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类别 Category:special dietary and nutritional additives
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 熔点 Melting Point: | 109.00 to 110.00 °C. @ 760.00 mm 汞 Hg
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| 沸点 Boiling Point: | 407.00 to 408.00 °C. @ 760.00 mm 汞 Hg (est)
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| 闪点 Flash Point: | 392.00 °F. tcc TCC ( 200.00 °C. )
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| logp（o / w） logP (o/w): | -0.696（est） -0.696 (est) |
| 溶于 Soluble in: |
| | 水 water, 2.429e + 005 mg / l @ 25°c（est） 2.429e+005 mg/L @ 25 °C (est) |
| 类似物品 Similar Items:note |
| 乙酰 acetyl-dextro,左旋色氨酸 laevo-tryptophan |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
| 首选sds SDS : 视图 View |
| 欧洲信息 European information : |
| 最重要的危害 Most important hazard(s): | | 无-找不到。 None - None found. |
S 02 - 保持 Keep out of the 达到 reach of 孩子们 children.
S 22 - do Do not 呼吸 breath dust.
S 24/25 - 避免 Avoid contact with skin and 眼睛 eyes.
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| 危害识别 Hazards identification |
| |
| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
| |
| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
腹腔内小鼠 intraperitoneal-老鼠 mouse LD50 400 mg/kg
国民 nat National 技术 Technical Information 服务 Service. 卷 Vol. AD691-490
静脉老鼠 intravenous-老鼠 mouse LD50 3800 mg/kg
BRAIN and AND 覆盖物 COVERINGS: 来自cns CNS特定区域的录音
肺 LUNGS, 胸部 THORAX, 或呼吸 OR RESPIRATION: 其他变化 OTHER CHANGES
行为的 BEHAVIORAL: 嗜睡 SOMNOLENCE (一般 GENERAL 郁闷 DEPRESSED 活动 ACTIVITY)
日志 Journal of 药用的 中 Medicinal 化学 Chemistry. 卷 Vol. 10, pg. 1172 Pg. 1172, 1967.
老鼠 口服 oral-老鼠 mouse LD50 4400 mg/kg
欧洲 European 专利 Patent 应用 Application. 卷 Vol. #0192191
静脉内大鼠 intravenous-rat LD50 1140 mg/kg
GASTROINTESTINAL: 其他变化 OTHER CHANGES
欧洲 European 日志 Journal of 呼吸的 Respiratory 疾病 Diseases. 卷 Vol. 61(补给 Suppl
口鼠 口服 oral-rat LD50 5050 mg/kg
Toxicology and 已应用 Applied 药理 Pharmacology. 卷 Vol. 18, pg。 185 Pg. 185, 1971.
静脉狗 intravenous-dog LD50 700 mg/kg
Pharmacological and 生化 Biochemical 属性 Properties of 药品 Drug 物质 Substances. 卷 Vol. 2, pg。 479 Pg. 479, 1979.
口头狗 口服 oral-dog LD50 > 1000 mg/kg
Pharmacological and 生化 Biochemical 属性 Properties of 药品 Drug 物质 Substances. 卷 Vol. 2, pg。 479 Pg. 479, 1979.
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| 皮肤毒性 Dermal Toxicity: |
|
未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | | special dietary and nutritional additives |
| 乙酰-半胱氨酸-半胱氨酸使用水平的推荐值 Recommendation for acetyl-laevo-cysteine usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 乙酰-半胱氨酸-半胱氨酸风味剂使用推荐水平最高为 Recommendation for acetyl-laevo-cysteine flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
欧洲食品安全局（efsa EFSA）参考 :
|
食品添加剂科学小组的意见 Opinion of the Scientific Panel on Food Additives, 调味料 Flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in 联系 Contact with Food (afc AFC) on a request from the 佣金 Commission 有关 related to N-Acetyl-L-cysteine for use in 食物 foods for 特定 particular nutritional uses and in 食物 foods for special 医疗 medical purposes
视图 View page or 视图 View pdf
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| Epi系统 EPI System: 视图 View |
| Clinicaltrials.gov ClinicalTrials.gov:search |
| 每日医学 Daily Med:search |
| nlm NLM有害物质数据库 :搜索 Search |
| 化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search |
| 辅助引文 AIDS Citations:搜索 Search |
| 癌症引文 Cancer Citations:搜索 Search |
| 毒理学引文 Toxicology Citations:搜索 Search |
| 致癌力数据库 Carcinogenic Potency Database:搜索 Search |
| 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search |
| 橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search |
| EPA物质注册服务（tsca TSCA） :616-91-1 |
| EPA ACToR:毒理学资料 Toxicology Data |
| EPA物质注册服务（SRS） :注册表 Registry |
| 实验室化学安全摘要 Laboratory Chemical Safety Summary :12035 |
| 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data |
| 德国wgk WGK Germany:2 |
| （2r）-2-乙酰氨基-3-硫烷基丙酸 (2R)-2-acetamido-3-sulfanylpropanoic acid |
| chemidplus Chemidplus:0000616911 |
| 技术 RTECS:适用于CAS＃616-91-1的ha1660000 HA1660000 for cas# 616-91-1 |
参考资料 References:
| | （2r）-2-乙酰氨基-3-硫烷基丙酸 (2R)-2-acetamido-3-sulfanylpropanoic acid |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 616-91-1 |
| pubchem（cid） Pubchem (cid): | 12035 |
| pubchem（sid） Pubchem (sid): | 134978062 |
其他资料 Other Information:
| （iupac） (IUPAC): | 元素的原子量2009 Atomic Weights of the Elements 2009 |
| （iupac） (IUPAC): | 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) |
| 影片 Videos: | 元素周期表 The Periodic Table of Videos |
| RBC : | 本网站使用的原子量 Atomic Weights use for this web site |
| （iupac） (IUPAC): | 元素周期表 Periodic Table of the Elements |
| CHEBI: | 视图 View |
| CHEMBL: | 视图 View |
| 格尔姆代谢组数据库 Golm Metabolome Database: | 搜索 Search |
| KEGG (GenomeNet): | C06809 |
| hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): | HMDB01890 |
| 食物 FooDB: | FDB002281 |
| 出口关税代码 Export Tariff Code: | 2930.90.9190 |
| fda食品添加剂状况清单 FDA Listing of Food Additive Status: | 视图 View |
| 医药线 MedlinePlusSupp: | 视图 View |
| 化学蜘蛛 ChemSpider: | 视图 View |
| 维基百科 Wikipedia: | 视图 View |
| rsc学习化学 RSC Learn Chemistry: | 视图 View |
配方/制剂 Formulations/Preparations:
肠胃外的 parenteral: 用于注射浓缩液 for injection concentrate, 静脉输液 for iv infusion: 200毫克乙酰丙酮（坎伯兰）。 200 mgml acetadote (cumberland).
口服吸入 oral inhalation, 气管内滴注 intratracheal instillation, 和口头的 and oral: 解 solution: 每毫升100毫克（乙酰半胱氨酸）（10％） 100 mg (of acetylcysteine) per ml (10%), 乙酰半胱氨酸钠溶液 acetylcysteine sodium solution, （雅培 (abbott, 美国摄政 american regent, 贝德福德 bedford, dey dey , 梅恩 mayne, 环烷）; 粘液囊 mucomyst（山德士 sandoz）；每毫升（20％）乙酰半胱氨酸钠溶液（雅培 abbott）200毫克（乙酰半胱氨酸） , 美国摄政 american regent, 贝德福德 bedford, dey dey , 梅恩 mayne, 环烷）; 粘液囊 mucomyst（山德士 sandoz）。乙酰半胱氨酸钠
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潜在搅拌机 Potential Blenders and core components note
潜在用途 Potential Uses:
| | 抗氧化剂 antioxidants |
| | 皮肤调理 skin conditioning |
存在（自然 Occurrence (nature, food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| (R)-2- | acetamido-3-mercaptopropanoic acid | | (2R)-2- | acetamido-3-sulfanyl-propanoic acid | | (2R)-2- | acetamido-3-sulfanylpropanoic acid | | L-a- | acetamido-b-mercaptopropionic acid | | L-alpha- | acetamido-beta-mercaptopropionic acid | | laevo-alpha- | acetamido-beta-mercaptopropionic acid | | | 乙酰半胱氨酸 acetilcisteina | | | acetyl cysteine | | N- | acetyl-3-mercaptoalanine | | N- | acetyl-L-(+)-cysteine | | N- | acetyl-L-cysteine | | | acetyl-laevo-cysteine | | N- | acetyl-laevo-cysteine | | (R)-2- | 乙酰氨基 acetylamino-3-mercaptopropanoic acid | | (2R)-2- | 乙酰氨基 acetylamino-3-sulfanylpropanoic acid | | 2-( | 乙酰氨基 acetylamino)-3-mercaptopropionic acid | | (2R)-2-( | 乙酰氨基 acetylamino)-3-sulfanylpropanoic acid | | | acetylcysteine | | | 乙酰半胱氨酸 acetylcysteinum | | | 翻译 airbron | | | 支气管溶血素 broncholysin | | | brunac brunac | | | cysteine, n-（1-羟乙叉）- N-(1-hydroxyethylidene)-, (Z)- | | L- | cysteine, 正乙酰基 N-acetyl- | | | cysteine, 正乙酰基 N-acetyl-, L- | | | 外来的 exomuc | | | Fabrol fabrol | | | fluatox fluatox | | | 氟米西 fluimicil 婴儿 infantil | | | 氟西汀 fluimucetin | | | 氟米西 fluimucil | | | 氟西汀 flumucetin | | | 氟哌威 fluprowit | | | 启发 inspir | | | 纳克 L纳克 NAC | | | 溶酶 lysomucil | | | 巯基 mercapturic acid | | (R)- | 巯基 mercapturic acid | | | 粘膜纤维蛋白 mucofilin | | | 粘液剂 mucolator | | | 解粘液 粘液溶解 mucolyticum | | | 粘液菌 mucolytikum 笔记本 lappe | | | 粘液囊 mucomyst | | | 黏土 mucosil | | | 粘液索尔文 mucosolvin | | | mucret mucret | | | 纳斯卡 NASGC | | | 细语 parvolex | | | 回应 respaire | | | 泰克斯 tixair |
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| 已发布 PubMed:细胞内氧化应激敏感途径参与 类福禄杆菌b白血病细胞中福禄生b诱导的光细胞毒性。 Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells. |
| 已发布 PubMed:异obtusilactone甲使 肝癌hep g2细胞通过ros和chop介导的dr5上调对尾随诱导的细胞凋亡敏感。 Isoobtusilactone A sensitizes human hepatoma Hep G2 cells to TRAIL-induced apoptosis via ROS and CHOP-mediated up-regulation of DR5. |
| 已发布 PubMed:氨基酰基酶1催化生物活性物质环氧化物的脱乙酰化，霉菌毒素衍生的巯基化物； 3 Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-环氧前胞烯作为细胞毒性环氧化物的模型。 4-epoxyprecocenes as models of cytotoxic epoxides. |
| 已发布 PubMed:氧化应激损害hif1α激活 Oxidative stress impairs HIF1α activation: 一种增加脂肪变性肝细胞对低氧应激的脆弱性的新机制。 a novel mechanism for increased vulnerability of steatotic hepatocytes to hypoxic stress. |
| 已发布 PubMed:2-十二烷基环丁酮诱导细胞凋亡的分子机制 Molecular mechanisms of apoptosis induction by 2-dodecylcyclobutanone, 棕榈酸放射分解产物 a radiolytic product of palmitic acid, 在 类淋巴瘤u937细胞中 in human lymphoma U937 cells. |
| 已发布 PubMed:异硫氰酸苄酯（bitc）通过活性氧（ros）以及线粒体依赖性和死亡受体介导的多种信号通路诱导 黑素瘤a375.s2细胞g2 / m期停滞和凋亡。 Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways. |
| 已发布 PubMed:紫锥菊中的橙花酰胺通过jnk途径介导的ho-1表达来预防脂多糖/ d-半乳糖胺诱导的急性肝损伤。 Echinacea alkamides prevent lipopolysaccharide/D-galactosamine-induced acute hepatic injury through JNK pathway-mediated HO-1 expression. |
| 已发布 PubMed: 参皂苷rb1抑制大鼠肝星状细胞中的细胞活化和肝纤维化。 Ginsenoside Rb1 inhibits cell activation and liver fibrosis in rat hepatic stellate cells. |
| 已发布 PubMed: laetiporus Laetiporus 硫脲 sulphureus var。的外多糖微型 miniatus下调lps诱导的no产生 , pge² PGE₂, bv2小胶质细胞中的tnf-α和tnf-α通过抑制nf-κb途径。 and TNF-α in BV2 microglia cells via suppression of the NF-κB pathway. |
| 已发布 PubMed: n-乙酰基-1-半胱氨酸对马尼布 maneb诱导的中国仓鼠v79细胞氧化和凋亡损伤的保护作用 |
| 已发布 PubMed:L-cysteine, 正乙酰基半胱氨酸 N-acetyl-L-cysteine, 谷胱甘肽和谷胱甘肽在青蛙胚胎致畸试验中可以保护非洲爪蟾胚胎免受丙烯酰胺诱导的畸形和死亡。 and glutathione protect Xenopus laevis embryos against acrylamide-induced malformations and mortality in the frog embryo teratogenesis assay. |
| 已发布 PubMed:槲皮素通过减弱尾部悬吊小鼠中泛素连接酶的诱导作用来防止因卸载而导致的废弃肌肉萎缩。 Quercetin Prevents Unloading-Derived Disused Muscle Atrophy by Attenuating the Induction of Ubiquitin Ligases in Tail-Suspension Mice. |
| 已发布 PubMed:表面处理和涂层，以保持鲜切芒果的品质。 Surface treatments and coatings to maintain fresh-cut mango quality in storage. |
| 已发布 PubMed:白藜芦醇 Resveratrol, 饮食中的多酚植物抗毒素 a dietary polyphenolic phytoalexin, 是过氧亚硝酸盐的功能清除剂。 is a functional scavenger of peroxynitrite. |
| 已发布 PubMed:6-脱氢姜二酮通过活性氧介导的dr5的增加使 肝母细胞瘤hep g2细胞对尾随诱导的细胞凋亡敏感。 6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5. |
| 已发布 PubMed:大蒜的蛋白质细胞毒性成分诱导int-407肠细胞凋亡。 Proteinaceous cytotoxic component of Allium sativum induces apoptosis of INT-407 intestinal cells. |
| 已发布 PubMed:代谢组学研究尿液中对乙酰氨基酚和代谢物及其与毒性的关系。 Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. |
| 已发布 PubMed:（-）-epigallocatechin-3-gallate通过与活性氧有关的线粒体途径诱导 肝癌细胞凋亡。 (-)-Epigallocatechin-3-gallate induces apoptosis of human hepatoma cells by mitochondrial pathways related to reactive oxygen species. |
| 已发布 PubMed:运动引起的血浆氧化生成能力的升高增强了脂多糖刺激的时间性炎症反应。 Exercise-induced elevation in plasma oxidative generating capability augments the temporal inflammatory response stimulated by lipopolysaccharide. |
| 已发布 PubMed:巯基酸（n-乙酰基-1-半胱氨酸）-黄曲霉毒素b1加合物的合成，表征及其在大鼠尿液中的酶免疫定量分析。 Synthesis and characterization of mercapturic acid (N-acetyl-L-cysteine)-aflatoxin B1 adduct and its quantitation in rat urine by an enzyme immunoassay. |
| 已发布 PubMed:苯乙基异硫氰酸酯抑制前列腺癌细胞中的stat3活化。 Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells. |
| 已发布 PubMed:提高鲜切苹果的质量 Improving the quality of fresh-cut apples, 梨 pears, 和瓜使用天然添加剂。 and melons using natural additives. |
| 已发布 PubMed:高效液相色谱-二极管阵列检测器与电喷雾电离/质谱联用同时测定当归中的香豆素 The effects of green tea (-)-epigallocatechin-3-gallate on reactive oxygen species in 3T3-L1 preadipocytes and adipocytes depend on the glutathione and 67 kDa laminin receptor pathways. |
| 已发布 PubMed:家禽蛋白质氨基酸营养研究进展。 Advances in protein-amino acid nutrition of poultry. |
| 已发布 PubMed:海藻酸盐可食用涂层中掺入精油以确保鲜切富士苹果的安全性和质量的比较研究。 Comparative study on essential oils incorporated into an alginate-based edible coating to assure the safety and quality of fresh-cut Fuji apples. |
| 已发布 PubMed:高效液相色谱/电喷雾串联质谱法表征模型体系和苹果汁中绿原酸醌与氨基酸衍生物的共价加成产物 Characterization of covalent addition products of chlorogenic acid quinone with amino acid derivatives in model systems and apple juice by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. |
| 已发布 PubMed:hicep鉴定对低剂量亚砷酸盐有响应的基因。 Identification of Genes Responding to Low-Dose Arsenite Using HiCEP. |
| 已发布 PubMed:抗氧化剂对atm缺乏小鼠的癌症预防和橙花运动功能的影响。 Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. |
| 已发布 PubMed:饮食因素对ht-29 结肠直肠癌细胞中（-）-表没食子儿茶素-3-没食子酸酯诱导的前基质金属蛋白酶7产生的影响。 Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells. |
| 已发布 PubMed:硒通过激活jnk通路对镉诱导的llc-pk1细胞凋亡的细胞保护作用。 Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway. |
| 已发布 PubMed:槟榔提取物通过诱导氧化应激抑制t细胞活化和γ干扰素产生。 Areca nut extract suppresses T-cell activation and interferon-gamma production via the induction of oxidative stress. |
| 已发布 PubMed:异obtusilactone a诱导的 肝癌hep g2细胞凋亡是通过增加nadph氧化酶衍生的活性氧（ros）产生和线粒体相关的凋亡机制介导的。 Isoobtusilactone A-induced apoptosis in human hepatoma Hep G2 cells is mediated via increased NADPH oxidase-derived reactive oxygen species (ROS) production and the mitochondria-associated apoptotic mechanisms. |
| 已发布 PubMed:hk-2 肾细胞系中ra曲霉毒素A诱导的dna氧化损伤 Oxidative DNA damage induced by Ochratoxin A in the HK-2 human kidney cell line: 与细胞毒性有关的证据。 evidence of the relationship with cytotoxicity. |
| 已发布 PubMed:n-乙酰半胱氨酸是接受肠外营养的新生仔猪中半胱氨酸高度可用的前体。 N-acetylcysteine is a highly available precursor for cysteine in the neonatal piglet receiving parenteral nutrition. |
| 已发布 PubMed:活性氧在血管内皮细胞中介导剪切应力诱导的液相内吞作用。 Reactive oxygen species mediate shear stress-induced fluid-phase endocytosis in vascular endothelial cells. |
| 已发布 PubMed:活性氧参与3-氨基-1的免疫抑制作用 Involvement of reactive oxygen species in the immunosuppressive effect of 3-amino-1,4-二甲基-5h-吡啶[4 4-dimethyl-5H-pyrido[4,3-b]吲哚（trp-p-1） 3-b]indole (Trp-P-1), 一种食源性致癌杂环胺。 a food-born carcinogenic heterocyclic amine. |
| 已发布 PubMed:三酰基甘油介导的氧化应激抑制大鼠离体肝细胞中一氧化氮的产生。 Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes. |
| 已发布 PubMed:萝卜硫素和萝卜硫烷的n-乙酰半胱氨酸结合物诱导鼠肝癌细胞中醌还原酶的诱导 Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells. |
| 已发布 PubMed:萝卜硫素对 肝癌hepg2细胞中金属硫蛋白表达及凋亡诱导的影响 Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. |
| 已发布 PubMed:（-）-epigallocatechin-3-gallate通过激活ht-29 结肠直肠癌细胞中的jnk1 / 2途径来促进基质金属蛋白酶7的产生。 (-)-Epigallocatechin-3-gallate promotes pro-matrix metalloproteinase-7 production via activation of the JNK1/2 pathway in HT-29 human colorectal cancer cells. |
| 已发布 PubMed:通过调节bcl-2基因和激活c-jun n端激酶在肝癌细胞中激活花色素苷诱导凋亡。 Induction of apoptosis by the Anthocyanidins through regulation of Bcl-2 gene and activation of c-Jun N-terminal kinase cascade in hepatoma cells. |
| 已发布 PubMed:丙烯腈诱导的毒性和离体大鼠结肠细胞的氧化应激。 Acrylonitrile-induced toxicity and oxidative stress in isolated rat colonocytes. |
| 已发布 PubMed:水解曲霉/酿酒酵母/大麦发酵提取物滤液是通过全植物发酵获得的产物的提取物的滤液的水解产物 Hot-water extracts from adzuki beans (Vigna angularis) suppress not only the proliferation of KATO III cells in culture but also benzo(a)pyrene-induced tumorigenesis in mouse forestomatch. |
| 已发布 PubMed: 新型p53杂合tg.ac（v-ha-ras）双转基因小鼠的肿瘤概况，该小鼠经苯并（a）喂 fed处理并饲喂饮食中的n-乙酰基-1-半胱氨酸（nac）。 |
| 已发布 PubMed: 共轭亚油酸介导的Jurkat Jurkat T细胞凋亡涉及活性氧的产生。 |
| 已发布 PubMed:四氢罂粟碱诱导的氧化性dna损伤和橙花胶质瘤细胞死亡。 Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline. |
| 已发布 PubMed:异硫氰酸酯衍生的巯基酸合成。 Synthesis of isothiocyanate-derived mercapturic acids. |
| 已发布 PubMed:乙酯2-乙酰基丁酸乙酯2-乙酰基丁酸乙酯2-乙基-3-酮丁酸乙酯2-乙基-3-氧代丁酸乙酯2-乙基乙酰乙酸乙酯α-乙酰基丁酸乙酯α-乙基乙酰乙酸乙酯2-乙基乙酰乙酸乙酯2-乙基-3 -氧代丁酸乙酯 Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis. The role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis. |
| 已发布 PubMed:氧化应激在och曲霉毒素A介导的近端肾小管细胞毒性中的作用。 The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells. |
| 已发布 PubMed:生物活性化合物对流感 特异性b细胞和t细胞反应的体外作用。 In vitro effect of bioactive compounds on influenza virus specific B- and T-cell responses. |
| 已发布 PubMed:通过图激酶途径和抗氧化剂或亲电子反应元件（are / epre）诱导异种酶。 Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). |
| 已发布 PubMed:丁基化羟基茴香醚诱发毒性的分子机制 Molecular mechanisms of butylated hydroxylanisole-induced toxicity: 通过直接释放细胞色素c诱导凋亡。 induction of apoptosis through direct release of cytochrome c. |
| 已发布 PubMed:棒曲霉素的亲电特性。正乙酰半胱氨酸和谷胱甘肽加合物。 Electrophilic properties of patulin. N-acetylcysteine and glutathione adducts. |
| 已发布 PubMed:细胞内锌螯合诱导的细胞凋亡与大鼠肝细胞中减少的谷胱甘肽水平降低有关。 Apoptosis induced by chelation of intracellular zinc is associated with depletion of cellular reduced glutathione level in rat hepatocytes. |
| 已发布 PubMed:半胱氨酸和正乙酰基半胱氨酸对4-羟基-2的影响 Effects of L-cysteine and N-acetyl-L-cysteine on 4-hydroxy-2, 5-二甲基-3（2h）-呋喃酮（呋喃醇） 5-dimethyl-3(2H)-furanone (furaneol), 5-（羟甲基）糠醛 5-(hydroxymethyl)furfural, 在含有鼠李糖或葡萄糖和精氨酸缓冲溶液中形成5-甲基糠醛并褐变。 and 5-methylfurfural formation and browning in buffer solutions containing either rhamnose or glucose and arginine. |
| 已发布 PubMed:槟榔碱对 口腔粘膜成纤维细胞的细胞毒性与细胞硫醇和酯酶活性有关。 Arecoline cytotoxicity on human oral mucosal fibroblasts related to cellular thiol and esterase activities. |
| 已发布 PubMed:过氧化氢和羟基自由基在化学诱导hl-60细胞凋亡中的作用 Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells. |
| 已发布 PubMed:丁基化羟基茴香醚及其代谢物叔丁基对苯二酚可差异调节促分裂原活化的蛋白激酶。氧化应激在酚类抗氧化剂激活丝裂原活化蛋白激酶中的作用。 Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants. |
| 已发布 PubMed:含硫氨基酸对罐装肝肠中烧焦异味的抑制作用。 Inhibitory effect of sulfur-containing amino acids on burnt off-flavours in canned liver sausages. |
| 已发布 PubMed:姜黄素 Curcumin, 抗氧化剂和抗肿瘤促进剂 an antioxidant and anti-tumor promoter, 诱导 白血病细胞凋亡。 induces apoptosis in human leukemia cells. |
| 已发布 PubMed:姜黄素对大鼠肝脏细胞色素p450和谷胱甘肽S-转移酶活性的影响 Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. |
| 已发布 PubMed:谷胱甘肽氧化还原循环在tnf-α介导的内皮细胞功能障碍中的作用 Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction. |
| 已发布 PubMed:邻苯二甲醛衍生化后，通过毛细管电泳分离正乙酰半胱氨酸对映体。 Separation of enantiomers of N-acetylcysteine by capillary electrophoresis after derivatization by o-phthaldialdehyde. |
| 已发布 PubMed:半胱氨酸生物利用度和来源决定商业肠内产品的蛋白质质量 Bioavailable level and source of cysteine determine protein quality of a commercial enteral product: 喂食新鲜制备或贮存期超过保质期的肠溶产品的大鼠，其色氨酸充足但半胱氨酸不足。 adequacy of tryptophan but deficiency of cysteine for rats fed an enteral product prepared fresh or stored beyond shelf life. |
| 已发布 PubMed:高效液相色谱分离度 High-performance liquid chromatographic resolution of (R, s）-α-烷基-α-氨基酸为非对映异构体衍生物。 S)-α-alkyl-α-amino acids as diastereomeric derivatives. |
| 已发布 PubMed:含sh的氨基酸可防止新鲜和脱水马铃薯褐变。 Browning prevention in fresh and dehydrated potatoes by SH-containing amino acids. |
| 已发布 PubMed:通过邻苯二甲醛和正酰化半胱氨酸衍生化实现氨基酸自动对映体分离。 Automated enantioseparation of amino acids by derivatization with o-phthaldialdehyde and n-acylated cysteines. |
| 已发布 PubMed:异构含硫氨基酸在小鼠中的利用和安全性。 The utilization and safety of isomeric sulfur-containing amino acids in mice. |
| 已发布 PubMed:硫醇使黄曲霉毒素b1致突变性失活。 Inactivation of aflatoxin B1 mutagenicity by thiols. |
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（甲硫基）甲基酯（（甲硫基）甲基）己酸酯甲硫基甲基己酸酯（甲硫基甲基）己酸酯（甲硫基）甲基己酸酯甲硫基甲基己酸酯（甲硫基）甲基己酸酯（（甲硫基）甲基）己酸酯（甲硫基）甲基己酸酯甲硫基甲基己酸酯（甲硫基甲基） the n-acetyl derivative of cysteine. it is used as a mucolytic agent to reduce the viscosity of mucous secretions. it has also been shown to have antiviral effects in patients with hiv due to inhibition of viral stimulation by reactive oxygen intermediates. Effective inhibitor of enzymic browning in foods [DFC]
n-乙酰基-1-半胱氨酸是一种药物和营养补品，主要用作粘液溶解剂并用于扑热息痛（对乙酰氨基酚）过量的治疗。其他用途包括在一定条件下补充硫酸盐 N-Acetyl-L-cysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose. Other uses include sulfate repletion in conditions, 如自闭症 such as autism, 半胱氨酸和相关的硫氨基酸可能耗尽的地方。 n-乙酰基-1-半胱氨酸是体内抗氧化剂谷胱甘肽形成的前体。硫醇基团具有抗氧化作用，能够减少自由基。 [维基百科] where cysteine and related sulfur amino acids may be depleted. N-Acetyl-L-cysteine is a precursor in the formation of the antioxidant glutathione in the body. The thiol group confers antioxidant effects and is able to reduce free radicals. [Wikipedia]
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3D/INCHI