(±)-扁桃酸 (±)-mandelic acid
苯乙酸 benzeneacetic acid, 羟基 a-hydroxy-

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    加热扁桃酸苦杏仁苷时首次发现扁桃酸 Mandelic acid was first discovered while heating amygdalin isolated from bitte
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    m0038 dl-扁桃酸> 99.0%(gc)(t) M0038 DL-Mandelic Acid >99.0%(GC)(T)
Name:2-羟基-2-苯基乙酸 2-hydroxy-2-phenylacetic acid
CAS号 CAS Number: 90-64-2Picture of molecule3D/INCHI
其他 Other:15769-78-5
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:202-007-6
FDA UNII:NH496X0UJX
nikkaji网站 Nikkaji Web:J3.918G
贝尔斯坦数 Beilstein Number:510011
MDL :mfcd00064250 MFCD00064250
XlogP3:0.60(est) 0.60 (est)
分子量 Molecular Weight:152.14936000
式 Formula:c8 h8 o3 C8 H8 O3
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:antimicrobial agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 119.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 321.83 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 325.00 °F. tcc TCC ( 162.60 °C. ) (est)
logp(o / w) logP (o/w): 0.620
溶于 Soluble in:
 水 water, 1.81E+05 mg/L @ 25 &deg °C (经验值 exp)
 水 water, 1.763e + 005 mg / l @ 25°c(est) 1.763e+005 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: antimicrobial agents
 
供应商 Suppliers:
American International Chemical, LLC.
扁桃酸 MANDELIC ACID NF
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
dl-扁桃酸 DL-Mandelic acid
气味 Odor: characteristic
采用 Use: 加热扁桃酸苦杏仁苷时首次发现扁桃酸 Mandelic acid was first discovered while heating amygdalin isolated from bitte
Jiangyin Healthway
扁桃酸 MANDELIC ACID NF
新功能食品成分 New functional food ingredients
Jiangyin Healthway
扁桃酸 MANDELIC ACID NF
生物技术公司 M.C.Biotec
扁桃酸 MANDELIC ACID NF
气味 Odor: characteristic
采用 Use: 用于抑制色素沉着 useful in suppressing pigmentation, 治疗炎性非囊性 treating inflammatory noncystic acne, 使光老化的皮肤恢复活力。此外,它已被证明对准备激光脱皮的皮肤以及在激光手术后帮助皮肤愈合方面是有用的。 and rejuvenating photoaged skin. Moreover it has proven useful in preparing the skin for laser peeling and in helping the skin heal after laser surgery.
Penta International
扁桃酸 MANDELIC ACID NF
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
dl-扁桃酸 DL-Mandelic acid
西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich
仅供实验/研究使用。 For experimental / research use only.
扁桃酸99% Mandelic acid 99%
化工行业 Spec-Chem Industry
规格白 SpecWhite &reg ® dl-ma DL-MA
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
dl-扁桃酸> 99.0%(gc)(t) DL-Mandelic Acid >99.0%(GC)(T)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
口服兔子 oral-rabbit ldlo LDLo 2000 mg/kg
胃肠道 GASTROINTESTINAL: 胃炎 GASTRITIS 肝 LIVER: 其他变化 OTHER CHANGES 胃肠道 GASTROINTESTINAL: 溃疡 ULCERATION OR 流血的 BLEEDING 从 FROM STOMACH
Archives 国际化 Internationales de 药代动力学 Pharmacodynamie et de 疗法 Therapie. 卷 Vol. 64, pg。 79 Pg. 79, 1940.

肌内大鼠 intramuscular-rat LD50 > 300 mg/kg
Experimental 药物 Medicine and 手术 Surgery. 卷 Vol. 4, pg。 223 Pg. 223, 1946.

腹膜内大鼠 intraperitoneal-rat LD50 4100 mg/kg
Bollettino 奇米科 Chimico 农艺 Farmaceutico. 卷 Vol. 112, pg。 53 Pg. 53, 1973.

口鼠 oral-rat ldlo LDLo 3000 mg/kg
Archives 国际化 Internationales de 药代动力学 Pharmacodynamie et de 疗法 Therapie. 卷 Vol. 64, pg。 79 Pg. 79, 1940.

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
antimicrobial agents
推荐使用(±)-扁桃酸使用水平 Recommendation for (±)-mandelic acid usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐使用(±)-扁桃酸风味剂的使用水平 Recommendation for (±)-mandelic acid flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
EPA物质注册服务(tsca TSCA) :90-64-2
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(srs Srs RS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :1292
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
2-羟基-2-苯基乙酸 2-hydroxy-2-phenylacetic acid
chemidplus Chemidplus:0000090642
技术 RTECS:CAS#90-64-2的oo6300000 OO6300000 for cas# 90-64-2
 
参考资料 References:
 2-羟基-2-苯基乙酸 2-hydroxy-2-phenylacetic acid
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:90-64-2
pubchem(cid) Pubchem (cid):1292
pubchem(sid) Pubchem (sid):134971115
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
KEGG (GenomeNet):C01984
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB00703
食物 FooDB:FDB022191
出口关税代码 Export Tariff Code:2918.19.1200
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 almond acid
 杏仁核 amygdalic acid
 苦杏仁苷 苦杏仁苷 amygdalinic acid
 苯乙酸 benzeneacetic acid, 羟基 a-hydroxy-
 gly大肠杆菌 colic acid, phenyl-
2-HPAA
(2rs RS)-2-hydroxy-2-phenylacetic acid
2-hydroxy-2-phenylacetic acid
DL-2-hydroxy-2-phenylacetic acid
(±)-2-hydroxy-2-phenylethanoic acid
2-hydroxy-2-phenylethanoic acid
a-hydroxy-a-toluic acid
 羟基苯乙酸 hydroxy-phenyl-acetic acid
 hydroxy(phenyl)acetic acid
DL-hydroxy(phenyl)acetic acid
(±)-a-hydroxy苯乙酸 benzeneacetic acid
a-hydroxy苯乙酸 benzeneacetic acid
(±)-a-hydroxyphenylacetic acid
a-hydroxyphenylacetic acid
 mandelic acid
(rs RS)-mandelic acid
DL-mandelic acid
racemic mandelic acid
DL-mandelicacid
 拟 paramandelic acid
2-phenyl-2-hydroxyacetic acid
 苯乙醇 phenylgly大肠杆菌 colic acid
2-苯乙醇 phenylgly大肠杆菌 colic acid
DL-苯乙醇 phenylgly大肠杆菌 colic acid
 苯羟基乙酸 phenylhydroxyacetic acid
a-toluic acid, 羟基 a-hydroxy-
 尿嘧啶 uromaline
 

文章 Articles:

已发布 PubMed:高粱醋中的糖醇和单糖可通过抑制环氧合酶1和血栓烷a2合酶来减弱血小板聚集。 Alditols and monosaccharides from sorghum vinegar can attenuate platelet aggregation by inhibiting cyclooxygenase-1 and thromboxane-A2 synthase.
已发布 PubMed:基因位点饱和诱变改善产碱菌粪便腈水解酶的方法及其在(r)-(-)-扁桃酸立体定向生物合成中的应用。 Improvement of Alcaligenes faecalis nitrilase by gene site saturation mutagenesis and its application in stereospecific biosynthesis of (R)-(-)-mandelic acid.
已发布 PubMed:得出基于健康的安全暴露极限,以防止潜在的消费者暴露于从食品容器中迁移到食品中的苯乙烯。 Derivation of safe health-based exposure limits for potential consumer exposure to styrene migrating into food from food containers.
已发布 PubMed:重组大肠杆菌对扁桃酸衍生物的氧化脱羧 Oxidative decarboxylation of mandelic acid derivative by recombinant Escherichia coli: 乙基香兰素合成的新方法。 a novel method of ethyl vanillin synthesis.
已发布 PubMed:基因克隆 Gene cloning, 表达 expression, 粪产碱菌zjutb10的腈水解酶的合成和表征。 and characterization of a nitrilase from Alcaligenes faecalis ZJUTB10.
已发布 PubMed:吸入联合使用乙苯和甲基乙基酮对大鼠的发育毒性。 Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats.
已发布 PubMed:气相色谱法测定尿中的扁桃酸对映体之前,先在超临界二氧化碳中衍生化。 Determination of mandelic acid enantiomers in urine by derivatization in supercritical carbon dioxide prior to their determination by gas chromatography.
已发布 PubMed:[具有防腐作用的新扁桃酸衍生物的合成。合成与急性毒性研究]。 [Synthesis of new mandelic acid derivatives with preservative action. Synthesis and acute toxicity study].
已发布 PubMed:使用固定化腈水解酶水解腈 Hydrolysis of nitriles using an immobilized nitrilase: 应用于蛋氨酸羟基类似物衍生物的合成。 applications to the synthesis of methionine hydroxy analogue derivatives.
已发布 PubMed:用于生产的酶生物反应器的构建来自苯甲酰基甲酸酯的(r)-扁桃酸酯。 Construction of an electro-enzymatic bioreactor for the production of (R)-mandelate from benzoylformate.
已发布 PubMed:慢性蛋白限制对苦参大鼠运动协调和脑橙花递质的影响。 Effect of chronic protein restriction on motor co-ordination and brain neurotransmitters in albino rats.
已发布 PubMed:亚氯酸术前皮肤消毒的临床疗效。 Clinical efficacy of a chlorous acid preoperative skin antiseptic.
已发布 PubMed:植物乳杆菌中氨基转移酶引发的苯丙氨酸向苯甲醛的转化 Conversion of phenylalanine to benzaldehyde initiated by an aminotransferase in lactobacillus plantarum
已发布 PubMed:肉鸡皮肤颜色受有机酸影响 Broiler skin color as affected by organic acids: 浓度和使用方法的影响。 influence of concentration and method of application.
已发布 PubMed:气相色谱同时测定扁桃酸和苯乙醛酸改进方法。 An improved method for the simultaneous determination of mandelic and phenylglyoxylic acids by gas chromatography.
已发布 PubMed:食物对市售胶囊中环戊酸酯的生物利用度的影响。 Effect of food on the bioavailability of cyclandelate from commercial capsules.
已发布 PubMed:比格犬胶囊中环己酸酯的生物利用度和溶出度 Bioavailability of cyclandelate from capsules in beagle dogs and dissolution rate: 与 类生物利用度的相关性。 correlations with bioavailability in humans.
 
笔记 Notes:
天然己酸(天然)己酸脱铁己酸脱己酸天然己酸天然己酸合成己酸合成FCC己酸己酸1-己酸萘酸己酸己酸(己酸)n己酸(己酸)天然己酸(天然) )己酸99% It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by monoamine oxidase and catechol-o-methyl transferase. It is also present in certain skin care products, 是其他生化产品生产中的中间分子 is an intermediate molecule in the production of other biochemicals, 可以用作分析试剂,并且是染料生产中的前体。 may be used as an analytical reagent and is a precursor in the manufacture of dyes. 甲萘醌通常不用作营养补充剂。据报道,大剂量甲萘醌会引起不良后果,包括由于g6pd缺乏引起的溶血性 Mandelic acid is an aromatic alpha hydroxy acid with the molecular formula C8H8O3. It is a white crystalline solid that is soluble in water and most common organic solvents. [HMDB]
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