imidazole
甲酰胺 methanimidamide, N,N'-1,2-亚乙基二 2-ethenediyl-

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    Imidazole, 高极性化合物 a highly polar compound, 已广泛用作ph范围为6.2-7.8的腐蚀抑制剂和缓冲剂。 has been used extensively as a corrosion inhibitor and a buffer in the pH range of 6.2-7.8.
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    gb9580咪唑 GB9580 Imidazole
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    i0288咪唑[用于缓冲液]> 99.0%(gc)(t) I0288 Imidazole [for Buffer] >99.0%(GC)(T)
Name:1h-咪唑 1H-imidazole
CAS号 CAS Number: 288-32-4Picture of molecule3D/INCHI
其他 Other:116421-26-2
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:206-019-2
FDA UNII:7GBN705NH1
nikkaji网站 Nikkaji Web:J2.566F
贝尔斯坦数 Beilstein Number:0103853
XlogP3:-0.10(est) -0.10 (est)
分子量 Molecular Weight:68.07888000
式 Formula:c3 h4 n2 C3 H4 N2
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:buffering agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 90.50 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 257.00 °C. @ 760.00 mm 汞 Hg
蒸汽压力 Vapor Pressure:0.024000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est)
闪点 Flash Point: 293.00 °F. tcc TCC ( 145.00 °C. )
logp(o / w) logP (o/w): -0.080
溶于 Soluble in:
 水 water, 1.591e + 005 mg / l @ 25°c(est) 1.591e+005 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: buffering agents
 
供应商 Suppliers:
乙酰苯 Aceto
Imidazole
巴斯夫 BASF
Imidazole
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
咪唑95% Imidazole 95%
气味 Odor: characteristic
采用 我们 Use: Imidazole, 高极性化合物 a highly polar compound, 已广泛用作ph范围为6.2-7.8的腐蚀抑制剂和缓冲剂。 has been used extensively as a corrosion inhibitor and a buffer in the pH range of 6.2-7.8.
Charkit Chemical
咪唑 IMIDAZOLE ACS
Glentham Life Sciences
Imidazole, 99.5%
Glentham Life Sciences
Imidazole
OQEMA
Imidazole
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
咪唑≥99% Imidazole ≥99%
西格玛·奥尔德里奇 Sigma-Aldrich
仅供实验/研究使用。 For experimental / research use only.
咪唑ACS试剂 , ≥99%(滴定) ≥99% (titration)
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
咪唑[用于缓冲液]> 99.0%(gc)(t) Imidazole [for Buffer] >99.0%(GC)(T)
 
安全信息 Safety Information:
首选sds SDS : 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
几内亚口服 oral-guinea 猪 pig LD50 760 mg/kg
Przeglad 流行病学 Epidemiologiczny. 卷 Vol. 67, pg。 295 Pg. 295, 1993.

哺乳动物 oral-mammal (种类 species 未指定 unspecified) LD50 1000 mg/kg
农药 Pesticide 化学药品 Chemicals 官方 Official 概要 Compendium, 美国农药管制官员协会 Association of the American Pesticide Control Officials, 公司 Inc., 1966。 -- 1966. Vol. -, pg。 608 Pg. 608, 1966.

intraperitoneal-老鼠 mouse LD50 300 mg/kg
国民 National 技术 Technical Information 服务 Service. 卷 Vol. AD277-689

intravenous-老鼠 mouse LD50 475 mg/kg
行为的 BEHAVIORAL: 抽搐 CONVULSIONS OR 影响 EFFECT ON 发作 SEIZURE THRESHOLD
Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 33, pg。 716 Pg. 716, 1983.

oral-老鼠 mouse LD50 880 mg/kg
German 违法行为 Offenlegungsschrift 专利 Patent 文献 Document. 卷 Vol. #3046325

口鼠 oral-rat LD50 220 mg/kg
Przeglad 流行病学 Epidemiologiczny. 卷 Vol. 67, pg。 295 Pg. 295, 1993.

皮肤毒性 Dermal Toxicity:
皮下猫 subcutaneous-cat ldlo LDLo 125 mg/kg
行为的 BEHAVIORAL: 刚度 REGIDITY 行为的 BEHAVIORAL: FOOD 录取 INta TAKE (动物 ANIMAL)
档案 Archiv 富尔 fuer 实验 Experimentelle 病理学 Pathologie und 药理学 Pharmakologie. 卷 Vol. 84, pg。 155 Pg. 155, 1918.

皮下犬 subcutaneous-dog LD50 28 mg/kg
Przeglad 流行病学 Epidemiologiczny. 卷 Vol. 67, pg。 295 Pg. 295, 1993.

subcutaneous-老鼠 mouse LD50 817 mg/kg
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 119, pg。 444 Pg. 444, 1957.

皮下大鼠 subcutaneous-rat LD50 626 mg/kg
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 119, pg。 444 Pg. 444, 1957.

吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: buffering agents
咪唑用量建议不超过 Recommendation for imidazole usage levels up to:
 不用于香水。 not for fragrance use.
 
咪唑风味使用水平的推荐值 Recommendation for imidazole flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
EPA物质注册服务(tsca TSCA) :288-32-4
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :795
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
1h-咪唑 1H-imidazole
chemidplus Chemidplus:0000288324
技术 RTECS:用于CAS#288-32-4的ni3325000 NI3325000 for cas# 288-32-4
 
参考资料 References:
 1h-咪唑 1H-imidazole
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:288-32-4
pubchem(cid) Pubchem (cid):795
pubchem(sid) Pubchem (sid):134974460
信息基 Pherobase:视图 View
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
代谢组学数据库 Metabolomics Database:搜索 Search
KEGG (GenomeNet):C01589
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB01525
食物 FooDB:FDB012307
出口关税代码 Export Tariff Code:2933.29.6000
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 十字花 spathiphyllum floribundum
搜索 Search Trop Picture
 
同义词 Synonyms:
1,3-diaza-2,4-cyclopentadiene
1,3-diazacyclopenta-2,4-diene
1,3-diazole
5-dihydro-1h-咪唑 1H-imidazole
N,n'-1 N'-1,2-ethenediyl甲酰胺 methanimidamide
 乙二醛 乙二醛 glyoxalin
 乙二醛 乙二醛 乙二醛 glyoxaline
 IMD
1H-imidazol
1H-imidazole
mono-imidazole
 义乌 imutex
 甲酰胺 methanimidamide, N,n'-1 N'-1,2-亚乙基二 2-ethenediyl-
 咪唑 miazole
 pyrro(b)monazole
N,N'-vinyleneformamidine
 

文章 Articles:

已发布 PubMed:卢立康唑用于治疗真菌感染 Luliconazole for the treatment of fungal infections: 循证审查。 an evidence-based review.
已发布 PubMed:用于反相液相色谱的新型尿素官能化表面受限的十八酰亚胺咪唑离子液体硅胶固定相。 A novel urea-functionalized surface-confined octadecylimidazolium ionic liquid silica stationary phase for reversed-phase liquid chromatography.
已发布 PubMed:离子液体包裹的磁性核/壳fe3o4 @ sio2纳米颗粒,用于食品样品中利尿隆的分离/分析。 Ionic liquid coated magnetic core/shell Fe3O4@SiO2 nanoparticles for the separation/analysis of linuron in food samples.
已发布 PubMed:(13)c-标记的2-乙酰基-4-((1r Correction to Synthesis and Application of (13)C-Labeled 2-Acetyl-4-((1R,2s 2S,3r)-1 3R)-1,2,3,4-四羟基丁基)咪唑(thi) 4-tetrahydroxybutyl)imidazole (THI), 一种在焦糖食用色素中观察到的免疫抑制剂。 an Immunosuppressant Observed in Caramel Food Colorings.
已发布 PubMed:5-Amino-5'-bromo-6-(4-methyl-苯并 benzo-yl)-8-硝基 nitro-2,3-二氢-1h-螺-咪唑[1 3-di-hydro-1H-spiro-[imidazo[1, 2-a 2-a]吡啶-7 ,3'-indolin]-2'-one 包含 including an 未知 unk现在 nown 溶剂化 solvate.
已发布 PubMed:慢性中枢ampk的激活减弱了糖尿病大鼠中葡萄糖刺激的胰岛素分泌,并加剧了肝胰岛素抵抗。 Chronic activation of central AMPK attenuates glucose-stimulated insulin secretion and exacerbates hepatic insulin resistance in diabetic rats.
已发布 PubMed:判定 De终止 termination of 焦糖 caramel 着色剂 颜色 colorants' 副产品 by by-products in 液体 liquid 食物 foods by by 超高性能 ultra-高性能的 高 high-performance 液体 liquid 色谱串联 色谱法 chromatography-串联 tandem mass 光谱法 spectrometry (uplc-ms UP液晶显示器 lc LC-ms MS/ms MS).
已发布 PubMed:毛细管区带电泳法测定果汁和花蜜中的主要金属阳离子 [Determination of major metal cations in juices and nectars by capillary zone electrophoresis].
已发布 PubMed:隔离 Isolation, 瑞替加滨的两种新型过程相关杂质的鉴定和结构解析。 identification and structure elucidation of two novel process-related impurities of retigabine.
已发布 PubMed: natrinema 加里 gari bcc 24369的组胺脱氢酶的结晶和初步晶体学分析。
已发布 PubMed:新型有效的非咪唑组胺h 1受体拮抗剂st-1283的抗焦虑和抗抑郁样活性。 Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H₃ receptor antagonist ST-1283.
已发布 PubMed:离子液体作为电解质添加剂的毛细管电泳测定软饮料中的防腐剂 Determination of preservatives in soft drinks by capillary electrophoresis with ionic liquids as the electrolyte additives.
已发布 PubMed:2-乙酰基-4-((1r)抑制 吡x醛激酶 Inhibition of human pyridoxal kinase by 2-acetyl-4-((1R,2s 2S,3r)-1 3R)-1,2,3,4-四羟基丁基)咪唑(thi)。 4-tetrahydroxybutyl)imidazole (THI).
已发布 PubMed:2-苯基-4的致敏化学发光 Sensitized chemiluminescence of 2-phenyl-4,5-二(2-呋喃基)-1h-咪唑/ kfe(cn)₆/没食子酸丙酯体系与固相萃取相结合测定食用油中没食子酸丙酯。 5-di(2-furyl)-1H-imidazole/K₃Fe(CN)₆/propyl gallate system combining with solid-phase extraction for the determination of propyl gallate in edible oil.
已发布 PubMed:肥胖的前瞻性治疗剂 Prospective therapeutic agents for obesity: 中枢和外周作用的选择性大麻素1受体拮抗剂的分子修饰方法。 molecular modification approaches of centrally and peripherally acting selective cannabinoid 1 receptor antagonists.
已发布 PubMed:一种基于ail / il的液/液提取系统,用于纯化带有组氨酸标签的蛋白质。 An AIL/IL-based liquid/liquid extraction system for the purification of His-tagged proteins.
已发布 PubMed:鹰嘴豆螯合肽抑制铜介导的脂质过氧化。 Chickpea chelating peptides inhibit copper-mediated lipid peroxidation.
已发布 PubMed:对橙花纤维化机制的新见解 New insights into the mechanism of neurolathyrism: l-β-odap通过瞬时受体电位通道和代谢型谷氨酸受体在原发性运动橙花元中触发[ca2 +] i积累和细胞死亡。 L-β-ODAP triggers [Ca2+]i accumulation and cell death in primary motor neurons through transient receptor potential channels and metabotropic glutamate receptors.
已发布 PubMed: 液晶显示器 lc LC-ms MS / ms MS法测定焦糖色和加工食品中的4-甲基咪唑和2-乙酰基-4()-四羟基丁基咪唑
已发布 PubMed: 新型cox-2选择性抑制剂西米考昔 cimicoxib在犬中的药代动力学特征。
已发布 PubMed:使用预定的ph值调节表面活性剂样肽a6h的螯合。 Tuning chelation by the surfactant-like peptide A6H using predetermined pH values.
已发布 PubMed:新型基于导电聚合物的生物传感器的开发。 Development of a novel biosensor based on a conducting polymer.
已发布 PubMed:念珠菌病(口咽)。 Candidiasis (oropharyngeal).
已发布 PubMed:酪氨酸酶从巨大芽孢杆菌吸收铜的机理。 The mechanism of copper uptake by tyrosinase from Bacillus megaterium.
已发布 PubMed:标记的蛋白质的定向固定在金电极上沉积的dpta-cu(ii)层的氧化还原活性硫醇衍生物上-电化学生物传感器的基础。 Oriented immobilization of His-tagged protein on a redox active thiol derivative of DPTA-Cu(II) layer deposited on a gold electrode--the base of electrochemical biosensors.
已发布 PubMed:2,3,7,8-四氯二苯并-p-二恶英(tcdd)通过p38 / jnk mapk途径诱导小胶质一氧化氮的产生和随后的大鼠原代皮层橙花元凋亡。 8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway.
已发布 PubMed:杂环化合物对单糖和多糖氨氧化的形成和生态毒性 Formation and ecotoxicity of N-heterocyclic compounds on ammoxidation of mono- and polysaccharides.
已发布 PubMed:纯化 Purification, 大豆成熟大豆球蛋白a1bb2的结晶和初步晶体学分析。 crystallization and preliminary crystallographic analysis of soybean mature glycinin A1bB2.
已发布 PubMed:环磷杀虫剂 Cycloxaprid insecticide: 烟碱乙酰胆碱受体的结合位点和代谢。 nicotinic acetylcholine receptor binding site and metabolism.
已发布 PubMed:(13)c-标记的2-乙酰基-4-((1r Correction to Synthesis and Application of (13)C-Labeled 2-Acetyl-4-((1R,2s 2S,3r)-1 3R)-1,2,3,4-四羟基丁基)咪唑(thi) 4-tetrahydroxybutyl)imidazole (THI), 一种在焦糖食用色素中观察到的免疫抑制剂。 an Immunosuppressant Observed in Caramel Food Colorings.
已发布 PubMed:一种改进的gc-ms方法,用于测定不同类型的生物样品中的甘油。 An improved GC-MS method in determining glycerol in different types of biological samples.
已发布 PubMed:唑类杀真菌剂以多加方式干扰多巴胺能pc12细胞中的细胞内Ca2 +。 Azole fungicides disturb intracellular Ca2+ in an additive manner in dopaminergic PC12 cells.
已发布 PubMed:毛细管区带电泳快速,选择性分离方法测定金枪鱼样品中组胺的研究进展 Development of a fast and selective separation method to determine histamine in tuna fish samples using capillary zone electrophoresis.
已发布 PubMed:克罗顿·莱希莱里·穆尔arg。 (大戟科)茎皮精油可能是诱变保护性食品成分,可抵抗熟食中的杂环胺。 Croton lechleri Müll. Arg. (Euphorbiaceae) stem bark essential oil as possible mutagen-protective food ingredient against heterocyclic amines from cooked food.
已发布 PubMed: 透水 diaqua-bis-(1h-咪唑-4-羧基-κ-(2)n(3) ,o(4))锰(ii)。 O (4))manganese(II).
已发布 PubMed:gtp环水解酶的结构和反应机理。 Structures and reaction mechanisms of GTP cyclohydrolases.
已发布 PubMed:分子表征 Molecular characterization, 苯并咪唑抗药性青霉菌的适应性和真菌毒素生产。 fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.
已发布 PubMed:左旋肌氨酸调节中性粒细胞生物化学和功能中的呼吸爆发和活性氧的产生 L-carnosine modulates respiratory burst and reactive oxygen species production in neutrophil biochemistry and function: 非口服二肽左旋肌氨酸补体的口服剂型可抗感染,抗流感 may oral dosage form of non-hydrolized dipeptide L-carnosine complement anti-infective anti-influenza flu treatment, 预防和自我保健可以替代常规越橘? prevention and self-care as an alternative to the conventional vaccination?
已发布 PubMed:合成 Synthesis, 杀菌活性 fungicidal activity, 和2-偶氮基-3的固醇14α-脱甲基酶结合相互作用 and sterol 14α-demethylase binding interaction of 2-azolyl-3,指状青霉菌上的4-二氢喹唑啉。 4-dihydroquinazolines on Penicillium digitatum.
已发布 PubMed:酪蛋白地图 Casein maps: 乙醇的作用 effect of ethanol, ph pH, 温度 temperature, 和cacl2对重构酪蛋白胶束的粒径的影响。 and CaCl2 on the particle size of reconstituted casein micelles.
已发布 PubMed:2-甲基咪唑的测定 Determination of 2-methylimidazole, 4-甲基咪唑和2-乙酰基-4-(1 4-methylimidazole and 2-acetyl-4-(1,2,3,焦糖色素和可乐中的4-四羟基丁基)咪唑,使用lc / ms / ms。 4-tetrahydroxybutyl)imidazole in caramel colours and cola using LC/MS/MS.
已发布 PubMed:三氟甲唑是小鼠的一种肥胖原,它通过过氧化物酶体增殖物激活的受体γ(pparγ)起作用。 Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ).
已发布 PubMed:毛细管电泳快速测定蜂蜜中的阳离子 Fast determination of cations in honey by capillary electrophoresis: 一种可能的地理来源歧视方法。 a possible method for geographic origin discrimination.
已发布 PubMed: 聚[透水 diaqua-(μ(5)-1h-咪唑-4 ,5-二羧基-ato)(μ(4)-1h-咪唑-4 5-di-carboxyl-ato)(μ(4)-1H-imidazole-4,5-二羧基-氨基)三-银(i)y(iii)]。 5-di-carboxyl-ato)tris-ilver(I)ytterbium(III)].
已发布 PubMed:血红蛋白和肌球蛋白中的位点e14 Site E14 in hemoglobins and myoglobins: 影响血红素损失和脂质氧化能力的关键残基。 a key residue that affects hemin loss and lipid oxidation capacity.
已发布 PubMed:强磷光铱(iii)-卟啉-具有可调节光物理性质和功能的新型氧指示剂。 Strongly Phosphorescent Iridium(III)-Porphyrins - New Oxygen Indicators with Tuneable Photophysical Properties and Functionalities.
已发布 PubMed:植物油中一氯丙二醇酯的直接和间接定量Comparison of indirect and direct quantification of esters of monochloropropanediol in vegetable oil.
已发布 PubMed:脑室注射二甲双胍可抑制Ghrelin诱导的下丘脑amp激酶信号传导和食物摄入。 Intracerebroventricular administration of metformin inhibits ghrelin-induced Hypothalamic AMP-kinase signalling and food intake.
已发布 PubMed:葡萄糖与咪唑在水溶液中相互作用的分子动力学模拟。 Molecular dynamics simulations of the interaction of glucose with imidazole in aqueous solution.
已发布 PubMed:同时定量2-乙酰基-4-四羟基丁基咪唑 Simultaneous quantitation of 2-acetyl-4-tetrahydroxybutylimidazole, 2-和4-甲基咪唑 2- and 4-methylimidazoles, 高效液相色谱-串联质谱法测定饮料中的5-羟甲基糠醛 and 5-hydroxymethylfurfural in beverages by ultrahigh-performance liquid chromatography-tandem mass spectrometry.
已发布 PubMed:弱水合的表面和小的生物溶质的结合相互作用。 Weakly hydrated surfaces and the binding interactions of small biological solutes.
已发布 PubMed:(η-全基)溴(1-苯基-1h-咪唑-κn)钯(ii)。 (η-All-yl)bromido(1-phenyl-1H-imidazole-κN)palladium(II).
已发布 PubMed:4-取代甲氧基苯甲酰基-芳基-噻唑和2-芳基-4-苯甲酰基-咪唑的药代动力学优化,可提高口服生物利用度。 Pharmacokinetic optimization of 4-substituted methoxybenzoyl-aryl-thiazole and 2-aryl-4-benzoyl-imidazole for improving oral bioavailability.
已发布 PubMed:食品中阿维菌素残留的验证研究。 Validation study on avermectine residues in foodstuffs.
已发布 PubMed:采用 我们 Use of 离子的 ionic 液体 liquid 总量 aggregates of 1-hexadecyl-3-butyl 咪唑鎓 imidazolium 溴化物 bromide in a 聚焦微波 焦点 foc用过的 used-micro波 wave assisted extraction method 跟着 fol低 lowed by by 高性能的 高 high-performance 液体 liquid 色谱法 chromatography with 紫外线 ultraviolet and 萤光 流感 fluorescence 检测 detection to 确定 determine the 15+1 欧洲联盟 EU 优先 priority 帕斯 PAHs in 烤 toasted 谷物 cereals ("gofios gofios").
已发布 PubMed:丁酸钠诱导的 结肠癌细胞凋亡中需要钙存储的钙进入。 Requirement for store-operated calcium entry in sodium butyrate-induced apoptosis in human colon cancer cells.
已发布 PubMed: 甜瓜(cucumis 旋律 melo l。)的近等基因系的细胞壁多糖及其近交亲本表现出不同的果肉硬度或生理行为。
已发布 PubMed:橙花肽受体 Neuropeptide S receptor: 非肽拮抗剂发现的最新进展。 recent updates on nonpeptide antagonist discovery.
已发布 PubMed:[使用咪唑离子液体对二氧化硫的吸附性能]。 [Adsorption performances for sulfur dioxide using imidazole ionic liquids].
已发布 PubMed:变量对烤猪肉和鲭鱼中杂环胺(hca)形成的影响。 Effects of cooking variables on formation of heterocyclic amines (HCA) in roasted pork and mackerel.
已发布 PubMed:小果皮果不同发育阶段的代谢变化 Metabolic alterations in different developmental stages of Pilocarpus microphyllus.
已发布 PubMed:植物生长调节剂 Plant-growth regulator, 咪唑-4-羧酰胺 imidazole-4-carboxamide, 由仙灵形成的环,形成真菌的lepista 索尔达 sordida。
已发布 PubMed:组胺 Histaminol: 酒中新化合物的鉴定和hplc分析。 identification and HPLC analysis of a novel compound in wine.
已发布 PubMed:咪唑rib碱肠道吸收增加 Increased intestinal absorption of mizoribine, 免疫抑制剂 an immunosuppressive agent, 在 淤积的大鼠中。 in cholestatic rats.
已发布 PubMed:一氧化氮合酶抑制剂1-(2-三氟甲基苯基)-咪唑(trim)和7-硝基吲唑(7-ni)对小鼠学习和记忆的影响 Effects of nitric oxide synthase inhibitors 1-(2-trifluoromethylphenyl)--imidazole (TRIM) and 7-nitroindazole (7-NI) on learning and memory in mice.
已发布 PubMed:醇聚合物中的迁移物的分析和化学。 Analysis and chemistry of migrants from wine fining polymers.
已发布 PubMed:萝卜硫烷对 血管内皮细胞抵抗脂多糖诱导的炎症损伤的保护作用。 Protective effect of sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage.
已发布 PubMed:各种精制处理后确定葡萄转化酶含量(使用pta-elisa)与葡萄酒总蛋白含量的变化。与葡萄酒起泡性的关系。 Detection and quantification of maitotoxin-like compounds using a neuroblastoma (Neuro-2a) cell based assay. Application to the screening of maitotoxin-like compounds in Gambierdiscus spp.
已发布 PubMed:克隆 Cloning, 表达 expression, 樟脑的硫氧还蛋白还原酶cdna的合成及鉴定。 and characterization of a thioredoxin reductase cDNA from Taiwanofungus camphorata.
已发布 PubMed:以2-联芳基乙基咪唑为轰击蛋白受体亚型3(brs-3)激动剂的衍生物的合成和sar的治疗。 Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
已发布 PubMed:来自深海沉积物的真菌青霉sp。的生物碱。及其抗肿瘤活性。 Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities.
已发布 PubMed:他的 Histamine 改性 modified 2'-deoxyribo腺苷 adenosine--有力的 potential 铜 copper 捆绑 binding site in 核酶 脱氧核糖核酸 DNAzymes.
已发布 PubMed:螯合朗缪尔-布洛杰特电影 Chelating Langmuir-Blodgett film: 用于生物传感器应用的新型多功能化学发光传感层。 a new versatile chemiluminescent sensing layer for biosensor applications.
已发布 PubMed:依马西苯咪唑甲基和依马西苯咪唑酸质子化解离反应与其在土壤中的吸附和非生物降解有关。 Protonation-dissociation reactions of imazamethabenz-methyl and imazamethabenz-Acid in relation to their soil sorption and abiotic degradation.
已发布 PubMed:克隆 Cloning, 表达 expression, 并从樟脑(台湾真菌 Taiwano菌 funguscamphorata)同时具有戊二醛还原酶和脱氢抗坏血酸还原酶活性的酶的表征。
已发布 PubMed:碳纳米管通过诱导对钙进入抑制剂敏感的细胞外Ca2 +流入来激活血小板。 Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors.
已发布 PubMed:nrf2在合成三萜类cddo-咪唑啉化物预防高脂饮食诱导的肥胖中的作用。 Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide.
已发布 PubMed:大麻素1受体拮抗剂sr141716a的酰肼药效团的生物立体置换。第一部分 Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: 有力的 potent, 口头活动1 orally-active 1,4-二取代的咪唑。 4-disubstituted imidazoles.
已发布 PubMed:使用超高压液相色谱-四极杆飞行时间ms来发现食品样品中农药代谢物的存在。 Use of ultra-high-pressure liquid chromatography-quadrupole time-of-flight MS to discover the presence of pesticide metabolites in food samples.
已发布 PubMed:橡蚕全长cdna文库的构建及与停滞有关的kk-42结合蛋白基因鉴定 Construction of a full-length cDNA Library from Chinese oak silkworm pupa and identification of a KK-42-binding protein gene in relation to pupa-diapause termination.
已发布 PubMed:光诱导的色氨酸和组氨酸氧化。芳族n-杂环对三重激发黄素的反应性 Light-induced oxidation of tryptophan and histidine. Reactivity of aromatic N-heterocycles toward triplet-excited flavins.
已发布 PubMed:克隆 Cloning, 表达 expression, 马铃薯(番薯叶番荔枝)的功能性谷胱甘肽还原酶的纯化和纯化 and purification of a functional glutathione reductase from sweet potato (Ipomoea batatas [L.] Lam): 动力学研究和表征。 kinetic studies and characterization.
已发布 PubMed:使用lif检测在mekc中使用头柱场增强的样品堆叠技术分析脂肪胺 Analysis of aliphatic amines using head-column field-enhanced sample stacking in MEKC with LIF detection.
已发布 PubMed:杀真菌剂伊玛沙利在 肠道caco-2细胞中对cyp1a1的诱导和对cyp3a4的抑制与其他康唑类农药的比较。 CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides.
已发布 PubMed:二芳基咪唑恶二唑和噻二唑衍生物作为大麻素cb1受体拮抗剂。 Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists.
已发布 PubMed: 花生四烯酸增加白念珠菌和dubliniensis dubliniensis念珠菌的抗真菌药性。
已发布 PubMed:小麦胚芽脂肪酶催化活性基团的鉴定 [Identification of catalytically active groups of wheat (Triticum aestivum L.) germ lipase].
已发布 PubMed:米曲霉高效生产和部分表征天冬氨酰氨肽酶。 Efficient production and partial characterization of aspartyl aminopeptidase from Aspergillus oryzae.
已发布 PubMed:胡萝卜细胞壁中酚的特征和分布。 Characterization and distribution of phenolics in carrot cell walls.
已发布 PubMed:小麦幼苗中超氧化物歧化酶的分离和鉴定 Isolation and characterization of superoxide dismutase from wheat seedlings.
已发布 PubMed:浅表真菌感染患者的综合管理 Comprehensive management of patients with superficial fungal infections: 硝酸舍他康唑的作用。 the role of sertaconazole nitrate.
已发布 PubMed:2-取代的哌嗪衍生的咪唑羧酰胺作为有效的和选择性的cck1r激动剂,可用于治疗肥胖症。 2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.
已发布 PubMed:咪唑羧酰胺作为强效和选择性cck1r激动剂的发现。 Discovery of imidazole carboxamides as potent and selective CCK1R agonists.
已发布 PubMed:研究2-甲基-3-乙基-4-苯基-δ-4-环己烯羧酸(orf 3858)及其对羟基化代谢产物对子宫摄取3h-雌二醇-17β的影响。 Stabilization of thin-layer agarose gels after isoelectric focusing with polyacrylamide enables reverse imidazole-zinc staining and facilitates two-dimensional gel electrophoresis.
已发布 PubMed:心切割二维液相色谱法定量2-乙酰-4-(1 Heart-cutting two-dimensional liquid chromatography methods for quantification of 2-acetyl-4-(1,2,3,iii类焦糖色的4-四羟基丁基)咪唑 4-tetrahydroxybutyl)imidazole in Class III caramel colours.
已发布 PubMed:在2-甲基咪唑存在下使用 氏菌生产番茄红素 Lycopene production using Blakeslea trispora in the presence of 2-methyl imidazole: 让 yield, 选择性 selectivity, 和安全方面。 and safety aspects.
已发布 PubMed:甘薯(番薯叶番荔枝)的脱氢抗坏血酸还原酶cdna Dehydroascorbate reductase cDNA from sweet potato (Ipomoea batatas [L.] Lam): 表达 expression, 酶性质 enzyme properties, 和动力学研究。 and kinetic studies.
已发布 PubMed:扩散波谱研究酪蛋白胶束与乳胶液滴之间发生的胶体相互作用 Diffusing wave spectroscopy study of the colloidal interactions occurring between casein micelles and emulsion droplets: 与硬球行为的比较。 comparison to hard-sphere behavior.
已发布 PubMed: 工程菌dab DAB制备非糖基化 酪蛋白巨肽。
已发布 PubMed:纯胶束液相色谱法测定肉类样品中的鹅肌苷和肌肽。 Anserine and carnosine determination in meat samples by pure micellar liquid chromatography.
已发布 PubMed:新型选择性大麻素cb1受体反向激动剂的表征 Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, 咪唑24b Imidazole 24b, 在啮齿动物中。 in rodents.
已发布 PubMed:厚朴酚对苯并(a)re诱导的小鼠致死性的抗破伤作用。 Anti-clastogenic effect of magnolol on benzo(a)pyrene-induced clastogenicity in mice.
已发布 PubMed:吡虫啉在水溶液中的光解途径 Photolysis pathway of imazapic in aqueous solution: 中间体的超高分辨率质谱分析。 ultrahigh resolution mass spectrometry analysis of intermediates.
已发布 PubMed: 代谢刺激剂和抑制剂通过blakeslea Blakeslea 三孢菌属 trispora nrrl 2895和2896增强β-胡萝卜素和番茄红素生产的用途。
已发布 PubMed:单克隆免疫测定法在果汁中咪唑的测定中的应用 Application of a monoclonal-based immunoassay for the determination of imazalil in fruit juices.
已发布 PubMed:全反式抗坏血酸在成肌细胞中激活p38 / mef2c途径。 Activation of p38/MEF2C pathway by all-trans retinoic acid in cardiac myoblasts.
已发布 PubMed:在高静水压下原位测量β-乳球蛋白溶液中ph的变化。 In situ measurements of pH changes in beta-lactoglobulin solutions under high hydrostatic pressure.
已发布 PubMed:莫能菌素以不依赖钠离子的方式引起短暂的钙离子流入小鼠脾淋巴细胞。 Monensin causes transient calcium ion influx into mouse splenic lymphocytes in a sodium ion-independent fashion.
已发布 PubMed:[3-一氯丙烷-1的测定 [Determination of 3-monochloropropane-1,固相萃取-气相色谱/负化学电离质谱法测定水解植物蛋白和大豆中的2-二醇] 2-diol in hydrolyzed vegetable proteins and soy by solid phase extraction and gas chromatography/negative chemical ionization-mass spectrometry].
已发布 PubMed:{mun {mu-N,N'-Bis[3-(二甲氨基 dimethyl氨基 amino)propyl]草酰胺 oxamidato(2-)-kappa -kappa(6)N,N',O':N'',N''',o}双[(1h-咪唑-app3)(甲醇-)铜(ii)]双(高氯酸盐)。 O}bis[(1H-imidazole-kappaN3)(methanol-kappaO)copper(II)] bis(perchlorate).
已发布 PubMed:超临界流体萃取(sfe)4(5)-甲基咪唑(4-mei)和2-乙酰基-4(5)-(1 Supercritical fluid extraction (SFE) of 4(5)-methylimidazole (4-MeI) and 2-acetyl-4(5)-(1,2,3,4)研磨咖啡中的四羟基丁基咪唑(thi),采用高效液相色谱-电喷雾质谱定量(hplc / esi-ms)。 4)-tetrahydroxybutyl-imidazole (THI) from ground-coffee with high-performance liquid chromatographic-electrospray mass spectrometric quantification (HPLC/ESI-MS).
已发布 PubMed:昔洛芬大鼠反复给药后耐受的证据 Evidence for tolerance following repeated dosing in rats with ciproxifan, 但不适用于a-304121。 but not with A-304121.
已发布 PubMed:醌遇到氨基酸时 When quinones meet amino acids: chemical, 物理和生物后果。 physical and biological consequences.
已发布 PubMed:固相萃取4(5)-甲基咪唑(4mei)和2-乙酰基-4(5)-(1 Solid-phase extraction of 4(5)-methylimidazole (4MeI) and 2-acetyl-4(5)-(1,2,3,食品和饮料中的4-四羟基丁基)-咪唑(thi),随后进行液相色谱-电喷雾质谱定量。 4-tetrahydroxybutyl)-imidazole (THI) from foods and beverages with subsequent liquid chromatographic-electrospray mass spectrometric quantification.
已发布 PubMed:咪唑衍生物的遗传毒性和气生特性。 Genotoxic and aneugenic properties of an imidazole derivative.
已发布 PubMed:丙草胺 Prochloraz: 具有多种作用机理的咪唑类杀菌剂。 an imidazole fungicide with multiple mechanisms of action.
已发布 PubMed:黑皮质素4-受体反向激动剂的外周给药可防止荷瘤小鼠瘦体重的损失。 Peripheral administration of a melanocortin 4-receptor inverse agonist prevents loss of lean body mass in tumor-bearing mice.
已发布 PubMed:大麻素介导的细胞内钙升高 Cannabinoid-mediated elevation of intracellular calcium: 结构-活动关系。 a structure-activity relationship.
已发布 PubMed: 奥美沙坦 olmesartan 美多西米 medoxomil的结构和功能特征综述 , 血管紧张素受体阻滞剂。 an angiotensin receptor blocker.
已发布 PubMed:果胶固定化果胶酶的制备及其性质。 Preparation and properties of an immobilized pectinlyase for the treatment of fruit juices.
已发布 PubMed:组胺h3受体模型通过经典h3拮抗剂的结构-活性关系的验证。 Validation of a histamine H3 receptor model through structure-activity relationships for classical H3 antagonists.
已发布 PubMed: 硅藻thallassiosira 魏氏菌 weissflogii的冈比亚超氧化物歧化酶同工酶的生化特征 : 克隆 Cloning, 表达 expression, 和酶的稳定性。 and enzyme stability.
已发布 PubMed:舍他康唑 Sertaconazole: 局部抗真菌药的更新评论。 updated review of a topical antifungal agent.
已发布 PubMed:一种竞争性酶联免疫吸附法,检测由亚硝基二甲基胺暴露引起的7-甲基鸟苷加合物。 A competitive ELISA detecting 7-methylguanosine adduct induced by N-nitrosodimethylamine exposure.
已发布 PubMed:h3受体拮抗剂/反向激动剂的药理学和潜在的抗肥胖特性评估。 Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists.
已发布 PubMed:反式和顺式白藜芦醇可增加a7r5血管平滑肌细胞的胞质钙水平。 Trans- and cis-resveratrol increase cytoplasmic calcium levels in A7r5 vascular smooth muscle cells.
已发布 PubMed: 硅藻thallassiosira 魏氏菌 weissflogii的fe / mn超氧化物歧化酶的表征 : 克隆 Cloning, 表达 expression, 和财产。 and property.
已发布 PubMed: 决明子茶(决明子托拉 tora l。)的抗原毒性 : 作用机理和焙烧过程的影响。 mechanism of action and the influence of roasting process.
已发布 PubMed:西兰花的一种成分萝卜硫烷抑制食物衍生的杂环胺的致突变性。 Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.
已发布 PubMed: 工橙花网络预测一系列咪唑衍生物的抗菌活性。 Artificial neural networks for prediction of antibacterial activity in series of imidazole derivatives.
已发布 PubMed:鳕鱼蛋白提取物可稳定水包油乳剂。 Stabilization of oil-in-water emulsions by cod protein extracts.
已发布 PubMed:智商和4-羟基香豆素的分子复合物 Molecular complexes of IQ and 4-hydroxy-coumarin: 诱变抗诱变系统。 a mutagen-anti-mutagen system.
已发布 PubMed:设计 Design, 合成 Synthesis, 2-环己基-4-苯基-1h-咪唑的合成与生物学评价 and biological evaluation of substituted 2-cyclohexyl-4-phenyl-1H-imidazoles: 有力和选择性的橙花肽γγ5受体拮抗剂。 potent and selective neuropeptide Y Y5-receptor antagonists.
已发布 PubMed:啤酒对大鼠结肠杂环胺诱变和肽诱导异常隐窝灶的抑制作用。 Inhibitory effects of beer on heterocyclic amine-induced mutagenesis and PhIP-induced aberrant crypt foci in rat colon.
已发布 PubMed:A-331440的减肥功效 Antiobesity effects of A-331440, 一种新型的非咪唑组胺h3受体拮抗剂。 a novel non-imidazole histamine H3 receptor antagonist.
已发布 PubMed:2- [2- [2-(5-溴-2-甲氧基苯基)-乙基] -3-氟苯基] -4的鉴定 Identification of 2-[2-[2-(5-bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-二氢-1h-咪唑(ml00253764) 5-dihydro-1H-imidazole (ML00253764), 一种小分子的黑皮质素4受体拮抗剂,可有效减少小鼠模型中肿瘤引起的体重减轻。 a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model.
已发布 PubMed:杏仁(李子d。a。webb)种子的解剖和细胞壁多糖。 Anatomy and cell wall polysaccharides of almond (Prunus dulcis D. A. Webb) seeds.
已发布 PubMed: 转化和未转化的结肠细胞的早期和晚期凋亡事件与细胞内酸化无关。 Early and late apoptosis events in human transformed and non-transformed colonocytes are independent on intracellular acidification.
已发布 PubMed:amp激活的蛋白激酶在控制食物摄入中发挥作用。 AMP-activated protein kinase plays a role in the control of food intake.
已发布 PubMed:β-乳球蛋白-果胶膜稳定液滴的水包油乳液的制备和表征。 Production and characterization of oil-in-water emulsions containing droplets stabilized by beta-lactoglobulin-pectin membranes.
已发布 PubMed:二苯甲酰甲烷对食品衍生的杂环胺诱变剂致突变性的抑制作用。 Inhibitory effect of dibenzoylmethane on mutagenicity of food-derived heterocyclic amine mutagens.
已发布 PubMed:姜黄素及其天然类似物对煮熟食品中杂环胺的遗传毒性的抑制作用。 Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food.
已发布 PubMed:gdp状态的微管蛋白-秋水仙碱复合物的聚合和钙结合。 Polymerization and calcium binding of the tubulin-colchicine complex in the GDP state.
已发布 PubMed:(-)-表没食子儿茶素没食子酸酯对突变的抑制作用 Inhibitory effects of (-)-epigallocatechin gallate on the mutation, dna链断裂 DNA strand cleavage, 和由杂环胺形成的dna加合物。 and DNA adduct formation by heterocyclic amines.
已发布 PubMed:恶性疟原虫富含组氨酸蛋白中和毒性血红素2。 Neutralization of toxic heme by Plasmodium falciparum histidine-rich protein 2.
已发布 PubMed:利用福林-卡塔尔酚试剂检测某些含氮化合物。 Utilization of Folin-Ciocalteu phenol reagent for the detection of certain nitrogen compounds.
已发布 PubMed:15-脱氧-delta12促进pc-12细胞突突延伸过程中p38丝裂原活化蛋白激酶和活化蛋白-1的活化 Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-前列腺素j2。 14-prostaglandin J2.
已发布 PubMed:一种基于组氨酸标签的固定化方法,用于载脂蛋白的制备和重组。 A His-tag based immobilization method for the preparation and reconstitution of apoflavoproteins.
已发布 PubMed:田间条件下溶菌剂咪唑磺隆的迁移率和降解。 Mobility and degradation of the herbicide imazosulfuron in lysimeters under field conditions.
已发布 PubMed:柠檬cdna中的铜/超氧化物歧化酶和酶稳定性。 Copper/zinc-superoxide dismutase from lemon cDNA and enzyme stability.
已发布 PubMed:杀虫剂前氯唑的体外和体内抗雄激素作用。 Antiandrogenic effects in vitro and in vivo of the fungicide prochloraz.
已发布 PubMed:n-乙酰基-glu-p-1的反应活性和选择性 Reactivity and selectivity of the N-acetyl-Glu-P-1, n-乙酰基-glu-p-2 N-acetyl-Glu-P-2, 正乙酰基 N-acetyl-MeIQx, 和n-乙酰基-iqx氮离子 and N-acetyl-IQx nitrenium ions: 与碳环正芳基氮鎓离子的比较。 comparison to carbocyclic N-arylnitrenium ions.
已发布 PubMed:小鼠黑皮质素受体上的黑皮质素四肽ac-his-dphe-arg-trp-nh(2)的结构-活性关系。 1.修改他的位置。 Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH(2) at the mouse melanocortin receptors. 1. Modifications at the His position.
已发布 PubMed:纸莎草主要cdna中铜/锌超氧化物歧化酶的特性和酶稳定性。 Characterization of copper/zinc-superoxide dismutase from Pagrus major cDNA and enzyme stability.
已发布 PubMed:纳豆(发酵食品)和纳豆芽孢杆菌分离物与致癌致癌杂环胺的结合活性。 Binding activity of natto (a fermented food) and Bacillus natto isolates to mutagenic-carcinogenic heterocyclic amines.
已发布 PubMed:液相色谱和串联质谱法鉴定虹鳟鱼中前敌百虫的主要代谢物。 Identification of the major metabolites of prochloraz in rainbow trout by liquid chromatography and tandem mass spectrometry.
已发布 PubMed:橄榄果细胞壁 Olive fruit cell wall: 在成熟过程中果胶多糖的降解。 degradation of pectic polysaccharides during ripening.
已发布 PubMed:[某些食物成分对黄曲霉毒素b1代谢的干扰的体外研究]。 [In vitro study of the interference of certain food components with the metabolism of aflatoxin B1].
已发布 PubMed:[各种食物成分对黄曲霉毒素b1代谢的抑制作用的体内研究]。 [In vivo studies of the inhbitory effect of various food components on aflatoxin B1 metabolism].
已发布 PubMed:柠檬生产中使用的化学产品对霍乱弧菌o1 tox +的作用。 Action against Vibrio cholerae O1 Tox+ of chemical products used in the lemon production.
已发布 PubMed:再谈组胺鱼中毒。 Histamine fish poisoning revisited.
已发布 PubMed:含有通过不同表面活性剂稳定的脂肪小球的凝乳酶凝胶的动态流变学。 Dynamic rheology of renneted milk gels containing fat globules stabilized with different surfactants.
已发布 PubMed:对咪唑啉i(2)结合位点具有高亲和力的新型化合物的高吞噬作用。 Hyperphagic effect of novel compounds with high affinity for imidazoline I(2) binding sites.
已发布 PubMed:酪蛋白酸盐稳定的乳液的原动力絮凝 Orthokinetic flocculation of caseinate-stabilized emulsions: 钙浓度的影响 influence of calcium concentration, 剪切率 shear rate, 和蛋白质含量。 and protein content.
已发布 PubMed:木瓜铜/锌超氧化物歧化酶的二聚单体平衡的表征及其通过单个氨基酸突变的平衡位移。 Characterization of the dimer-monomer equilibrium of the papaya Copper/Zinc superoxide dismutase and its equilibrium shift by a single amino acid mutation.
已发布 PubMed:丙草胺在不同土壤中的吸附行为 Sorption behavior of prochloraz in different soils.
已发布 PubMed:酚醛树脂 Phenolics: 杂环胺诱导的致癌作用的阻断剂。 blocking agents for heterocyclic amine-induced carcinogenesis.
已发布 PubMed: 的玫瑰茄(芙蓉sabdariffa sabdariffa linn)的影响 , 泰国药用植物 a Thai medicinal plant, 鼠 歐洲海濱草中各种已知诱变剂的致突变性以及结肠致癌物甲氧甲烷和2-氨基-1-甲基-6-苯基咪唑并引发异常隐窝灶的形成[4 on the mutagenicity of various known mutagens in Salmonella typhimurium and on formation of aberrant crypt foci induced by the colon carcinogens azoxymethane and 2-amino-1-methyl-6-phenylimidazo[4,f344大鼠中的5-b]吡啶。 5-b]pyridine in F344 rats.
已发布 PubMed:维生素和相关化合物对熟食中遗传毒性杂环胺的抗诱变作用和可能的作用机理。 Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food.
已发布 PubMed:g-组黄曲霉毒素的酶促形成以及g-和b-组黄曲霉毒素之间的生物合成关系。 Enzymatic formation of G-group aflatoxins and biosynthetic relationship between G- and B-group aflatoxins.
已发布 PubMed:The "处方药 prescription-to-OTC 开关 switch" 运动 movement. its it Its 效果 影响 effects on 抗真菌药 anti真菌的 fungal 阴道炎 vaginitis 准备工作 制备 preparations.
已发布 PubMed:咪唑立滨和霉酚酸酯。 Mizoribine and mycophenolate mofetil.
已发布 PubMed:醇与组胺的相互作用。 Alcohol-histamine interactions.
已发布 PubMed:用于磷脂产品质量控制的毛细管电泳方法。 Capillary electrophoretic method for quality control of phospholipid products.
已发布 PubMed:各种茶提取物对源自诱变剂代谢的超氧化物的清除作用。 Scavenging effect of various tea extracts on superoxide derived from the metabolism of mutagens.
已发布 PubMed:硝基咪唑放射增敏剂对食蟹猴的毒性。 Nitro-imidazole radiosensitizer-induced toxicity in cynomolgus monkeys.
已发布 PubMed:腌青橄榄中果胶多糖的降解。 Degradation of pectic polysaccharides in pickled green olives.
已发布 PubMed:煮熟的诱变剂对精确切割大鼠非计划性dna合成的影响 Effect of some cooked food mutagens on unscheduled DNA synthesis in cultured precision-cut rat, 小鼠和 类肝脏切片。 mouse and human liver slices.
已发布 PubMed:咪唑基化合物2-乙酰基-4-四羟基丁基咪唑抑制了成熟t细胞从胸腺的迁移。 Emigration of mature T cells from the thymus is inhibited by the imidazole-based compound 2-acetyl-4-tetrahydroxybutylimidazole.
已发布 PubMed:评估鸡g平滑肌肌原纤维和结缔组织蛋白的质量。 Assessment of the protein quality of the smooth muscle myofibrillar and connective tissue proteins of chicken gizzard.
已发布 PubMed:比较抗转移化合物imh [trans-rucl4(dmso)im](nami-a)对节螺藻大鼠和小鼠mca乳腺癌的作用。 Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice.
已发布 PubMed:味mis乳酸菌对杂环胺的结合 Binding of heterocyclic amines by lactic acid bacteria from miso, 发酵的日本料理。 a fermented Japanese food.
已发布 PubMed:免疫调节化合物2-乙酰基-4-四羟基丁基咪唑引起非淋巴组织中的淋巴细胞隔离。 The immunomodulatory compound 2-acetyl-4-tetrahydroxybutyl imidazole causes sequestration of lymphocytes in non-lymphoid tissues.
已发布 PubMed:鱼和肉制品中的极性和非极性杂环胺及其相应的残渣。 Polar and non-polar heterocyclic amines in cooked fish and meat products and their corresponding pan residues.
已发布 PubMed:通过在大鼠中低剂量联合施用食物衍生的杂环胺来增强肝癌的发生。 Enhancement of hepatocarcinogenesis by combined administration of food-derived heterocyclic amines at low doses in the rat.
已发布 PubMed:花生壳甲醇提取物的抗突变作用。 Antimutagenic effect of methanolic extracts from peanut hulls.
已发布 PubMed:毛细管电泳法测定火焰烤鱼肉饼中的杂环胺 Determination of heterocyclic amines in flame-grilled fish patty by capillary electrophoresis.
已发布 PubMed:花斑癣的诊治。 Diagnosis and treatment of tinea versicolor.
已发布 PubMed:小鼠血管内皮肉瘤和glu-p-1诱导的肝肿瘤中 类c-ha-ras转基因的罕见激活。 Rare activation of the human c-Ha-ras transgene of mice in hemangioendothelial sarcomas and liver tumors induced by Glu-P-1.
已发布 PubMed:2-氨基-1-甲基-6-苯基咪唑的晶体结构与理论比较[4] Comparison of crystal structure and theory for 2-amino-1-methyl-6-phenylimidazo[4,5-b]吡啶。 5-b]pyridine.
已发布 PubMed:咖啡因和相关甲基黄嘌呤在抗坏血酸和多酚驱动的芬顿型氧化中的氧化。 Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations.
已发布 PubMed:抗诱变活性与各种茶的主要成分之间的关​​系。 Relationship between antimutagenic activity and major components of various teas.
已发布 PubMed:nardostachyos radix et rhizoma的挥发油通过清除h9c2心肌中的活性氧和akt活化来抑制氧化应激诱导的细胞损伤。 The immunosuppressive compound 2-acetyl-4-tetrahydroxybutyl imidazole inhibits the allogeneic mixed lymphocyte reaction by sequestration of a recirculating subpopulation of T cells.
已发布 PubMed:scid-hu小鼠可作为免疫毒理学风险评估的工具 The SCID-hu mouse as a tool in immunotoxicological risk assessment: 2-乙酰基-4(5)-四羟基丁基咪唑(thi)和二正丁基二氯化锡(dbtc)对scid-hu小鼠胸腺的影响。 effects of 2-acetyl-4(5)-tetrahydroxybutyl-imidazole (THI) and di-n-butyltin dichloride (DBTC) on the human thymus in SCID-hu mice.
已发布 PubMed:维索卡汀 Visoltricin, 镰孢镰刀菌生产的新型生物活性化合物。 a novel biologically active compound produced by Fusarium tricinctum.
已发布 PubMed:吡哆醇补充可保护小鼠免受2-乙酰-4-四羟基丁咪唑(thi)诱导的接触性超敏反应的抑制 Pyridoxine supplementation protects mice from suppression of contact hypersensitivity induced by 2-acetyl-4-tetrahydroxybutylimidazole (THI), 紫外线b (280-320 nm) ultraviolet B radiation (280-320 nm), 或顺式尿烷酸。 or cis-urocanic acid.
已发布 PubMed:hca诱导的肿瘤的遗传改变。 Genetic alterations in HCA-induced tumors.
已发布 PubMed:食品中的致癌物 Carcinogens in foods: 杂环胺与癌症和心脏病。 heterocyclic amines and cancer and heart disease.
已发布 PubMed:脂肪饮食对雪貂肝脏微粒体氧合的影响 Effect of high fat diet on liver microsomal oxygenations in ferret.
已发布 PubMed:氟铝酞菁的光化学性质 The photochemical properties of fluoroaluminum phthalocyanine.
已发布 PubMed:捆绑 Binding 属性 properties of 乳酸 lactic acid 菌 bacteria from '闲着 Idly' 向 朝 towards 食物传播的 food-borne 诱变剂 mutagens.
已发布 PubMed:咪唑开环n7-(2-羟乙基)鸟苷单克隆抗体的环氧乙烷-dna加合物检测的各种免疫化学分析的Comparison of various immunochemical assays for the detection of ethylene oxide-DNA adducts with monoclonal antibodies against imidazole ring-opened N7-(2-hydroxyethyl)guanosine: 在生物监测研究中的应用。 application in a biological monitoring study.
已发布 PubMed:着色添加剂焦糖色iii的免疫毒性;审查食品添加剂安全性评估中的复合物问题。 Immunotoxicity of the colour additive caramel colour III; a review on complicated issues in the safety evaluation of a food additive.
已发布 PubMed:cu2 +介导的糖化胰岛素中组氨酸残基的位点特异性氧化。 Site-specific oxidation of histidine residues in glycated insulin mediated by Cu2+.
已发布 PubMed: 和大鼠肝脏微粒体对n-羟基杂环胺的葡萄糖醛酸化作用 Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
已发布 PubMed:蒽抗突变潜力的评估 Evaluation of the antimutagenic potential of anthracene: 体外和离体研究。 in vitro and ex vivo studies.
已发布 PubMed:固定化金属离子亲和色谱。 Immobilized metal ion affinity chromatography.
已发布 PubMed:组氨酸21在白喉毒素催化中不起主要作用。 Histidine 21 does not play a major role in diphtheria toxin catalysis.
已发布 PubMed:干扰d-木糖异构酶中的金属位点。 -220突变对酶稳定性的影响。 Perturbing the metal site in D-xylose isomerase. Effect of mutations of His-220 on enzyme stability.
已发布 PubMed:亚慢性暴露于焦糖色iii对小鼠免疫系统的影响。 Effects of subchronic exposure to Caramel Colour III on the immune system in mice.
已发布 PubMed:歐洲海濱草中glu-p-1的突变谱 Mutation spectra of Glu-P-1 in Salmonella: 诱导热点移码和特定地点的碱基替代。 induction of hotspot frameshifts and site-specific base substitutions.
已发布 PubMed:所选牛肉调味料中杂环芳香胺的含量。 Heterocyclic aromatic amine content of selected beef flavors.
已发布 PubMed:通过化学修饰,含有来自肠膜白斑隐球菌的右旋糖核酸酶的第二个必需羧基的活性位点肽。 An active-site peptide containing the second essential carboxyl group of dextransucrase from Leuconostoc mesenteroides by chemical modifications.
已发布 PubMed:酸化红细胞裂解液中的血红蛋白变性和铁释放-红细胞内疟疾寄生虫的铁可能来源。 Hemoglobin denaturation and iron release in acidified red blood cell lysate--a possible source of iron for intraerythrocytic malaria parasites.
已发布 PubMed:2-氨基-1-甲基-6-苯基咪唑的直接葡萄糖醛酸化作用[4 The direct glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]吡啶(phip)由 和兔的肝微粒体产生。 5-b] pyridine (PhIP) by human and rabbit liver microsomes.
已发布 PubMed:食物中的致癌因素与结肠癌的发展有关。 Carcinogenic factors in food with relevance to colon cancer development.
已发布 PubMed:益康唑通过细胞色素p-450抑制以外的机制抑制毒胡萝卜素诱导的血小板钙内流。 Econazole inhibits thapsigargin-induced platelet calcium influx by mechanisms other than cytochrome P-450 inhibition.
已发布 PubMed:β-淀粉酶在大肠杆菌中的表达和突变 Expression and mutation of soybean beta-amylase in Escherichia coli.
已发布 PubMed:焦糖色素iii的免疫毒性作用 Immunotoxic effects of the color additive caramel color III: 大鼠免疫功能研究。 immune function studies in rats.
已发布 PubMed:焦糖色素iii对免疫系统的影响 Effects of the colour additive caramel colour III on the immune system: 与 类志愿者进行的研究。 a study with human volunteers.
已发布 PubMed:2-乙酰基-4-四羟基丁基咪唑(thi)对大鼠胸腺的影响 Effects of 2-acetyl-4-tetrahydroxybutyl imidazole (THI) on the thymus of rats.
已发布 PubMed:通过铜(ii)催化的葡糖苷的自氧化,选择性氧化蛋白质或肽中的组氨酸残基。 Selective oxidation of histidine residues in proteins or peptides through the copper(II)-catalysed autoxidation of glucosone.
已发布 PubMed:口服给药后,咪唑类杀菌剂(丙草胺)在大鼠体内的代谢。 Metabolism of an imidazole fungicide (prochloraz) in the rat after oral administration.
已发布 PubMed:使用木炭-氧化铝色谱柱的自动化程序,用于测定谷物中的滴虫毒素。 Automation of a clean-up procedure for determination of trichothecenes in cereals using a charcoal-alumina column.
已发布 PubMed:口服2-乙酰基-4-四羟基丁基咪唑(thi)预防非肥胖糖尿病(点头)小鼠自发性和环磷酰胺诱导的糖尿病 Prevention of spontaneous and cyclophosphamide-induced diabetes in non-obese diabetic (NOD) mice with oral 2-acetyl-4-tetrahydroxybutylimidazole (THI), 焦糖色素的成分iii。 a component of caramel colouring III.
已发布 PubMed:焦糖色iii对血液淋巴细胞数量的影响 Effects of Caramel Colour III on the number of blood lymphocytes: 一项关于焦糖色iii免疫毒性的 类研究,并将结果与​​大鼠研究数据进行了比较。 a human study on Caramel Colour III immunotoxicity and a comparison of the results with data from rat studies.
已发布 PubMed:(-)-表没食子儿茶素没食子酸酯抑制致癌物的遗传毒性。 Suppression of genotoxicity of carcinogens by (-)-epigallocatechin gallate.
已发布 PubMed:淋巴细胞产生和迁移在2-乙酰基-4-四羟基丁基咪唑引起的淋巴细胞减少中的作用。 The role of lymphocyte production and migration in the lymphopenia caused by 2-acetyl-4-tetrahydroxybutyl imidazole.
已发布 PubMed:亚硝酸盐增强歐洲海濱草系统对智商和meiq的致突变性。 Enhancement of the mutagenicity of IQ and MeIQ by nitrite in the Salmonella system.
已发布 PubMed:4-氨基联苯与食品热解产物的致癌性Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, 谷蛋白1 Glu-P-1, iq IQ, hip PhIP, 新生b6c3f1雄性小鼠体内的meiqx和meiqx。 and MeIQx in the neonatal B6C3F1 male mouse.
已发布 PubMed:色添加剂焦糖色iii和2-乙酰基-4(5)-四羟基丁基咪唑(thi)对大鼠免疫系统的影响。 Effects of the color additive caramel color III and 2-acetyl-4(5)-tetrahydroxybutylimidazole (THI) on the immune system of rats.
已发布 PubMed:食品中诱变/致癌的杂环芳香胺的定量分析。 Quantitation of mutagenic/carcinogenic heterocyclic aromatic amines in food products.
已发布 PubMed:组氨酸对肌质网脂质过氧化的影响 Influence of histidine on lipid peroxidation in sarcoplasmic reticulum.
已发布 PubMed:从氨基酸和糖中获得的美拉德褐变产品的抗诱变作用。 Antimutagenic effect of Maillard browning products obtained from amino acids and sugars.
已发布 PubMed:交感橙花系统参与小鼠膳食诱导的生热作用。 The involvement of the sympathetic nervous system in meal-induced thermogenesis in mice.
已发布 PubMed: 肝和结肠对致癌杂环芳香胺的代谢活化作用。 Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
已发布 PubMed:2-乙酰基-4-四羟基丁基咪唑(thi)在大鼠中的免疫抑制作用。 Immunosuppressive effects of 2-acetyl-4-tetrahydroxybutyl imidazole (THI) in the rat.
已发布 PubMed:咪唑抗真菌药的体外作用 In vitro effects of an imidazole antifungal, 丙草胺 Prochloraz, 微粒体细胞色素p-450的光谱和催化性能 on spectral and catalytic properties of microsomal cytochromes P-450.
已发布 PubMed:数值方法从初始速度数据和半经验程序分析ph分布,以利用pk和电离热识别酶的催化残基。 Numerical method to analyze pH-profile from initial velocity data and semi-empirical procedure to identify catalytic residues of enzymes using pK and heat of ionization.
已发布 PubMed:饮食中给予杂环胺后,在f344大鼠中心脏dna加合物的形成。 The formation of heart DNA adducts in F344 rat following dietary administration of heterocyclic amines.
已发布 PubMed:解析亲和色谱法测定钙与酪蛋白亚胶束相互作用的特性。 Characteristics of the interaction of calcium with casein submicelles as determined by analytical affinity chromatography.
已发布 PubMed:铜(ii)和l-抗坏血酸盐对血管紧张素i的定点氧化 Site-specific oxidation of angiotensin I by copper(II) and L-ascorbate: 组氨酸残基转化为2-咪唑啉酮。 conversion of histidine residues to 2-imidazolones.
已发布 PubMed:hr-13268d的体内和体外活性 The in vivo and in vitro activity of AHR-13268D, 一种新的抗过敏/抗组胺药。 a new antiallergic/antihistaminic agent.
已发布 PubMed:抗突变性和中国奶酪中的乳酸菌与诱变热解产物的结合。 Antimutagenicity and binding of lactic acid bacteria from a Chinese cheese to mutagenic pyrolyzates.
已发布 PubMed:定量食品中诱变杂环芳香胺的简单方法。 Simple methods for quantifying mutagenic heterocyclic aromatic amines in food products.
已发布 PubMed:15N 核 nuclear 磁性 magnetic 谐振 resonance 学习 studies on the 互变异构 tautomerism of 8-hydroxy-2'-deoxy鸟苷 guanosine, 8-羟基鸟苷 8-hydroxyguanosine, 和其他c8取代的鸟嘌呤核苷。 and other C8-substituted guanine nucleosides.
已发布 PubMed:1-甲基组氨酸及其类似物与铜(ii)/抗坏血酸依赖的氧化还原系统的高位点特异性氧合。 Highly site-specific oxygenation of 1-methylhistidine and its analogue with a copper (II)/ascorbate-dependent redox system.
已发布 PubMed:2-氨基-3-甲基咪唑的出现[4 Occurrence of 2-amino-3-methylimidazo[4,5-f]喹啉(iq) 5-f]quinoline (IQ), 2-氨基-6-甲基联吡啶[1 2-amino-6-methyldipyrido[1,2-a 2-a:3',2'-d]imidazole (谷蛋白1 Glu-P-1) and other 杂环的 heterocyclic amine 诱变剂 mutagens inoil of 烧焦的 charred 蛋 egg 蛋黄 yolk (然语 ranyu).
已发布 PubMed:15n和1h nmr表征红螺 藻细胞色素c2中ph依赖的构象异质性。 Characterization of pH-dependent conformational heterogeneity in Rhodospirillum rubrum cytochrome c2 using 15N and 1H NMR.
已发布 PubMed: 在鼠 歐洲海濱草ta 1535 / psk1002中,通过umu umu基因应答检测到的 类肝微粒体细胞色素p-450酶参与了致癌物的生物活化。
已发布 PubMed:苯并蒽醌 Benzanthrone: 肝微粒体细胞色素p-450的新底物。 a new substrate for hepatic microsomal cytochrome P-450.
已发布 PubMed:l-抗坏血酸介导的n-乙酰基组胺的单加氧作用。 Monooxygenation of N-acetylhistamine mediated by L-ascorbate.
已发布 PubMed:食物致癌物2-氨基-3-甲基咪唑[4]优先诱导大鼠肝p450 i蛋白 Preferential induction of the rat hepatic P450 I proteins by the food carcinogen 2-amino-3-methyl-imidazo[4,5-f]喹啉。 5-f]quinoline.
已发布 PubMed:溶菌剂对体外培养的 疟原虫恶性疟原虫的影响 Effects of lysosomotropic detergents on the human malarial parasite Plasmodium falciparum in in vitro culture.
已发布 PubMed:链脲佐菌素治疗大鼠的肝制剂对化学致癌物的代谢活化作用。 Metabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats.
已发布 PubMed:抗突变剂蒽黄酮酸诱导大鼠肝细胞色素p-450 i蛋白的表达。 Induction of rat hepatic cytochrome P-450 I proteins by the antimutagen anthraflavic acid.
已发布 PubMed:糖基化产物在糖尿病并发症中的作用 Role of advanced glycosylation products in complications of diabetes.
已发布 PubMed:血栓烷合成抑制剂和餐后空肠毛细血管交换能力。 Thromboxane synthesis inhibitors and postprandial jejunal capillary exchange capacity.
已发布 PubMed:咪唑烷的合成及诱变活性。杂环芳基胺和硝基芳烃的遗传毒性机理研究。 Synthesis and mutagenic activity of nitro-imidazoarenes. A study on the mechanism of the genotoxicity of heterocyclic arylamines and nitroarenes.
已发布 PubMed:肝细胞原代培养/ dna修复试验中杂环胺热解和烹饪产物的遗传毒性的种类和性别差异 Species and sex differences in genotoxicity of heterocyclic amine pyrolysis and cooking products in the hepatocyte primary culture/DNA repair test using rat, 老鼠 mouse, 和仓鼠肝细胞。 and hamster hepatocytes.
已发布 PubMed:评价歧视性刺激的拮抗剂和苯环利定的缓解率。 Evaluation of antagonists of the discriminative stimulus and response rate effects of phencyclidine.
已发布 PubMed:酮康唑的临床药代动力学。 Clinical pharmacokinetics of ketoconazole.
已发布 PubMed:高效液相色谱法检测伍斯特郡酱汁中致癌的谷氨酸热解产物。 Detection of carcinogenic glutamic acid pyrolysis products in Worcestershire sauce by high-performance liquid chromatography.
已发布 PubMed:九种诱变氨基酸裂解液的两阶段小鼠皮肤模型中的启动活性 Initiating activity in a two-stage mouse skin model of nine mutagenic pyrolysates of amino acids, 大豆球蛋白和蛋白质食品。 soybean globulin and proteinaceous food.
已发布 PubMed:前列腺素h合酶依赖性iq型杂环芳香胺的诱变激活。 Prostaglandin H synthase-dependent mutagenic activation of heterocyclic aromatic amines of the IQ-type.
已发布 PubMed:关于冷冻干燥和煮熟的牛肉中存在的血红素色素性质的说明。 A note on the nature of the haematin pigments present in freeze dried and cooked beef.
已发布 PubMed:金属蛋白相互作用。 Metal protein interactions.
已发布 PubMed:[ 类肠道菌群对热解产物代谢活化的作用]。 [Th role of human intestinal flora on the metabolic activation of pyrolysis products].
已发布 PubMed:氨化干草中毒的病因。 Etiology of ammoniated hay toxicosis.
已发布 PubMed:熟食中杂环胺对小鼠和大鼠的致癌性。 Carcinogenicity in mice and rats of heterocyclic amines in cooked foods.
已发布 PubMed:培养仓鼠肺细胞中杂环胺的诱变活性 Mutagenic activities of heterocyclic amines in Chinese hamster lung cells in culture.
已发布 PubMed:食物中热解突变的代谢方面。 Metabolic aspects of pyrolysis mutagens in food.
已发布 PubMed:吲哚啉的硝基和甲基-硝基衍生物的构效关系 Structure-activity relationships of nitro and methyl-nitro derivatives of indoline, 吲哚 indole, 鼠 歐洲海濱草中的吲唑和苯并咪唑。 indazole and benzimidazole in Salmonella typhimurium.
已发布 PubMed:血栓烷的合成抑制和餐后肠道充血和氧合。 Thromboxane synthesis inhibition and postprandial intestinal hyperemia and oxygenation.
已发布 PubMed:乙醇预处理后,增强氨基酸热解产物和烧烤食品中的几种诱变剂对肝细胞的遗传毒性。 Enhancement of hepatocellular genotoxicity of several mutagens from amino acid pyrolysates and broiled foods following ethanol pretreatment.
已发布 PubMed:食物摄入对组胺尿排泄的影响 Effect of food intake on urinary excretions of histamine, 正牛头甲基组胺 N tau-methylhistamine, 咪唑乙酸及其在 和小鼠中的结合物。 imidazole acetic acid and its conjugate(s) in humans and mice.
已发布 PubMed:药理学评论 Pharmacologic review: 酮康唑治疗足癣和甲癣的文献综述。 a review of the literature of ketoconazole therapy in the treatment of tinea pedis and onychomycosis.
已发布 PubMed:肠癌的诱导 Induction of cancers in the intestine, 通过从谷氨酸热解物中摄取诱变剂来使大鼠肝脏和其他各种器官。 liver and various other organs of rats by feeding mutagens from glutamic acid pyrolysate.
已发布 PubMed:双嘧啶衍生物的生化效应[1] Biochemical effects of some derivatives of dipyrido[1,2-a 2-a:3,'2'-d]imidazole 有关 related to 蛋白 protein 裂解物 裂解物 pyrolysates on rat 肝 liver 微粒体 microsomes.
已发布 PubMed:食物中与癌症原因相关的可能的遗传毒性致癌物。 Possible genotoxic carcinogens in foods in relation to cancer causation.
已发布 PubMed:酮康唑。 Ketoconazole.
已发布 PubMed:饲喂不易消化的植物细胞壁成分的大鼠盲肠微生物的代谢谱。 Metabolic profile of caecal micro-organisms from rats fed indigestible plant cell-wall components.
已发布 PubMed:在煮猪肉提取物中形成诱变剂。 Formation of mutagens in boiled pork extract.
已发布 PubMed:对处理过的葡萄柚中咪唑啉残留量分析的改进。 A modification of imazalil residue analysis in treated grapefruit.
已发布 PubMed:[各种物质对氮氧化物和亚硝酸盐的阻断]。 [Blockade of nitrogen oxide and nitrites by various substances].
已发布 PubMed:生物学活性剂对le蛇摄食反应的影响 [Effect of biologically active agents on the feeding response of Dileptus anser].
已发布 PubMed:过氧化脂质与组氨酸残基类似物之间的反应 Reactions between peroxidizing lipids and histidyl residue analogues: 4-甲基咪唑增强脂质氧化和褐变。 enhancement of lipid oxidation and browning by 4-methylimidazole.
已发布 PubMed:肉制品中添加色素的定性测试。 Qualitative tests for added coloring matter in meat products.
已发布 PubMed:钙激活的青蛙皮肤肌肉纤维的张力。依赖于三磷酸腺苷镁的浓度。 Calcium-activated tension of skinned muscle fibers of the frog. Dependence on magnesium adenosine triphosphate concentration.
 
笔记 Notes:
分离。从扁豆种子(扁豆)的种子。也存在于其他豆科植物的种子中 Isol. from the seeds of Lens culinaris (lentil). Also present in the seeds of other legumes: 巨大型单眼巨瘤(马匹克) Macrotyloma uniflorum (horse gram), psophocarpus tetragonolobus(四棱豆) , gna豆(绿豆) Vigna radiata (mung bean) 咪唑是5元平面环 Imidazole is a 5-membered planar ring, 溶于水和其他极性溶剂。它以两种等效的互变异构形式存在,因为氢原子可以位于两个氮原子中的任何一个上。咪唑是一种高极性化合物 which is soluble in water and other polar solvents. It exists in two equivalent tautomeric forms because the hydrogen atom can be located on either of the two nitrogen atoms. Imidazole is a highly polar compound, 由3.61d的计算偶极子证明 as evidenced by a calculated dipole of 3.61D, 完全溶于水。由于存在六重电子,该化合物被分类为芳香族 and is entirely soluble in water. The compound is classified as aromatic due to the presence of a sextet of ?-electrons, 磷酸氢二钾磷酸氢二钾磷酸氢二钾磷酸氢二钾磷酸氢二钾单磷酸氢二氢磷酸氢二钾磷酸氢二钾磷酸氢二钾盐磷酸 consisting of a pair of electrons from the protonated nitrogen atom and one from each of the remaining four atoms of the ring.; Imidazole is a heterocyclic aromatic organic compound. It is further classified as an alkaloid. Imidazole refers to the parent compound C3H4N2, 2-甲氧基-1-(戊氧基)-4-丙烯基-异丁香酚戊醚2-甲氧基-1-(戊氧基)-4-(1-丙烯基)苯2-甲氧基-1-(戊氧基)-4-(1-丙烯基) )-苯2-甲氧基-1-戊氧基-4-((e)-丙-1-烯基)苯2-甲氧基-1-戊氧基-4-[(e)-丙-1-烯基]苯1-戊氧基-2-甲氧基-4-丙烯基苯1-戊氧基-2-甲氧基-4-丙烯基苯2-戊氧基-5-丙-1-烯基苯甲醚2-戊氧基-5-丙-1-烯基苯甲醚 while imidazoles are a class of heterocycles with similar ring structure but varying substituents. This ring system is present in important biological building blocks such as histidine and histamine. Imidazole can act as a base and as a weak acid. Imidazole exists in two tautomeric forms with the hydrogen atom moving between the two nitrogens. Many drugs contain an imidazole ring, 如抗真菌药和硝基咪唑。咪唑是5元平面环,可溶于水和极性溶剂。咪唑是碱和优良的亲核试剂。它在nh氮处反应 such as antifungal drugs and nitroimidazole. Imidazole is a 5 membered planar ring which is soluble in water and polar solvents. Imidazole is a base and an excellent nucleophile. It reacts at the NH nitrogen, 攻击烷基化和酰化化合物。它不是特别容易受到碳原子上的亲电攻击 attacking alkylating and acylating compounds. It is not particularly susceptible to electrophilic attacks at the carbon atoms, 这些反应大多数都是取代基,可以保持芳香性完整。从共振结构可以看出,碳2是最有可能亲核攻击它的碳 and most of these reactions are substitutions that keep the aromaticity intact. One can see from the resonance structure that the carbon-2 is the carbon most likely to have a nucleophile attack it, 通过下一代测序技术评估了与双低油菜籽(甘蓝型油菜)两个不同发育阶段相关的根细菌群落的变化。 but in general nucleophilic substitutions are difficult with imidazole. Imidazole is incorporated into many important biological molecules. The most obvious is the amino acid histidine, 亚当·迈克尔(Adam michael)曾说过“这种有机迷迭香精油是突尼斯的原料,比西班牙的原料更好,而且掺假更少。迷迭香精油的蒸馏最早由arnoldus villanovus于13世纪描述。他一起蒸馏迷迭香和松节油。在接下来的三四百年中,一种类似的产品被称为饥饿水,被广泛用作香水和嫩肤剂。通过花朵和叶子的蒸汽蒸馏生产的 which has an imidazole side chain. histidine is present in many proteins and enzymes and plays a vital part in the structure and binding functions of hemoglobin.; Imidazole is an organic compound with the formula C3H4N2. This aromatic heterocyclic is classified as an alkaloid. Imidazole refers to the parent compound whereas imidazoles are a class of heterocycles with similar ring structure but varying substituents. This ring system is present in important biological building blocks such as histidine, 以及相关的激素组胺。咪唑可以用作碱和弱酸。许多药物都含有咪唑环 and the related hormone histamine. Imidazole can serve as a base and as a weak acid. Many drugs contain an imidazole ring, 如抗真菌药和硝基咪唑。咪唑被掺入许多重要的生物分子中。最普遍的是氨基酸组氨酸 such as antifungal drugs and nitroimidazole.; Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, 有咪唑侧链组氨酸存在于许多蛋白质和酶中,在血红蛋白的结构和结合功能中起着至关重要的作用。组氨酸可以脱羧成组胺 which has an imidazole side chain. Histidine is present in many proteins and enzymes and plays a vital part in the structure and binding functions of hemoglobin. Histidine can be decarboxylated to histamine, 这也是一种常见的生物化合物。它是引起荨麻疹的毒素的组成部分 which is also a common biological compound. It is a component of the toxin that causes urticaria, 这是过敏性荨麻疹的别称。组氨酸和组胺的关系如下所示 which is another name for allergic hives. The relationship between histidine and histamine are shown below:;这是一种常规方法,能够为取代的咪唑提供良好的收率。它本质上是对称为debus-radziszewski咪唑合成的debus方法的改编。起始原料是取代的乙二醛 ; This is a general method which is able to give good yields for substituted imidazoles. It is essentially an adaptation of the Debus method called the Debus-Radziszewski imidazole synthesis. The starting materials are substituted glyoxal, aldehyde, amine, 和氨水或铵盐。 and ammonia or an ammonium salt.
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