dihydroquercetin
黄酮 flavone, 2,3-二氢-3 3-dihydro-3,3',4',5,7-五羟基 7-pentahydroxy-

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    480-18-2滑石粉> 98% 480-18-2 Taxifolin >98%
    滑石粉是许多植物(如红豆杉)中的类黄酮 Taxifolin is a flavonoid in many plants such as Taxus chinensis, 西伯利亚落叶松 Siberian larch, 雪松deodara deodara等。紫杉醇已显示出以剂量依赖性方式抑制 癌细胞的生长。
Name:(2r)-2-(3 (2R)-2-(3,4-二羟基苯基)-3 4-dihydroxyphenyl)-3,5,7-三羟基-2 7-trihydroxy-2,3-二氢铬-4-酮 3-dihydrochromen-4-one
CAS号 CAS Number: 480-18-2Picture of molecule3D/INCHI
其他 Other:17654-26-1
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:207-543-4
FDA UNII:9SOB9E3987
nikkaji网站 Nikkaji Web:J727.680J
贝尔斯坦数 Beilstein Number:0093548
MDL :mfcd00006845 MFCD00006845
XlogP3-AA:1.50(est) 1.50 (est)
分子量 Molecular Weight:304.25504000
式 Formula:c15 h12 o7 C15 H12 O7
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:antioxidants
 
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谷歌学术 Google Scholar:搜索 Search
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dg sante食品添加剂 DG SANTE Food Additives:dihydroquercetin
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
沸点 Boiling Point: 687.60 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 508.00 °F. tcc TCC ( 264.20 °C. ) (est)
logp(o / w) logP (o/w): 0.950
溶于 Soluble in:
 水 water, 2.203e + 004 mg / l @ 25°c(est) 2.203e+004 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: antioxidants
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
滑石粉> 98% Taxifolin >98%
气味 Odor: characteristic
采用 Use: 滑石粉是许多植物(如红豆杉)中的类黄酮 Taxifolin is a flavonoid in many plants such as Taxus chinensis, 西伯利亚落叶松 Siberian larch, 雪松deodara deodara等。紫杉醇已显示出以剂量依赖性方式抑制 癌细胞的生长。
p.l.托马斯 P.L. Thomas
二氢槲皮素 Dihydroquercetin
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
(±)-紫杉醇≥90% (±)-Taxifolin ≥90%
西格玛·奥尔德里奇 Sigma-Aldrich
仅供实验/研究使用。 For experimental / research use only.
二氢槲皮素 Dihydroquercetin
分析analytical standard
 
安全信息 Safety Information:
首选sds SDS : 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
腹腔内小鼠 intraperitoneal-mouse LD50 985 mg/kg
Russian 药理 Pharmacology and Toxicology 卷 Vol. 38, pg。 213 Pg. 213, 1975.

腹膜内大鼠 intraperitoneal-rat LD50 1200 mg/kg
Japanese 日志 Journal of 药理 Pharmacology. 卷 Vol. 21, pg。 377 Pg. 377, 1971.

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: antioxidants
推荐的双氢槲皮素使用量最高为 Recommendation for dihydroquercetin usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐的双氢槲皮素风味剂使用量最高为 Recommendation for dihydroquercetin flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
欧洲食品安全局(efsa EFSA)参考 :

科学的 Scientific 意见 Opinion on 富含滑石粉 taxifolin-rich extract from dahurian Dahurian 落叶松 Larch (落叶松 Larix gmelinii gmelinii)
视图 View page or 视图 View pdf

声明 Statement on the 安全 safety of 富含滑石粉 taxifolin-rich extract from dahurian Dahurian 落叶松 Larch (落叶松 Larix gmelinii gmelinii)
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
EPA物质注册服务(tsca TSCA) :480-18-2
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :10185
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
(2r)-2-(3 (2R)-2-(3,4-二羟基苯基)-3 4-dihydroxyphenyl)-3,5,7-三羟基-2 7-trihydroxy-2,3-二氢铬-4-酮 3-dihydrochromen-4-one
chemidplus Chemidplus:0000480182
 
参考资料 References:
 (2r)-2-(3 (2R)-2-(3,4-二羟基苯基)-3 4-dihydroxyphenyl)-3,5,7-三羟基-2 7-trihydroxy-2,3-二氢铬-4-酮 3-dihydrochromen-4-one
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):10185
pubchem(sid) Pubchem (sid):134974339
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
食物 FooDB:FDB002749
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 樱桃酸樱桃植物 cherry sour cherry plant
搜索 Search Trop Picture
 牛至叶 oregano leaf
搜索 Search Trop Picture
 茶 tea
搜索 Search Trop Picture
 百里香 thyme
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同义词 Synonyms:
4H-1-benzopyran-4-one, 2-(3,4-二羟基苯基)-2 4-dihydroxyphenyl)-2,3-二氢-3 3-dihydro-3,5,7-三羟基 7-trihydroxy-
4H-1-benzopyran-4-one, 2-(3,4-二羟基苯基)-2 4-dihydroxyphenyl)-2,3-二氢-3 3-dihydro-3,5,7-三羟基 7-trihydroxy-, (2R,3R)-
4H-1-benzopyran-4-one, 2-(3,4-二羟基苯基)-2 4-dihydroxyphenyl)-2,3-二氢-3 3-dihydro-3,5,7-三羟基 7-trihydroxy-, (2R)-
(2R,3R)-dihydroquercetin
(2R-trans)-2-(3,4-dihydroxyphenyl)-2,3-二氢-3 3-dihydro-3,5,7-三羟基 7-trihydroxy-4-benzopyrone
(2r)-2-(3 (2R)-2-(3,4-dihydroxyphenyl)-3,5,7-三羟基-2 7-trihydroxy-2,3-二氢 dihydro-4H-铬 chromen-4-one
(2r)-2-(3 (2R)-2-(3,4-dihydroxyphenyl)-3,5,7-三羟基-2 7-trihydroxy-2,3-二氢铬-4-酮 3-dihydrochromen-4-one
 黄烷酮 flavanone, 3,3',4',5,7-五羟基 7-pentahydroxy-
 黄酮 flavone, 2,3-二氢-3 3-dihydro-3,3',4',5,7-五羟基 7-pentahydroxy-
3,3',4',5,7-pentahydroxy黄烷酮 flavanone
 quercetin, 二氢 dihydro-
 taxifolin
 紫杉醇 taxifoliol
 

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已发布 PubMed:种植物多酚对膀胱癌原联苯胺诱导的致突变性的影响。 Effects of various plant polyphenols on bladder carcinogen benzidine-induced mutagenicity.
已发布 PubMed:橄榄树的小树枝 Small branches of olive tree: 与橄榄叶互补的生物酚来源。 a source of biophenols complementary to olive leaves.
已发布 PubMed: 从阿尔佩鲁霍 alperujo(橄榄油工业的半固体残渣)中静态静态过热液体萃取羟基酪醇和其他生物酚。
已发布 PubMed:hplc串联质谱法表征 体内白藜芦醇的代谢。 HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humans.
已发布 PubMed:新型过表达水稻花色素苷合酶的转基因水稻积累了类黄酮的混合物,导致抗氧化能力增强。 Novel transgenic rice overexpressing anthocyanidin synthase accumulates a mixture of flavonoids leading to an increased antioxidant potential.
已发布 PubMed:冷冻干燥的亚马逊棕榈浆果的植物化学和营养成分 Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, 阿萨伊果、巴西莓市场。 (巴西莓 acai)。
已发布 PubMed:黄酮类化合物介导的2-氨基-1-甲基-6-苯基咪唑的转运的体外和计算机模拟研究[4] An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]吡啶(phip)通过caco-2单层。 5-b]pyridine (PhIP) through Caco-2 monolayers.
已发布 PubMed:新构建的稳定的报告基因细胞系,用于亲电反应元件介导的基因表达的机理研究,揭示了类黄酮平面性的作用。 Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.
已发布 PubMed: 罗望子(tamarindus indica l。)种子和果皮中酚类抗氧化剂的分离和结构解析。
已发布 PubMed:对茶多酚自由基清除能力和抗氧化活性的影响 Effects of structure on radical-scavenging abilities and antioxidative activities of tea polyphenols: 使用1的核磁共振 NMR分析方法 ,1-二苯基-2-吡啶并肼基。 1-diphenyl-2-picrylhydrazyl radicals.
已发布 PubMed:红洋葱鳞茎的解痉皂苷 Antispasmodic saponins from bulbs of red onion, 葱属变种特罗佩阿。 Allium cepa L. var. Tropea.
已发布 PubMed:类黄酮诱导癌细胞凋亡与其抑制脂肪酸合酶活性的能力有关。 Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity.
已发布 PubMed:水飞蓟素的影响 Effects of silymarin, 天然的肝脏保护剂 a natural hepatoprotector, 在围产期奶牛中。 in periparturient dairy cows.
已发布 PubMed:类黄酮与稳定自由基反应的动力学研究。 Kinetic study of flavonoid reactions with stable radicals.
已发布 PubMed: 黄酮对十字花科害虫mamestra 配置 configurata walker的取食和发育的影响。
已发布 PubMed:黄酮介导的mcf7乳腺癌细胞中谷胱甘肽s-转移酶p1-1和gs-x泵浦活性的结构要求。 Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
已发布 PubMed:选定树种的结节木提取物和酚类化合物的抗氧化活性。 Antioxidant activity of knotwood extractives and phenolic compounds of selected tree species.
已发布 PubMed:植物类黄酮和酚酸对花生四烯酸乙酯丙二醛形成的抑制作用 Inhibitory effects of plant-derived flavonoids and phenolic acids on malonaldehyde formation from ethyl arachidonate.
已发布 PubMed:辣根过氧化物酶和过氧化氢使槲皮素诱导的肌酸激酶失活。槲皮素的促氧化和抗氧化作用。 Inactivation of creatine kinase induced by quercetin with horseradish peroxidase and hydrogen peroxide. pro-oxidative and anti-oxidative actions of quercetin.
已发布 PubMed:红和白葡萄品种酿造的起泡酒陈化过程中低分子量酚类化合物的研究。 Study of low molecular weight phenolic compounds during the aging of sparkling wines manufactured with red and white grape varieties.
已发布 PubMed:在二氢黄酮醇还原酶基因座上,控制芸苔属的种皮和幼苗叶片中的色素沉着受到控制。 Pigmentation in the developing seed coat and seedling leaves of Brassica carinata is controlled at the dihydroflavonol reductase locus.
已发布 PubMed:电子自旋共振光谱法对黄酮类化合物抗氧化活性的动力学和化学计量评估。 Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy.
已发布 PubMed:儿茶素和其他类黄酮的结构依赖性植物毒性 Structure-dependent phytotoxicity of catechins and other flavonoids: 黄cent(无花斑的矢车菊)根的无细胞蛋白质提取物进行类黄酮转化。 flavonoid conversions by cell-free protein extracts of Centaurea maculosa (spotted knapweed) roots.
已发布 PubMed:新型苯甲酸酯的分离与表征 Isolation and characterization of novel benzoates, 肉桂 cinnamates, 类黄酮 flavonoids, 和 酒中的木脂素,并筛选抗氧化活性。 and lignans from Riesling wine and screening for antioxidant activity.
已发布 PubMed:葡萄茎中的酚类成分。 Phenolic composition of grape stems.
已发布 PubMed:苯氧基自由基再生酚类抗氧化剂 Regeneration of phenolic antioxidants from phenoxyl radicals: esr和抗氧化剂等级的电化学研究。 an ESR and electrochemical study of antioxidant hierarchy.
已发布 PubMed:食品成分会减弱c6星形胶质细胞中的单胺氧化酶活性和过氧化物水平。 Food constituents attenuate monoamine oxidase activity and peroxide levels in C6 astrocyte cells.
已发布 PubMed:各种饮食化合物在体外减弱c6星形胶质细胞培养物中一氧化氮生成的作用。 In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds.
已发布 PubMed:大鼠肝微粒体对类黄酮的体外生物转化。 In vitro biotransformation of flavonoids by rat liver microsomes.
已发布 PubMed:黄酮醇槲皮素 The flavonols quercetin, dna溶液中的芦丁和茉莉 rutin and morin in DNA solution: 紫外可见二向色(和中红外)分析说明了生物聚合物与亲核植物染料之间的可能联系。 UV-vis dichroic (and mid-infrared) analysis explain the possible association between the biopolymer and a nucleophilic vegetable-dye.
已发布 PubMed:[二氢槲皮素-一种新的抗氧化剂和具有生物活性的食品添加剂]。 [Dihydroquercetin--a new antioxidant and biologically active food additive].
已发布 PubMed:[天然黄酮作为膳食抗氧化剂和生物活性添加剂]。 [Natural flavonoids as dietary antioxidants and biologically active additives].
已发布 PubMed:黄酮类化合物抑制活性氧诱导的细胞毒性。 Suppression of active oxygen-induced cytotoxicity by flavonoids.
 
笔记 Notes:
黄酮醇和黄烷木质素之间的关键中间体。 a key intermediate between flavonols and flavanolignins.
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