melanin

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    8049-97-6黑素95% 8049-97-6 Melanin 95%
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    gk4761黑素 GK4761 Melanin
CAS号 CAS Number: 8049-97-6Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:232-473-6
MDL :mfcd00131581 MFCD00131581
XlogP3-AA:-1.20(est) -1.20 (est)
分子量 Molecular Weight:318.28850000
式 Formula:c18 h10 n2 o4 C18 H10 N2 O4
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:cosmetic ingredient for skin protecting
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
溶于 Soluble in:
 水 water, 3.397e + 005 mg / l @ 25°c(est) 3.397e+005 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: 皮肤保护剂 skin protecting agents
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
黑素95% Melanin 95%
Glentham Life Sciences
Melanin
脂类化学品 Lipo Chemicals
脂 Lipo® Melanin 10% 解 Solution
气味 Odor: 特性 characteristic
采用 Use: 脂 Lipo® Melanin is a 综合地 synthetically produced 当量 equivalent to 自然 natural melanin, 在头发和皮肤中发现的色素。 the pigment found in hair and skin.
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
黑素≥99% Melanin ≥99%
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
黑素合成 Melanin Synthetic
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: cosmetic ingredient for skin protecting
黑素使用水平的建议 Recommendation for melanin usage levels up to:
 不用于香水。 not for fragrance use.
 
黑素风味使用水平的推荐值 Recommendation for melanin flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
欧洲食品安全局(efsa EFSA)参考 :

科学的 Scientific 意见 opinion on the 安全 safety and 功效 efficacy of 酪氨酸 L-tyrosine for all animal species
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :6325610
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:数据 Data
德国wgk WGK Germany:1
chemidplus Chemidplus:0008049976
 
参考资料 References:
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):6325610
pubchem(sid) Pubchem (sid):135312318
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
KEGG (GenomeNet):C05606
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB04068
食物 FooDB:FDB023298
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and 核心 core components note
没找到 None Found
 
潜在用途 Potential Uses:
 生物添加剂 biological additives
 
存在(自然 Occurrence (nature, food, 其他) other):note
 天然产物 found in nature
 
同义词 Synonyms:
 lipo melanin 10% solution
 脂盾 liposhield 混合动力车 HEV melanin
 
 
笔记 Notes:
酪氨酸衍生物的不溶性聚合物存在于皮肤中并导致皮肤变黑(皮肤色素沉着) insoluble polymers of tyrosine derivatives found in and causing darkness in skin (skin pigmentation), 头发 hair, 和羽毛可防止日光灼伤。胡萝卜素产生黄和红。皮肤黑素是由黑素细胞产生的 and feathers providing protection against sunburn induced by sunlight. carotenes contribute yellow and red coloration. Dermal melanin is produced by melanocytes, 在表皮的基底层中发现。尽管 类皮肤中黑素细胞的浓度通常相似 which are found in the stratum basale of the epidermis. Although human beings generally possess a similar concentration of melanocytes in their skin, 某些个体和种族中的黑素细胞更频繁或更不频繁地表达产生黑素的基因 the melanocytes in some individuals and races more frequently or less frequently express the melanin-producing genes, 从而赋予或多或少的皮肤黑素浓度。一些个别的动物和 类的体内没有或只有很少的黑素 thereby conferring a greater or lesser concentration of skin melanin. Some individual animals and humans have no or very little melanin in their bodies, 这就是苦参。 which is a condition known as albinism. 较高的Eumelanin水平也可能是不利的 Higher eumelanin levels also can be a disadvantage, 然而 however, 除了对维生素D缺乏症的高度重视之外。深色皮肤是激光去除口酒污渍的复合物因素。有效治疗白皙的皮肤 beyond a higher disposition toward vitamin D deficiency. Dark skin is a complicating factor in the laser removal of port-wine stains. Effective in treating fair skin, 通常,在亚洲 和非洲 后裔中,激光在去除葡萄酒酒渍方面效果不佳。肤色较黑的 中较高的黑素浓度仅会扩散并吸收激光 lasers generally are less successful in removing port-wine stains in Asians and people of African descent. Higher concentrations of melanin in darker-skinned individuals simply diffuse and absorb the laser radiation, 抑制目标组织的光吸收。黑素同样会使皮肤较黑的 的其他皮肤科疾病的激光治疗复合物化。 inhibiting light absorption by the targeted tissue. Melanin similarly can complicate laser treatment of other dermatological conditions in people with darker skin. 在显微镜下黑素是棕色的 Under the microscope melanin is brown, 苯乙醛是一种重要的与氧化有关的醛。暴露于苯乙烯会产生苯乙醛作为次生代谢产物。苯乙烯被认为是 毒物 non-refractile and finely granular with individual granules having a diameter of less than 800 nanometers. This differentiates melanin from common blood breakdown pigments which are larger, 块状且易折射,颜色范围从绿到黄或红棕色。在色素沉着的病变中 chunky and refractile and range in color from green to yellow or red-brown. In heavily pigmented lesions, 黑素的密集聚集体会掩盖组织学细节。高锰酸钾的稀溶液是一种有效的黑素漂白剂。 dense aggregates of melanin can obscure histologic detail. A dilute solution of potassium permanganate is an effective melanin bleach. 导致皮肤变黑的色素 Pigments causing darkness in skin, 头发 hair, 羽毛 feathers, 等是不规则的聚合物结构,分为三类 etc. They are irregular polymeric structures and are divided into three groups: 植物界中的异源黑素 allomelanins和动物界中的洋红素 葡聚糖 eumelanins和蝴蝶素 phaeomelanins。 当皮肤色素沉着作为种族特征与社会地位或其他 类属性相关联时 When skin pigmentation as a characteristic of race is linked to social status or other human attributes, 这种现象被称为种族主义。许多 和社会将种族主义与种族主义观念和制度重叠,这些观念和制度任意赋予 们以一种固有的优越感或自卑感 this phenomenon is known as racialism. Many people and societies overlay racialism with racist perceptions and systems which arbitrarily assign to groups of people a status of inherent superiority or inferiority, 基于肤色或种族分类的特权或劣势。种族隔离时代的南非是白 至上主义社会的一个例子,它基于肤色对权力和特权进行分层的系统 privilege or disadvantage based on skin color or racial classification. Apartheid-era South Africa is an example of a white supremacist society based on a system of stratification of power and privilege by skin color, as 好 well as 种族的 racial 混合物 ad混合物 mixture. 类似 Similar 例子 例 examples can be 发现 found in Brazil's 高度 highly 社交上 社会的 socially 颜色分层 颜色 color-stratified 社会 society; and, 在美国。 in the U.S., 白 控制和黑 控制机构的种族隔离和制度种族主义 segregation and institutional racism on the part of white-controlled and black-controlled institutions, and 内部 internal '颜色 color 意识 consciousness' on the 部分 part of some 民族 ethnic 少数族裔 minorities. 偏见 Prejudice 反对 against people with 更多 more 高度 highly 着色的 颜料 pigmented skin is the 最 most 无处不在 pervasive form of 颜色 color 偏压 bias. 许多 Many other 社团 societies 保持 remain 非正式地 informally 分为 divided on the 基础 basis of skin 颜色 color and, 经常 often, 相关种族。 (另请参阅殖民主义 related ethnicity. (See also colonialism, 纳粹主义 Nazism, 色素专制和制度种族主义。) pigmentocracy and institutional racism.) 因为黑素是小分子的聚集体 Because melanin is an aggregate of smaller component molecules, 蜡状的。非常实质性的ct告诉我们它有一种“强大而甜美的菠萝味”。比己酸烯丙酯更顺滑,更甜。果味类似于乙酸芳樟酯。从四月到七月收获的。切割后立即将新鲜原料加工,以充分保留芳香性。莳萝精油具有新鲜的特征 there are a number of different types of melanin with differing proportions and bonding patterns of these component molecules. Both pheomelanin and eumelanin are found in human skin and hair, 但是Eumelanin是 类中最丰富的黑素 but eumelanin is the most abundant melanin in humans, 以及最有可能缺乏苦参的形式。 as well as the form most likely to be deficient in albinism. 在皮肤中局部存在黑素的地方会形成雀斑和痣。它们与皮肤苍白高度相关。 Freckles and moles are formed where there is a localized concentration of melanin in the skin. They are highly associated with pale skin. 黑素是一种生物聚合物和一种橙花肽。在1970年代初期 Melanin is a biopolymer and a neuropeptide. In the early 1970s, 约翰·麦金尼斯 John McGinness, 彼得·科里 Peter Corry, 彼得·普斯图尔(peter proctor)报告说,黑素是一种高电导率的有机半导体(科学 and Peter Proctor reported that melanin is a high-conductivity organic semiconductor (Science, 第183章 vol 183, 853-855(1974))。研究表明,黑素可作为电压控制的固态阈值开关。进一步 853-855 (1974)). Studies revealed that melanin acted as a voltage-controlled solid-state threshold switch. Further, 开关时它会发出电致发光的闪光。 it emitting a flash of light electroluminescence when it switched. 大约有十种不同类型的眼皮肤苦参 There are approximately ten different types of oculocutaneous albinism, 这主要是常染色体隐性遗传疾病。某些种族的不同形式的发生率较高。例如 which is mostly an autosomal recessive disorder. Certain ethnicities have higher incidences of different forms. For example, 最常见的类型 the most common type, 称为2型眼皮肤苦参(oca2) called oculocutaneous albinism type 2 (OCA2), 亚致死浓度的牛至属金黄熊果缺乏对金黄熊果的直接保护或交叉保护的诱导。肉类培养基中的精油和香芹酚。 is especially frequent among people of indigenous African descent. It is an autosomal recessive disorder characterized by a congenital reduction or absence of melanin pigment in the skin, 头发和眼睛。非洲裔美国 中oca2的估计频率为十分之一 hair and eyes. The estimated frequency of OCA2 among African-Americans is 1 in 10,000, 与36分之一的频率形成对比 which contrasts with a frequency of 1 in 36,白 中有000 。在一些非洲国家 000 in white Americans . In some African nations, 疾病的发生频率更高 the frequency of the disorder is even higher, 2分之1 ranging from 1 in 2,000比5 000 to 1 in 5,000.苦参的另一种形式 000. Another form of Albinism, the '黄 yellow 眼皮的 oculocutaneous 苦参 albinism', 在阿米什 中似乎更为普遍 appears to be more prevalent among the Amish, 他们主要来自瑞士和德国。患有这种ib变异的 出生时通常有白发和皮肤 who are of primarily Swiss and German ancestry. People with this IB variant of the disorder commonly have white hair and skin at birth, 但婴儿期会迅速发展正常的皮肤色素沉着。 but rapidly develop normal skin pigmentation in infancy. 宽广地 Broadly, 黑素是任何聚乙炔 melanin is any of the polyacetylene, 聚苯胺 polyaniline, and 聚polypyrrole '黑 黑 blacks' and "棕色 browns 棕色 browns" or their 混合的 mixed 共聚物 co聚合物 聚合物 polymers. The 最 most 共同 common form of 生物 biological melanin is a 聚合物 polymer of either either or 都 both of 二 two 单体 monomer 分子 molecules: 吲哚醌 indolequinone, 和二羟基吲哚羧酸。相反 and dihydroxyindole carboxylic acid. In contrast, 有点花香让 联想到番红花花;典型的藏红花 some fungal melanin is polyacetylene black. Melanin exists in the plant, 动物界和原生界 animal and protista kingdoms, 用作颜料的地方黑素在古细菌界和细菌界的存在是该领域研究 员不断争论的问题。 [hmdb] where it serves as a pigment. The presence of melanin in the archaea and bacteria kingdoms is an issue of ongoing debate amongst researchers in the field. [HMDB]
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