oleamide
(z)十八碳九烯酸酰胺 (Z)-octadec-9-enoic acid amide

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  • American International Chemical, LLC.
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    Aic是韦斯特伯鲁 AIC is a Westborough, 马基础上通过iso ISO认证的销售和营销公司,为食品 , 制药业 pharmaceutical, 营养的 nutritional, 个 护理 personal care, 生物技术 biotech, 自1972年以来进入北美市场和工业市场。我们的成功是建立在基于客户需求的企业文化之上的 and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, 以及与致力于北美市场严苛和要求的全球制造商的合作伙伴关系。我们的销售代表团队 along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, 加上我们战略性地位于仓库中的网络,随时可以在您需要的时候提供产品。 along with our network of strategically located warehouses are ready to supply product when and where you need it.
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    olefib oleamide finawax-o磁珠 OLEFIB Oleamide Finawax-O Beads
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    产品 Product(s):
    301-02-0油酰胺97% 301-02-0 Oleicamide 97%
    A 脑 brain lipid that 诱导 induces 生理 physiological 睡觉 sleep at 纳摩尔 nanomolar 数量 quantities 什么时候 when 注入的 injected 进入 into 老鼠 rats. 这个 This lipid 可以 may 代表 repr
CAS号 CAS Number: 301-02-0Picture of molecule3D/INCHI
其他 Other:181057-55-6
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:206-103-9
FDA UNII:7L25QK8BWO
nikkaji网站 Nikkaji Web:J36.613G
MDL :mfcd00053638 MFCD00053638
XlogP3-AA:6.60(est) 6.60 (est)
分子量 Molecular Weight:281.48315000
式 Formula:c18 h35 n o C18 H35 N O
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:opacifying agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
dg sante食品接触材料 DG SANTE Food Contact Materials:oleamide
fda mainterm(iaufc) FDA Mainterm (IAUFC):301-02-0 ; OLEAMIDE

 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
沸点 Boiling Point: 433.34 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 421.00 °F. tcc TCC ( 215.90 °C. ) (est)
logp(o / w) logP (o/w): 6.882(est) 6.882 (est)
溶于 Soluble in:
 水 water, 0.04591 mg / l @ 25°c(est) 0.04591 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: opacifying agents
粘度控制剂 viscosity controlling agents
 
供应商 Suppliers:
American International Chemical, LLC.
油酰胺finawax-o磁珠 Oleamide Finawax-O Beads
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
油酰胺97% Oleicamide 97%
气味 Odor: characteristic
采用 Use: A 脑 brain lipid that 诱导 induces 生理 physiological 睡觉 sleep at 纳摩尔 nanomolar 数量 quantities 什么时候 when 注入的 injected 进入 into 老鼠 rats. 这个 This lipid 可以 may 代表 repr
花王公司 Kao Corporation
脂肪酰胺 FATTY AMIDE O-N
气味 Odor: characteristic
采用 Use: 使用润滑剂 Lubricant use, 抗粘连剂和防滑剂。 anti-blocking agent and slipping agent.
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
油酰胺≥99% Oleamide ≥99%
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
opacifying agents
推荐的油酰胺使用量最高为 Recommendation for oleamide usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐的油酰胺风味剂使用量最高为 Recommendation for oleamide flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
欧洲食品安全局(efsa EFSA)参考 :

甲基支链和线性c14-c18烷酰胺混合物的安全性评估 Safety assessment of the mixture of methyl-branched and linear C14�C18 alkanamides, 源自脂肪酸 derived from fatty acids, for use in food contact materials
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
nlm NLM有害物质数据库 :搜索 Search
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
EPA物质注册服务(tsca TSCA) :301-02-0
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :5283387
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
(z)-十八烷基-9-酰胺 (Z)-octadec-9-enamide
chemidplus Chemidplus:0000301020
 
参考资料 References:
 (z)-十八烷基-9-酰胺 (Z)-octadec-9-enamide
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:301-02-0
pubchem(cid) Pubchem (cid):5283387
pubchem(sid) Pubchem (sid):134975607
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
用于食品接触物质的fda间接添加剂 FDA Indirect Additives used in Food Contact Substances:视图 View
CHEBI:视图 View
CHEMBL:视图 View
KEGG (GenomeNet):C19670
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB02117
食物 FooDB:FDB012436
雾度图 Haz-Map:视图 View
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在 有力的 Potential 搅拌机 Blenders and core components note
没找到 None Found
 
潜在用途 Potential Uses:
 opacifying agents
 粘度控制剂 viscosity controlling agents
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 Adogen adogen 73
 臂章 armo滑 slip cp CP
 克罗酰胺 crodamide O
 克罗酰胺 crodamide OR
 脂肪的 fatty amide o-n O-N
(9Z)-octadec-9-enamide
(Z)-octadec-9-enamide
(Z)-octadec-9-enoic acid amide
cis-9,10-octadecanamide
(9Z)-9-octadecenamide
(Z)-9-octadecenamide
9-octadecenamide, (9Z)-
9-octadecenamide, (Z)-
cis-9-octadecenoamide
cis-9,10-octadecenoamide
9-cis-oleamide
 oleamide Finawax-o finawax-O 珠子 beads
 

文章 Articles:

已发布 PubMed:预防性的 Preventive 效果 影响 Effects of a 发酵的 Fermented 乳业 D空气 airy Product 反对 against Alzheimer's 疾病 Disease and 鉴定 Identification of a 小说 Novel 油酰胺 Oleamide with 增强型 Enhanced 小胶质 Micro胶质细胞 glial 吞噬作用 Phagocytosis and 消炎 Anti-Inflammatory 活动 Activity.
已发布 PubMed: 细菌内生芽孢杆菌可可科 theobromae pat的代谢产物的表征。龙血树德拉科 通过lc-ms / ms。
已发布 PubMed:大麻素受体配体在小鼠强迫游泳试验中的抗抑郁样作用 Antidepressant-like effects of the cannabinoid receptor ligands in the forced swimming test in mice: 作用机理以及与胆碱能系统可能的相互作用。 Mechanism of action and possible interactions with cholinergic system.
已发布 PubMed:马来酸伊索拉定可调节 鼻上皮细胞中间隙连接的细胞间通讯依赖性上皮屏障。 Irsogladine Maleate Regulates Gap Junctional Intercellular Communication-Dependent Epithelial Barrier in Human Nasal Epithelial Cells.
已发布 PubMed:内源性大麻素在体外调节 血脑屏障通透性。 Endocannabinoids modulate human blood-brain barrier permeability in vitro.
已发布 PubMed:油酰胺对大鼠慢性轻度抑郁症模型抗抑郁作用的差异蛋白质组学分析。 Differential proteomic analysis of the anti-depressive effects of oleamide in a rat chronic mild stress model of depression.
已发布 PubMed:连接蛋白32的下调减弱了肝细胞的缺氧/复氧损伤。 Downregulation of Connexin 32 Attenuates Hypoxia/Reoxygenation Injury in Liver Cells.
已发布 PubMed:代谢组学研究表明,由于akr1b10而引起的醛糖还原酶活性在丙型肝炎 感染中被上调。 Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection.
已发布 PubMed:再谈小ry Prymnesium parvum revisited: 化感作用之间的relationship between allelopathy, 鱼鳞毒性 ichthyotoxicity, 和5种菌株的化学概况。 and chemical profiles in 5 strains.
已发布 PubMed:进入下丘脑外侧的2-花生四烯酰甘油可改善成年大鼠产后分离的睡眠。 2-Arachidonoylglycerol into the lateral hypothalamus improves reduced sleep in adult rats subjected to maternal separation.
已发布 PubMed:间隙连接细胞间通讯在奥沙利铂通过线粒体途径诱导的睾丸间质细胞凋亡中的作用 Role of gap junction intercellular communication in testicular leydig cell apoptosis induced by oxaliplatin via the mitochondrial pathway.
已发布 PubMed:水合环戊烷与物理和化学改性表面之间的粘附力相互作用。 Adhesion force interactions between cyclopentane hydrate and physically and chemically modified surfaces.
已发布 PubMed:膜从间充质干细胞转移至hl-1心脏细胞的证据。 Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.
已发布 PubMed:酰基二胺新系列作为潜在的抗菌剂和抗真菌剂的合成和生物学评估。 Synthesis and biological evaluation of a new series of N-acyldiamines as potential antibacterial and antifungal agents.
已发布 PubMed:v279f纯合基因型的携带 Carriage of the V279F homozygous genotype, 罕见的等位基因 a rare allele, 编码lp-pla2的基因中的内含子导致无代谢综合征的个体循环中间代谢物发生变化。 within the gene encoding Lp-PLA2 leads to changes in circulating intermediate metabolites in individuals without metabolic syndrome.
已发布 PubMed:代谢组学 Metabolomic 研究 study of 脂质 lipids in 血清 serum for 生物标志物 biomarker 发现 discovery in Alzheimer's 疾病 disease 使用 using direct 输液 infusion mass 光谱法 spectrometry.
已发布 PubMed:连接蛋白依赖性间隙连接增强涉及索拉非尼和全反式抗坏血酸对hcc生长抑制的协同作用。 Connexin-dependent gap junction enhancement is involved in the synergistic effect of sorafenib and all-trans retinoic acid on HCC growth inhibition.
已发布 PubMed:根分泌物刺激水浮萍根际脱氮的研究 Stimulation of nitrogen removal in the rhizosphere of aquatic duckweed by root exudate components.
已发布 PubMed:呼吸机致肺损伤的发病机理的代谢组学方法。 A Metabolomic Approach to the Pathogenesis of Ventilator-induced Lung Injury.
已发布 PubMed:异丙酚通过减弱七氟醚在体外对大鼠肝细胞的细胞毒性来抑制间隙连接。 Propofol inhibits gap junctions by attenuating sevoflurane-induced cytotoxicity against rat liver cells in vitro.
已发布 PubMed:金属加工液的接触过敏可追溯到妥尔油脂肪酸单乙醇酰胺。 Contact allergy from metalworking fluid traced to tall oil fatty acids monoethanolamide.
已发布 PubMed:甲酰胺及其合成类似物 Macamides and their synthetic analogs: 体外Faah抑制作用的评估。 evaluation of in vitro FAAH inhibition.
已发布 PubMed:乙型肝炎 相关肝细胞癌的 肝组织代谢谱研究。 Human liver tissue metabolic profiling research on hepatitis B virus-related hepatocellular carcinoma.
已发布 PubMed:异构间隙连接在顺铂细胞毒性中的作用 Role of heteromeric gap junctions in the cytotoxicity of cisplatin.
已发布 PubMed:黑素瘤间隙连接的调控及其对黑素-a / mart-1特异性cd8βt淋巴细胞出现的影响。 Regulation of gap junctions in melanoma and their impact on Melan-A/MART-1-specific CD8⁺ T lymphocyte emergence.
已发布 PubMed:脂肪酸酰胺水解酶反应性和共价抑制的非经验能量分析。 Nonempirical energetic analysis of reactivity and covalent inhibition of fatty acid amide hydrolase.
已发布 PubMed:脂肪酸酰胺水解酶重新激活的量子力学/分子力学建模将底物与不可逆共价抑制剂区分开来。 Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors.
已发布 PubMed:单核细胞增生性李斯特菌和肠炎歐洲海濱草生物膜对不同消毒剂的敏感性以及存活细胞的应激反应和毒力基因表达。 Lipid profiling for early diagnosis and progression of colorectal cancer using direct-infusion electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.
已发布 PubMed:通过溶剂挥发诱导微球的自组装纳米胶束结构聚集及其作为ph依赖药物释放系统的用途。 Fabrication of microspheres via solvent volatization induced aggregation of self-assembled nanomicellar structures and their use as a pH-dependent drug release system.
已发布 PubMed:新生大鼠星形胶质细胞中连接蛋白43的表达及间隙连接的功能调控 [Expression of connexin 43 and functional modulation of gap junction in neonatal rat astrocytes in vitro].
已发布 PubMed:β-d-葡萄糖苷可通过抑制erk并诱导pparγdna结合来防止晚期糖基化终产物(年龄)介导的糖尿病反应。 Beta-D-glucoside protects against advanced glycation end products (AGEs)-mediated diabetic responses by suppressing ERK and inducing PPAR gamma DNA binding.
已发布 PubMed:油酰胺可恢复成年雌性大鼠的睡眠。 Oleamide restores sleep in adult rats that were subjected to maternal separation.
已发布 PubMed:傅立叶变换离子回旋共振质谱法检测肺癌的性别特异性脂质代谢产物和诊断性生物标志物。 Probing gender-specific lipid metabolites and diagnostic biomarkers for lung cancer using Fourier transform ion cyclotron resonance mass spectrometry.
已发布 PubMed:大鼠和 类脂肪酸酰胺水解酶 Rat and human fatty acid amide hydrolases: 明显的相似之处和隐藏的差异。 overt similarities and hidden differences.
已发布 PubMed:脂多糖通过间隙连接功能的改变对nrk52e细胞增殖的影响。 Lipopolysaccharide effects on the proliferation of NRK52E cells via alternations in gap-junction function.
已发布 PubMed:油酰胺在体外激活过氧化物酶体增殖物激活的受体γ(pparγ)。 Oleamide activates peroxisome proliferator-activated receptor gamma (PPARγ) in vitro.
已发布 PubMed:与 类胃癌发病率相关的脂肪酸和脂肪酸酰胺代谢紊乱。 Metabolic disorders of fatty acids and fatty acid amides associated with human gastric cancer morbidity.
已发布 PubMed:内源性大麻素样介质的血管舒张作用增强 Enhanced vasorelaxant effects of the endocannabinoid-like mediator, oleamide, 在高血压。 in hypertension.
已发布 PubMed: 篇名[cx26 / cx32间隙连接通道对依托泊苷在海拉 Hela细胞中的抗肿瘤作用的影响]。
已发布 PubMed:骨中成骨细胞和骨细胞的自主细胞内ca(2+)振荡的原位成像。 In situ imaging of the autonomous intracellular Ca(2+) oscillations of osteoblasts and osteocytes in bone.
已发布 PubMed:巴拿马的抗疟疾天然产物药物发现。 Antimalarial natural products drug discovery in Panama.
已发布 PubMed:一级脂肪酸酰胺代谢 Primary fatty acid amide metabolism: n18tg2和scp细胞中脂肪酸和乙醇胺的转化 conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells.
已发布 PubMed:scar啶 Ascaridole, 茶树油的致敏成分 a sensitizing component of tea tree oil, 在两个系列的患者中分别以1%和5%的剂量测试了贴剂。 patch tested at 1% and 5% in two series of patients.
已发布 PubMed: 阿南酰胺 anandamide通过trpv1受体调节颈动脉窦橙花传入活动,从而增加对热的反应。
已发布 PubMed:连接蛋白抑制剂对大鼠膀胱出口梗阻所致逼尿肌过度活跃的治疗作用。 Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats.
已发布 PubMed:通过超高效液相色谱-质谱联用四极杆飞行时间质谱对醇和HBV引起的肝硬化之间的差异进行血清代谢组学研究。 A serum metabonomic study on the difference between alcohol- and HBV-induced liver cirrhosis by ultraperformance liquid chromatography coupled to mass spectrometry plus quadrupole time-of-flight mass spectrometry.
已发布 PubMed:苯甲酰氯预柱衍生化-高效液相色谱-飞行时间质谱联用测定 尿中的多胺 Connexin 32 and its derived homotypic gap junctional intercellular communication inhibit the migration and invasion of transfected HeLa cells via enhancement of intercellular adhesion.
已发布 PubMed:低浓度的阿仑膦酸盐可通过连接蛋白43激活增加成 瘤细胞系的局部浸润能力。 Low concentrations of alendronate increase the local invasive potential of osteoblastic sarcoma cell lines via connexin 43 activation.
已发布 PubMed:lc / ms的恶性疟原虫硫氧还蛋白还原酶配体结合方法鉴定番石榴中的油酰胺。 Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method.
已发布 PubMed:小ber碱可能通过调节缝隙连接来增强X射线 诱导的凋亡。 Berberine potentizes apoptosis induced by X-rays irradiation probably through modulation of gap junctions.
已发布 PubMed:脂肪酸酰胺水解酶(faah​​)的有效非共价抑制剂的发现和分子基础。 Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH).
已发布 PubMed:cc-dftb qm / mm方法在脂肪酸酰胺水解酶催化机理研究中的应用 Application of a SCC-DFTB QM/MM approach to the investigation of the catalytic mechanism of fatty acid amide hydrolase.
已发布 PubMed:内源性大麻素大麻酚与脂肪酸酰胺水解酶敲除小鼠的∆(9)-四氢大麻酚具有歧视性刺激作用。 The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice.
已发布 PubMed:内源性大麻素系统调节与食物摄入有关的情绪的效价。 The endocannabinoid system modulates the valence of the emotion associated to food ingestion.
已发布 PubMed:施用到伏隔核壳中的油酰胺可通过cb1和5-ht2c受体调节进食行为。 Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors.
已发布 PubMed:连接蛋白43主要参与生精上皮连接动力学和雄性育性。 Major involvement of connexin 43 in seminiferous epithelial junction dynamics and male fertility.
已发布 PubMed:从污水污泥快速热解产生的生物油中分离和鉴定有机氮物种。 Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge.
已发布 PubMed:通过和频产生振动光谱和反射吸收红外光谱研究了铝/油界面和铝/空气界面处油酰胺膜的结构。 The structure of oleamide films at the aluminum/oil interface and aluminum/air interface studied by Sum Frequency Generation (SFG) vibrational spectroscopy and Reflection Absorption Infrared Spectroscopy (RAIRS).
已发布 PubMed:油酰胺通过抑制bv2鼠小橙花胶质细胞中nf-kappab的活化来抑制脂多糖诱导的inos和cox-2表达。 Oleamide suppresses lipopolysaccharide-induced expression of iNOS and COX-2 through inhibition of NF-kappaB activation in BV2 murine microglial cells.
已发布 PubMed:合成大麻素作为草药产品中的设计药物的化学分析。 Chemical analysis of synthetic cannabinoids as designer drugs in herbal products.
已发布 PubMed:9(z)-十八烯酰胺的化学合成及其降血脂作用 Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: 一种在山芹菜籽精油中发现的生物活性剂。 a bioactive agent found in the essential oil of mountain celery seeds.
已发布 PubMed: 急性和亚慢性施用阿南酰胺 anandamide或油酰胺可增加大鼠的rem睡眠。
已发布 PubMed:细胞外atp和p2y2受体介导下颌下腺细胞机械刺激诱导的细胞间ca(2+)波 Extracellular ATP and P2Y2 receptors mediate intercellular Ca(2+) waves induced by mechanical stimulation in submandibular gland cells: 存储操作的ca(2+)进入的线粒体调控作用。 Role of mitochondrial regulation of store operated Ca(2+) entry.
已发布 PubMed:聚乙烯包装材料中脂肪酸酰胺的测定方法气相色谱/质谱法 Method for determination of fatty acid amides in polyethylene packaging materials--gas chromatography/mass spectrometry.
已发布 PubMed:使用gc-tofms和uplc-qtofms对 类大肠癌的血清代谢产物进行分析 Serum metabolite profiling of human colorectal cancer using GC-TOFMS and UPLC-QTOFMS.
已发布 PubMed:生物合成油酰胺。 Biosynthesis of oleamide.
已发布 PubMed:树突状细胞-t细胞界面的间隙连接是抗原依赖性t细胞活化的关键因素。 Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation.
已发布 PubMed:油酰胺诱导的大鼠肠系膜阻力动脉血管舒张的机制。 Mechanisms involved in oleamide-induced vasorelaxation in rat mesenteric resistance arteries.
已发布 PubMed:通过量子力学/分子力学(qm / mm)建模方法深入了解脂肪酸酰胺水解酶的机理和抑制作用。 Insights into the mechanism and inhibition of fatty acid amide hydrolase from quantum mechanics/molecular mechanics (QM/MM) modelling.
已发布 PubMed:间隙连接阻滞剂的性质及其行为 Properties of gap junction blockers and their behavioural, 认知和电生理作用 cognitive and electrophysiological effects: 动物和 类研究。 animal and human studies.
已发布 PubMed:从哺乳动物脂质-油酰胺直接在高度定向的热解石墨上一步一步形成直的纳米带。 One-step formation of straight nanostripes from a mammal lipid-oleamide directly on highly oriented pyrolytic graphite.
已发布 PubMed:酰胺对戊四唑诱发大鼠癫痫发作的作用 Effect of oleamide on pentylenetetrazole-induced seizures in rats.
已发布 PubMed:生物活性污染物从一次性实验室塑料制品中浸出。 Bioactive contaminants leach from disposable laboratory plasticware.
已发布 PubMed:缝隙连接在巨核细胞介导的成骨细胞增殖和分化中的作用。 The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation.
已发布 PubMed:油酰胺衍生物是典型的抗转移药物,可通过抑制连接蛋白26发挥作用。 Oleamide derivatives are prototypical anti-metastasis drugs that act by inhibiting Connexin 26.
已发布 PubMed:脂肪酸增强双氯芬酸皮肤渗透性。 Skin permeation enhancement of diclofenac by fatty acids.
已发布 PubMed:间隙连接在细胞因子诱导的明串球菌体内粘附于内皮的功能性作用。 Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo.
已发布 PubMed:生物合成 Biosynthesis, 脂肪酸酰胺的降解和药理重要性。 degradation and pharmacological importance of the fatty acid amides.
已发布 PubMed:cb1受体在调节睡眠中的作用。 The role of the CB1 receptor in the regulation of sleep.
已发布 PubMed:对 睑板和眼泪的脂质成分的影响 On the lipid composition of human meibum and tears: 非极性脂质的比较分析。 comparative analysis of nonpolar lipids.
已发布 PubMed:脂肪酸酰胺水解酶和单酰基甘油脂酶抑制剂的化学家族概述。 Overview of the chemical families of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors.
已发布 PubMed:大鼠主动脉受损原位内皮中的ca2 +信号传导。 Ca2+ signaling in injured in situ endothelium of rat aorta.
已发布 PubMed:脂肪酸酰胺水解酶 Fatty acid amide hydrolase: 从表征到治疗。 from characterization to therapeutics.
已发布 PubMed:角叉菜胶诱发的爪水肿模型中脂肪酸酰胺的评估 Evaluation of fatty acid amides in the carrageenan-induced paw edema model.
已发布 PubMed: 胫骨脂质 Lipids of human meibum: 质谱分析和结构阐明。 mass-spectrometric analysis and structural elucidation.
已发布 PubMed:通过定向进化工程化铜绿假单胞菌脂肪酶以增强酰胺酶活性 Engineering of Pseudomonas aeruginosa lipase by directed evolution for enhanced amidase activity: 丝氨酸水解酶水解酰胺的机理。 mechanistic implication for amide hydrolysis by serine hydrolases.
已发布 PubMed:油酰胺对雄性和雌性小鼠的橙花药理作用。 Neuropharmacological effects of oleamide in male and female mice.
已发布 PubMed:大鼠肉芽组织成熟涉及间隙连接通讯吗? Does rat granulation tissue maturation involve gap junction communications?
已发布 PubMed:干扰素-γ通过防止肠上皮细胞之间的间隙连接通讯来抑制肠道恢复。 Interferon-gamma inhibits intestinal restitution by preventing gap junction communication between enterocytes.
已发布 PubMed:在肝类器官的内皮细胞的间隙连接和窗孔之间的功能相互关系。 The functional interrelationship between gap junctions and fenestrae in endothelial cells of the liver organoid.
已发布 PubMed:细胞色素c体外合成油酰甘氨酸指向产生脂质信号分子的新途径。 In vitro synthesis of oleoylglycine by cytochrome c points to a novel pathway for the production of lipid signaling molecules.
已发布 PubMed:油酸酰胺对群居和社会隔离小鼠的抗焦虑作用。 Anxiolytic-like effects of oleamide in group-housed and socially isolated mice.
已发布 PubMed:山茶油及其馏分有效抑制小鼠黑素瘤bl6细胞的自发转移。 Camellia oil and its distillate fractions effectively inhibit the spontaneous metastasis of mouse melanoma BL6 cells.
已发布 PubMed:大鼠肾脏中油酰胺的合成活性 Oleamide synthesizing activity from rat kidney: 鉴定为细胞色素c。 identification as cytochrome c.
已发布 PubMed:油酰胺 Oleamide: 心血管系统中的脂肪酸酰胺信号分子? a fatty acid amide signaling molecule in the cardiovascular system?
已发布 PubMed:油酰胺衍生物通过抑制连接蛋白26抑制自发转移。 Oleamide derivatives suppress the spontaneous metastasis by inhibiting connexin 26.
已发布 PubMed:强效和选择性的基于α-酮杂环的安南酰胺和油酰胺分解代谢酶抑制剂 Potent and selective alpha-ketoheterocycle-based inhibitors of the anandamide and oleamide catabolizing enzyme, 脂肪酸酰胺水解酶。 fatty acid amide hydrolase.
已发布 PubMed: 睑板腺分泌物中脂肪酸和脂肪酸酰胺的鉴定 Identification of fatty acids and fatty acid amides in human meibomian gland secretions.
已发布 PubMed:通过qm / mm模拟阐明了脂肪酸酰胺水解酶及其lys142ala变体的水解机理。 Elucidation of hydrolysis mechanisms for fatty acid amide hydrolase and its Lys142Ala variant via QM/MM simulations.
已发布 PubMed:胶态二氧化铀纳米晶体的合成。 Synthesis of colloidal uranium-dioxide nanocrystals.
已发布 PubMed:气相色谱法测定聚乙烯薄膜中增滑剂的Comparison of three gas chromatography methods for the determination of slip agents in polyethylene films.
已发布 PubMed:抑郁症患者的脂肪酸和睡眠。 Fatty acids and sleep in depressed inpatients.
已发布 PubMed:进样器内部通过程序升温汽化(ptv)进样从食用油中进行热脱附。 Injector-internal thermal desorption from edible oils performed by programmed temperature vaporizing (PTV) injection.
已发布 PubMed:心脏线粒体连接蛋白43调节细胞凋亡。 Cardiac mitochondrial connexin 43 regulates apoptosis.
已发布 PubMed:分泌蛋白作为马中潜在的化学信息载体。 Secretory proteins as potential semiochemical carriers in the horse.
已发布 PubMed:体内证据表明,正油酰甘氨酸作用与其转化为油酰胺无关。 In vivo evidence that N-oleoylglycine acts independently of its conversion to oleamide.
已发布 PubMed:弗雷泽河谷下部pm2.5气溶胶中含氮有机化合物的化学特征和来源。 Chemical characteristics and origins of nitrogen-containing organic compounds in PM2.5 aerosols in the Lower Fraser Valley.
已发布 PubMed:间隙连接通讯在c57b1小鼠转移性b16黑素瘤中的作用 [The role of gap junction communication in metastatic B16 melanoma in C57BL mice].
已发布 PubMed:在胎盘哺乳动物中具有可变分布的第二种脂肪酸酰胺水解酶。 A second fatty acid amide hydrolase with variable distribution among placental mammals.
已发布 PubMed:连接蛋白26的表达可防止 气道上皮细胞系calu-3中的na + / k + -atpase抑制剂哇巴因下调紧密连接的屏障和栅栏功能 Connexin 26 expression prevents down-regulation of barrier and fence functions of tight junctions by Na+/K+-ATPase inhibitor ouabain in human airway epithelial cell line Calu-3.
已发布 PubMed: 沙漠刺五加(血吸虫 Schistocerca 格雷格雷里亚 gregaria)化学传感蛋白的溶液结构
已发布 PubMed:一种潜在的新机制,涉及连接蛋白43间隙连接,可通过甲状腺激素控制睾丸细胞的增殖。 A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones.
已发布 PubMed:使用基于微粒体的荧光测定法进行高通量筛选,以发现脂肪酸酰胺水解酶的抑制剂。 High-throughput screening for the discovery of inhibitors of fatty acid amide hydrolase using a microsome-based fluorescent assay.
已发布 PubMed:拟南芥酰胺酶1的亚细胞定位和组织特异性表达 Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana.
已发布 PubMed:加压流体萃取和气相色谱法测定聚乙烯薄膜中的油酰胺和芥酸酰胺。 Determination of oleamide and erucamide in polyethylene films by pressurised fluid extraction and gas chromatography.
已发布 PubMed:初级感觉橙花元中的Olvanil瞬时受体电位香草样1型刺激下调电压激活的ca2 +通道的信号传导机制 Signaling mechanisms of down-regulation of voltage-activated Ca2+ channels by transient receptor potential vanilloid type 1 stimulation with olvanil in primary sensory neurons.
已发布 PubMed:油酰胺增强p53突变细胞的放射增敏作用。 Enhanced radiosensitization of p53 mutant cells by oleamide.
已发布 PubMed:间隙连接可能参与脑和肺内皮细胞紧密连接的屏障功能 Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells.
已发布 PubMed:间隙连接通讯对I型胶原和纤连蛋白成纤维细胞合成的影响。 Gap junction communications influence upon fibroblast synthesis of Type I collagen and fibronectin.
已发布 PubMed:油酰胺在大鼠小肠系膜动脉中的血管舒张作用表明对新型大麻素受体有作用。 Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
已发布 PubMed: 脂肪酸酰胺水解酶(-/-)小鼠对工作记忆水迷宫任务中的阿南酰胺 anandamide或油酰胺的破坏作用表现出更高的敏感性。
已发布 PubMed:阐明了来自蒙特卡洛模拟的有效α-酮杂环衍生物对脂肪酸酰胺水解酶的抑制作用。 Elucidation of fatty acid amide hydrolase inhibition by potent alpha-ketoheterocycle derivatives from Monte Carlo simulations.
已发布 PubMed:血红素抑制纤维蛋白凝胶基质中vegf诱导的血管生成。 Sample preparation and gas chromatography of primary fatty acid amides.
已发布 PubMed:脂肪酸酰胺水解酶在体内可控制小鼠肠动力。 Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
已发布 PubMed:脂肪酸酰胺水解酶(faah​​)中油酰胺水解qm / mm模型揭示了亲核试剂活化的新机制。 QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation.
已发布 PubMed:重点研究水解内源性大麻素作为新药靶点的三种关键酶。 Focus on the three key enzymes hydrolysing endocannabinoids as new drug targets.
已发布 PubMed:靶向脂质组学 Targeted lipidomics: 脂肪酸酰胺和疼痛调节。 fatty acid amides and pain modulation.
已发布 PubMed:脂肪酸酰胺水解酶的结构和功能 Structure and function of fatty acid amide hydrolase.
已发布 PubMed:在大鼠强迫游泳试验中,大麻素cb1受体活性的药理作用增强引起了抗抑郁样反应。 Pharmacological enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the rat forced swim test.
已发布 PubMed:适用于高通量筛选的脂肪酸酰胺水解酶的分光光度测定法。 A spectrophotometric assay for fatty acid amide hydrolase suitable for high-throughput screening.
已发布 PubMed:发现有力 Discovery of a potent, 可选择的 selective, 一类有效的镇痛药,即脂肪酸酰胺水解酶的可逆性α-酮杂环化合物的可逆抑制剂。 and efficacious class of reversible alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase effective as analgesics.
已发布 PubMed:椰油酰胺丙基甜菜碱引起的过敏性接触性皮炎 Allergic contact dermatitis from cocamidopropyl betaine, 椰油酰胺 cocamidoamine, 3-(二甲基氨基)丙胺 3-(dimethylamino)propylamine, 和油酰胺基丙基二甲基胺 and oleamidopropyl dimethylamine: 共同反应还是交叉反应? co-reactions or cross-reactions?
已发布 PubMed:脂肪酸酰胺水解酶的杂环亚砜和砜抑制剂。 Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase.
已发布 PubMed:脑室上皮中的脂肪酸酰胺水解酶 Fatty acid amide hydrolase in brain ventricular epithelium: 在小鼠和大鼠中的互斥表达模式。 mutually exclusive patterns of expression in mouse and rat.
已发布 PubMed:表征缺乏脂肪酸酰胺水解酶的小鼠的睡眠-觉醒模式。 Characterization of the sleep-wake patterns in mice lacking fatty acid amide hydrolase.
已发布 PubMed:小鼠橙花母细胞瘤n18tg2细胞中油酸衍生的代谢产物。 Oleic acid derived metabolites in mouse neuroblastoma N18TG2 cells.
已发布 PubMed:促进镇痛的脂肪酸酰胺水解酶可逆抑制剂 Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: 有力地结合了选择性和选择性的证据。 evidence for an unprecedented combination of potency and selectivity.
已发布 PubMed:肥大细胞通过间隙连接的细胞间通讯促进成纤维细胞聚集的胶原晶格收缩。 Mast cells promote fibroblast populated collagen lattice contraction through gap junction intercellular communication.
已发布 PubMed:油酰胺的衍生物有效抑制小鼠黑素瘤b16细胞的自发转移。 A derivative of oleamide potently inhibits the spontaneous metastasis of mouse melanoma BL6 cells.
已发布 PubMed:油酰胺和阿南酰胺对食物摄入和大鼠性行为的影响。 Oleamide and anandamide effects on food intake and sexual behavior of rats.
已发布 PubMed:胚芽发生过程中基于cx43的间隙连接的功能表征。 Functional characterization of Cx43 based gap junctions during spermatogenesis.
已发布 PubMed:睡眠脂质油酰胺可能代表内源性抗惊厥药 The sleep lipid oleamide may represent an endogenous anticonvulsant: 在4-氨基吡啶大鼠脑切片模型中进行的体外比较研究。 an in vitro comparative study in the 4-aminopyridine rat brain-slice model.
已发布 PubMed:诱导睡眠的脂质油酰胺和大麻素对大鼠海马ca1橙花元中长期增强的诱导的不同影响。 Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro.
已发布 PubMed:油酰胺是大鼠和 cb1大麻素受体的选择性内源性激动剂。 Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors.
已发布 PubMed:油酰胺 Oleamide: 内源性大麻素家族的成员? a member of the endocannabinoid family?
已发布 PubMed:诱导睡眠的脑脂质顺式油酰胺(coa)不会在体外调节海马ca1锥体橙花元中的血清素能传递。 The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro.
已发布 PubMed:血清素能系统可能参与了油酰胺对大鼠的睡眠诱导作用。 The serotonergic system may be involved in the sleep-inducing action of oleamide in rats.
已发布 PubMed:抑制脂肪酸酰胺水解酶 Inhibition of fatty acid amidohydrolase, 负责内源性大麻素异戊酰胺代谢的酶 the enzyme responsible for the metabolism of the endocannabinoid anandamide, 由花生四烯酰血清素的类似物。 by analogues of arachidonoyl-serotonin.
已发布 PubMed:油酰胺的选择性作用 Selective effect of oleamide, 内源性诱导睡眠的脂酰胺 an endogenous sleep-inducing lipid amide, 对戊四氮诱发的小鼠癫痫发作。 on pentylenetetrazole-induced seizures in mice.
已发布 PubMed:油酰胺对胆碱乙酰转移酶和认知活动的影响 Effects of oleamide on choline acetyltransferase and cognitive activities.
已发布 PubMed:用于确定脂肪酸酰胺水解酶活性的高通量兼容测定。 A high-throughput-compatible assay for determining the activity of fatty acid amide hydrolase.
已发布 PubMed:脂肪酸酰胺水解酶丝氨酸-丝氨酸-赖氨酸催化三联体的残基催化作用的独特证据。 Evidence for distinct roles in catalysis for residues of the serine-serine-lysine catalytic triad of fatty acid amide hydrolase.
已发布 PubMed:非快速眼动睡眠的生化调节。 Biochemical regulation of non-rapid-eye-movement sleep.
已发布 PubMed: 缝连接抑制剂抑制微隔离鼠破骨细胞中连接蛋白43 姆纳 mRNA的表达及体外骨吸收调节躯干。
已发布 PubMed:通过直接脂肪酶催化的氨酰胺化反应在经济上连续形成酰胺。 Economically pertinent continuous amide formation by direct lipase-catalyzed amidation with ammonia.
已发布 PubMed:芥酸酰胺作为水平衡调节剂 Erucamide as a modulator of water balance: 脂肪酸酰胺的新功能 new function of a fatty acid amide.
已发布 PubMed:在f344 / n大鼠和b6c3f1小鼠中的油酸二乙醇胺缩合物(CAS号93-83-4)的ntp毒理学和致癌作用研究(皮肤研究)。 NTP Toxicology and Carcinogenesis Studies of Oleic Acid Diethanolamine Condensate (CAS No. 93-83-4) in F344/N Rats and B6C3F1 Mice (Dermal Studies).
已发布 PubMed:5-ht7受体敲除小鼠对5-羟色胺没有低温反应。 No hypothermic response to serotonin in 5-HT7 receptor knockout mice.
已发布 PubMed:内源性大麻素及相关脂肪酸衍生物在疼痛调节中的作用。 Endocannabinoids and related fatty acid derivatives in pain modulation.
已发布 PubMed:信号脂质类脂肪酸酰胺类的酶促失活。 The enzymatic inactivation of the fatty acid amide class of signaling lipids.
已发布 PubMed:亚油酰胺可阻断erg电流 Block of erg current by linoleoylamide, 睡眠诱导剂 a sleep-inducing agent, 在垂体gh3细胞中。 in pituitary GH3 cells.
已发布 PubMed:中观膜蛋白结晶 Membrane protein crystallization in meso: 荜澄茄/山苍子相的脂质类型定制。 lipid type-tailoring of the cubic phase.
已发布 PubMed:间隙连接介导的卵裂球阵营信号在体细胞中诱导oct-3 / 4表达。 Induction of Oct-3/4 expression in somatic cells by gap junction-mediated cAMP signaling from blastomeres.
已发布 PubMed:内源性大麻素水解酶。 Endocannabinoid hydrolases.
已发布 PubMed:腰椎运动核中染料偶联的模式 Patterns of dye coupling in lumbar motor nuclei of the rat.
已发布 PubMed:共轭亚油酸(cla)抑制caco-2结肠癌细胞的生长 Conjugated linoleic acid (CLA) inhibits growth of Caco-2 colon cancer cells: 油酰胺可能介导。 possible mediation by oleamide.
已发布 PubMed:油酰胺可减轻培养的大鼠小脑颗粒橙花元的凋亡死亡。 Oleamide attenuates apoptotic death in cultured rat cerebellar granule neurons.
已发布 PubMed:大麻素在睡眠期间呼吸稳定性中的功能性作用。 Functional role for cannabinoids in respiratory stability during sleep.
已发布 PubMed:脂肪酸酰胺的药理活性受到调节 Pharmacological activity of fatty acid amides is regulated, 但没有调解 but not mediated, 通过体内的脂肪酸酰胺水解酶。 by fatty acid amide hydrolase in vivo.
已发布 PubMed:间隙连接细胞间通讯在癌细胞中传播细胞死亡。 Gap junction intercellular communication propagates cell death in cancerous cells.
已发布 PubMed:睡眠激素油酰胺可在体外调节哺乳动物中枢橙花系统的抑制性离子受体。 The sleep hormone oleamide modulates inhibitory ionotropic receptors in mammalian CNS in vitro.
已发布 PubMed:脂肪酸酰胺水解酶 Fatty acid amide hydrolase, 一种具有许多生物活性底物的酶。可能的治疗意义。 an enzyme with many bioactive substrates. Possible therapeutic implications.
已发布 PubMed:相对于橙花病靶标酯酶和乙酰胆碱酯酶的脂肪酸酰胺水解酶的选择性抑制剂 Selective inhibitors of fatty acid amide hydrolase relative to neuropathy target esterase and acetylcholinesterase: 毒理学意义。 toxicological implications.
已发布 PubMed:亚油酰胺的体外生物加氢及其对绵羊十二指肠内容物中亚油酸浓度的影响 The biohydrogenation of linoleamide in vitro and its effects on linoleic acid concentration in duodenal contents of sheep.
已发布 PubMed: gaba(a)受体beta beta 3亚基的删除消除了油酰胺在小鼠中的催眠作用。
已发布 PubMed:酰胺对 膀胱癌细胞ca(2+)信号传导的影响 Effect of oleamide on Ca(2+) signaling in human bladder cancer cells.
已发布 PubMed:表征 Characterization of the 5'-sequence of the 老鼠 mouse 脂肪酸酰胺水解酶。 fatty acid amide hydrolase.
已发布 PubMed:油酰胺调节大鼠的记忆。 Oleamide modulates memory in rats.
已发布 PubMed:脂肪酸酰胺的催眠作用 The hypnotic actions of the fatty acid amide, 油酰胺。 oleamide.
已发布 PubMed:油酰胺对睡眠的影响及其与血压的关系 Effect of oleamide on sleep and its relationship to blood pressure, 体温 body temperature, 和运动能力在大鼠中。 and locomotor activity in rats.
已发布 PubMed:催化抗体在活细胞中产生间隙连接通讯的荧光示踪剂。 A catalytic antibody produces fluorescent tracers of gap junction communication in living cells.
已发布 PubMed:脂肪酸酰胺水解酶 Fatty acid amide hydrolase: 生物化学 biochemistry, 药理 pharmacology, 酶水解阿南酰胺的治疗方法和治疗可能性 and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-花生四烯酰甘油 2-arachidonoylglycerol, 棕榈酰乙醇酰胺 palmitoylethanolamide, 和油酰胺。 and oleamide.
已发布 PubMed:油酰胺与多种橙花递质系统相互作用的行为证据。 Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems.
已发布 PubMed:缝隙连接调节成纤维细胞生长因子2对培养的中脑多巴胺能橙花元的存活促进作用。 Gap junctions modulate survival-promoting effects of fibroblast growth factor-2 on cultured midbrain dopaminergic neurons.
已发布 PubMed:脂肪酸酰胺水解酶的α-酮杂环抑制剂 alpha-Keto heterocycle inhibitors of fatty acid amide hydrolase: 羰基修饰和α-取代。 carbonyl group modification and alpha-substitution.
已发布 PubMed:直接甲基化程序,用于在饲料和消化液样品中将脂肪酰胺转化为脂肪酸甲酯。 Direct methylation procedure for converting fatty amides to fatty acid methyl esters in feed and digesta samples.
已发布 PubMed:脂肪酸酰胺水解酶的酰基链选择性的表征和操作。 Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase.
已发布 PubMed:橙花毒性有机磷农药可抑制脂肪酸酰胺水解酶。 Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides.
已发布 PubMed:调节橙花调节性脂肪酸酰胺的生物合成和失活的蛋白质。 Proteins regulating the biosynthesis and inactivation of neuromodulatory fatty acid amides.
已发布 PubMed:间隙连接通讯是培养中成骨细胞成熟过程所必需的。 Gap-junctional communication is required for the maturation process of osteoblastic cells in culture.
已发布 PubMed:间隙连接通讯的抑制作用诱导成骨细胞在体外向分化成脂肪细胞的表型。 Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro.
已发布 PubMed:诱导睡眠的脂质油酰胺与哺乳动物脑中电压门控钠通道的类似麻醉剂的相互作用。 Anesthetic-like interaction of the sleep-inducing lipid oleamide with voltage-gated sodium channels in mammalian brain.
已发布 PubMed:脂肪酸酰胺水解酶底物特异性。 Fatty acid amide hydrolase substrate specificity.
已发布 PubMed:内源性大麻素和脂肪酸酰胺在癌症中的作用 Endocannabinoids and fatty acid amides in cancer, 炎症和相关疾病。 inflammation and related disorders.
已发布 PubMed:脂肪酸酰胺水解酶(faah​​)。 The fatty acid amide hydrolase (FAAH).
已发布 PubMed:给牛饲喂油酰胺的地点和时间,取决于采食量和小酸模/羊酸模/红酸模脂肪酸浓度。 Site of administration and duration of feeding oleamide to cattle on feed intake and ruminal fatty acid concentrations.
已发布 PubMed:连接蛋白模拟肽可逆地通过气道细胞中的间隙连接抑制ca(2+)信号传导。 Connexin mimetic peptides reversibly inhibit Ca(2+) signaling through gap junctions in airway cells.
已发布 PubMed: 早期迁徙的大鼠橙花细胞 细胞 cells细胞表达功能性间隙连接 : 有证据表明橙花c细胞的存活需要间隙连接功能 evidence that neural crest cell survival requires gap junction function.
已发布 PubMed:齿状回中非突触场爆发的ph敏感性。 pH Sensitivity of non-synaptic field bursts in the dentate gyrus.
已发布 PubMed:脂肪酸酰胺水解酶的超强抑制剂 Exceptionally potent inhibitors of fatty acid amide hydrolase: 该酶负责降解内源性油酰胺和阿南酰胺。 the enzyme responsible for degradation of endogenous oleamide and anandamide.
已发布 PubMed:阿南酰胺酰胺水解酶(脂肪酸酰胺水解酶)。 Anandamide amidohydrolase (fatty acid amide hydrolase).
已发布 PubMed:阐明了酰胺酶签名家族中保守残基的催化作用。 Clarifying the catalytic roles of conserved residues in the amidase signature family.
已发布 PubMed:将油酰胺喂给哺乳期的奶牛。 2.对养分消化率的影响 Feeding oleamide to lactating Jersey cows. 2. Effects on nutrient digestibility, 血浆脂肪酸 plasma fatty acids, 和激素。 and hormones.
已发布 PubMed:向泌乳的泽西母牛饲喂油酰胺1.对泌乳性能和牛奶脂肪酸组成的影响。 Feeding oleamide to lactating Jersey cows 1. Effects on lactation performance and milk fatty acid composition.
已发布 PubMed:大鼠脉络丛中脂肪酸酰胺水解酶的表达 Fatty acid amide hydrolase expression in rat choroid plexus: 可能在调节油酰胺的睡眠诱导作用中发挥作用。 possible role in regulation of the sleep-inducing action of oleamide.
已发布 PubMed:间隙连接半通道的生理作用。细胞外钙依赖性等渗体积调节。 Physiological role of gap-junctional hemichannels. Extracellular calcium-dependent isosmotic volume regulation.
已发布 PubMed:油酰胺在体外对gaba(a)受体和电压门控na(+)通道的立体选择性调节作用 Stereoselective modulatory actions of oleamide on GABA(A) receptors and voltage-gated Na(+) channels in vitro: 用于中枢橙花系统抑制药物位点的推定内源性配体。 a putative endogenous ligand for depressant drug sites in CNS.
已发布 PubMed:n(18)tg(2)细胞中肽基甘氨酸α-酰胺化单加氧酶的诱导 Induction of peptidylglycine alpha-amidating monooxygenase in N(18)TG(2) cells: 研究油酰胺生物合成的模型。 a model for studying oleamide biosynthesis.
已发布 PubMed:油酰胺介导的睡眠诱导不依赖于膜稳态粘度的扰动。 Oleamide-mediated sleep induction does not depend on perturbation of membrane homeoviscosity.
已发布 PubMed:油酰胺的催眠作用被大麻素受体拮抗剂阻断。 The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist.
已发布 PubMed:油酸酰胺对5-羟基色胺7受体结合特性的变构调节。 Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors.
已发布 PubMed:鉴定脂肪酸酰胺水解酶催化的两个丝氨酸残基。 Identification of two serine residues involved in catalysis by fatty acid amide hydrolase.
已发布 PubMed:猪脑中的花生四烯酸酰胺水解酶 Anandamide amidohydrolase of porcine brain: cdna克隆 cDNA cloning, 功能表达和定点诱变(1)。 functional expression and site-directed mutagenesis(1).
已发布 PubMed:酰胺对小鼠的镇静和催眠作用的研究。 Studies on the sedative and hypnotic effects of oleamide in mice.
已发布 PubMed:棕榈酰乙醇酰胺和油酰胺之谜 The palmitoylethanolamide and oleamide enigmas : 这两种脂肪酸酰胺是大麻模拟物吗? are these two fatty acid amides cannabimimetic?
已发布 PubMed:脂肪酸酰胺水解酶的化学和诱变研究 Chemical and mutagenic investigations of fatty acid amide hydrolase: 具有明显催化特性的丝氨酸水解酶家族的证据。 evidence for a family of serine hydrolases with distinct catalytic properties.
已发布 PubMed:饲喂0至5%油酰胺的荷斯坦奶牛的泌乳性能和脂肪酸组成。 Lactation performance and fatty acid composition of milk from Holstein cows fed 0 to 5% oleamide.
已发布 PubMed:内源性脂质油酰胺可激活小鼠丘脑和下丘脑的5-羟色胺5-ht7橙花元。 The endogenous lipid oleamide activates serotonin 5-HT7 neurons in mouse thalamus and hypothalamus.
已发布 PubMed:气相色谱-质谱分析法,用于定量测定生物流体中的油酰胺。 A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids.
已发布 PubMed:油酰胺催眠特性的表征。 Characterization of the hypnotic properties of oleamide.
已发布 PubMed:油酰胺对大鼠体内5-ht2受体介导行为的修饰作用以及大麻素受体的作用。 Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors.
已发布 PubMed:心脏间隙连接通道的电子低温晶体学。 Electron cryo-crystallography of a recombinant cardiac gap junction channel.
已发布 PubMed:油酰胺 Oleamide: 内源性诱导睡眠的脂质和新型生物信号分子的原型成员。 an endogenous sleep-inducing lipid and prototypical member of a new class of biological signaling molecules.
已发布 PubMed:脂肪酸酰胺水解酶的三氟甲基酮抑制剂 Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: 有助于抑制的结构和构象特征的探针。 a probe of structural and conformational features contributing to inhibition.
已发布 PubMed:油酰胺诱导的5-羟色胺受体介导的信号传导调节。 Oleamide-induced modulation of 5-hydroxytryptamine receptor-mediated signaling.
已发布 PubMed: 香草醛激动剂奥尔万尼 olvanil抑制阿南酰胺 anandamide转运。
已发布 PubMed: 保留 类和小鼠脂肪酸酰胺水解酶基因的染色体位置和基因组结构,并评估clasper clasper作为候选橙花系统突变。
已发布 PubMed:间隙连接介导的细胞间通讯调节小鼠橙花c迁移。 Gap junction-mediated cell-cell communication modulates mouse neural crest migration.
已发布 PubMed:型和跨膜结构域缺失的脂肪酸酰胺水解酶的比较表征 Comparative characterization of a wild type and transmembrane domain-deleted fatty acid amide hydrolase: 跨膜结构域作为寡聚化位点的鉴定。 identification of the transmembrane domain as a site for oligomerization.
已发布 PubMed:花生四烯酸羟色胺和其他新型的脂肪酸酰胺水解酶抑制剂。 Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase.
已发布 PubMed: 乳腺癌和大鼠嗜铬细胞瘤细胞中生物活性脂肪酸酰胺的生物合成和降解-对细胞增殖和分化的影响 Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation.
已发布 PubMed:油酰胺增强了对苯二氮卓敏感的γ-氨基丁酸受体的活性,但不会改变最低的肺泡麻醉剂浓度。 Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration.
已发布 PubMed:生物活性脂质油酰胺抑制间隙连接通讯的化学要求。 Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.
已发布 PubMed:生物活性脂质油酰胺对5-ht2a和5-ht1a血清素受体增强的结构要求。 Structural requirements for 5-HT2A and 5-HT1A serotonin receptor potentiation by the biologically active lipid oleamide.
已发布 PubMed:喂固体油酰胺或低芥酸菜子油的荷斯坦奶牛的牛奶中脂肪酸组成。 Fatty acid composition of milk from Holstein cows fed oleamide or canola oil.
已发布 PubMed:脂肪酸生物活性酰胺。 Bioactive amides of fatty acids.
已发布 PubMed:花生四烯酸酰胺水解酶与2-花生四烯酰甘油反应 Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, 另一个大麻素受体配体。 another cannabinoid receptor ligand.
已发布 PubMed:油酸酰胺对5-羟色胺受体介导的信号转导的独特变构调节。 Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.
已发布 PubMed:诱导睡眠的脂质油酰胺使橙花胶质细胞中的缝隙连接通讯和钙波传输反卷积。 The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells.
已发布 PubMed:脂肪酸酰胺水解酶 Fatty acid amide hydrolase, 花生四烯酸和油酰胺的降解酶 the degradative enzyme for anandamide and oleamide, 在大鼠中枢橙花系统内的橙花元中具有选择性分布。 has selective distribution in neurons within the rat central nervous system.
已发布 PubMed:睡眠诱导因子油酰胺是由小鼠橙花母细胞瘤细胞产生的。 The sleep inducing factor oleamide is produced by mouse neuroblastoma cells.
已发布 PubMed: 重组大鼠脂肪酸酰胺水解酶证明了可逆性水解和阿南酰胺 anandamide的合成。
已发布 PubMed: 和小鼠脂肪酸酰胺水解酶的分子表征。 Molecular characterization of human and mouse fatty acid amide hydrolases.
已发布 PubMed:降解橙花调节性脂肪酸酰胺的酶的分子特征。 Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides.
已发布 PubMed:酶法合成油酰胺(顺式9 Enzymatic synthesis of oleamide (cis-9, 10-十八碳酰胺) 10-octadecenoamide), 内源性睡眠诱导脂质 an endogenous sleep-inducing lipid, 通过大鼠脑微粒体。 by rat brain microsomes.
已发布 PubMed:模拟胃肠道液中油酰胺的水解研究。 Hydrolysis studies on oleamide in simulated gastrointestinal fluids.
已发布 PubMed:对油酰胺基丙基二甲基胺及相关物质过敏。 Contact allergy to oleamidopropyl dimethylamine and related substances.
已发布 PubMed:酰胺基丙基二甲胺的补丁测试稀释液。 The patch test dilution of oleamidopropyl dimethylamine.
已发布 PubMed:小鼠肝中酸性醇脱氢酶的变构作用及其在醇代谢中的作用 [Allosterism of acidic alcohol dehydrogenase (class III ADH) of mouse liver and its role in alcohol metabolism].
已发布 PubMed:液相色谱在线放射化学检测技术在新型镇痛药代谢研究中的应用 Application of liquid chromatography with on-line radiochemical detection to metabolism studies on a novel class of analgesics.
已发布 PubMed:油酰胺基丙基二甲基胺。 Oleamidopropyl dimethylamine.
已发布 PubMed:变色法测定药物制剂中的季铵表面活性剂 Determination of quaternary ammonium surfactants in pharmaceutical formulations by the hypochromic effect.
已发布 PubMed:阳离子乳化剂油酰胺基丙基二甲基胺的交叉反应模式。 Cross-reaction pattern of the cationic emulsifier oleamidopropyl dimethylamine.
已发布 PubMed:ne-19550 NE-19550: 一本小说 a novel, 口服抗炎镇痛药。 orally active anti-inflammatory analgesic.
已发布 PubMed:对油酰胺基丙基二甲胺过敏。 Contact allergy to oleamidopropyl dimethylamine.
已发布 PubMed:长链脂肪酸抑制糜酶活性。 Inhibition of chymase activity by long chain fatty acids.
 
笔记 Notes:
塑料添加剂会引起接触性荨麻疹;睡眠诱发因素。从食品包装中迁移出来的脱模剂 plastic additive; can cause contact urticaria; a sleep inducing factor. Release agent migrating from food packaging 油酰胺是脂肪酸油酸酰胺。它是一种内源性物质 Oleamide is an amide of the fatty acid oleic acid. It is an endogenous substance: 它自然存在于动物体内。它在睡眠剥夺过程中会积聚在脑脊液中,并诱发动物睡眠。正在研究它作为治疗情绪和睡眠障碍的潜在药物 it occurs naturally in the body of animals. It accumulates in the cerebrospinal fluid during sleep deprivation and induces sleep in animals. It is being studied as a potential medical treatment for mood and sleep disorders, and 大麻素调节 大麻素 cannabinoid-规范的 regulated 萧条 depression.; The 机制 mechanism of action of oleamide's 睡觉 sleep 诱导 inducing 效果 影响 effects is an area of current 研究 research. it It is 可能的 likely that oleamide 互动 inter行为 acts with multiple 橙花递质 neurotransmitter 系统 systems. 油酰胺 Oleamide is 结构上 结构的 structurally 有关 related to the 内生的 endogenous 大麻素 cannabinoid 阿南酰胺 anandamide, 并具有与cb1受体完全激动剂结合的能力。 and has the ability to bind to the CB1 receptor as a full agonist.
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