乳酸焦谷氨酸 laevo-pyroglutamic acid
2-l-吡咯烷酮-5-羧酸 2-L-pyrrolidone-5-carboxylic acid

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Name: （2s）-5-氧吡咯烷-2-羧酸 (2S)-5-oxopyrrolidine-2-carboxylic acid CAS号 CAS Number: 98-79-3 3D/INCHI echa ECHA einecs EINECS - REACH 预注册 Pre-Reg: 202-700-3 FDA UNII: SZB83O1W42 nikkaji网站 Nikkaji Web: J4.959J 贝尔斯坦数 Beilstein Number: 0082132 MDL : mfcd00005272 MFCD00005272 XlogP3-AA: -0.80（est） -0.80 (est) 分子量 Molecular Weight: 129.11539000 式 Formula: c5 h7 n o3 C5 H7 N O3 生物活性总结 BioActivity Summary: 清单 listing 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:special dietary and nutritional additives   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 调香师和调味师 Perfumer and Flavorist: 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search 已发布 PubMed: 搜索 Search NCBI: 搜索 Search   物理性质 Physical Properties: 出现 Appearance: 白结晶性粉末（est） white crystalline powder (est) 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 熔点 Melting Point: 184.00 to 185.00 °C. @ 760.00 mm 汞 Hg 沸点 Boiling Point: 453.13 °C. @ 760.00 mm 汞 Hg (est) 闪点 Flash Point: 440.00 °F. tcc TCC ( 226.67 °C. ) logp（o / w） logP (o/w): -1.348（est） -1.348 (est) 溶于 Soluble in:   水 water, 476000毫克/升@ 13c（经验值 exp）   感官特性 Organoleptic Properties: 气味描述 Odor Description:温和的甜味空灵 mild sweet ethereal 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: CosIng: 化妆品数据 cosmetic data 化妆品用途 Cosmetic Uses: 湿润剂 humectants 保湿剂 moisturising agents   供应商 Suppliers: 乙酰苯 Aceto 焦谷氨酸 L-Pyroglutamic Acid 安徽海北 Anhui Haibei 乳酸焦谷氨酸 laevo-pyroglutamic acid BOC Sciences 仅供实验/研究使用。 For experimental / research use only. l-焦谷氨酸hplc> 95％ L-Pyroglutamic acid HPLC>95% Emd 微孔 Millipore 仅供实验/研究使用。 For experimental / research use only. （s）-（-）-2-吡咯烷酮-5-羧酸 (S)-(-)-2-Pyrrolidone-5-carboxylic acid sds Glentham Life Sciences 焦谷氨酸 L-Pyroglutamic Acid sds Minasolve Minasolve 焦谷氨酸衍生品 L-pyroGlutamic Acid & Derivatives Penta International 焦谷氨酸 L-Pyroglutamic Acid 圣克鲁斯生物技术 Santa Cruz Biotechnology 仅供实验/研究使用。 For experimental / research use only. 焦谷氨酸≥99％ L-pyroGlutamic Acid ≥99% sds 西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich 仅供实验/研究使用。 For experimental / research use only. 焦谷氨酸≥99.0％（t） L-pyroGlutamic Acid ≥99.0% (T) sds 苦瓜 Solabia 左旋油酸 L-Pidolic Acid 气味 Odor: characteristic 采用 Use: APC APC还是必须通过 体携带的众多分子的出色载体 , 这就是为什么它被用作合成中间体。所以 this is why it is used as a synthesis intermediate. Consequently, solabia pharma提供了高生物利用度的无机盐，例如磷酸镁。 SOLABIA Pharma offers highly bioavailable mineral salts such as Magnesium Pidolate. United International 焦谷氨酸 L-Pyroglutamic Acid   安全信息 Safety Information: 首选SDS Preferred SDS: 视图 View 欧洲信息 European information : 最重要的危害 Most important hazard(s): xi-刺激性 Xi - Irritant R 36/38 - 烦 的 Irritating to skin 皮 and 眼睛 eyes. S 02 - 保持 Keep out of the 达到 reach of 孩子们 children. S 24/25 - 避免 Avoid contact with skin 皮 and 眼睛 eyes. S 26 - In 案件 case of contact with 眼睛 eyes, 冲洗 rinse 立即 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical 忠告 advice. S 36 - 穿 Wear 适当 suitable 保护性 protective 服装 clothing.   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 口鼠 oral-rat LD50 > 1000 mg/kg United 状态 States 专利 Patent 文献 Document. 卷 Vol. #4882359 皮肤毒性 Dermal Toxicity: 皮下大鼠 subcutaneous-rat LD50 > 2000 mg/kg United 状态 States 专利 Patent 文献 Document. 卷 Vol. #4882359 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: special dietary and nutritional additives 推荐使用Laevo-焦谷氨酸使用水平 Recommendation for laevo-pyroglutamic acid usage levels up to:   不用于香水。 not for fragrance use.   推荐使用Laevo-焦谷氨酸风味剂的使用水平 Recommendation for laevo-pyroglutamic acid flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: 欧洲食品安全局（efsa EFSA）参考 : 食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 flavourings, 与钙有关的与食品（afc）接触的加工助剂和材料 processing aids and materials in contact with food (AFC) related to Calcium, 铁 iron, magnesium, 羟吡啶甲酸钾和锌为钙的来源 potassium and zinc L-pidolate as sources for calcium, 铁 iron, magnesium, 钾盐 potassium and 锌 zinc added added for nutritional 目的 purposes to food 补品 supplements and to 食物 foods 意向的 intended for 特定 particular nutritional uses 视图 View page or 视图 View pdf Epi系统 EPI System: 视图 View 癌症引文 Cancer Citations:搜索 Search 毒理学引文 Toxicology Citations:搜索 Search 橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search EPA物质注册服务（tsca TSCA） :98-79-3 EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（SRS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :7405 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data 德国wgk WGK Germany:3 （2s）-5-氧吡咯烷-2-羧酸 (2S)-5-oxopyrrolidine-2-carboxylic acid chemidplus Chemidplus:0000098793 技术 RTECS:tw3710000 for CAS＃98-79-3 TW3710000 for cas# 98-79-3   参考资料 References:   （2s）-5-氧吡咯烷-2-羧酸 (2S)-5-oxopyrrolidine-2-carboxylic acid NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI 加拿大国内分公司。清单 Canada Domestic Sub. List: 98-79-3 pubchem（cid） Pubchem (cid): 7405 pubchem（sid） Pubchem (sid): 134971460   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View 格尔姆代谢组数据库 Golm Metabolome Database: 搜索 Search KEGG (GenomeNet): C01879 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): HMDB00267 食物 FooDB: FDB014506 ymdb（酵母代谢组数据库） YMDB (Yeast Metabolome Database): YMDB00107 出口关税代码 Export Tariff Code: 2933.79.5000 fda食品添加剂状况清单 FDA Listing of Food Additive Status: 视图 View vcf在线 VCF-Online: 食品中的挥发性有机化合物 VCF Volatile Compounds in Food 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and core components note 没找到 None Found   潜在用途 Potential Uses:   湿润剂 humectants   保湿剂 moisturising agents   存在（自然 Occurrence (nature, food, 其他） other):note   molasses 搜索 Search pmc PMC Picture   大豆种子 soybean seed 搜索 Search Trop Picture   同义词 Synonyms: (S)-(-)-g- but butyro内酰胺 lactam-g-carboxylate (S)-(-)-g- but butyro内酰胺 lactam-g-carboxylic Acid L-pyro glutamic acid L- glutamic acid g-内酰胺 lactam L- glutamic acid 内酰胺 gamma-内酰胺 lactam laevo- glutamic acid 内酰胺 gamma-内酰胺 lactam   聚氯乙烯 PCA   蝶形的 pidolic acid 5-L-oxo proline 5-oxo-L- proline L- proline, 5-oxo- (-)- pyroglutamic acid (S)- pyroglutamic acid (2S)-5-oxo pyrrolidine-2-carboxylic acid (S)-5-oxo pyrrolidine-2-carboxylic acid (5S)-2-oxo pyrrolidine-5-carboxylate (2S)-5-oxo pyrrolidine-5-carboxylic acid (5S)-2-oxo pyrrolidine-5-carboxylic acid 2-oxo pyrrolidine-5(S)-carboxylate 2-oxo pyrrolidine-5(S)-carboxylic acid (S)-5-oxo-2- pyrrolidinecarboxylate L-5-oxo-2- pyrrolidinecarboxylate (S)-5-oxo-2- pyrrolidinecarboxylic acid (S)-(-)-2- pyrrolidinone-5-carboxylic Acid L- pyrrolidinonecarboxylate (S)-(-)-2- pyrrolidone-5-carboxylate L-2- pyrrolidone-5-carboxylate (S)-(-)-2- pyrrolidone-5-carboxylic acid (S)-2- pyrrolidone-5-carboxylic acid 2-L- pyrrolidone-5-carboxylic acid 2-laevo- pyrrolidone-5-carboxylic acid L- pyrrolidonecarboxylate   文章 Articles: 已发布 PubMed:使用气相色谱-质谱法基于亲水性成分分布图监测切达干酪的成熟过程。 Monitoring the ripening process of Cheddar cheese based on hydrophilic component profiling using gas chromatography-mass spectrometry. 已发布 PubMed: 用5-氧代脯氨酸酶同时测定酱油中L-谷氨酸和L-焦谷氨酸含量（无atp ATP水解活性）。 已发布 PubMed:生和熟食品中谷胱甘肽的风味特征。 Flavor characteristics of glutathione in raw and cooked foodstuffs. 已发布 PubMed:米曲霉介导的大豆异黄酮生物转化的靶向代谢组学 Targeted metabolomics for Aspergillus oryzae-mediated biotransformation of soybean isoflavones, 显示主要代谢产物的变化。 showing variations in primary metabolites. 已发布 PubMed:水传感器ppk28通过akh信号调节果蝇的寿命和生理。 Water sensor ppk28 modulates Drosophila lifespan and physiology through AKH signaling. 已发布 PubMed:绿橄榄和腌制黄瓜中味精的稳定性随包装条件和储存时间的变化而变化。 Stability of monosodium glutamate in green table olives and pickled cucumbers as a function of packing conditions and storage time. 已发布 PubMed:轻，重l-焦谷氨酸琥珀酰亚胺酯的同位素变体，作为通过液相色谱和电喷雾电离质谱法鉴定dl-氨基酸手性代谢组学的衍生试剂。 Isotopic variants of light and heavy L-pyroglutamic acid succinimidyl esters as the derivatization reagents for DL-amino acid chiral metabolomics identification by liquid chromatography and electrospray ionization mass spectrometry. 已发布 PubMed:脂肪代谢激素在刺激唾液腺活动中的作用 Role of adipokinetic hormone in stimulation of salivary gland activities: 萤火虫pyrrhocoris apterus apterus l。 （异翅目）作为模型物种。 已发布 PubMed:日本酒（清酒）中焦谷氨酰肽的鉴定 Identification of pyroglutamyl peptides in Japanese rice wine (sake): 肝保护性焦葡聚糖的存在。 presence of hepatoprotective pyroGlu-Leu. 已发布 PubMed:大西洋鳕鱼中的黑素浓缩激素（mch）和促性腺激素释放激素（gnrh） Melanin-concentrating hormone (MCH) and gonadotropin-releasing hormones (GnRH) in Atlantic cod, 加达斯·摩尔瓦 Gadus morhua: 组织分布 tissue distributions, 早期个体发育和禁食的影响。 early ontogeny and effects of fasting. 已发布 PubMed:使用气相色谱-质谱法基于亲水性成分分布图监测切达干酪的成熟过程。 Monitoring the ripening process of Cheddar cheese based on hydrophilic component profiling using gas chromatography-mass spectrometry. 已发布 PubMed:摄入低剂量的焦谷氨酰亮氨酸可改善硫酸葡聚糖钠诱导的小鼠结肠炎和肠道菌群。 Ingestion of low dose pyroglutamyl leucine improves dextran sulfate sodium-induced colitis and intestinal microbiota in mice. 已发布 PubMed:亚洲棕榈麝香猫咖啡（kopi luwak）鉴别标志的选择 Selection of discriminant markers for authentication of Asian palm civet coffee (Kopi Luwak): 代谢组学方法。 a metabolomics approach. 已发布 PubMed:对氨基二苯胺盐酸盐4-氨基二苯胺盐酸盐对氨基二苯胺盐酸盐4-氨基二苯胺盐酸盐-（4-氨基苯基）苯胺盐酸盐（4-氨基苯基）苯胺 Obesity-related metabolomic analysis of human subjects in black soybean peptide intervention study by ultraperformance liquid chromatography and quadrupole-time-of-flight mass spectrometry. 已发布 PubMed:匹多莫德对小鼠再发弓形虫病的预防作用。 Preventive effect of pidotimod on reactivated toxoplasmosis in mice. 已发布 PubMed:麸质水解物中抗d-半乳糖胺诱导的急性肝炎大鼠肝保护肽的鉴定 Identification of a hepatoprotective peptide in wheat gluten hydrolysate against D-galactosamine-induced acute hepatitis in rats. 已发布 PubMed:通过进食抑制条件气味的方法与果蝇的口味和营养价值无关。 Suppression of conditioned odor approach by feeding is independent of taste and nutritional value in Drosophila. 已发布 PubMed:酵母毕赤酵母分泌的甜味巴西青素的高效生产和表征。 Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast Pichia pastoris. 已发布 PubMed:蜜蜂中的卵黄蛋白原和少年激素共同影响味觉知觉和脂肪体能量代谢。 Gustatory perception and fat body energy metabolism are jointly affected by vitellogenin and juvenile hormone in honey bees. 已发布 PubMed:食物限制和脱水引起的多香果大鼠在前和尾pvn中表现出不同的trh表达。 2型脱碘酶和焦谷氨酰氨肽酶的作用ii。 Food-restricted and dehydrated-induced anorexic rats present differential TRH expression in anterior and caudal PVN. Role of type 2 deiodinase and pyroglutamyl aminopeptidase II. 已发布 PubMed:鞘翅类鳞茎的脂肪代谢激素（akhs） Adipokinetic hormones (AKHs) of sphingid Lepidoptera, 包括第二个m的标识。 Sexta akh。 including the identification of a second M. sexta AKH. 已发布 PubMed:流动注射三重串联四极杆串联质谱法测定植物油中的非蛋白质氨基酸和甜菜碱 Determination of nonprotein amino acids and betaines in vegetable oils by flow injection triple-quadrupole tandem mass spectrometry: 一种检测橄榄油掺假的筛选方法。 a screening method for the detection of adulterations of olive oils. 已发布 PubMed:脂肪动力学激素对拟南芥中肠特性的影响（异翅目）。 The effect of adipokinetic hormone on midgut characteristics in Pyrrhocoris apterus L. (Heteroptera). 已发布 PubMed:酱油中鲜味增强化合物的分离和鉴定。 Isolation and identification of the umami enhancing compounds in Japanese soy sauce. 已发布 PubMed:血管紧张素Ⅱ1型受体信号传导通过下丘脑中的厌食性促肾上腺皮质激素释放激素调节进食行为。 Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus. 已发布 PubMed:[大脑在调节新陈代谢和能量消耗中的作用 [Role of the brain in the regulation of metabolism and energy expenditure: 胰岛素的中心作用 the central role of insulin, 和脑的胰岛素抵抗]。 and insulin resistance of the brain]. 已发布 PubMed:代谢组学揭示了新型异黄酮和虫草发酵的最佳培养时间。 Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. 已发布 PubMed:合成2-亚氨基-3-亚甲基-5-羧基吡咯烷和2-亚氨基-3-亚甲基-6-羧基哌啶的氨基酸缀合物。 Synthesis of amino acid conjugates to 2-imino-3-methylene-5-carboxypyrrolidine and 2-imino-3-methylene-6-carboxypiperidine. 已发布 PubMed:代谢组学分析揭示了荫凉茶（山茶）的成分差异。 Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.). 已发布 PubMed:抗毒素肽的作用 Effect of anorexinergic peptides, 胆囊收缩素（cck）和 和苯丙胺调节的转录物（购物车）肽 cholecystokinin (CCK) and cocaine and amphetamine regulated transcript (CART) peptide, 对参与食物摄入调节的c57bl / 6小鼠下丘脑结构中橙花元活性的影响。 on the activity of neurons in hypothalamic structures of C57Bl/6 mice involved in the food intake regulation. 已发布 PubMed: 七鳗 Lamprey gnrh-iii在猪中释放促黄体激素，但不释放促卵泡激素。 已发布 PubMed:使用高压加工生产耐久的牧场敷料。 Production of shelf-stable ranch dressing using high-pressure processing. 已发布 PubMed:食品保护性乳酸杆菌-丙酸杆菌共培养产生的低分子量抗酵母代谢产物的特征。 Characterization of low-molecular-weight antiyeast metabolites produced by a food-protective Lactobacillus-Propionibacterium coculture. 已发布 PubMed:肥胖的胃电刺激 Gastric electrical stimulation for obesity: 需要使用更宽脉冲的新设备。 the need for a new device using wider pulses. 已发布 PubMed:葡萄糖稳态和食物摄入的可塑性自然变化。 Natural variation in plasticity of glucose homeostasis and food intake. 已发布 PubMed:的最后一个幼龄期中脂肪体存储的年龄依赖性变化以及脂肪代谢激素对脂肪体脂质合成和动员的调节 Age-dependent changes of fat body stores and the regulation of fat body lipid synthesis and mobilisation by adipokinetic hormone in the last larval instar of the cricket, gryllus 比目鱼 bimaculatus。 已发布 PubMed:四种相关半萜类的比较肽组学 Comparative peptidomics of four related hemipteran species: 焦蛋白 pyrokinins, 肌抑制素 myosuppressin, 考拉宁 corazonin, 脂肪代谢激素 adipokinetic hormone, snpf sNPF, 和粘膜素。 and periviscerokinins. 已发布 PubMed:水分活动对木贼抗药性和甜叶菊提取物对玉米种子中黄曲霉和细镰刀菌生长和霉菌毒素产生的影响 Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in female animals submitted to food-restriction or dehydration-induced anorexia and cold exposure. 已发布 PubMed:[ampk [AMPK, 积极控制新陈代谢的 ]。 an active player in the control of metabolism]. 已发布 PubMed:橙花性多香果的橙花橙花内分泌学。 Psychoneuroendocrinology of anorexia nervosa. 已发布 PubMed:酶促去除n末端焦谷氨酰基残基需要免疫球蛋白轻链和重链的解链。 Unfolding of the immunoglobulin light and heavy chains is required for the enzymatic removal of N-terminal pyroglutamyl residues. 已发布 PubMed:脂肪代谢激素诱导的动荡性肥胖性甘油三酸酯存储动员 Adipokinetic hormone-induced mobilization of fat body triglyceride stores in Manduca sexta: tg-脂肪酶和脂滴的作用。 role of TG-lipase and lipid droplets. 已发布 PubMed:大花紫苏花油紫苏花油紫苏花油紫苏花油frutescens花油紫苏花油丹参infuscata花油 Occurrence of the free and Peptide forms of pyroglutamic acid in plasma from the portal blood of rats that had ingested a wheat gluten hydrolysate containing pyroglutamyl peptides. 已发布 PubMed:脑干促甲状腺激素释放激素通过迷走素依赖性生长激素释放肽分泌的胆碱能刺激来调节食物摄入。 Brainstem thyrotropin-releasing hormone regulates food intake through vagal-dependent cholinergic stimulation of ghrelin secretion. 已发布 PubMed:大鼠下丘脑膜结合焦谷氨酰-2-萘酰胺水解活性的昼夜差异 Day-night differences in membrane-bound pyroglutamyl-2-naphthylamide-hydrolyzing activity in rat hypothalamus, 垂体 pituitary, 和视网膜。 and retina. 已发布 PubMed:机翼虫成虫雄性在代谢和内分泌控制中的机翼形态特异性差异 Wing morph-specific differences in the metabolism and endocrine control of reserve mobilization in adult males of a flightless bug, pyrrhocoris apterus apterus（l。）（heteroptera）。 已发布 PubMed:慢性乙醇或葡萄糖消耗会改变大鼠边缘区的trh含量和焦谷氨酰氨肽酶ii活性。 Chronic ethanol or glucose consumption alter TRH content and pyroglutamyl aminopeptidase II activity in rat limbic regions. 已发布 PubMed:产生akh的橙花内分泌细胞消融可降低海藻糖并诱导果蝇的行为变化。 AKH-producing neuroendocrine cell ablation decreases trehalose and induces behavioral changes in Drosophila. 已发布 PubMed:商业液体营养产品中的谷氨酰胺。 Glutamine in commercial liquid nutritional products. 已发布 PubMed:果蝇体内脂肪动力学激素编码基因的基因操作对血淋巴糖稳态和饥饿诱导的机能亢进的影响。 Hemolymph sugar homeostasis and starvation-induced hyperactivity affected by genetic manipulations of the adipokinetic hormone-encoding gene in Drosophila melanogaster. 已发布 PubMed:蟑螂中明串球菌抑制素的鉴定 Identification of leucomyosuppressin in the German cockroach, 德国小att Blattella germanica, 作为食物摄入的抑制剂。 as an inhibitor of food intake. 已发布 PubMed:前体的压力/温度联合处理会在n末端生成带有焦谷氨酸类激素肽。 Pressure/temperature combined treatments of precursors yield hormone-like peptides with pyroglutamate at the N terminus. 已发布 PubMed:美他多辛对大鼠的 毒性 [Reproductive toxicity of metadoxine in rats]. 已发布 PubMed:中央施用促甲状腺激素释放激素（trh）和相关肽可抑制西伯利亚仓鼠的进食行为。 Central administration of thyrotropin releasing hormone (TRH) and related peptides inhibits feeding behavior in the Siberian hamster. 已发布 PubMed:工业规模制备的小麦面筋酶解物中难消化的焦谷氨酰肽的分离和鉴定。 Isolation and identification of indigestible pyroglutamyl peptides in an enzymatic hydrolysate of wheat gluten prepared on an industrial scale. 已发布 PubMed:熟的微型奶酪中嗜热乳酸菌生产焦谷氨酸方法。 Production of pyroglutamic acid by thermophilic lactic acid bacteria in hard-cooked mini-cheeses. 已发布 PubMed:在感染及以后进行13c呼气测试。 13C breath tests in infections and beyond. 已发布 PubMed:刺骨相关蛋白（agrp）在下丘脑-垂体-甲状腺（hpt）轴上具有中枢抑制作用；比较agrp和橙花肽y对能量稳态和hpt轴的影响。 Agouti-related protein (AGRP) has a central inhibitory action on the hypothalamic-pituitary-thyroid (HPT) axis; comparisons between the effect of AGRP and neuropeptide Y on energy homeostasis and the HPT axis. 已发布 PubMed:非挥发性有机酸气相色谱/质谱分析法表征雪茄烟 Characterization of cigar tobaccos by gas chromatographic/mass spectrometric analysis of nonvolatile organic acids: 在古巴雪茄认证中的应用。 application to the authentication of Cuban cigars. 已发布 PubMed: 用5-氧代脯氨酸酶同时测定酱油中L-谷氨酸和L-焦谷氨酸含量（无atp ATP水解活性）。 已发布 PubMed:奶酪中的焦谷氨酸 Pyroglutamic acid in cheese: 存在 presence, 起源 origin, 与格兰达帕达诺奶酪的成熟时间相关。 and correlation with ripening time of Grana Padano cheese. 已发布 PubMed:在不含甘氨酸或无硫氨基酸饮食中，氧代脯氨酸动力学和氧代脯氨酸尿排泄。 Oxoproline kinetics and oxoproline urinary excretion during glycine- or sulfur amino acid-free diets in humans. 已发布 PubMed:肽中焦谷氨酸定量分析 Quantitative analysis of pyroglutamic acid in peptides 已发布 PubMed:肽中焦谷氨酸定量分析。 Quantitative analysis of pyroglutamic acid in peptides. 已发布 PubMed:健康年轻 中血浆L-5-氧代脯氨酸碳和氮动力学 Plasma L-5-oxoproline carbon and nitrogen kinetics in healthy young adults. 已发布 PubMed:饮食蛋白 Dietary protein, 营养不良的儿童和康复期间的生长和尿素动力学。 growth and urea kinetics in severely malnourished children and during recovery. 已发布 PubMed:隔离 Isolation, 家蝇利尿肌动蛋白橙花肽的表征和生物学活性 characterization and biological activity of a diuretic myokinin neuropeptide from the housefly, 家蝇。 Musca domestica. 已发布 PubMed:食物长期限制对肉种鸡雌性垂体对clhrh-i敏感性的影响。 Effect of long-term food restriction on pituitary sensitivity to cLHRH-I in broiler breeder females. 已发布 PubMed:对比的三种碎屑碳源对中营养 泊中浮游细菌代谢的影响。 Influence of Three Contrasting Detrital Carbon Sources on Planktonic Bacterial Metabolism in a Mesotrophic Lake. 已发布 PubMed:对2至24周龄摄食对雌性肉鸡种鸡的垂体和血浆中值突出和促性腺激素水平中lhrh-i含量的影响。 The effect of food intake from 2 to 24 weeks of age on LHRH-I content in the median eminence and gonadotrophin levels in pituitary and plasma in female broiler breeder chickens. 已发布 PubMed:生和熟食品中谷胱甘肽的风味特征。 Flavor characteristics of glutathione in raw and cooked foodstuffs. 已发布 PubMed:表征牛肉中粘稠的事后老化的化学属性。 Chemical attributes characterizing sticky post-mortem ageing in beef. 已发布 PubMed:trh样肽焦谷氨酰基-谷氨酰基-脯氨酸酰胺在大鼠中的尿排泄。 Urinary excretion of the TRH-like peptide pyroglutamyl-glutamyl-prolineamide in rats. 已发布 PubMed:进一步的证据表明速激肽pg-kii是nk-3中央的强效激动剂 Further evidence that the tachykinin PG-KII is a potent agonist at central NK-3, 但不是nk-1 but not NK-1, 受体。 receptors. 已发布 PubMed:从儿童严重营养不良中恢复期间，5-l-氧代脯氨酸（焦谷氨酸）的尿排泄增加，并对补充甘氨酸有反应。 Urinary excretion of 5-L-oxoproline (pyroglutamic acid) is increased during recovery from severe childhood malnutrition and responds to supplemental glycine. 已发布 PubMed:长期减少食物对雄性和雌性大鼠下丘脑-垂体-甲状腺轴的影响。 Effects of long-term food reduction on the hypothalamus-pituitary-thyroid axis in male and female rats. 已发布 PubMed:[加工过程中番茄化学成分的变化]。 [Changes in chemical composition of tomatoes during processing]. 已发布 PubMed:水发育的橙花元控制。 Neuronal control of development in hydra. 已发布 PubMed:食用种子的快速气相色谱筛选 Rapid gas chromatographic screening of edible seeds, 坚果和豆类用于非蛋白质和蛋白质氨基酸。 nuts and beans for non-protein and protein amino acids. 已发布 PubMed:饥饿诱导的促甲状腺激素释放激素（protrh）mrna的下丘脑含量变化和protrh衍生肽的下丘脑释放 Starvation-induced changes in the hypothalamic content of prothyrotrophin-releasing hormone (proTRH) mRNA and the hypothalamic release of proTRH-derived peptides: 肾上腺的作用。 role of the adrenal gland. 已发布 PubMed:毛细管气相色谱法测定蛋白质和生物氨基酸正（n）-叔丁基二甲基甲硅烷基衍生物 Capillary gas chromatographic determination of proteins and biological amino acids as N(O)-tert.-butyldimethylsilyl derivatives. 已发布 PubMed:食物对健康志愿者中匹多莫德生物利用度的影响。 Effect of food on the bioavailability of pidotimod in healthy volunteers. 已发布 PubMed:连续输注白介素-1和白介素-6对下丘脑-垂体-甲状腺轴的不同作用。 Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis. 已发布 PubMed:食物不足和甲状腺状态改变对大鼠下丘脑-垂体-甲状腺轴的影响 Effect of food deprivation and altered thyroid status on the hypothalamic-pituitary-thyroid axis in the rat. 已发布 PubMed:禁食期间抑制下丘脑促甲状腺激素释放激素信使核糖核酸。 Inhibition of hypothalamic thyrotropin-releasing hormone messenger ribonucleic acid during food deprivation. 已发布 PubMed:cck-8衍生物注入vmh引起的饱足感与特定的常量营养素选择有关。 Satiation due to CCK-8 derivative infusion into VMH is related to a specific macronutrient selection. 已发布 PubMed:静脉营养中半胱氨酸和l-2-氧代噻唑烷-4-羧酸作为半胱氨酸来源的有效性。 Availability of cysteine and of L-2-oxo-thiazolidine-4-carboxylic acid as a source of cysteine in intravenous nutrition. 已发布 PubMed:从膜中分离出一种抗食欲蛋白。 Isolation of an anorexigenic protein from membranes. 已发布 PubMed:酪蛋白在牛大肠杆菌中的分子克隆和表达 Molecular cloning and expression of bovine kappa-casein in Escherichia coli. 已发布 PubMed:从 粪便中分离出的一种物质抑制了大鼠的食物摄入。 Food intake suppression in rats by a substance isolated from human feces. 已发布 PubMed:促甲状腺激素释放激素（trh）集中发挥刺激大鼠胃收缩的作用。 Thyrotropin-releasing hormone (TRH) acts centrally to stimulate gastric contractility in rats. 已发布 PubMed:（pyro）glu-his-gly-oh类似物对大鼠食物消耗和胃酸分泌的影响 Effects of analogs of (pyro)Glu-His-Gly-OH on food consumption and gastric acid secretion in rats. 已发布 PubMed:icv脉冲注射或注入蛙皮素抑制饮水和进食 Drinking and feeding inhibition by ICV pulse injection or infusion of bombesin, 雷尼丁和利托林对大鼠。 ranatensin and litorin to rats. 已发布 PubMed:注射到大脑中的厌食肽的作用 Action of anorexigenic peptide injected into the brain: 解体对大鼠体重和摄食的影响。 dissociation of effect on body weight and feeding in the rat. 已发布 PubMed:缺乏pyro-glu-his-gly-oh肽对小鼠和大鼠食用的影响。 Lack of effect of the peptide pyro-Glu-His-Gly-OH on food consumption in mice and rats. 已发布 PubMed:没有证据表明pglu-his-gly在大鼠和小鼠中具有厌食特性。 No proof of anorectic properties of pGlu-His-Gly in rats and mice. 已发布 PubMed:全氟链烷酸在制备型hplc中作为挥发性离子配对试剂的用途。 Use of perfluoroalkanoic acids as volatile ion pairing reagents in preparative HPLC. 已发布 PubMed:合成的和拟议的食源性试剂活性测定 Synthesis and assay for activity of a proposed anorexogenic agent, 1-吡谷氨酰基-1-组氨酸-甘氨酸。 L-pyroglutamyl-L-histidyl-glycine. 已发布 PubMed:刺激犬胰多肽 Stimulation of canine pancreatic polypeptide, 胃泌素 gastrin, 肾上腺素对胃酸分泌的影响 and gastric acid secretion by ranatensin, 利托林 litorin, 蛙皮素九肽和物质p。 bombesin nonapeptide and substance P. 已发布 PubMed:报道的厌食三肽的实验 Experiments with a reported anorexigenic tripeptide: pyro-glu-his-gly-哦。 pyro-Glu-His-Gly-OH.

笔记 Notes: 1-谷氨酸环化衍生物。血液水平升高可能与谷氨酰胺或谷胱甘肽代谢问题有关。在蔬菜中发现 a cyclized derivative of l-glutamic acid. elevated blood levels may be associated with problems of glutamine or glutathione metabolism. Found in vegetables, 水果和糖蜜 fruits and molasses 1-谷氨酸环化衍生物。它是一种不常见的氨基酸衍生物，其中谷氨酸游离氨基环化形成内酰胺。 A cyclized derivative of L-glutamic acid. It is an uncommon amino acid derivative in which the free amino group of glutamic acid cyclizes to form a lactam.