arylesterase in serum: 固定孵育方法的详细说明和临床应用。 elaboration and clinical application of a fixed-incubation method. |
已发布 PubMed:酸性脂肪酶的研究 Studies on acid lipase, 在 体组织中具有抗600酸酯酶活性。 and E 600-resistant acid esterase activities in human tissue homogenates. |
已发布 PubMed:雌二醇芥末的生物测定法可能的致癌性(CAS号:22966-79-6)。 Bioassay of Estradiol Mustard for Possible Carcinogenicity (CAS No. 22966-79-6). |
已发布 PubMed:胆碱酯酶抑制剂对乙酸酯对大鼠子宫的痉挛作用的影响。 Effects of cholinesterase inhibitors on the spasmogenic action of acetate esters on rat uterus. |
已发布 PubMed:抗生素渗入 。 Penetration of antibiotics into bile. |
已发布 PubMed:潜在的过渡态类似物与乙酰胆碱酯酶结合的模式。 The mode of binding of potential transition-state analogs to acetylcholinesterase. |
已发布 PubMed:抑制有机磷酸盐后,乙酰胆碱酯酶的自发激活。 ii。重新活化成分的表征。 Spontaneous reactivation of acetylcholinesterase following organophosphate inhibition. II. Characterization of the reactivating components. |
已发布 PubMed:α-胰凝乳蛋白酶催化 α-胰凝乳蛋白酶 α alpha-胰凝乳蛋白酶 chymotrypsin-催化的 catalyzed 水解 hydrolysis of 醋酸苯 phenyl acetate. 大 Large Hammett's rho rho 不变 constant and 参与 participation of 组氨酸酰化 histidine-酰基 acylated 中间 intermediate. |
已发布 PubMed:乙酸酯对回肠平滑肌的痉挛作用的一些方面。 Aspects of the spasmogenic effects of acetate esters on ileal smooth muscle. |
已发布 PubMed:胰凝乳蛋白酶被苯甲酸和乙酸苯酯酰化的机理 Mechanisms of acylation of chymotrypsin by phenyl esters of benzoic acid and acetic acid. |
已发布 PubMed:[on On the 效率 efficiency of new 消炎 antiinflammatory agents. A 比较 comparative 研究 study (author's 翻译 transl)]. |
已发布 PubMed:钠邻[[2]的定量测定 Quantitative determination of sodium-o-[(2, 血浆或血清中的6-二氯苯基)-氨基]苯基乙酸酯(双氯芬酸)。 6-dichlorophenyl)-amino]phenylacetate (diclofenac) in human blood plasma or serum. |
已发布 PubMed:乙酸吲哚苯酯和乙酰胆碱酯酶 Indophenyl acetate and acetylcholinesterase: 非特异性底物在活性中心边缘的结合。 binding of a non-specific substrate on the margin of the active center. |
已发布 PubMed:在无水乙酸中,环状和无环酸酐将苯酚酰化。 Acylation of phenol by cyclic and acyclic anhydrides in anhydrous acetic acid. |
已发布 PubMed:苯乙酮的微生物代谢。香柳叶菜杆菌物种对苯乙酮和某些氯苯乙酮的代谢。 The microbial metabolism of acetophenone. Metabolism of acetophenone and some chloroacetophenones by an Arthrobacter species. |
已发布 PubMed:乙酰胆碱酯酶催化 Catalysis by acetylcholinesterase: 有证据表明,与某些底物进行酰化反应的限速步骤先于一般的酸碱催化。 evidence that the rate-limiting step for acylation with certain substrates precedes general acid-base catalysis. |
已发布 PubMed:[微生物蛋白水解复合物中的胰凝乳蛋白酶样蛋白酶]。 [Chymotrypsin-like proteinases in microbial proteolytic complexes]. |
已发布 PubMed:马血浆中丁酰胆碱酯酶的稳态动力学模型。 A steady-state kinetic model of butyrylcholinesterase from horse plasma. |
已发布 PubMed:脂质去除对牛血浆芳基酯酶分子大小和动力学性质的影响 Effects of lipid removal on the molecular size and kinetic properties of bovine plasma arylesterase. |
已发布 PubMed:钠(o-((2 Sodium (o-((2,6-二氯苯基)-氨基)-苯基)-乙酸酯(gp 45840) 6-dichlorophenyl)-amino)-phenyl)-acetate (GP 45 840), 一种新型的非甾体类抗炎药。 a new non-steroidal anti-inflammatory agent. |
已发布 PubMed:四氯化碳从肝脏微粒体释放乙酸苯酯酶。 Release of phenyl acetate esterase from liver microsomes by carbon tetrachloride. |
已发布 PubMed:[钙和镁离子的作用 [Effect of calcium and magnesium ions, 作为ph的函数 as a function of pH, 酯酶水解乙酸苯酯的研究 on hydrolysis of phenyl acetate by erythrocyte esterases]. |
已发布 PubMed:[胆碱对乙酸苯酯作用的增强作用。 5.乙酰胆碱释放抑制剂的作用]。 [Potentiating effects of choline on the action of phenyl acetate. 5. Effects of inhibitors of acetylcholine liberation]. |
已发布 PubMed:[乙酸苯乙酸酶水解动力学]。 [Kinetics of enzymatic hydrolysis of phenyl acetate]. |
已发布 PubMed:评估乙酸苯酯酶活性作为肝脏损害的指标。 Evaluation of phenyl acetate esterase activity as an index of liver damage. |
已发布 PubMed:酯的氨解。七。赖氨酸与乙酸苯酯和三醋精的反应。 Aminolysis of esters. VII. The reaction of lysine with phenyl acetate and triacetin. |
已发布 PubMed:乙酸苯酯酶活性测定在肝功能检查中的应用 [Application of phenyl acetate esterase activity determination in liver function tests]. |
已发布 PubMed:士的宁的作用 Effects of strychnine, 乙酸苯酯和儿茶酚胺的衍生物对豚鼠回肠胆碱能橙花末梢的收缩和乙酰胆碱输出的影响。 derivatives of phenyl acetate and catecholamines on contraction and acetylcholine output from the cholinergic nerve ending of guinea pig ileum. |
已发布 PubMed:苯乙酸及其类似物对豚鼠小肠分离的影响 Effects of phenyl acetate and its analogues on isolated guinea-pig small intestine. |
已发布 PubMed:电泳分离 血清中乙酸苯酯水解酯酶。依达依赖酶的证明。 Curtain electrophoretic separation of phenyl acetate hydrolysing esterases of human serum. Demonstration of an EDTA-dependent enzyme. |
已发布 PubMed:取代基对小麦胚芽脂肪酶水解乙酸苯酯的影响。 The effect of substituents on the hydrolysis of phenyl acetate by wheat germ lipase. |
已发布 PubMed:酶作用研究 STUDIES ON ENZYME ACTION : xxxv。不同年龄兔组织提取物的脂肪酶作用 XXXV. LIPASE ACTIONS OF EXTRACTS OF TISSUES OF RABBITS AT DIFFERENT AGES. |