类别 Category:antioxidants and preservatives
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
化验 Assay: | 95.00至100.00 95.00 to 100.00
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食品化学品法典列表 Food Chemicals Codex Listed: | No |
熔点 Melting Point: | 118.00 °C. @ 760.00 mm 汞 Hg
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沸点 Boiling Point: | 298.00 °C. @ 760.00 mm 汞 Hg
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蒸汽压力 Vapor Pressure: | 0.001000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) |
闪点 Flash Point: | 248.00 °F. tcc TCC ( 120.00 °C. )
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logp(o / w) logP (o/w): | 2.470 |
溶于 Soluble in: |
| alcohol | | 水 water, 1894 mg/L @ 25 &deg °C (est) | | 水 water, 885 mg / l @ 25°C(实验) 885 mg/L @ 25 °C (exp) |
感官特性 Organoleptic Properties:
气味强度 Odor Strength:低 low |
气味描述 Odor Description:at 100.00 %. 轻度 mild 酚醛的 phenolic |
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
艰巨的 Acme-Hardesty |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
气味 Odor: characteristic 采用 Use: 化妆品和个 护理中使用的抗菌防腐剂。 Antimicrobial Preservative Used in Cosmetics and Personal Care. |
BOC Sciences |
仅供实验/研究使用。 For experimental / research use only. |
Ethylparaben
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库姆波 Coompo |
仅供实验/研究使用。 For experimental / research use only. |
Ethylparaben from 植物 Plants ≥96%
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Emd 微孔 Millipore |
仅供实验/研究使用。 For experimental / research use only. |
4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE
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外合成 ExtraSynthese |
仅供实验/研究使用。 For experimental / research use only. |
4-羟基苯甲酸乙酯(hplc)≥99% Ethyl-4-hydroxybenzoate (HPLC) ≥99%
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食品化学国际 Foodchem International |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
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Glentham Life Sciences |
4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE
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霍尔星 HallStar |
cosept(tm)e CoSept(tm) E
气味 Odor: characteristic 采用 Use: cosept e对所有对羟基苯甲酸酯表现出的革兰氏阳性细菌具有良好的性能,并且对ph值范围具有相同的限制(仅酸性) CoSept E provides the good performance against Gram positive bacteria exhibited by all the parabens and has the same limitations regarding pH range (acidic only), 系统相容性(避免高含量的乙氧基化物)和水溶性(有限)。对羟基苯甲酸乙酯已与对羟基苯甲酸丙酯联合用于口服制剂,以控制发酵作用。可以单独使用 system compatibility (avoid high levels of ethoxylates) and water solubility (limited). Ethylparaben has been used in combination with Propylparaben in oral preparations for controlling fermentative action. It can be used alone, 但通常以0.10到0.25%的水平与其他前药一起用作防腐剂系统的抗真菌部分。 but is generally used at 0.10 to 0.25% levels with other CoSepts as the antifungal portion of the preservative system. |
井上香水 Inoue Perfumery |
4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE
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金永生物技术 Kingyoung Bio Technical |
Ethylparaben
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牛皮纸化学 Kraft Chemical |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
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南京建城化工 Nanjing Jiancheng Chemical |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
气味 Odor: characteristic 采用 Use: 对羟基苯甲酸乙酯主要用作化妆品中的防腐剂 Ethylparaben is mainly used as antiseptics in cosmetics, 食品和药品。它也可用作饲料防腐剂和细菌防腐剂。 food and medicine. It is also can be used as feed preservatives and antiseptic for bacteria. |
Penta International |
对羟基苯甲酸乙酯nf级 ETHYL-P-HYDROXYBENZOATE NF GRADE
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Penta International |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
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圣克鲁斯生物技术 Santa Cruz Biotechnology |
仅供实验/研究使用。 For experimental / research use only. |
对羟基苯甲酸乙酯 Ethyl p-Hydroxybenzoate
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西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich |
仅供实验/研究使用。 For experimental / research use only. |
4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE ReagentPlus®, 99%
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中诺食品配料 Sinofi Food Ingredients |
Ethylparaben
气味 Odor: characteristic 采用 Use: 防腐剂 Preservative, 化妆品 Cosmetics, 饲料 Feed, 制药业 Pharmaceutical, 汽水 Soft Drink, 醇饮料 Alcohol Beverage, 饮料粉 Beverage Powder, 果汁 Fruit Juice, 布丁 Puddings, 酱料 Sauces, 烘烤食物 Baking Food, 秋刀鱼 Sauage, 调味剂。 Flavoring Agent. |
TCI AMERICA |
仅供实验/研究使用。 For experimental / research use only. |
4-羟基苯甲酸乙酯> 99.0%(gc)(t) Ethyl 4-Hydroxybenzoate >99.0%(GC)(T)
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安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View |
欧洲信息 European information : |
最重要的危害 Most important hazard(s): | xi-刺激性 Xi - Irritant |
r 36/37/38-刺激眼睛 R 36/37/38 - Irritating to eyes, 呼吸系统 respiratory system, and skin 皮. S 02 - 保持 Keep out of the 达到 reach of 孩子们 children. S 24/25 - 避免 Avoid contact with skin 皮 and 眼睛 eyes. S 26 - In 案件 case of contact with 眼睛 eyes, 冲洗 rinse 立即 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical advice. S 36 - 穿 Wear 适当 suitable 保护性 protective 服装 clothing.
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危害识别 Hazards identification |
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物质或混合物的分类 Classification of the substance or mixture |
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
没有找到。 None found. |
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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象形图 Pictogram | |
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危险说明 Hazard statement(s) |
没有找到。 None found. |
防范说明 Precautionary statement(s) |
没有找到。 None found. |
口服/肠胃外毒性 Oral/Parenteral Toxicity: |
口服兔子 口服 oral-rabbit LD50 5000 mg/kg kg (萨巴利奇卡 Sabalitschka & Neufeld-Crzellitzer Neufeld-Crzellitzer,1954)
口鼠 口服 oral-rat LD > 200 mg/kg kg Acta 产科的 Obstetrica et 妇科 Gynaecologica 粳稻 Japonica, 英文版。卷22 English Edition. Vol. 22, pg。 94 Pg. 94, 1975.
灌胃鼠 gavage-rat LD50 [性别 sex: F] 4300 mg/kg kg (ctfa CTFA, 1980b) 1980b)
老鼠 口服 oral-mouse LD50 8000 mg/kg kg (索科尔 Sokol, 1952)
老鼠 口服 oral-mouse LD50 6008 mg/kg kg (佐渡 Sado, 1973)
口头狗 口服 oral-dog LD50 5000 mg/kg kg (萨巴利奇卡 Sabalitschka & Neufeld-Crzellitzer Neufeld-Crzellitzer, 1954)
口头狗 口服 oral-dog LD50 5000 mg/kg kg FAO 营养 Nutrition 会议 Meetings 报告 Report 系列 Series. 卷 Vol. 53A, pg。 81 Pg. 81, 1974.
几内亚口服 口服 oral-guinea 猪 pig LD50 2000 mg/kg kg FAO 营养 Nutrition 会议 Meetings 报告 Report 系列 Series. 卷 Vol. 53A, pg。 81 Pg. 81, 1974.
腹腔内小鼠 intraperitoneal-mouse LD50 520 mg/kg kg Drug Standards. 卷 Vol. 20, pg。 89 Pg. 89, 1952.
老鼠 口服 oral-mouse LD50 3000 mg/kg kg Bromatologia i 化学性 Chemia Toksykologiczna Toksykologiczna. 卷 Vol. 14, pg。 301 Pg. 301, 1981.
口服兔子 口服 oral-rabbit LD50 5000 mg/kg kg FAO 营养 Nutrition 会议 Meetings 报告 Report 系列 Series. 卷 Vol. 53A, pg。 81 Pg. 81, 1974.
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皮肤毒性 Dermal Toxicity: |
未定 Not determined
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吸入毒性 Inhalation Toxicity: |
未定 Not determined
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使用安全信息 Safety in Use Information:
类别 Category: | antioxidants and preservatives |
对羟基苯甲酸乙酯使用水平的建议值 Recommendation for ethyl paraben usage levels up to: | | 不用于香水。 not for fragrance use.
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最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): | 10.00(微克/ 均/天) 10.00 (μg/capita/day) |
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3900(微克/ /天) 3900 (μg/person/day) |
关注点 Threshold of Concern: | 1800(微克/ /天) 1800 (μg/person/day) |
结构类 Structure Class: | I |
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根据委员会法规ec EC号的食品类别。 1565/2000(ec , 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the Industry the "正常 normal" use is 定义的 de精细 fined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 de精细 fined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (efsa EFSA, 2002i)。 2002i). |
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm |
| 平均 average 用法 usage mg/kg kg | 最大 maximum 用法 usage mg/kg kg |
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): | 7.00000 | 35.00000 |
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): | 5.00000 | 25.00000 |
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): | 10.00000 | 50.00000 |
加工水果(04.1) Processed fruit (04.1): | 7.00000 | 35.00000 |
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): | - | - |
糖果(05.0) Confectionery (05.0): | 10.00000 | 50.00000 |
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): | 5.00000 | 25.00000 |
烘焙用具(07.0) Bakery wares (07.0): | 10.00000 | 50.00000 |
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): | 2.00000 | 10.00000 |
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : | 2.00000 | 10.00000 |
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): | - | - |
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): | - | - |
盐 Salts, 香料 spices, 汤类 soups, 酱料 Sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): | 5.00000 | 25.00000 |
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): | 10.00000 | 50.00000 |
不含醇 Non-alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): | 5.00000 | 25.00000 |
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 50.00000 |
即食美味(15.0) Ready-to-eat savouries (15.0): | 20.00000 | 100.00000 |
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 |
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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欧洲食品安全局(efsa EFSA)参考 :
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食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 flavourings, 与调味品组评估有关的委员会的要求20(fge.20)与食品接触的加工助剂和材料(afc) processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical group 23 视图 View page or 视图 View pdf
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调味组评估52(fge.52) Flavouring Group Evaluation 52 (FGE.52): 通过与构烷醇相关的jecfa(第五十七次会议)评估的羟基和烷氧基取代的苄基衍生物的考虑 Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, efsa EFSA在ge FGE.20(2005)(委员会法规(ec EC)2000年7月18日第1565/2000号)中评估的食品及相关酯-食品添加剂科学小组的意见 , 调味料 flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC) 视图 View page or 视图 View pdf
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调味剂评估54(fge.54)[1]-考虑通过jecfa(第五十七次会议)评估与苄醇结构相关的苄基衍生物 Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, 相关的乙a related acetal, efsa EFSA在ge FGE.20(2005)中评估了苯甲酸和相关的酯-食品添加剂专家组的科学观点 , 调味料 flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in 联系 Contact with Food 视图 View page or 视图 View pdf
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调味组评估20 Flavouring Group Evaluation 20, 版本1(fge.20rev1) Revision 1 (FGE.20Rev1): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids and 有关 related esters from chemical group 23 视图 View page or 视图 View pdf
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调味组评估54 Flavouring Group Evaluation 54, 版本1(fge.54rev1) Revision 1 (FGE.54Rev1): 考虑由jecfa(第五十七次会议)评估的与苄醇结构相关的苄基衍生物 Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids and 有关 related esters 已评估 evaluated by by efsa EFSA in ge FGE.20Rev1 (2009) 视图 View page or 视图 View pdf
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调味品组评价的科学见解20 Scientific Opinion on Flavouring Group Evaluation 20, 版本2(fge.20rev2) Revision 2 (FGE.20Rev2): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical 团体 groups 23 and 30 视图 View page or 视图 View pdf
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调味品组评价的科学见解20 Scientific Opinion on Flavouring Group Evaluation 20, 版本3(fge.20rev3) Revision 3(FGE.20Rev3): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical 团体 groups 23 and 30 视图 View page or 视图 View pdf
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调味品组评价的科学见解20 Scientific Opinion on Flavouring Group Evaluation 20, 修订版4(fge.20rev4) Revision 4 (FGE.20Rev4): 苄醇 Benzyl alcohols, benzaldehydes, 相关的乙a related acetal, benzoic acids, and 有关 related esters from chemical 团体 groups 23 and 30 视图 View page or 视图 View pdf
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Epi系统 EPI System: 视图 View |
每日医学 Daily Med:search |
nlm NLM有害物质数据库 :搜索 Search |
辅助引文 AIDS Citations:搜索 Search |
癌症引文 Cancer Citations:搜索 Search |
毒理学引文 Toxicology Citations:搜索 Search |
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search |
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search |
EPA物质注册服务(tsca TSCA) :120-47-8 |
EPA ACToR:毒理学资料 Toxicology Data |
EPA物质注册服务(SRS) :注册表 Registry |
实验室化学安全摘要 Laboratory Chemical Safety Summary :8434 |
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data |
sccnfp SCCNFP:意见 opinion |
德国wgk WGK Germany:1 |
4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE |
chemidplus Chemidplus:0000120478 |
技术 RTECS:CAS#120-47-8的dh2190000 DH2190000 for cas# 120-47-8 |
参考资料 References:
| 4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE |
NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
加拿大国内分公司。清单 Canada Domestic Sub. List: | 120-47-8 |
pubchem(cid) Pubchem (cid): | 8434 |
pubchem(sid) Pubchem (sid): | 134975046 |
其他资料 Other Information:
(iupac) (IUPAC): | 元素的原子量2009 Atomic Weights of the Elements 2009 |
(iupac) (IUPAC): | 元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf) |
影片 Videos: | 元素周期表 The Periodic Table of Videos |
RBC : | 本网站使用的原子量 Atomic Weights use for this web site |
(iupac) (IUPAC): | 元素周期表 Periodic Table of the Elements |
用于食品接触物质的fda间接添加剂 FDA Indirect Additives used in Food Contact Substances: | 视图 View |
CHEBI: | 视图 View |
CHEMBL: | 视图 View |
代谢组学数据库 Metabolomics Database: | 搜索 Search |
KEGG (GenomeNet): | D01647 |
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database): | HMDB32573 |
食物 FooDB: | FDB010510 |
ymdb(酵母代谢组数据库) YMDB (Yeast Metabolome Database): | YMDB01688 |
出口关税代码 Export Tariff Code: | 2918.29.7500 |
fda食品添加剂状况清单 FDA Listing of Food Additive Status: | 视图 View |
雾度图 Haz-Map: | 视图 View |
家庭用品 Household Products: | 搜索 Search |
化学蜘蛛 ChemSpider: | 视图 View |
维基百科 Wikipedia: | 视图 View |
rsc学习化学 RSC Learn Chemistry: | 视图 View |
配方/制剂 Formulations/Preparations: •商品名 •trade names: 庚糖 aseptoform e, bobomold bobomold oe , 依替普尔 easeptol, 乙基丁醚 ethyl butex, 对乙基ethyl parasept, 霉菌素 mycoten, 餐巾 napagin a, 尼日利亚a nipagina a, 尼帕津 nipazin a, br sobrol a, 索洛尔 solbrol a, 和tegosept tegosept e。
•酯通常以含有游离酚基对羟基苯甲酸酯的形式出售 •esters are usually sold in form which contains free phenolic groupparaben esters
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潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在(自然 Occurrence (nature, food, 其他) other): note
| 自然界中找不到 not found in nature |
同义词 Synonyms:
| benzoic acids, 4-羟基 4-hydroxy-, ethyl ester | 4- | carbethoxyphenol | p- | carbethoxyphenol | para- | carbethoxyphenol | | 4-羟基苯甲酸乙酯 ETHYL 4-HYDROXY BENZOATE | | ethyl p-hydroxybenzoate | | ethyl 对羟基苯甲酸酯 para-hydroxybenzoate | | ethyl-4-hydroxybenzoate | | ethyl-p-hydroxybenzoate | | 对羟基苯甲酸乙酯 ethyl-对羟基苯甲酸酯 para-hydroxybenzoate | | ethylparaben | 4- | hydroxy-benzoic acids ethyl ester | 4- | hydroxybenzoic acids ethyl ester | p- | hydroxybenzoic acids ethyl ester | para- | hydroxybenzoic acids ethyl ester | 4- | hydroxybenzoic acids 乙酯 ethylester |
文章 Articles:
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