双醋酸洗必泰 chlorhexidine diacetate
1,1'-六亚甲基双 -六亚甲基 -hexamethylenebis(5-(对氯p-chlorophenyl)biguanide)diacetate

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  56-95-1氯己定二乙酸盐 56-95-1 Chlorhexidine diacetate salt
  一种通常用作眼药水消毒剂的抗菌抗菌剂 An antiseptic antibacterial agent commonly used as a disinfectant in eye drops, 除臭剂 deodorants, 面霜 creams, 和别的;漱口水中的一种有效成分，可预防和控制牙菌斑； and others; an active ingredient in mouthwash to prevent and control dental plaque;

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  ga1676洗必泰二乙酸盐水合物 GA1676 Chlorhexidine diacetate salt hydrate

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  c2511氯己定二乙酸酯> 98.0％（t） C2511 Chlorhexidine Diacetate >98.0%(T)

CAS号 CAS Number: 56-95-1 3D/INCHI echa ECHA einecs EINECS - REACH 预注册 Pre-Reg: 200-302-4 FDA UNII: 5908ZUF22Y MDL : mfcd00012532 MFCD00012532 分子量 Molecular Weight: 625.55966000 式 Formula: c26 h38 cl2 n10 o4 C26 H38 Cl2 N10 O4 生物活性总结 BioActivity Summary: 清单 listing 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:cosmetic agents   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search 已发布 PubMed: 搜索 Search NCBI: 搜索 Search   物理性质 Physical Properties: 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 沸点 Boiling Point: 699.30 °C. @ 760.00 mm 汞 Hg (est) 闪点 Flash Point: 710.00 °F. tcc TCC ( 376.70 °C. ) (est) logp（o / w） logP (o/w): 4.931（est） 4.931 (est) 溶于 Soluble in:   水 water, 254.5°C下564.5 mg / l（est） 564.5 mg/L @ 25 °C (est)   感官特性 Organoleptic Properties: 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: CosIng: 化妆品数据 cosmetic data 化妆品用途 Cosmetic Uses: 抗菌剂 antimicrobial agents 口腔护理剂 oral care agents 防腐剂 preservatives   供应商 Suppliers: American International Chemical, LLC. 醋酸氯己定 Chlorhexidine Acetate BOC Sciences 仅供实验/研究使用。 For experimental / research use only. 氯己定二乙酸盐 Chlorhexidine diacetate salt 气味 Odor: characteristic 采用 Use: 一种通常用作眼药水消毒剂的抗菌抗菌剂 An antiseptic antibacterial agent commonly used as a disinfectant in eye drops, 除臭剂 deodorants, 面霜 creams, 和别的;漱口水中的一种有效成分，可预防和控制牙菌斑； and others; an active ingredient in mouthwash to prevent and control dental plaque; 乔治·乌赫公司 George Uhe Company 双醋酸洗必泰 chlorhexidine diacetate Glentham Life Sciences 氯己定二乙酸盐水合物 Chlorhexidine diacetate salt hydrate 圣克鲁斯生物技术 Santa Cruz Biotechnology 仅供实验/研究使用。 For experimental / research use only. 氯己定二乙酸盐水合物 Chlorhexidine diacetate salt hydrate sds 西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma 仅供实验/研究使用。 For experimental / research use only. 氯己定二乙酸盐水合物双（双胍）抗菌剂 Chlorhexidine diacetate salt hydrate bis(biguanide) antimicrobial sds TCI AMERICA 仅供实验/研究使用。 For experimental / research use only. 双醋酸洗必泰> 98.0％（t） Chlorhexidine Diacetate >98.0%(T)   安全信息 Safety Information: 首选SDS Preferred SDS: 视图 View   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 腹腔内小鼠 intraperitoneal-mouse LD50 38 mg/kg British 日志 Journal of 药理 Pharmacology and 化学疗法 Chemo治疗 therapy. 卷 Vol. 9, pg。 192 Pg. 192, 1954. 静脉老鼠 intravenous-mouse LD50 25 mg/kg British 日志 Journal of 药理 Pharmacology and 化学疗法 Chemo治疗 therapy. 卷 Vol. 9, pg。 192 Pg. 192, 1954. 老鼠 oral-mouse LD50 2000 mg/kg British 日志 Journal of 药理 Pharmacology and 化学疗法 Chemo治疗 therapy. 卷 Vol. 9, pg。 192 Pg. 192, 1954. 皮肤毒性 Dermal Toxicity: 皮下老鼠 subcutaneous-mouse LD50 325 mg/kg British 日志 Journal of 药理 Pharmacology and 化学疗法 Chemo治疗 therapy. 卷 Vol. 9, pg。 192 Pg. 192, 1954. 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: cosmetic agents 推荐的双乙酸洗必泰的使用水平不超过 Recommendation for chlorhexidine diacetate usage levels up to:   不用于香水。 not for fragrance use.   推荐的双乙酸洗必泰调味剂的使用水平不超过 Recommendation for chlorhexidine diacetate flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: Epi系统 EPI System: 视图 View 临床 Clinicaltrials.gov :search 癌症引文 Cancer Citations:搜索 Search 毒理学引文 Toxicology Citations:搜索 Search 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（SRS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :9562059 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data 德国wgk WGK Germany:3 乙酸;（1e）-2- [6-[[氨基-[（e）-[氨基-（4-氯苯胺基）亚甲基]氨基]亚甲基]氨基]己基] -1- [氨基-（4-氯苯胺基）亚甲基]胍 aceticacid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine chemidplus Chemidplus:0000056951 技术 RTECS:CAS193 56-95-1的du1930000 DU1930000 for cas# 56-95-1   参考资料 References:   乙酸;（1e）-2- [6-[[氨基-[（e）-[氨基-（4-氯苯胺基）亚甲基]氨基]亚甲基]氨基]己基] -1- [氨基-（4-氯苯胺基）亚甲基]胍 aceticacid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI 加拿大国内分公司。清单 Canada Domestic Sub. List: 56-95-1 pubchem（cid） Pubchem (cid): 9562059 pubchem（sid） Pubchem (sid): 134970536   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View KEGG (GenomeNet): C18372 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): 搜索 Search 出口关税代码 Export Tariff Code: 2925.29.6000 雾度图 Haz-Map: 视图 View 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and 核心组件 core components note 没找到 None Found   潜在用途 Potential Uses:   防腐剂 preservatives   存在（自然 Occurrence (nature, 餐饮 food, 其他） other):note   自然界中找不到 not found in nature   同义词 Synonyms:   乙酸;（1e）-2- [6-[[氨基-[（e）-[氨基-（4-氯苯胺基）亚甲基]氨基]亚甲基]氨基]己基] -1- [氨基-（4-氯苯胺基）亚甲基]胍 aceticacid;(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine   芳酰胺 arlacide A   bactigras   chlorasept chlorasept 2000   chlorhexidinediacetate 1,6-bis(5-(p- chlorophenyl)biguandino biguandino)hexane diacetate 1,6-bis(p- chlorophenylbiguanido)hexane diacetate 1,6- di(4'-氯苯基二胍 -chlorophenyldiguanidino)hexane diacetate 1,1'- hexamethylene bis(5-(对氯p-chlorophenyl)biguanide) diacetate 1,1'- hexamethylenebis(5-(对氯p-chlorophenyl)biguanide) diacetate 1,1'- hexamethylenebis(5-(对氯p-chlorophenyl)biguanide), diacetate 1,1'- hexamethylenebis(5-(对氯p-chlorophenyl)biguanide)diacetate 2,2'- hexane-1,乙酸6-二基双（1-{（e）-氨基[（4-氯苯基）氨基]亚甲基}胍）乙酸酯（1 6-diylbis(1-{(E)-amino[(4-chlorophenyl)amino]methylidene}guanidine) acetate (1:2) N,N''''- hexane-1,6-二基双[n'-（4-氯苯基）（亚氨基二羰基亚氨基二酰胺）]乙酸盐（1 6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] acetate (1:2) N,n''''-1 N''''-1,6- hexanediylbis[N'-(4-chlorophenyl)(亚氨基二碳二亚甲基 imidodicarbonimidic 二酰胺 diamide)] 醋酸纤维（1 acetate (1:2)   亚氨基二碳二亚甲基 imidodicarbonimidic 二酰胺 diamide, N,n''''-1 N''''-1,6-己二基双[n'-（4-氯苯基）- 6-hexanediylbis[N'-(4-chlorophenyl)-, 醋酸纤维（1 acetate (1:2)   nolvasan 2,4,11,13- tetraazatetradecanediimidamide, N,n''-双（4-氯苯基）-3 N''-bis(4-chlorophenyl)-3,12-diimino- 12-diimino-, diacetate   文章 Articles: 已发布 PubMed:弹性义齿中掺入抗微生物剂对白念珠菌生物膜的影响。 Effect of antimicrobial agents incorporated into resilient denture relines on the Candida albicans biofilm. 已发布 PubMed:一个抗菌活性 Antibacterial activity, 表面粗糙度 surface roughness, 抗弯强度 flexural strength, 含有二乙酸氯己定/西曲肽混合物的常规胶泥的溶解度和溶解性。 and solubility of conventional luting cements containing chlorhexidine diacetate/cetrimide mixtures. 已发布 PubMed:过敏性接触性皮炎以洗必泰。 Allergic contact dermatitis to chlorhexidine. 已发布 PubMed:微孔板激光比浊法和atp生物发光测定法测定环糊精-抗菌剂-复合物的抗菌性能。 Antibacterial properties of cyclodextrin-antiseptics-complexes determined by microplate laser nephelometry and ATP bioluminescence assay. 已发布 PubMed:最大限度地减少 感染大肠杆菌o157 Minimizing human infection from Escherichia coli O157:h7使用秋葵。 H7 using GUMBOS. 已发布 PubMed:通过向基托丙烯酸树脂中添加抗菌剂而改善的弹性衬里的剥离粘合强度。 Peel bond strength of resilient liner modified by the addition of antimicrobial agents to denture base acrylic resin. 已发布 PubMed:空肠弯曲菌和适合于杀菌剂的弯曲杆菌中抗菌素耐药性的发展。 Development of antimicrobial resistance in Campylobacter jejuni and Campylobacter coli adapted to biocides. 已发布 PubMed:使用抗菌剂作为聚氨酯纳米复合材料中的有机改性剂，开发缓释抗菌尿生物材料。 Development of sustained-release antibacterial urinary biomaterials through using an antimicrobial as an organic modifier in polyurethane nanocomposites. 已发布 PubMed:泵诱导剂和多药转运蛋白cmeb的遗传变异对空肠弯曲杆菌和大肠杆菌弯曲杆菌抗药性的影响。 Effects of efflux-pump inducers and genetic variation of the multidrug transporter cmeB in biocide resistance of Campylobacter jejuni and Campylobacter coli. 已发布 PubMed:载有洗必泰盐的聚氨酯正畸链 Chlorhexidine salt-loaded polyurethane orthodontic chains: 体外释放和抗菌活性研究。 in vitro release and antibacterial activity studies. 已发布 PubMed:含氢氧化钙和洗必泰的抗菌活性对核梭形芽孢杆菌和微 有抑制作用。 Antibacterial activity of calcium hydroxide and chlorhexidine containing points against Fusobacterium nucleatum and Parvimonas micra. 已发布 PubMed:微孔板激光比浊法和atp生物发光测定法测定环糊精-防腐剂-复合物的抗菌性能。 Antimicrobial properties of cyclodextrin-antiseptics-complexes determined by microplate laser nephelometry and ATP bioluminescence assay. 已发布 PubMed:结合聚己内酯和洗必泰的熔融物理和生物学特性，获得抗菌外科单丝。 Combining in the melt physical and biological properties of poly(caprolactone) and chlorhexidine to obtain antimicrobial surgical monofilaments. 已发布 PubMed:10％的洗必泰清漆不能减少成年 口的龋齿。 10% chlorhexidine varnish did not reduce caries in an adult population. 已发布 PubMed:将二氯洗必泰掺入临时水泥中 Incorporation of chlorhexidine diacetate in provisional cements: 体外对变形链球菌的抗菌活性及其对拉伸强度的影响。 antimicrobial activity against Streptococcus mutans and the effect on tensile strength in vitro. 已发布 PubMed:氯己定掺入牙科粘合剂树脂中对树脂-牙本质键耐久性的影响。 Effect of chlorhexidine incorporation into dental adhesive resin on durability of resin-dentin bond. 已发布 PubMed:参与o空肠弯曲杆菌和大肠弯曲菌抗微生物剂的外排机制。 Involvement of efflux mechanisms in biocide resistance of Campylobacter jejuni and Campylobacter coli. 已发布 PubMed:氯己定清漆预防成 龋齿的功效 Efficacy of chlorhexidine varnish for the prevention of adult caries: 一项随机试验。 a randomized trial. 已发布 PubMed:口臭的不同治疗方式的比较。 Comparison of different treatment modalities for oral halitosis. 已发布 PubMed:犬牙前腔中双乙酸洗必泰和普罗维酮碘的术前消毒效果 Presurgical antiseptic efficacy of chlorhexidine diacetate and providone-iodine in the canine preputial cavity. 已发布 PubMed:从植入物表面的开放孔隙中施加的微孔无定形二氧化硅中控制氯己定杀菌剂的释放。 Controlled release of chlorhexidine antiseptic from microporous amorphous silica applied in open porosity of an implant surface. 已发布 PubMed:含半胱氨酸和洗必泰的口腔片剂，可降低口腔中的乙醛水平。 Buccal tablets containing cysteine and chlorhexidine for the reduction of acetaldehyde levels in the oral cavity. 已发布 PubMed:评论。含有双乙酸洗必泰/塞三酰亚胺混合物的常规玻璃离聚物水泥的抗菌活性和物理性能。 Commentary. Antibacterial activity and physical properties of conventional glass-ionomer cements containing chlorhexidine diacetate/cetrimide mixtures. 已发布 PubMed:含有双乙酸洗必泰/塞三酰亚胺混合物的常规玻璃离聚物水泥的抗菌活性和物理性能。 Antibacterial activity and physical properties of conventional glass-ionomer cements containing chlorhexidine diacetate/cetrimide mixtures. 已发布 PubMed:洗必泰和西替米德的玻璃离聚物水泥的抗菌和物理性能评价 Evaluation of the antibacterial and physical properties of glass ionomer cements containing chlorhexidine and cetrimide: 一项体外研究。 an in-vitro study. 已发布 PubMed:聚合物纳米复合树脂根端填充材料的细胞毒性。 Cytotoxicity of set polymer nanocomposite resin root-end filling materials. 已发布 PubMed:乙醇湿键合挑战了当前的抗降解策略。 Ethanol wet-bonding challenges current anti-degradation strategy. 已发布 PubMed:填充树脂释放出氟化物和洗必太。 Fluoride and chlorhexidine release from filled resins. 已发布 PubMed:氯己定并入的聚甲基丙烯酸甲酯基树脂水泥的氯己定释放和抗菌性能。 Chlorhexidine release and antibacterial properties of chlorhexidine-incorporated polymethyl methacrylate-based resin cement. 已发布 PubMed:洗必泰对 牙本质的敏感性。 Substantivity of chlorhexidine to human dentin. 已发布 PubMed:mdpb对与牙髓感染相关的厌氧菌的抗菌作用。 Antibacterial effects of MDPB against anaerobes associated with endodontic infections. 已发布 PubMed:抗菌聚氨酯纳米复合材料，使用双乙酸洗必泰作为有机改性剂。 Antibacterial polyurethane nanocomposites using chlorhexidine diacetate as an organic modifier. 已发布 PubMed:氯己定二乙酸盐制备具有抗菌活性的新型有机过有机物。 Preparation of novel organovermiculites with antibacterial activity using chlorhexidine diacetate. 已发布 PubMed:铜绿假单胞菌对双醋酸洗必泰的总体转录组反应。 Global transcriptomic response of Pseudomonas aeruginosa to chlorhexidine diacetate. 已发布 PubMed:局部递送洗必太二乙酸酯的基于聚氨酯的控释系统的特性分析。 Characterization of a polyurethane-based controlled release system for local delivery of chlorhexidine diacetate. 已发布 PubMed:甲基丙烯酸酯聚合物共混体系的体外释药研究 In vitro drug release study of methacrylate polymer blend system: 聚合物共混物组成的影响 effect of polymer blend composition, 载药量和增溶表面活性剂对药物释放的影响。 drug loading and solubilizing surfactants on drug release. 已发布 PubMed:从无定形微孔二氧化硅中控制氯己定的释放。 Controlled release of chlorhexidine from amorphous microporous silica. 已发布 PubMed:工程化钛和聚己内酯构建体，以实现 体与假肢之间的生物相容性界面。 Engineering a titanium and polycaprolactone construct for a biocompatible interface between the body and artificial limb. 已发布 PubMed:释放氯己定的基于聚甲基丙烯酸甲酯的根管封闭剂的抗菌作用。 Antibacterial effect of experimental chlorhexidine-releasing polymethyl methacrylate-based root canal sealers. 已发布 PubMed:空肠弯曲菌对鸡皮肤和肉的化学去污。 Chemical decontamination of Campylobacter jejuni on chicken skin and meat. 已发布 PubMed:sem-eds显微分析在改良的组织调理剂上浅表分布和鉴定抗真菌/抗菌剂 Superficial distribution and identification of antifungal/antimicrobial agents on a modified tissue conditioner by SEM-EDS microanalysis: 初步研究。 a preliminary study. 已发布 PubMed:义齿材料上白念珠菌生物膜形成的抑制作用。 Inhibition of Candida albicans biofilm formation on denture material. 已发布 PubMed:再矿化的发展 Development of remineralizing, 抗菌牙科材料。 antibacterial dental materials. 已发布 PubMed:具有抗菌作用的生物活性修复材料 Bio-active restorative materials with antibacterial effects: 修复牙科创新的新领域。 new dimension of innovation in restorative dentistry. 已发布 PubMed:制备 Preparation, 含氯己定的颊聚合物膜的体外表征和初步体内评估。 in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine. 已发布 PubMed:洗必泰盐的浓度依赖性聚集性质。 Concentration dependent aggregation properties of chlorhexidine salts. 已发布 PubMed:并入洗必泰的疏水性/亲水性树脂的洗必泰释放和吸水特性。 Chlorhexidine release and water sorption characteristics of chlorhexidine-incorporated hydrophobic/hydrophilic resins. 已发布 PubMed:牙科共聚物基体内负载的双乙酸洗必泰的抗菌活性和局部释放特性 Antimicrobial activity and local release characteristics of chlorhexidine diacetate loaded within the dental copolymer matrix, 乙烯乙酸乙烯酯。 ethylene vinyl acetate. 已发布 PubMed:氯己定释放的表征 Characterization of chlorhexidine-releasing, 快速设定 fast-setting, 透钙磷石骨水泥。 brushite bone cements. 已发布 PubMed:从可生物降解的可注射聚合物粘合剂中释放药物用于骨骼修复。 Drug release from injectable biodegradable polymeric adhesives for bone repair. 已发布 PubMed:含氯己定的玻璃离聚物水泥的长期抗菌作用和物理性能。 Long-term antibacterial effects and physical properties of a chlorhexidine-containing glass ionomer cement. 已发布 PubMed:用富含二氯氯己定的临时水泥固结的临时牙冠的留力和边缘渗漏。 Retention and marginal leakage of provisional crowns cemented with provisional cements enriched with chlorhexidine diacetate. 已发布 PubMed:物理化学的表征 Characterization of the physicochemical, 抗菌剂 antimicrobial agents, 设计用于医疗设备的热敏性水凝胶共聚物的药物释放特性。 and drug release properties of thermoresponsive hydrogel copolymers designed for medical device applications. 已发布 PubMed:基于壳聚糖和透明质酸伤口敷料，可在皮肤溃疡治疗中释放二乙酸洗必泰。 Wound dressings based on chitosans and hyaluronic acid for the release of chlorhexidine diacetate in skin ulcer therapy. 已发布 PubMed:从甲基丙烯酸酯共聚物体系中释放抗微生物和抗 药物 Release of antimicrobial and antiviral drugs from methacrylate copolymer system: 分子量和载药量对药物释放的影响 effect of copolymer molecular weight and drug loading on drug release. 已发布 PubMed:由基于热敏乙烯基醚的水凝胶开发的新型洗必太释放系统。 Novel chlorhexidine releasing system developed from thermosensitive vinyl ether-based hydrogels. 已发布 PubMed:添加剂和储存温度对含 他啶滴眼液的理化和微生物特性的影响。 Influence of additives and storage temperature on physicochemical and microbiological properties of eye drops containing ceftazidime. 已发布 PubMed:从多孔的甲基丙烯酸酯系统中控制双乙酸氯己定的释放 Controlled release of chlorhexidine diacetate from a porous methacrylate system: 超临界流体辅助发泡和浸渍。 supercritical fluid assisted foaming and impregnation. 已发布 PubMed:含 呋辛的滴眼液的理化和微生物学特性。 Physicochemical and microbiological properties of eye drops containing cefuroxime. 已发布 PubMed:一些实验有机硅的表征。 Characterisation of some experimental silicones. 已发布 PubMed:表面活性剂的增效作用和抗 剂的负载 Effects of solubilizing surfactants and loading of antiviral, 抗菌剂 antimicrobial agents, 和抗真菌药物对乙烯乙酸乙烯酯共聚物释放速率的影响。 and antifungal drugs on their release rates from ethylene vinyl acetate copolymer. 已发布 PubMed:从udma-tegdma树脂中控制洗必泰的释放。 Controlled release of chlorhexidine from UDMA-TEGDMA resin. 已发布 PubMed:抗菌作用 Antimicrobial effect, 体外 in vitro, 含有针对酵母菌和肠球菌球菌的根管药物的牙胶。 of gutta-percha points containing root canal medications against yeasts and Enterococcus faecalis. 已发布 PubMed:含氯己定的口香糖。临床文件。 Chlorhexidine-containing chewing gum. Clinical documentation. 已发布 PubMed:添加剂和储存温度对含有 唑啉的滴眼液的理化和微生物特性的影响。 Influence of additives and storage temperature on physicochemical and microbiological properties of eye drops containing cefazolin. 已发布 PubMed:一名无接触镜使用史的5岁男孩患有棘阿米巴角膜炎。 Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage. 已发布 PubMed:涂层医用级钛表面上的细菌和细胞细胞相容性研究。 Bacteria and cell cytocompatibility studies on coated medical grade titanium surfaces. 已发布 PubMed:用于口服洗必泰和阿昔洛韦药物的聚（乙烯-乙酸乙烯酯共聚物）共聚物基质 Poly(ethylene-co-vinyl acetate) copolymer matrix for delivery of chlorhexidine and acyclovir drugs for use in the oral environment: 药物组合的作用 effect of drug combination, 共聚物组成和涂层对药物的释放速率。 copolymer composition and coating on the drug release rate. 已发布 PubMed:乙烯乙酸乙烯酯（eva）共聚物流延膜中的药物释放 Drug release from cast films of ethylene vinyl acetate (EVA) copolymer: 1h nmr和固态13c cp / mas nmr对药物的稳定性。 Stability of drugs by 1H NMR and solid state 13C CP/MAS NMR. 已发布 PubMed:释放出氯己定的甲基丙烯酸酯牙科复合材料。 Chlorhexidine-releasing methacrylate dental composite materials. 已发布 PubMed:二乙酸氯己定和苯扎氯铵对铜绿假单胞菌的抗菌活性及其对杀生物剂残留的响应。 Antimicrobial activity of chlorhexidine diacetate and benzalkonium chloride against Pseudomonas aeruginosa and its response to biocide residues. 已发布 PubMed: 使用和不使用双乙酸洗必泰的310 nm水在pem和poly（hema-co-thfma）的半ipns中扩散的核磁共振成像。 已发布 PubMed:双胍引起的棘皮棘阿米巴变化 Biguanide-induced changes in Acanthamoeba castellanii: 电子显微镜研究。 an electron microscopic study. 已发布 PubMed:抵抗性 Resistance, 双棘皮包囊过程中双胍的吸附和双胍诱导的戊糖泄漏。 biguanide sorption and biguanide-induced pentose leakage during encystment of Acanthamoeba castellanii. 已发布 PubMed:异德拉甘氨酸囊肿成分和表面消毒剂影响h。甘氨酸孵化。 Heterodera glycines Cyst Components and Surface Disinfestants Affect H. glycines Hatching. 已发布 PubMed:用于在口腔环境中递送抗微生物和抗真菌药物的聚合物装置 A polymeric device for delivery of anti-microbial and anti-fungal drugs in the oral environment: 温度和介质对药物释放速率的影响。 effect of temperature and medium on the rate of drug release. 已发布 PubMed: 含有芦荟的滴眼液技术（芦荟 aloe arborescens mill .-- liliaceae）和既含有芦荟又含有硫酸新霉素的滴眼液技术。 已发布 PubMed:邻苯二甲醛的作用 Effects of ortho-phthalaldehyde, 戊二醛和双乙酸洗必泰在具有改良通透性的螯合分枝杆菌和脓肿分枝杆菌菌株上。 glutaraldehyde and chlorhexidine diacetate on Mycobacterium chelonae and Mycobacterium abscessus strains with modified permeability. 已发布 PubMed:树脂改性的玻璃离聚物与洗必泰的抗菌和物理性能。 Antibacterial and physical properties of resin modified glass-ionomers combined with chlorhexidine. 已发布 PubMed:载药的壳聚糖微球制备的洗必泰口腔含片的配方和体内评价。 Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres. 已发布 PubMed:用于口腔内递送抗真菌剂的聚合物系统。 A polymeric system for the intra-oral delivery of an anti-fungal agent. 已发布 PubMed:棘皮棘皮虫 Encystation in Acanthamoeba castellanii: 抗微生物剂的发展。 development of biocide resistance. 已发布 PubMed:发展 Development of 抵抗性 resistance to 双醋酸洗必泰 chlorhexidine diacetate in 假单胞菌 Pseudomonas 绿脓杆菌 aeruginosa and the 影响 effect of a "剩余的 residual" 浓度 concentration. 已发布 PubMed:Stutzeri假单胞菌对双乙酸洗必泰和氯化十六烷基吡啶有抗性。 Outer membrane changes in Pseudomonas stutzeri resistant to chlorhexidine diacetate and cetylpyridinium chloride. 已发布 PubMed:原位模型的微生物学方面，以研究抗菌剂对牙菌斑生态学的影响。 Microbiological aspects of an in situ model to study effects of antimicrobial agents on dental plaque ecology. 已发布 PubMed:口腔抗菌剂对龋齿生物的最低抑制浓度。 The minimum inhibitory concentration of oral antibacterial agents against cariogenic organisms. 已发布 PubMed:从中空尼龙纤维中释放出的双乙酸洗必泰的细胞毒性和致畸性。 Cytotoxicity and teratogenicity of chlorhexidine diacetate released from hollow nylon fibres. 已发布 PubMed:棘棘皮分化过程中对杀生物剂的抗性出现。 Emergence of resistance to biocides during differentiation of Acanthamoeba castellanii. 已发布 PubMed:抗菌剂对牲畜废物排放的影响。 Effect of antimicrobial agents on livestock waste emissions. 已发布 PubMed:斯图氏假单胞菌耐洗必泰分离株的细胞学变化。 Cytological changes in chlorhexidine-resistant isolates of Pseudomonas stutzeri. 已发布 PubMed:氯己定从室温聚合的甲基丙烯酸酯体系中释放出来。 Chlorhexidine release from room temperature polymerising methacrylate systems. 已发布 PubMed:液晶结构对洗必泰二乙酸酯释放的影响。 The effect of liquid crystalline structure on chlorhexidine diacetate release. 已发布 PubMed:比较斯图氏假单胞菌和铜绿假单胞菌对抗菌剂的反应。 Comparative responses of Pseudomonas stutzeri and Pseudomonas aeruginosa to antibacterial agents. 已发布 PubMed:3he离子束分析水吸收和药物传递。 3He ion-beam analysis of water uptake and drug delivery. 已发布 PubMed:克氏假单胞菌对双乙酸洗必泰和氯化十六烷基吡啶的抗药性的发展以及抗生素敏感性的变化。 Development of resistance to chlorhexidine diacetate and cetylpyridinium chloride in Pseudomonas stutzeri and changes in antibiotic susceptibility. 已发布 PubMed:使用转座子编码的儿茶酚2快速评估杀菌活性 Rapid evaluation of biocidal activity using a transposon-encoded catechol 2,来自恶臭假单胞菌的3-双加氧酶。 3-dioxygenase from Pseudomonas putida. 已发布 PubMed:南方根结 和异形藻甘氨酸体外测定，用于检测 拮抗真菌化合物。 In-vitro Assays of Meloidogyne incognita and Heterodera glycines for Detection of Nematode-antagonistic Fungal Compounds. 已发布 PubMed:抗菌牙科清漆对前列腺素水平的影响 Effect of an antibacterial dental varnish on the levels of prostanoids, 白三烯b4 leukotriene B4, 和龈沟液中明串球菌介素-1β。 and interleukin-1 beta in gingival crevicular fluid. 已发布 PubMed:X射线显微分析双胍处理过的棘皮棘阿米藻中氯和磷的含量。 X-ray microanalysis of chlorine and phosphorus content in biguanide-treated Acanthamoeba castellanii. 已发布 PubMed:使用离体测试在皮肤上测试的杀菌剂的抗菌功效。 Antimicrobial efficacy of biocides tested on skin using an ex-vivo test. 已发布 PubMed:malthus-at系统用于评估通透剂对铜绿假单胞菌抗菌剂活性的功效。 Use of the Malthus-AT system to assess the efficacy of permeabilizing agents on the activity of antibacterial agents against Pseudomonas aeruginosa. 已发布 PubMed:氯己定双乙酸盐对小酸模/羊酸模/红酸模微生物的影响 Effects of chlorhexidine diacetate on ruminal microorganisms. 已发布 PubMed:含氯己定/百里酚的清漆对龈沟液中前列腺素e2水平的影响。 Effect of a chlorhexidine/thymol-containing varnish on prostaglandin E2 levels in gingival crevicular fluid. 已发布 PubMed:流式细胞仪和噬菌斑测定法测定了杀生物剂对卡氏棘阿米巴的影响。 Effects of biocides on Acanthamoeba castellanii as measured by flow cytometry and plaque assay. 已发布 PubMed:五种局部应用的洁牙剂可抑制大鼠的龋齿和牙菌斑。 Caries and plaque inhibition in rats by five topically applied dentifrices. 已发布 PubMed:双胍类对卡氏棘孢子滋养体和囊肿作用机理的一些方面。 Aspects of the mechanisms of action of biguanides on trophozoites and cysts of Acanthamoeba castellanii. 已发布 PubMed:双胍类对刺五加囊肿和滋养体的致死作用。 The lethal effects of biguanides on cysts and trophozoites of Acanthamoeba castellanii. 已发布 PubMed:氯己定对小马中细菌和睑板香柳叶菜的影响。 Effects of potentiated chlorhexidine on bacteria and tarsocrural joints in ponies. 已发布 PubMed:酵母细胞壁在改变细胞对双乙酸洗必泰的反应中可能发挥的作用。 The possible role of yeast cell walls in modifying cellular response to chlorhexidine diacetate. 已发布 PubMed:在细菌脱盐模型中通过洗必泰和氟化物清漆保护牛牙釉质和牙本质。 Protection of bovine enamel and dentine by chlorhexidine and fluoride varnishes in a bacterial demineralization model. 已发布 PubMed:洗必泰清漆对牙裂斑块中内生升麻基因型的影响。 Effect of chlorhexidine varnish on Actinomyces naeslundii genospecies in plaque from dental fissures. 已发布 PubMed:抗牙龈炎口香糖的功效。 The efficacy of an anti-gingivitis chewing gum. 已发布 PubMed:乙胺丁醇增强双乙酸洗必泰和氯化十六烷基吡啶对分枝杆菌的作用。 Potentiation of the effects of chlorhexidine diacetate and cetylpyridinium chloride on mycobacteria by ethambutol. 已发布 PubMed:X射线能量色散分析研究双乙酸铜氯己定和氯化十六烷基吡啶在铜绿假单胞菌f116上的分布。 Energy dispersive analysis of X-rays study of the distribution of chlorhexidine diacetate and cetylpyridinium chloride on the Pseudomonas aeruginosa bacteriophage F116. 已发布 PubMed:洗必泰酵母细胞的X射线显微分析。 X-ray microanalysis of chlorhexidine-treated cells of Saccharomyces cerevisiae. 已发布 PubMed:喷雾消毒后的抗菌藻酸盐与石膏的相容性。 Gypsum compatibility of antimicrobial alginates after spray disinfection. 已发布 PubMed:洗必泰0.05％洗必泰对马的趾香柳叶菜的影响。 Effects of 0.05% chlorhexidine lavage on the tarsocrural joints of horses. 已发布 PubMed: 单核细胞增生性李斯特菌对葡萄糖的吸收和片球菌素 pediocin jd的抑制作用。 已发布 PubMed:接触这些消毒剂的牙科学生和剧院工作 员对熊果的洗必泰和十六烷基氯化吡啶鎓的敏感性。 The sensitivity to chlorhexidine and cetyl pyridinium chloride of staphylococci on the hands of dental students and theatre staff exposed to these disinfectants. 已发布 PubMed:乙酸洗必泰香柳叶菜腔内灌洗对健康犬窒息的影响。 Effects of intra-articular chlorhexidine diacetate lavage on the stifle in healthy dogs. 已发布 PubMed:二乙酸氯己定和氯化十六烷基吡啶对酿酒酵母全细胞和原生质体的影响 Effects of chlorhexidine diacetate and cetylpyridinium chloride on whole cells and protoplasts of Saccharomyces cerevisiae. 已发布 PubMed:分娩时通过阴道洗必泰消毒预防与b组链球菌有关的新生儿过多发病。瑞典洗必泰研究小组。 Prevention of excess neonatal morbidity associated with group B streptococci by vaginal chlorhexidine disinfection during labour. The Swedish Chlorhexidine Study Group. 已发布 PubMed:酸洗必泰对白念珠菌的影响 Effects of chlorhexidine diacetate on Candida albicans, C。 glabrata glabrata和酿酒酵母。 已发布 PubMed:四种0.05％的洗必泰双乙酸盐制剂对犬伤口愈合的影响。 Effects of four preparations of 0.05% chlorhexidine diacetate on wound healing in dogs. 已发布 PubMed:联合洗必泰的效果 The effect of a combination of chlorhexidine diacetate, 氟化钠和木糖醇对在7天实验期内不进行机械牙齿清洁的军校学员的牙菌斑湿重和牙周指数评分的影响。 sodium fluoride and xylitol on plaque wet weight and periodontal index scores in military academy cadets refraining from mechanical tooth cleaning for 7-day experimental periods. 已发布 PubMed:14c-氯己定二乙酸盐和14c-苄醇的细菌吸收以及苯氧乙醇和唑他汀的影响 Bacterial uptake of 14C-chlorhexidine diacetate and 14C-benzyl alcohol and the influence of phenoxyethanol and azolectin: 研究革兰氏阴性细菌。 studies with gram-negative bacteria. 已发布 PubMed:氯己定双乙酸盐和苯氧乙醇的作用机理以及对革兰氏阴性菌的联合作用。 Mechanism of action of chlorhexidine diacetate and phenoxyethanol singly and in combination against gram-negative bacteria. 已发布 PubMed:zn（2 +）-氯己定和zn（2 +）-十六烷基吡啶鎓氯化物对部分脱盐大鼠龋齿发生率的综合影响。 Combined effects of Zn(2+)-chlorhexidine and Zn(2+)-cetylpyridinium chloride on caries incidence in partially desalivated rats. 已发布 PubMed:犬爪子手术准备的手术磨砂膏和消毒液的评价。 Evaluation of surgical scrub and antiseptic solutions for surgical preparation of canine paws. 已发布 PubMed:接触时间和洗必泰清漆浓度对齿间牙菌斑中变形链球菌的影响 Influence of contact time and concentration of chlorhexidine varnish on mutans streptococci in interproximal dental plaque. 已发布 PubMed:体内生物发光 In vivo bioluminescence: 从事研究和行业研究的手机记者。 a cellular reporter for research and industry. 已发布 PubMed:皮肤拭子中双乙酸洗必泰引起的过敏性接触性皮炎。 Allergic contact dermatitis from chlorhexidine diacetate in a skin swab. 已发布 PubMed:绷带和局部用药。 Bandages and topical agents. 已发布 PubMed:洗必泰清漆对 牙菌斑的影响 Effects of varnishes containing chlorhexidine on the human dental plaque flora. 已发布 PubMed:氯己定的口服控释递送系统的开发和体外评估。 Development and in vitro evaluation of an intra-oral controlled-release delivery system for chlorhexidine. 已发布 PubMed:大肠杆菌和铜绿假单胞菌对14c-氯己定双乙酸酯的吸收，并由唑菌素释放。 Uptake of 14C-chlorhexidine diacetate to Escherichia coli and Pseudomonas aeruginosa and its release by azolectin. 已发布 PubMed:醋酸氯己定对 体牙菌斑的影响 Effects of sustained-release chlorhexidine acetate on the human dental plaque flora. 已发布 PubMed:二乙酸氯己定和聚维酮碘对狗伤口愈合的影响 Effects of chlorhexidine diacetate and povidone-iodine on wound healing in dogs. 已发布 PubMed:双醋酸洗必泰和聚维酮碘对犬胚胎成纤维细胞和金黄熊果的细胞毒性。 Chlorhexidine diacetate and povidone-iodine cytotoxicity to canine embryonic fibroblasts and Staphylococcus aureus. 已发布 PubMed:枯草芽孢杆菌孢子对洗必泰的抗药性机理 Mechanism of resistance of Bacillus subtilis spores to chlorhexidine. 已发布 PubMed:医院分离的革兰氏阴性菌对防腐剂和消毒剂的敏感性。 Comparative susceptibility of hospital isolates of gram-negative bacteria to antiseptics and disinfectants. 已发布 PubMed:生长速度和营养限制对大肠杆菌对双乙酸洗必泰的敏感性的影响。 Influence of specific growth rate and nutrient limitation upon the sensitivity of Escherichia coli towards chlorhexidine diacetate. 已发布 PubMed:代谢通量在大肠杆菌中央有氧代谢途径中的重新分布大肠埃希氏菌突变株，具有用于合成乙酸异戊酯的acka-pta和poxb途径缺失。 Quenching of the antibacterial activity of chlorhexidine and benzalkonium by Letheen broth and Letheen agar in relation to wild-type and envelope mutant strains of gram-negative bacteria. 已发布 PubMed:逆转双乙酸洗必泰对斯图亚特氏菌细胞的表面作用。 Reversal of the surface effects of chlorhexidine diacetate on cells of Providencia stuartii. 已发布 PubMed:普萘洛尔效能的Comparison of the potency of d-propranolol, 洗必泰试验中的洗必泰和壬氧酚9。 chlorhexidine and nonoxynol-9 in the Sander-Cramer test. 已发布 PubMed:比较壬诺醇9和洗必泰对胚芽的作用。 Comparison of the action of nonoxynol-9 and chlorhexidine on sperm. 已发布 PubMed:杀菌剂对斯图亚特氏菌的洗必泰敏感和耐洗必泰菌株的细胞表面变化。 Antiseptic-induced changes in the cell surface of a chlorhexidine-sensitive and a chlorhexidine-resistant strain of Providencia stuartii. 已发布 PubMed:环境药物浓度与抑制微生物在表面上生长的相关性。 Correlation of microenvironmental drug concentration with inhibition of growth of microorganisms on surfaces. 已发布 PubMed:预先注入2-丙醇饱和的棉签后，环氧丙烷和洗必太二乙酸盐溶液的灭菌能力。 The sterilizing capacity of propylene oxide and chlorhexidine diacetate solutions upon pre-injection swabs saturated with propan-2-ol. 已发布 PubMed:比较抗菌活性 Comparative antimicrobial activity, 体外和体内 in vitro and in vivo, 软正氯胺系统和洗必泰 of soft N-chloramine systems and chlorhexidine. 已发布 PubMed:洗必泰稳定腹足动物血色素的整个分子。 Stabilization of whole molecules of gastropodan haemocyanins by chlorhexidine. 已发布 PubMed:一些一价阳离子的影响 The influence of some monovalent cations, 在不同浓度下，对双乙酸洗必泰和（乙氧基）5-辛基苯酚有活性[过程]。 at various concentrations upon the activity of chlorhexidine diacetate and (ethoxy)5 octyl phenol [proceedings]. 已发布 PubMed:双醋酸洗必泰对假 的体外活性。 In vitro activity of chlorhexidine diacetate against pseudorabies virus. 已发布 PubMed:硼酸四苯酯重量法测定洗必泰。 Gravimetric determination of chlorhexidine using tetraphenylborate ion. 已发布 PubMed:洗必泰及有关化合物的表面化学研究 Surface-chemical studies on chlorhexidine and related compounds: 一世。对空气水的影响 I. Effects at air-water, 正己烷水 n-hexane-water, 和羟基磷灰石-水界面。 and hydroxyapatite-water interfaces. 已发布 PubMed:抗菌防腐剂可溶血红细胞。 iv。氯己定二乙酸酯的溶血活性。 Hemolysis of erythrocytes by antibacterial preservatives. IV. Hemolytic activity of chlorhexidine diacetate. 已发布 PubMed:细胞学方面的双醋酸洗必泰的作用方式。 CYTOLOGICAL ASPECTS OF THE MODE OF ACTION OF CHLORHEXIDINE DIACETATE. 已发布 PubMed:影响 EFFECT OF 洗必泰 CHLORHEXIDINE 双乙酸盐 DIACETATE ON "原生质体 PROTOPLASTS" and AND 原生质球 SPHEROPLASTS OF 大肠埃希氏菌 ESCHERICHIA 大肠杆菌 COLI, 巨大芽孢杆菌原生质体与金黄熊果的革兰氏染色反应 PROTOPLASTS OF BACILLUS MEGATERIUM AND THE GRAM STAINING REACTION OF STAPHYLOCOCCUS AUREUS. 已发布 PubMed:预防阴道手术后的尿路感染。 Prevention of urinary tract infections after vaginal surgery.

笔记 Notes: 一种消毒剂和局部抗感染剂，还可以用作漱口水以预防口腔菌斑。 a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.