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类别 Category:viscosity controlling agents
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 熔点 Melting Point: | 110.00 °C. @ 760.00 mm 汞 Hg
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| 沸点 Boiling Point: | 335.12 °C. @ 760.00 mm 汞 Hg (est)
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| 闪点 Flash Point: | 314.00 °F. tcc TCC ( 156.50 °C. ) (est)
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| logp（o / w） logP (o/w): | 4.235（est） 4.235 (est) |
| 溶于 Soluble in: |
| | 水 water, 27.72 mg / l @ 25°C（est） 27.72 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | viscosity controlling agents |
| 推荐的月桂酰胺使用量最高为 Recommendation for lauramide usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 推荐的月桂酰胺风味剂的使用水平最高为 Recommendation for lauramide flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
| | dodecanamide |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| pubchem（cid） Pubchem (cid): | 14256 |
| pubchem（sid） Pubchem (sid): | 134979945 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
| | viscosity controlling agents |
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| | 十二酰胺 dodecamide | | | dodecanamide | | | 十二酰胺 dodecylamide | | | 月桂酸 lauric acid amide | | | 月桂酸 lauric amide | | | 月桂酰酰胺 lauroylamide | | | 月桂基 lauryl amide |
文章 Articles:
| 已发布 PubMed:酰基二胺新系列作为潜在的抗菌剂和抗真菌剂的合成和生物学评估。 Synthesis and biological evaluation of a new series of N-acyldiamines as potential antibacterial and antifungal agents. |
| 已发布 PubMed:X射线晶体学分析修订了橙花酰胺运输抑制剂hpa-12的立体化学。 Revised stereochemistry of ceramide-trafficking inhibitor HPA-12 by X-ray crystallography analysis. |
| 已发布 PubMed:阴道加德纳菌生物膜对天然抗菌素枯草杆菌蛋白酶的敏感性 Susceptibility of Gardnerella vaginalis biofilms to natural antimicrobials subtilosin, ε-聚赖氨酸 ε-poly-L-lysine, 和月桂酰胺精氨酸乙酯。 and lauramide arginine ethyl ester. |
| 已发布 PubMed:基于evoh释放Lae的抗菌食品包装膜。 Antimicrobial food packaging film based on the release of LAE from EVOH. |
| 已发布 PubMed:双头离子表面活性剂与带相反电荷的聚电解质相互作用对体外染料从油核纳米胶囊中释放的影响 Influence of dicephalic ionic surfactant interactions with oppositely charged polyelectrolyte upon the in vitro dye release from oil core nanocapsules. |
| 已发布 PubMed:沙眼衣原体联合选择gbf1和cert获得宿主鞘磷脂，以在细胞内发育过程中发挥不同作用。 Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development. |
| 已发布 PubMed:证书依赖型橙花酰胺运输抑制剂hpa-12及其类似物的简便实用合成。 Expedient and practical synthesis of CERT-dependent ceramide trafficking inhibitor HPA-12 and its analogues. |
| 已发布 PubMed:铜绿假单胞菌群体感应抑制剂检测有效筛选系统的构建及其在生物自显影薄层色谱中的应用。 Construction of an effective screening system for detection of Pseudomonas aeruginosa quorum sensing inhibitors and its application in bioautographic thin-layer chromatography. |
| 已发布 PubMed:在空气/溶液界面上不等价吸附新型二头铵表面活性剂的实验和理论方法。 Experimental and theoretical approach to nonequivalent adsorption of novel dicephalic ammonium surfactants at the air/solution interface. |
| 已发布 PubMed:使用高效液相色谱-电喷雾电离串联质谱分析橙花酰胺-1-磷酸水平。 Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels. |
| 已发布 PubMed:吡咯烷 Pyripyropenes, 与α-吡喃酮和吡啶部分缀合的真菌倍半萜 fungal sesquiterpenes conjugated with alpha-pyrone and pyridine moieties, 对 脐静脉内皮细胞具有抗血管生成活性。 exhibits anti-angiogenic activity against human umbilical vein endothelial cells. |
| 已发布 PubMed:树突状对超分子自组装的影响 Dendritic effect on supramolecular self-assembly: 聚集诱导的具有强荧光发射的有机凝胶。 organogels with strong fluorescence emission induced by aggregation. |
| 已发布 PubMed:dna在液体/固体界面的吸附。 DNA adsorption at liquid/solid interfaces. |
| 已发布 PubMed:橙花酰胺转运蛋白（cert）功能的降低会改变uvb照射后鞘磷脂的产生。 Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation. |
| 已发布 PubMed:溶血磷脂酰基转移酶拮抗剂ci-976抑制了小囊泡出芽的后期步骤。 The lysophospholipid acyltransferase antagonist CI-976 inhibits a late step in COPII vesicle budding. |
| 已发布 PubMed:80度伯胺的高选择性酶动力学拆分 Highly selective enzymatic kinetic resolution of primary amines at 80 degrees C: 羧酸及其乙酯作为酰基供体的比较研究。 a comparative study of carboxylic acids and their ethyl esters as acyl donors. |
| 已发布 PubMed:使用酰基转移酶抑制剂来阻止er和高尔基体之间的水泡运输。 Use of acyltransferase inhibitors to block vesicular traffic between the ER and Golgi complex. |
| 已发布 PubMed:基于简单正羟基烷基酰胺的触变有机凝胶 Thixotropic organogels based on a simple N-hydroxyalkyl amide: 流变和老化性能。 rheological and aging properties. |
| 已发布 PubMed:[细胞内橙花酰胺运输的分子机制证明]。 [The molecular machinery CERT for intracellular trafficking of ceramide]. |
| 已发布 PubMed:与高尔基体复合体相关的新型ci-976敏感的溶血磷脂酰基转移酶的特征 Characterization of a novel CI-976-sensitive lysophospholipid acyltransferase that is associated with the Golgi complex. |
| 已发布 PubMed:高尔基体溶血磷脂酰基转移酶的抑制作用诱导膜小管形成和逆行运输。 Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking. |
| 已发布 PubMed:新型橙花酰胺运输抑制剂的立体选择性合成及其构效关系。 （1r Stereoselective synthesis and structure-activity relationship of novel ceramide trafficking inhibitors. (1R,3r）-正-（3-羟基-1-羟甲基-3-苯基丙基）十二烷酰胺及其类似物。 3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide and its analogues. |
| 已发布 PubMed:催化 Catalytic, 酰基酰亚胺酯的不对称曼尼希型反应 asymmetric Mannich-type reactions of N-acylimino esters: 反应性 reactivity, 非对映和对映选择性 diastereo- and enantioselectivity, 及其在合成n-酰化氨基酸衍生物中的应用。 and application to synthesis of N-acylated amino acid derivatives. |
| 已发布 PubMed:月桂酸二乙醇胺缩合物（CAS号120-40-1）在f344 / n大鼠和b6c3f1小鼠中的ntp毒理学和致癌作用研究（皮肤研究）。 NTP Toxicology and Carcinogenesis Studies of Lauric Acid Diethanolamine Condensate (CAS NO. 120-40-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies). |
| 已发布 PubMed:催化 Catalytic, 阿特拉斯雪松皮油雪松libani亚种。大西洋皮油雪松libani var。大西洋雪松皮油松大西洋雪松皮油从雪松的皮中获得的挥发油 asymmetric Mannich-type reactions of N-acylimino esters for direct formation of N-acylated amino acid derivatives. Efficient synthesis of a novel inhibitor of ceramide trafficking, hpa-12。 HPA-12. |
| 已发布 PubMed:从内质网到鞘磷脂合成部位的橙花酰胺转运抑制剂。 A novel inhibitor of ceramide trafficking from the endoplasmic reticulum to the site of sphingomyelin synthesis. |
| 已发布 PubMed:用于细胞膜破坏的ph响应假肽。 pH-responsive pseudo-peptides for cell membrane disruption. |
| 已发布 PubMed:气相色谱-质谱检测法测定三甲基甲硅烷基衍生物脂肪酸酰胺 Determination of fatty acid amides as trimethylsilyl derivatives by gas chromatography with mass spectrometric detection. |
| 已发布 PubMed:体内和体外处置2 In vitro and in vivo disposition of 2,2-二甲基-n-（2 2-dimethyl-N-(2,4,6-三甲氧基苯基）十二烷酰胺（ci-976）。新型五碳裂解代谢产物的鉴定 6-trimethoxyphenyl)dodecanamide (CI-976). Identification of a novel five-carbon cleavage metabolite in rats. |
| 已发布 PubMed:月桂酰胺二乙醇胺吸收 Lauramide diethanolamine absorption, 代谢 metabolism, 口服后大鼠和小鼠体内的化学和处置 and disposition in rats and mice after oral, 静脉 intravenous, 和皮肤给药。 and dermal administration. |
| 已发布 PubMed:肝微粒体将月桂酰胺二乙醇胺羟化。 Hydroxylation of lauramide diethanolamine by liver microsomes. |
| 已发布 PubMed:细胞色素p450 4a1和细胞色素p4504a1 / nadph-p450还原酶融合蛋白对脂肪酸识别和ω-羟基化作用。 Fatty acid discrimination and omega-hydroxylation by cytochrome P450 4A1 and a cytochrome P4504A1/NADPH-P450 reductase fusion protein. |
| 已发布 PubMed:酰基可可的作用 The effect of acyl CoA: 胆固醇酰基转移酶对摄取的抑制作用 cholesterol acyltransferase inhibition on the uptake, 仓鼠小肠的酯化和胆固醇分泌。 esterification and secretion of cholesterol by the hamster small intestine. |
| 已发布 PubMed:2的测定 Determination of 2,2-二甲基-n-（2 2-dimethyl-N-(2,4,6-三甲氧基苯基）十二烷酰胺 6-trimethoxyphenyl) dodecanamide, ci-976 CI-976, 反相高效液相色谱法测定大鼠血浆中 in rat plasma by reversed-phase high-performance liquid chromatography. |
| 已发布 PubMed:基于流动级理论的固体腈和叔酰胺的溶解度预测。 Solubility predictions for solid nitriles and tertiary amides based on the mobile order theory. |
| 已发布 PubMed:表达铜绿假单胞菌毒力基因所需的自诱导子的结构。 Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. |
| 已发布 PubMed:酰基辅酶a的生物特征研究 Biodisposition studies with the acyl-coenzyme A: 胆固醇酰基转移酶抑制剂2 cholesterol acyltransferase inhibitor 2,2-二甲基-n-（2 2-dimethyl-N-(2,4,6-三甲氧基苯基）十二烷酰胺 6-trimethoxyphenyl) dodecanamide, ci-976。 CI-976. |
| 已发布 PubMed:2的测定 Determination of 2,2-二甲基-n-（2 2-dimethyl-N-(2,4,6-三甲氧基苯基）-十二烷酰胺 6-trimethoxyphenyl)-dodecanamide, 脂质调节剂 a lipid regulator, 反相高效液相色谱法检测大鼠血浆和肠系膜淋巴液 in rat plasma and mesenteric lymph by reversed-phase high-performance liquid chromatography. |
| 已发布 PubMed:促进了纤维酸酯和酰胺对两种模型甾体的转运。 Facilitated transport of two model steroids by esters and amides of clofibric acid. |
| 已发布 PubMed:聚维酮碘和伤口愈合的评估。 An appraisal of povidone-iodine and wound healing. |
| 已发布 PubMed:氮杂胺和六亚甲基月桂酰胺在兔眼中的毒理作用和西咪替丁渗透增强的比较。 Comparison of azone and hexamethylene lauramide in toxicologic effects and penetration enhancement of cimetidine in rabbit eyes. |
| 已发布 PubMed:酰基辅酶A抑制剂 Inhibitors of acyl-CoA:胆固醇酰基转移酶。 1.一系列新型脂肪酸苯胺降胆固醇药的鉴定与构效关系。 cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. |
| 已发布 PubMed:ci-976的Comparison of CI-976, 防霉剂 an ACAT inhibitor, 并选择了降脂剂来增强股和胸主动脉病变的抗动脉粥样硬化活性。生化 and selected lipid-lowering agents for antiatherosclerotic activity in iliac-femoral and thoracic aortic lesions. A biochemical, 形态的 morphological, 和形态计量学评估。 and morphometric evaluation. |
| 已发布 PubMed:酰基辅酶的代谢 Metabolism of the acyl-CoA:胆固醇酰基转移酶抑制剂2 cholesterol acyltransferase inhibitor 2,2-二甲基-n-（2 2-dimethyl-N-(2,4,大鼠和猴子体内的6-三甲氧基苯基）十二烷酰胺Ω/β氧化途径。 6-trimethoxyphenyl)dodecanamide in rat and monkey. Omega-/beta-oxidation pathway. |
| 已发布 PubMed:在大鼠三明治皮瓣模型中经皮和全身处理六亚甲基月桂酰胺及其对氢化可的松的渗透增强作用。 Percutaneous and systemic disposition of hexamethylene lauramide and its penetration enhancement effect on hydrocortisone in a rat sandwich skin-flap model. |
| 已发布 PubMed:叶绿体偶联因子1的酶促活性不需要核苷酸位点的旋转。 Rotation of nucleotide sites is not required for the enzymatic activity of chloroplast coupling factor 1. |
| 已发布 PubMed:接触对洗发香波中的椰油酰胺和月桂酰胺过敏的 群。 Contact allergy to cocamide DEA and lauramide DEA in shampoos. |
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3D/INCHI