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类别 Category:cosmetic ingredient for skin conditioning
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 熔点 Melting Point: | 212.50 °C. @ 760.00 mm 汞 Hg
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| 溶于 Soluble in: |
| | 水 water, 3.00e + 05 mg / l @ 20°C（实验） 3.00E+05 mg/L @ 20 °C (exp) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
| 首选sds SDS : 视图 View |
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | cosmetic ingredient for skin conditioning |
| 推荐使用肌氨酸水平 Recommendation for sarcosine usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 推荐肌氨酸盐使用水平最高为 Recommendation for sarcosine flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
| | 2-（甲氨基）乙酸 2-(methylamino)acetic acid |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 107-97-1 |
| pubchem（cid） Pubchem (cid): | 1088 |
| pubchem（sid） Pubchem (sid): | 134972744 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | acetic acid, （甲氨基）- (methylamino)- | | | 甘氨酸 glycine, 正甲基 正甲基 n- N-methyl- | | ( | 甲氨基 methyl氨基 amino)acetic acid | | 2-( | 甲氨基 methyl氨基 amino)acetic acid | | ( | 甲氨基 methyl氨基 amino)种族的 ethanoic acid | | n- N- | 甲氨基 methyl氨基 aminoacetic acid | | | methyl甘氨酸 glycine | | n- N- | methyl甘氨酸 glycine | | | sarcosin | | | 肌氨酸 sarcosinic acid |
文章 Articles:
| 已发布 PubMed:大鼠视网膜中甘氨酸释放的一些操作特征 Some Operational Characteristics of Glycine Release in Rat Retina: 在缺血状态下逆向模式操作1型甘氨酸转运蛋白（glyt-1）的作用。 The Role of Reverse Mode Operation of Glycine Transporter Type-1 (GlyT-1) in Ischemic Conditions. |
| 已发布 PubMed:鼠小肠肠内分泌L细胞检测蛋白ept的信号通路 Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells. |
| 已发布 PubMed:母体胆碱状态 Maternal Choline Status, 但不是胎儿基因型 but Not Fetal Genotype, 影响脐带血浆胆碱代谢产物浓度。 Influences Cord Plasma Choline Metabolite Concentrations. |
| 已发布 PubMed:肌酸在生理条件下通过形成正-（4-甲基-5-氧代-1-咪唑啉-2-基）肌氨酸（mg-hcr）清除甲基乙二醛。 Creatine is a scavenger for methylglyoxal under physiological conditions via formation of N-(4-methyl-5-oxo-1-imidazolin-2-yl)sarcosine (MG-HCr). |
| 已发布 PubMed:凹纹牵牛花中可能存在的草甘膦耐受机制。 Possible glyphosate tolerance mechanism in pitted morningglory (Ipomoea lacunosa L.). |
| 已发布 PubMed:食用最低程度加工的麦麸或小麦糊粉后的餐后血浆甜菜碱和其他甲基供体相关的反应 Postprandial plasma betaine and other methyl donor-related responses after consumption of minimally processed wheat bran or wheat aleurone, 或将小麦糊粉掺入面包中。 or wheat aleurone incorporated into bread. |
| 已发布 PubMed:甜菜碱对身体机能和身体成分的影响 Effects of betaine on performance and body composition: 回顾最近的发现和潜在机制。 a review of recent findings and potential mechanisms. |
| 已发布 PubMed:聚胺引发的肌氨酸正硫代羧酸酐向新型双亲水性聚乙二醇-b-聚肌氨酸二嵌段共聚物的聚合。 PEG-amine-initiated polymerization of sarcosine N-thiocarboxyanhydrides toward novel double-hydrophilic PEG-b-polysarcosine diblock copolymers. |
| 已发布 PubMed:1-肌氨酸-血管紧张素II输注对食物摄入的影响 1-Sarcosine-angiotensin II infusion effects on food intake, 减肥 weight loss, 能量消耗 energy expenditure, 和骨骼肌ucp3基因在大鼠模型中的表达。 and skeletal muscle UCP3 gene expression in a rat model. |
| 已发布 PubMed: 在可行的实时pcr中使用月桂酰肌氨酸钠（鲨糖基 sarkosyl）进行大肠杆菌计数。 |
| 已发布 PubMed:北极中生 冷驯化的代谢组学分析。菌株n33。 Metabolomic analysis of cold acclimation of Arctic Mesorhizobium sp. strain N33. |
| 已发布 PubMed:使用肌氨酸比较研究 Comparative study of the use of sarcosine, 脯氨酸和甘氨酸在成熟橄榄加工中作为丙烯酰胺抑制剂。 proline and glycine as acrylamide inhibitors in ripe olive processing. |
| 已发布 PubMed:就水分活度而言，渗透压对核糖核酸酶a热稳定性的影响的热力学分析。 Thermodynamic analysis of osmolyte effect on thermal stability of ribonuclease A in terms of water activity. |
| 已发布 PubMed:嗜酸乳杆菌la5和乳酸双歧杆菌bb12诱导小鼠尿液和粪便中1h-nmr光谱揭示的不同的年龄相关代谢谱。 Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. |
| 已发布 PubMed:碳水化合物对β-半乳糖苷酶的onpg转化活性的影响 Effects of carbohydrates on the oNPG converting activity of β-galactosidases. |
| 已发布 PubMed:dna甲基化电位 DNA methylation potential: 非洲农村妇女的膳食摄入量和一碳代谢产物和辅助因子的血药浓度。 dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women. |
| 已发布 PubMed:茶黄素 Theaflavins, 二聚儿茶素 dimeric catechins, 通过下调amp激活的蛋白激酶介导的肽转运蛋白pept1来抑制跨caco-2细胞单层的肽转运。 inhibit peptide transport across Caco-2 cell monolayers via down-regulation of AMP-activated protein kinase-mediated peptide transporter PEPT1. |
| 已发布 PubMed:塞舌尔儿童发育营养研究中的5岁儿童的胆碱状态和橙花发育结局。 Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study. |
| 已发布 PubMed:irw的运输 Transport of IRW, 卵转铁蛋白衍生的降压肽 an ovotransferrin-derived antihypertensive peptide, 在 肠上皮caco-2细胞中 in human intestinal epithelial Caco-2 cells. |
| 已发布 PubMed: 灰（fraxinus spp spp。）外皮和韧皮部的营养特性及其与对翡翠灰bore的抵抗力的关系。 |
| 已发布 PubMed:唐氏综合症和代谢模拟中使用数学模型的血液甲基化生物标志物。 Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model. |
| 已发布 PubMed:新的稳定的生长素释放肽类似物的表征，具有延长的致癌力。 Characterization of new stable ghrelin analogs with prolonged orexigenic potency. |
| 已发布 PubMed:洋地黄中草甘膦的抗性机制库。 Pool of resistance mechanisms to glyphosate in Digitaria insularis. |
| 已发布 PubMed:荧光相关光谱法观察到低于水/ 2-丁氧基乙醇混合物的较低临界溶液温度时异常分子扩散行为。 Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients. |
| 已发布 PubMed:n的耐受性和安全性评估 Tolerance and safety evaluation of N,正二甲基甘氨酸 N-dimethylglycine, 天然存在的有机化合物 a naturally occurring organic compound, 作为肉鸡日粮中的饲料添加剂。 as a feed additive in broiler diets. |
| 已发布 PubMed:大肠近端小肠切除术后肽的吸收 Peptide absorption after massive proximal small bowel resection: 回肠适应的机制。 mechanisms of ileal adaptation. |
| 已发布 PubMed:通过调节转甲基化动力学和dna甲基化，hepg2细胞中甘氨酸-n甲基转移酶的表达与甲基稳态有关。 Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation. |
| 已发布 PubMed:gnmt表达增加肝叶酸含量和叶酸依赖性蛋氨酸合酶介导的高半胱氨酸再甲基化。 GNMT expression increases hepatic folate contents and folate-dependent methionine synthase-mediated homocysteine remethylation. |
| 已发布 PubMed: （r）斯特龙 -strombine对干贝的味道贡献。 |
| 已发布 PubMed: oseltamivir（达菲 tamiflu）是肽转运蛋白1的底物。 |
| 已发布 PubMed:通透性 Permeabilization of baker's 酵母 yeast with 正月桂基 n- N-lauroyl sarcosine. |
| 已发布 PubMed:浮游和无柄培养中大肠杆菌o157外膜蛋白的表达和推定作用 Expression and putative roles in attachment of outer membrane proteins of Escherichia coli O157 from planktonic and sessile culture. |
| 已发布 PubMed:甜菜碱-高半胱氨酸-s-甲基转移酶-2是s-甲基甲硫氨酸-高半胱氨酸-甲基转移酶。 Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. |
| 已发布 PubMed:dna诱导α-突触核蛋白折叠 DNA induces folding in alpha-synuclein: 了解渗透压分子伴侣性质的机理。 understanding the mechanism using chaperone property of osmolytes. |
| 已发布 PubMed:线粒体疾病的治疗。 Treatment for mitochondrial disorders. |
| 已发布 PubMed:通过使用固有色氨酸荧光和定点诱变来分析甜菜碱-高半胱氨酸-s-甲基转移酶的催化机理。 Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. |
| 已发布 PubMed:唐氏综合症患儿的同型半胱氨酸代谢 Homocysteine metabolism in children with Down syndrome: 体外调制。 in vitro modulation. |
| 已发布 PubMed:胆碱替代 酸治疗短肠综合征。 Bile acid replacement therapy with cholylsarcosine for short-bowel syndrome. |
| 已发布 PubMed:胰岛淀粉样多肽对大鼠下颌器官橙花元和饮酒行为的影响。 Actions of amylin on subfornical organ neurons and on drinking behavior in rats. |
| 已发布 PubMed:评论 Comment: N,正二甲基甘氨酸和左旋肉碱作为运动员的性能增强剂。 N-dimethylglycine and L-carnitine as performance enhancers in athletes. |
| 已发布 PubMed:胆碱肌氨酸替代疗法对与严重 酸吸收不良有关的脂肪吸收不良的影响。回肠切除犬的研究。 Effect of replacement therapy with cholylsarcosine on fat malabsorption associated with severe bile acid malabsorption. Studies in dogs with ileal resection. |
| 已发布 PubMed:在卡托普利治疗的大鼠中，缓激肽诱导的浸生。 Bradykinin-induced dipsogenesis in captopril-treated rats. |
| 已发布 PubMed:果蝇隐性致死性缺口突变对黄素蛋白酶活性的影响，其抑制作用导致了缺口样表型的产生。 The effects of recessive lethal Notch mutations of Drosophila melanogaster on flavoprotein enzyme activities whose inhibitions cause Notch-like phenocopies. |
| 已发布 PubMed:海鲜中的二甲胺含量丰富 Abundance of dimethylamine in seafoods: 对 类癌症发生率的可能影响。 possible implications in the incidence of human cancer. |
| 已发布 PubMed:肌氨酸亚硝化 Nitrosation of sarcosine, 脯氨酸和4-羟基脯氨酸暴露于氮氧化物。 proline and 4-hydroxyproline by exposure to nitrogen oxides. |
| 已发布 PubMed:胍的热解产物的致突变性 Mutagenicity of pyrolysates from guanidine, 尿素 ureide, 歐洲海濱草/哺乳动物微粒体测试中发现的仲胺和多胺。 secondary amines and polyamines found by the Salmonella/mammalian-microsome test. |
| 已发布 PubMed:[on On the 问题 problems with respect to the formation of 亚硝基 n- N-nitroso compound 前体 precursors 什么时候 when 使用 using 烷基化 alkylating 代理商 agents in the 熏蒸 fumigation of 食品 食物 foodstuffs. II. 正甲基化 n- N-甲基化 methylation of 各种 various 氨基 amino acids acids by by the action of methyl 溴化物 bromide (author's 翻译 transl)]. |
| 已发布 PubMed:氨基酸和二肽摄取到仓鼠空肠和回肠的动力学 Kinetics of uptake of an amino acid and a dipeptide into hamster jejunum and ileum: 半饥饿和饥饿的影响。 the effect of semistarvation and starvation. |
| 已发布 PubMed:食品基质上非挥发性正亚硝胺的测定。 Determination of a non-volatile N-nitrosamine on a food matrix. |
| 已发布 PubMed:亲水性和亲脂性抗氧化剂存在时肌氨酸亚硝化率。 The rate of nitrosation of sarcosine in the presence of hydrophile and lipophilic antioxidants. |
| 已发布 PubMed:脯氨酸和亚硝基肌氨酸鉴定和定量测定，以及腌制肉制品中亚硝基羟脯氨酸初步研究。 Identification and quantitative determination of nitrosoproline and nitrososarcosine and preliminary investigations on nitrosohydroxyproline in cured meat products. |
| 已发布 PubMed:蛋氨酸和其他氨基酸毒性。 Toxicities of methionine and other amino acids. |
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富含花青素的草莓提取物可防止氧化应激损伤，并改善暴露于氧化剂的 皮肤成纤维细胞中的线粒体功能 an amino acid intermediate in the metabolism of choline. Sarcosine is the N-methyl derivative of glycine. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, 而 while 甘氨酸正甲基 甘氨酸 glycine-正甲基 n- N-methyl 转移酶 transferase 产生 gene率 rates sarcosine from 甘氨酸 glycine. Sarcosine is a 自然 natural 氨基 amino acid 发现 found in 肌肉 肌肉 muscles and other body 组织 tissues. In the 实验室 laboratory it 可以 may be 合成的 synthesized from chloroacetic acid and 甲胺 methylamine. Sarcosine is 自然 自然 naturally 发现 found in the 代谢 metabolism of choline to 甘氨酸 glycine. Sarcosine is 甜 sweet to the 味道 taste and 溶解 dissolves in 水 water. it It is 用过的 used in 制造业 manufacturing 可生物降解 biodegradable 表面活性剂 surfactants and 牙膏 toothpastes as 好 well as in other 应用领域 applications. Sarcosine is 无处不在 ubiquitous in 生物 biological 材料 materials and is 当下 present in 这样 such 食物 foods as 蛋 egg 蛋黄 yolks, turkey, ham, 蔬菜 vegetables, 豆类 legumes, 肌氨酸是由饮食中摄入的胆碱和蛋氨酸代谢形成的 etc. Sarcosine is formed from dietary intake of choline and from the metabolism of methionine, and is 迅速地 rapidly 降级 degraded to 甘氨酸 glycine. Sarcosine 已 has no known 毒性 toxicity, 如缺乏肌氨酸血症的表型表现所证明 as evidenced by the lack of phenotypic manifestations of sarcosinemia, an 先天 inborn 错误 error of sarcosine 代谢 metabolism. 肌氨酸血症 Sarcosinemia can result from 严重 severe 叶酸 folate 不足 deficiency 因为 be原因 cause of the 叶酸 folate 需求 requirement for the 转换 conversion of sarcosine to 甘氨酸 glycine (维基百科 Wikipedia). Sarcosine 已 has 最近 最近 recently been been identified as a 生物标志物 biomarker for 侵入性的 invasive 前列腺 prostate 癌症 cancer. it It was 发现 found to be 大大地 greatly 增加 increased 中 during 前列腺 prostate 癌症 cancer 进展 progression to 转移 metastasis and 可以 could be 检测到 detected in 尿 urine. Sarcosine 等级 levels were 也 also 增加 increased in 侵入性的 invasive 前列腺 prostate 癌症 cancer 细胞 cell 线 lines 相对的 relative to 良性 benign 前列腺 prostate 上皮的 epithelial 细胞 细胞 cells.(mid PMID: 19212411）[hmdb] 19212411) [HMDB]
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3D/INCHI