已发布 PubMed:酪氨酸联合丁胺卡那霉素对铜绿假单胞菌生物膜的影响 The effects of D-Tyrosine combined with amikacin on the biofilms of Pseudomonas aeruginosa. |
已发布 PubMed:连续的酪氨酰-trna合成酶测定法,可重新生成trna底物。 A continuous tyrosyl-tRNA synthetase assay that regenerates the tRNA substrate. |
已发布 PubMed:枯草芽孢杆菌对d-氨基酸具有抗性的突变的鉴定和表征。 Identification and characterization of mutations conferring resistance to D-amino acids in Bacillus subtilis. |
已发布 PubMed: 枯草芽孢杆菌tyrz基因编码高度选择性的酪氨酰-trna合成酶,并受marr调节剂和t 框 box核糖开关的调节。 |
已发布 PubMed:新型环肽的抗炎活性 Anti-inflammatory activity of a new cyclic peptide, citrusin XI, 从柑桔类水果中分离出来。 isolated from the fruits of Citrus unshiu. |
已发布 PubMed:电喷雾电离串联质谱法测定去甲酚碱和巯基立体异构体的手性。 Chiral differentiation of the noscapine and hydrastine stereoisomers by electrospray ionization tandem mass spectrometry. |
已发布 PubMed:外切酶转换磁性纳米颗粒的表面,以选择性结合癌细胞。 Ectoenzyme switches the surface of magnetic nanoparticles for selective binding of cancer cells. |
已发布 PubMed:银纳米粒子作为光学传感器,基于减少的共振散射信号,对酪氨酸对映体进行手性识别。 Chiral recognition of tyrosine enantiomers based on decreased resonance scattering signals with silver nanoparticles as optical sensor. |
已发布 PubMed: 来自解淀粉芽孢杆菌的dtd dtd基因编码一个推定的d-酪氨酰-三苯甲基脱酰基酶,并且是枯草芽孢杆菌的选择性标记。 |
已发布 PubMed:磷酸盐修饰的磁性纳米粒子的酶促转化,用于选择性分选和抑制癌细胞。 Enzymatic transformation of phosphate decorated magnetic nanoparticles for selectively sorting and inhibiting cancer cells. |
已发布 PubMed:d-氨基酸抑制初始细菌粘附 D-amino acids inhibit initial bacterial adhesion: 热力学证据。 thermodynamic evidence. |
已发布 PubMed:ag交换的沸石和d-酪氨酸对pvc复合材料对鲍曼不动杆菌临床分离株的协同抗生物结垢作用。 Synergistic anti-biofouling effect of Ag-exchanged zeolite and D-Tyrosine on PVC composite against the clinical isolate of Acinetobacter baumannii. |
已发布 PubMed:嗜热细菌风杆菌木聚糖的一种高度稳定的d-氨基酸氧化酶。 A Highly Stable D-Amino Acid Oxidase of the Thermophilic Bacterium Rubrobacter xylanophilus. |
已发布 PubMed: 酪氨酸酶能够氧化杜鹃醇的两种对映体。 Human tyrosinase is able to oxidize both enantiomers of rhododendrol. |
已发布 PubMed: 氨基酸代谢在幼年仓鼠(p。太阳神 sungorus)和罗博罗夫斯基 roborovskii仓鼠(p。罗博罗夫斯基 roborovskii)的大脑中有所不同。 |
已发布 PubMed:d-氨基酸自组装肽可增强10-羟基喜树碱选择性和抗肿瘤功效。 Self-assembling peptide of D-amino acids boosts selectivity and antitumor efficacy of 10-hydroxycamptothecin. |
已发布 PubMed:氨基酸和去甲精胺对大分子分解的影响 Effects of D-amino acids and norspermidine on the disassembly of large, 老年微生物聚集体。 old-aged microbial aggregates. |
已发布 PubMed:酪氨酸对活性污泥絮凝物稳定性的影响 Influences of D-tyrosine on the stability of activated sludge flocs. |
已发布 PubMed:d-氨基酸通过干扰蛋白质合成来间接抑制枯草芽孢杆菌中生物膜的形成。 D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis. |
已发布 PubMed:计算蛋白质设计 Computational protein design: proteus软件和选定的应用程序。 the Proteus software and selected applications. |
已发布 PubMed:喷雾干燥配方设计的基本方法的使用,以促进用于呼吸道药物递送的多组分干粉气雾剂的开发。 Use of a fundamental approach to spray-drying formulation design to facilitate the development of multi-component dry powder aerosols for respiratory drug delivery. |
已发布 PubMed:芽孢杆菌中环(d-tyr-1-leu)二酮哌嗪的分离及抗真菌特性与大戟杀虫 有关。 Isolation and antifungal properties of cyclo(D-Tyr-L-Leu) diketopiperazine isolated from Bacillus sp. associated with rhabditid entomopathogenic nematode. |
已发布 PubMed:酪氨酸替代物产生的降钙素基因相关肽(cgrp)受体拮抗剂的合成和sar。第2部分。 The synthesis and SAR of calcitonin gene-related peptide (CGRP) receptor antagonists derived from tyrosine surrogates. Part 2. |
已发布 PubMed:利用随机和定点诱变方法对细菌酪氨酸酶进行工程改造以提高对d-酪氨酸催化效率。 Engineering of a bacterial tyrosinase for improved catalytic efficiency towards D-tyrosine using random and site directed mutagenesis approaches. |
已发布 PubMed:作为新型正电子发射断层扫描氨基酸示踪剂的3-[((18)f]氟-α-甲基-d-酪氨酸(d-[(18)f] famt)的生物学评估。 Biological evaluation of 3-[(18)F]fluoro-α-methyl-D-tyrosine (D-[(18)F]FAMT) as a novel amino acid tracer for positron emission tomography. |
已发布 PubMed:将紫杉醇靶向递送至表达epha2的癌细胞。 Targeted delivery of paclitaxel to EphA2-expressing cancer cells. |
已发布 PubMed:伯克霍尔德菌属麦角硫醚酶的特性hme13及其在麦角硫氨酸酶促定量中的应用。 Characterization of ergothionase from Burkholderia sp. HME13 and its application to enzymatic quantification of ergothioneine. |
已发布 PubMed:酪氨酸利用率的增加会增加体内脑区域多巴的水平。 Increased tyrosine availability increases brain regional DOPA levels in vivo. |
已发布 PubMed:协同作用的d-酪氨酸和四羟甲基硫酸ty杀菌剂的组合,用于减轻srb生物膜。 A synergistic D-tyrosine and tetrakis hydroxymethyl phosphonium sulfate biocide combination for the mitigation of an SRB biofilm. |
已发布 PubMed:d-氨基酸,用于增强由thps和edds组成的二元杀菌剂混合物,对抗srb生物膜。 D-amino acids for the enhancement of a binary biocide cocktail consisting of THPS and EDDS against an SRB biofilm. |
已发布 PubMed:小径基因的共同递送增强了紫杉醇在体外和体内的抗胶质母细胞瘤作用。 Co-delivery of TRAIL gene enhances the anti-glioblastoma effect of paclitaxel in vitro and in vivo. |
已发布 PubMed:环状rgd-聚乙二醇-聚乙烯亚胺用于颅内成胶质细胞瘤靶向基因的递送。 Cyclic RGD-polyethylene glycol-polyethylenimine for intracranial glioblastoma-targeted gene delivery. |
已发布 PubMed:通过d-氨基酸抑制的ai-2和eps产生减少微生物附着。 Reduced microbial attachment by D-amino acid-inhibited AI-2 and EPS production. |
已发布 PubMed:使用烟曲霉l-氨基酸氧化酶消旋一些dl-氨基酸。 Racemic resolution of some DL-amino acids using Aspergillus fumigatus L-amino acid oxidase. |
已发布 PubMed:b。锚定和组装淀粉样蛋白纤维所需的辅助蛋白。枯草生物膜。 An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms. |
已发布 PubMed:芯片电泳-激光诱导荧光检测对生物样品中的d-酪氨酸进行痕量分析 Trace analysis of D-tyrosine in biological samples by microchip electrophoresis with laser induced fluorescence detection. |
已发布 PubMed:氨酰基辅酶,一种由产黄青霉的coa连接酶催化的合成。 Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum. |
已发布 PubMed:两种羟基肉桂酰基转移酶具有不同的底物特异性和异常的底物灵活性 Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, 迷迭香酸合酶和羟肉桂酰可可 rosmarinic acid synthase and hydroxycinnamoyl-CoA:莽草酸羟肉桂酰基转移酶 shikimate hydroxycinnamoyl-transferase, 来自锦紫苏明珠。 from Coleus blumei Benth. |
已发布 PubMed:卤代芳香族氨基酸3 Halogenated aromatic amino acid 3,5-二溴 5-dibromo-D: -酪氨酸在实验性中风和癫痫发作中产生有益作用。 -tyrosine produces beneficial effects in experimental stroke and seizures. |
已发布 PubMed:β-环糊精衍生物与手性发色性取代基对类固醇选择性结合的热力学起源。 Thermodynamic origin of selective binding of β-cyclodextrin derivatives with chiral chromophoric substituents toward steroids. |
已发布 PubMed:d-tyr-trna(tyr)脱酰基酶 D-Tyr-tRNA(Tyr) deacylase, a new role in Alzheimer's-关联的 associated 疾病 disease in SAMP8 老鼠 mice. |
已发布 PubMed:居家来源的cu kalpha和中等质量的碘化物-sad数据分析d-酪氨酰-三苯甲基脱酰基酶的结构 Structure of D-tyrosyl-tRNATyr deacylase using home-source Cu Kalpha and moderate-quality iodide-SAD data: 结构多态性和结合hepes的酶态。 structural polymorphism and HEPES-bound enzyme states. |
已发布 PubMed:d-氨基酸触发生物膜分解。 D-amino acids trigger biofilm disassembly. |
已发布 PubMed:jmjd2组蛋白脱甲基酶的选择性抑制剂 Selective inhibitors of the JMJD2 histone demethylases: 结合了非变性质谱筛查和晶体学方法。 combined nondenaturing mass spectrometric screening and crystallographic approaches. |
已发布 PubMed:环状rgd共轭聚乙二醇-共聚乳酸胶束可增强紫杉醇抗成胶质细胞瘤的作用。 Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect. |
已发布 PubMed:苯丙氨酸取代的蛙皮素片段与粗糙化ag之间相互作用的电位依赖性研究 Potential-dependent studies on the interaction between phenylalanine-substituted bombesin fragments and roughened Ag, au Au, 和铜电极表面。 and Cu electrode surfaces. |
已发布 PubMed:9位含非天然氨基酸催产素类似物的合成及生物学活性 Synthesis and biological activity of oxytocin analogues containing unnatural amino acids in position 9: 结构活动研究。 structure activity study. |
已发布 PubMed:多肽的吸附机理及其在疏水界面的位置 Adsorption mechanism of polypeptides and their location at hydrophobic interfaces. |
已发布 PubMed:靶向整联蛋白的超声微泡在鼠肿瘤模型中的停留时间较长。 Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. |
已发布 PubMed:抗d-氨基酰基-trnas的细胞防御的广泛分布。 Widespread distribution of cell defense against D-aminoacyl-tRNAs. |
已发布 PubMed:-[(18)f]氟甲基-d-酪氨酸作为放射性示踪剂对正电子发射断层扫描技术进行肿瘤成像的评价 Evaluation of O-[(18)F]fluoromethyl-D-tyrosine as a radiotracer for tumor imaging with positron emission tomography. |
已发布 PubMed: 芽孢杆菌中氟化伊图林 iturin a的前体定向生物合成。 |
已发布 PubMed:d-18f-fmt的评估 Evaluation of D-18F-FMT, 18f-fdg 18F-FDG, l-11c-met L-11C-MET, 和18f-flt用于监测小鼠对放疗的肿瘤反应。 and 18F-FLT for monitoring the response of tumors to radiotherapy in mice. |
已发布 PubMed:胃溃疡和胃癌相关幽门螺杆菌菌株的基因组序列分析 Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer. |
已发布 PubMed: 类d-tyr-trna(tyr)脱酰基酶有助于细胞抵抗d-氨基酸。 Human D-Tyr-tRNA(Tyr) deacylase contributes to the resistance of the cell to D-amino acids. |
已发布 PubMed:对映体控制(-)-9-表喷他佐辛和(-)-甲啡肽的合成。 Enantiocontrolled synthesis of (-)-9-epi-pentazocine and (-)-aphanorphine. |
已发布 PubMed:嗜热脂肪芽孢杆菌酪氨酰-trna合成酶激活d-酪氨酸 Activation of D-tyrosine by Bacillus stearothermophilus tyrosyl-tRNA synthetase: 1.稳态前动力学分析揭示了识别d-酪氨酸机理基础。 1. Pre-steady-state kinetic analysis reveals the mechanistic basis for the recognition of D-tyrosine. |
已发布 PubMed:嗜热脂肪芽孢杆菌酪氨酰-trna合成酶激活d-酪氨酸 Activation of D-tyrosine by Bacillus stearothermophilus tyrosyl-tRNA synthetase: 2. atp的协同结合仅限于酶的初始转换。 2. Cooperative binding of ATP is limited to the initial turnover of the enzyme. |
已发布 PubMed:实验证据导致对为什么d-酪氨酸有时比其l-对映体结晶更快的解释。 Experimental evidence leading to an alternative explanation of why D-tyrosine sometimes crystallizes faster than its L-enantiomer. |
已发布 PubMed:酪氨酸拮抗剂在 p2x7受体上的合成及构效关系研究。 Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor. |
已发布 PubMed:新型凝血酶抑制剂的结构,其中不带电荷的d-氨基酸为p1残基。 Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue. |
已发布 PubMed:pd(0)催化的分子内恶嗪形成在(-)-茴香霉素有效全合成中的应用 Application of Pd(0)-catalyzed intramolecular oxazine formation to the efficient total synthesis of (-)-anisomycin. |
已发布 PubMed:与r1m横纹肌肉瘤的wag / rij大鼠相比,d-和l- [123i] -2-i-苯丙氨酸与d-和l- [123i] -2-i-酪氨酸相比具有更长的肿瘤保留时间。 D- and L-[123I]-2-I-phenylalanine show a long tumour retention compared with D- and L-[123I]-2-I-tyrosine in R1M rhabdomyosarcoma tumour-bearing Wag/Rij rats. |
已发布 PubMed:合成甘露肽霉素-e的糖基化酪氨酸部分的氮杂类似物。 Synthesis of aza-analogues of the glycosylated tyrosine portion of mannopeptimycin-E. |
已发布 PubMed:固定在手性和非手性支持物上的蘑菇酪氨酸酶的立体特异性。 Stereospecificity of mushroom tyrosinase immobilized on a chiral and a nonchiral support. |
已发布 PubMed:优选将邻-(2- [18f]氟乙基)-d-酪氨酸(d-fet)转运到猪脑中。 Preferred transport of O-(2-[18F]fluoroethyl)-D-tyrosine (D-FET) into the porcine brain. |
已发布 PubMed:gek1 GEK1, 拟南芥参与乙醇耐受的基因产物 a gene product of Arabidopsis thaliana involved in ethanol tolerance, 是d-氨基酰基-trna脱酰基酶。 is a D-aminoacyl-tRNA deacylase. |
已发布 PubMed:重组乙内酰脲酶基因的多顺反子结构,用于生产光学纯的d-氨基酸。 Recombinant polycistronic structure of hydantoinase process genes in Escherichia coli for the production of optically pure D-amino acids. |
已发布 PubMed:d-谷氨酸在大鼠脑中的免疫细胞化学可视化。 Immunocytochemical visualization of D-glutamate in the rat brain. |
已发布 PubMed:r1m横纹肌肉瘤细胞和体内荷瘤r1m的wag / rij大鼠体内[123 / 125i] -2-碘-d-酪氨酸和[123 / 125i] -2-碘-1-酪氨酸摄取的比较。 Comparison of the uptake of [123/125I]-2-iodo-D-tyrosine and [123/125I]-2-iodo-L-tyrosine in R1M rhabdomyosarcoma cells in vitro and in R1M tumor-bearing Wag/Rij rats in vivo. |
已发布 PubMed:Vegf-a165诱导的血管生成通过蛋白激酶D酪氨酸磷酸化的作用,需要通过其相互作用和磷脂酶Camma磷酸化的调节来实现。 Requirement of protein kinase D tyrosine phosphorylation for VEGF-A165-induced angiogenesis through its interaction and regulation of phospholipase Cgamma phosphorylation. |
已发布 PubMed:新型d-tyr-trnatyr脱酰基酶的古细菌鉴定。 Identification in archaea of a novel D-Tyr-tRNATyr deacylase. |
已发布 PubMed:-18f-氟甲基的d-异构体的评价 Evaluation of D-isomers of O-18F-fluoromethyl, o-18f-氟乙基和o-18f-氟丙基酪氨酸在小鼠中作为肿瘤显像剂。 O-18F-fluoroethyl and O-18F-fluoropropyl tyrosine as tumour imaging agents in mice. |
已发布 PubMed:强力的设计与合成 Design and synthesis of potent, 高选择性加压素降压激动剂。 highly selective vasopressin hypotensive agonists. |
已发布 PubMed:甘露肽霉素的合成研究 Synthetic studies toward mannopeptimycin-E: 邻位酪氨酸合成1 synthesis of the O-linked tyrosine 1,4-alpha 4-alpha,阿尔法曼诺 alpha-manno,甘露聚糖-吡喃糖基吡喃糖苷。 manno-pyranosyl pyranoside. |
已发布 PubMed:萘甲酰胺a的完全立体化学和巴布酰胺b中的β-甲氧基酪氨酸残基的精华/精粹/精萃构型。 Complete stereochemistry of neamphamide A and absolute configuration of the beta-methoxytyrosine residue in papuamide B. |
已发布 PubMed:简化β-甲氧基酪氨酸所有立体异构体的合成,并确定卡培尔汀中残基的精华/精粹/精萃构型 Concise synthesis of all stereoisomers of beta-methoxytyrosine and determination of the absolute configuration of the residue in callipeltin A. |
已发布 PubMed:多羟基化吡咯烷的α-鼠李糖苷酶抑制活性。 Alpha-rhamnosidase inhibitory activities of polyhydroxylated pyrrolidine. |
已发布 PubMed:纯化 Purification, 表征 characterization, d的基因克隆和核苷酸测序 gene cloning and nucleotide sequencing of D: 土壤细菌的β-立体特异性氨基酸酰胺酶 -stereospecific amino acid amidase from soil bacterium: 嗜酸delftia。 Delftia acidovorans. |
已发布 PubMed:新型真菌代谢产物(-)-木糖酰胺的分离与结构鉴定 Isolation and structure elucidation of the new fungal metabolite (-)-xylariamide A. |
已发布 PubMed:氨酰基-trna合成酶将大肠杆菌trnas与d-组氨酸和d-赖氨酸酯化。 Esterification of Escherichia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases. |
已发布 PubMed:d-酪氨酸中茴香霉素衍生物的立体发散性合成。 Stereodivergent syntheses of anisomycin derivatives from D-tyrosine. |
已发布 PubMed:辣根过氧化物酶的立体特异性。 Stereospecificity of horseradish peroxidase. |
已发布 PubMed:古细菌招募了d-tyr-trnatyr脱酰基酶来编辑thr-trna合成酶。 Archaea recruited D-Tyr-tRNATyr deacylase for editing in Thr-tRNA synthetase. |
已发布 PubMed:铜绿假单胞菌pao1中的嘧啶泛铁生物合成所需的氨基转移酶的功能表征。 Functional characterization of an aminotransferase required for pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa PAO1. |
已发布 PubMed:d-酪氨酰-三萘啶的形成解释了d-酪氨酸对大肠杆菌的毒性。 Formation of D-tyrosyl-tRNATyr accounts for the toxicity of D-tyrosine toward Escherichia coli. |
已发布 PubMed:(+)-隐霉素52(ly355703)的对映选择性合成 Enantioselective synthesis of (+)-cryptophycin 52 (LY355703), 一种有效的抗有丝分裂抗肿瘤药。 a potent antimitotic antitumor agent. |
已发布 PubMed:d-氨基酸和d-tyr-trna(tyr)脱酰基酶 D-Amino acids and D-Tyr-tRNA(Tyr) deacylase: 再谈翻译机的立体特质。 stereospecificity of the translation machine revisited. |
已发布 PubMed:胰蛋白酶催化水解某些精氨酸肽甲基酯的动力学 [Kinetics of trypsin-catalyzed hydrolysis of some arginine-containing peptide methyl esters]. |
已发布 PubMed:在策略性酪氨酸残基处通过立体异构取代来探测通道结合的振荡器b失活肽。 Probing the channel-bound shaker B inactivating peptide by stereoisomeric substitution at a strategic tyrosine residue. |
已发布 PubMed:氨基酸对大鼠肝脏某些线粒体功能的影响 Effect of D-amino acids on some mitochondrial functions in rat liver. |
已发布 PubMed:d-酪氨酸是具有抗炎活性的 非胰腺分泌型磷脂酶a2(iia)的强效抑制剂的手性前驱物。 D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. |
已发布 PubMed:铜绿素ei461的推定结构和修饰结构的合成,带有一个新的双环α-氨基酸。 Syntheses of both the putative and revised structures of aeruginosin EI461 bearing a new bicyclic alpha-amino acid. |
已发布 PubMed:流感嗜血杆菌hi0670晶体结构的d-tyr-trnatyr脱酰基酶催化机理 A catalytic mechanism for D-Tyr-tRNATyr deacylase based on the crystal structure of Hemophilus influenzae HI0670. |
已发布 PubMed:d-酪氨酸和l-酪氨酸之间出乎意料的差异导致外消旋混合物中的手性增强。 Unexpected differences between D- and L- tyrosine lead to chiral enhancement in racemic mixtures. |
已发布 PubMed:设计 Design, 新型高选择性crf(2)拮抗剂的合成与药理学表征 synthesis and pharmacological characterization of new highly selective CRF(2) antagonists: 开发123i-k31440作为潜在的斑点配体。 development of 123I-K31440 as a potential SPECT ligand. |
已发布 PubMed:结晶d-tyr-trna(tyr)脱酰基酶的结构。一类新的依赖于trna的水解酶的代表。 Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases. |
已发布 PubMed: 抗肿瘤缩肽(-)-多核苷 -doliculide的全合成。 |
已发布 PubMed:检测和新型微生物d-氨基酸氧化酶的底物选择性。 Detection and substrate selectivity of new microbial D-amino acid oxidases. |
已发布 PubMed:d-氨基酰基-trnas在大肠杆菌和酿酒酵母细胞中的代谢 Metabolism of D-aminoacyl-tRNAs in Escherichia coli and Saccharomyces cerevisiae cells. |
已发布 PubMed:甲状腺素类似物对 肝脏3α-羟类固醇脱氢酶的结构特异性作用。 Structure-specific effects of thyroxine analogs on human liver 3 alpha-hydroxysteroid dehydrogenase. |
已发布 PubMed:酿酒酵母中的d-酪氨酰-trna(tyr)代谢。 D-tyrosyl-tRNA(Tyr) metabolism in Saccharomyces cerevisiae. |
已发布 PubMed:化学 Chemistry, 营养 nutrition, 和d-氨基酸微生物学。 and microbiology of D-amino acids. |
已发布 PubMed:加压素降压肽激动剂的合成及结构活性研究 Synthesis and structure-activity investigation of novel vasopressin hypotensive peptide agonists. |
已发布 PubMed:大肠杆菌d-tyr-trnatyr脱酰基酶的功能表征。 Functional characterization of the D-Tyr-tRNATyr deacylase from Escherichia coli. |
已发布 PubMed:d-酪氨酸两亲性癸酯自组装胶束小管的石英微平衡测量及其酶促聚合 Quartz crystal microbalance measurement of self-assembled micellar tubules of the amphiphilic decyl ester of D-tyrosine and their enzymatic polymerization. |
已发布 PubMed:带有二亚乙基三胺五乙酸含d-氨基酸放射性碘标记肽标记单克隆抗体。 Labeling of monoclonal antibodies with diethylenetriaminepentaacetic acid-appended radioiodinated peptides containing D-amino acids. |
已发布 PubMed:-(2- [18f]氟乙基)-1-酪氨酸合成及放射药理学意义。 Synthesis and radiopharmacology of O-(2-[18F]fluoroethyl)-L-tyrosine for tumor imaging. |
已发布 PubMed:受损整合素介导的成纤维细胞表达显性负突变体ptp1b的粘附和信号转导。 Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. |
已发布 PubMed: 脂多糖诱导肺泡巨噬细胞中可诱导型一氧化氮合酶姆纳 mRNA的潜在机制及其乙醇抑制 , 体内。 in vivo. |
已发布 PubMed:酪氨酸酶的立体特异性研究。 Study of stereospecificity in mushroom tyrosinase. |
已发布 PubMed:精氨酸血管加压素v1a受体在交感肾上腺橙花节前橙花元上的定位。 Localisation of arginine vasopressin V1a receptors on sympatho-adrenal preganglionic neurones. |
已发布 PubMed:新型抗 血管加压素v2和v1a受体的放射性碘标记拮抗剂的性质。 Properties of a new radioiodinated antagonist for human vasopressin V2 and V1a receptors. |
已发布 PubMed:加压素拮抗剂中的第3位可耐受构象受限和芳香族氨基酸取代 Position three in vasopressin antagonist tolerates conformationally restricted and aromatic amino acid substitutions: 与加压素激动剂形成鲜明对比。 a striking contrast with vasopressin agonists. |
已发布 PubMed:不可降解肽的吸收和排泄 Absorption and excretion of undegradable peptides: 脂质溶解度和净电荷的作用。 role of lipid solubility and net charge. |
已发布 PubMed:酪氨酸酶促和非酶促氧化。 Enzymatic and non-enzymatic oxygenation of tyrosine. |
已发布 PubMed:-asp-血管紧张素i的d-氨基酸取代类似物对血管紧张素iii的中枢加压作用。 Actions of D-amino acid-substituted analogues of des-Asp-angiotensin I on the central pressor action of angiotensin III. |
已发布 PubMed:d-氨基酸在慢性肾功能衰竭以及透析和尿流失的影响。 D-Amino acids in chronic renal failure and the effects of dialysis and urinary losses. |
已发布 PubMed:对 脑动脉加压素和去氨加压素的反应。 Responses to vasopressin and desmopressin of human cerebral arteries. |
已发布 PubMed:多巴胺和前体氨基酸抑制色氨酸羟化酶。 Inhibition of tryptophan hydroxylase by dopamine and the precursor amino acids. |
已发布 PubMed:以左旋酪氨酸为底物的真核植物酚磺基转移酶的纯化及性质 Purification and properties of a phenol sulphotransferase from Euglena using L-tyrosine as substrate. |
已发布 PubMed:绿豆中的氨基酸n-丙二酸转移酶。作用于1-氨基环丙烷-1-羧酸和d-苯丙氨酸。 Amino acid N-malonyltransferases from mung beans. Action on 1-aminocyclopropane-1-carboxylic acid and D-phenylalanine. |
已发布 PubMed:新的抗 抗生素 New antiviral antibiotics, 庆大霉素a和b。 ii。结构确定。 kistamicins A and B. II. Structure determination. |
已发布 PubMed:荧光和生物素化的线性肽作为v1a血管加压素受体的选择性双功能配体。 Fluorescent and biotinylated linear peptides as selective bifunctional ligands for the V1a vasopressin receptor. |
已发布 PubMed:酶催化酪氨酸碘化反应的动力学和机理 Kinetics and mechanism of the peroxidase-catalyzed iodination of tyrosine. |
已发布 PubMed:去除稳定的酪氨酸基团d +会影响到来自集囊藻6803的贫锰光系统ii颗粒中酪氨酸z的结构或氧化还原特性。 Removal of stable tyrosine radical D+ affects the structure or redox properties of tyrosine Z in manganese-depleted photosystem II particles from Synechocystis 6803. |
已发布 PubMed:具有C末端乙二胺连接的逆向氨基酸强效v2 / v1a加压素拮抗剂。 Potent V2/V1a vasopressin antagonists with C-terminal ethylenediamine-linked retro-amino acids. |
已发布 PubMed:卤素原子对蛋白质-配体相互作用的贡献。 The contribution of halogen atoms to protein-ligand interactions. |
已发布 PubMed:绑定但不激活v1或v2受体的加压素类似物并未内化到表达v1或v2受体的细胞中。 A vasopressin analog that binds but does not activate V1 or V2 vasopressin receptors is not internalized into cells that express V1 or V2 receptors. |
已发布 PubMed:体外循环期间急性脑低氧的代谢方面及其通过乙酰肉碱治疗引起的修饰。 Metabolic aspects of acute cerebral hypoxia during extracorporeal circulation and their modification induced by acetyl-carnitine treatment. |
已发布 PubMed:酪氨酸与辣根过氧化物酶和乳过氧化物酶的立体选择性相互作用的光谱和结合研究。 Spectroscopic and binding studies on the stereoselective interaction of tyrosine with horseradish peroxidase and lactoperoxidase. |
已发布 PubMed:催产素拮抗剂(dtvt)和利多君对妊娠大鼠自发和催产素引起的子宫收缩的作用。 Effects of oxytocin antagonist (dTVT) and ritodrine on spontaneous and oxytocics-induced uterine contractions in pregnant rats. |
已发布 PubMed:黑素瘤细胞上的l-酪氨酸结合蛋白。 L-tyrosine-binding proteins on melanoma cells. |
已发布 PubMed:Formation, 营养价值 nutritional value, 和d-氨基酸安全性。 and safety of D-amino acids. |
已发布 PubMed: 胎盘左酪氨酸转运 Human placental L-tyrosine transport: 刷状边界和基底膜囊泡的比较es。 a comparison of brush-border and basal membrane vesicles. |
已发布 PubMed:[1-(β-巯基-β Efficient solution phase synthesis of [1-(beta-mercapto-beta, β-环五亚甲基丙酸)-2-(邻乙基-d-酪氨酸)-4-缬氨酸-9-去甘氨酸]精氨酸加压素。 beta-cyclopentamethylenepropionic acid)- 2-(O-ethyl-D-tyrosine)-4-valine-9-desglycine]arginine vasopressin. |
已发布 PubMed:一碘代酪氨酸 Monoiodo-D-tyrosine, 一种 工氨基酸放射性药物,用于选择性测量胰腺中膜氨基酸转运。 an artificial amino acid radiopharmaceutical for selective measurement of membrane amino acid transport in the pancreas. |
已发布 PubMed:非环状加压素类似物在清醒大鼠中是有效的利尿剂。 Noncyclic vasopressin analogs are effective diuretics in conscious rats. |
已发布 PubMed:真核信号肽酶的合成底物。甲状旁腺原激素前体区域的合成肽类似物的裂解。 Synthetic substrate for eukaryotic signal peptidase. Cleavage of a synthetic peptide analog of the precursor region of preproparathyroid hormone. |
已发布 PubMed:五种新的avp v1或v1 / v2拮抗剂的合成和某些药理特性。 Synthesis and some pharmacologic properties of five novel V1 or V1/V2 antagonists of AVP. |
已发布 PubMed:d-苯丙氨酸和d-酪氨酸与羧肽酶的结合 Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. |
已发布 PubMed:一种来自拟 och 的新的d-立体特异性氨基酸酰胺酶。 A new D-stereospecific amino acid amidase from Ochrobactrum anthropi. |
已发布 PubMed:子宫肌层和蜕膜中的催产素拮抗剂(dtvt)和催产素受体。 Oxytocin antagonist (dTVT) and oxytocin receptors in myometrium and decidua. |
已发布 PubMed:在有效的加压素拮抗剂中对残基1的微小修饰会大大降低激动剂的活性。 A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activity. |
已发布 PubMed:马氏红球菌k-18的二聚苯丙氨酸脱氢酶的纯化和表征。 Purification and characterization of a dimeric phenylalanine dehydrogenase from Rhodococcus maris K-18. |
已发布 PubMed:有意识的狗出血后v1 vs. v1 + v2联合加压素阻断。 V1 vs. combined V1+V2 vasopressin blockade after hemorrhage in conscious dogs. |
已发布 PubMed:使用n Use of N,o-bis-fmoc-d-tyr-onsu,用于将氧化碘化位点引入胆囊收缩素家族肽。 O-bis-Fmoc-D-Tyr-ONSu for introduction of an oxidative iodination site into cholecystokinin family peptides. |
已发布 PubMed:黑素生成途径的两个关键底物对黑素色素沉着的正向调节 Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, 左旋酪氨酸和左旋多巴 L-tyrosine and L-dopa. |
已发布 PubMed:二维nmr数据对溶液中霉菌枯草素的构象进行建模和优化。 Modelling and refinement of the conformation of mycosubtilin in solution from two-dimensional NMR data. |
已发布 PubMed:蛋白激酶的立体特异性。 The stereospecificity of protein kinases. |
已发布 PubMed:具有激动和拮抗作用的加压素类似物的碘化 Iodination of vasopressin analogues with agonistic and antagonistic properties: 对血管和肾脏血管加压素受体的生物学特性和亲和力的影响。 effects on biological properties and affinity for vascular and renal vasopressin receptors. |
已发布 PubMed:对羟基ubenimex的合成。 Synthesis of p-hydroxyubenimex. |
已发布 PubMed: 松鼠猴(saimiri 剑叶属 sciureus)中的加压素拮抗作用。 |
已发布 PubMed:降压药和抗利尿剂拮抗剂使肾血管加压素刺激的腺苷酸环化酶脱敏 Desensitization of renal vasopressin-stimulated adenylate cyclase by a vasopressor and antidiuretic antagonist, [1-(β-巯基-β Efficient solution phase synthesis of [1-(beta-mercapto-beta,β-环五亚甲基丙酸) beta-cyclopentamethylenepropionic acid),2-(邻乙基)-d-酪氨酸 2-(O-ethyl)-D-tyrosine, 4-缬氨酸]精氨酸加压素。 4-valine]arginine vasopressin. |
已发布 PubMed:胎盘胰岛素受体/激酶的底物特异性和动力学机制 Substrate specificity and kinetic mechanism of human placental insulin receptor/kinase. |
已发布 PubMed:培养基对枯草芽孢杆菌生产尿素a的影响 Influence of the culture medium on the production of iturin A by Bacillus subtilis. |
已发布 PubMed:血管加压素介导的对心房利钠因子刺激的cgmp积累在已建立的平滑肌细胞系中的抑制作用。 Vasopressin-mediated inhibition of atrial natriuretic factor-stimulated cGMP accumulation in an established smooth muscle cell line. |
已发布 PubMed:加压素类似物抑制醉鱼草膀胱经上皮水通量的作用机理和结构要求。 Mechanism of action and structural requirements of vasopressin analog inhibition of transepithelial water flux in toad urinary bladder. |
已发布 PubMed:加压素拮抗剂对下腔静脉狭窄中水分排泄的影响 Effect of vasopressin antagonist on water excretion in inferior vena cava constriction. |
已发布 PubMed:血管收缩素在脱水狗中被阻断后,其抗利尿作用的心血管效应。 Cardiovascular effects associated with antidiuretic activity of vasopressin after blockade of its vasoconstrictor action in dehydrated dogs. |
已发布 PubMed:腺苷受体拮抗剂的功能化同类方法 A functionalized congener approach to adenosine receptor antagonists: 1的氨基酸缀合物 amino acid conjugates of 1,3-二丙基黄嘌呤。 3-dipropylxanthine. |
已发布 PubMed:酪氨酸可用性阻止了酪胺引起的离体大鼠心脏的速激肽反应。 Tyrosine availability prevents tyramine-induced tachyphylaxis in the isolated rat heart. |
已发布 PubMed:加压素和催产素在体外刺激大鼠心室旁核中的橙花元。 Excitation of neurones in the rat paraventricular nucleus in vitro by vasopressin and oxytocin. |
已发布 PubMed:与d-苯丙氨酸相比,某些羧肽酶a抑制剂具有抗伤害作用。 Antinociceptive effect of some carboxypeptidase A inhibitors in comparison with D-phenylalanine. |
已发布 PubMed:饮食中的d-酪氨酸作为抗代谢物在小鼠中。 Dietary D-tyrosine as an antimetabolite in mice. |
已发布 PubMed:d-苯丙氨酸和d-酪氨酸在小鼠中的营养价值和安全性。 The nutritive value and safety of D-phenylalanine and D-tyrosine in mice. |
已发布 PubMed:中间柠檬酸杆菌酪氨酸酚裂解酶的分离及性质 [Isolation and properties of tyrosine phenol-lyase from Citrobacter intermedius]. |
已发布 PubMed:悬浮液培养的烟草中的l-酪氨酸调节和生物合成通过脱氢脱氢酶进行。等来。 L-tyrosine regulation and biosynthesis via arogenate dehydrogenase in suspension-cultured cells of Nicotiana silvestris Speg. et Comes. |
已发布 PubMed:催产素激动剂的构象Conformational comparisons of oxytocin agonists, 部分激动剂 partial agonists, 和拮抗剂使用激光拉曼光谱和圆二色光谱。检查1-penicillamine和非对映异构体类似物。 and antagonists using laser Raman and circular dichroism spectroscopy. Examination of 1-penicillamine and diastereoisomeric analogues. |
已发布 PubMed:设计更有效的精氨酸-加压素抗利尿剂拮抗剂。 Design of more potent antagonists of the antidiuretic responses to arginine-vasopressin. |
已发布 PubMed:d-和l-酪氨酰转移核糖核酸在肽链延伸中的区别。 Discrimination between D- and L-tyrosyl transfer ribonucleic acids in peptide chain elongation. |
已发布 PubMed:杆菌霉素d的结构 Structure of bacillomycin D, 伊图林组的新抗生素。 a new antibiotic of the iturin group. |
已发布 PubMed:对黑素细胞刺激激素和相关肽的消旋作用。 Racemization effects on melanocyte-stimulating hormones and related peptides. |
已发布 PubMed:黑素细胞刺激激素类似物在2和4(7)位置修饰的合成和结构功能研究 Synthesis and structure-function studies of melanocyte stimulating hormone analogues modified in the 2 and 4(7) positions: 蛙皮黑素细胞和黑素瘤腺苷酸环化酶活性的比较 comparison of activities on frog skin melanophores and melanoma adenylate cyclase. |
已发布 PubMed:酪氨酸位点特异性氘化及其选择性离子监测方法的测定 Site-specific deuteration of tyrosine and their assay by selective ion monitoring method. |
已发布 PubMed:卢利伯林(促黄体激素释放激素)肽拮抗剂的合成及其生物学活性。 Synthesis and biological activity of peptide antagonists of luliberin (luteinizing hormone-releasing hormone). |
已发布 PubMed:高效液相色谱法对酪氨酸羟化酶活性进行高度灵敏的测定。 Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography. |
已发布 PubMed:d-酪氨酸可预防经多卡盐水处理的未切除直肠的大鼠的高血压。 d-Tyrosine prevents hypertension in DOCA-saline treated uninephrectomised rats. |
已发布 PubMed:芳基硫酸酯酶a和b对酪氨酸邻硫酸盐的活性。 The activity of arylsulfatase A and B on tyrosine O-sulfates. |
已发布 PubMed:反相高压液相色谱法分离肽激素非对映异构体影响催产素及其非对映异构体分离的因素-结构意义。 The separation of peptide hormone diastereoisomers by reverse phase high pressure liquid chromatography. Factors affecting separation of oxytocin and its diastereoisomers--structural implications. |
已发布 PubMed:在新西兰白兔中使用恒定输注技术测量蛋白质合成速率。 Use of the constant infusion technique for measuring rates of protein synthesis in the New Zealand White rabbit. |
已发布 PubMed:[杆菌素的结构 [The structure of bacillomycin L, an 抗生素 antibiotic from 芽孢杆菌 Bacillus subtilis (author's 翻译 transl)]. |
已发布 PubMed:茄 中1-苯丙氨酸氨解酶的调控 Regulation of L-phenylalanine ammonia-lyase from Rhizoctonia solani. |
已发布 PubMed:[霉菌枯草杆菌素的结构 [The structure of mycosubtilin, an 抗生素 antibiotic 隔离的 隔离 isolated from 芽孢杆菌 Bacillus subtilis (author's 翻译 transl)]. |
已发布 PubMed:小鼠中尿囊素抗体的形成。 v。与二硝基苯基异源载体缀合物一起培养的二硝基苯基-匙孔cyan血蓝蛋白引发的脾细胞的过半抗原反应。 Reaginic antibody formation in the mouse. V. Adoptive antihapten IgE antibody response of dinitrophenyl-keyhole limpet hemocyanin-primed spleen cells cultured with dinitrophenyl heterologous carrier conjugates. |
已发布 PubMed:d-酪氨酸在枯草芽孢杆菌23和168菌株中不同的抗代谢作用的分子基础。 Molecular basis for the differential anti-metabolite action of D-tyrosine in strains 23 and 168 of Bacillus subtilis. |
已发布 PubMed:d-酪氨酸抑制枯草芽孢杆菌生长的分子事件。 Molecular events in the growth inhibition of Bacillus subtilis by D-tyrosine. |
已发布 PubMed:植物醌的生物合成。高纯酸 Biosynthesis of phytoquinones. Homogentisic acid: 质体醌的前体 a precursor of plastoquinones, 高等植物中的生育酚和α-生育酚醌 tocopherols and alpha-tocopherolquinone in higher plants, 绿藻和蓝绿藻。 green algae and blue-green algae. |
已发布 PubMed:d-酪氨酸作为枯草芽孢杆菌的代谢抑制剂。 D-Tyrosine as a metabolic inhibitor of Bacillus subtilis. |
已发布 PubMed:酪氨酸羧基的掺入和d-酪氨酸在黑素生成中的利用。 Incorporation of tyrosine carboxyl groups and utilization of D-tyrosine in melanogenesis. |
已发布 PubMed:脊椎动物皮肤酪氨酸酶对d-酪氨酸利用 Utilization of D-tyrosine by vertebrate skin tyrosinase. |
已发布 PubMed:聚-d-酪氨酸半抗原结合物的免疫原性。 Immunogenicity of hapten conjugates of poly-D-tyrosine. |
已发布 PubMed:迟发型超敏反应中抗原特异性的免疫化学研究。 v。用一价低分子量结合物免疫。 Immunochemical study of antigenic specificity in delayed hypersensitivity. V. Immunization with monovalent low molecular weight conjugates. |
已发布 PubMed:催产素和脱氨基催产素的2-d-酪氨酸-催产素和2-d-酪氨酸-脱氨基催产素的非对映异构体。 2-D-tyrosine-oxytocin and 2-D-tyrosine-deamino-oxytocin diastereoisomers of oxytocin and deamino-oxytocin. |
已发布 PubMed:合成多肽的光学构型与免疫原性之间的关系。 Relation between optical configuration and immunogenicity of synthetic polypeptides. |
已发布 PubMed:[关于o-(n的抗肿瘤活性 [ON THE ANTINEOPLASTIC ACTIVITY OF O--(N,n--双(2-氯乙基)-对氨基苯基)-d N--BIS(2-CHLOROETHYL)-P-AMINOPHENYL)-D,-酪氨酸(phentyrin)]。 -TYROSINE(PHENTYRIN)]. |
已发布 PubMed:酪氨酸对肠膜白球藻p-60的抑制作用及其与培养基中钠和钾含量的关系。 Inhibition of Leuconostoc mesenteroides P-60 by D-tyrosine and its relationship with sodium and potassium content of the medium. |
已发布 PubMed:d-酪氨酸在大鼠中的生长利用。 The utilization of D-tyrosine for growth in the rat. |
已发布 PubMed:d-酪氨酸制备 Preparation of d-tyrosine, 其乙酰基衍生物 its acetyl derivatives, 和d-3 and d-3,4-二羟基苯丙氨酸。 4-dihydroxyphenylalanine. |
已发布 PubMed:溶解度 THE SOLUBILITIES, 表观解离常数 APPARENT DISSOCIATION CONSTANTS, 和二卤代酪氨酸化合物的热力学数据。 AND THERMODYNAMIC DATA OF THE DIHALOGENATED TYROSINE COMPOUNDS. |