甲基天冬氨酸 methyl aspartic acid
天冬氨酸 D-aspartic acid, 正甲基 N-methyl-
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笔记 Notes: 一种氨基酸 an amino acid that, 作为d-异构体 as the d-isomer, 是谷氨酸受体（受体）的nmda受体亚型的定义性激动剂 is the defining agonist for the nmda receptor subtype of glutamate receptors (receptors, nmda）。 n-甲基-d-天冬氨酸是一种在nmda受体上起特定激动剂作用的氨基酸衍生物 nmda). N-Methyl-D-aspartic acid is an amino acid derivative acting as a specific agonist at the NMDA receptor, 因此模仿了橙花递质谷氨酸对该受体的作用。与谷氨酸相反 and therefore mimics the action of the neurotransmitter glutamate on that receptor. In contrast to glutamate, nmda仅结合并调节上述受体 NMDA binds to and regulates the above receptor only, 但不是其他谷氨酸受体。 but not other glutamate receptors.
nmda NMDA is a 水 water-soluble 合成的 synthetic 物质 substance that is not 一般 正常 normally 发现 found in 生物 biological 组织 tissue. it It was 第一 first 合成的 synthesized in the 1960's. nmda NMDA is an 兴奋毒素 excitotoxin; 这个 this 特征 trait 已 has 应用领域 applications in 行为的 行为 behavioral 橙花科学 neuroscience 研究 research. The body of 工作 work 利用 utilizing 这个 this 技术 technique 下降 falls under the term "病灶 lesion 学习 studies." 研究 员 研究 Researchers 应用 apply nmda NMDA to 浸膏 specific 地区 regions of an (animal) subject's 脑 brain or spinal cord and 随后 subsequently 测试 test for the 行为 behavior of 利益 interest, 例如操作行为。如果行为受到损害 such as operant behavior. If the behavior is compromised, 这表明被破坏的组织是大脑区域的一部分，对这种行为的正常表达做出了重要贡献。 it suggests the destroyed tissue was part of a brain region that made an important contribution to the normal expression of that behavior.
nmda受体拮抗剂的例子是apv Examples of antagonists of the NMDA receptor are APV, 右美沙芬 dextromethorphan, 氯胺ketamine, 苯环利定（pcp） phencyclidine (PCP), 利鲁唑 riluzole, 和美金刚。它们通常被称为nmda受体拮抗剂。 （维基百科）[hmdb] and memantine. They are commonly referred to as NMDA receptor antagonists. (Wikipedia) [HMDB]
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