arctigenin
(3r (3R,4r)-4-[(3 4R)-4-[(3,4-二甲氧基苯基)甲基]二氢-3-[(4-羟基-3-甲氧基苯基)甲基] -2(3h)-呋喃酮 4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone

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    7770-78-7 Arctigenin> 98% 7770-78-7 Arctigenin >98%
    arctigenin是Arctii arctiin Arctii arctiin的糖苷配基,是在菊科的某些植物中发现的木脂素。它在玻璃中显示出抗 和抗癌作用。它显示出对甲型流感 有效的体外抗 活性(a / nws / 33 , h1n1)(ifv)。 H1N1) (IFV).
Name:(3r (3R,4r)-4-[(3 4R)-4-[(3,4-二甲氧基苯基)甲基] -3-[(4-羟基-3-甲氧基苯基)甲基]氧杂-2--2- 4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
CAS号 CAS Number: 7770-78-7Picture of molecule3D/INCHI
FDA UNII:U76MR9VS6M
nikkaji网站 Nikkaji Web:J16.086E
MDL :mfcd00870597 MFCD00870597
XlogP3-AA:3.60(est) 3.60 (est)
分子量 Molecular Weight:372.41748000
式 Formula:c21 h24 o6 C21 H24 O6
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:antioxidants
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
沸点 Boiling Point: 567.00 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 390.00 °F. tcc TCC ( 198.80 °C. ) (est)
logp(o / w) logP (o/w): 2.470(est) 2.470 (est)
溶于 Soluble in:
 水 water, 25°C(23.08 mg / l)(est) 23.08 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: antioxidants
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
牛蒡皂苷元> 98% Arctigenin >98%
气味 Odor: characteristic
采用 Use: arctigenin是Arctii arctiin Arctii arctiin的糖苷配基,是在菊科的某些植物中发现的木脂素。它在玻璃中显示出抗 和抗癌作用。它显示出对甲型流感 有效的体外抗 活性(a / nws / 33 , h1n1)(ifv)。 H1N1) (IFV).
碳合蛋白 Carbosynth
仅供实验/研究使用。 For experimental / research use only.
Arctigenin
库姆波 Coompo
仅供实验/研究使用。 For experimental / research use only.
Arctigenin from 植物 厂 Plants ≥98%
气味 Odor: characteristic
采用 Use: arctigenin是Arctii arctiin Arctii arctiin的糖苷配基。它具有抗 和抗癌作用。 在这里发现它可以激活amp激活的蛋白激酶(ampk) Here it was found to activate AMP-activated protein kinase (AMPK), 以及发生这种情况的机制 and the mechanism by which this occurred, 以及对葡萄糖和脂质代谢的影响。 Arctigenin通过抑制呼吸道复合物而作为ampk的有效间接激活剂的新作用 as well as the effects on glucose and lipid metabolism were investigated. A new role for arctigenin as a potent indirect activator of AMPK via inhibition of respiratory complex I, 2-(7-(二乙氨基)-2-oxo-2h-1-苯并吡喃-3-基)-2-(7-(二乙氨基)-2-oxo-2h-1-苯并吡喃-3-基)苯并恶唑- 5-磺酰胺2-(7-(二乙氨基)-2-氧代-2h-1-苯并吡喃-3-基)苯并恶唑-5-磺酰胺2- [7-(二乙氨基)-2-氧代-2h-1-苯并吡喃-3- yl] benzoxazole-5-sulphonamide2- [7-(diethylamino)-2-oxo铬 chromen-3-yl] -1 p210-远离热源/火花/明火/热表面。 — p233-保持容器密闭p240-地面/粘结容器和接收设备p241-使用防爆电气/通风/照明/照明/安全设备p242-仅使用无火花的工具p243-采取预防措施防静电措施。p273-避免释放到环境中。p280-戴防护手套/穿防护服/戴防护眼罩/戴面罩。p303 + p361 + p353-如果在皮肤(或头发)上 Arctigenin selectively promoted glucose-starved A549 tumor cells to undergo necrosis by inhibiting mitochondrial respiration. arctigenin elevated cellular level of reactive oxygen species (ROS) and blocked cellular energy metabolism in the glucose-starved tumor cells. combined arctigenin with the glucose analogue 2-deoxyglucose (2DG) and examined their effects on tumor cell growth. The combination of arctigenin and 2DG may represent a promising new cancer therapy with minimal normal tissue toxicity. 牛蒡皂苷元抑制t淋巴细胞增殖并降低il-2的基因表达 Arctigenin inhibited T lymphocyte proliferation and decreased the gene expression of IL-2, ifn-?和nf-at。 IFN-? and NF-AT.
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
牛蒡皂苷元≥97% Arctigenin ≥97%
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
(-)-arctigenin (-)-Arctigenin
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: antioxidants
推荐的arctigenin使用水平 Recommendation for arctigenin usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐的arctigenin风味使用水平 Recommendation for arctigenin flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :64981
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
(3r (3R,4r)-4-[(3 4R)-4-[(3,4-二甲氧基苯基)甲基] -3-[(4-羟基-3-甲氧基苯基)甲基]氧杂-2--2- 4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
chemidplus Chemidplus:0007770787
 
参考资料 References:
 (3r (3R,4r)-4-[(3 4R)-4-[(3,4-二甲氧基苯基)甲基] -3-[(4-羟基-3-甲氧基苯基)甲基]氧杂-2--2- 4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):64981
pubchem(sid) Pubchem (sid):135022167
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
KEGG (GenomeNet):C10545
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB30087
食物 FooDB:FDB001442
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
efsa EFSA更新监测食品中呋喃水平的结果 :阅读报告 Read Report
efsa EFSA以前的报告 : 食品中呋喃水平监测的结果 Results on the monitoring of furan levels in food:阅读报告 Read Report
欧洲反腐败委员会关于食品中呋喃的临时调查结果的efsa EFSA报告 :阅读报告 Read Report
 
潜在 有力的 Potential 搅拌机 Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 牛d burdock
搜索 Search Trop Picture
 牛d水果 burdock fruit
搜索 Search Trop Picture
 牛d种子 burdock seed
搜索 Search Trop Picture
 卡顿 cardoon
搜索 Search Trop Picture
 连翘 forsythia viridissima
搜索 Search Trop Picture
 番薯 ipomoea cairica
搜索 Search Trop Picture
 蓟蓟 thistle holy thistle
搜索 Search Trop Picture
 哥王 wikstroemia indica
搜索 Search Trop Picture
 
同义词 Synonyms:
 弓形虫 arcti基因 genen
 二苄基丁内酯 dibenzylbut butyrolactone 木质素 利格南 lignanolide
(3r (3R,4r)-4-(3分 4R)-4-(3,4-dimethoxy-benzyl)-3-(4-hydroxy-3-methoxy-benzyl)-dihydro-呋喃 furan-2-one
(3r (3R,4r)-4-(3分 4R)-4-(3,4-dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)-dihydro呋喃 furan-2(3H)-one
(3r (3R,4r)-4-(3分 4R)-4-(3,4-dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydro呋喃 furan-2(3H)-one
(3r (3R,4r)-4-((3 4R)-4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-2(3H)-呋喃酮 -呋喃 furanone
(3r (3R,4r)-4-[(3 4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
4-[(3,4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-(3r (3R-trans)-2(3H)-呋喃酮 -Furanone
4-[(3,4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-(3r (3R,4r)- 4R)-2(3H)-呋喃酮 -Furanone
(3r (3R,4r)-4-[(3 4R)-4-[(3,4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-呋喃酮 -呋喃 furanone
2(3H)-呋喃 furanone, 4-((3,4-二甲氧基苯基)甲基)二氢-3-((4-羟基-3-甲氧基苯基)甲基)- 4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3r (3R,4r)- 4R)-
2(3H)-呋喃 furanone, 4-[(3,4-二甲氧基苯基)甲基]二氢-3-[(4-羟基-3-甲氧基苯基)甲基]- 4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3r (3R,4r)- 4R)-
 

文章 Articles:

已发布 PubMed:Arctigenin通过mtorc1依赖性途径抑制th1和th17细胞分化,从而发挥抗结肠炎功效。 Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway.
已发布 PubMed:Arctigenin拮抗盐皮质激素受体,以抑制na / k-atpase的转录。 Arctigenin antagonizes mineralocorticoid receptor to inhibit the transcription of Na/K-ATPase.
已发布 PubMed:Arctigenin通过ampk和ppar-γ/ror-γt信号转导抑制th17细胞并改善实验性自身免疫性脑脊髓炎。 Arctigenin Suppress Th17 Cells and Ameliorates Experimental Autoimmune Encephalomyelitis Through AMPK and PPAR-γ/ROR-γt Signaling.
已发布 PubMed:口服和静脉内给药后正常和2型糖尿病大鼠中Arctigenin的药代动力学比较。 Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration.
已发布 PubMed:在小鼠模型中,arctigenin可防止脂多糖诱导的肺氧化应激和炎症,其作用是通过抑制mapk Arctigenin Protects against Lipopolysaccharide-Induced Pulmonary Oxidative Stress and Inflammation in a Mouse Model via Suppression of MAPK, ho-1 HO-1, 和inos信号。 and iNOS Signaling.
已发布 PubMed:十种选择的姜科植物根茎在民用医学中的总酚类化合物和水提取物的体外清除自由基能力的评估 Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.
已发布 PubMed:Arctigenin对gk大鼠合并高血压大血管病的保护作用 [Protective effect of arctigenin in GK rats combined with hypertension macroangiopathy].
已发布 PubMed:arctigenin对类风湿节螺藻成纤维细胞样滑膜细胞的影响。 The effects of arctigenin on human rheumatoid arthritis fibroblast-like synoviocytes.
已发布 PubMed:Arctigenin, 天然木脂素化合物 a Natural Lignan Compound, 通过抑制pi3-k / akt信号传导诱导肝癌细胞凋亡死亡。 Induces Apoptotic Death of Hepatocellular Carcinoma Cells via Suppression of PI3-K/Akt Signaling.
已发布 PubMed:pdk1 / akt / pde4d轴被天然制剂arctigenin鉴定为与β2ar激动剂协同治疗哮喘的靶标。 PDK1/Akt/PDE4D axis identified as a target for asthma remedy synergistic with β2 AR agonists by a natural agent arctigenin.
已发布 PubMed: arctigenin通过inos / no / stat3 / 生存素 survivin信号传导促进 癌细胞凋亡。
已发布 PubMed:通过调节pi3k / akt信号通路在大鼠原代星形胶质细胞中,arctigenin增加了血氧合酶1基因的表达。 Arctigenin Increases Hemeoxygenase-1 Gene Expression by Modulating PI3K/AKT Signaling Pathway in Rat Primary Astrocytes.
已发布 PubMed:通过调节抗氧化剂途径,arctigenin可增强久坐大鼠的游泳耐力。 Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways.
已发布 PubMed:牛蒡皂苷元和苦参素醇对T细胞淋巴瘤细胞ccrf-cem的细胞毒性。 Cytotoxicity of arctigenin and matairesinol against the T-cell lymphoma cell line CCRF-CEM.
已发布 PubMed:设计和合成用于改善代谢紊乱的新型arctigenin类似物。 Design and synthesis of novel arctigenin analogues for the amelioration of metabolic disorders.
已发布 PubMed: 通过下调生存素 survivin表达,arctinin增强 非小细胞肺癌h460细胞对顺铂的化学敏感性。
已发布 PubMed:arctigenin通过抑制钙调磷酸酶依赖性和成骨细胞依赖性nfatc1途径来抑制破骨细胞的分化和功能 Arctigenin inhibits osteoclast differentiation and function by suppressing both calcineurin-dependent and osteoblastic cell-dependent NFATc1 pathways.
已发布 PubMed:Arctigenin通过g0 / g1期细胞周期阻滞抑制激活的星状细胞增殖 The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: 通过干扰pi3k / akt / foxo3a信号传导途径持续诱导p27(kip1)。 persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway.
已发布 PubMed:酶水解-高速逆流色谱法分离和纯化弓形虫中箭毒苷原 Isolation and purification of arctigenin from Fructus Arctii by enzymatic hydrolysis combined with high-speed counter-current chromatography.
已发布 PubMed:Arctigenin, 牛arc子的有效成分。 a Potent Ingredient of Arctium lappa L., 诱导内皮一氧化氮合酶,并通过pi3k / akt途径减轻蛛网膜下腔出血所致血管痉挛。 Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model.
已发布 PubMed:Arctigenin抑制口腔鳞状细胞癌中vegf蛋白的表达 [Suppression of VEGF protein expression by arctigenin in oral squamous cell carcinoma].
已发布 PubMed:牛蒡皂苷元通过影响钙的跨膜流动对支气管表现出松弛作用。 Arctigenin exhibits relaxation effect on bronchus by affecting transmembrane flow of calcium.
已发布 PubMed:抑制血管生成 Inhibition of angiogenesis: 草药复方Arctigenin的新型抗肿瘤机制。 a novel antitumor mechanism of the herbal compound arctigenin.
已发布 PubMed: lc LC / MS / MS方法的开发,以确定大鼠血浆中的Arctigenin : 它在药代动力学研究中的应用。 its application to a pharmacokinetic study.
已发布 PubMed:牛蒡皂苷元通过ppar-γ/lxr-α信号通路促进thp-1巨噬细胞的胆固醇外流。 Arctigenin promotes cholesterol efflux from THP-1 macrophages through PPAR-γ/LXR-α signaling pathway.
已发布 PubMed:Arctigenin在肠道的广泛首过代谢 Extensive intestinal first-pass metabolism of arctigenin: 通过同时监测母体药物及其主要代谢物来证明。 evidenced by simultaneous monitoring of both parent drug and its major metabolites.
已发布 PubMed:Arctigenin对mpp +和mptp诱导的橙花毒性的保护作用。 Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity.
已发布 PubMed:皂苷元酯和醚衍生物作为ampk的活化剂的合成及生物学评价。 Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK.
已发布 PubMed:阿奇霉素与槲皮素的组合可协同增强前列腺癌细胞的抗增殖作用。 Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells.
已发布 PubMed:通过抑制pi3k / akt途径并使m1巨噬细胞极化为m2样巨噬细胞,arctigenin改善了体内和体外的炎症。 Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
已发布 PubMed:水解是Arctigenin在体内的主要代谢途径 Hydrolysis is the dominating in vivo metabolism pathway for arctigenin: 大鼠口服后lc / ms / ms鉴定arctigenin的新代谢产物。 identification of novel metabolites of arctigenin by LC/MS/MS after oral administration in rats.
已发布 PubMed:鉴定和表征arctigenin的体外葡萄糖醛酸苷化反应的 udp-葡萄糖醛酸转移酶。 Identification and characterization of human UDP-glucuronosyltransferases responsible for the in-vitro glucuronidation of arctigenin.
已发布 PubMed:Arctigenin对映体的抗紧缩活性 Antiausterity activity of arctigenin enantiomers: (2r的重要性 importance of (2R,3r)-精华/精粹/精萃配置。 3R)-absolute configuration.
已发布 PubMed:Arctigenin, 潜在的抗心律不齐药 a potential anti-arrhythmic agent, 通过调节多离子通道抑制乌头碱引起的心律失常。 inhibits aconitine-induced arrhythmia by regulating multi-ion channels.
已发布 PubMed:在大鼠静脉内和口服给药后阐明Arctigenin的药代动力学 Elucidation of arctigenin pharmacokinetics after intravenous and oral administrations in rats: 通过半力学药代动力学模型整合体外和体内发现。 integration of in vitro and in vivo findings via semi-mechanistic pharmacokinetic modeling.
已发布 PubMed:来自牛uc子的牛d子苷元(牛bur子)在caco-2细胞单层中增强肠屏障功能 Arctigenin from Fructus Arctii (Seed of Burdock) Reinforces Intestinal Barrier Function in Caco-2 Cell Monolayers.
已发布 PubMed:皂苷元介导的针对 肺腺癌细胞系的特异性细胞毒性的机制 Mechanism of arctigenin-mediated specific cytotoxicity against human lung adenocarcinoma cell lines.
已发布 PubMed:牛蒡皂苷元通过芯片相关的蛋白酶体途径促进诱导型一氧化氮合酶的降解,并抑制其酶活性。 Arctigenin promotes degradation of inducible nitric oxide synthase through CHIP-associated proteasome pathway and suppresses its enzyme activity.
已发布 PubMed: 超滤法测定Arctii arctiin Arctii arctiin和arctigenin的血浆蛋白结合率
已发布 PubMed:Arctigenin, 饮食中的植物雌激素 a dietary phytoestrogen, 通过ros / p38 mapk途径和表观遗传调控诱导雌激素受体阴性乳腺癌细胞凋亡。 induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation.
已发布 PubMed:通过诱导细胞周期停滞和凋亡,arctinin在膀胱癌t24细胞系中具有抗肿瘤活性。 Arctigenin anti-tumor activity in bladder cancer T24 cell line through induction of cell-cycle arrest and apoptosis.
已发布 PubMed: (-)arctigenin和(+)松脂醇 pinoresinol是 甲状腺激素受体β的拮抗剂。
已发布 PubMed: 茉莉花蜡茉莉花蜡茉莉花。大花花卉cera茉莉花officinale var。从西班牙茉莉花中提取的大花花卉蜡
已发布 PubMed:Arctigenin 有效 有效 影响 effectively 改善 amelio率 rates 记忆 memory 减损 impairment in Alzheimer's 疾病 disease 模型 model 老鼠 mice 定位 目标 targeting 都 both β淀粉样蛋白 β-amyloid 生产 production and 间隙 clearance.
已发布 PubMed:结合arctigenin增强化学预防作用 Increased chemopreventive effect by combining arctigenin, 绿茶中的多酚和姜黄素可用于前列腺癌和乳腺癌细胞。 green tea polyphenol and curcumin in prostate and breast cancer cells.
已发布 PubMed:在抑制葡萄糖剥夺的情况下,Arctigenin通过抑制细胞能量代谢而优先诱导肿瘤细胞死亡。 Arctigenin preferentially induces tumor cell death under glucose deprivation by inhibiting cellular energy metabolism.
已发布 PubMed:牛蒡皂苷元抑制骨髓源性巨噬细胞中核因子κb配体(rankl)介导的破骨细胞分化的受体激活剂。 Arctigenin suppresses receptor activator of nuclear factor κB ligand (RANKL)-mediated osteoclast differentiation in bone marrow-derived macrophages.
已发布 PubMed:Arctigenin, 天然化合物 a natural compound, 通过抑制线粒体复合体i激活Amp激活的蛋白激酶,并改善ob / ob小鼠的代谢异常。 activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice.
已发布 PubMed:抗紧缩策略的arctigenin衍生物的合成和抗肿瘤评估。 Synthesis and antitumor evaluation of arctigenin derivatives based on antiausterity strategy.
已发布 PubMed:研究 Study on 的 human 肠 intestinal 细菌 bacterium blautia Blautia sp. AUH-JLD56 for the 转换 conversion of arctigenin to (-)-3'-des甲基杀伤员素 methylarctigenin.
已发布 PubMed: rp-hplc RP-hplc HPlc LC法测定大鼠血浆和脏器组织中Arctigenin的药代动力学。
已发布 PubMed:阿奇汀原减轻大鼠脂多糖诱导的急性肺损伤。 Arctigenin attenuates lipopolysaccharide-induced acute lung injury in rats.
已发布 PubMed:通过抑制酪氨酸酶表达来抑制果渣提取物中的arcingenin对黑素合成的抑制作用。 Inhibitory Effect of Arctigenin from Fructus Arctii Extract on Melanin Synthesis via Repression of Tyrosinase Expression.
已发布 PubMed:皂苷元诱导的针对 肝癌细胞系的特异性细胞毒性作用机理 Mechanism of Arctigenin-Induced Specific Cytotoxicity against Human Hepatocellular Carcinoma Cell Lines: 庚g2和smmc7721。 Hep G2 and SMMC7721.
已发布 PubMed:阿奇汀通过抑制橙花炎症来保护局灶性脑缺血再灌注大鼠。 Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation.
已发布 PubMed:黄花蒿从植物蒿的全部草药中获得的大头草草本油越南青蒿黄花草本油越南蒿青蒿洋甘菊草本油越南蒿草斯图瓦蒂草本油越南蒿木韦迪草本油越南精油。 Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithelial cells.
已发布 PubMed:箭毒苷及其脱甲基代谢产物与雌激素受体α的配体结合亲和力。 Ligand binding affinities of arctigenin and its demethylated metabolites to estrogen receptor alpha.
已发布 PubMed:arctigenin通过调节 胃癌细胞中细胞周期调节蛋白的表达来阻断rb的磷酸化,从而诱导细胞周期停滞。 Arctigenin induces cell cycle arrest by blocking the phosphorylation of Rb via the modulation of cell cycle regulatory proteins in human gastric cancer cells.
已发布 PubMed:通过抑制stat3信号通路,arctigenin可增强癌细胞对顺铂的化学敏感性。 Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway.
已发布 PubMed:从草本植物牛arc中分离到的Arctigenin的肿瘤特异性细胞毒性。 Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L.
已发布 PubMed:Arctigenin通过上调小鼠原代橙花元和 sh-sy5y橙花母细胞瘤细胞中p-creb的橙花保护作用。 Neuroprotective effect of arctigenin via upregulation of P-CREB in mouse primary neurons and human SH-SY5Y neuroblastoma cells.
已发布 PubMed:[Arctigenin的制备方法研究]。 [Research on the preparative method of Arctigenin].
已发布 PubMed:(-)-arctigenin作为抗癌药的先导化合物。 (-)-Arctigenin as a lead compound for anticancer agent.
已发布 PubMed:阿奇霉素对pma /离子霉素刺激的淋巴细胞活化的抑制作用。 Inhibitory effect of arctigenin on lymphocyte activation stimulated with PMA/ionomycin.
已发布 PubMed: 通过抑制jak-stat信号途径,arctigenin抑制了生的 raw264.7细胞中脂多糖诱导的inos表达。
已发布 PubMed:从牛蒡子的种子中分离出的arctigenin改善了小鼠的记忆障碍。 Arctigenin isolated from the seeds of Arctium lappa ameliorates memory deficits in mice.
已发布 PubMed:木酚素诱导的sw480细胞的凋亡和细胞核扩增 Cell and nuclear enlargement of SW480 cells induced by a plant lignan, arctigenin: 荧光显微镜和流式细胞仪评估细胞脱氧核糖核酸 DNA含量
已发布 PubMed:集成的化合物分析屏幕将线粒体电子传输链确定为天然产物马纳色汀的分子靶标 Integrated compound profiling screens identify the mitochondrial electron transport chain as the molecular target of the natural products manassantin, 倍半素 sesquicillin, 和arctigenin。 and arctigenin.
已发布 PubMed:樟脑木脂素archgenin与色氨酸降解酶吲哚胺2结合位点的相互作用 Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-双加氧酶。 3-dioxygenase.
已发布 PubMed:Arctigenin抑制未折叠的蛋白质反应,并使葡萄糖剥夺介导的癌细胞的细胞毒性敏感。 Arctigenin suppresses unfolded protein response and sensitizes glucose deprivation-mediated cytotoxicity of cancer cells.
已发布 PubMed:Arctigenin通过激活ampk减轻er压力。 Arctigenin alleviates ER stress via activating AMPK.
已发布 PubMed:--arctigenin衍生物的合成及其抗癌活性。 Synthesis of (-)-arctigenin derivatives and their anticancer activity.
已发布 PubMed:牛蒡苷元能有效提高久坐小鼠的跑步机耐力。 Arctigenin efficiently enhanced sedentary mice treadmill endurance.
已发布 PubMed:Arctigenin, 苯丙烷二苄基丁内酯木脂素 a phenylpropanoid dibenzylbutyrolactone lignan, 抑制i-iv型过敏性炎症和促炎酶。 inhibits type I-IV allergic inflammation and pro-inflammatory enzymes.
已发布 PubMed:葡萄糖缺乏的a549肿瘤细胞中4-氨基-4-脱羟基lartititinin衍生物的合成及细胞毒性评估 Synthesis and cytotoxicity evaluation of 4-amino-4-dehydroxylarctigenin derivatives in glucose-starved A549 tumor cells.
已发布 PubMed:来自牛蒡子的Arctigenin抑制 原代t淋巴细胞中白介素2和干扰素基因的表达。 Arctigenin from Arctium lappa inhibits interleukin-2 and interferon gene expression in primary human T lymphocytes.
已发布 PubMed:Arctigenin阻断未折叠的蛋白质反应,并显示出治疗性抗肿瘤活性。 Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
已发布 PubMed:Arctigenin的体外抗炎作用 In vitro anti-inflammatory effects of arctigenin, 来自牛蒡子的木脂素。 a lignan from Arctium lappa L., 通过抑制肌醇途径。 through inhibition on iNOS pathway.
已发布 PubMed: Arctii arctiin Arctii arctiin和arctigenin对感染了甲型流感 的免疫能力强和免疫功能低下的小鼠的治疗作用。
已发布 PubMed:Arctigenin治疗日本脑炎的新策略 Novel strategy for treatment of Japanese encephalitis using arctigenin, 植物木脂素。 a plant lignan.
已发布 PubMed:Arctigenin, 苯丙烷二苄基丁内酯木脂素 a phenylpropanoid dibenzylbutyrolactone lignan, 通过有效的mkk抑制来抑制map激酶和ap-1激活 inhibits MAP kinases and AP-1 activation via potent MKK inhibition: 在tnf-α抑制中的作用。 the role in TNF-alpha inhibition.
已发布 PubMed:基于新型可裂解mpeg-hz-chems聚合物阴道输送系统的ph和温度双敏感脂质体凝胶。 pH and temperature dual-sensitive liposome gel based on novel cleavable mPEG-Hz-CHEMS polymeric vaginal delivery system.
已发布 PubMed:牛蒡皂苷元通过与海藻酸盐受体结合,保护培养的皮质橙花元免受谷氨酸诱导的橙花变性。 Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor.
已发布 PubMed:牛蒡苷三甲基甲硅烷基衍生物的质量碎裂研究 Mass fragmentation study of the trimethylsilyl derivatives of arctiin, 松节苷 matairesinoside, arctigenin, 叶绿素 phylligenin, 苦参醇 matairesinol, 松脂醇和甲基arctigenin pinoresinol and methylarctigenin: 它们在植物提取物中的气相和液相色谱分析。 their gas and liquid chromatographic analysis in plant extracts.
已发布 PubMed:牛arc子的著名药用特性带来了新的期望。 New expectations from the well-known medicinal properties of Arctium lappa.
已发布 PubMed:连翘中arctigenin的抗炎活性。 Anti-inflammatory activity of arctigenin from Forsythiae Fructus.
已发布 PubMed:微乳电动色谱法分离fr果及其中草药制剂中的牛蒡苷和牛蒡苷元。 Microemulsion electrokinetic chromatography for the separation of arctiin and arctigenin in Fructus Arctii and its herbal preparations.
已发布 PubMed:Arctigenin的免疫调节作用 Immunomodulatory effect of arctigenin, 木脂素化合物 a lignan compound, 对肿瘤坏死因子-α和一氧化氮的产生 on tumour necrosis factor-alpha and nitric oxide production, 和淋巴细胞增殖。 and lymphocyte proliferation.
已发布 PubMed:Arctigenin抗流感 在体内的作用。 [Effect of anti-influenza virus of Arctigenin in vivo].
已发布 PubMed:来自大果果糖原的arctigenin是哺乳动物细胞中热休克反应的新型抑制剂。 Arctigenin from Fructus Arctii is a novel suppressor of heat shock response in mammalian cells.
已发布 PubMed:具有抗肿瘤药能力的抗肿瘤药arctigenin的鉴定。 Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation.
已发布 PubMed:反相高效液相色谱法测定fr果中的牛蒡苷和牛蒡苷元。 Determination of arctiin and arctigenin in Fructus Arctii by reverse-phase HPLC.
已发布 PubMed: 肠道细菌的分离与表征 Isolation and characterization of a human intestinal bacterium, 真细菌弧2 Eubacterium sp. ARC-2, 能够将Arctigenin脱甲基 capable of demethylating arctigenin, 在必要的代谢过程中进入肠内酯。 in the essential metabolic process to enterolactone.
已发布 PubMed: 通过离心分配色谱法从朝鲜连翘中制备分离和纯化arctigenin和苦参醇 matairesinol。
已发布 PubMed: 聚酰胺柱色谱结合hplc-esi / ms分离和鉴定牛arc(arctium lappa l。)叶片中的Arctii arctiin Arctii arctiin和arctigenin。
已发布 PubMed:基因改造的哺乳动物细胞系中天然木脂素(-)-arctigenin的自然转化,以表达单个细胞色素p450亚型。 Biotransformation of the naturally occurring lignan (-)-arctigenin in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms.
已发布 PubMed:红花中的木脂素通过吲哚胺2抑制色氨酸分解 Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-双加氧酶。 3-dioxygenase.
已发布 PubMed: 木脂素通过调节wnt /β-连环蛋白 β-catenin信号传导抑制细胞生长。
已发布 PubMed:Arctigenin诱导 白血病细胞凋亡及其作用机制 [Induction of apoptosis of the human leukemia cells by arctigenin and its mechanism of action].
已发布 PubMed:自由基介导的缀合物添加。对映体合成丁内酯天然产物 Free-radical-mediated conjugate additions. Enantioselective synthesis of butyrolactone natural products: (-)-内酯 (-)-enterolactone, (-)-arctigenin (-)-Arctigenin, (-)-异丁香配素 (-)-isoarctigenin, (-)-肾上腺酸 (-)-nephrosteranic acid, 和(-)-二十碳四烯酸。 and (-)-roccellaric acid.
已发布 PubMed:(-)-arctigenin作为 类免疫缺陷 1型整合酶抑制剂的先导结构。 (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase.
已发布 PubMed:来自牛蒡子的天然木脂素调节多药耐药癌细胞中的p-糖蛋白外排功能 Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells.
已发布 PubMed:木质素的自由基羧基化方法。 (-)-arctigenin的全合成 Radical carboxyarylation approach to lignans. Total synthesis of (-)-arctigenin, (-)-苦参醇 (-)-matairesinol, 及相关天然产品。 and related natural products.
已发布 PubMed:抗氧化剂 Antioxidants: 日本脑炎 感染的潜在抗 药物。 potential antiviral agents for Japanese encephalitis virus infection.
已发布 PubMed:刚果药用植物非洲蜜桃的抗菊苣成分。 Anti-austeritic Constituents of the Congolese Medicinal Plant Aframomum melegueta.
已发布 PubMed:雪莲种子中的三个新木脂素。 Three new lignans from the seeds of Saussurea involucrata.
已发布 PubMed:猕猴桃果实中二苄基丁内酯型木脂素的最佳产量 Optimum yields of dibenzylbutyrolactone-type lignans from Cynareae fruits, 在他们成熟的时候 during their ripening, 芽和酶促水解过程 germination and enzymatic hydrolysis processes, 通过在线色谱法测定。 determined by on-line chromatographic methods.
已发布 PubMed: hplc-uv和lc-ms在大鼠中血浆Arctii arctiin Arctii Arctiin及其主要代谢产物的药代动力学和组织分布。
已发布 PubMed:灰头草的植物化学特征和凋亡活性。 Phytochemical profile and apoptotic activity of Onopordum cynarocephalum.
已发布 PubMed:植物来源的抑制肿瘤生长的物质。 ii。阿替加宁-芥末的实验动物肿瘤药理学。 Tumour-growth inhibiting substances of plant origin. II. The experimental animal tumour-pharmacology of arctigenin-mustard.
已发布 PubMed:高效液相色谱/二极管阵列检测-电喷雾电离质谱法对生和加工的大果进行化学分析。 Chemical analysis of raw and processed Fructus arctii by high-performance liquid chromatography/diode array detection-electrospray ionization-mass spectrometry.
已发布 PubMed:Arctigenin: 来自牛蒡子的木脂素。 a lignan from Arctium lappa L.
已发布 PubMed:活性成分对气管菜从ifn-γ/ stat1和il-6 / stat3信号通路具有抑制活性。 Active components with inhibitory activities on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways from Caulis Trachelospermi.
已发布 PubMed:晚期胰腺癌的第一期研究的最新进展。在黑暗中狩猎? Update on phase I studies in advanced pancreatic adenocarcinoma. Hunting in darkness?
已发布 PubMed:维鲁西定的重新定位 Repositioning of Verrucosidin, 伴侣蛋白grp78的据称抑制剂 a purported inhibitor of chaperone protein GRP78, 作为线粒体电子传输链复合物的抑制剂。 as an inhibitor of mitochondrial electron transport chain complex I.
已发布 PubMed: hplc同时测定大鼠尿液和粪便中Arctii arctiin Arctii arctiin及其代谢物。
已发布 PubMed:阿魏谷类固醇酯。 Steroidal esters from Ferula sinkiangensis.
已发布 PubMed:从中药中寻找协同性支气管扩张剂和新型治疗慢性肺疾病的方法 Searching for synergistic bronchodilators and novel therapeutic regimens for chronic lung diseases from a traditional Chinese medicine, 青飞小燕湾。 Qingfei Xiaoyan Wan.
已发布 PubMed:来自牛蒡子的天然木脂素作为秀丽隐杆 的抗衰老剂。 Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans.
已发布 PubMed:超高效液相色谱与电喷雾电离串联质谱联用,并进行分级聚类分析,以评估印度洋ks(l。)c。一个。 MEY。来自不同的地理区域。 Ultra high performance liquid chromatography with electrospray ionization tandem mass spectrometry coupled with hierarchical cluster analysis to evaluate Wikstroemia indica (L.) C. A. Mey. from different geographical regions.
已发布 PubMed: dc DC水果中抗增殖木脂素的特异性水解和积累。
已发布 PubMed:响应面法优化大果加工工艺 Optimization of the processing technology of Fructus Arctii by response surface methodology.
已发布 PubMed:生弧酸 Arctigenic acid, 导致果糖降血糖活性的关键物质。 the key substance responsible for the hypoglycemic activity of Fructus Arctii.
已发布 PubMed:通过特殊工艺生产的松香热塑性季戊四醇酯,具有浅色的初始颜色和产品稳定性。 pexalyn 9100稳定的松香酯特别适合作为热熔胶和其他类型胶粘剂中具有成本效益的增粘树脂。它也可用作弹性体和蜡的树脂改性剂。 Pharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration of traditional Chinese medicine Flos Lonicerae Japonicae-Fructus Forsythiae herb couple by sequential negative and positive ionization ultra-high-performance liquid chromatography/tandem triple quadrupole mass spectrometric detection.
已发布 PubMed: Bardanae 水果 fructus(越子 goboshi)的细胞毒性成分。
已发布 PubMed:菊芋块茎中线粒体内转化酶活性和线粒体内膜相应的糖转运蛋白的证明。 Complementary fragmentation pattern analysis by gas chromatography-mass spectrometry and liquid chromatography tandem mass spectrometry confirmed the precious lignan content of Cirsium weeds.
已发布 PubMed:连翘叶中木脂素及其糖苷含量的季节性变化及相关生物合成酶的基因表达 Seasonal alteration in amounts of lignans and their glucosides and gene expression of the relevant biosynthetic enzymes in the Forsythia suspense leaf.
已发布 PubMed:差分脉冲极谱法测定复合材料中的n-甲基乙基黄酮氨基甲酸酯络合物在微晶萘或n-甲基乙基黄酮氨基甲酸酯-苄基二甲基十四烷基铵-萘吸附剂上的吸附量。 Dibenzylbutyrolactone lignans from Forsythia koreana fruits attenuate lipopolysaccharide-induced inducible nitric oxide synthetase and cyclooxygenase-2 expressions through activation of nuclear factor-κb and mitogen-activated protein kinase in RAW264.7 cells.
已发布 PubMed:牛fruit子果实中主要成分的测定。基质固相分散萃取结合hplc分离和荧光检测。 Determination of the major constituents in fruit of Arctium lappa L. by matrix solid-phase dispersion extraction coupled with HPLC separation and fluorescence detection.
已发布 PubMed:印度wikstroemia的新的瓜安型倍半萜烯。 New guaian-type sesquiterpene from Wikstroemia indica.
已发布 PubMed:在改性剂存在下,从二水合硫酸钙开始,按尺寸控制的方法制备α-半水合硫酸钙,以及在模拟体液中的溶解速率。 Simultaneous determination of five bioactive secolignans in rat plasma by LC-MS/MS for pharmacokinetic studies following oral administration of Peperomia dindygulensis Miq. extract.
已发布 PubMed: 生物测定指导的分离和鉴定金鱼(反对 against鱼)中中间果蝇(单基因)的活性成分。
已发布 PubMed:去甲二氢愈创木酸抑制作用 Inhibitory effect of nordihydroguaiaretic acid, 木质植物 a plant lignan, 蒙古沙鼠中幽门螺杆菌相关胃癌的发生 on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils.
已发布 PubMed:用网络药理学研究清肺消炎丸的抗炎机制。 [Anti-inflammatory mechanism of qingfei xiaoyan wan studied with network pharmacology].
已发布 PubMed:利用基于荧光偏振的高通量检测技术鉴定脂联素受体激动剂。 Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.
已发布 PubMed:牛arc种子中酚类成分的抗 活性。 Anti-austeric activity of phenolic constituents of seeds of Arctium lappa.
已发布 PubMed:连翘干果中新的金刚烷骨架诱导caspase-8和死亡受体的合成。 Induction of caspase-8 and death receptors by a new dammarane skeleton from the dried fruits of Forsythia koreana.
已发布 PubMed: 通过抑制i-kappabα alpha磷酸化和巨噬细胞中p65核易位,有效抑制二苄基丁内酯木脂素对脂多糖诱导型一氧化氮合酶表达的抑制作用。
已发布 PubMed:基于双生物活性的液相色谱-联用四极杆飞行时间质谱法对中药nf-κb抑制剂和β2ar激动剂的鉴定 Dual-bioactivity-based liquid chromatography-coupled quadrupole time-of-flight mass spectrometry for NF-κB inhibitors and β2AR agonists identification in Chinese Medicinal Preparation Qingfei Xiaoyan Wan.
已发布 PubMed:通过诱导细胞凋亡和ii期解毒酶来预防雪莲的化学预防作用。 The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme.
已发布 PubMed:保留离子的利尿剂2 Ion-sparing diuresis by 2, 3-二苯ylbut butane-1 ,4-二醇 4-diol, 合成的哺乳动物-木脂素衍生物。 a synthetic mammalian-lignan derivative.
已发布 PubMed:痕量气管茉莉中所含微量化学成分及结构鉴定 [Trace chemical constituents contained in Trachelospermum jasminoides and structure identification].
已发布 PubMed:连翘果实中的二苄基丁内酯木脂素对有意识的豚鼠对卵清蛋白激发的哮喘反应的抗哮喘作用。 Antiasthmatic action of dibenzylbutyrolactone lignans from fruits of Forsythia viridissima on asthmatic responses to ovalbumin challenge in conscious guinea-pigs.
已发布 PubMed:通过 类1型免疫缺陷 tat的细胞保护功能筛选出新型的pi3k / akt抑制剂。 Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat.
已发布 PubMed: 肠道菌群对 参皂苷rb1的代谢及其长双歧杆菌h-1的代谢β-d-葡萄糖苷酶的克隆 Metabolism of ginsenoside Rb1 by human intestinal microflora and cloning of its metabolizing β-D-glucosidase from Bifidobacterium longum H-1.
已发布 PubMed:生物活性指导的抗紫锥虫抗增殖化合物的分离。 Bioactivity-guided isolation of antiproliferative compounds from Centaurea arenaria.
已发布 PubMed: 天然木脂素的体外抗艾滋病 HIV活性差异。
已发布 PubMed:牛arc子根提取物的抗氧化和体外抗增殖活性。 Antioxidative and in vitro antiproliferative activity of Arctium lappa root extracts.
已发布 PubMed:灰担子菌发酵的弓形果的生物活性。 Biological activities of Fructus arctii fermented with the basidiomycete Grifola frondosa.
已发布 PubMed:[不同厂家生产的维他命C银翘片的质量比较研究]。 [A comparative research on quality of Vitmin C Yinqiao tablets from different manufacturers].
已发布 PubMed:牛arc种子中木脂素代谢化学的动力学研究。 [Dyuamical studies on metabolic chemistry of lignans from seeds of Arctium lappa].
已发布 PubMed: [运动会conopsea conopsea的组成部分]。
已发布 PubMed:雌激素受体β结合对乳腺皮质及其成分的影响 Evaluation of estrogen receptor Beta binding of pruni cortex and its constituents.
已发布 PubMed:梯度增强核的豪沃斯效应光谱法在植物次生代谢产物的结构解析中的应用 Application of gradient-enhanced nuclear Overhauser effect spectroscopy GOESY) in the structure elucidation of plant secondary metabolites.
已发布 PubMed:番薯番木瓜的细胞毒活性。 Cytotoxic activity of Ipomoea cairica.
已发布 PubMed: ce-ms分析显示,现代和旧的意大利软小麦(triticum aestivum l。)品种种子中的木脂素概况。
已发布 PubMed:牛arc中丁内酯木脂素对白血病细胞的抗增殖和凋亡作用。 Antiproliferative and apoptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells.
已发布 PubMed:乌龟的肝保护性二苄基丁内酯木脂素抗ccl4诱导的原代培养大鼠肝细胞毒性。 Hepatoprotective dibenzylbutyrolactone lignans of Torreya nucifera against CCl4-induced toxicity in primary cultured rat hepatocytes.
已发布 PubMed:植物木脂素的体外代谢 In vitro metabolism of plant lignans: 哺乳动物木脂素肠内酯和肠二醇的新前体。 new precursors of mammalian lignans enterolactone and enterodiol.
已发布 PubMed:天然类黄酮和木脂素是有效的抗 白血病hl-60细胞的细胞抑制剂。 Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.
已发布 PubMed:印度北部频繁爆发日本脑炎的预防策略。 Preventive strategies for frequent outbreaks of Japanese encephalitis in Northern India.
已发布 PubMed:美洲菊 Americanin, 具有生物活性的二苄基丁内酯木脂素 a bioactive dibenzylbutyrolactone lignan, 来自美洲百日草的种子。 from the seeds of Centaurea americana.
已发布 PubMed:天然存在的木脂素有效诱导大肠肿瘤细胞凋亡。 Naturally occurring lignans efficiently induce apoptosis in colorectal tumor cells.
已发布 PubMed:箭尾草的倍半萜内酯。 Sesquiterpene lactones from Centaurea tweediei.
已发布 PubMed:萨维宁 Savinin, 檀木罗汉果的木脂素抑制肿瘤坏死因子-α的产生和t细胞增殖。 a lignan from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T cell proliferation.
已发布 PubMed:分化诱导剂的研究。 vi。来自牛蒡的木脂素衍生物。 (2)。 Studies on differentiation inducers. VI. Lignan derivatives from Arctium fructus. (2).
已发布 PubMed:[化学成分的气管茉莉(lindl。)lem。变种太子参]。 [Chemical components of Trachelospelmun jasminoides (Lindl.) Lem. var. heterophyllum Tsiang].
已发布 PubMed:木脂素化合物在大鼠胃肠道中的结构转化。 Structural transformation of lignan compounds in rat gastrointestinal tract.
已发布 PubMed: 木脂体和百日草头颅 sphaerocephala ssp的其他成分。多糖。
已发布 PubMed: 来自fasara 特斯曼尼 tessmannii(芸香科)茎皮的α-葡萄糖苷酶抑制性五环三萜。
已发布 PubMed:评估 类对木脂素及其代谢产物的接触。 Assessing exposure to lignans and their metabolites in humans.
已发布 PubMed:圆锥形雪莲中的木脂素及其无生产抑制活性。 Lignans from Saussurea conica and their NO production suppressing activity.
已发布 PubMed:木炭在整株植物中的木脂素研究和樟脑的细胞悬浮培养。 A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris.
已发布 PubMed:肠细菌将arctin转化为雌激素和抗雌激素物质。 Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
已发布 PubMed:牛膝木脂素生物合成中的立体化学多样性。 Stereochemical diversity in lignan biosynthesis of Arctium lappa L.
已发布 PubMed:香to的橙花保护性二苄基丁内酯木脂素。 Neuroprotective dibenzylbutyrolactone lignans of Torreya nucifera.
已发布 PubMed:card豆小的arctinin和opopordopicrin。小扁豆。 Arctiin and onopordopicrin from Carduus micropterus ssp. perspinosus.
已发布 PubMed:水母雪莲地上部分木脂素的抗肿瘤活性。 Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
已发布 PubMed:植物来源的领先化合物,可用于化学疗法治疗 类免疫缺陷 (hiv)感染。 Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection.
已发布 PubMed:埃及百日草属的组成。 iii。地上部分的酚类成分。 Constituents of the Egyptian Centaurea scoparia. III. Phenolic constituents of the aerial parts.
已发布 PubMed:[关于牛arc的化学成分的研究]。 [Studies on the chemical constituents of Arctium lappa L].
已发布 PubMed: 对花椒zansoxylum 特斯曼尼 tessmannii1的植物化学的贡献。
 
笔记 Notes:
前体 precursor to 儿茶酚 catechols; in 许多 many plants. 异酚 Isol. from 中国 Cnicus benedictus, 连翘 forsythia viridissima, 牛子 Arctium lappa, 番薯 ipomoea cairica等(ccd CCD) arctigenin是在菊科的某些植物中发现的木脂素 Arctigenin is a lignan found in certain plants of the Asteraceae , 包括更大的牛d(arctium lappa)和雪莲。它具有抗 和抗癌作用。它是牛蒡苷的糖苷配基。 (维基百科) including the Greater burdock (Arctium lappa) and Saussurea heteromalla. It has shown antiviral and anticancer effects. It is the aglycone of arctiin. (Wikipedia)
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