acetaminophen
乙酰苯胺 acetanilide, 4'-羟基- -hydroxy-

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    01-02300对乙酰氨基酚usp 01-02300 ACETAMINOPHEN USP
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Name:正(4-羟苯基)乙酰胺 N-(4-hydroxyphenyl)acetamide
CAS号 CAS Number: 103-90-2Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:203-157-5
FDA UNII:362O9ITL9D
nikkaji网站 Nikkaji Web:J4.025H
贝尔斯坦数 Beilstein Number:2208089
MDL :mfcd00002328 MFCD00002328
XlogP3:0.50(est) 0.50 (est)
分子量 Molecular Weight:151.16513000
式 Formula:c8 h9 n o2 C8 H9 N O2
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:stabilising agents
 
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pubchem专利 Pubchem Patents:搜索 Search
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NCBI:搜索 Search
dg sante食品接触材料 DG SANTE Food Contact Materials:n-(4-羟苯基)乙酰苯胺 N-(4-hydroxyphenyl)acetanilide
 
物理性质 Physical Properties:
出现 Appearance:白固体(est) white solid (est)
化验 Assay: 98.00至100.00 98.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 169.00 to 171.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 387.00 to 389.00 °C. @ 760.00 mm 汞 Hg
闪点 Flash Point: 371.00 °F. tcc TCC ( 188.33 °C. )
logp(o / w) logP (o/w): 0.475(est) 0.475 (est)
溶于 Soluble in:
 alcohol
 水 water, 3.035e+004 mg/L @ 25 &deg °C (est)
 水 water, 1.40e + 04 mg / l @ 25°C(实验) 1.40E+04 mg/L @ 25 °C (exp)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: stabilising agents
 
供应商 Suppliers:
bbfy工业 BBFY Industrial
Paracetamol
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
氨二喹杂质b Amodiaquine Impurity B
气味 Odor: characteristic
采用 Use: 选择性cox-2抑制剂 A selective COX-2 inhibitor
碳合蛋白 Carbosynth
仅供实验/研究使用。 For experimental / research use only.
4-乙酰氨基酚 4-Acetamidophenol
食品化学国际 Foodchem International
Paracetamol
Glentham Life Sciences
4-乙酰氨基酚 4-Acetamidophenol
Novacyl Novacyl
罗丹帕 Rhodapap &reg ®
Penta International
对乙酰氨基酚颗粒usp ACETAMINOPHEN GRANULAR USP
Penta International
对乙酰氨基酚 Acetaminophen BioXtra
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
对乙酰氨基酚≥99% Acetaminophen ≥99%
西格玛·奥尔德里奇 Sigma-Aldrich
仅供实验/研究使用。 For experimental / research use only.
对乙酰氨基酚 Acetaminophen BioXtra, ≥99.0%
 
安全信息 Safety Information:
首选sds SDS : 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
几内亚口服 口服 oral-guinea 猪 pig LD50 2620 mg/kg kg
行为的 BEHAVIORAL: 嗜睡(一般抑郁活动) SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)Studi Sassaresi 行为的 BEHAVIORAL: 改变的睡眠时间(包括矫正反射改变) ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) 行为的 BEHAVIORAL: 震颤 TREMOR
日志 Journal of the 美国 American 制药业 Pharmaceutical 协会 Association, 科学版。卷47 Scientific Edition. Vol. 47, pg。 479 Pg. 479, 1958.

口头的 口服 oral- 的 human LD50 143 mg/kg kg
British 医疗 中 Medical 日志 Journal. 卷 Vol. 282, pg。 199 Pg. 199, 1981.

口头的 口服 oral- 的 human LD50 357 mg/kg kg
British 医疗 中 Medical 日志 Journal. 卷 Vol. 282, pg。 199 Pg. 199, 1981.

腹腔内小鼠 intraperitoneal-老鼠 mouse LD50 367 mg/kg kg
行为的 BEHAVIORAL: ANALGESIA
Arzneimittel-Forschung. 药品 Drug ug 研究 Research. 卷 Vol. 15, pg。 520 Pg. 520, 1965.

老鼠 口服 oral-老鼠 mouse LD50 338 mg/kg kg
Toxicology and 已应用 Applied 药理 Pharmacology. 卷 Vol. 19, pg。 20 Pg. 20, 1971.

腹膜内大鼠 intraperitoneal-rat LD50 1205 mg/kg kg
行为的 BEHAVIORAL: 震颤 TREMOR 行为的 BEHAVIORAL: 嗜睡(一般抑郁活动) SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)Studi Sassaresi
研究 Studi 萨萨雷西 Sassaresi, sezione 2。 57 Sezione 2. Vol. 57, pg。 561 Pg. 561, 1979.

口鼠 口服 oral-rat LD50 1944 mg/kg kg
联合的 United 状态 States 专利 Patent 文献 do Document. 卷 Vol. #4636513

口头儿 口服 oral-child ldlo LDLo 50 mg/kg kg
肾 KIDNEY, 输尿管 URETER, 和膀胱 AND BLADDER: "肾小管改变(包括急性肾衰竭) CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, 急性肾小管坏死 ACUTE TUBULAR NECROSIS)" 肺 LUNGS, 胸部 THORAX, 或呼吸 OR RESPIRATION: 急性肺水肿 ACUTE PULMONARY EDEMA 心脏的 CARDIAC: 其他变化 OTHER CHANGES
美国 American 日志 Journal of 紧急情况 Emergency 药物 中 Medicine. 卷 Vol. 6, pg。 510 Pg. 510, 1988.

口头儿 口服 oral-child ldlo LDLo 140 mg/kg kg/7D-I
BLOOD: "血清成分的变化(例如 CHANGES IN SERUM COMPOSITION (E.G., tp TP, 胆红素 BILIRUBIN, 胆固醇) CHOLESTEROL)" 行为的 BEHAVIORAL: 昏迷 COMA 肝 LIVER: "肝炎(肝细胞坏死) HEPATITIS (HEPATOCELLULAR NECROSIS), 带状 ZONAL"
医疗 中 Medical 日志 Journal of 澳大利亚 Australia. 卷 Vol. 171, pg。 472 Pg. 472, 1999.

口头儿 口服 oral-child ldlo LDLo 360 mg/kg kg/2D
肝 LIVER: 其他变化 OTHER CHANGES 皮肤和附属物(皮肤) SKIN AND APPENDAGES (SKIN): "皮炎 DERMATITIS, 其他 Other: 全身暴露后 AFTER SYSTEMIC EXPOSURE" 胃肠道 GASTROINTESTINAL: 恶心或呕吐 NAUSEA OR VOMITING
日志 Journal of 儿科 小儿科 Pediatrics. 卷 Vol. 92, pg。 832 Pg. 832, 1978.

口头儿 口服 oral-child tdlo TDLo 591 mg/kg kg/2D-I
BLOOD: 再生障碍性 APLASTIC ANEMIA 肝 LIVER: 肝功能检查受损 LIVER FUNCTION TESTS IMPAIRED 肾 KIDNEY, 输尿管 URETER, 和膀胱 AND BLADDER: "肾小管改变(包括急性肾衰竭) CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, 急性肾小管坏死 ACUTE TUBULAR NECROSIS)"
临床 Clinical 儿科 小儿科 Pediatrics 卷 Vol. 33, pg。 42 Pg. 42, 1994.

口头儿 口服 oral-child tdlo TDLo 801 mg/kg kg
肝 LIVER: 其他变化 OTHER CHANGES 胃肠道 GASTROINTESTINAL: 恶心或呕吐 NAUSEA OR VOMITING 行为的 BEHAVIORAL: 一般 GENERAL ANESTHETIC
儿科 小儿科 Pediatrics. 卷 Vol. 61, pg。 68 Pg. 68, 1978.

静脉狗 静脉 intra静脉的 venous-狗 dog ldlo LDLo 826 mg/kg kg
行为的 BEHAVIORAL: ANALGESIA
Archives 国际化 Internationales de 药代动力学 Pharmacodynamie et de 疗法 Therapie. 卷 Vol. 149, pg。 571 Pg. 571, 1964.

口头狗 口服 oral-狗 dog ldlo LDLo 2000 mg/kg kg
BLOOD: 脾脏变化 CHANGES IN SPLEEN 行为的 BEHAVIORAL: 改变的睡眠时间(包括矫正反射改变) ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
iyakuhin Iyakuhin 贤九 Kenkyu. 研究 Study of 医疗 中 Medical 耗材 补给 Supplies. 卷 Vol. 24, pg。 602 Pg. 602, 1993.

口头的 口服 oral- 的 human ldlo LDLo 143 mg/kg kg
行为的 BEHAVIORAL: 一般 GENERAL ANESTHETIC
British 医疗 中 Medical 日志 Journal. 卷 Vol. 282, pg。 199 Pg. 199, 1981.

口头的 口服 oral- 的 human ldlo LDLo 357 mg/kg kg
胃肠道 GASTROINTESTINAL: 恶心或呕吐 NAUSEA OR VOMITING 行为的 BEHAVIORAL: 多香果( ANOREXIA (HUMAN 行为的 BEHAVIORAL: 昏迷 COMA
Lancet. 卷 Vol. 1, pg。 66 Pg. 66, 1973.

哺乳动物 口服 oral-mammal (种类 species 未指定 unspecified) ldlo LDLo 512 mg/kg kg
联合的 United 状态 States 专利 Patent 文献 do Document. 卷 Vol. #4035499

口头 口服 oral-man ldlo LDLo 143 mg/kg kg/24H-
行为的 BEHAVIORAL: 多香果( ANOREXIA (HUMAN 肝 LIVER: "肝炎(肝细胞坏死) HEPATITIS (HEPATOCELLULAR NECROSIS), 带状 ZONAL" 肝 LIVER: "黄疸 JAUNDICE, 其他 Other OR UNCLASSIFIED"
美国 American 日志 Journal of 药物 中 Medicine. 卷 Vol. 74, pg。 349 Pg. 349, 1983.

口头 口服 oral-man ldlo LDLo 714 mg/kg kg
肝 LIVER: 其他变化 OTHER CHANGES
的 Human Toxicology. 卷 Vol. 1, pg。 25 Pg. 25, 1981.

口头 口服 oral-man tdlo TDLo 9286 ug ug/kg kg
感官和特殊感官 SENSE ORGANS AND SPECIAL SENSES: 其他 Other: 眼睛 EYE 皮肤和附属物(皮肤) SKIN AND APPENDAGES (SKIN): "皮炎 DERMATITIS, 其他 Other: 全身暴露后 AFTER SYSTEMIC EXPOSURE" 感官和特殊感官 SENSE ORGANS AND SPECIAL SENSES: 其他 Other: EAR
过敏 Allergy. 卷 Vol. 50(补给 Suppl

口头 口服 oral-man tdlo TDLo 714 mg/kg kg
心脏的 CARDIAC: ekg kg EKG 变化 更改 CHANGES not NOT 诊断 DIAGNOSTIC OF ABOVE
Postgraduate 医疗 中 Medical 日志 Journal. 卷 Vol. 69, pg。 52 Pg. 52, 1993.

皮肤毒性 Dermal Toxicity:
皮下老鼠 subcutaneous-老鼠 mouse LD50 310 mg/kg kg
的 Human Toxicology. 卷 Vol. 3, pg。 13秒 Pg. 13S, 1984.

皮下青蛙 subcutaneous-frog ldlo LDLo 50 mg/kg kg
行为的 BEHAVIORAL: 共济失调 ATAXIA 行为的 BEHAVIORAL: 改变的睡眠时间(包括矫正反射改变) ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) 肺 LUNGS, 胸部 THORAX, 或呼吸 OR RESPIRATION: 其他变化 OTHER CHANGES
Archiv 富尔 fuer 实验 Experimentelle 病理学 Pathologie und 药理学 Pharmakologie. 卷 Vol. 33, pg。 216 Pg. 216, 1894.

吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
stabilising agents
对乙酰氨基酚使用水平的推荐值 Recommendation for acetaminophen usage levels up to:
 不用于香水。 not for fragrance use.
 
对乙酰氨基酚风味使用水平的推荐值 Recommendation for acetaminophen flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
临床 Clinicaltrials.gov :search
每日医学 Daily Med:search
尼什国际化学品安全卡 NIOSH International Chemical Safety Cards:search
nlm NLM有害物质数据库 :搜索 Search
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
致癌力数据库 Carcinogenic Potency Database:搜索 Search
epa遗传毒理学 EPA GENetic TOXicology:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search
EPA物质注册服务(tsca TSCA) :103-90-2
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :1983
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
正(4-羟苯基)乙酰胺 N-(4-hydroxyphenyl)acetamide
chemidplus Chemidplus:0000103902
epa / noaa客串 EPA/NOAA CAMEO:有害物质 hazardous materials
技术 RTECS:103-90-2
 
参考资料 References:
 正(4-羟苯基)乙酰胺 N-(4-hydroxyphenyl)acetamide
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:103-90-2
pubchem(cid) Pubchem (cid):1983
pubchem(sid) Pubchem (sid):134972565
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
用于食品接触物质的fda间接添加剂 FDA Indirect Additives used in Food Contact Substances:视图 View
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
嗯bbd UM BBD:搜索 Search
KEGG (GenomeNet):C06804
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB01859
食物 FooDB:FDB022713
出口关税代码 Export Tariff Code:2924.29.4690
医药线 MedlinePlusSupp:视图 View
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
配方/制剂 Formulations/Preparations:
一般可用的药物 drug available generically: 胶囊500毫克;滴100毫克/毫升;长生不老药80 capsules 500 mg; drops 100 mgml; elixir 80, 120, 130, 160和325 mg5 ml;药片80(咀嚼)325 160 and 325 mg5 ml; tablets 80 (chewable) 325, 500, 和650毫克;栓剂120 and 650 mg; suppositories 120, 325, 和650毫克(所有形式均为非处方)。 and 650 mg (all forms nonprescription).
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
 analgesic agents
 抗菌剂 antimicrobial agents
 中枢橙花系统药物 central nervous system agents
 stabilising agents
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 阿贝醇 abenol
 阿贝沙尼 abensanil
 阿布罗尔 abrol
 acamol acamol
 直击 accu-tap
 acenol acenol
 对乙酰苯 acephen
 紫杉醇 acertol
 醋酸纤维 acetaco
 醋酸 acetagesic
 乙酰胺 acetamide, n- N-(4-hydroxyphenyl)-
 乙酰胺 acetamide, n- N-(对羟基苯 p-hydroxyphenyl)-
 acetamidophenol
4-acetamidophenol
 acetaminofen
4-acetaminophenol
p-acetaminophenol
 acetamol
 乙酰苯胺 acetanilide, 4'-羟基- -hydroxy-
 acetofen
n- N-acetyl-4-aminophenol
n- N-acetyl-对氨基p-aminophenol
4-(乙酰氨基 acetylamino)phenol
p-(乙酰氨基 acetylamino)phenol
p-乙酰氨基 acetylaminophenol
 APAP
n- N-(4-hydroxy-phenyl)-乙酰胺 acetamide
4'-hydroxy乙酰苯胺 acetanilide
p-hydroxy乙酰苯胺 acetanilide
n- N-(4-hydroxyphenyl)acetamid
n- N-(4-hydroxyphenyl)乙酰胺 acetamide
n- N-(p-hydroxyphenyl)乙酰胺 acetamide
n- N-(4-hydroxyphenyl)乙酰苯胺 acetanilide
 英奇 INCI acetaminophen
 扑热息痛 paracetamol
 phenol, 对乙酰氨基 p-acetamido-
 罗丹帕 rhodapap
 

文章 Articles:

已发布 PubMed:活性炭-酸奶混合物与活性炭-水浆液在体内和体外的吸附能力的比较。 Comparison of the adsorption capacities of an activated-charcoal--yogurt mixture versus activated-charcoal--water slurry in vivo and in vitro.
已发布 PubMed:烯丙基二烯丙基硫(das)及其相关化合物抑制化学毒性和致癌作用的机理。 Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic.
已发布 PubMed:大蒜和相关有机硫化合物对乙酰氨基酚引起的小鼠肝毒性的保护作用。 Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:与儿童和青少年不良事件相关的药物。 Drugs Associated with Adverse Events in Children and Adolescents.
已发布 PubMed:硫糖铝与克林霉素局部治疗对6至12岁儿童 切除术后疼痛的影响 Effect of Topical Sucralfate vs Clindamycin on Posttonsillectomy Pain in Children Aged 6 to 12 Years: 三盲随机临床试验。 A Triple-Blind Randomized Clinical Trial.
已发布 PubMed:患有乳腺炎的妇女食用益生菌菌株后的尿代谢组学指纹图谱。 Urinary metabolomic fingerprinting after consumption of a probiotic strain in women with mastitis.
已发布 PubMed:鸡肉和其他食用动物产品中的药品和个 护理产品 Pharmaceuticals and personal care products in chicken meat and other food animal products: 市场购物试验研究。 A market-basket pilot study.
已发布 PubMed:大型家庭医疗服务中患者对乙酰氨基酚的认知和知识。 Patient perception and knowledge of acetaminophen in a large family medicine service.
已发布 PubMed:三级护理中心住院 口中对乙酰氨基酚的使用量每天超过4克。 Patterns of acetaminophen use exceeding 4 grams daily in a hospitalized population at a tertiary care center.
已发布 PubMed:鉴定和定量防风湿病假越南草药中的成分。 Identification and quantitation of the ingredients in a counterfeit Vietnamese herbal medicine against rheumatic diseases.
已发布 PubMed: 液晶显示器 LC-ms MS / ms MS测定掺假食品和膳食补充剂中的非 类镇痛药。
已发布 PubMed:fda要求医生停止开出大剂量对乙酰氨基酚产品。 FDA asks physicians to stop prescribing high-dose acetaminophen products.
已发布 PubMed:紫甘薯花色苷对急性和慢性化学性肝损伤的口服肝保护能力评价 Oral hepatoprotective ability evaluation of purple sweet potato anthocyanins on acute and chronic chemical liver injuries.
已发布 PubMed:药物性肝损伤。 Drug-induced liver injury.
已发布 PubMed:红松林及其主要成分 Gymnaster koraiensis and its major components, 3,5-二-邻-咖啡酰基奎宁酸和体操剂 5-di-O-caffeoylquinic acid and gymnasterkoreayne B, 降低hepg2细胞中氢过氧化叔丁基或对乙酰氨基酚引起的氧化损伤。 reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells.
已发布 PubMed:Haiti's food and 喝 喝 drinking 水 water: 毒理学健康风险审查。 a review of toxicological health risks.
已发布 PubMed:小儿对乙酰氨基酚 Acetaminophen in children: 有新警告的旧药。 an old drug with new warnings.
已发布 PubMed:血浆和尿液中基于1h nmr的代谢组学对乙酰氨基酚引起的肝毒性的模式识别分析。 Pattern recognition analysis for hepatotoxicity induced by acetaminophen using plasma and urinary 1H NMR-based metabolomics in humans.
已发布 PubMed:氧化应激介导的器官病理生理学的最新进展。 An update on oxidative stress-mediated organ pathophysiology.
已发布 PubMed:代谢组学评估绿茶提取物对乙酰氨基酚诱导的小鼠肝毒性的作用。 Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:暴露对单性轮虫中乙酰胆碱酯酶(ache)活性和ache基因表达的影响 Effect of pharmaceuticals exposure on acetylcholinesterase (AchE) activity and on the expression of AchE gene in the monogonont rotifer, 臂章 Brachionus koreanus.
已发布 PubMed:酪蛋白钙与卵磷脂结合使用以掩盖对乙酰氨基酚的苦味-酪蛋白酸钠的对比研究 Use of calcium caseinate in association with lecithin for masking the bitterness of acetaminophen--comparative study with sodium caseinate.
已发布 PubMed:每日一次的glp-1类似物利拉鲁肽对胃排空的影响 Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, 血糖参数 glycemic parameters, 肥胖者的食欲和能量代谢 appetite and energy metabolism in obese, 非糖尿病成年 。 non-diabetic adults.
已发布 PubMed:自由贸易区 FDA: 对乙酰氨基酚可能会引发严重的皮肤问题。 Acetaminophen may trigger serious skin problems.
已发布 PubMed:在对乙酰氨基酚诱导的 大鼠中口服α-硫辛酸可减轻 。 Attenuation of uremia by orally feeding alpha-lipoic acid on acetaminophen induced uremic rats.
已发布 PubMed:在茶中添加牛奶会延迟胃排空吗? Does adding milk to tea delay gastric emptying?
已发布 PubMed:交联和干燥方法对酪蛋白-果胶微粒递药性能的影响 Impact of cross-linking and drying method on drug delivery performance of casein-pectin microparticles.
已发布 PubMed:保肝 Hepatoprotective, 抗氧化剂 antioxidant, 姜(姜)和维生素E对乙酰氨基酚治疗的大鼠的改善作用。 and ameliorative effects of ginger (Zingiber officinale Roscoe) and vitamin E in acetaminophen treated rats.
已发布 PubMed:具有预测能力的体外胃肠道模型(tim) In vitro gastrointestinal model (TIM) with predictive power, 即使是婴幼儿? even for infants and children?
已发布 PubMed:液相色谱-串联质谱法同时定量大鼠血浆中咖啡因及其三种主要代谢产物。 Simultaneous quantification of caffeine and its three primary metabolites in rat plasma by liquid chromatography-tandem mass spectrometry.
已发布 PubMed:谷胱甘肽在肝损伤中的防御机制 Glutathione defense mechanism in liver injury: 动物模型的见解。 insights from animal models.
已发布 PubMed:食物粘度对进食率的影响 The impact of food viscosity on eating rate, 主观食欲 subjective appetite, 血糖反应和胃排空率。 glycemic response and gastric emptying rate.
已发布 PubMed:核红细胞2相关因子2 Nuclear erythroid 2-related factor 2: 肝纤维化的新型潜在治疗靶标。 a novel potential therapeutic target for liver fibrosis.
已发布 PubMed:康普茶的保肝作用 Hepatoprotective effects of kombucha tea: 鉴定功能菌株和量化功能成分。 identification of functional strains and quantification of functional components.
已发布 PubMed:芹菜素对乙酰氨基酚引起的小鼠急性肝损伤的保护作用与肝谷胱甘肽还原酶活性的增加有关。 Protective effect of apigenin on mouse acute liver injury induced by acetaminophen is associated with increment of hepatic glutathione reductase activity.
已发布 PubMed: fas受体缺陷型lpr lpr小鼠由于较高的谷胱甘肽合成和增强的氧化应激解毒作用而被保护免受对乙酰氨基酚肝毒性。
已发布 PubMed: [通过液晶显示器 LC-ms MS / ms MS迅速鉴别出抗普通感冒药与捷运 MRM的15种有效成分]。
已发布 PubMed:davallialactone可以防止对乙酰氨基酚过量引起的小鼠肝损伤。 Davallialactone protects against acetaminophen overdose-induced liver injuries in mice.
已发布 PubMed:狗粮对活性炭吸附能力影响的体外研究。 In vitro study of the effect of dog food on the adsorptive capacity of activated charcoal.
已发布 PubMed:金合欢皮和空荚提取物对扑热息痛中毒的肝损伤和四氧嘧啶诱发的Ⅱ型糖尿病的保护作用。 Protective effect of bark and empty pod extracts from Acacia auriculiformis against paracetamol intoxicated liver injury and alloxan induced type II diabetes.
已发布 PubMed: 类药物治疗慢性疼痛 Opioids for chronic pain: 新证据 new evidence, 新策略 new strategies, 安全开药。 safe prescribing.
已发布 PubMed:fda小组建议使用更严格的 类药物处方规则。 FDA panel recommends tighter rules for prescribing opioids.
已发布 PubMed:延长释放的氢可酮-礼物还是诅咒? Extended-release hydrocodone - gift or curse?
已发布 PubMed:药物诱发的肝损伤模型,用于评估植物治疗药和其他天然产物。 Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products.
已发布 PubMed:金雀异黄素通过对udp-葡萄糖醛酸糖基转移酶和抗氧化酶的激活产生潜在的影响,从而防止乙酰氨基酚引起的肝损伤。 Genistein protection against acetaminophen-induced liver injury via its potential impact on the activation of UDP-glucuronosyltransferase and antioxidant enzymes.
已发布 PubMed:乳清蛋白水解物对扑热息痛诱导的氧化应激的改善潜力。 Ameliorative potential of whey protein hydrolysate against paracetamol-induced oxidative stress.
已发布 PubMed:定量的去氨贴地煎汤和D-松糖醇对大鼠化学性肝损伤的抗肝毒性作用。 Antihepatotoxic activity of a quantified Desmodium adscendens decoction and D-pinitol against chemically-induced liver damage in rats.
已发布 PubMed:直径为三十和五十纳米的二氧化硅纳米颗粒引起的肝损伤。 Liver injury induced by thirty- and fifty-nanometer-diameter silica nanoparticles.
已发布 PubMed:柚皮苷对金属硫蛋白(mt)无效小鼠对乙酰氨基酚诱导的急性肝损伤的保护作用。 Protective effect of naringenin against acetaminophen-induced acute liver injury in metallothionein (MT)-null mice.
已发布 PubMed:儿科对乙酰氨基酚临床药理学的法规审查。 Regulatory review of acetaminophen clinical pharmacology in young pediatric patients.
已发布 PubMed:非处方药与姜黄素的相互作用 Interaction of over-the-counter drugs with curcumin: 对肠道细胞稳定性和生物活性的影响。 influence on stability and bioactivities in intestinal cells.
已发布 PubMed:沉积物中药物存在的风险评估 Risk assessment on the presence of pharmaceuticals in sediments, pego-oliva Pego-Oliva沼泽地(瓦伦西亚)的土壤和水域 , 西班牙东部)。 eastern Spain).
已发布 PubMed:黄酮类化合物对谷胱甘肽S-转移酶的抑制和诱导 Inhibition and induction of glutathione S-transferases by flavonoids: 可能的药理毒理后果。 possible pharmacological and toxicological consequences.
已发布 PubMed:fda限制对乙酰氨基酚;替加环素有致死危险。 FDA limits acetaminophen; risk of death with tigecycline.
已发布 PubMed:效力 影响 Effectiveness of 自由贸易区 FDA's new 在柜台 过度 over-the-计数器 counter acetaminophen 警告 warning 标签 label in 改善 improving 消费者 consumer 风险 risk 知觉 perception of 肝 liver 损伤 damage.
已发布 PubMed:相对于膳食摄入的摄取时间决定了对含有植物固醇的酸奶饮料的胃肠道反应。 Time of ingestion relative to meal intake determines gastrointestinal responses to a plant sterol-containing yoghurt drink.
已发布 PubMed:di-22尿液和血清水平的Comparison of urinary and serum levels of di-22:6-双(单酰基甘油)磷酸酯是大鼠磷脂代谢的非侵入性生物标志物。 6-bis(monoacylglycerol)phosphate as noninvasive biomarkers of phospholipidosis in rats.
已发布 PubMed:基于通用提取程序从牛乳和肌肉组织中分离非甾体类抗炎药的两种多残留液相色谱串联质谱方法的开发和验证。 Development and validation of two multiresidue liquid chromatography tandem mass spectrometry methods based on a versatile extraction procedure for isolating non-steroidal anti-inflammatory drugs from bovine milk and muscle tissue.
已发布 PubMed:流通设备中使用透析适配器对乙酰氨基酚悬浮液进行溶出度测试 Dissolution testing of acetaminophen suspension using dialysis adapter in flow-through apparatus: 技术说明。 a technical note.
已发布 PubMed:利福平对小鼠对乙酰氨基酚肝毒性的影响及其机制 Effects and mechanisms of rifampin on hepatotoxicity of acetaminophen in mice.
已发布 PubMed:静脉对乙酰氨基酚在急性疼痛管理中的作用 The role of intravenous acetaminophen in acute pain management: 案例说明的评论。 a case-illustrated review.
已发布 PubMed:进食啮齿动物和毒理学研究。 Meal-feeding rodents and toxicology research.
已发布 PubMed:波哥大学龄儿童过敏性鼻炎及相关因素 Allergic rhinitis and associated factors in schoolchildren from Bogota, 哥伦比亚。 Colombia.
已发布 PubMed:静脉对乙酰氨基酚的临床和经济证据。 Clinical and economic evidence for intravenous acetaminophen.
已发布 PubMed:当一种药物影响2位患者 When one drug affects 2 patients: 治疗非劳力性疼痛的药物综述 a review of medication for the management of nonlabor-related pain, 镇静剂 sedation, 感染 infection, 和住院孕妇的高血压。 and hypertension in the hospitalized pregnant patient.
已发布 PubMed:混乱 Confusion: 对乙酰氨基酚的剂量变化基于成 没有证据。 acetaminophen dosing changes based on NO evidence in adults.
已发布 PubMed:处方对乙酰氨基酚的摄入与肝损伤和死亡有关。 Prescription acetaminophen ingestions associated with hepatic injury and death.
已发布 PubMed:羽毛粉 Feather meal: 以前无法识别的多种药品和个 护理产品(ppcps)重新进入食品供应的途径。 a previously unrecognized route for reentry into the food supply of multiple pharmaceuticals and personal care products (PPCPs).
已发布 PubMed:蒲公英的叶提取物的抗氧化特性参与了对乙酰氨基酚对小鼠肝毒性的保护作用。 Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice.
已发布 PubMed:赛义德 NSAIDs: 禁食或禁食后服用? take with food or after fasting?
已发布 PubMed:重复服用对乙酰氨基酚对儿童的毒性 Toxicity from repeated doses of acetaminophen in children: 报告病例的因果关系和剂量评估。 assessment of causality and dose in reported cases.
已发布 PubMed:羽扇豆酚可防止对乙酰氨基酚诱导的氧化应激和大鼠原代肝细胞死亡。 Lupeol protects against acetaminophen-induced oxidative stress and cell death in rat primary hepatocytes.
已发布 PubMed:对乙酰氨基酚和乙酰半胱氨酸剂量和持续时间 Acetaminophen and acetylcysteine dose and duration: 过去 past, 现在和未来。 present and future.
已发布 PubMed:绿茶提取物可以增强对乙酰氨基酚引起的小鼠肝毒性。 Green tea extract can potentiate acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:波哥大6-7岁和13-14岁小学生的鼻结膜炎患病率及相关因素 Rhinoconjunctivitis prevalence and associated factors in school children aged 6-7 and 13-14 years old in Bogota, 哥伦比亚。 Colombia.
已发布 PubMed:地下水中的药品和个 护理产品 Pharmaceutical and personal care products in groundwater, 地下排水 subsurface drainage, 泥 soil, 和小麦籽粒 and wheat grain, 在将城市生物固体大量应用到田间之后。 following a high single application of municipal biosolids to a field.
已发布 PubMed:姜黄素暴露可调节多种促凋亡和抗凋亡信号通路,以拮抗对乙酰氨基酚诱导的毒性。 Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity.
已发布 PubMed:儿科镇痛临床试验设计 Pediatric analgesic clinical trial designs, 措施 measures, 和外推 and extrapolation: fda科学研讨会的报告。 report of an FDA scientific workshop.
已发布 PubMed:利拉鲁肽 Liraglutide: 对胃排空的短暂影响-对体重的持久影响 short-lived effect on gastric emptying -- long lasting effects on body weight.
已发布 PubMed:羽衣甘蓝摄入对大鼠对乙酰氨基酚的药代动力学的影响。 Effects of kale ingestion on pharmacokinetics of acetaminophen in rats.
已发布 PubMed: 经fda批准的可保护哺乳动物橙花元免受葡萄糖毒性影响的药物可延缓依赖cbp cbp的衰老并防止蛋白毒性。
已发布 PubMed:鉴定可诊断肝毒性的大鼠尿微核素谱。 Identification of urinary microRNA profiles in rats that may diagnose hepatotoxicity.
已发布 PubMed:舒马普坦-萘普生和丁比妥 Sumatriptan-naproxen and butalbital: 双盲 a double-blind, 安慰剂对照的交叉研究。 placebo-controlled crossover study.
已发布 PubMed:Acetaminophen: 消除疼痛和发烧。 beyond pain and Fever-relieving.
已发布 PubMed:对乙酰氨基酚暴露后小鼠肝脏蛋白谷胱甘肽化的变化。 Changes in mouse liver protein glutathionylation after acetaminophen exposure.
已发布 PubMed:在肥胖和禁食引起的脂肪变性中,小鼠肝脏中的udp-葡萄糖醛酸转移酶表达增加。 UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosis.
已发布 PubMed:穿心莲和紫草的保肝活性。 Hepatoprotective activity of Andrographis paniculata and Swertia chirayita.
已发布 PubMed:一种新的快速吸收的小儿扑热息痛悬浮液。一项六向交叉药代动力学研究,比较了新的对乙酰氨基酚悬浮液与两种市售儿科制剂对乙酰氨基酚的吸收速率和程度。 A new rapidly absorbed paediatric paracetamol suspension. A six-way crossover pharmacokinetic study comparingthe rate and extent of paracetamol absorption from a new paracetamol suspension with two marketed paediatric formulations.
已发布 PubMed:对乙酰氨基酚的误解以及潜在的意外滥用。 Misunderstanding and potential unintended misuse of acetaminophen among adolescents and young adults.
已发布 PubMed:拼写 Spell out 'acetaminophen' for 耐心 患者 patients' 清酒 sake, 小组说。 group says.
已发布 PubMed:处方获得的对乙酰氨基酚使用和潜在的过度使用燕鸥 Prescription-acquired acetaminophen use and potential overuse patterns: 2001-2008.
已发布 PubMed:拉曼光谱的标准化,可在不同仪器之间传输光谱库。 Standardization of Raman spectra for transfer of spectral libraries across different instruments.
已发布 PubMed:使用新型体外动态胃模型预测不同口服胶囊壳类型的 体内性能。 Predicting the human in vivo performance of different oral capsule shell types using a novel in vitro dynamic gastric model.
已发布 PubMed:健康素养作为争议 Health literacy as controversy: an 线上 online comm单元 unity's 讨论区 discussion of the U.S. Food and 药品 Drug ug 管理 Administration acetaminophen 建议 recommendations.
已发布 PubMed: ug ugt1a6和ug ugt2b15多态性和对乙酰氨基酚共轭响应随机 , 精选水果和蔬菜的控制饮食。 controlled diet of select fruits and vegetables.
已发布 PubMed:对乙酰氨基酚的同时分析 Simultaneous analysis of acetaminophen, 对氨基苯酚和阿司匹林代谢产物通过亲水相互作用和强阴离子交换毛细管液相色谱法结合安培检测。 p-aminophenol and aspirin metabolites by hydrophilic interaction and strong anion exchange capillary liquid chromatography coupled to amperometric detection.
已发布 PubMed:使用药代动力学模型来确定药物和食物对犬胃肠道运输的影响。 Using pharmacokinetic modeling to determine the effect of drug and food on gastrointestinal transit in dogs.
已发布 PubMed:对乙酰氨基酚毒性的简化n-乙酰半胱氨酸给药方案的评价。 Evaluation of a simplified N-acetylcysteine dosing regimen for the treatment of acetaminophen toxicity.
已发布 PubMed:内源性释放的glp-1不足以改变狗的餐后血糖调节。 Endogenously released GLP-1 is not sufficient to alter postprandial glucose regulation in the dog.
已发布 PubMed:fda限制处方对乙酰氨基酚。但要警惕非处方对乙酰氨基酚 FDA limits prescription acetaminophen. But be vigilant about over-the-counter acetaminophen, 太。 too.
已发布 PubMed:维生素d₃补充对 体受试者葡萄糖产生途径的影响。 Effect of supplementation with vitamin D₃ on glucose production pathways in human subjects.
已发布 PubMed:大黄酸可防止对乙酰氨基酚引起的肝和肾毒性。 Rhein protects against acetaminophen-induced hepatic and renal toxicity.
已发布 PubMed:为什么要有食物药品管理局(fda)将对乙酰氨基酚处方药限制为每剂325毫克? Why has the Food & Drug Administration (FDA) limited acetaminophen prescription products to 325 milligrams per dosage?
已发布 PubMed:平板模压机对通过挤出/滚圆法制造药物颗粒的适用性。 Suitability of a flat die press for the manufacture of pharmaceutical pellets by extrusion/spheronization.
已发布 PubMed: 提取物 Kava extract, 缓解焦虑的草药替代品 an herbal alternative for anxiety relief, 增强对乙酰氨基酚诱导的大鼠肝细胞毒性。 potentiates acetaminophen-induced cytotoxicity in rat hepatic cells.
已发布 PubMed:随机的 A randomized, 双盲 a double-blind, 安慰剂对照 placebo-controlled, 多中心 multicenter, 两种腹腔镜手术后对乙酰氨基酚静脉给药的重复剂量研究。 repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
已发布 PubMed:美国对乙酰氨基酚过量相关急诊室就诊和住院的特征。 Characterization of acetaminophen overdose-related emergency department visits and hospitalizations in the United States.
已发布 PubMed:对乙酰氨基酚对砷暴露大鼠肾脏中活性氧和一氧化氮氧化还原信号的影响 Effects of acetaminophen on reactive oxygen species and nitric oxide redox signaling in kidney of arsenic-exposed rats.
已发布 PubMed:磁共振成像在药物研究中的可能应用。 A possible application of magnetic resonance imaging for pharmaceutical research.
已发布 PubMed:对乙酰氨基酚的治疗用途和与之相关的风险 The therapeutic applications of and risks associated with acetaminophen use: 审查和更新。 a review and update.
已发布 PubMed:直肠对乙酰氨基酚与布比卡因的 周围浸润对小儿腺 切除术后的镇痛作用。 Rectal acetaminophen versus peritonsillar infiltration of bupivacaine for postoperative analgesia after adenotonsillectomy in children.
已发布 PubMed:对乙酰氨基酚诱导原代肝细胞凋亡过程中益生菌对bax / bcl-2和胱天蛋白酶的调节 Modulation of Bax/Bcl-2 and caspases by probiotics during acetaminophen induced apoptosis in primary hepatocytes.
已发布 PubMed:离子迁移谱法可快速分析非处方药和饮料。 Ion mobility spectrometry for the rapid analysis of over-the-counter drugs and beverages.
已发布 PubMed:槲皮素和姜黄素对扑热息痛诱导的组织学变化的潜在保护作用 Potential protective effects of quercetin and curcumin on paracetamol-induced histological changes, 氧化应激 oxidative stress, 大鼠肝肾功能受损和血液毒性。 impaired liver and kidney functions and haematotoxicity in rat.
已发布 PubMed:打包 Bundle up: it's 痛苦 痛 painful out 那里 there--the 案件 case for 对乙酰氨基酚 类药物 opioid-acetaminophen 组合 组合 combinations.
已发布 PubMed:血液中的基因组指标可预测药物性肝损伤。 Genomic indicators in the blood predict drug-induced liver injury.
已发布 PubMed:在治疗自闭症牙科患者方面存在争议的问题。 Controversial issues in treating the dental patient with autism.
已发布 PubMed:增加对乙酰氨基酚诱导的小鼠巨噬细胞毒性中线粒体应激和线粒体呼吸酶活性的调节。 Increased mitochondrial stress and modulation of mitochondrial respiratory enzyme activities in acetaminophen-induced toxicity in mouse macrophage cells.
已发布 PubMed:补充胸腺醌可逆转对乙酰氨基酚引起的氧化应激 Thymoquinone supplementation reverses acetaminophen-induced oxidative stress, 一氧化氮的产生和小鼠肝脏能量的下降。 nitric oxide production and energy decline in mice liver.
已发布 PubMed:白花蛇舌草叶提取物对乙酰氨基酚引起的大鼠肝损伤的抗氧化活性和肝保护作用 Antioxidant activity and hepatoprotective property of leaf extracts of Boerhaavia diffusa Linn against acetaminophen-induced liver damage in rats.
已发布 PubMed:扑热息痛片剂弹射过程中弹性松弛的有害后果。 Detrimental consequences of the paracetamol tablet elastic relaxation during ejection.
已发布 PubMed:对michna等 的评论。 Commentary to Michna et al.: 房间里的大象 The elephant in the room: 氢可酮/对乙酰氨基酚组合化合物及其取代作用。 hydrocodone/acetaminophen combination compounds and the substitution effect.
已发布 PubMed:去除 /对乙酰氨基酚联合处方止痛药 Removal of opioid/acetaminophen combination prescription pain medications: 评估肝毒性的证据以及去除这些药物的后果。 assessing the evidence for hepatotoxicity and consequences of removal of these medications.
已发布 PubMed:一项由阿比多尔和对乙酰氨基酚组成的抗 药物组合在大鼠中进行的为期4周的口服毒性研究。 A 4-week oral toxicity study of an antiviral drug combination consisting of arbidol and acetaminophen in rats.
已发布 PubMed:芙蓉水提取物通过减少小鼠实验模型中的细胞死亡和氧化应激来降低对乙酰氨基酚引起的急性肝损伤。 Aqueous extract of Hibiscus sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models.
已发布 PubMed:用药风险必须与收益相平衡 Medication risk must be balanced with benefit, 不害怕。 not fear.
已发布 PubMed:fda建议限制对乙酰氨基酚(对乙酰氨基酚)的肝毒性 FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): 他们合理吗? are they reasonable?
已发布 PubMed:[对乙酰氨基酚 [Acetaminophen: 毕竟不是那么无害!]。 not so harmless after all!].
已发布 PubMed:Acetaminophen: 老朋友-新规则。 old friend--new rules.
已发布 PubMed:丙氧芬和老年 的疼痛管理。 Propoxyphene and pain management in the elderly.
已发布 PubMed:膳食 藻对d-半乳糖胺和对乙酰氨基酚引起的肝损伤的保护作用。 Protection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuries.
已发布 PubMed:[原发性头痛的自我用药]。 [Self-medication of primary headaches].
已发布 PubMed:对乙酰氨基酚和四氢茚并吲哚保护小鼠免受奥氮平诱导的小鼠代谢毒性。 Protection from olanzapine-induced metabolic toxicity in mice by acetaminophen and tetrahydroindenoindole.
已发布 PubMed:il-1beta显微注射到大鼠伏隔核后体内稳态变化。 Homeostatic alterations after IL-1beta microinjection into the nucleus accumbens of the rat.
已发布 PubMed:[在兽医和 类临床毒理学中的应用]。 [Application in veterinary and human clinical toxicology].
已发布 PubMed:在新的指导原则之前,止痛药的关注日益增长。 Painkiller concerns grow ahead of new guidelines.
已发布 PubMed:Acetaminophen: 旧药 old drug, 新的警告。 new warnings.
已发布 PubMed:内在性与特异性药物诱导的肝毒性-两个小 还是一个? Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one?
已发布 PubMed:植酸 Phytalgic, 食物补充剂 a food supplement, 与安慰剂相比,膝部或髋部骨节螺藻患者 vs placebo in patients with osteoarthritis of the knee or hip: 一项随机的双盲安慰剂对照临床试验。 a randomised double-blind placebo-controlled clinical trial.
已发布 PubMed:二甘醇对乙酰氨基酚污染的幼儿致命致命中毒-尼日利亚 Fatal poisoning among young children from diethylene glycol-contaminated acetaminophen - Nigeria, 2008-2009.
已发布 PubMed:与瘦肉相比,肥胖者混合饮食或摄入葡萄糖后肠促胰激素的分泌和二肽基肽酶-4介导的代谢 Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, 非糖尿病男性。 nondiabetic men.
已发布 PubMed:通过毒理基因组学和机器学习预测烯基苯调味剂的肝癌潜力。 Predicting the hepatocarcinogenic potential of alkenylbenzene flavoring agents using toxicogenomics and machine learning.
已发布 PubMed:荆条亚麻的药代动力学相互作用。 &扑热息痛。 Pharmacokinetic-interaction of Vitex negundo Linn. & paracetamol.
已发布 PubMed:艰难的平衡-疼痛管理 A difficult balance--pain management, 药物安全 drug safety, 和自由贸易区。 and the FDA.
已发布 PubMed:反复接触砷对乙酰氨基酚诱导的雄性大鼠肝脏氧化应激的影响。 Influence of repeated preexposure to arsenic on acetaminophen-induced oxidative stress in liver of male rats.
已发布 PubMed:在学术医院的儿科重症监护室使用标签外用药。 Off-label medication use in an academic hospital pediatric critical care unit.
已发布 PubMed:风变 Changing winds: 实践对乙酰氨基酚法规的含义。 practice implications of acetaminophen regulations.
已发布 PubMed:。 。 。 fda可能会限制含对乙酰氨基酚的药物的销售。 。 。 . . . FDA may limit sales of acetaminophen-containing medications. . .
已发布 PubMed:肌肽和组氨酸对乙酰氨基酚引起的肝损伤的保护作用。 Protective effects from carnosine and histidine on acetaminophen-induced liver injury.
已发布 PubMed:fda对乙酰氨基酚咨询委员会会议-美国对乙酰氨基酚的未来是什么?委员会成员的观点。 The FDA Acetaminophen Advisory Committee Meeting - what is the future of acetaminophen in the United States? The perspective of a committee member.
已发布 PubMed:代谢组学研究尿液中对乙酰氨基酚和代谢物及其与毒性的关系。 Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics.
已发布 PubMed:自由贸易区 FDA's acetaminophen 会议 meeting 火花 sparks 混乱 confusion, 不确定。 uncertainty.
已发布 PubMed:fda关注药物和肝损害 FDA focuses on drugs and liver damage: 对乙酰氨基酚的标签和其他变化。 labeling and other changes for acetaminophen.
已发布 PubMed: 对乙酰氨基酚安全性-deja deja vu vu。
已发布 PubMed:去氢姜黄素的镇痛作用。 The analgesic effect of decursinol.
已发布 PubMed:特定于器官的警告;内部止痛药 Organ-specific warnings; internal analgesic, 解热的 antipyretic, 非处方的 类使用的抗风湿药产品;最后的专着。最终规则。 and antirheumatic drug products for over-the-counter human use; final monograph. Final rule.
已发布 PubMed:将脱水的市政生物固体应用于农业领域后,药品和个 护理产品的径流。 Runoff of pharmaceuticals and personal care products following application of dewatered municipal biosolids to an agricultural field.
已发布 PubMed:对乙酰氨基酚和塞来昔布对大鼠正畸牙移动和橙花元活化的影响 Effects of short-term acetaminophen and celecoxib treatment on orthodontic tooth movement and neuronal activation in rat.
已发布 PubMed:紫色肉甘薯中的花色苷成分对小鼠对乙酰氨基酚引起的肝损伤的肝保护作用。 Hepatoprotective effects of an anthocyanin fraction from purple-fleshed sweet potato against acetaminophen-induced liver damage in mice.
已发布 PubMed: 从1999年至2002年对与使用罗非昔布 rofecoxib相关的严重不良事件进行售后监测。
已发布 PubMed:在地面铺开并向农业领域注入脱水的市政生物固体后,用于瓷砖排水的制药和个 护理产品。 Pharmaceutical and personal care products in tile drainage following surface spreading and injection of dewatered municipal biosolids to an agricultural field.
已发布 PubMed:姜黄素可预防对乙酰氨基酚对大鼠的氧化性肾损害。 Curcumin prevents oxidative renal damage induced by acetaminophen in rats.
已发布 PubMed:急性对乙酰氨基酚诱发的小鼠肝损伤早期的肝脏抗氧化能力。 Liver antioxidant capacity in the early phase of acute paracetamol-induced liver injury in mice.
已发布 PubMed:燕麦麸质饮料的粘度会影响健康 的胃肠激素反应。 Viscosity of oat bran-enriched beverages influences gastrointestinal hormonal responses in healthy humans.
已发布 PubMed: 对β-葡聚糖抗乙酰氨基酚诱导的小鼠毒性的功效的影响。 Effect of gamma irradiation on the efficacy of beta-glucan against acetaminophen induced toxicity in mice.
已发布 PubMed:多种肝毒性研究中反式硫途径的评估 Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies.
已发布 PubMed:小鼠体内白和粉红葡萄柚汁与对乙酰氨基酚(扑热息痛)的相互作用。 Interaction of white and pink grapefruit juice with acetaminophen (paracetamol) in vivo in mice.
已发布 PubMed:乙酰丙酮对乙酰氨基酚毒性的安全性和有效性。 Safety and effectiveness of acetadote for acetaminophen toxicity.
已发布 PubMed:I 采取 take acetaminophen to 帮帮我 help with my 节螺藻 arthritis 痛 pain. is Is it 好的 okay for me to 喝 drink 葡萄酒 wine 而 while I'm 服用 taking 这个 this 药物? 药物 medication?
已发布 PubMed:拉曼检测对乙酰氨基酚多态性转化的差示扫描量热法。 Raman detected differential scanning calorimetry of polymorphic transformations in acetaminophen.
已发布 PubMed:藻类粗硫酸化多糖对乙酰氨基酚引起的大鼠毒性的影响 Effect of crude sulphated polysaccharide from brown algae against acetaminophen-induced toxicity in rats.
已发布 PubMed:酿酒酵母发酵物对乙酰氨基酚引起的小鼠肝损伤的保护作用。 Protective effect of a fermented substance from Saccharomyces cerevisiae on liver injury in mice caused by acetaminophen.
已发布 PubMed:提取物对氧化应激诱导的大鼠不同器官毒性的影响 Effects of tomato extract on oxidative stress induced toxicity in different organs of rats.
已发布 PubMed:毛状裂殖酵母糖蛋白对乙酰氨基酚所致肝损伤的作用 Effect of a glycoprotein from Hizikia fusiformis on acetaminophen-induced liver injury.
已发布 PubMed:红藻紫菜蛋白对大鼠对乙酰氨基酚所致肝损伤的化学保护作用 Chemoprotective effects of a protein from the red algae Porphyra yezoensis on acetaminophen-induced liver injury in rats.
已发布 PubMed:药物引起的线粒体损害和疾病。 Medication-induced mitochondrial damage and disease.
已发布 PubMed:妊娠和哺乳期非处方药概述。 An overview of over the counter drugs in pregnancy and lactation.
已发布 PubMed:辣木兰通过恢复谷胱甘肽水平来防止对乙酰氨基酚引起的肝损伤。 Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level.
已发布 PubMed:曲马多缓释剂用于慢性疼痛的治疗。 Tramadol extended-release in the management of chronic pain.
已发布 PubMed:使用nmr和uplc / ms对接受急,慢性剂量对乙酰氨基酚的大鼠尿液的代谢组学评估。 Metabonomics evaluation of urine from rats given acute and chronic doses of acetaminophen using NMR and UPLC/MS.
已发布 PubMed:近红外光谱和广义二维相关光谱法分析含氮芳香药物的结构。 Structure analysis of aromatic medicines containing nitrogen using near-infrared spectroscopy and generalized two-dimensional correlation spectroscopy.
已发布 PubMed:施用城市生物固体后,用于排水的药品和个 护理产品。 Pharmaceutical and personal care products in tile drainage following land application of municipal biosolids.
已发布 PubMed:细胞色素c Cytochrome c: 药物性肝损伤的非侵入性生物标志物。 a non-invasive biomarker of drug-induced liver injury.
已发布 PubMed:2007年药物性肝损伤。 Drug-induced liver injury in 2007.
已发布 PubMed:生物固体在农业领域的应用之后,药品和个 护理产品的径流。 Runoff of pharmaceuticals and personal care products following application of biosolids to an agricultural field.
已发布 PubMed:食品中咖啡因及相关化合物的测定 Determination of caffeine and associated compounds in food, 饮料 beverages, 天然产物 natural products, 药品 pharmaceuticals, 和化妆品采用胶束电动毛细管色谱法。 and cosmetics by micellar electrokinetic capillary chromatography.
已发布 PubMed: cuscusa chinensis的纳米颗粒制剂可防止对乙酰氨基酚诱导的大鼠肝毒性。
已发布 PubMed: 的透明质酸对乙酰氨基酚引起的急性肝毒性的影响。 Effect of gamma irradiated hyaluronic acid on acetaminophen induced acute hepatotoxicity.
已发布 PubMed:片剂在粘性介质中的崩解和药物溶解 Tablet disintegration and drug dissolution in viscous media: 扑热息痛ir片。 paracetamol IR tablets.
已发布 PubMed:慢性便秘的危险因素以及止痛药的可能作用。 Risk factors for chronic constipation and a possible role of analgesics.
已发布 PubMed:碳酸氢钠对乙酰氨基酚泡腾粉新配方与对乙酰氨基酚片的相对生物利用度 Relative bioavailability of new formulation of paracetamol effervescent powder containing sodium bicarbonate versus paracetamol tablets: 一项针对进食对象的比较药代动力学研究。 a comparative pharmacokinetic study in fed subjects.
已发布 PubMed:对乙酰氨基酚毒性 Acetaminophen toxicity: 改变对社会/医学问题的看法。 changing perceptions on a social/medical issue.
已发布 PubMed:同时分光光度法测定扑热息痛 Simultaneous spectrophotometric determination of paracetamol, 化学计量学方法测定布洛芬和咖啡因的含量。 ibuprofen and caffeine in pharmaceuticals by chemometric methods.
已发布 PubMed:(iii)-氢氧化铁多麦芽糖复合物与常用药物之间的相互作用/模拟和体外研究。 Interactions between iron(III)-hydroxide polymaltose complex and commonly used drugs / simulations and in vitro studies.
已发布 PubMed:系统在对乙酰氨基酚诱导的小鼠肝毒性中的作用。 Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:姜黄可乐可通过增强肝脏的抗氧化剂状态来防止对乙酰氨基酚引起的急性肝毒性。 Zingiber officinale Roscoe prevents acetaminophen-induced acute hepatotoxicity by enhancing hepatic antioxidant status.
已发布 PubMed:通过化学图像的宏观像素分析来表征药品。 Drug product characterization by macropixel analysis of chemical images.
已发布 PubMed:小剂量扑热息痛对家兔肝脏的影响。 The influence of small doses of paracetamol on rabbit liver.
已发布 PubMed:读取其他安全信息对计划使用非处方镇痛药的影响。 Effect of reading additional safety information on planned use of over-the-counter analgesics.
已发布 PubMed:推荐剂量对乙酰氨基酚的安全性。 Safety of recommended doses of paracetamol.
已发布 PubMed:扁桃vernonia对对乙酰氨基酚引起的小鼠肝损伤的肝保护和抗氧化活性。 Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice.
已发布 PubMed:对乙酰氨基酚(对乙酰氨基酚)中毒。 Paracetamol (acetaminophen) poisoning.
已发布 PubMed:胰岛素样生长因子i通过erk1 / 2激活对抗对乙酰氨基酚诱导的肝细胞死亡的化学保护作用。 Chemoprotective effect of insulin-like growth factor I against acetaminophen-induced cell death in Chang liver cells via ERK1/2 activation.
已发布 PubMed:体外诱变潜能及其对共同给药药物跨越红景天及其强化组分的caco-2细胞单层的通透性的影响。 In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions.
已发布 PubMed:5岁女孩对糖果中的偶氮染料不耐受后会产生多种化学敏感性。 Multiple chemical sensitivities following intolerance to azo dye in sweets in a 5-year-old girl.
已发布 PubMed:碳酸氢钠对乙酰氨基酚片的镇痛作用 Onset of analgesia of a paracetamol tablet containing sodium bicarbonate: 双盲 a double-blind, 成 急性咽喉患者的安慰剂对照研究。 placebo-controlled study in adult patients with acute sore throat.
已发布 PubMed:柴胡叶靛灰叶/野靛草的抗氧化和体外保肝活性。 Antioxidative and in vitro hepatoprotective activity of Bupleurum kaoi leaf infusion.
已发布 PubMed:氘水和对乙酰氨基酚早餐前后肝糖原动力学的非侵入性分析。 Noninvasive analysis of hepatic glycogen kinetics before and after breakfast with deuterated water and acetaminophen.
已发布 PubMed: 体运动器官不同阶段进食后循环生长素释放肽水平升高。 Circulating ghrelin levels after food intake during different phases of the migrating motor complex in man.
已发布 PubMed:超群的转移 The Diversion of Ultram, 超 Ultracet, 和通用曲马多盐酸盐。 and generic tramadol HCL.
已发布 PubMed:姜及其植物化学物质的化学预防作用的最新进展。 Update on guidelines for the treatment of chronic musculoskeletal pain.
已发布 PubMed:今天的疼痛管理-我们学到了什么? Pain management today - what have we learned?
已发布 PubMed:共振光谱法作为一种过程分析技术,可快速,准确地识别药片。 Acoustic-resonance spectrometry as a process analytical technology for rapid and accurate tablet identification.
已发布 PubMed:ods大鼠体内谷胱甘肽水平的升高并不能进一步抑制膳食二十二碳六烯酸诱导的肝脂质过氧化物的产生。 Dietary docosahexaenoic acid-induced generation of liver lipid peroxides is not suppressed further by elevated levels of glutathione in ODS rats.
已发布 PubMed:乙酰丙酮(静脉乙酰半胱氨酸) Acetadote (intravenous acetylcysteine): 不良反应比口服乙酰半胱氨酸更明显。 adverse effects more significant than with oral acetylcysteine.
已发布 PubMed:处方非甾体类抗炎药的循证方法。第三届加拿大共识会议。 An evidence-based approach to prescribing nonsteroidal antiinflammatory drugs. Third Canadian Consensus Conference.
已发布 PubMed:美国对乙酰氨基酚(盲肠)相关药物过量的估计。 Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States.
已发布 PubMed:皮肤接触对氨基苯酚或对苯二胺后的血浆/血液药代动力学和代谢。 Plasma/blood pharmacokinetics and metabolism after dermal exposure to para-aminophenol or para-phenylenediamine.
已发布 PubMed: 胃排空对餐后生长素释放肽 ghrelin反应的影响。
已发布 PubMed:s-烯丙基半胱氨酸和s-丙基半胱氨酸对乙酰氨基酚诱导的小鼠肝毒性的保护作用。 Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice.
已发布 PubMed:使用不同方法在禁食和进食状态下的体内/体外相关水平 A level A in vitro/in vivo correlation in fasted and fed states using different methods: 应用于固体速释口服剂型。 applied to solid immediate release oral dosage form.
已发布 PubMed:新生儿侵入性手术期间进行镇痛和局部麻醉。 Analgesia and local anesthesia during invasive procedures in the neonate.
已发布 PubMed:胰十二指肠切除术后延迟胃排空和肠道激素。 Delayed gastric emptying and intestinal hormones following pancreatoduodenectomy.
已发布 PubMed:他尼洛尔双峰现象很可能是由肠道管腔摄取后的系统前处理引起的。 The talinolol double-peak phenomenon is likely caused by presystemic processing after uptake from gut lumen.
已发布 PubMed:在体外可以预测对乙酰氨基酚产物在犬食性胃中的延迟溶解,但它不会影响血浆水平的发作。 The delayed dissolution of paracetamol products in the canine fed stomach can be predicted in vitro but it does not affect the onset of plasma levels.
已发布 PubMed:口服苯暴露28天后大鼠肝脏中基因表达变化的毒理基因组分析。 Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure.
已发布 PubMed:干扰素-β1b用于多发性硬化症。 Interferon-beta1b for multiple sclerosis.
已发布 PubMed:临床前测试策略是否有助于预测 的肝毒性潜力? Do preclinical testing strategies help predict human hepatotoxic potentials?
已发布 PubMed:n-乙酰半胱氨酸治疗儿童对乙酰氨基酚急性毒性的最新进展。 An update of N-acetylcysteine treatment for acute acetaminophen toxicity in children.
已发布 PubMed:肠降血糖素在1型糖尿病中的血糖作用 Glycaemic effects of incretins in Type 1 diabetes mellitus: 简洁的评论 a concise review, 重点研究 类。 with emphasis on studies in humans.
已发布 PubMed:薄层色谱和质谱联用解吸电喷雾电离。 Thin-layer chromatography and mass spectrometry coupled using desorption electrospray ionization.
已发布 PubMed:药物性肝病。 Drug-induced liver disease.
已发布 PubMed:网状叶霉(叶绿藻)的抗肝毒性对乙酰氨基酚诱导的实验大鼠的肝毒性。 Antihepatotoxic nature of Ulva reticulata (Chlorophyceae) on acetaminophen-induced hepatoxicity in experimental rats.
已发布 PubMed:口服葡萄糖摄入对胃肌电活动和胃排空的影响。 Effects of oral glucose intake on gastric myoelectrical activity and gastric emptying.
已发布 PubMed:孕期药物安全的上市后监督 Postmarketing surveillance for drug safety in pregnancy: 术语学信息服务项目的组织。 the Organization of Teratology Information Services project.
已发布 PubMed:肝药物不良反应 Adverse hepatic drug reactions: 炎症发作的结果和贡献者。 inflammatory episodes as consequence and contributor.
已发布 PubMed:太赫兹光谱在制药科学中的应用。 Applications of terahertz spectroscopy to pharmaceutical sciences.
已发布 PubMed:紫菀对对乙酰氨基酚引起的大鼠肝损伤的保护作用的评价 Evaluation of the protective efficacy of Asteracantha longifolia on acetaminophen-induced liver damage in rats.
已发布 PubMed:茶色素对小鼠对乙酰氨基酚引起的肝损伤的预防作用。 Preventive effect of Thea sinensis melanin against acetaminophen-induced hepatic injury in mice.
已发布 PubMed:对乙酰氨基酚和美国急性肝衰竭研究组 Acetaminophen and the U.S. Acute Liver Failure Study Group: 降低肝衰竭的风险。 lowering the risks of hepatic failure.
已发布 PubMed:日粮对乙酰氨基酚致小鼠肝毒性24 节律的影响 Influence of feeding schedule on 24-h rhythm of hepatotoxicity induced by acetaminophen in mice.
已发布 PubMed:宝饮料(芙蓉水提取物)对 体志愿者对乙酰氨基酚药代动力学的影响 Effect of zobo drink (Hibiscus sabdariffa water extract) on the pharmacokinetics of acetaminophen in human volunteers.
已发布 PubMed:一个动态的 工胃肠系统,用于研究在各种生理条件下口服给药药物剂型的行为。 A dynamic artificial gastrointestinal system for studying the behavior of orally administered drug dosage forms under various physiological conditions.
已发布 PubMed:基础基因表达谱的比较和肝癌致癌因子对培养的原代 肝细胞和hepg2细胞基因表达的影响。 Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
已发布 PubMed:[怀孕和哺乳期偏头痛 [Migraine during pregnancy and lactation: 急性发作的治疗和非药物预防策略] treatment of the acute attack and non-pharmacological prophylactic strategies].
已发布 PubMed:fda启动otc止痛产品运动。 FDA launches campaign on OTC pain relief products.
已发布 PubMed:急性疼痛的止痛药 Analgesics for acute pain: 会议 Meeting the 联合的 United 状态 States Food and 药品 Drug ug 管理 Administration's 要求 requirements for 证明 proof of 功效 efficacy.
已发布 PubMed:肝移植中心对严重暴发性肝衰竭患者进行肝透析治疗的经验 A liver transplant center experience with liver dialysis in the management of patients with fulminant hepatic failure: 初步报告。 a preliminary report.
已发布 PubMed:父母对舒马曲坦鼻喷雾剂对儿童偏头痛的满意度。 Parental satisfaction with sumatriptan nasal spray in childhood migraine.
已发布 PubMed:对乙酰氨基酚治疗营养不良大鼠肝酶的改变 [Modification of liver enzymes in undernourished rats treated with acetaminophen].
已发布 PubMed:和冰淇淋对扑热息痛对高表面活性炭吸附能力的影响 The effect of food and ice cream on the adsorption capacity of paracetamol to high surface activated charcoal: 体外研究。 in vitro studies.
已发布 PubMed:评估猫狗胃排空率的方法的综述 A review of methods for assessment of the rate of gastric emptying in the dog and cat: 1898-2002.
已发布 PubMed:氟哌啶醇的在线不良事件。 An online misadventure with haloperidol.
已发布 PubMed:通过降低细胞内谷胱甘肽水平的药物增强氯喹在啮齿动物疟疾中的抗疟作用。 Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels.
已发布 PubMed:对乙酰氨基酚作为大鼠的术后镇痛药。 Acetaminophen as a postsurgical analgesic in rats.
已发布 PubMed:食物或水缺乏对小牛扑热息痛药代动力学的影响。 The effect of food or water deprivation on paracetamol pharmacokinetics in calves.
已发布 PubMed:对乙酰氨基酚肝毒性。 Acetaminophen hepatotoxicity.
已发布 PubMed:食品中那格列奈的摄入对健康受试者胃排空率的影响。 The effect of nateglinide taken with food on gastric emptying rates in healthy subjects.
已发布 PubMed:吸入性对乙酰氨基酚中毒用吸入性正乙酰半胱氨酸稳定性和微生物学。 Stability and microbiology of inhalant N-acetylcysteine used as an intravenous solution for the treatment of acetaminophen poisoning.
已发布 PubMed:妊娠期非处方药。 Over-the-counter medications in pregnancy.
已发布 PubMed:西班牙急诊室急性中毒国家多中心研究。 National multicentre study of acute intoxication in emergency departments of Spain.
已发布 PubMed:给予一系列不同的脂肪,以血浆对乙酰氨基酚浓度测量后,大鼠胃排空。 Gastric emptying in rats following administration of a range of different fats measured as acetaminophen concentration in plasma.
已发布 PubMed:新的数学模型,用于准确描述高热量流质餐后口服对乙酰氨基酚的吸收动力学。 New mathematical model for accurate description of absorption kinetics of paracetamol given orally with a high calorie liquid meal.
已发布 PubMed:食对食蟹猴液体胃肠道运输的影响 Effect of food on gastrointestinal transit of liquids in cynomolgus monkeys.
已发布 PubMed:未喂食食蟹猴体内液体的胃肠道转运。 Gastrointestinal transit of liquids in unfed cynomolgus monkeys.
已发布 PubMed:缓解山松甲虫(鞘翅目)的推挽策略 The protective effects of Propolis on hepatic injury and its mechanism.
已发布 PubMed:对乙酰氨基酚作为大鼠的术后镇痛药 Acetaminophen as a postsurgical analgesic in rats: 切实解决新恐惧症。 a practical solution to neophobia.
已发布 PubMed:高压电容耦合非接触电导率检测,用于微芯片毛细管电泳。 High-voltage capacitively coupled contactless conductivity detection for microchip capillary electrophoresis.
已发布 PubMed:草药 Herbal medication: 与止痛药发生不良相互作用的潜力。 potential for adverse interactions with analgesic drugs.
已发布 PubMed:通过共同摄取固体来延迟胃液的胃排空 Gastric emptying of liquids is delayed by co-ingesting solids: 一项使用唾液扑热息痛浓度的研究。 a study using salivary paracetamol concentrations.
已发布 PubMed:大鼠和 类肝细胞生产胞内35s-谷胱甘肽的方法,用于定量异种生物反应性中间体。 Production of intracellular 35S-glutathione by rat and human hepatocytes for the quantification of xenobiotic reactive intermediates.
已发布 PubMed:尽管每年有450 死亡,但fda未能降低扑热息痛的可及性。 FDA fails to reduce accessibility of paracetamol despite 450 deaths a year.
已发布 PubMed:adms亚麻籽油符合astm规格d 234-61t和tt-l-215-a的要求。科学沸腾符合ASTM规格d 260-61t类型1和联邦规格tt-l-00190c。科学双煮比科学双煮包含更多的干燥剂,因此干燥更快。 A new rapidly absorbed paracetamol tablet containing sodium bicarbonate. I. A four-way crossover study to compare the concentration-time profile of paracetamol from the new paracetamol/sodium bicarbonate tablet and a conventional paracetamol tablet in fed and fasted volunteers.
已发布 PubMed:效果 影响 Effects of "中文 Chinese 芋头 yam" on 肝肾毒性 hepato-肾毒性 nephro毒性 有毒的 toxicity of acetaminophen in 老鼠 rats.
已发布 PubMed:对乙酰氨基酚过量后小鼠的细胞死亡方式 Mode of cell death after acetaminophen overdose in mice: 凋亡或肿瘤坏死? apoptosis or oncotic necrosis?
已发布 PubMed:mylotarg批准用于cd33 +急性髓细胞白血病患者。 Mylotarg approved for patients with CD33+ acute myeloid leukemia.
已发布 PubMed:与用于治疗结核病的药物具有临床上的显着相互作用。 Clinically significant interactions with drugs used in the treatment of tuberculosis.
已发布 PubMed:单独或在洗胃后使用活性炭 Activated charcoal alone or after gastric lavage: 模拟的大扑热息痛中毒。 a simulated large paracetamol intoxication.
已发布 PubMed:New, 未提及的替代方法。 non-NSAID alternative.
已发布 PubMed:氢可酮和布洛芬联用与羟考酮和对乙酰氨基酚联用在中度或重度急性下腰痛的治疗中。 Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of moderate or severe acute low back pain.
已发布 PubMed:餐后葡萄糖 Postprandial glucose, 胰岛素 insulin, 在健康受试者中对谷物产品的肠促胰岛素反应。 and incretin responses to grain products in healthy subjects.
已发布 PubMed:外源促肾上腺皮质激素释放因子对 类原发性十二指肠蠕动和食欲的影响。 Effects of exogenous corticotropin-releasing factor on antropyloroduodenal motility and appetite in humans.
已发布 PubMed:[醇与异种生物的相互作用。细胞色素p450的作用2e1]。 [Alcohol-xenobiotic interactions. Role of cytochrome P450 2E1].
已发布 PubMed:加入阿司匹林可促进癫痫后大鼠的体重增加 Weight gain in post-seized rats is facilitated by adding aspirin, 葡萄糖 glucose, 或将葡萄糖-牛磺酸-对乙酰氨基酚加到食物糊状物中。 or glucose-taurine-acetaminophen to food mush.
已发布 PubMed:关于不宜在大鼠的饮用水中使用术后镇痛药的方法。 Regarding the inadvisability of administering postoperative analgesics in the drinking water of rats (Rattus norvegicus).
已发布 PubMed:评估 体胃排空的新方法 Novel method to assess gastric emptying in humans: 颗粒胃排空试验。 the Pellet Gastric Emptying Test.
已发布 PubMed:[慢性醇滥用者使用对乙酰氨基酚 [Acetaminophen use by chronic alcohol abusers: 对于肝脏来说,治疗剂量可能太大]。 a therapeutic dose may be too much for the liver].
已发布 PubMed:(r)-和(s)-3-(苯基氨基)丙烷-1的代谢 Metabolism of (R)- and (S)-3-(phenylamino)propane-1,c57bl / 6-和a / j株小鼠中的2-二醇。鉴定对毒油综合征具有潜在毒理学意义的新代谢物。 2-diol in C57BL/6- and A/J-strain mice. Identification of new metabolites with potential toxicological significance to the toxic oil syndrome.
已发布 PubMed:布洛芬对苦参大鼠微波 行为温度调节的影响。 Ibuprofen effects on behavioral thermoregulation with microwave radiation in albino rats.
已发布 PubMed:摄入羟cut后癫痫发作活动和无反应。 Seizure activity and unresponsiveness after hydroxycut ingestion.
已发布 PubMed:食物限制对对乙酰氨基酚肝代谢的影响 The effects of food restriction in man on hepatic metabolism of acetaminophen.
已发布 PubMed:异甲基庚烯酸酯的组合的比较研究 Comparative study of a combination of isometheptene mucate, 二氯苯甲氮酮与对乙酰氨基酚和琥珀酸舒马曲坦一起治疗偏头痛。 dichloralphenazone with acetaminophen and sumatriptan succinate in the treatment of migraine.
已发布 PubMed:高效液相色谱-电喷雾串联质谱法定量 血浆中的加巴喷丁。在生物等效性研究中的应用。 Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.
已发布 PubMed:有机阴离子吲哚菁绿对乙酰氨基酚引起的肝损伤敏感性的变化。 Changes in susceptibility to acetaminophen-induced liver injury by the organic anion indocyanine green.
已发布 PubMed:效果视黄醇对肝和肾药物代谢酶的影响 The effect of retinol on hepatic and renal drug-metabolising enzymes.
已发布 PubMed:苯并噻唑对异生物素代谢酶和对乙酰氨基酚代谢的影响 Effects of benzothiazole on the xenobiotic metabolizing enzymes and metabolism of acetaminophen.
已发布 PubMed:Re: 洛克等 -肠易激综合症的危险因素。 Locke et al.--risk factors for irritable bowel syndrome.
已发布 PubMed:硝酸钠和醋氨酚联用引起的高铁血红蛋白血症。 Methemoglobinemia induced by combined use of sodium nitrate and acetoaminophen.
已发布 PubMed:老年患者偏头痛 Migraine in older patients: 病例报告和管理策略。 a case report and management strategies.
已发布 PubMed:阿司匹林和固体对乙酰氨基酚片剂在进食和禁食志愿者中的药代动力学特征比较。 Comparison of the pharmacokinetic profiles of soluble aspirin and solid paracetamol tablets in fed and fasted volunteers.
已发布 PubMed:异硫氰酸苯乙基酯对乙酰氨基酚诱导的谷胱甘肽S-转移酶表达和肝毒性的影响。 Effects of phenethylisothiocyanate on the expression of glutathione S-transferases and hepatotoxicity induced by acetaminophen.
已发布 PubMed:非处方止痛药和退烧药 Over-the-counter analgesics and antipyretics: 严格的评估。 a critical assessment.
已发布 PubMed:确定扩大的预防性治疗所带来的患者风险。 Defining patient risks from expanded preventive therapies.
已发布 PubMed:深静脉血栓形成和肺栓塞的处理。 Management of deep venous thrombosis and pulmonary embolism.
已发布 PubMed:肠易激综合征的危险因素 Risk factors for irritable bowel syndrome: 镇痛药和食物敏感性的作用。 role of analgesics and food sensitivities.
已发布 PubMed:曲马多与多种影响5-羟色胺的药物的致命组合。 Lethal combination of tramadol and multiple drugs affecting serotonin.
已发布 PubMed:胶束电动毛细管色谱法是无需样品预处理的强大药理研究工具 Micellar electrokinetic capillary chromatography as a powerful tool for pharmacological investigations without sample pretreatment: 一种精确的技术,可提供成本优势并将检测范围限制在低纳摩尔范围内。 a precise technique providing cost advantages and limits of detection to the low nanomolar range.
已发布 PubMed:曲格列酮的临床药代动力学。 Clinical pharmacokinetics of troglitazone.
已发布 PubMed:食品添加剂香兰素可增强对乙酰氨基酚和四氯化碳对啮齿动物的肝毒性。 Potentiation of paracetamol and carbon tetrachloride-induced hepatotoxicity in rodents by the food additive vanillin.
已发布 PubMed:硫酸化 Sulphation 赤字 deficit in "低功能 低 low-functioning" 自闭症 autistic 孩子们 children: 初步研究。 a pilot study.
已发布 PubMed:牙科实践中的疼痛管理 Pain management in dental practice: 曲马多与可待因组合。 tramadol vs. codeine combinations.
已发布 PubMed:直接注射血浆样品的药代动力学研究 Pharmacokinetic investigations with direct injection of plasma samples: 使用毛细管电泳(ce)可能节省的成本。 possible savings using capillary electrophoresis (CE).
已发布 PubMed:异烟肼药物与食物的相互作用。 Isoniazid drug and food interactions.
已发布 PubMed:硫酸盐和类固醇对大鼠和小鼠原代单层肝细胞培养物中对乙酰氨基酚代谢的影响 Alteration of acetaminophen metabolism by sulfate and steroids in primary monolayer hepatocyte cultures of rats and mice.
已发布 PubMed:替诺昔康和扑热息痛可待因联合口服手术后 Tenoxicam and paracetamol-codeine combination after oral surgery: 预期的 a prospective, 随机的 A randomized, 双盲 a double-blind, 安慰剂对照研究。 placebo-controlled study.
已发布 PubMed:对乙酰氨基酚混合物的修饰作用 Modifying effects of a mixture of acetaminophen, 阿司匹林 aspirin, 双嘧啶和乙酰胺对多器官启动模型的影响及其在雄性f344大鼠中的致癌性。 dipyrone and ethenzamide on a multiorgan initiation model and its carcinogenicity in male F344 rats.
已发布 PubMed:梯度洗脱毛细管电色谱和核磁共振联用。 Gradient elution capillary electrochromatography and hyphenation with nuclear magnetic resonance.
已发布 PubMed:一种使用非导电聚合物膜的新型无干扰赖氨酸生物传感器。 A new interference-free lysine biosensor using a non-conducting polymer film.
已发布 PubMed:通过在健康男性志愿者中使用含有贯叶连翘提取物的片剂进行单次和多次口服剂量研究,发现了hyperforin和类黄酮槲皮素和异鼠李素。 High-throughput flow-injection analysis of glucose and glutamate in food and biological samples by using enzyme/polyion complex-bilayer membrane-based electrodes as the detectors.
已发布 PubMed:胰高血糖素样肽1可延长肥胖男性的餐后饱腹感并减慢胃排空。 Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men.
已发布 PubMed:不同的ga保留幽门的胰十二指肠切除术后严格排空固体和液体食物。 Different gastric emptying of solid and liquid meals after pylorus-preserving pancreatoduodenectomy.
已发布 PubMed:延迟胃排空率的增加可能解释了健康饮食中添加醋的含淀粉膳食中血糖水平的改善。 Delayed gastric emptying rate may explain improved glycaemia in healthy subjects to a starchy meal with added vinegar.
已发布 PubMed:食物对溴芬酸影响 The effect of food on bromfenac, 萘普生钠 naproxen sodium, 和对乙酰氨基酚在骨科手术后的术后疼痛中。 and acetaminophen in postoperative pain after orthopedic surgery.
已发布 PubMed:药物标记物吸收与颗粒大小的关系 Drug marker absorption in relation to pellet size, 的胃动力和粘性餐。 gastric motility and viscous meals in humans.
已发布 PubMed:简单 Simple, 薄层色谱法现场检测甘油和甘油基原料中的二甘醇/乙二醇污染。 at-site detection of diethylene glycol/ethylene glycol contamination of glycerin and glycerin-based raw materials by thin-layer chromatography.
已发布 PubMed:对乙酰氨基酚的治疗错误 Therapeutic misadventures with acetaminophen: 儿童多次服用后有肝毒性。 hepatoxicity after multiple doses in children.
已发布 PubMed:基多中毒的主要原因 Principal causes of poisoning in Quito, 厄瓜多尔 Ecuador: 回顾性流行病学研究。 a retrospective epidemiology study.
已发布 PubMed:毛细管电泳测定血浆中的药物,无需样品重现性 Determination of pharmaceuticals in plasma by capillary electrophoresis without sample pretreatment reproducibility, 定量限和检测限。 limit of quantitation and limit of detection.
已发布 PubMed:静脉内口服n-乙酰半胱氨酸。 Intravenous administration of oral N-acetylcysteine.
已发布 PubMed:对乙酰氨基酚对类似于食物诱变剂的芳香胺诱导的大鼠肠癌的抑制作用。 Inhibition by acetaminophen of intestinal cancer in rats induced by an aromatic amine similar to food mutagens.
已发布 PubMed:剖宫产围手术期多模式疼痛疗法 Peri-operative multimodal pain therapy for caesarean section: 镇痛和出院适应性。 analgesia and fitness for discharge.
已发布 PubMed:无需样品预处理即可使用毛细管电泳定量血浆中对乙酰氨基酚和水杨酸精度的提高。 Quantitation of acetaminophen and salicylic acid in plasma using capillary electrophoresis without sample pretreatment. Improvement of precision.
已发布 PubMed:布洛芬和扑热息痛 Ibuprofen and paracetamol: 非处方药的相对安全性。 relative safety in non-prescription dosages.
已发布 PubMed:肾毒性药对乙酰氨基酚代谢产物的 和尿液排泄的改变。 Alteration in the biliary and urinary excretion of acetaminophen metabolites by nephrotoxicants in rats.
已发布 PubMed:细胞色素cyp1a2活性的生活方式和营养相关 Lifestyle and nutritional correlates of cytochrome CYP1A2 activity: 与血浆叶黄素和α-生育酚呈负相关。 inverse associations with plasma lutein and alpha-tocopherol.
已发布 PubMed:体内-体外相关性(ivivc)对调节机构的作用。 The role of in vitro-in vivo correlations (IVIVC) to regulatory agencies.
已发布 PubMed:快速筛选对乙酰氨基酚片 Rapid screening of marketed paracetamol tablets: 使用薄层色谱法和半定量斑点测试。 use of thin-layer chromatography and a semiquantitative spot test.
已发布 PubMed:志愿者食用豆瓣菜后对乙酰氨基酚血浆和尿液氧化代谢产物的减少 Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers.
已发布 PubMed:吃酸面包后延迟胃排空率降低血糖的潜在机制 Delayed gastric emptying rate as a potential mechanism for lowered glycemia after eating sourdough bread: 使用添加了有机酸或有机盐的测试产品进行的 类和大鼠研究。 studies in humans and rats using test products with added organic acids or an organic salt.
已发布 PubMed:二烯丙基硫对对乙酰氨基酚诱导的毒性的保护作用。 Protective effects of diallyl sulfide on acetaminophen-induced toxicities.
已发布 PubMed:破坏力对 体多种单位控释剂型中药物释放的影响 Effect of destruction force on drug release from multiple unit controlled release dosage forms in humans.
已发布 PubMed:乙酰水杨酸止痛药联合用药的慢性口服毒性研究 Studies on the chronic oral toxicity of an analgesic drug combination consisting of acetylsalicylic acid, 大鼠对乙酰氨基酚和咖啡因,包括肾脏的电子显微镜评估。 paracetamol and caffeine in rats including an electron microscopical evaluation of kidneys.
已发布 PubMed:外源生物代谢的表型变异和不利的环境反应 Phenotypic variation in xenobiotic metabolism and adverse environmental response: 专注于硫依赖的排毒途径。 focus on sulfur-dependent detoxification pathways.
已发布 PubMed:对乙酰氨基酚和同位素研究胰腺糖尿病(慢性胰腺炎)患者的胃排空。 Study of gastric emptying in patients with pancreatic diabetes (chronic pancreatitis) using acetaminophen and isotope.
已发布 PubMed:饮食和营养状况对药物代谢的影响。 Influence of diet and nutritional status on drug metabolism.
已发布 PubMed:胃排空清淡的医院早餐。使用实时超声检查的一项研究。 Gastric emptying of a light hospital breakfast. A study using real time ultrasonography.
已发布 PubMed:丁香酚的短期饮食对 的影响。 Effect of short-term dietary administration of eugenol in humans.
已发布 PubMed:毒性测试的比较方法。 1995年5月举行的国际生命科学研究所-ilsi欧洲研讨会之后的共识文件。 Comparative methods of toxicity testing. Consensus document following an International Life Sciences Institute-ILSI Europe Workshop held in May 1995.
已发布 PubMed: 类接触天然存在的氢醌。 Human exposure to naturally occurring hydroquinone.
已发布 PubMed: 药物中蔗糖对牙菌斑酸碱度 pH的影响
已发布 PubMed:热氧化脂质和对乙酰氨基酚同时消耗乙醇作为肝硬化诱导剂的Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis.
已发布 PubMed:口服固体控释剂型 Oral solid controlled release dosage forms: 在禁食和进食条件下, 为破坏力和结肠释放的作用 role of GI-mechanical destructive forces and colonic release in drug absorption under fasted and fed conditions in humans.
已发布 PubMed:结肠手术平衡镇痛后的恢复期和住院时间 Convalescence and hospital stay after colonic surgery with balanced analgesia, 早期口服喂养 early oral feeding, 和强制动员。 and enforced mobilisation.
已发布 PubMed:正常 半固体食物的胃排空,特别要参考血浆对乙酰氨基酚浓度与胃排空时间之间的关系。 [Gastric emptying of semi-solid meal in normal man with special reference to relationship between plasma acetoaminophen concentrations and gastric emptying time].
已发布 PubMed: 切除术和腺样体切除术后的前十二 内饮食对恢复的影响。 The effect of post-operative diet on recovery in the first twelve hours after tonsillectomy and adenoidectomy.
已发布 PubMed:迁移的运动复合物调节肠道运动反应和热量餐的胃排空速度。 The migrating motor complex modulates intestinal motility response and rate of gastric emptying of caloric meals.
已发布 PubMed:对乙酰氨基酚的毒性可通过小鼠的β-胡萝卜素大大降低。 Acetaminophen toxicity is substantially reduced by beta-carotene in mice.
已发布 PubMed:脂肪饮食对雪貂肝脏微粒体氧合的影响 Effect of high fat diet on liver microsomal oxygenations in ferret.
已发布 PubMed:em523l静脉注射对糖尿病胃轻瘫患者餐后胃排空和血浆葡萄糖水平的影响 Effect of intravenous administration of EM523L on gastric emptying and plasma glucose levels after a meal in patients with diabetic gastroparesis: 初步研究。 a pilot study.
已发布 PubMed:长期自愿锻炼可能会改变大鼠内源性和外源性化学物质对肝胆的清除率。 Chronic voluntary exercise may alter hepatobiliary clearance of endogenous and exogenous chemicals in rats.
已发布 PubMed:醇和止痛药-混合非凡。 Alcohol and analgesics--mix extraordinaire.
已发布 PubMed:通过非处方药形成亚硝胺? Nitrosamine formation via non-prescription drugs?
已发布 PubMed:正乙酰半胱氨酸刺激大鼠肝糖原的沉积。 N-acetylcysteine stimulates hepatic glycogen deposition in the rat.
已发布 PubMed:硬膜外吗啡和硬膜外布比卡因对禁食期和进食后胃十二指肠蠕动的影响。 Effects of epidural morphine and epidural bupivacaine on gastroduodenal motility during the fasted state and after food intake.
已发布 PubMed:罗昔康-β-环糊精的评价 Evaluation of piroxicam-beta-cyclodextrin, 吡罗昔康 piroxicam, 对乙酰氨基酚和安慰剂在术后口腔手术中疼痛。 paracetamol and placebo in post-operative oral surgery pain.
已发布 PubMed:[通过非处方药形成亚硝胺?]。 [Nitrosamine formation via non-prescription drugs?].
已发布 PubMed:-柠檬烯对小鼠肝微粒体单加氧酶活性和对乙酰氨基酚诱导的谷胱甘肽耗竭的影响。 Effects of D-limonene on hepatic microsomal monooxygenase activity and paracetamol-induced glutathione depletion in mouse.
已发布 PubMed:蝇幼虫的药物分析。 Drug analysis in fly larvae.
已发布 PubMed:在跑步机上进行的fischer-344雄性大鼠中增加了肾脏药物的代谢。 Increased renal drug metabolism in treadmill-exercised Fischer-344 male rats.
已发布 PubMed:非溃疡性消化不良的胃功能和幽门螺杆菌患病率调查 [Investigation of gastric function and prevalence of Helicobacter pylori in non-ulcer dyspepsia].
已发布 PubMed:术后指示对 切除和腺样体切除术后恢复的影响。 The effect of post-operative instructions on recovery after tonsillectomy and adenoidectomy.
已发布 PubMed:fia安培生物传感器系统对葡萄糖的选择性的改进。 Improvement of the selectivity of an FIA amperometric biosensor system for glucose.
已发布 PubMed:据称扑热息痛和绿s具有体内遗传毒性。 Alleged in vivo genotoxicity of paracetamol and green S.
已发布 PubMed:喂食蛋氨酸限制饮食的小鼠长时间对乙酰氨基酚摄入不会影响铁诱导的肝脂质过氧化或s-腺苷蛋氨酸。 Prolonged acetaminophen ingestion by mice fed a methionine-limited diet does not affect iron-induced liver lipid peroxidation or S-adenosylmethionine.
已发布 PubMed:不同类型早餐对一个种族成员对乙酰氨基酚吸收的影响。 The influence of different types of breakfast on the absorption of paracetamol among members of an ethnic group.
已发布 PubMed:反复摄入低剂量的扑热息痛引起肝毒性。 Hepatotoxicity due to repeated intake of low doses of paracetamol.
已发布 PubMed:乙二胺四乙酸稳定药物化合物中的酰胺和其他基团。 Stabilization by ethylenediaminetetraacetic acid of amide and other groups in drug compounds.
已发布 PubMed:对乙酰氨基酚与细胞核酸共价结合是源自hl-60细胞系的嗜中性粒细胞呼吸爆发的结果。 The covalent binding of acetaminophen to cellular nucleic acids as the result of the respiratory burst of neutrophils derived from the HL-60 cell line.
已发布 PubMed:用对乙酰氨基酚和吲哚菁绿测定狗的小肠通过时间 [Measurement of small bowel transit time in dogs with acetaminophen and indocyanine green].
已发布 PubMed:食物对双氯芬酸纯物质吸收的影响。 The influence of food on the absorption of diclofenac as a pure substance.
已发布 PubMed:通过对乙酰氨基酚试验评估患有和没有自主橙花病变的糖尿病患者的胃液和固体胃排空。 Gastric emptying of liquids and solids evaluated by acetaminophen test in diabetic patients with and without autonomic neuropathy.
已发布 PubMed:膳食中蛋白质对健康志愿者左旋多巴药代动力学的影响。 The influence of protein containing meals on the pharmacokinetics of levodopa in healthy volunteers.
已发布 PubMed:n-乙酰半胱氨酸临床药代动力学。 Clinical pharmacokinetics of N-acetylcysteine.
已发布 PubMed:长期服用对乙酰氨基酚对饮食蛋白质营养利用的影响。 Effects of long-term administration of acetaminophen on the nutritional utilization of dietary protein.
已发布 PubMed:抗氧化剂食品防腐剂加剧了慢性荨麻疹 Chronic urticaria exacerbated by the antioxidant food preservatives, 丁基化羟基茴香醚(bha)和丁基化羟基甲苯(bht)。 butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).
已发布 PubMed:用对乙酰氨基酚和水杨基偶氮磺胺吡啶作为标志物评估膳食对比格犬混悬液胃排空和小肠运输时间的影响。 Effects of meals on gastric emptying and small intestinal transit times of a suspension in the beagle dog assessed using acetaminophen and salicylazosulfapyridine as markers.
已发布 PubMed:可溶性和不溶性纤维补充对餐后葡萄糖耐量的影响 The effect of soluble- and insoluble-fibre supplementation on post-prandial glucose tolerance, 健康受试者中胰岛素和胃抑制多肽的分泌。 insulin and gastric inhibitory polypeptide secretion in healthy subjects.
已发布 PubMed:烟熏食品中亚硝酚和衍生物的遗传毒性的结构基础。 Structural basis of the genotoxicity of nitrosatable phenols and derivatives present in smoked food products.
已发布 PubMed:营养毒理学 Nutritional toxicology: 基本原理和实际问题。 basic principles and actual problems.
已发布 PubMed:不同配方饮食和不同药物制剂对扑热息痛全身可用率的影响 The influence of different formula diets and different pharmaceutical formulations on the systemic availability of paracetamol, 胆囊大小 gallbladder size, 和血浆葡萄糖。 and plasma glucose.
已发布 PubMed:抗氧化剂丁基化羟基茴香醚的亚急性口服摄入对 的临床参数以及i和-ii期生物转化能力的影响。 Effect of subacute oral intake of the food antioxidant butylated hydroxyanisole on clinical parameters and phase-I and -II biotransformation capacity in man.
已发布 PubMed:小鼠对乙酰氨基酚的长期摄入 Prolonged acetaminophen ingestion in mice: 影响蛋氨酸代谢功能 effects on the availability of methionine for metabolic functions.
已发布 PubMed:对乙酰氨基酚和相关芳基胺底物的代谢活化以及核酸结合通过 类粒细胞的呼吸爆发而实现。 Metabolic activation and nucleic acid binding of acetaminophen and related arylamine substrates by the respiratory burst of human granulocytes.
已发布 PubMed:在进食状态下摄入葡萄糖负荷后, 体肝糖原形成的途径。 Pathways of hepatic glycogen formation in humans following ingestion of a glucose load in the fed state.
已发布 PubMed:叙利亚仓鼠的实验性肾乳头坏死。 Experimental renal papillary necrosis in the Syrian hamster.
已发布 PubMed:摄入独家蔗糖饮食对大鼠对乙酰氨基酚肝毒性的影响。 Effect of the intake of an exclusive sucrose diet on acetaminophen hepatotoxicity in rats.
已发布 PubMed:药物制剂的胃排空率。一世。剂型大小的影响 Gastric emptying rates of drug preparations. I. Effects of size of dosage forms, 食物和种类对胃排空率的影响。 food and species on gastric emptying rates.
已发布 PubMed:对乙酰氨基酚长期摄入和饮食蛋氨酸对小鼠肝脏谷胱甘肽的影响。 Effects of prolonged acetaminophen ingestion and dietary methionine on mouse liver glutathione.
已发布 PubMed:对乙酰氨基酚增强镉的肾毒性。 Potentiation of cadmium nephrotoxicity by acetaminophen.
已发布 PubMed:[时间药理学的基本机制]。 [Basic mechanisms of chronopharmacology].
已发布 PubMed:状态对丙硫氧嘧啶诱导的大鼠对乙酰氨基酚肝毒性的保护作用。 Effect of nutritional status on propylthiouracil-induced protection against acetaminophen hepatotoxicity in the rat.
已发布 PubMed:在肥胖的 类中重现对乙酰氨基酚倾向的大鼠模型。 An overfed rat model that reproduces acetaminophen disposition in obese humans.
已发布 PubMed:新鲜分离的肝细胞作为研究扑热息痛毒性的模型。 Freshly isolated hepatocytes as a model for studying the toxicity of paracetamol.
已发布 PubMed:小鼠食物不足后下丘脑的脱氧葡萄糖放射自显影。 Deoxyglucose-autoradiography of the hypothalamus after food deprivation in the mouse.
已发布 PubMed:鼠肾皮质细胞原代培养系统的开发,以评估异种生物的肾毒性。 Development of a primary culture system of rat kidney cortical cells to evaluate the nephrotoxicity of xenobiotics.
已发布 PubMed:氯唑沙宗的肝毒性反应。对21个已识别或推测的病例进行分析。 Chlorzoxazone hepatotoxic reactions. An analysis of 21 identified or presumed cases.
已发布 PubMed:氰化的酪醇 Cyanide-tainted tylenol: 药剂师可以学到什么。 what pharmacists can learn.
已发布 PubMed:长期摄入适量乙醇对雄性大鼠肝微粒体药物代谢活性影响的研究。 Studies on the effect of chronic consumption of moderate amounts of ethanol on male rat hepatic microsomal drug-metabolizing activity.
已发布 PubMed:纳曲酮与 类饮食行为 Naltrexone and human eating behavior: 中度肥胖男性的剂量范围住院试验。 a dose-ranging inpatient trial in moderately obese men.
已发布 PubMed:长期饮酒对男性叙利亚仓鼠肝的影响 Effects of chronic ethanol consumption on male Syrian hamster hepatic, 微粒体混合功能氧化酶。 microsomal mixed-function oxidases.
已发布 PubMed:哮喘的诱发因素。阿司匹林 Precipitating factors in asthma. Aspirin, 亚sulfites, 以及其他药物和化学药品。 and other drugs and chemicals.
已发布 PubMed:和有机化合物对肝谷胱甘肽的影响 Effects of metals and organic compounds on hepatic glutathione, 半胱氨酸 cysteine, acid鱼(mug ugil 头颅 cephalus l。)中的酸和可溶性氨基酸水平。
已发布 PubMed:生物活化和结合的残基。 Bioactivation and bound residues.
已发布 PubMed:健康志愿者口服或直肠给药后对乙酰氨基酚的精华/精粹/精萃生物利用度。 Absolute bioavailability of paracetamol after oral or rectal administration in healthy volunteers.
已发布 PubMed:对乙酰氨基酚致死率中昼夜节律的影响因素。 Factors influencing circadian rhythms in acetaminophen lethality.
已发布 PubMed:食物和药物的相互作用。 Food and drug interactions.
已发布 PubMed:镇痛药与其他药物的相互作用。 Interactions of analgesics with other drugs.
已发布 PubMed:日粮丁基化羟基茴香醚对化学诱导的小鼠急性肝损伤的保护作用。 Protective role of dietary butylated hydroxyanisole against chemical-induced acute liver damage in mice.
已发布 PubMed:萘丁美酮-一种新型抗炎药 Nabumetone--a novel anti-inflammatory drug: 食物的影响 the influence of food, 牛奶 milk, 抗酸药 antacids, 和单剂口服生物利用度的止痛药。 and analgesics on bioavailability of single oral doses.
已发布 PubMed:核黄素状态对大鼠对乙酰氨基酚毒性的影响。 Effect of riboflavin status on acetaminophen toxicity in the rat.
已发布 PubMed:食物对年轻和老年受试者对乙酰氨基酚吸收的影响。 Effect of food on acetaminophen absorption in young and elderly subjects.
已发布 PubMed:扑热息痛的临床药代动力学。 Clinical pharmacokinetics of paracetamol.
已发布 PubMed:急性乙醇给药后,改变了对进食和食物匮乏大鼠的对乙酰氨基酚的处置。 Altered acetaminophen disposition in fed and food-deprived rats after acute ethanol administration.
已发布 PubMed:与对乙酰氨基酚和阿司匹林的药物相互作用的治疗意义。 Therapeutic implications of drug interactions with acetaminophen and aspirin.
已发布 PubMed:体内谷胱甘肽合成的调节 In vivo regulation of hepatic glutathione synthesis: 亲电子化合物对食物缺乏或谷胱甘肽耗竭的影响。 effects of food deprivation or glutathione depletion by electrophilic compounds.
已发布 PubMed:营养和诱导剂对 和动物毒性机制的影响。 The influence of nutrition and inducers on mechanisms of toxicity in humans and animals.
已发布 PubMed:前列腺素前体的厌食活性。 Anorectic activity of prostaglandin precursors.
已发布 PubMed:亲脂酸和相关化合物对细菌和哺乳动物细胞的抑制作用。 Inhibitory effects of lipophilic acids and related compounds on bacteria and mammalian cells.
已发布 PubMed:胃肠道吸收药物。 Gastrointestinal absorption of drugs.
已发布 PubMed:Proceedings: 食品防腐剂对大肠杆菌酸碱度 pH稳态的影响。
已发布 PubMed:解除镇痛性肾病。 Unravelling analgesic nephropathy.
已发布 PubMed:非那西丁的一般和肾脏毒性 General and renal toxicity of phenacetin, 对乙酰氨基酚和一些抗有丝分裂剂在大鼠中。 paracetamol and some anti-mitotic agents in the rat.
 
笔记 Notes:
乙酰苯胺的止痛解热衍生物。它具有较弱的抗炎特性,可以用作常用的镇痛药 Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, 但可能导致肝脏 but may cause liver, 血细胞 blood cell, and 肾 kidney 损伤 damage. analgesic 解热的 antipyretic 衍生物 derivative of 乙酰苯胺 acetanilide. it 已 has 弱 weak 消炎 反 anti-发炎的 inflammatory 属性 properties and is 用过的 used as a 共同 common analgesic, 但可能导致肝脏 but may cause liver, 血细胞 blood cell, 花生油katchung油香豌豆esquirolii油花生油主厨花生油(天然)精制花生油n.f.花生油精制;花生油精制; n.f.花生油美国从一种或多种栽培品种的种子仁中获得的有机精制不挥发性油 and kidney damage. The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, 但严格的分析表明,大多数因治疗剂量而具有所谓毒性的患者都服用了过量药物。重要的 but critical analysis indicates that most patients with alleged toxicity from therapeutic doses have taken overdoses. Importantly, r 22-吞食有害r 24-皮肤接触会中毒r 26-吸入会剧毒。s 01/02-锁紧并放在儿童够不到的地方。s 20/21-使用时请勿进食 prospective studies indicate that therapeutic doses of paracetamol are an unlikely cause of hepatotoxicity in patients who ingest moderate to large amounts of alcohol. (PMID 15733027) 单剂量对乙酰氨基酚是有效的镇痛剂,可用于急性术后疼痛,并且几乎没有副作用。 (mid 14974073) Single doses of paracetamol are effective analgesics for acute postoperative pain and give rise to few adverse effects. (PMID 14974073) 对乙酰氨基酚(aap)过量和由此产生的肝毒性是重要的临床问题。此外 Acetaminophen (AAP) overdose and the resulting hepatotoxicity is an important clinical problem. In addition, aap被广泛用作肝毒素的原型,用于研究化学诱导的细胞损伤的机制并测试新药和草药的保肝潜力。因为它的重要性 AAP is widely used as a prototype hepatotoxin to study mechanisms of chemical-induced cell injury and to test the hepatoprotective potential of new drugs and herbal medicines. Because of its importance, ap引起的肝细胞损伤的机制已被广泛研究和有争议的讨论了很多年。 (pmid 16863451)[hmdb] the mechanisms of AAP-induced liver cell injury have been extensively investigated and controversially discussed for many years. (PMID 16863451) [HMDB]
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