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Category:solvents
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 出现 Appearance: | 无色透明液体（est） colorless clear liquid (est) |
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
|
| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 熔点 Melting Point: | -25.00 °C. @ 760.00 mm 汞 Hg (est)
|
| 沸点 Boiling Point: | 202.00 °C. @ 760.00 mm 汞 Hg
|
| 蒸汽压力 Vapor Pressure: | 0.345000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) |
| 蒸气密度 Vapor Density: | 3.4 ( 空气 Air = 1 ) |
| 闪点 Flash Point: | 187.00 °F. tcc TCC ( 86.10 °C. ) (est)
|
| logp（o / w） logP (o/w): | -0.380 |
| 溶于 Soluble in: |
| | 水 water, 1.00E+06 mg/L @ 25 ＆deg °C (经验值 exp) | | | 水 water, 2.483e + 005 mg / l @ 25°c（est） 2.483e+005 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
| 乙酰苯 Aceto |
| 正甲基-2-吡咯烷酮 N-Methyl -2- pyrrolidone
|
| 共价化学 Covalent Chemical |
| 正甲基吡咯烷酮 N-methyl pyrrolidone
|
| 伊士曼化学 Eastman Chemical |
| 正甲基-2-吡咯烷酮（nmp） N-Methyl-2-Pyrrolidone (NMP)
气味 Odor: characteristic 采用 Use: n-甲基-2-吡咯烷酮（nmp）是高沸点的 N-Methyl-2-Pyrrolidone (NMP) is a high boiling, 极性质子 polar aprotic, 1-（2-羟基-4-甲氧基苯基）-1- [2-羟基-4-（甲氧基）苯基]乙酮1-（2-羟基-4-甲氧基-苯基）-乙酮2-羟基-4-甲氧基苯乙酮1-（2 -羟基-4-甲氧基苯基）乙酮1-（2-羟基-4-甲氧基苯基）乙酮2'-羟基-4'-甲氧基苯乙酮4-甲氧基-2-羟基苯乙酮4'-甲氧基-2'-羟基苯乙酮4-o-甲基苯乙酮4-o-甲基苯乙酮丹皮酚 low viscosity liquid. NMP has a good solvency for a wide range of organic and inorganic compounds and it is miscible with water at all temperatures and has a high chemical and thermal stability. It is used as a solvent for engineering polymers and coating resins. The polar nature and the low surface tension of NMP makes it also an excellent cleaning medium and paint stripping solvent. |
| Glentham Life Sciences |
| 1-Methyl-2-pyrrolidinone
|
| 利昂德尔巴塞尔工业 LyondellBasell Industries |
| 正甲基-2-吡咯烷酮 N-Methyl -2- pyrrolidone
|
| Penta International |
| 1-甲基-2-吡咯烷酮 1-METHYL-2-PYRROLIDINONE
|
| 圣克鲁斯生物技术 Santa Cruz Biotechnology |
| 仅供实验/研究使用。 For experimental / research use only. |
| 1-甲基-2-吡咯烷酮≥99％ 1-Methyl-2-pyrrolidinone ≥99%
|
| 湿婆化学药品和制药 Shiva Chemicals and Pharmaceuticals |
| 正甲基吡咯烷酮 N-methyl pyrrolidone
|
| 西格玛·奥尔德里奇 Sigma-Aldrich |
| 仅供实验/研究使用。 For experimental / research use only. |
| 无水1-甲基-2-吡咯烷酮 1-Methyl-2-pyrrolidinone anhydrous, 99.5%
|
| 银蕨化学 Silver Fern Chemical |
| 正甲基吡咯烷酮 N-methyl pyrrolidone
气味 Odor: characteristic 采用 Use: 正甲基吡咯烷酮通常用作树脂和乙炔的溶剂 N-Methylpyrrolidone is commonly used as a solvent for resins and acetylene, 颜料分散剂 a pigment dispersant, 在油中 in petroleum, 微电子学 microelectronics, 塑料制品 plastics, 纺织品 textiles, 农用化学品 agrochemicals, 和药品。 and pharmaceuticals. |
| 塔明科（伊斯曼） Taminco (Eastman) |
| n-methylpyrrolidone
|
| TCI AMERICA |
| 仅供实验/研究使用。 For experimental / research use only. |
| 1-甲基-2-吡咯烷酮> 99.0％（gc） 1-Methyl-2-pyrrolidinone >99.0%(GC)
|
| 环球防腐化学公司 Universal Preserv-A-Chem Inc. |
| 微量纯 MICROPURE EG
气味 Odor: characteristic 采用 Use: nmp用于回收加工油化工中产生的某些碳氢化合物 NMP is used to recover certain hydrocarbons generated in the processing petrochemicals, 如恢复1 such as the recovery of 1,6-dien-3-醇-芳樟醇（-）-芳樟醇（-）-b-芳樟醇（3r）-（-）-芳樟醇（减）-芳樟醇（r）-芳樟醇（r）-（-）-芳樟醇- linaloollaevo-linaloolr-linaloollaevo-linalool ex-basil（天然）laevo-linalool ex-ho木材（天然）linalool laevol-linalool naturallaevo-linalool美国 3-butadiene and acetylene. It is used to absorb hydrogen sulfide from sour gas and hydrodesulfurization facilities. Due to its good solvency properties NMP is used to dissolve a wide range of polymers. It also used as a solvent for surface treatment of textiles, resins, 以及涂有金属的塑料或作为脱漆剂。 and metal coated plastics or as a paint stripper. |
安全信息 Safety Information:
| 首选SDS Preferred SDS: 视图 View |
| |
| 危害识别 Hazards identification |
| |
| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
| |
| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
静脉狗 intravenous-dog LD50 63300 ug ug/kg
Iyakuhin 贤九 Kenkyu. 研究 Study of 医疗 Medical 商店 Supplies. 卷 Vol. 18, pg。 922 Pg. 922, 1987.
腹腔内小鼠 intraperitoneal-mouse LD50 3050 mg/kg
United 状态 States 环境的 环保 Environmental 保护 Protection 机构 Agency, 农药和有毒物质办公室。卷8ehq-1087-0695 Office of Pesticides and Toxic Substances. Vol. 8EHQ-1087-0695
静脉老鼠 intravenous-mouse LD50 54500 ug ug/kg
Iyakuhin 贤九 Kenkyu. 研究 Study of 医疗 Medical 商店 Supplies. 卷 Vol. 18, pg。 922 Pg. 922, 1987.
老鼠 oral-mouse LD50 5130 mg/kg
United 状态 States 环境的 环保 Environmental 保护 Protection 机构 Agency, 农药和有毒物质办公室。卷8ehq-1087-0695 Office of Pesticides and Toxic Substances. Vol. 8EHQ-1087-0695
腹膜内大鼠 intraperitoneal-rat LD50 2472 mg/kg
Arzneimittel-Forschung. 药品 Drug ug 研究 Research. 卷 Vol. 26, pg. 1581 Pg. 1581, 1976.
静脉内大鼠 intravenous-rat LD50 80500 ug ug/kg
Iyakuhin 贤九 Kenkyu. 研究 Study of 医疗 Medical 商店 Supplies. 卷 Vol. 18, pg。 922 Pg. 922, 1987.
口鼠 oral-rat LD50 3914 mg/kg
Arzneimittel-Forschung. 药品 Drug ug 研究 Research. 卷 Vol. 26, pg. 1581 Pg. 1581, 1976.
未报告的老鼠 unreported-rat LD50 7000 mg/kg
"Toxicology of 毒品 药品 Drug ugs and Chemicals," 德希曼 Deichmann, w.b. W.B., 纽约 New York, 学术出版社 Academic Press, 公司 Inc., 1969卷-- 1969Vol. -, pg。 408 Pg. 408, 1969.
|
| 皮肤毒性 Dermal Toxicity: |
皮肤兔子 skin-rabbit LD50 8000 mg/kg
Raw 材料 Material Data 手册 Handbook, 第1卷 Vol.1: 有机溶剂 Organic Solvents, 1974年。 1个 1974. Vol. 1, pg。 84 Pg. 84, 1974.
皮下大鼠 subcutaneous-rat LD50 > 2000 mg/kg
United 状态 States 专利 Patent 文献 Document. 卷 Vol. #4882359
|
| 吸入毒性 Inhalation Toxicity: |
吸入大鼠 inhalation-rat 克洛 LCLo 1000 mg/m3
国民 National 技术 Technical Information 服务 Service. 卷 Vol. OTS0534725
|
使用安全信息 Safety in Use Information:
| Category: | | solvents |
| 推荐的1-甲基-2-吡咯烷酮使用量最高为 Recommendation for 1-methyl-2-pyrrolidinone usage levels up to: | | | 不用于香水。 not for fragrance use.
|
| |
| 推荐的1-甲基-2-吡咯烷酮风味剂使用水平最高为 Recommendation for 1-methyl-2-pyrrolidinone flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
|
安全参考 Safety references:
参考资料 References:
| | 1-甲基吡咯烷-2-酮 1-methylpyrrolidin-2-one |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 872-50-4 |
| pubchem（cid） Pubchem (cid): | 13387 |
| pubchem（sid） Pubchem (sid): | 134980916 |
| | 1-甲基吡咯烷-2-酮 1-methylpyrrolidin-2-one |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 51013-18-4 |
| pubchem（cid） Pubchem (cid): | 13387 |
| pubchem（sid） Pubchem (sid): | 135117211 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | M-pyrol | | N- | methyl pyrrolidone | | N- | methyl-2-ketopyrrolidine | | N- | methyl-2-pyrolidinone | | N- | methyl-2-pyrrolidinone | | 1- | 甲基-2-吡咯烷酮 methyl-2-pyrrolidone | | N- | 甲基-2-吡咯烷酮 methyl-2-pyrrolidone | | N- | methyl-a-pyrrolidinone | | N- | methyl-a-pyrrolidone | | 1- | methyl-pyrrolidin-2-one | | N- | methyl-pyrrolidone | | N- | methylbutyrolactam | | 1- | methylpyrrolidin-2-one | | N- | methylpyrrolidin-2-one | | | methylpyrrolidinone | | N- | methylpyrrolidinone | | N- | methylpyrrolidione | | N- | methylpyrrolidone | | | methylpyrrolidone, N- | | | pyrrolidin-2-one, 1-methyl- | | 2- | pyrrolidinone, 1-methyl- | | | pyrrolidinone, methyl- | | 2- | pyrrolidinone, methyl- | | 2- | pyrrolidone, 1-methyl |
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| 已发布 PubMed:从低温煤焦油中分离出的馏分的热解-气相色谱/质谱 Pyrolysis-gas chromatography/mass spectrometry of fractions separated from a low-temperature coal tar: 试图开发一种用于表征重烃液体的结构和组成的通用方法。 an attempt to develop a general method for characterising structures and compositions of heavy hydrocarbon liquids. |
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| 已发布 PubMed:液相色谱-质谱和液相色谱-串联质谱法测定河流生物膜中的n-甲基吡咯烷酮 Liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry determination of N-methylpyrrolidinone in riverine biofilms. |
| 已发布 PubMed:几种质谱方法对波罗的海琥珀及其溶剂提取物的结构表征。 Structural characterisation of Baltic amber and its solvent extracts by several mass spectrometric methods. |
| 已发布 PubMed:消炎双核和单核吲哚美辛锌复合物的合成和表征。 [zn2（吲哚美辛）4（l）2]的晶体结构（l = n Syntheses and characterization of anti-inflammatory dinuclear and mononuclear zinc indomethacin complexes. Crystal structures of [Zn2(indomethacin)4(L)2] (L = N,正二甲基乙酰胺 N-dimethylacetamide, pyridine, 1-甲基-2-吡咯烷酮）和[zn（吲哚美辛）2（l1）2]（l1 =乙醇 1-methyl-2-pyrrolidinone) and [Zn(indomethacin)2(L1)2] (L1 = ethanol, 甲醇）。 methanol). |
| 已发布 PubMed:尿可替宁的hptlc筛选测定作为男性青少年环境烟草烟雾暴露的生物标志物。 HPTLC screening assay for urinary cotinine as biomarker of environmental tobacco smoke exposure among male adolescents. |
| 已发布 PubMed:电感耦合等离子体质谱法鉴定木材和煤炭中有机缔合的微量元素 Identification of organically associated trace elements in wood and coal by inductively coupled plasma mass spectrometry. |
| 已发布 PubMed:与药物输送相关的plga解决方案的相转化动力学。第二部分溶液热力学和浴侧传质的作用。 Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath-side mass transfer. |
| 已发布 PubMed:小鼠emt-6肿瘤模型中氟化锌酞菁衍生物的光动力学活性和生物分布。 Photodynamic activities and biodistribution of fluorinated zinc phthalocyanine derivatives in the murine EMT-6 tumour model. |
| 已发布 PubMed:合成 synthesis, Structure, 和吡啶可溶碱土和硫醇钇的硫解反应。 and Thiolysis Reactions of Pyridine Soluble Alkaline Earth and Yttrium Thiolates. |
| 已发布 PubMed:尿中5-羟基-n-甲基吡咯烷酮和2-羟基-n-甲基琥珀酰亚胺的含量测定 Determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in human urine. |
| 已发布 PubMed:1-甲基-2-吡咯烷酮（nmp）在体内不会诱导结构和数值上的染色体畸变。 1-Methyl-2-pyrrolidinone (NMP) does not induce structural and numerical chromosomal aberrations in vivo. |
| 已发布 PubMed:3-氨基-1-（间三氟甲基苯基）-6-甲基-1h-哒嗪-4-酮的多晶型物和溶剂化物的表征。 Characterization of polymorphs and solvates of 3-amino-1-(m-trifluoromethylphenyl)-6-methyl-1H-pyridazin-4-one. |
| 已发布 PubMed:n-甲基吡咯烷酮作为偶联溶剂，并从树脂上裂解三氟甲烷磺酸，合成胰岛素样生长因子i。 Synthesis of insulin-like growth factor I using N-methyl pyrrolidinone as the coupling solvent and trifluoromethane sulphonic acid cleavage from the resin. |
| 已发布 PubMed:使用渗透促进剂透皮吸收 防护剂。 Transdermal absorption of radioprotectors using permeation-enhancing vehicles. |
| 已发布 PubMed:有机溶剂（包括橙花毒素）的混合物诱导染色体丢失。 Induction of chromosome loss by mixtures of organic solvents including neurotoxins. |
| 已发布 PubMed:在体外影响猪脑微管蛋白聚集的非质子传递极性溶剂可诱导低温生长的酵母细胞产生非整倍性。 Aprotic polar solvents that affect porcine brain tubulin aggregation in vitro induce aneuploidy in yeast cells growing at low temperatures. |
| 已发布 PubMed:酿酒酵母中非整倍性诱导化学组合的研究。 Investigations of aneuploidy-inducing chemical combinations in Saccharomyces cerevisiae. |
| 已发布 PubMed:两种酵母化合物在酿酒酵母中的非整倍性诱导 Aneuploidy induction in Saccharomyces cerevisiae by two solvent compounds, 1-甲基-2-吡咯烷酮和2-吡咯烷酮。 1-methyl-2-pyrrolidinone and 2-pyrrolidinone. |
| 已发布 PubMed:水杨酸酯和其他趋化性驱除剂在大肠杆菌k-12中对氯霉素和其他抗生素的非遗传抗性。 Nonheritable resistance to chloramphenicol and other antibiotics induced by salicylates and other chemotactic repellents in Escherichia coli K-12. |
| 已发布 PubMed:氯噻酮在甲醇中的降解 Degradation of chlorthalidone in methanol: 动力学和稳定性。 kinetics and stabilization. |
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3D/INCHI
3D/INCHI