肉豆蔻酸己酯 hexyl myristate
tetradecanoic acid, 己酯 hexyl ester

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    42231-99-2十四酸 42231-99-2 Tetradecanoic acid,己酯 hexyl ester
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CAS号 CAS Number: 42231-99-2Picture of molecule3D/INCHI
ECHA EINECS - REACH 预注册 Pre-Reg:255-722-0
nikkaji网站 Nikkaji Web:J278.361D
XlogP3-AA:8.70(est) 8.70 (est)
分子量 Molecular Weight:312.53720000
式 Formula:c20 h40 o2 C20 H40 O2
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:flavor and fragrance agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
Flavis号码 FLAVIS Number:09.582(旧) 09.582 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:09.582十四酸己酯 09.582 hexyl tetradecanoate
 
物理性质 Physical Properties:
出现 Appearance:无色透明液体(est) colorless clear liquid (est)
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
沸点 Boiling Point: 359.00 to 362.00 °C. @ 760.00 mm 汞 Hg
蒸汽压力 Vapor Pressure:0.000019 毫米汞柱 mm汞 Hg @ 25.00 °C. (est)
闪点 Flash Point: 349.00 °F. tcc TCC ( 176.11 °C. )
logp(o / w) logP (o/w): 8.937(est) 8.937 (est)
溶于 Soluble in:
 alcohol
 水 water, 0.0003691 mg / l @ 25°c(est) 0.0003691 mg/L @ 25 °C (est)
不溶于 Insoluble in:
 水 water
类似物品 Similar Items:note
肉豆蔻酸异戊酯 isoamyl myristate
肉豆蔻酸丁酯 butyl myristate
肉豆蔻酸异丁酯 isobutyl myristate
肉豆蔻酸乙酯 ethyl myristate
肉豆蔻酸2-甲基丁酯 2-methyl butyl myristate
肉豆蔻酸甲酯 methyl myristate
肉豆蔻酸异丙酯 isopropyl myristate
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
tetradecanoic acid,己酯 hexyl ester
化学资源协会 Chemical sources Association Inc
需要这个物品来调味/食用吗? Need This Item for Flavor/Food?: 您 You can contact the 化学资源协会 Chemical sources Association Inc
 
安全信息 Safety Information:
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: flavor and fragrance agents
推荐使用肉豆蔻酸己酯的使用水平 Recommendation for hexyl myristate usage levels up to:
  香料浓缩物中的25.0000%。 25.0000 % in the fragrance concentrate.
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 0.61(微克/ 均/天) 0.61 (μg/capita/day)
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): 3900(微克/ /天) 3900 (μg/person/day)
关注点 Threshold of Concern:1800(微克/ /天) 1800 (μg/person/day)
结构类 Structure Class: I
 
根据委员会法规ec EC号的食品类别。 1565/2000(ec , 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the 行业 Industry the "正常 normal" use is 定义的 defined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 defined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (efsa EFSA, 2002i)。 2002i).
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm
 平均 average 用法 usage mg/kg kg最大 maximum 用法 usage mg/kg kg
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): 7.0000035.00000
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): 5.0000025.00000
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): 10.0000050.00000
加工水果(04.1) Processed fruit (04.1): 7.0000035.00000
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): --
糖果(05.0) Confectionery (05.0): 10.0000050.00000
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): 5.0000025.00000
烘焙用具(07.0) Bakery wares (07.0): 10.0000050.00000
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): 2.0000010.00000
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : 2.0000010.00000
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): --
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): --
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): 5.0000025.00000
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): 10.0000050.00000
不含醇 Non-alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): 5.0000025.00000
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): 10.0000050.00000
即食美味(15.0) Ready-to-eat savouries (15.0): 20.00000100.00000
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 5.0000025.00000
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

调味组评估2 Flavouring Group Evaluation 2, 版本1(fge.02) Revision 1 (FGE.02) : 无香香石竹芽油无萜丁香无香紫丁香无香紫丁香香油无萜香精无香香蒲无香紫草香油无萜桃金娘香石竹芽油无萜香精 Branched- and straight-chain aliphatic saturated primary alcohols and related esters of primary alcohols and straight-chain carboxylic acids and one straight-chain aldehyde from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, 调味料 Flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC)
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
EPA物质注册服务(tsca TSCA) :42231-99-2
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :170623
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:数据 Data
十四酸己酯 hexyl tetradecanoate
chemidplus Chemidplus:0042231992
 
参考资料 References:
 十四酸己酯 hexyl tetradecanoate
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):170623
pubchem(sid) Pubchem (sid):135125880
信息基 Pherobase:视图 View
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEMBL:视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
化学蜘蛛 ChemSpider:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None found
 
潜在用途 Potential Uses:
没找到 None found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 十四酸己酯 hexyl tetradecanoate
 tetradecanoic acid 己酯 hexyl ester
 tetradecanoic acid, 己酯 hexyl ester
 

文章 Articles:

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已发布 PubMed:β-雌二醇对dna合成的刺激在hepg2和mcf7细胞中需要不同的pkc亚型。 beta-estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells.
已发布 PubMed:抗心绞痛药物贝普利对 中性粒细胞胞内ca2 +释放和胞外ca2 +内流的影响。 Effect of the antianginal drug bepridil on intracellular Ca2+ release and extracellular Ca2+ influx in human neutrophils.
已发布 PubMed:营养脂质乳剂可调节细胞信号传导和 类嗜中性粒细胞的活化。 Nutritional lipid emulsions modulate cellular signaling and activation of human neutrophils.
已发布 PubMed:hep-2细胞中胞外核苷酸诱导的胞内钙振荡的特征。 Characterization of intracellular calcium oscillations induced by extracellular nucleotides in HEp-2 cells.
已发布 PubMed:rap1被促红细胞生成素或白介素3激活,并参与调节beta1整合素介导的造血细胞粘附。 Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion.
已发布 PubMed:脂肪族(正壬烷)的影响 The effects of aliphatic (n-nonane), 萘(1 naphtenic (1,2, 4-三甲基环己烷) 4-trimethylcyclohexane), 和芳香(1 and aromatic (1,2, 中性粒细胞粒细胞呼吸爆发时的4-三甲苯)碳氢化合物 4-trimethylbenzene) hydrocarbons on respiratory burst in human neutrophil granulocytes.
已发布 PubMed:db-camp分化的hl-60细胞中fmlp诱导的花生四烯酸释放独立于磷脂酰肌醇4 fMLP-induced arachidonic acid release in db-cAMP-differentiated HL-60 cells is independent of phosphatidylinositol-4, 5-双磷酸特定磷脂酶c激活和胞质磷脂酶a(2)激活。 5-bisphosphate-specific phospholipase C activation and cytosolic phospholipase A(2) activation.
已发布 PubMed: 一氧化氮激活负鼠肾细胞中的pkcα alpha并抑制na + -k + -atpase。
已发布 PubMed:低渗诱导的大鼠大脑皮层氨基酸释放 Hyposmotically induced amino acid release from the rat cerebral cortex: 磷脂酶和蛋白激酶的作用。 role of phospholipases and protein kinases.
已发布 PubMed:磷脂酶c抑制剂u73122抑制佛波酯诱导的血小板活化。 The phospholipase C inhibitor U73122 inhibits phorbol ester-induced platelet activation.
已发布 PubMed: 去甲肾上腺素刺激培养的牛子宫内膜细胞中前列腺素f2α alpha的产生。
已发布 PubMed:细胞表面受体可能参与鞘氨醇1-磷酸酯诱导的c6胶质瘤细胞中细胞外信号调节激酶的活化。 Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells.
已发布 PubMed:[3h]-吡拉明结合和组胺诱导的肌醇磷酸生成的药理学 Pharmacology of [3H]-pyrilamine binding and of the histamine-induced inositol phosphates generation, 角膜上皮细胞的胞内钙离子动员和细胞因子释放。 intracellular Ca2+ -mobilization and cytokine release from human corneal epithelial cells.
已发布 PubMed:ras介导的信号转导通过碱性成纤维细胞生长因子增强海马橙花元去极化诱导的ca2 +反应的潜在作用。 A potential role of Ras-mediated signal transduction for the enhancement of depolarization-induced Ca2+ responses in hippocampal neurons by basic fibroblast growth factor.
已发布 PubMed:麦丁达比犬肾脏细胞中缓激肽引起的ca2 +动员。 Bradykinin-evoked Ca2+ mobilization in Madin Darby canine kidney cells.
已发布 PubMed:样生长因子i和ii对成年大鼠肝细胞原代培养中dna合成和增殖的影响 Effects of insulin-like growth factor I and II on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
已发布 PubMed:去甲肾上腺素对负鼠肾细胞中血管紧张素原基因表达的影响的分子机制。 Molecular mechanism(s) of action of norepinephrine on the expression of the angiotensinogen gene in opossum kidney cells.
已发布 PubMed:u73122阻止了cgmp诱导的海胆卵中钙的释放。 U73122 blocked the cGMP-induced calcium release in sea urchin eggs.
已发布 PubMed:诱导的海马星形胶质细胞中钙离子的调节α1肾上腺素刺激的抑制作用。 Modulation of mechanically induced calcium waves in hippocampal astroglial cells. Inhibitory effects of alpha 1-adrenergic stimulation.
已发布 PubMed:酶c-β3磷酸化对 样物质激活的磷酸肌醇反应的快速减弱的贡献。 Contribution of phospholipase C-beta3 phosphorylation to the rapid attenuation of opioid-activated phosphoinositide response.
已发布 PubMed:鸟耳蜗核橙花元中[ca2 +] i的活性依赖性调节 Activity-dependent regulation of [Ca2+]i in avian cochlear nucleus neurons: 蛋白激酶a和c的作用及其与细胞死亡的关系。 roles of protein kinases A and C and relation to cell death.
已发布 PubMed:缓激肽对信号转导的影响 Effects of bradykinin on signal transduction, 细胞增殖 cell proliferation, 和细胞因子 and cytokine, 前列腺素e2和胶原酶-1从 角膜上皮细胞释放。 prostaglandin E2 and collagenase-1 release from human corneal epithelial cells.
已发布 PubMed:去氧肾上腺素增强了血小板衍生的生长因子诱导的成年大鼠肝细胞在原代培养物中的增殖。 Proliferation of adult rat hepatocytes in primary cultures induced by platelet-derived growth factor is potentiated by phenylephrine.
已发布 PubMed:蛋白激酶c介导p2u嘌呤能受体抑制血管内膜边缘细胞顶膜中k +通道。 Protein kinase C mediates P2U purinergic receptor inhibition of K+ channel in apical membrane of strial marginal cells.
已发布 PubMed:p2u嘌呤能受体通过前庭暗细胞中的蛋白激酶c抑制顶端isk / kvlqt1通道。 P2U purinergic receptor inhibits apical IsK/KvLQT1 channel via protein kinase C in vestibular dark cells.
已发布 PubMed:缓激肽和凝血酶诱导的内皮通透性增加独立于磷脂酶c发生,但需要蛋白激酶c激活。 Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation.
已发布 PubMed:甲状腺素对干扰素-γ诱导的抗 状态的增强作用需要pka和pkc活性。 Potentiation by thyroxine of interferon-gamma-induced antiviral state requires PKA and PKC activities.
已发布 PubMed: 嗜中性粒细胞继发颗粒胞吐作用独立于蛋白激酶激活,并被钙调蛋白活性修饰。 Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
已发布 PubMed:u-73122 U-73122: 一种有效的 类多形核中性粒细胞在生物表面粘附和与粘附相关的效应子功能的抑制剂。 a potent inhibitor of human polymorphonuclear neutrophil adhesion on biological surfaces and adhesion-related effector functions.
已发布 PubMed:内皮素-1诱导表达 内皮素的中国仓鼠 细胞的促有丝分裂反应 Endothelin-1-induced mitogenic responses of Chinese hamster ovary cells expressing human endothelinA: 渥曼青霉素敏感性信号通路的作用。 the role of a wortmannin-sensitive signaling pathway.
已发布 PubMed:卵磷脂微乳的假三元相图 Pseudo-ternary phase diagrams of lecithin-based microemulsions: 磷酸单烷基酯的影响。 influence of monoalkylphosphates.
已发布 PubMed:蛋白激酶c的激活刺激大鼠肾收集小管中的营地磷酸二酯酶。 Activation of protein kinase C stimulates cAMP phosphodiesterase in rat renal collecting tubule.
已发布 PubMed:脂蛋白脂肪酶诱导肿瘤坏死因子α基因表达需要蛋白激酶c激活。 Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase requires protein kinase C activation.
已发布 PubMed:大鼠甲状腺髓样癌6-23细胞中由α1b-肾上腺素受体激活产生的电压依赖性钙内流增加。 Increased voltage-dependent calcium influx produced by alpha 1B-adrenergic receptor activation in rat medullary thyroid carcinoma 6-23 cells.
已发布 PubMed:一种新型的磷脂酶c抑制剂和佛波醇酯揭示了大鼠 瘤细胞中凝血酶和甲状旁腺激素刺激的信号通路的选择性调节。 A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells.
已发布 PubMed:激动剂刺激的促性腺激素中磷脂酶-c和-d的顺序激活。 Sequential activation of phospholipase-C and -D in agonist-stimulated gonadotrophs.
已发布 PubMed:无毛豚鼠模型的局部皮肤中白三烯拮抗剂的体外皮肤渗透和保留研究。 Studies of in vitro skin permeation and retention of a leukotriene antagonist from topical vehicles with a hairless guinea pig model.
已发布 PubMed:吡咯烷酮衍生物对5-氟尿嘧啶透皮渗透的增强作用 Enhancing effect of pyrrolidone derivatives on transdermal penetration of 5-fluorouracil, 曲安奈德 triamcinolone acetonide, 消炎痛 indomethacin, 和氟比洛芬。 and flurbiprofen.
已发布 PubMed: 类生长激素刺激 类培养的淋巴细胞(im-9)的生长,并通过下调激素受体来抑制佛波二酯。 55的磷酸化可能参与 Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,与受体000分子量相关的蛋白质在下调。 000 molecular weight protein associated with the receptor in the down-regulation.
已发布 PubMed:胎盘微粒体中前列腺素ω-羟化酶活性的细胞色素p-450的存在 Occurrence of cytochrome P-450 with prostaglandin omega-hydroxylase activity in rabbit placental microsomes.
已发布 PubMed:3-甲基胆碱治疗的兔肾皮质微粒体中存在多种形式的细胞色素p-450。 Multiple forms of cytochrome P-450 in kidney cortex microsomes of rabbits treated with 3-methylcholanthrene.
已发布 PubMed: 色素b5对兔肾皮质微粒体部分纯化的细胞色素p-450催化的脂肪酸ω-和(欧米茄 欧米茄 omega-1)-羟基化的影响
已发布 PubMed:兔肠粘膜微粒体中的脂肪酸ω和(ω-1)羟基化。 Fatty acid omega and (omega-1)-Hydroxylation in rabbit intestinal mucosa microsomes.
 
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