5-hydroxytryptophan
tryptophan, 5-hydroxy-, dl- DL-

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  56-69-9 5-羟基l-色氨酸> 98％ 56-69-9 5-Hydroxy L-Tryptophan >98%
  5-羟色氨酸（5-htp） 5-Hydroxytryptophan (5-HTP), 也称为阿西曲普坦（客栈） also known as oxitriptan (INN), 是治疗抑郁症的天然氨基酸和化学前体。 is a naturally occurring amino acid and chemical precursor for the treatment of depression.

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Name: 2-氨基-3-（5-羟基-1h-吲哚-3-基）丙酸 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid CAS号 CAS Number: 56-69-9 3D/INCHI 其他 Other: 114-03-4 echa ECHA einecs Ein INECS - REACH 预注册 前 Pre-Reg: 204-039-6 FDA UNII: 9181P3OI6N nikkaji网站 Nikkaji Web: J61.742C 贝尔斯坦数 Beilstein Number: 0088199 MDL : mfcd00005651 MFCD00005651 XlogP3: -1.20（est） -1.20 (est) 分子量 Molecular Weight: 220.22824000 式 Formula: c11 h12 n2 o3 C11 H12 N2 O3 生物活性总结 BioActivity Summary: 清单 listing 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:food additive   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 调香师和调味师 Perfumer and Flavorist: 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search 已发布 PubMed: 搜索 Search NCBI: 搜索 Search   物理性质 Physical Properties: 出现 Appearance: 白结晶性粉末（est） white crystalline powder (est) 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 熔点 Melting Point: 298.00 to 300.00 °C. @ 760.00 mm 汞 Hg 沸点 Boiling Point: 520.00 to 521.00 °C. @ 760.00 mm 汞 Hg (est) 闪点 Flash Point: 516.00 °F. tcc TCC ( 268.70 °C. ) (est) logp（o / w） logP (o/w): -0.292（est） -0.292 (est) 溶于 Soluble in:   水 water, 1.00e + 04 mg / l @ 25°C（实验） 1.00E+04 mg/L @ 25 °C (exp)   感官特性 Organoleptic Properties: 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: CosIng: 化妆品数据 cosmetic data 化妆品用途 Cosmetic Uses: 皮肤调理 skin conditioning   供应商 Suppliers: 艾迪普 AIDP 5-htp羟色氨酸98％-101％ 5-HTP hydroxytryptophan 98% -101% AuNutra® 行业 Industries 5-HTP BOC Sciences 仅供实验/研究使用。 For experimental / research use only. 5-羟色氨酸> 98％ 5-Hydroxy L-Tryptophan >98% 气味 Odor: characteristic 采用 Use: 5-羟色氨酸（5-htp） 5-Hydroxytryptophan (5-HTP), 也称为阿西曲普坦（客栈） also known as oxitriptan (INN), 是治疗抑郁症的天然氨基酸和化学前体。 is a naturally occurring amino acid and chemical precursor for the treatment of depression. 长沙有机药草 Changsha Organic Herb 5-htp葛根提取物 5-HTP Griffonia simplicifolia Extract Jiangyin Healthway 5-htp 99.0％ 5-HTP 99.0% 新功能食品成分 New functional food ingredients 圣克鲁斯生物技术 Santa Cruz Biotechnology 仅供实验/研究使用。 For experimental / research use only. 5-羟色氨酸≥98％ 5-Hydroxytryptophan ≥98% sds 西安元顺生物技术 Xian Yuensun Biological Technology 5-Hydroxytryptophan, 98%   安全信息 Safety Information: 首选sds SDS : 视图 View   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 腹腔内小鼠 intraperitoneal-老鼠 mouse LD50 200 mg/kg 国民 National 技术 Technical Information 服务 Service. 卷 Vol. AD277-689 皮肤毒性 Dermal Toxicity: 未定 Not determined 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: food additive 推荐使用5-羟基色氨酸剂量 Recommendation for 5-hydroxytryptophan usage levels up to:   不用于香水。 not for fragrance use.   推荐使用5-羟基色氨酸调味剂 Recommendation for 5-hydroxytryptophan flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: Epi系统 EPI System: 视图 View Clinicaltrials.gov ClinicalTrials.gov:search 每日医学 Daily Med:search nlm NLM有害物质数据库 :搜索 Search 辅助引文 AIDS Citations:搜索 Search 癌症引文 Cancer Citations:搜索 Search 毒理学引文 Toxicology Citations:搜索 Search 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search 橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search EPA物质注册服务（tsca TSCA） :56-69-9 EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（srs Srs RS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :144 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data 2-氨基-3-（5-羟基-1h-吲哚-3-基）丙酸 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid chemidplus Chemidplus:0000056699 技术 RTECS:cas71 56-69-9的yn7100000 YN7100000 for cas# 56-69-9   参考资料 References:   2-氨基-3-（5-羟基-1h-吲哚-3-基）丙酸 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI pubchem（cid） Pubchem (cid): 144 pubchem（sid） Pubchem (sid): 134972916   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View KEGG (GenomeNet): C01017 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): HMDB00472 出口关税代码 Export Tariff Code: 2933.90.8000 fda食品添加剂状况清单 FDA Listing of Food Additive Status: 视图 View 医药线 MedlinePlusSupp: 视图 View 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and core 组件 components note 没找到 None Found   潜在用途 Potential Uses: 没找到 None Found   存在（自然 Occurrence (nature, food, 其他） other):note   自然界中找不到 not found in nature   同义词 Synonyms: 2- 氨基 amino-3-(5-hydroxy-1H-indol-3-yl)-丙酸 -propionic acid 2- 氨基 amino-3-(5-hydroxy-1H-indol-3-yl)-丙酸 -propionicacid 2- 氨基 amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid 2- 氨基 amino-3-(5-hydroxy-1H-indol-3-yl)propans�ure 2- 氨基 amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid 2- 氨基 amino-3-(5-hydroxyindol-3-yl)propanoic acid dl- DL-2- 氨基 amino-3-[3-(5-hydroxy吲哚 indole)]propionic acid 5- HTP dl- DL-5- HTP 5- hydroxy tryptophan 5- hydroxy-dl- DL-tryptophan (±)-5- hydroxytryptophan dextro,laevo-5- hydroxytryptophan dl- DL-5- hydroxytryptophan 5- hydroxytryptophan dl- DL-form   阿昔曲坦 oxitriptan dl- DL- pretonine   tryptophan, 5-hydroxy-   tryptophan, 5-hydroxy-, dl- DL- dl- DL- tryptophen, 5-羟基-（9ci） 5-hydroxy- (9CI)   文章 Articles: 已发布 PubMed:5-羟色氨酸与不同脂肪酸结合对胃肠功能的影响 The effects of 5-hydroxytryptophan in combination with different Fatty acids on gastrointestinal functions: 初步实验。 a pilot experiment. 已发布 PubMed:在肠易激综合征中，肠屏障功能的血清素能增强受到损害。 Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome. 已发布 PubMed: 液晶显示器 LC-MS法测定健康志愿者血浆中5-羟色胺邻硫酸盐的含量。 已发布 PubMed:免疫球蛋白和体细胞对脂肪重力分离的影响 The effect of immunoglobulins and somatic cells on the gravity separation of fat, 菌 bacteria, 巴氏杀菌全脂牛奶中的孢子。 and spores in pasteurized whole milk. 已发布 PubMed: 鸡油菌（Cantarellus cibarius cibarius）（黄蘑菇）子实体和体外培养该菌丝体的甲醇提取物中的吲哚化合物含量分析 已发布 PubMed:增强的5-羟色胺会影响比赛结果并增强高强度攻击行为的表达。 Heightened serotonin influences contest outcome and enhances expression of high-intensity aggressive behaviors. 已发布 PubMed:5-羟基色氨酸苷（鳞毛蕨）交配过程中5-羟基色氨酸葡萄糖苷的男性到女性转移。 Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zygaena filipendulae (Lepidoptera). 已发布 PubMed: 参皂苷rb1调节小鼠额叶皮层和小脑中单胺橙花递质的水平，以响应固定压力。 Ginsenoside rb1 modulates level of monoamine neurotransmitters in mice frontal cortex and cerebellum in response to immobilization stress. 已发布 PubMed:全脑单胺的检测和操纵。 Whole brain monoamine detection and manipulation in a stalk-eyed fly. 已发布 PubMed:2的合成 Synthesis of 2,4-二羟基查耳酮衍生物具有潜在的抗抑郁作用。 4-dihydroxychalcone derivatives as potential antidepressant effect. 已发布 PubMed:使用含d-苯丙氨酸食品补充剂 The use of a food supplementation with D-phenylalanine, l-谷氨酰胺和l-5-羟基雷公藤在缓解醇戒断症状。 L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms. 已发布 PubMed:波兰一些烹饪医学上较高的担子菌中的吲哚化合物。 Indole compounds in some culinary-medicinal higher basidiomycetes from Poland. 已发布 PubMed:尽管弓状npy表达增加，但是5-羟基-1-色氨酸抑制了大鼠的食物摄入。 5-hydroxy-L-tryptophan Suppressed Food Intake in Rats Despite an Increase in the Arcuate NPY Expression. 已发布 PubMed:葛根对大鼠男性性行为的影响 Influence of Griffonia simplicifolia on male sexual behavior in rats: 行为和橙花化学研究。 behavioral and neurochemical study. 已发布 PubMed:液体 Liquid 色谱法 chromatography on a 单片 monolithic 柱 column 微流体 microfluidic 芯片 chip 耦合的 coupled with "三吨 three-T" 样品 sample 注射 injection 模式 mode and 安培 ampero公制 metric 检测 detection. 已发布 PubMed:5-羟基色氨酸通过抑制 类成纤维细胞上的反应性物种（rs）和核因子-kappab（nf-kappab）活化来抑制叔丁基氢过氧化物（t-bhp）诱导的氧化损伤。 5-Hydroxytrytophan inhibits tert-butylhydroperoxide (t-BHP)-induced oxidative damage via the suppression of reactive species (RS) and nuclear factor-kappaB (NF-kappaB) activation on human fibroblast. 已发布 PubMed:短剑对雌性大鼠的性行为产生负面影响。 Griffonia simplicifolia negatively affects sexual behavior in female rats. 已发布 PubMed:儿童睡眠障碍。 Sleep disorders in children. 已发布 PubMed:周围肽yy通过有意识的小鼠中的y2受体抑制结肠结肠运动功能 Peripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious mice. 已发布 PubMed:进餐 Meal ingestion, 氨基酸和脑橙花递质 amino acids and brain neurotransmitters: 蛋白质来源对血清素和儿茶酚胺合成速率的影响 effects of dietary protein source on serotonin and catecholamine synthesis rates. 已发布 PubMed:使用化学和代谢谱分析方法表征普-茶。 Characterization of pu-erh tea using chemical and metabolic profiling approaches. 已发布 PubMed:慢性自愿摄入乙醇会使c57bl / 6j小鼠中的5-ht（1a）自身受体超敏。 Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. 已发布 PubMed:重复施用新鲜大蒜可增加大鼠记忆力。 Repeated administration of fresh garlic increases memory retention in rats. 已发布 PubMed:血清素药物 Serotonergic drugs : 对食欲的影响和用于肥胖症的治疗。 effects on appetite expression and use for the treatment of obesity. 已发布 PubMed:血清素耗竭在新奇诱发的吞咽测试中的抗焦虑作用。 Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test. 已发布 PubMed:色氨酸增强断奶仔猪的生长素释放肽表达和分泌，与食物摄入量增加和体重增加有关。 Tryptophan enhances ghrelin expression and secretion associated with increased food intake and weight gain in weanling pigs. 已发布 PubMed:饮酒量变化 Alterations in alcohol consumption, 停药发作 withdrawal seizures, 芬特明和5-羟基-1-色氨酸处理的大鼠体内的单胺传递和单胺传递。 and monoamine transmission in rats treated with phentermine and 5-hydroxy-L-tryptophan. 已发布 PubMed: 证据表明，血清素能系统参与控制了coturnix Coturnix japonica（galliformes）的摄食行为 : aves）。 Aves). 已发布 PubMed:对血清素能系统在控制喂养行为中的作用的重新评估。 A reassessment of the role of serotonergic system in the control of feeding behavior. 已发布 PubMed:5-羟基-1-色氨酸安全性。 Safety of 5-hydroxy-L-tryptophan. 已发布 PubMed:5-羟基-1-色氨酸抑制食物缺乏和压力大的大鼠的食物摄入。 5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats. 已发布 PubMed:独特的中央色氨酸羟化酶同工型。 A unique central tryptophan hydroxylase isoform. 已发布 PubMed:全身性5-羟基-1-色氨酸下调大鼠弓形cartRNA水平。 Systemic 5-hydroxy-L-tryptophan down-regulates the arcuate CART mRNA level in rats. 已发布 PubMed:使用常规色谱和圆二色性检测器对旋光性化合物进行分析 Analysis of optically active compounds using conventional chromatography with a circular dichroism detector. 已发布 PubMed:侏儒症和低胰岛素样生长因子-1，归因于通过喂食橙花递质前体和h4-生物蝶呤拯救的pts //小鼠中的多巴胺消耗。 Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin. 已发布 PubMed:成 的步态和平衡功能障碍。 Gait and Balance Dysfunction in Adults. 已发布 PubMed:羟色胺和5-羟色胺1-a受体在乙醇治疗的大鼠无法适应重复的应激时间表中发挥作用。 Serotonin and serotonin 1-A receptors in the failure of ethanol-treated rats to adapt to a repeated stress schedule. 已发布 PubMed:用于控制体重的功能性食品。 A functional food product for the management of weight. 已发布 PubMed:断断续续的 Intermittent, 尽管大量降低了大脑的血清5-羟色胺，但长期给大鼠服用芬氟拉明会反复抑制食物摄入。 chronic fenfluramine administration to rats repeatedly suppresses food intake despite substantial brain serotonin reductions. 已发布 PubMed:肽和蛋白质中游离色氨酸和色氨酸残基的氧化。 Oxidation of Free Tryptophan and Tryptophan Residues in Peptides and Proteins. 已发布 PubMed:γ射线照射的蛋清中羟色氨酸异构体的测定 Determination of hydroxytryptophan isomers in gamma-irradiated egg white, 鸡肉 chicken meat, 和虾。 and shrimps. 已发布 PubMed:5-羟基色氨酸对非胰岛素依赖型糖尿病患者能量摄入和大量营养素选择的影响 Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients. 已发布 PubMed:5ht1a受体拮抗剂可在喂养的小鼠模型中增强氟西汀的功能活性。 5HT1A receptor antagonists enhance the functional activity of fluoxetine in a mouse model of feeding. 已发布 PubMed:突触前和突触后5-ht1a受体的阻断不会改变氟西汀或5-羟色氨酸对大鼠乙醇和食物摄入的影响。 Blockade of pre- and post-synaptic 5-HT1A receptors does not modify the effect of fluoxetine or 5-hydroxytryptophan on ethanol and food intake in rats. 已发布 PubMed:剥夺对刘易斯和shr大鼠中脑5-ht1a自身受体的影响 Effects of food deprivation on midbrain 5-HT1A autoreceptors in Lewis and SHR rats. 已发布 PubMed:食堂饮食引起的肥胖症的体重增加和最终肥胖与中枢5-羟色胺能性色调无关。 The weight gain and ultimate adiposity in cafeteria diet-induced obesity is unrelated to the central serotoninergic tonus. 已发布 PubMed:1192u90在动物试验中预测抗精神病药的功效 1192U90 in animal tests that predict antipsychotic efficacy, 焦虑症 anxiolysis, 和锥体束外的副作用。 and extrapyramidal side effects. 已发布 PubMed:镰刀菌毒素的橙花药理研究--ii Neuropharmacological studies on Fusarium toxins--II: 总毒素提取物羟孢菌 oxysporum。 已发布 PubMed:下丘脑脑橙花递质的变化与进食行为有关。 Changes in brain neurotransmitters in hypothalamus related to feeding behavior in LEC rat. 已发布 PubMed:食物限制会降低下丘脑的5-羟色胺及其合成速率。 Food restriction decreases serotonin and its synthesis rate in the hypothalamus. 已发布 PubMed:i.c.v.的效力注射5 Effect of the i.c.v. injection of 5,7-二羟基色胺对优势和顺从鸽子的侵略行为（哥伦巴利维亚）。 7-di-hydroxytryptamine on the aggressive behavior of dominant and submissive pigeons (Columba livia). 已发布 PubMed:亚慢性和长期暴露于5-羟色氨酸（5-htp）对营养不良的优势和柔弱鸽子（哥伦巴利维亚）的食物竞争所引起的攻击行为的影响。 Effect of subchronic and chronic exposure to 5-hydroxytryptophan (5-HTP) on the aggressive behavior induced by food competition in undernourished dominant and submissive pigeons (Columba livia). 已发布 PubMed:合成 Synthesis of 多巴胺 dopamine and 5-HT in 解剖的 anatomical 地区 regions of the rat's 脑 brain is 不受影响 unaffected by by 持续 sustained 输液 infusion of 安非尼 amperozide. 已发布 PubMed:连续进餐后，脑中色氨酸浓度和血清素的合成仍然对食物的摄入有反应。 Brain tryptophan concentrations and serotonin synthesis remain responsive to food consumption after the ingestion of sequential meals. 已发布 PubMed:5-羟色胺抑制大鼠进食的血清素能机制。 Serotonergic mechanisms involved in the suppression of feeding by 5-HTP in rats. 已发布 PubMed:嗜酸性粒细胞增多症-肌痛综合征相关疾病，与暴露于1-5-羟色氨酸有关。 An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan. 已发布 PubMed:适应反复约束后，大脑区域性5-羟色胺合成。 Brain regional serotonin synthesis following adaptation to repeated restraint. 已发布 PubMed:[内源性 样物质系统参与调节软体动物剑叶的食性和保护行为]。 [The participation of the endogenous opioid system in regulating the feeding and protective behaviors of the mollusk Lymnaea stagnalis]. 已发布 PubMed:放牧被内生菌感染的高羊茅放牧后的褪黑激素和松果体中的橙花化学物质 Melatonin and pineal neurochemicals in steers grazed on endophyte-infected tall fescue: 甲氧氯普胺的作用。 effects of metoclopramide. 已发布 PubMed:替丁对5-htp和右芬氟拉明诱发的大鼠吞咽的影响。 Effects of tianeptine on 5-HTP- and dextrofenfluramine-induced hypophagia in the rat. 已发布 PubMed:ly248686 LY248686, 一种新的5-羟色胺和去甲肾上腺素摄取抑制剂。 a new inhibitor of serotonin and norepinephrine uptake. 已发布 PubMed:胺前体对雄性大鼠食物摄入的影响。 Effects of monoamine precursors on food intake in male rats. 已发布 PubMed:5-羟色氨酸治疗的肥胖成年受试者的饮食行为和饮食习惯。 Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. 已发布 PubMed:[在调节动机和情绪状态的药理暴露期间腹侧下丘脑的橙花元活动]。 [The neuronal activity of the ventromedial hypothalamus during pharmacological exposures that modulate motivational and emotional states]. 已发布 PubMed:5-羟-1-色氨酸和2-氨基乙基异硫脲溴化氢溴酸盐在致死性照射的大鼠中对糖酵解的保护作用。 Protection to glycolysis by a combination of 5-hydroxy-L-tryptophan and 2-aminoethylisothiuronium bromide hydrobromide in lethally irradiated rats. 已发布 PubMed:色氨酸在大鼠中的致热作用独立于5-ht介导。 Thermogenic actions of tryptophan in the rat are mediated independently of 5-HT. 已发布 PubMed:矮山羊的食物摄入和小酸模/羊酸模/红酸模动力。血清素受体激动剂和拮抗剂的作用。 Food intake and rumen motility in dwarf goats. Effects of some serotonin receptor agonists and antagonists. 已发布 PubMed:促肾上腺皮质激素释放因子（crf）与5-羟色胺（5-ht）及其相关化合物的生热和厌食作用有关。 Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds. 已发布 PubMed:拮抗剂的效力表明5-ht1c受体介导1-3（氯苯基）哌嗪诱导的吞咽不足。 Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia. 已发布 PubMed:下丘脑单胺和偏好醇的aa和避免醇的ana大鼠的食物摄入。 Hypothalamic monoamines and food intake in alcohol-preferring AA and alcohol-avoiding ANA rats. 已发布 PubMed:5-羟色氨酸对大鼠进近和回避行为的差异作用。 Differential effect of 5-hydroxytryptophan on approach and avoidance behavior in rats. 已发布 PubMed:量对纹状体中合成速率及多巴胺和5-羟色胺释放的影响 Effect of precursor loading on the synthesis rate and release of dopamine and serotonin in the striatum: 在清醒大鼠中进行微透析研究。 a microdialysis study in conscious rats. 已发布 PubMed:5-羟色氨酸对肥胖成 受试者饮食行为和饮食习惯的影响 Effects of 5-hydroxytryptophan on eating behavior and adherence to dietary prescriptions in obese adult subjects. 已发布 PubMed:在被内生菌感染的羊草上放牧的ste牛中进行橙花内分泌测量。 Neuroendocrine measurements in steers grazed on endophyte-infected fescue. 已发布 PubMed:熟食食品的3-氨基-1-甲基-5h-吡啶酮对 脑芳香族l-氨基酸脱羧酶的抑制作用[4] Inhibition of human brain aromatic L-amino acid decarboxylase by cooked food-derived 3-amino-1-methyl-5H-pyrido[4,3-b]吲哚（trp-p-2）和其他杂环胺。 3-b]indole (Trp-P-2) and other heterocyclic amines. 已发布 PubMed:血清素摄取阻滞剂和5-羟色氨酸对自愿摄入乙醇的影响 Effects of serotonin uptake blockers and of 5-hydroxytryptophan on the voluntary consumption of ethanol, ucha和uchb大鼠提供水和固体食物。 water and solid food by UChA and UChB rats. 已发布 PubMed:5-羟色胺和酮色林对优势和顺从性鸽子食物竞争引起的侵略性反应的影响 Effect of 5-HTP and ketanserine on the aggressive reaction induced by food competition in dominant and submissive pigeons (Columba livia). 已发布 PubMed:抵抗性抑郁症的治疗。各种生物治疗功效的综述 Treatment of resistant depression. Review on the efficacy of various biological treatments, 特别是对循环抗抑郁药有抵抗力的严重抑郁症。 specifically in major depression resistant to cyclic antidepressants. 已发布 PubMed:血清素分析 Analysis of serotonin, 多巴胺及其在尾状壳中的代谢产物 dopamine and their metabolites in the caudate putamen, 常温和to性皮肤的chi上眼核和中缝核 the suprachiasmatic nucleus and the median raphe nucleus of euthermic and torpid deermice, 躁狂症 maniculatus。 已发布 PubMed: 摄入苜蓿和果园草（dactylis 肾小球 glomerata l。）干草对绵羊阿波玛索-十二指肠交界处前胃运动和消化流的影响。 已发布 PubMed:自发性高血压大鼠中的5-羟色氨酸和卡比多巴。 5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats. 已发布 PubMed:抗氧化剂-色氨酸和5-羟色氨酸抑制自由基过程。 Inhibition of free radical processes by antioxidants--tryptophan and 5-hydroxytryptophan. 已发布 PubMed:血清素激动剂和拮抗剂对准吗啡戒断的治疗 Modification of quasi-morphine withdrawal with serotonin agonists and antagonists: 血清素在 戒断表达中的作用的证据。 evidence for a role of serotonin in the expression of opiate withdrawal. 已发布 PubMed:口服5-羟色氨酸对肥胖成年女性受试者摄食行为的影响。 The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. 已发布 PubMed:类 激动剂或纳洛酮与5-htp对食物不足大鼠进食行为的相互作用。 Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived rats. 已发布 PubMed:酮色林的拮抗作用是对奎巴嗪的行为作用而不是对l-5-羟基色氨酸影响。 Antagonism by ketanserin of the behavioral effects of quipazine but not l-5-hydroxytryptophan in squirrel monkeys. 已发布 PubMed:1- [2-（4-氨基苯基）乙基] -4-（3-三氟甲基苯基）哌嗪（ly 165163）在中心5-ht受体上的激动作用的橙花化学和行为证据。 Neurochemical and behavioural evidence for an agonist action of 1-[2-(4-aminophenyl)ethyl]-4-(3-trifluoromethylphenyl)piperazine (LY 165163) at central 5-HT receptors. 已发布 PubMed:慢性利血平后大鼠体内增强的5-羟色氨酸诱导的反应抑制。 Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine. 已发布 PubMed:[情绪应激对狗空肠电活动的影响]。 [Effect of emotional stress on the electrical activity of the jejunum in the dog]. 已发布 PubMed:5-羟色氨酸和西沙必利可刺激狗的空肠动力和食糜的转运。 5-Hydroxytryptophan and cisapride stimulate propulsive jejunal motility and transit of chyme in dogs. 已发布 PubMed:分解5-htp和芬氟拉明的厌食作用。 Dissociation of the anorectic actions of 5-HTP and fenfluramine. 已发布 PubMed:进餐对血浆和脑氨基酸影响 Effect of mealing on plasma and brain amino acid, 口服阿斯巴甜后大鼠体内的脑和脑单胺含量升高。 and brain monoamine in rats after oral aspartame. 已发布 PubMed:电击探针冲突程序。对苯二氮卓类药物有反应的新方法 The shock probe conflict procedure. A new assay responsive to benzodiazepines, 巴比妥类药物和相关化合物。 barbiturates and related compounds. 已发布 PubMed:用5-羟色氨酸和脱羧酶抑制剂治疗缺氧性肌阵挛的病理结果。 Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor. 已发布 PubMed:血清素受体激动剂和拮抗剂对松鼠猴子进度控制行为的影响。 Effects of serotonin receptor agonists and antagonists on schedule-controlled behavior of squirrel monkeys. 已发布 PubMed:使用对β受体激动剂敏感的四种心理药理试验比较盐酸克仑特罗对映体。 Comparison of clenbuterol enantiomers using four psychopharmacological tests sensitive to beta-agonists. 已发布 PubMed:麻风的营养方面。 Nutritional aspects of leprosy. 已发布 PubMed:酮色林对慢性5-羟色胺（5-ht2）受体阻滞的抗高血压作用。 Antihypertensive effects of chronic 5-hydroxytryptamine (5-HT2) receptor blockade with ketanserin in the spontaneously hypertensive rat. 已发布 PubMed:多香果和脑5-羟色胺 Anorexia and brain serotonin: 5-羟色胺耗竭性病变大鼠对芬氟拉明和喹嗪的耐受性的研究 development of tolerance to the effects of fenfluramine and quipazine in rats with serotonin-depleting lesions. 已发布 PubMed:在抑郁症动物模型中用曲唑酮长期抗抑郁治疗后的突触后血清素能阻滞。 Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. 已发布 PubMed:l-5 htp在处理ind下可用。 L-5 HTP available under treatment IND. 已发布 PubMed: 液晶显示器 LCEC监测与睡眠和进食有关的大鼠脑脊液中的5-羟基吲哚化合物。 已发布 PubMed:氟西汀和l-5-羟基色氨酸联合抑制大鼠饮酒。 Suppression of milk drinking by the combination of fluoxetine and L-5-hydroxytryptophan in rats. 已发布 PubMed:美拉德型羰基胺的体内反应及其生理作用。 Maillard type carbonyl-amine reactions in vivo and their physiological effects. 已发布 PubMed:抑郁动物模型中的突触前和突触后血清素能操纵。 Pre- and postsynaptic serotonergic manipulations in an animal model of depression. 已发布 PubMed:偏头痛 Migraine headache: 体征和症状 signs and symptoms, 生物化学 biochemistry, 和当前的疗法。 and current therapy. 已发布 PubMed:长期饮酒后大鼠脑区域中的单胺代谢。 Monoamine metabolism in rat brain regions following long term alcohol treatment. 已发布 PubMed:血清素能对食物摄入的影响 Serotonergic influences on food intake: 5-羟色氨酸对饥饿和自由进食大鼠进食行为参数的影响 effect of 5-hydroxytryptophan on parameters of feeding behaviour in deprived and free-feeding rats. 已发布 PubMed:高效液相色谱法测定食物不足大鼠离散脑区域中的生物胺。 HPLC determination of biogenic amines in discrete brain areas in food deprived rats. 已发布 PubMed:遗传性营养不良的大鼠大脑皮质中的na + -k + -atpase活性 Na+-K+-ATPase activity in the brain cortex of rats ontogenetically malnourished, 并用5-羟色胺前体治疗。 and treated with serotonin precursors. 已发布 PubMed:禁食期对下丘脑外侧区5-羟色胺合成的影响 Effects of various periods of food deprivation on serotonin synthesis in the lateral hypothalamus. 已发布 PubMed:对氯一丁 para-Chloro-D, L-苯丙氨酸在雌性大鼠中诱导了杀菌行为。 L-phenylalanine induced filicidal behavior in the female rat. 已发布 PubMed:产前氟烷的行为和橙花化学作用。 Behavioral and neurochemical effects of prenatal halothane. 已发布 PubMed:[在脑5-羟色胺和去甲肾上腺素水平的定向变化的条件下，大鼠情绪增强强化训练的特征]。 [Characteristics of rat training on emotionally varied reinforcement under conditions of an oriented change in the level of brain serotonin and noradrenaline]. 已发布 PubMed:3-羧基-10的食欲刺激活性 Appetite stimulant activity of 3-carboxy-10,11-二氢环庚庚定。 11-dihydrocyproheptadine. 已发布 PubMed:礼来公司110140的影响 Effects of Lilly 110140, 5-羟色胺摄取的特异性抑制剂 a specific inhibitor of 5-hydroxytryptamine uptake, 食物摄入和5-羟色氨酸引起的多香果。血清素能抑制进食的证据。 on food intake and on 5-hydroxytryptophan-induced anorexia. Evidence for serotoninergic inhibition of feeding. 已发布 PubMed:食用食物后大脑血清素和5-hiaa急剧减少 Acute reduction of brain serotonin and 5-HIAA following food consumption: 与血清色氨酸与竞争氨基酸总和之比的相关性。 correlation with the ratio of serum tryptophan to the sum of competing amino acids. 已发布 PubMed:5-羟色氨酸对食物摄入以及苯丙胺和芬氟拉明的厌食作用的影响。 The effect of 5-hydroxytryptophan on food intake and on the anorexic action of amphetamine and fenfluramine. 已发布 PubMed:对氯苯丙氨酸和5-羟基色氨酸对大鼠醇摄入的影响 Effects of para-chlorophenylalanine and 5-hydroxytryptophan on alcohol intake in the rat. 已发布 PubMed:dl-对氯苯丙氨酸对蔗糖偏爱和摄取的影响 Effects of dl-para-chlorophenylalanine on sucrose preference and intake: 5-羟色氨酸和6-甲氧基1逆转 reversal by 5-hydroxytryptophan and 6-methoxy 1,2,3,4,-四氢-β-咔啉。 -tetrahydro-beta-carboline. 已发布 PubMed:dl-对氯苯丙氨酸处理的大鼠中5-羟色氨酸自我选择。 Self-selection of 5-hydroxytryptophan in dl-para-chlorophenylalanine treated rats. 已发布 PubMed:未麻醉猴子的胃窦和虫的收缩活性。 Contractile activity of gastric antrum and taenia coli in the unanesthetized monkey. 已发布 PubMed:各种刺激物对 和脂肪对胃动力的影响 Effect of bile and fat on gastric motility under the influence of various stimulants. 已发布 PubMed:[5-羟色氨酸（5-羟色胺前体）对家兔食物摄取条件反射的影响]。 [THE EFFECT OF 5-HYDROXYTRYPTOPHEN (SEROTONIN PRECURSOR) ON FOOD-PROCURING CONDITIONED REFLEXES IN RABBITS].

笔记 Notes: 从色氨酸生物合成5-羟色胺的直接前体。它用作抗癫痫药和抗抑郁药。 the immediate precursor in the biosynthesis of serotonin from tryptophan. it is used as an antiepileptic and antidepressant.