tosylamide
苯磺酰胺 benzenesulfonamide, 4-甲基 4-methyl-

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    t0281对甲苯磺酰胺> 98.0%(hplc)(n) T0281 p-Toluenesulfonamide >98.0%(HPLC)(N)
CAS号 CAS Number: 70-55-3Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:200-741-1
FDA UNII:I8266RI90M
nikkaji网站 Nikkaji Web:J4.878J
贝尔斯坦数 Beilstein Number:0472689
MDL :mfcd00011692 MFCD00011692
XlogP3-AA:0.80(est) 0.80 (est)
分子量 Molecular Weight:171.21913000
式 Formula:c7 h9 n o2 s C7 H9 N O2 S
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:plasticizers
 
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谷歌学术 Google Scholar: with word "volatile"搜索 Search
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fda mainterm(iaufc) FDA Mainterm (IAUFC):70-55-3 ; TOLUENESULFONAMIDE, p- P-

 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 138.50 °C. @ 760.00 mm 汞 Hg
logp(o / w) logP (o/w): 0.820
溶于 Soluble in:
 水 water, 3160 mg / l @ 25°C(实验) 3160 mg/L @ 25 °C (exp)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: 增塑剂 plasticisers
 
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BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
对甲苯磺酰胺 p-Toluenesulfonamide
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仅供实验/研究使用。 For experimental / research use only.
对甲苯磺酰胺 p-Toluenesulfonamide
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对甲苯磺酰胺 p-Toluenesulfonamide
西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich
仅供实验/研究使用。 For experimental / research use only.
对甲苯磺酰胺 p-Toluenesulfonamide ReagentPlus®, ≥99%
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
对甲苯磺酰胺> 98.0%(hplc)(n) p-Toluenesulfonamide >98.0%(HPLC)(N)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
口鸟 口服 oral-bird - 野生 wild LD50 75 mg/kg
Toxicology and 已应用 Applied 药理 Pharmacology. 卷 Vol. 21, pg。 315 Pg. 315, 1972.

腹腔内小鼠 intra腹膜的 peritoneal-老鼠 mouse LD50 250 mg/kg
国民 National 技术 Technical Information 服务 Service. 卷 Vol. AD691-490

皮肤毒性 Dermal Toxicity:
皮下几内亚 subcutaneous-guinea 猪 pig ldlo LDLo 2000 mg/kg
行为的 BEHAVIORAL: 嗜睡(一般抑郁活动) SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) 行为的 BEHAVIORAL: 激动 EXCITEMENT 行为的 BEHAVIORAL: 肌肉 MUSCLE WEAKNESS
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 14, pg。 259 Pg. 259, 1920.

吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: plasticizers
推荐的甲苯磺酰胺用量不超过 Recommendation for tosylamide usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐的甲苯磺酰胺风味剂使用水平最高为 Recommendation for tosylamide flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
尼什国际化学品安全卡 NIOSH International Chemical Safety Cards:search
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环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
EPA物质注册服务(tsca TSCA) :70-55-3
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :6269
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
4-甲基苯磺酰胺 4-methylbenzenesulfonamide
chemidplus Chemidplus:0000070553
技术 RTECS:70-55-3
 
参考资料 References:
 4-甲基苯磺酰胺 4-methylbenzenesulfonamide
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:70-55-3
pubchem(cid) Pubchem (cid):6269
pubchem(sid) Pubchem (sid):134971979
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
用于食品接触物质的fda间接添加剂 FDA Indirect Additives used in Food Contact Substances:视图 View
CHEBI:视图 View
CHEMBL:视图 View
KEGG (GenomeNet):C14412
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
出口关税代码 Export Tariff Code:2935.00.9500
雾度图 Haz-Map:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, 餐饮 food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 苯磺酰胺 benzenesulfonamide, 4-甲基 4-methyl-
4-methyl苯磺酰胺 benzenesulfonamide
p-methyl苯磺酰胺 benzenesulfonamide
para-toluene sulfonamide
 toluene-4-sulfonamide
 toluene-p-sulphonamide
p-toluenesulfamide
4-toluenesulfanamide
4-toluenesulfonamide
p-toluenesulfonamide
para-toluenesulfonamide
4-toluenesulfonic acid, amide
p-toluene磺酰基 sulfonylamide
 tolylsulfonamide
p-tolylsulfonamide
 tosyl amide
p-tosylamide
 

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PubMed:一个小男孩对甲苯磺酰胺/甲醛树脂过敏 Tosylamide/formaldehyde resin allergy in a young boy: 用于防止指甲咬伤的苦指甲油暴露。 exposure from bitter nail varnish used against nail biting.
PubMed:甲苯磺酰胺甲醛树脂。 Tosylamide formaldehyde resin.
PubMed:甲苯磺酰胺/甲醛树脂过敏-特应性学步者的考虑因素。 Tosylamide/formaldehyde resin allergy--a consideration in the atopic toddler.
PubMed:dabco介导的三组分偶联反应和正甲苯胺和tms取代的丙酸酯的环化反应。 Three-component coupling reaction and cyclization of N-tosylimines and TMS-substituted propiolate mediated by DABCO.
PubMed:指甲油中甲苯磺酰胺甲醛树脂引起的过敏性接触性皮炎 Allergic contact dermatitis caused by tosylamide formaldehyde resin in nail varnish: 尚未消失的旧变应原。 an old allergen that has not disappeared.
PubMed:眼睑皮炎的病因 The aetiology of eyelid dermatitis: 十年回顾性分析。 a 10-year retrospective analysis.
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PubMed:在瓦克型条件下,钯(ii)催化内氨基甲酸酯的分子内氨基羰基化作用。 Palladium(II)-Catalyzed Intramolecular Aminocarbonylation of endo-Carbamates under Wacker-Type Conditions.
PubMed:从凋亡性肿瘤细胞中纯化24 kd蛋白酶,激活dna片段。 Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation.
PubMed:野猪附睾附睾胚芽中一种新的类似于丙烯醛的酶的纯化和鉴定。 Purification and characterization of a novel acrosin-like enzyme from boar cauda epididymal sperm.
PubMed:使用电喷雾质谱法对镰状细胞血红蛋白进行直接肽图分析。 Direct peptide mapping of sickle-cell hemoglobin using electrospray mass spectrometry.
PubMed:埃及伊蚊胰蛋白酶调节渗透因子(tmof)及其类似物的质谱分析和表征。 Mass spectrometry and characterization of Aedes aegypti trypsin modulating oostatic factor (TMOF) and its analogs.
PubMed:抑制 血浆α1-抗胰蛋白酶对中性粒细胞超氧化物的产生。 Inhibition of neutrophil superoxide production by human plasma alpha 1-antitrypsin.
PubMed:粒细胞巨噬细胞集落刺激因子是 类嗜中性粒细胞产生的血小板激活因子和超氧阴离子的刺激物。 Granulocyte-macrophage colony-stimulating factor is a stimulant of platelet-activating factor and superoxide anion generation by human neutrophils.
PubMed:蛋白酶抑制剂减少艾美耳球虫(球虫)子孢子的细胞进入 Reduction in cell entry of Eimeria tenella (Coccidia) sporozoites by protease inhibitors, 和与完整子孢子和裂殖子有关的蛋白水解活性的部分表征。 and partial characterization of proteolytic activity associated with intact sporozoites and merozoites.
PubMed:用于诊断和治疗的放射性金属大环螯合物。 Macrocyclic chelates of radiometals for diagnosis and therapy.
PubMed:二甲胺的测定 The measurement of dimethylamine, 三甲胺 trimethylamine, 毛细管气相色谱-质谱法测定三甲胺正氧化物 and trimethylamine N-oxide using capillary gas chromatography-mass spectrometry.
PubMed:定点荧光试剂鉴定 胎盘谷胱甘肽转移酶中高反应性巯基。 Identification of a highly reactive sulphydryl group in human placental glutathione transferase by a site-directed fluorescent reagent.
PubMed:血清蛋白酶抑制剂废除新城疫 通过重组肿瘤坏死因子α和β增强细胞溶解作用。 Serum protease inhibitor abrogation of Newcastle disease virus enhancement of cytolysis by recombinant tumor necrosis factors alpha and beta.
PubMed:用于放射治疗的金属的稳定双功能螯合物。 Stable bifunctional chelates of metals used in radiotherapy.
PubMed: nk NK细胞介导的细胞毒性中的细胞表面相关蛋白酶 : 酶表达的增强是α-干扰素激活所特有的。 enhancement of enzyme expression is unique to activation with interferon-alpha.
PubMed:阴道毛滴虫表面蛋白酶活性对于寄生虫粘附到上皮细胞是必需的。 Trichomonas vaginalis surface proteinase activity is necessary for parasite adherence to epithelial cells.
PubMed:非洲爪蟾皮肤arg-xaa-val-arg-gly-内切蛋白酶。在肽激素前体的共有序列的单个精氨酸后裂解的高特异性蛋白酶。 Xenopus laevis skin Arg-Xaa-Val-Arg-Gly-endoprotease. A highly specific protease cleaving after a single arginine of a consensus sequence of peptide hormone precursors.
PubMed:胰凝乳蛋白酶样蛋白酶的抑制剂抑制了海胆胚芽顶体反应过程中ca2 +通道的激活。 Activation of Ca2+ channels during the acrosome reaction of sea urchin sperm is inhibited by inhibitors of chymotrypsin-like proteases.
PubMed: 苏云金芽孢杆菌库尔斯塔克毒素对毛状毛滴虫(棒状毛圆 Trichostrongylus colubriformis)( )卵和幼虫致死性的影响因素。
PubMed: 多形核明串球菌从唾液包被的羟基磷灰石上分离口腔细菌。 Detachment of oral bacteria from saliva-coated hydroxyapatite by human polymorphonuclear leukocytes.
PubMed:贾第鞭毛虫 Giardia lamblia: 营养体中蛋白酶活性的特征。 characterization of proteinase activity in trophozoites.
PubMed:从密 体中分离出胰凝乳蛋白酶样酶。 Isolation of a chymotrypsinlike enzyme from Treponema denticola.
PubMed: 棕榈酰肉碱逆转12-o-十四烷酰佛波醇 phorbol-13-乙酸酯诱导的难治性状态,导致小鼠表皮中tpa引起的鸟氨酸脱羧酶诱导。
PubMed:蛋白酶抑制剂和底物对2的影响 Influence of proteinase inhibitors and substrates on 2,3,7,大鼠肝ah受体的8-四氯二苯并-对二恶英(tcdd)结合能力。 8-tetrachlorodibenzo-p-dioxin (TCDD)-binding capacity of the rat hepatic Ah receptor.
PubMed:气候变化可以解释法国佩里戈尔黑松露批发市场的年度波动,但不能解释过去48年黑松露产量的下降。 Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent.
PubMed:丝氨酸蛋白酶参与自然杀伤细胞裂解反应后期的证据。 Evidence for involvement of serine proteases in the late stages of the natural killer cell lytic reaction.
PubMed:在各种刺激下 类嗜中性粒细胞激活机制中细胞结合蛋白酶的需求。 Requirement for cell-bound proteases in the mechanism of human neutrophil activation with various stimuli.
PubMed:金鱼脑细胞外液蛋白 Extracellular fluid proteins of goldfish brain: 蛋白酶和酯酶存在的证据。 evidence for the presence of proteases and esterases.
PubMed:黄素化大鼠 中膜蛋白酶的电泳分析。 Electrophoretic analysis of membrane proteases in the luteinized rat ovary.
PubMed:密 体密 体产生的能够水解合成胰蛋白酶底物的酶的纯化和表征。 Purification and characterization of an enzyme produced by Treponema denticola capable of hydrolyzing synthetic trypsin substrates.
PubMed:美洲红皮皮提取物美国红皮皮提取物美国美洲红皮皮提取物南非红皮。萨摩皮提取物萨摩皮提取物 Reducing conditions induce a total degradation of the major zymogen granule membrane protein in both its membranous and its soluble form. Immunochemical quantitation of the two forms.
PubMed:凝集素结合位点与大鼠腹水肝细胞粘附有关。 Lectin binding sites related with rat ascites hepatoma cell adhesion.
PubMed:棒状毛圆 Trichostrongylus colubriformis: 苏云金芽孢杆菌结晶毒素引起的卵致死率。 egg lethality due to Bacillus thuringiensis crystal toxin.
PubMed:通过用蛋白酶和蛋白激酶亲和标记对刘易斯肺癌细胞进行预移植治疗,可降低潜在的转移潜力。 Decrease of metastatogenic potential by pregraft treatment of Lewis lung carcinoma cells with proteinase and protein kinase affinity labels.
PubMed:结节细菌良性和强 株产生的某些蛋白酶同工酶的特征。 Characterization of certain proteinase isoenzymes produced by benign and virulent strains of Bacteroides nodosus.
PubMed:白介素-1的特性,可作为 类嗜中性粒细胞的完全促分泌素。 Properties of interleukin-1 as a complete secretagogue for human neutrophils.
PubMed:菠菜茧/愈合组织微粒体中的一种膜结合蛋白酶。 A membrane-bound protease in microsomes of spinach callus.
PubMed:狗精浆中精氨酸酯酶的酶学表征。 Enzymatic characterization of arginine esterase from dog seminal plasma.
PubMed:对 类外周血nk细胞裂解中对烷基化酮敏感的细胞表面大分子的参与。 Involvement of cell surface macromolecules sensitive to alkylating ketones in lysis by human peripheral blood NK cells.
PubMed: 单核细胞白血病细胞系thp-1中具有杀肿瘤作用的单因子的分离和初步鉴定。 Isolation and initial characterization of tumoricidal monokine(s) from the human monocytic leukemia cell line THP-1.
PubMed:蛋白酶抑制自然杀手(nk)和抗体依赖性细胞介导的细胞毒性(adcc)活性。 Protease inhibition of natural killer (NK) and antibody-dependent cell-mediated cytoxicity (ADCC) activities.
PubMed:佛波醇酯诱导的鼠红细胞白血病细胞粘附 Phorbol ester-induced adhesion of murine erythroleukemia cells: 细胞蛋白酶可能参与其中。 possible involvement of cellular proteases.
PubMed:聚丙烯酰胺凝胶电泳鉴定肿瘤细胞膜丝氨酸蛋白酶。 Characterization of tumor cell membrane serine proteases by polyacrylamide gel electrophoresis.
PubMed: 抑制蛋白酶抑制剂抑制12-o-十四烷酰佛波醇 phorbol-13-乙酸盐诱导的表皮转谷氨酰胺酶活性。
PubMed:疟原虫 Plasmodium knowlesi: 蛋白酶抑制剂存在下裂殖子入侵恒河猴红细胞的研究 studies on invasion of rhesus erythrocytes by merozoites in the presence of protease inhibitors.
PubMed:蛋白酶和蛋白酶抑制剂对牛甲状腺腺苷酸环化酶活性的影响 Effects of proteolytic enzymes and protease inhibitors on bovine thyroid adenylate cyclase activity.
PubMed:大鼠垂体前叶分泌颗粒中促肾上腺皮质激素转化活性的特征。 Characterization of proopiocortin converting activity in rat anterior pituitary secretory granules.
PubMed:蛋白酶抑制剂对角叉菜胶诱导的大鼠炎症的抗炎作用。 Anti-inflammatory effect of proteinase inhibitors on carrageenin-induced inflammation in rats.
PubMed:在蛋白水解抑制剂存在下体外生产皮质类固醇粘合剂ib。 In vitro production of corticosteroid binder IB in the presence of proteolytic inhibitors.
PubMed:豆蔻酸佛波酯的药效 Effect of phorbol myristate acetate, 肿瘤促进剂 a tumor-promoting agent, 对小鼠足垫中分枝杆菌Lepraemurium的生长。 on the growth of Mycobacterium lepraemurium in the mouse footpad.
PubMed:车前子壳(车前子卵)的凝胶形成多糖。 The formylpeptide chemotactic receptor on rabbit peritoneal neutrophils: -1-甲苯磺酰胺-2-苯基乙基氯甲基酮(tpck)改变受体亲和力和数量。 change of receptor affinity and number by L-1-tosylamide-2-phenylethyl chloromethyl ketone (TPCK).
PubMed:增加 公司 Increased 不稳定 lability of 磷酸三糖 triosephosphate 异构酶 isomerase in 早衰 progeria and 我们 Werner's 综合症 syndrome 成纤维细胞 fibroblasts.
PubMed:具有抗炎活性的蛋白酶抑制剂对明胶酶的作用 Effect of proteinase inhibitors having anti-inflammatory activity on gelatinase, 从大鼠多形核明串球菌中分离出的弹性蛋白酶和组织蛋白酶g。 elastase and cathepsin G isolated from rat polymorphonuclear leukocytes.
PubMed:中性粒细胞趋化性的回归线分析。 Regression line analysis of neutrophil chemotaxis.
PubMed: 北极鱼毛鳞鱼(mallotus villosus)分离的两种胰蛋白酶类型同工酶的特征。
PubMed:[酶 [Thermitase, 欧嗜热升麻的热稳定丝氨酸蛋白酶 a thermostable serine protease of Thermoactinomyces vulgaris: 活性中心与酶sh-基的相互作用] interaction of the active center and the SH-group of the enzyme].
PubMed:细胞膜结合的丝氨酸蛋白酶在肿瘤诱导的靶细胞溶解中的作用 Role of tumor cell membrane-bound serine proteases in tumor-induced target cytolysis.
PubMed: 12-邻-十四烷酰佛波醇-13-乙酸盐诱导 恶性t-淋巴细胞生成细胞系molt-3和Jurkat jurkat : 生化 biochemical, 物理 physical, 和形态表征。 and morphological characterization.
PubMed:-1-甲苯磺酰胺-2-苯基乙基氯甲基酮对豚鼠吞噬细胞氧化代谢的两倍效应。 A two-fold effect of L-1-tosylamide-2-phenylethyl chloromethyl ketone on the oxidative metabolism of guinea pig phagocytes.
PubMed:蛋白酶抑制剂抑制角叉菜胶诱导的大鼠炎症中肉芽组织的形成。 Proteinase inhibitors suppress the formation of granulation tissue in the carrageenin-induced inflammation in rats.
PubMed:兔多形核明串球菌溶酶体中性蛋白酶的一些特性 Some properties of neutral proteinases from lysosomes of rabbit polymorphonuclear leucocytes.
PubMed:1-甲苯磺酰胺-2-苯基乙基氯甲基酮对豚鼠吞噬细胞呼吸代谢的双重作用。 A dual effect of L-1-tosylamide-2-phenylethyl chloromethyl ketone on the respiratory metabolism of guinea pig phagocytes.
PubMed:酿酒酵母天冬酰胺酶ii Asparaginase II of Saccharomyces cerevisiae: 过渡到固定相期间失活。 inactivation during the transition to stationary phase.
PubMed:2型腺 蛋白酶。亚细胞定位。 Protease of adenovirus type 2. Subcellular localization.
PubMed:翻译控制7结合的证据 Evidence for translational control of the binding of 7, 培养的鼠表皮细胞中dna的12-二甲基苯并[a]蒽。 12-dimethylbenz[a]anthracene to DNA of murine epidermal cell in culture.
PubMed: 野猪的α-酪蛋白。公猪prorososin转化为顶体蛋白 acrosin产生的初始活性酶的纯化和表征。
PubMed:离子和细胞外蛋白在明串球菌运动和膜起皱中的作用 Role of ions and extracellular protein in leukocyte motility and membrane ruffling.
PubMed: 血单核细胞的表面相关酶降解血清淀粉样蛋白a蛋白。 Degradation of serum amyloid A protein by surface-associated enzymes of human blood monocytes.
PubMed:蛋白酶抑制剂抑制肾上腺和性类固醇激素结合。 Inhibition by protease inhibitors of binding of adrenal and sex steroid hormones.
PubMed:[卢利伯林的分解 [Breakdown of luliberin, 生长抑素和p物质对下丘脑内肽酶的作用] somatostatin and substance P as an effect of hypothalamic endopeptidases].
PubMed: 明串球菌迁移抑制因子(lif)iii。关于这种淋巴因子的丝氨酸蛋白酶性质及其对精氨酸酰胺的偏好的进一步研究。 Human leukocyte migration inhibitory factor (LIF) III. Further investigations on the serine protease nature of this lymphokine and its preference for arginine amides.
PubMed:猿猴 40感染和转化的细胞的t抗原的单体分子量。 Monomer molecular weight of T antigen from simian virus 40-infected and transformed cells.
PubMed:生长前激素 Pregrowth hormone: 信使核糖核酸 RNA的体外翻译产物,编码生长激素。
PubMed: 血浆α-球蛋白抑制剂和合成酯酶抑制剂对 嗜中性粒细胞多形核明串球菌迁移的调节作用。 Modulation of human neutrophil polymorphonuclear leucocyte migration by human plasma alpha-globulin inhibitors and synthetic esterase inhibitors.
PubMed:α-胰凝乳蛋白酶从分离的大鼠肥大细胞中释放组胺的机理 Mechanism of histamine release by alpha-chymotrypsin from isolated rat mast cells.
PubMed:嗜假单胞菌丝氨酸蛋白酶的纯化和性质。 Purification and properties of a serine protease from Pseudomonas matophilia.
 
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