dextro,laevo-threonine
dl-2-氨基-3-羟基丁酸 DL-2-amino-3-hydroxybutanoic acid

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    t0229 dl-苏氨酸> 98.0%(t) T0229 DL-Threonine >98.0%(T)
Name:2-氨基-3-羟基丁酸 2-amino-3-hydroxybutanoic acid
CAS号 CAS Number: 80-68-2Picture of molecule3D/INCHI
其他 Other:1187422-62-3
ECHA einecs Ein INec ECS - REACH 预注册 Pre-Reg:201-300-6
FDA UNII:TFM6DU5S6A
nikkaji网站 Nikkaji Web:J1.252A
贝尔斯坦数 Beilstein Number:1721647
MDL :mfcd00063722 MFCD00063722
XlogP3:-2.90(est) -2.90 (est)
分子量 Molecular Weight:119.12033000
式 Formula:c4 h9 n o3 C4 H9 N O3
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
efsa / jecfa评论 EFSA/JECFA Comments:
将注册名称更改为dl-苏氨酸(外消旋物)(efsa Register name to be changed to DL-threonine (racemate) (EFSA, 2006b) 2006b)
类别 Category:flavoring agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
Flavis号码 FLAVIS Number:17.021(旧) 17.021 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:17.021 dl-苏氨酸 17.021 DL-threonine
 
物理性质 Physical Properties:
出现 Appearance:白粉末(est) white powder (est)
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 230.00 to 244.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 345.80 °C. @ 760.00 mm 汞 Hg (est)
蒸汽压力 Vapor Pressure:0.000003 毫米汞柱 mm汞 Hg @ 25.00 °C. (est)
闪点 Flash Point: 325.00 °F. tcc TCC ( 162.78 °C. )
logp(o / w) logP (o/w): -1.136(est) -1.136 (est)
溶于 Soluble in:
 alcohol
 水 water, 2.79e+005 mg/L @ 25 &deg °C (est)
 水 water, 2.01e + 05 mg / l @ 25°C(实验值) 2.01E+05 mg/L @ 25 °C (exp)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: 抗静电剂 antistatic agents
头发调理 hair conditioning
直发剂 hair straightening agents
发质剂 hair waving agents
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
h-dl-thr-oh 99% H-DL-Thr-OH 99%
Glentham Life Sciences
苏氨酸 DL-Threonine
OQEMA
Threonine
Penta International
苏氨酸 DL-Threonine
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
苏氨酸 DL-Threonine
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
dl-苏氨酸≥90%(tlc) DL-Threonine ≥90% (TLC)
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
苏氨酸> 98.0%(t) DL-Threonine >98.0%(T)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
欧洲信息 European information :
最重要的危害 Most important hazard(s):
无-找不到。 None - None found.
S 02 - 保持 Keep out of the 达到 reach of 孩子们 children.
S 24/25 - 避免 Avoid contact with skin 皮 and 眼睛 eyes.
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
flavoring agents
dextro推荐 Recommendation for dextro,Laevo-苏氨酸使用水平高达 laevo-threonine usage levels up to:
 不用于香水。 not for fragrance use.
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 0.12(微克/ 均/天) 0.12 (μg/capita/day)
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): 49000(微克/ /天) 49000 (μg/person/day)
关注点 Threshold of Concern:1800(微克/ /天) 1800 (μg/person/day)
结构类 Structure Class: I
 
根据委员会法规ec EC号的食品类别。 1565/2000(ec , 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the Industry the "正常 normal" use is 定义的 de精细 fined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 de精细 fined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (efsa EFSA, 2002i)。 2002i).
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm
 平均 average 用法 usage mg/kg kg最大 maximum 用法 usage mg/kg kg
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): --
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): --
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): --
加工水果(04.1) Processed fruit (04.1): --
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): --
糖果(05.0) Confectionery (05.0): --
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): --
烘焙用具(07.0) Bakery wares (07.0): --
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): --
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : --
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): --
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): --
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): --
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): --
不含醇 Non-alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): 150.00000-
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): --
即食美味(15.0) Ready-to-eat savouries (15.0): --
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

化学组中的氨基酸34调味组评估26 Amino acids from chemical group 34 Flavouring Group Evaluation 26, 修订1-食品添加剂小组的科学意见 Revision 1 - Scientific opinion of the Panel on Food Additives, 调味料 Flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC)
视图 View page or 视图 View pdf

调味组评估29(fge29)[1]-优先列表中的物质 Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: 化学组31中的乙烯基苯-食品添加剂专家组的科学意见 Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, 调味料 Flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in 联系 Contact with Food (afc AFC)
视图 View page or 视图 View pdf

调味组评估79 Flavouring Group Evaluation 79, (ge FGE.79)[1] - 考虑 Consideration of amino acids and 有关 related 物质 substances 已评估 evaluated by by Jec ECFA (63rd 会议 meeting) 结构上 structurally 有关 related to amino acids from chemical group 34 已评估 evaluated by by efsa EFSA in ge FGE.26Rev1 (2008)
视图 View page or 视图 View pdf

efsa EFSA关于授权酸盐风险评估的科学报告 , 酚类 phenols or alcohols for use in food contact 材料 materials [1]
视图 View page or 视图 View pdf

调味品组评价的科学见解49 Scientific Opinion on Flavouring Group Evaluation 49, 版本1(fge.49rev1) Revision 1 (FGE.49Rev1): 黄嘌呤 xanthine 生物碱 alkaloids from the 优先 priority list
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search
EPA物质注册服务(tsca TSCA) :80-68-2
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :205
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
2-氨基-3-羟基丁酸 2-amino-3-hydroxybutanoic acid
chemidplus Chemidplus:0000080682
 
参考资料 References:
 2-氨基-3-羟基丁酸 2-amino-3-hydroxybutanoic acid
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:80-68-2
pubchem(cid) Pubchem (cid):205
pubchem(sid) Pubchem (sid):135025753
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
出口关税代码 Export Tariff Code:2922.49.4050
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
 抗静电剂 antistatic agents
 
存在(自然 Occurrence (nature, food, 其他) other):note
 天然产物 found in nature
 
同义词 Synonyms:
2-amino-3-hydroxybutanoic acid
dextro,laevo-2-amino-3-hydroxybutanoic acid
dl- DL-2-amino-3-hydroxybutanoic acid
(±)-2-amino-3-hydroxybutyric acid
 H-dl- DL-Thr-OH
 threonin
 threonine
(±)-threonine
allo-dl- DL-threonine
dl- DL-threonine
dl- DL-allothreonine
dl- DL-allo-threonine
 threonine, dl- DL-
 

文章 Articles:

已发布 PubMed:通过减弱谷氨酸棒状杆菌的细胞壁并增加细胞质膜的流动性来提高其转化效率。 Improving the electro-transformation efficiency of Corynebacterium glutamicum by weakening its cell wall and increasing the cytoplasmic membrane fluidity.
阶段 J-Stage:日粮低水平的苏氨酸和赖氨酸对猪肌肉中肌内脂肪堆积的影响 Effects of Dietary Low Level of Threonine and Lysine on the Accumulation of Intramuscular Fat in Porcine Muscle
已发布 PubMed:矫正右旋大动脉的患者将心件心室辅助设备放置在患者体内 HeartWare Ventricular Assist Device Placement in a Patient With Corrected Dextro-Transposition of Great Arteries: 病例报告及其临床挑战。 A Case Report and Its Clinical Challenges.
已发布 PubMed:电穿孔法转化副猪魏氏杆菌dx的质粒。 Plasmid transformation of Weissella paramesenteroides DX by electroporation.
已发布 PubMed:患病率 Prevalence, 黎巴嫩2型糖尿病的相关性和管理 correlates and management of type 2 diabetes mellitus in Lebanon: 一项基于全国 口的研究的发现。 findings from a national population-based study.
已发布 PubMed:评估手性开关 Assessing the chiral switch: 批准和使用单一对映体药物 approval and use of single-enantiomer drugs, 2001年至2011年。 2001 to 2011.
已发布 PubMed:吲哚胺2的选择性抑制剂的鉴定 Identification of selective inhibitors of indoleamine 2,3-双加氧酶2。 3-dioxygenase 2.
已发布 PubMed:右旋哌醋甲酯缓释胶囊用于注意缺陷多动障碍。 Dexmethylphenidate extended-release capsules for attention deficit hyperactivity disorder.
已发布 PubMed:鉴定和估算含有阿托品和/或丝胺的原料和成品中的左旋异构体。 Identification and estimation of the levo isomer in raw materials and finished products containing atropine and/or hyoscyamine.
已发布 PubMed:[明智地使用厌食药]。 [Judicious use of anorectics].
已发布 PubMed:三碘甲状腺素的血脑运输在老年大鼠中减少。 Blood-brain transport of triiodothyronine is reduced in aged rats.
已发布 PubMed:通过控制中央5-羟色胺减少食物摄入。当前的实验结果。 Reduction of food intake by manipulation of central serotonin. Current experimental results.
已发布 PubMed:改善完整乳球菌亚种的电穿孔效率。在特定培养基中生长的乳酸菌细胞。 Improved electroporation efficiency of intact Lactococcus lactis subsp. lactis cells grown in defined media.
已发布 PubMed:口服自我给药的n-allylnormetazocine(skf-10 Oral self-administration of N-allylnormetazocine (SKF-10,047)恒河猴中的立体异构体 047) stereoisomers in rhesus monkeys: 苯环利定自我给药和撤药时进行替代。 substitution during phencyclidine self-administration and withdrawal.
已发布 PubMed:下丘脑内侧5-羟色胺 Medial hypothalamic serotonin: 对剥夺和去甲肾上腺素引起的进食的影响。 effects on deprivation and norepinephrine-induced eating.
已发布 PubMed: ly150720(匹那多 picenadol)的作用 , 新型的混合作用 类药物 a novel mixed-action opioid, 在松鼠猴中按时间表控制的响应。 on schedule-controlled responding in the squirrel monkey.
已发布 PubMed:辣椒中黑小麦的化学和营养评估 [Chemical and nutritional evaluation of triticale (Secale sp.) cultivated in Chile].
已发布 PubMed:氯胺酮立体异构体在苯环利定训练的大鼠中的判别刺激特性。 Discriminative stimulus properties of ketamine stereoisomers in phencyclidine-trained rats.
已发布 PubMed:[关于小鸡的蛋氨酸-苏氨酸失衡的研究]。 [Studies on the methionine-threonine imbalance in chicks].
已发布 PubMed:厌食剂量右旋苯丙胺对腹侧下丘脑肥大大鼠的影响。 The effects of anorexic doses of dextro-amphetamine on the ventromedial-hypothalamic hyperphagic rat.
已发布 PubMed:同步记录不同药物作用下大鼠食物和液体的摄取及运动能力 [SIMULTANEOUS RECORDING OF FOOD AND LIQUID UPTAKE AND MOTOR ACTIVITY IN RATS UNDER THE EFFECT OF DIFFERENT DRUGS].
已发布 PubMed:d-苯丙胺-氯丙嗪对食品强化手术的拮抗作用。 d-Amphetamine-chlorpromazine antagonism in a food reinforced operant.
 
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