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类别 Category:cosmetic agents
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 熔点 Melting Point: | 134.00 °C. @ 760.00 mm 汞 Hg
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| 沸点 Boiling Point: | 591.66 °C. @ 760.00 mm 汞 Hg (est)
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| 闪点 Flash Point: | 593.00 °F. tcc TCC ( 311.60 °C. ) (est)
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| logp（o / w） logP (o/w): | 0.080 |
| 溶于 Soluble in: |
| | 水 water, 254.5°C下564.5 mg / l（est） 564.5 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
| 首选SDS Preferred SDS: 视图 View |
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
腹腔内小鼠 intra腹膜的 peritoneal-mouse LD50 44 mg/kg
VM/囊 SAC, 兽医和小动物临床医生。卷72 Veterinary Medicine and Small Animal Clinician. Vol. 72, pg. 1330 Pg. 1330, 1977.
静脉老鼠 intra静脉的 venous-mouse LD50 24 mg/kg
Journal of 临床 Clinical 牙周病学 Periodontology. 卷 Vol. 4(5), pg。 66 Pg. 66, 1977.
老鼠 oral-mouse LD50 2515 mg/kg
肺 LUNGS, 胸部 THORAX, 或呼吸 OR RESPIRATION: 急性 ACUTE 肺的 PULMONARY EDEMA
International Congress and 座谈会 Symposium 系列 Series - 皇家的 Royal 社会 Society of 药物 中 Medicine 服务 服务 Services 有限 Limited. 卷 Vol. 23, pg。 45 Pg. 45, 1980.
静脉兔子 intra静脉的 venous-rabbit LD > 8 mg/kg
VM/囊 SAC, 兽医和小动物临床医生。卷72 Veterinary Medicine and Small Animal Clinician. Vol. 72, pg. 1330 Pg. 1330, 1977.
腹膜内大鼠 intra腹膜的 peritoneal-rat LD50 60 mg/kg
VM/囊 SAC, 兽医和小动物临床医生。卷72 Veterinary Medicine and Small Animal Clinician. Vol. 72, pg. 1330 Pg. 1330, 1977.
静脉内大鼠 intra静脉的 venous-rat LD50 21 mg/kg
行为的 BEHAVIORAL: 抽搐 CONVULSIONS OR 影响 EFFECT ON 发作 SEIZURE THRESHOLD
International Congress and 座谈会 Symposium 系列 Series - 皇家的 Royal 社会 Society of 药物 中 Medicine 服务 服务 Services 有限 Limited. 卷 Vol. 23, pg。 45 Pg. 45, 1980.
口鼠 oral-rat LD50 9200 ul uL/kg
GASTROin INTESTin INAL: 胃溃疡或出血 ULCERATION OR BLEEDING FROM STOMACH
肺 LUNGS, 胸部 THORAX, 或呼吸 OR RESPIRATION: 其他变化 OTHER CHANGES
行为的 BEHAVIORAL: ATAXIA
Yakuri to chiryo Chiryo. 药理 Pharmacology and 疗法 Therapeutics. 卷 Vol. 6, pg. 2599 Pg. 2599, 1978.
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| 皮肤毒性 Dermal Toxicity: |
皮下老鼠 subcutaneous-mouse LD50 632 mg/kg
Journal of 临床 Clinical 牙周病学 Periodontology. 卷 Vol. 4(5), pg。 66 Pg. 66, 1977.
皮下大鼠 subcutaneous-rat LD50 > 1000 mg/kg
GASTROin INTESTin INAL: 变化 CHANGES in IN 结构体 STRUCTURE OR 功能 FUNCTION OF 唾液 SALIVARY GLANDS
Journal of 临床 Clinical 牙周病学 Periodontology. 卷 Vol. 4(5), pg。 66 Pg. 66, 1977.
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| 吸入毒性 Inhalation Toxicity: |
|
未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | | cosmetic agents |
| 氯己定用量推荐 Recommendation for chlorhexidine usage levels up to: | | | 不用于香水。 not for fragrance use.
|
| |
| 氯己定香精使用量的推荐标准 Recommendation for chlorhexidine flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
|
安全参考 Safety references:
| Epi系统 EPI System: 视图 View |
| 临床 Clinicaltrials.gov :search |
| 每日医学 Daily Med:search |
| nlm NLM有害物质数据库 :搜索 Search |
| 化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search |
| 辅助引文 AIDS Citations:搜索 Search |
| 癌症引文 Cancer Citations:搜索 Search |
| 毒理学引文 Toxicology Citations:搜索 Search |
| 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search |
| EPA ACToR:毒理学资料 Toxicology Data |
| EPA物质注册服务（SRS） :注册表 Registry |
| 实验室化学安全摘要 Laboratory Chemical Safety Summary :9552079 |
| 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data |
| 德国wgk WGK Germany:3 |
| （1e）-2- [6-[[氨基-[（e）-[氨基-（4-氯苯胺基）亚甲基]氨基]亚甲基]氨基]己基] -1- [氨基-（4-氯苯胺基）亚甲基]胍 (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine |
| chemidplus Chemidplus:0000055561 |
| 技术 RTECS:适用于CAS＃55-56-1的du1925000 DU1925000 for cas# 55-56-1 |
参考资料 References:
| | （1e）-2- [6-[[氨基-[（e）-[氨基-（4-氯苯胺基）亚甲基]氨基]亚甲基]氨基]己基] -1- [氨基-（4-氯苯胺基）亚甲基]胍 (1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| pubchem（cid） Pubchem (cid): | 9552079 |
| pubchem（sid） Pubchem (sid): | 134972280 |
其他资料 Other Information:
| （iupac） (IUPAC): | 元素的原子量2009 Atomic Weights of the Elements 2009 |
| （iupac） (IUPAC): | 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) |
| 影片 Videos: | 元素周期表 The Periodic Table of Videos |
| RBC : | 本网站使用的原子量 Atomic Weights use for this web site |
| （iupac） (IUPAC): | 元素周期表 Periodic Table of the Elements |
| CHEBI: | 视图 View |
| CHEMBL: | 视图 View |
| KEGG (GenomeNet): | C06902 |
| hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): | HMDB15016 |
| 出口关税代码 Export Tariff Code: | 2925.20.4000 |
| 雾度图 Haz-Map: | 视图 View |
| 医药线 MedlinePlusSupp: | 视图 View |
| 化学蜘蛛 ChemSpider: | 视图 View |
| 维基百科 Wikipedia: | 视图 View |
| rsc学习化学 RSC Learn Chemistry: | 视图 View |
配方/制剂 Formulations/Preparations:
＆bull; 0.12％口服溶液 •0.12% oral solution: 雷德克斯（Zila） peridex (zila), 培高乐（高露洁口服药物） periogard (colgate oral pharmaceuticals)
＆bull; 颗粒 pellet延长释放； 2.5毫克芯片 perio芯片 chip（dexcel dexcel 药房 pharma）
各种洗必泰盐和制剂的商品名称 •trade names for various chlorhexidine salts and formulations: chlorhexidine: 灭菌 sterilon, bit烷 hibitane, rotept盐酸洗必泰 rotersept; chlorhexidine dihydrochloride: lisium, 阿拉西德 arlacide h, ay-5312;双醋酸洗必泰 ay-5312; chlorhexidine diacetate: 双乙酸烷 hibitane diacetate, 酚醛清漆氯己定二葡萄糖酸酯 novalsan; chlorhexidine digluconate: 算盘 abacil, 防斑块 anti plaque, 芳酰胺 arlacide g, 掠夺者 bacticlens, 六六氯 chlorhexamed, 二甲苯基 disteryl, Orahexal orahexal, 隔壁的 septeal, 未隔离 unisept, 可可碱 corsodyl, 双足类 hibiclens, 比地尔 hibidil, 芙蓉 hibi擦洗 scrub , bit烷 hibitane, 拉里林 larylin, 氨纶 peridex, 摆出 plac out, 普鲁西德 plurexid, 腐烂的 rotersept, 萨瓦科尔 savacol, 溶剂油 solvahex。
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潜在搅拌机 Potential Blenders and 核心组件 core components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | 生物擦洗 bio擦洗 scrub | | | chlorhexidine, 自由 free base | | 1,6-bis[N'-(p- | chlorophenyl)-N5-biguanido]hexane | | {[(4- | chlorophenyl)氨基 amino]亚氨基甲基} { 亚氨基甲基 亚甲基 iminomethyl}{[(6-{[({[(4-chlorophenyl)氨基 amino]亚甲基 iminomethy l}氨基 l}氨基 amino)亚氨基甲基 亚甲基 iminomethyl]氨基}己基 氨基 amino}hexyl)氨基 amino]亚氨基甲基 亚甲基 iminomethyl}amine | | {[(4- | chlorophenyl)氨基 amino]亚氨基甲基} { 亚氨基甲基 亚甲基 iminomethyl}{[(6-{[({[(4-chlorophenyl)氨基 amino]亚氨基甲基}氨基 亚氨基甲基 亚甲基 iminomethyl}氨基 l}氨基 amino)亚氨基甲基 亚甲基 iminomethyl]氨基}己基 氨基 amino}hexyl)氨基 amino]亚氨基甲基 亚甲基 iminomethyl}amine | | 1,6-bis(5-(p- | chlorophenyl)biguandino biguandino)hexane | | 1,6-bis(5-(p- | chlorophenyl)比瓜尼迪诺 biguanidino)hexane | | 1,6-bis(p- | chlorophenyldiguanido)hexane | | 1,6- | di(4'-氯苯基二胍 -chlorophenyldiguanido)hexane | | 1,6- | di(正对氯苯基二胍 n- N-对氯苯基二胍 p-氯苯基二胍 -chlorophenyldiguanido)hexane | | | exidine | | 1,1'- | hexamethylene bis(5-(对氯p-chlorophenyl)biguanide) | | 1,1'- | hexamethylenebis(5-(对氯p-chlorophenyl)biguanide | | 1,1'- | hexamethylenebis(5-(对氯p-chlorophenyl)biguanide) | | 1,1'- | hexamethylenebis[5-(4-chlorophenyl)biguanide] | | 1,1'- | hexamethylenebis[5-(对氯p-chlorophenyl)biguanide] | | N,N''''- | hexane-1,6-diylbis[N'-(4-chlorophenyl)(亚氨基二碳二亚甲基 imidodicarbonimidic 二酰胺 diamide)] | | N,n''''-1 N''''-1,6- | hexanediylbis[N'-(4-chlorophenyl)(亚氨基二碳二亚甲基 imidodicarbonimidic 二酰胺 diamide)] | | | 喷水 hibispray | | | 亚氨基二碳二亚甲基 imidodicarbonimidic 二酰胺 diamide, N,n''''-1 N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)- | | | 微真皮 microderm | | | 口唇 oro-c镜片 lense | | | 芯片 perio芯片 chip | | | 围裙 periogard | | | 制药 药房 pharmaseal 擦洗 scrub care | | | prevacare prevacare R | | | savloc镜片 lens savloc镜片 lens | | | steri-stat | | 2,4,11,13- | tetraazatetradecanediimidamide, N,n''-双（4-氯苯基）-3 N''-bis(4-chlorophenyl)-3,12-diimino- 12-diimino- |
文章 Articles:
| 已发布 PubMed:不同的含纳米颗粒漱口水对牙釉质的染色效果。 The staining effect of different mouthwashes containing nanoparticles on dental enamel. |
| 已发布 PubMed:通过引入定制包装，减少长期通气的呼吸机相关性肺炎的干预措施。 Intervention to Reduce Ventilator-Associated Pneumonia in Individuals on Long-Term Ventilation by Introducing a Customized Bundle. |
| 已发布 PubMed:霉菌分离物对杀菌剂的敏感性评估。 Assessment of susceptibility of mould isolates towards biocides. |
| 已发布 PubMed:老年 的根龋。 Root Caries in Older Adults. |
| 已发布 PubMed:使用微纤化纤维素的抗菌纸板包装。 Antibacterial paperboard packaging using microfibrillated cellulose. |
| 已发布 PubMed: 嗜温和精神营养性假单胞菌spp spp中抗生素和杀菌剂抗性之间的相关性。在整个肉链生产过程中与屠宰场隔离。 |
| 已发布 PubMed:兽医实践中的消毒剂选择 Disinfectant choices in veterinary practices, 庇护所和家庭 shelters and households: abcd有关猫科环境安全有效消毒的指南。 ABCD guidelines on safe and effective disinfection for feline environments. |
| 已发布 PubMed:肠球菌球菌生物膜对2％洗必泰实质性影响的评估 Evaluation of the Effect of Enterococcus faecalis Biofilm on the 2% Chlorhexidine Substantivity: 体外研究。 An In Vitro Study. |
| 已发布 PubMed:葡萄糖酸洗必太和苯扎氯铵中洋葱伯克霍尔德菌洋葱复合物的存活率和药敏性。 Survival and susceptibility of Burkholderia cepacia complex in chlorhexidine gluconate and benzalkonium chloride. |
| 已发布 PubMed:口疮（复发）。 Aphthous ulcers (recurrent). |
| 已发布 PubMed:在体外和体内抑制新型纳米乳剂对致龋链球菌的变形，抑制生物膜形成并提高抗菌活性。 Inhibited biofilm formation and improved antibacterial activity of a novel nanoemulsion against cariogenic Streptococcus mutans in vitro and in vivo. |
| 已发布 PubMed:杀菌剂苯扎氯铵的效果 Effect of the hand antiseptic agents benzalkonium chloride, 聚维酮碘 povidone-iodine, ethanol, 和葡萄糖酸洗必太对nc / nga小鼠的特应性皮炎。 and chlorhexidine gluconate on atopic dermatitis in NC/Nga mice. |
| 已发布 PubMed:一项随机临床试验比较了在磨牙拔牙后，肺泡内0.2％氯己定生物胶与0.12％氯己定冲洗液对减少牙槽骨炎的效果。 A randomized clinical trial compared the effect of intra-alveolar 0.2 % Chlorohexidine bio-adhesive gel versus 0.12% Chlorohexidine rinse in reducing alveolar osteitis following molar teeth extractions. |
| 已发布 PubMed:醇性手术磨砂膏的比较功效 Comparative efficacy of alcohol-based surgical scrubs: 制定的重要性。 the importance of formulation. |
| 已发布 PubMed:病 分离的qaca / b阳性金黄熊果的特征及医院环境。 Characteristics of qacA/B-positive Staphylococcus aureus isolated from patients and a hospital environment in China. |
| 已发布 PubMed:罗伊氏乳杆菌对致龋菌戈登氏链球菌的抗菌作用 Antimicrobial Effect of Lactobacillus reuteri on Cariogenic Bacteria Streptococcus gordonii, 变形链球菌 Streptococcus mutans, 和牙周疾病升麻和连翘单宁。 and Periodontal Diseases Actinomyces naeslundii and Tannerella forsythia. |
| 已发布 PubMed:前瞻性评估2％（w / v）的乙醇酸葡萄糖酸洗必泰作为献血者手臂制剂的防腐剂。 Prospective evaluation of 2% (w/v) alcoholic chlorhexidine gluconate as an antiseptic agent for blood donor arm preparation. |
| 已发布 PubMed:歐洲海濱草敏感性和对杀生物剂洗必泰的耐受性的比较分析确定了一个复合物的细胞防御网络。 Comparative analysis of Salmonella susceptibility and tolerance to the biocide chlorhexidine identifies a complex cellular defense network. |
| 已发布 PubMed:排泄泵在粪便肠球菌和传统发酵食品中分离的肠球菌球菌的杀菌剂耐受性和抗生素抗性中的作用以及埃达作为粪便抑制剂的作用。 Role of EfrAB efflux pump in biocide tolerance and antibiotic resistance of Enterococcus faecalis and Enterococcus faecium isolated from traditional fermented foods and the effect of EDTA as EfrAB inhibitor. |
| 已发布 PubMed:lia虫链球菌提取物对变形链球菌的评价。 Evaluation of Melia azedarach extracts against Streptococcus mutans. |
| 已发布 PubMed:德尔福酸膜生物膜中洗必泰耐受性的显微和光谱分析。 Microscopic and spectroscopic analyses of chlorhexidine tolerance in Delftia acidovorans biofilms. |
| 已发布 PubMed:在计算机上鉴定来自fda批准药物的靶向野生型和t315i突变abl1的新型激酶抑制剂。 In silico identification of novel kinase inhibitors targeting wild-type and T315I mutant ABL1 from FDA-approved drugs. |
| 已发布 PubMed:抗菌药物卫生产品对志贺菌病风险的定量微生物风险评估。 Quantitative microbial risk assessment of antibacterial hand hygiene products on risk of shigellosis. |
| 已发布 PubMed:Orabase制剂与锦葵属植物乙醇提取物的作用在大鼠口腔伤口愈合中的作用。 Effects of an orabase formulation with ethanolic extract of Malva sylvestris L. in oral wound healing in rats. |
| 已发布 PubMed:在2％葡萄糖酸洗必泰和70％醇中加入食用色素的效果对手术部位具有杀菌作用。 Effects of food colouring added to 2% chlorhexidine gluconate and 70% alcohol for surgical site antisepsis. |
| 已发布 PubMed:食物撞击引起的炎症性植入物周围疾病的非手术治疗 Nonsurgical management of inflammatory periimplant disease caused by food impaction: 临床报告。 a clinical report. |
| 已发布 PubMed:八种血清型的三氯生选择的歐洲海濱草肠突变体的分析表明，氨基糖苷敏感性增加，生长速率降低。 Analysis of triclosan-selected Salmonella enterica mutants of eight serovars revealed increased aminoglycoside susceptibility and reduced growth rates. |
| 已发布 PubMed:小儿反复鼻epi。 Recurrent epistaxis in children. |
| 已发布 PubMed:来自不同来源的肠球菌的杀菌剂和铜耐受性。 Biocide and copper tolerance in enterococci from different sources. |
| 已发布 PubMed:柑桔精油对引起牙周疾病的细菌的协同相互作用和作用方式。 Synergistic interaction and mode of action of Citrus hystrix essential oil against bacteria causing periodontal diseases. |
| 已发布 PubMed:抑制浓度的四种常用杀菌剂对枯草芽孢杆菌中tn916结合转移的影响。 Effect of subinhibitory concentrations of four commonly used biocides on the conjugative transfer of Tn916 in Bacillus subtilis. |
| 已发布 PubMed:杀虫剂洗必太对水生生物的致死和亚致死作用。 Lethal and sub lethal effects of the biocide chlorhexidine on aquatic organisms. |
| 已发布 PubMed:食品防腐剂对14天牙齿生物被膜形成的影响 Action of food preservatives on 14-days dental biofilm formation, 生物膜活力和生物膜来源的牙釉质原位矿化。 biofilm vitality and biofilm-derived enamel demineralisation in situ. |
| 已发布 PubMed:瘦素参与小鼠实验性腹膜纤维化进展的过程。 Involvement of leptin in the progression of experimentally induced peritoneal fibrosis in mice. |
| 已发布 PubMed:消毒液对用于测定咀嚼性能的测试材料的影响。 Influence of disinfectant solutions on test materials used for the determination of masticatory performance. |
| 已发布 PubMed:1979年至1994年和2004年至2010年收集的禽小肠歐洲海濱草分离株对三氯生和其他三种杀生物剂的敏感性比较分析。 Comparative analysis of the susceptibility to triclosan and three other biocides of avian Salmonella enterica isolates collected 1979 through 1994 and 2004 through 2010. |
| 已发布 PubMed:综合二维气相色谱-飞行时间质谱联用技术鉴定针叶林大气气溶胶中的有机物 Combined treatments of enterocin AS-48 with biocides to improve the inactivation of methicillin-sensitive and methicillin-resistant Staphylococcus aureus planktonic and sessile cells. |
| 已发布 PubMed:手术手卫生 Surgical hand hygiene: 擦洗还是擦？ scrub or rub? |
| 已发布 PubMed:评估乳酸菌对杀生物剂的敏感性。 Assessment of the susceptibility of lactic acid bacteria to biocides. |
| 已发布 PubMed:最大限度地减少 感染大肠杆菌o157 Minimizing human infection from Escherichia coli O157:h7使用秋葵。 H7 using GUMBOS. |
| 已发布 PubMed:大肠杆菌o157的消毒剂和抗生素敏感性分析 Disinfectant and antibiotic susceptibility profiles of Escherichia coli O157:来自牛尸体的h7菌株 H7 strains from cattle carcasses, 屎 feces, 以及来自美国的皮革和碎牛肉。 and hides and ground beef from the United States. |
| 已发布 PubMed:空肠弯曲菌和适合于杀菌剂的弯曲杆菌中抗菌素耐药性的发展。 Development of antimicrobial resistance in Campylobacter jejuni and Campylobacter coli adapted to biocides. |
| 已发布 PubMed:在整个肉链生产过程中，对肉类加工厂表面的抗生素和/或杀菌剂具有抗性的细菌的流行。 Prevalence of bacteria resistant to antibiotics and/or biocides on meat processing plant surfaces throughout meat chain production. |
| 已发布 PubMed:使用不同消毒剂的单核细胞增生李斯特菌的比较杀伤力动力学曲线和f值预测模型。 Comparative lethality kinetic curves and predictive models of F-value for Listeria monocytogenes using different sanitizers. |
| 已发布 PubMed:猪耐甲氧西林金黄熊果中存在抗药性基因。 Presence of antiseptic resistance genes in porcine methicillin-resistant Staphylococcus aureus. |
| 已发布 PubMed:泵诱导剂和多药转运蛋白cmeb的遗传变异对空肠弯曲杆菌和大肠杆菌弯曲杆菌抗药性的影响。 Effects of efflux-pump inducers and genetic variation of the multidrug transporter cmeB in biocide resistance of Campylobacter jejuni and Campylobacter coli. |
| 已发布 PubMed:在城市环境中甲基苯丙胺和海洛因使用者的牙科疾病患病率 Dental disease prevalence among methamphetamine and heroin users in an urban setting: 初步研究。 a pilot study. |
| 已发布 PubMed:猪育种设施扬尘中发现的与 和猪有关的高强度耐万古霉素肠球菌。 High-level vancomycin resistant Enterococcus faecium related to humans and pigs found in dust from pig breeding facilities. |
| 已发布 PubMed:花青素对 唾液中离体降解的敏感性。 Susceptibility of anthocyanins to ex vivo degradation in human saliva. |
| 已发布 PubMed:双盲 Double-blinded, 安慰剂对照研究，用于评估过敏性瘙痒狗的止痒洗发水。 placebo-controlled study to evaluate an antipruritic shampoo for dogs with allergic pruritus. |
| 已发布 PubMed:口腔分泌物异常及其临床评价 Inspissated oral secretions and a review of their clinical, 生物 biological, 和生理意义。 and physiological significance. |
| 已发布 PubMed:照料者对于年幼的非洲裔美国儿童进行预防性牙科治疗的可接受性和偏好。 Caregiver acceptability and preferences for preventive dental treatments for young African-American children. |
| 已发布 PubMed:外科准备溶液在腰椎手术中的功效。 Efficacy of surgical preparation solutions in lumbar spine surgery. |
| 已发布 PubMed:现代食品工业中使用杀生物剂控制肠道歐洲海濱草的功效 Efficacy of biocides used in the modern food industry to control salmonella enterica, 以及杀菌剂的耐受性和对临床相关抗菌化合物的耐药性之间的联系。 and links between biocide tolerance and resistance to clinically relevant antimicrobial compounds. |
| 已发布 PubMed:参与o空肠弯曲杆菌和大肠弯曲菌抗微生物剂的外排机制。 Involvement of efflux mechanisms in biocide resistance of Campylobacter jejuni and Campylobacter coli. |
| 已发布 PubMed:拟议的科学模型的专家小组报告，该模型证明了抗菌洗手产品的有效性。 An expert panel report of a proposed scientific model demonstrating the effectiveness of antibacterial handwash products. |
| 已发布 PubMed:氯己定消毒后用于脊髓麻醉的橙花系统并发症。 Neurologic complications after chlorhexidine antisepsis for spinal anesthesia. |
| 已发布 PubMed:非氟化物防龋剂 Nonfluoride caries-preventive agents: 新准则。 new guidelines. |
| 已发布 PubMed:肠毒素as-48联合杀生物剂对浮游和无柄李斯特菌单核细胞增生的影响。 Effect of enterocin AS-48 in combination with biocides on planktonic and sessile Listeria monocytogenes. |
| 已发布 PubMed:摄入量和奶头浸泡方式对奶牛乳中碘浓度的影响 Effects of iodine intake and teat-dipping practices on milk iodine concentrations in dairy cows. |
| 已发布 PubMed:碘在牙科治疗用水的微生物控制中的作用 Effects of iodine in microbial control of dental treatment water. |
| 已发布 PubMed:歐洲海濱草特有油的比较抗菌效果 Comparative antibacterial efficacy of endemic satureja khuzistanica jamzad essential oil, 次氯酸钠和葡萄糖酸洗必太溶液作为根管冲洗液。 sodium hypochlorite and chlorhexidine gluconate solutions as root canal irrigations. |
| 已发布 PubMed:隐形眼镜消毒液的杀菌作用。 Amoebicidal effects of contact lens disinfecting solutions. |
| 已发布 PubMed:对抗菌皂功效的已发表文献的荟萃分析。 A meta-analysis of the published literature on the effectiveness of antimicrobial soaps. |
| 已发布 PubMed:[细菌中抗生素抗性的选择和传播]。 [Selection and spreading of antibiotic resistance in bacteria]. |
| 已发布 PubMed:具有防龋活性的食物成分。 Food components with anticaries activity. |
| 已发布 PubMed:严格的手部卫生和其他习惯可以缩短住院时间，并降低儿科重症监护室的费用和死亡率。 Strict hand hygiene and other practices shortened stays and cut costs and mortality in a pediatric intensive care unit. |
| 已发布 PubMed:食源性肠球菌及其对氧化应激的抵抗力。 Food-borne enterococci and their resistance to oxidative stress. |
| 已发布 PubMed:mrsa定植（消除没有活动/侵入性感染的 的定植）。 MRSA colonisation (eradicating colonisation in people without active/invasive infection). |
| 已发布 PubMed:商业加工厂的火鸡歐洲海濱草肠分离株对抗生素的耐药性 Characterization of Salmonella enterica isolates from turkeys in commercial processing plants for resistance to antibiotics, 消毒剂 disinfectants, 和增长促进剂。 and a growth promoter. |
| 已发布 PubMed:七种洗手液对鼠诺如 的比较功效 Comparative efficacy of seven hand sanitizers against murine norovirus, 猫杯状 feline calicivirus, 和gii.4诺如 。 and GII.4 norovirus. |
| 已发布 PubMed:问我们。白斑病变 Ask us. White spot lesions: 预防和治疗。 prevention and treatment. |
| 已发布 PubMed: 预防成 龋齿的研究设计（吃豆子 PACS） : 一项评估洗必泰牙科涂料预防成 龋齿效果的随机临床试验。 a randomized clinical trial assessing the effect of a chlorhexidine dental coating for the prevention of adult caries. |
| 已发布 PubMed:嗜麦芽窄食单胞菌的临床菌株分离和抗生素敏感性研究。 [Clinical strains isolation and antibiotic susceptibility of Stenotrophomonas maltophilia]. |
| 已发布 PubMed:运动障碍患者使用含1％洗必泰牙膏的临床和微生物学评估以及动机对口腔卫生的影响。 Clinical and microbiological evaluation of the use of toothpaste containing 1% chlorhexidine and the influence of motivation on oral hygiene in patients with motor deficiency. |
| 已发布 PubMed:果蝇翼点试验中两种漱口水产品的遗传毒性。 Genotoxicity of two mouthwash products in the Drosophila Wing-Spot Test. |
| 已发布 PubMed:在3600例儿科泌尿外科手术中，avagard手消毒与传统磨砂进行了比较。 Avagard hand antisepsis vs. traditional scrub in 3600 pediatric urologic procedures. |
| 已发布 PubMed:肠内和肠外营养中的碘。 Iodine in enteral and parenteral nutrition. |
| 已发布 PubMed:3.4岁的11-12岁芬兰小学生进行的一项随机对照临床试验中龋齿控制方案的成本效益。 Cost-effectiveness of an experimental caries-control regimen in a 3.4-yr randomized clinical trial among 11-12-yr-old Finnish schoolchildren. |
| 已发布 PubMed:根龋的临床管理。 Clinical management of root caries. |
| 已发布 PubMed:空肠弯曲菌对鸡皮肤和肉的化学去污。 Chemical decontamination of Campylobacter jejuni on chicken skin and meat. |
| 已发布 PubMed:照料者对西班牙裔儿童早期预防龋齿的可接受性和偏好。 Caregiver acceptability and preferences for early childhood caries preventive treatments for Hispanic children. |
| 已发布 PubMed:牙龈轮廓斑块指数的应用 Application of the gingival contour plaque index: 六个月的牙菌斑和牙龈炎研究。 six-month plaque and gingivitis study. |
| 已发布 PubMed:抗菌漱口水消除了饮食中硝酸盐对胃的保护作用和降低血压的作用。 Gastroprotective and blood pressure lowering effects of dietary nitrate are abolished by an antiseptic mouthwash. |
| 已发布 PubMed:比较三种漱口水溶液降低唾液中变形链球菌水平的功效。 Comparison of the efficacy of three different mouthrinse solutions in decreasing the level of streptococcus mutans in saliva. |
| 已发布 PubMed:牛至精油诱导铜绿假单胞菌和金黄熊果细胞功能和形态变化的研究 Investigation of functional and morphological changes in Pseudomonas aeruginosa and Staphylococcus aureus cells induced by Origanum compactum essential oil. |
| 已发布 PubMed:过敏性接触性皮炎在特应性皮炎中进行局部治疗的普遍性和危险因素 Prevalence and risk factors for allergic contact dermatitis to topical treatment in atopic dermatitis: 一项针对641名儿童的研究。 a study in 641 children. |
| 已发布 PubMed:抗菌染料浸渍的新型抗菌手套在预防多药耐药医院病原体粘附方面的功效。 Efficacy of novel antimicrobial gloves impregnated with antiseptic dyes in preventing the adherence of multidrug-resistant nosocomial pathogens. |
| 已发布 PubMed:灼伤（轻微热）。 Burns (minor thermal). |
| 已发布 PubMed:牙周皮瓣术后洗必泰具有防变色系统 Chlorhexidine with an anti discoloration system after periodontal flap surgery: 交叉 a cross-over, 随机的 randomized, 三盲临床试验。 triple-blind clinical trial. |
| 已发布 PubMed:常用食品防腐剂对变形链球菌体外生物膜形成的影响 Effects of commonly used food preservatives on biofilm formation of Streptococcus mutans in vitro. |
| 已发布 PubMed:食品防腐剂对原位生物膜形成的影响。 Effect of food preservatives on in situ biofilm formation. |
| 已发布 PubMed:术前皮肤准备用抗菌剂的综述。 A review of anti-septic agents for pre-operative skin preparation. |
| 已发布 PubMed:从制药生产单元的洁净室中分离出主要细菌的特征。 Characterization of predominant bacteria isolates from clean rooms in a pharmaceutical production unit. |
| 已发布 PubMed: 从乳制品和冷冻蔬菜中分离出的单核细胞增生李斯特菌菌株对抑制壁素 murein合成的抗生素和消毒剂的敏感性。 |
| 已发布 PubMed:惰性标记物（氧化铬或不溶性灰分（油果、檢果、海胡桃、南洋石栗））的比较，以确定含或不含酶的小麦或大麦类肉鸡日粮的表观代谢能。 Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgery. |
| 已发布 PubMed:口疮（复发）。 Aphthous ulcers (recurrent). |
| 已发布 PubMed:乳香胶甲醇提取物对牙龈卟啉单胞菌的抗菌作用。 Antimicrobial effect of mastic gum methanolic extract against Porphyromonas gingivalis. |
| 已发布 PubMed:天然河流生物膜中洗必泰的定量定位 Quantitative mapping of chlorhexidine in natural river biofilms. |
| 已发布 PubMed:含乙基己基甘油和防腐剂协同作用的醇类手术手消毒剂的体内功效。 In vivo efficacy of an alcohol-based surgical hand disinfectant containing a synergistic combination of ethylhexylglycerin and preservatives. |
| 已发布 PubMed:食入口腔涂料引起的儿童利多卡因和氯己定毒性 Lignocaine and chlorhexidine toxicity in children resulting from mouth paint ingestion: 装瓶问题。 a bottling problem. |
| 已发布 PubMed:评估使用抗菌手工产品的收益 Assessment of benefits from use of antimicrobial hand products: 减少处理碎牛肉的风险。 reduction in risk from handling ground beef. |
| 已发布 PubMed:牙周疗法的影响和抗菌剂对呼吸异味相关结果变量的辅助作用 The impact of periodontal therapy and the adjunctive effect of antiseptics on breath odor-related outcome variables: 一项双盲随机研究。 a double-blind randomized study. |
| 已发布 PubMed:通过牙膏和含有或不含有多肽的嵌段共聚物的溶液预防牙菌斑的重新生长。 The prevention of plaque re-growth by toothpastes and solutions containing block copolymers with and without polypeptide. |
| 已发布 PubMed:独特的水可选卫生保健 员洗手液可提供抗菌持久性和残留效果，同时减少了对其他产品的需求。 A unique water optional health care personnel handwash provides antimicrobial persistence and residual effects while decreasing the need for additional products. |
| 已发布 PubMed:气雾剂处理蝇my丝虫病后绵羊组织中的多杀菌素残留。 Residues of spinosad in the tissues of sheep after aerosol treatment of blowfly myiasis. |
| 已发布 PubMed:使用洗必太/没食子酸正丙酯作为尿液防腐剂。 The use of chlorhexidine/n-propyl gallate as a urine preservative. |
| 已发布 PubMed:从食用动物中分离出来的不同细菌对硫酸铜的敏感性 Susceptibility of different bacterial species isolated from food animals to copper sulphate, 氯化锌和抗菌物质用于消毒。 zinc chloride and antimicrobial substances used for disinfection. |
| 已发布 PubMed:唾液培养试验以评估口腔恶臭 A salivary incubation test for evaluation of oral malodor: 初步研究。 a pilot study. |
| 已发布 PubMed:乳腺内输注后，牛奶中洗必太的消除动力学停止了奶牛乳腺乳腺的泌乳。 Elimination kinetics of chlorhexidine in milk following intramammary infusion to stop lactation in mastitic mammary gland quarters of cows. |
| 已发布 PubMed:木糖醇和龋齿 Xylitol and dental caries: 临床医生概述。 an overview for clinicians. |
| 已发布 PubMed:定量乳原奶中洗必泰残留量的方法 Methodology for quantifying residues of chlorhexidine in raw dairy milk. |
| 已发布 PubMed:和消毒剂对橙花节胞藻孢子囊活力的影响 Effects of high temperature and disinfectants on the viability of Sarcocystis neurona sporocysts. |
| 已发布 PubMed:舌头刷牙和漱口水是口臭的基本治疗方法。 Tongue brushing and mouth rinsing as basic treatment measures for halitosis. |
| 已发布 PubMed:使用文献和实验数据对洗手功效进行风险评估。 Risk assessment of hand washing efficacy using literature and experimental data. |
| 已发布 PubMed:从食品工业中分离出的乳酸菌具有消毒和抗药性。 Disinfectant and antibiotic resistance of lactic acid bacteria isolated from the food industry. |
| 已发布 PubMed:含大豆油的地西epa亚微乳剂，用于口服或直肠给药。 Diazepam submicron emulsions containing soya-bean oil and intended for oral or rectal delivery. |
| 已发布 PubMed:牙膏对洗必太和十六烷基氯化吡啶鎓在体外产生染色的倾向的影响 The effect of toothpaste on the propensity of chlorhexidine and cetyl pyridinium chloride to produce staining in vitro: 灭活的可能预测因子。 a possible predictor of inactivation. |
| 已发布 PubMed:龋病风险评估与预防 Caries risk assessment and prevention: 领先战略 strategies for Head Start, 尽早开始 Early Head Start, 和wic。 and WIC. |
| 已发布 PubMed:闪电加热使火山灰颗粒变圆的尺寸限制。 Site specific delivery of antimicrobial agents for periodontal disease. |
| 已发布 PubMed:1998年获得新药批准。 New drug approvals in 1998. |
| 已发布 PubMed:牙科保健师的新视野 A new horizon for the dental hygienist: 控制抗菌剂的局部递送。 controlled local delivery of antimicrobials. |
| 已发布 PubMed:使用红外热像仪检测牛生长促进剂耳植入物污染引起的炎症。 Use of infrared thermography to detect inflammation caused by contaminated growth promotant ear implants in cattle. |
| 已发布 PubMed:肠炎歐洲海濱草污染的带壳蛋的消毒效果。对鸡蛋测试的影响。 Efficacy of disinfection of shell eggs externally contaminated with Salmonella enteritidis. Implications for egg testing. |
| 已发布 PubMed:防腐剂浸渍的中心静脉导管预防导管相关血流感染的成本效益。 Cost-effectiveness of antiseptic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection. |
| 已发布 PubMed:浮游细菌和附着的枯草芽孢杆菌以及荧光假单胞菌对消毒剂处理的不同反应。 Different responses of planktonic and attached Bacillus subtilis and Pseudomonas fluorescens to sanitizer treatment. |
| 已发布 PubMed:最新的fda牙科认证。 Latest FDA approvals for dentistry. |
| 已发布 PubMed:洗必泰芯片局部递送系统的放置时间和便利性。 The time and ease of placement of the chlorhexidine chip local delivery system. |
| 已发布 PubMed:对屠宰前肉鸡场去污的潜在消毒剂的评估。 Evaluation of potential disinfectants for preslaughter broiler crop decontamination. |
| 已发布 PubMed:漱口后唾液中洗必泰的高效液相色谱分析。 High-performance liquid chromatographic analysis of chlorhexidine in saliva after mouthrinsing. |
| 已发布 PubMed:持久的抗菌特性和无刷应用的新型醇基手术手磨砂配方的开发和评估。 Development and evaluation of a new alcohol-based surgical hand scrub formulation with persistent antimicrobial characteristics and brushless application. |
| 已发布 PubMed:非水毛细管电泳法-在食品分析中的适用性 Nonaqueous capillary electrophoresis--its applicability in the analysis of food, 药品和生物液体。 pharmaceuticals and biological fluids. |
| 已发布 PubMed:亚氯酸术前皮肤消毒的临床疗效。 Clinical efficacy of a chlorous acid preoperative skin antiseptic. |
| 已发布 PubMed:牛肉去污大肠杆菌o157 Decontaminating beef for Escherichia coli O157:h7。 H7. |
| 已发布 PubMed:对氯己定浸渍的医疗设备的潜在超敏反应。 Potential hypersensitivity reactions to chlorhexidine-impregnated medical devices. |
| 已发布 PubMed:预防幼儿龋齿。 Prevention of early childhood caries. |
| 已发布 PubMed:来自食品和药物管理局。 From the Food and Drug Administration. |
| 已发布 PubMed:局部给药在牙周疾病管理中的作用 The role of local drug delivery in the management of periodontal diseases: 全面的审查。 a comprehensive review. |
| 已发布 PubMed:食用富含硝酸盐和胺的食物期间亚硝胺的形成 Formation of nitrosamines during consumption of nitrate- and amine-rich foods, 以及使用漱口水的影响。 and the influence of the use of mouthwashes. |
| 已发布 PubMed:酸化的亚氯酸钠和洗必泰漱口水对牙菌斑再生和唾液细菌计数的比较作用。 The comparative effect of acidified sodium chlorite and chlorhexidine mouthrinses on plaque regrowth and salivary bacterial counts. |
| 已发布 PubMed:不同品牌的茶和咖啡容易引起洗必泰染色的倾向。 The propensity of different brands of tea and coffee to cause staining associated with chlorhexidine. |
| 已发布 PubMed:fda专家组发现数据不足，无法批准抗菌手套。 FDA panel finds insufficient data to approve antimicrobial glove. |
| 已发布 PubMed:梯度液相色谱法测定散装物料中的洗必泰及其降解产物。 Gradient liquid chromatographic method for determination of chlorhexidine and its degradation products in bulk material. |
| 已发布 PubMed:糜烂和溃疡性皮肤病。 Erosive and ulcerative skin disease. |
| 已发布 PubMed:龋齿诊断和风险评估。预防策略和管理的回顾。 Caries diagnosis and risk assessment. A review of preventive strategies and management. |
| 已发布 PubMed:悬浮和表面附着的肠炎歐洲海濱草对杀菌剂和高温的敏感性。 Susceptibility of suspended and surface-attached Salmonella enteritidis to biocides and elevated temperatures. |
| 已发布 PubMed:通过漱口水进行体外饮食染色，作为抗菌活性的比较指标和体内染色的预测因子。 Dietary staining in vitro by mouthrinses as a comparative measure of antiseptic activity and predictor of staining in vivo. |
| 已发布 PubMed: 单核细胞增生性李斯特菌对葡萄糖的吸收和片球菌素 pediocin jd的抑制作用。 |
| 已发布 PubMed:洗必泰二葡萄糖酸盐杂质的鉴定和分离。 Identification and isolation of chlorhexidine digluconate impurities. |
| 已发布 PubMed:五种洗必泰奶嘴浸剂的功效评估。 Efficacy evaluations on five chlorhexidine teat dip formulations. |
| 已发布 PubMed:切除奶牛的57头奶头消毒器的评估。 Evaluation of 57 teat sanitizers using excised cow teats. |
| 已发布 PubMed:通过局部使用含有洗必泰的可降解控释系统抑制比格犬斑块形成和牙龈炎。 Inhibition of plaque formation and gingivitis in beagle dogs by topical use of a degradable controlled-release system containing chlorhexidine. |
| 已发布 PubMed:评估欧洲悬浮液测试方法对消毒剂和防腐剂的抗菌活性的可重复性和可重复性。 Evaluation of the repeatability and reproducibility of European suspension test methods for antimicrobial activity of disinfectants and antiseptics. |
| 已发布 PubMed:[龋齿的个体风险评估]。 [Individual risk assessment of caries]. |
| 已发布 PubMed:生物发光单核细胞增生性李斯特菌提供了一种快速的测定杀生物剂功效的方法。 Bioluminescent Listeria monocytogenes provide a rapid assay for measuring biocide efficacy. |
| 已发布 PubMed:fda和ada如何影响口腔护理处方药的开发。 How the FDA and the ADA affect development of prescription drugs for oral care. |
| 已发布 PubMed: 体口服硝酸盐还原活性与内源性亚硝基氨基酸定量关系。 Quantitative relationship between oral nitrate-reducing activity and the endogenous formation of N-nitrosoamino acids in humans. |
| 已发布 PubMed:影响滴眼液中二氯氯己定液相色谱定量的问题。 Problems affecting the liquid chromatographic quantitation of chlorhexidine digluconate in ophthalmic solutions. |
| 已发布 PubMed:模拟医护 员洗手液中中和剂的重要性。 Importance of neutralizers in the stripping fluid in a simulated healthcare personnel handwash. |
| 已发布 PubMed:自我管理药物中的可发酵单糖，可作为猖car龋齿中的病因。案例报告。 Fermentable simple sugars in self-administered medications as aetiologic agents in rampant caries. Case report. |
| 已发布 PubMed:体内生物发光 In vivo bioluminescence: 从事研究和行业研究的手机记者。 a cellular reporter for research and industry. |
| 已发布 PubMed:[斑块和斑块控制]。 [Plaque and plaque control]. |
| 已发布 PubMed:酸-尿素体系作为b-族维生素的提取介质的评价。第二部分简化谷物产品中烟酸和烟酰胺的半自动化化学分析。 Evaluation of the skin disinfecting activity and cumulative effect of chlorhexidine and triclosan handwash preparations on hands artificially contaminated with Serratia marcescens. |
| 已发布 PubMed:专家讨论杀精剂的发展。 Experts discuss development of spermicides. |
| 已发布 PubMed:[避孕发展-美国的看法在80年代中期]。 [Contraceptive development--the view from the U.S.A. in the mid 80s]. |
| 已发布 PubMed:金属和洗必泰使牙齿外在变色。一世。表面蛋白质变性或饮食沉淀？ Extrinsic tooth discoloration by metals and chlorhexidine. I. Surface protein denaturation or dietary precipitation? |
| 已发布 PubMed:化学牙菌斑控制和外在牙齿变色。审查可能的机制。 Chemical plaque control and extrinsic tooth discoloration. A review of possible mechanisms. |
| 已发布 PubMed:对在白念珠菌生长过程中将洗必泰掺入自聚合丙烯酸树脂板中的影响的体外和体内研究。 An in vitro and in vivo study of the effect of incorporation of chlorhexidine into autopolymerizing acrylic resin plates upon the growth of Candida albicans. |
| 已发布 PubMed:洗必泰抗菌漱口水的体内和体外抗菌性能Comparison of the in vivo and in vitro antibacterial properties of antiseptic mouthrinses containing chlorhexidine, lex啶 alexidine, 十六烷基吡咯氯化二碘和己啶。与行动方式有关。 cetyl pyridinium chloride and hexetidine. Relevance to mode of action. |
| 已发布 PubMed:饮食因素在使用洗必泰相关的牙齿染色病因中作用的体外研究。 An in vitro study of the role of dietary factors in the aetiology of tooth staining associated with the use of chlorhexidine. |
| 已发布 PubMed:[控制洗必泰和亚磺酰胺化合物在致病性熊果鼻腔载体中的作用]。 [Control of the effectiveness of chlorhexidine and a sulfamide compound in nasal carriers of pathogenic Staphylococcus]. |
| 已发布 PubMed:[预防龋齿]。 [Caries prophylaxis]. |
| 已发布 PubMed:染料与洗必泰处理的羟基磷灰石的结合。 Binding of dyes to chlorhexidine-treated hydroxyapatite. |
| 已发布 PubMed:[斑块形成及其预防]。 [Plaque formation and its prevention]. |
| 已发布 PubMed:牙列的内在和外在变色（文献综述）。 Intrinsic and extrinsic discoloration of the dentition (a literature review). |
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3D/INCHI