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类别 Category:cosmetic ingredient for skin conditioning
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 沸点 Boiling Point: | 493.28 °C. @ 760.00 mm 汞 Hg (est)
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| 闪点 Flash Point: | 480.00 °F. tcc TCC ( 248.80 °C. ) (est)
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| logp（o / w） logP (o/w): | 10.542（est） 10.542 (est) |
| 溶于 Soluble in: |
| | 水 water, 9.679e-006 mg / l @ 25°C（est） 9.679e-006 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
| 首选SDS Preferred SDS: 视图 View |
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | cosmetic ingredient for skin conditioning |
| 推荐的胆固醇胆固醇的使用水平不超过 Recommendation for cholesteryl acetate usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 乙酸胆甾醇酯调味剂的使用建议水平最高为 Recommendation for cholesteryl acetate flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | acetic acid cholesteryl ester | | | cholest-5-en-3-beta beta-yl acetate | | (3b)- | cholest-5-en-3-yl acetate | | | cholesterin acetate | | | cholesterol acetate | | | 胆固醇乙酸酯 cholesterylacetate |
文章 Articles:
| 已发布 PubMed:病原体相关酵母蛋白pry1的小窝结合基序 The caveolin-binding motif of the pathogen-related yeast protein Pry1, 帽蛋白超家族的成员 a member of the CAP protein superfamily, 体内输出胆固醇胆固醇是必需的。 is required for in vivo export of cholesteryl acetate. |
| 已发布 PubMed:3β,6α-二乙氧基-5 6α-Diacet-oxy-5,9α-dihy-droxy-5α-cholest-7-en-11-one。 9α-dihy-droxy-5α-cholest-7-en-11-one. |
| 已发布 PubMed:3β,6β-二乙氧基-5 6β-Diacet-oxy-5,9α-二乙氧基-5α-胆甾-7-烯-11-一乙酸0.04溶剂化物。 9α-dihy-droxy-5α-cholest-7-en-11-one acetic acid 0.04-solvate. |
| 已发布 PubMed:病原体相关的酵母（pry）蛋白和cap超家族成员是固醇结合蛋白。 Pathogen-Related Yeast (PRY) proteins and members of the CAP superfamily are secreted sterol-binding proteins. |
| 已发布 PubMed:杆菌霉素d的构象分析 Conformational analyses of bacillomycin D, 天然抗菌脂肽 a natural antimicrobial lipopeptide, 单独或与空气-水界面处的脂质单层相互作用。 alone or in interaction with lipid monolayers at the air-water interface. |
| 已发布 PubMed:膜联蛋白a6与富含胆固醇的膜的相互作用是ph依赖性的，并由固醇介导。 Interaction of annexin A6 with cholesterol rich membranes is pH-dependent and mediated by the sterol OH. |
| 已发布 PubMed:健壮的 A robust, 敏感 sensitive, 核磁共振技术快速阐明结构的多用途hmbc实验 and versatile HMBC experiment for rapid structure elucidation by NMR: Impact-hmbc HMBC。 |
| 已发布 PubMed:通过多频同核去耦（mdec）对小分子中的复合物nmr光谱进行反卷积 Deconvolution of complex NMR spectra in small molecules by multi frequency homonuclear decoupling (MDEC). |
| 已发布 PubMed:预测药物和其他化合物在有机溶剂中的溶解度。 Prediction of solubility of drugs and other compounds in organic solvents. |
| 已发布 PubMed:胆固醇半琥珀酸酯 Cholesterol hemisuccinate: x dna聚合酶家族的选择性抑制剂。 a selective inhibitor of family X DNA polymerases. |
| 已发布 PubMed:类固醇对溶骨素相互作用的结构要求 Steroid structural requirements for interaction of ostreolysin, 脂筏结合细胞溶素 a lipid-raft binding cytolysin, 与脂质单层和双层。 with lipid monolayers and bilayers. |
| 已发布 PubMed:ch3reo3介导的不饱和甾体化合物与h2o2的区域和立体选择性氧化。 Regio and stereoselective oxidations of unsaturated steroidal compounds with H2O2 mediated by CH3ReO3. |
| 已发布 PubMed:通过电喷雾串联质谱法（esi-ms / ms）对胆固醇和胆固醇酯的高通量定量分析。 High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS). |
| 已发布 PubMed:胆固醇及其阴离子衍生物抑制多形核明串球菌和monomac6细胞中的5-脂氧合酶活化。 Cholesterol and its anionic derivatives inhibit 5-lipoxygenase activation in polymorphonuclear leukocytes and MonoMac6 cells. |
| 已发布 PubMed:混合朗缪尔单层中的极性头基相互作用。 Polar head group interactions in mixed Langmuir monolayers. |
| 已发布 PubMed:混合反胶束中的渗透现象 Percolation phenomenon in mixed reverse micelles: 添加剂的作用。 the effect of additives. |
| 已发布 PubMed:胆固醇基链烷酸酯共拉伸模式的理论和振动光谱分析 Theoretical and vibrational spectroscopic analysis of the CO stretching mode of cholesteryl alkanoates: 乙酸胆固醇酯的特殊情况。 the particular case of the cholesteryl acetate. |
| 已发布 PubMed:通过三旋相干选择，在固态13c nmr中进行亚甲基光谱编辑。 Methylene spectral editing in solid-state 13C NMR by three-spin coherence selection. |
| 已发布 PubMed:聚羟基甾醇的合成（v） Synthesis of polyhydroxysterols (V): 高效和立体定向合成24-亚甲基胆甾-5-烯-3β efficient and stereospecific synthesis of 24-methylene-cholest-5-ene-3beta,7α-二醇及其c-7差向异构体。 7alpha-diol and its C-7 epimer. |
| 已发布 PubMed:吡啶甲酸铁络合物诱导的具有双氧的乙酸胆固醇酯的立体选择性烯丙基羟化反应的新型电化学系统 A new electrochemical system for stereoselective allylic hydroxylation of cholesteryl acetate with dioxygen induced by iron picolinate complexes. |
| 已发布 PubMed:β1-42淀粉样肽的体外原纤维形成 In vitro fibrillogenesis of the amyloid beta 1-42 peptide: 胆固醇增强和阿司匹林抑制。 cholesterol potentiation and aspirin inhibition. |
| 已发布 PubMed:铑（ii Rhodium(II,ii）二聚体作为磺酰胺的叠氮和类固醇酰胺化的有效催化剂。 II) dimer as an efficient catalyst for aziridination of sulfonamides and amidation of steroids. |
| 已发布 PubMed:霍乱弧菌溶血素（vcc）与胆固醇的相互作用 Interaction of the Vibrio cholerae cytolysin (VCC) with cholesterol, 一些胆固醇酯 some cholesterol esters, 和胆固醇衍生物 and cholesterol derivatives: 一项临时研究。 a TEM study. |
| 已发布 PubMed:金属卟啉介导的不对称氮原子转移至烃 Metalloporphyrin-mediated asymmetric nitrogen-atom transfer to hydrocarbons: 手性钌和锰卟啉催化烯烃的叠氮化和饱和c-h键的酰胺化 aziridination of alkenes and amidation of saturated C-H bonds catalyzed by chiral ruthenium and manganese porphyrins. |
| 已发布 PubMed: 血浆低密度脂蛋白中血小板活化因子乙酰水解酶和转乙酰酶的活性 Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein. |
| 已发布 PubMed:固醇和鞘脂强烈影响流感 血凝素诱导的融合孔的生长。 Sterols and sphingolipids strongly affect the growth of fusion pores induced by the hemagglutinin of influenza virus. |
| 已发布 PubMed:orsat以及seft和apt的修改。 ORSAT and modifications of SEFT and APT. |
| 已发布 PubMed:同时定量橙花酰胺和1 Simultaneous quantitation of ceramides and 1, 医护 员 iatroscan薄层色谱-火焰电离检测法检测组织中的2-二酰基甘油。 |
| 已发布 PubMed:在富含胆固醇的硫酸大鼠血小板中增强花生四烯酸和钙代谢。 Enhanced arachidonic acid and calcium metabolism in cholesteryl sulfate-enriched rat platelets. |
| 已发布 PubMed:类固醇分子结构对其中断间隙连接通讯能力的影响。 Influence of the molecular structure of steroids on their ability to interrupt gap junctional communication. |
| 已发布 PubMed:胆甾醇硫酸盐对血小板的产生和生物学作用。 Occurrence and biological effects of cholesteryl sulfate on blood platelets. |
| 已发布 PubMed:固醇对含二棕榈酰磷脂酰胆碱单分子层中分子相互作用和侧向结构域形成的影响 Effect of sterol structure on molecular interactions and lateral domain formation in monolayers containing dipalmitoyl phosphatidylcholine. |
| 已发布 PubMed:增强了富含胆固醇的硫酸盐的低密度脂蛋白对铜介导的氧化的敏感性。 Enhanced susceptibility of cholesteryl sulfate-enriched low density lipoproteins to copper-mediated oxidation. |
| 已发布 PubMed:由水包油乳液制备的纳米颗粒的结构。 Structures of nanoparticles prepared from oil-in-water emulsions. |
| 已发布 PubMed:乙酸胆固醇酯的热氧化产物的鉴定。 Identification of thermal oxidation products of cholesteryl acetate. |
| 已发布 PubMed: 骆驼蜱 tick体表上的胆固醇酯 , 透明质酸 Hyalomma dromedarii (Koch, 1844年）和棕色的狗蜱 tick , rhipicephalus sanguineus（latreille , 1806). |
| 已发布 PubMed:用生育酚和胆固醇的半琥珀酸酯预处理大鼠可预防四氯化碳引起的肝毒性。 Protection against carbon tetrachloride-induced hepatotoxicity by pretreating rats with the hemisuccinate esters of tocopherol and cholesterol. |
| 已发布 PubMed:一种通过在水包油乳液中沉淀制备微水溶性药物的亚微米颗粒的方法。 ii A method for the preparation of submicron particles of sparingly water-soluble drugs by precipitation in oil-in-water emulsions. II: 乳化剂的影响 Influence of the emulsifier, 溶剂 the solvent, 和原料药。 and the drug substance. |
| 已发布 PubMed:一种通过在水包油乳液中沉淀制备微水溶性药物的亚微米颗粒的方法。一世 A method for the preparation of submicron particles of sparingly water-soluble drugs by precipitation in oil-in-water emulsions. I: 乳化和表面活性剂浓度的影响。 Influence of emulsification and surfactant concentration. |
| 已发布 PubMed:中子衍射在123和20 k处乙酸胆固醇酯的晶体结构和热振动 Crystal structure and thermal vibrations of cholesteryl acetate from neutron diffraction at 123 and 20 K. |
| 已发布 PubMed:定量测定1 Quantitative determination of 1, 使用医护 员 iatroscan 薄层色谱 TLC / 菲德 FID在大鼠胸主动脉中生成2-二酰基甘油 : 去甲肾上腺素的作用。 effect of norepinephrine. |
| 已发布 PubMed:水诱导胆固醇及其乙酸盐沉淀的热力学 Thermodynamics of water-induced precipitation of cholesterol and its acetate, 溶于1的苯甲酸酯和硬脂酸酯衍生物 benzoate and stearate derivatives dissolved in 1,4-二恶烷和2-丙醇。 4-dioxane and 2-propanol. |
| 已发布 PubMed:色谱分离乙酸胆固醇酯及其氯类似物 Chromatographic separation of cholesteryl acetate and its chloro analogues. |
| 已发布 PubMed:氯乙酸和乙酸与胆固醇的共价相互作用 Covalent interaction of chloroacetic and acetic acids with cholesterol. |
| 已发布 PubMed:定量1 Quantitation of 1, 医护 员 iatroscan 薄层色谱 TLC / 菲德 FID在大鼠心脏中的2-二酰基甘油 |
| 已发布 PubMed:正常和狼 淋巴样细胞系胆固醇酯酶的酰基链特异性和特性。 Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. |
| 已发布 PubMed:大鼠睾丸中多种形式的胆固醇酯水解酶的表征 Characterization of multiple forms of cholesteryl ester hydrolase in the rat testis. |
| 已发布 PubMed:固醇氧功能对与磷脂相互作用的影响。 The effect of the sterol oxygen function on the interaction with phospholipids. |
| 已发布 PubMed:固醇核对家蚕生长发育的结构要求。 Structural requirement of sterol nucleus for the silkworm growth and development. |
| 已发布 PubMed:固醇羟基在膜中的作用 On the role of the sterol hydroxyl group in membranes. |
| 已发布 PubMed:四氧化固定组织。蛋白质的可能作用。 Tissue fixation by osmium tetroxide. A possible role for proteins. |
| 已发布 PubMed:从胆固醇的选定的n-酰基酯的固溶体中氢化可的松的表面张力降低和溶解速率。 Surface tension lowering and dissolution rate of hydrocortisone from solid solutions of selected n-acyl esters of cholesterol. |
| 已发布 PubMed:皮（鞘翅目）胆固醇酯水解酶的研究。 Studies on the cholesterol ester hydrolase of Trogoderma (Coleoptera). |
| 已发布 PubMed:羊水中的胆固醇 Cholesterol in amniotic fluid, 通过气相色谱法测定。 determined by gas chromatography. |
| 已发布 PubMed:脂质药物输送系统对酸不稳定的抗生素的口服吸收效率。 Oral absorption efficiency of acid-labile antibiotics from lipid-drug delivery systems. |
| 已发布 PubMed:和混合单层胆固醇酯的性质 Properties of cholesteryl esters in pure and mixed monolayers. |
| 已发布 PubMed:的相互作用二氧化氮与胆固醇单分子膜 The interaction of nitrogen dioxide with monomolecular films of cholesterol, 二氢胆固醇 dihydrocholesterol, 和胆固醇胆固醇。 and cholesteryl acetate. |
| 已发布 PubMed:离子通道和橙花膜脂质。胆固醇-河豚毒素相互作用。 Ionic channels and nerve membrane lipids. Cholesterol-tetrodotoxin interaction. |
| 已发布 PubMed:成年大鼠大脑特征性酯酶的纯化和性质。 Purification and properties of esterases characteristic of adult rat brain. |
| 已发布 PubMed:合成 Synthesis, 7-酮胆固醇和差向异构7-羟基胆固醇的纯化和表征。 purification and characterization of 7-ketocholesterol and epimeric 7-hydroxycholesterols. |
| 已发布 PubMed:牛肾上腺皮质胆固醇氧化酶的底物和抑制剂特异性 Substrate and inhibitor specificity of the cholesterol oxidase in bovine adrenal cortex. |
| 已发布 PubMed:胆甾醇乙酸酯制备双环胆甾烯。 Preparation of bicholestatriene from cholesteryl-acetate. |
| 已发布 PubMed:抑制溶血的机制 THE MECHANISM OF THE INHIBITION OF HEMOLYSIS : iii。溶胶抑制与胆固醇有关的物质。 III. INHIBITION BY SOLS OF SUBSTANCES RELATED TO CHOLESTEROL. |
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大戟科龙骨提取物梅尼兰提取物阿玛鲁斯提取物阿弗拉提斯提取物丝状提取物费拉菲提取物extract子提取物la子提取物extract子提取物。得体提取物phyllanthus microphyllus提取物phyllanthus niruri亚种。甲状旁腺提取物phyllanthus niruri var。 genuinus提取物quebra pedra提取物rami buah提取物碎石提取物turi hutan提取物 Cholesteryl acetate is a normal human cholesteryl ester present in diverse fluids and organs. Cholesteryl acetate is also present in foods. Food oxidation affects the quality and safety of the human diet by generating compounds with biological activities that can adversely affect health. In particular the susceptibility of cholesterol to oxidation is well known; certain products of cholesterol oxidation have been reported to produce cytotoxic, 血管毒性和致癌作用。胆固醇酯（ce）是脂蛋白颗粒和大多数细胞类型中胆固醇的主要运输和储存形式。 ce物种的分子组成对动脉硬化研究非常感兴趣 angiotoxic and carcinogenic effects. Cholesteryl ester (CE) is the major transport and storage form of cholesterol in lipoprotein particles and most cell types. Molecular composition of CE species is of high interest for arteriosclerosis research, 即 i.e., 作为脂蛋白亚类的组成部分，或在研究与脂质负载泡沫细胞生成有关的机制的研究中。从而 as components of lipoprotein subclasses or in studies investigating the mechanisms involved in the generation of lipid laden foam cells. Thus, 研究表明，循环血浆中的 物种与冠心病的发展密切相关。这可能与参与脂蛋白代谢的酶（如卵磷脂）产生的特定ce物种谱有关 it has been shown that CE species in circulating plasma are strongly correlated with development of coronary heart disease. This may be related to specific CE species profiles generated by enzymes involved in lipoprotein metabolism like lecithin:胆固醇酰基转移酶（ec 2.3.1.43 cholesterol acyltransferase (EC 2.3.1.43, lcat） LCAT), 酰基辅酶a acyl-coenzyme A:胆固醇酰基转移酶2（ec 2.3.1.26 cholesterol acyltransferase 2 (EC 2.3.1.26, acat2）或胆固醇酯转移蛋白（cetp）。胆固醇酯转移蛋白在高密度脂蛋白（hdl）的代谢中起关键作用 ACAT2) or cholesteryl ester transfer protein (CETP). The cholesteryl ester transfer protein has a key role in the metabolism of high-density lipoprotein (HDL), 介导脂蛋白之间的脂质交换 mediating the exchange of lipids between lipoproteins, 导致胆固醇酯从hdl净转移到其他脂蛋白，并随后被肝细胞吸收胆固醇。通过增加低密度和非常低密度脂蛋白的胆固醇酯含量 resulting in the net transfer of cholesteryl ester from HDL to other lipoproteins and in the subsequent uptake of cholesterol by hepatocytes. By increasing the cholesteryl ester content of low-density and very-low-density lipoproteins, cetp促进这些脂蛋白的动脉粥样硬化。此外 CETP promotes the atherogenicity of these lipoproteins. In addition, 高血浆浓度的cetp与降低的hdl胆固醇浓度有关。 （pmid high plasma concentrations of CETP are associated with reduced concentrations of HDL cholesterol. (PMID: 10918380, 16458590, 9420339, 3343104, 6721900, 7278520）[hmdb] 7278520) [HMDB]
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3D/INCHI