乳链菌肽 nisin A
新星 novasin

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  • American International Chemical, LLC.
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    1414-45-5乳链菌肽3% 1414-45-5 Nisin 3%
  • Glentham Life Sciences
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    青岛保税区联合国际贸易有限公司 Qingdao Free Trade Zone United International Trade Co., 公司成立于1996年 Ltd.was founded in 1996, 香基/香型从事食品添加剂的生产和进出口 specializing in the production and import and export of food additives,调味原料和医药化工原料。公司拥有经验丰富的研发和业务 员 flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,产品质量 product quality, 低价 low price, 高效的服务和快速的洞察力,并掌握最新的市场信息。 efficient service and fast insight and grasp the latest market information.
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    7181N Nisin nat Nat。
CAS号 CAS Number: 1414-45-5Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:215-807-5
FDA UNII:EN8XKG133D
MDL :mfcd00131724 MFCD00131724
XlogP3-AA:-6.10(est) -6.10 (est)
分子量 Molecular Weight:3354.12550000
式 Formula:c143 h230 n42 o37 s7 C143 H230 N42 O37 S7
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:antimicrobial agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 FDA/DG SANTE Petitions, 评论 Reviews, 告示 Notices:
GRN 65 Nisin 视图 View - notice pdf格式 PDF
欧洲联盟 EU 桑科 SANCO Nisin 视图 View - 评论 review
食品添加剂 JECFA Food Additive: Nisin
gsfa 法典 Codex : 乳链菌肽(234) Nisin (234)
dg sante食品添加剂 DG SANTE Food Additives:乳链菌肽 nisin A
fda mainterm(satf) FDA Mainterm (SATF):977127-33-5 ; NISIN PREPARATION
自由贸易区法规 FDA Regulation:
自由贸易区 FDA PART 133 -- 起司 起司 CHEESES and AND 有关 RELATED 起司 CHEESE PRODUCTS
Subpart b--要求 B--要求 需求 Requirements for 浸膏 Specific 标准化的 Standardized 起司 Cheese and 有关 Related 产品展示 Products
Sec. 133.179 巴氏杀菌 Pasteurized 处理 process 起司 cheese 传播 spread.


自由贸易区 FDA PART 184 -- 直接 DIRECT FOOD 物质 SUBSTANCES 肯定的 AFFIRMED AS 通常 GENERALLY 公认的 RECOGNIZED AS SAFE
Subpart b--列出 B--清单 Listing of 浸膏 Specific Substances 肯定的 Affirmed as GRAS
Sec. 184.1538 Nisin 制备 preparation.
 
物理性质 Physical Properties:
出现 Appearance:白ti浅褐色粉末(est) white ti pale brown powder (est)
食品化学品法典列表 Food Chemicals Codex Listed: No
闪点 Flash Point: 32.00 °F. tcc TCC ( 0.00 °C. ) (est)
溶于 Soluble in:
 水 water
不溶于 Insoluble in:
 非极性溶剂 non-polar solvents
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: antimicrobial agents
 
供应商 Suppliers:
American International Chemical, LLC.
Nisin
安徽海北 Anhui Haibei
乳酸链球菌的乳链菌肽 Nisin From Streptococcus Lactis
安徽海北 Anhui Haibei
Nisin
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
乳链菌肽3% Nisin 3%
食品化学国际 Foodchem International
Nisin
Glentham Life Sciences
Nisin
格雷厄姆化学 Graham Chemical
Nisin
Jiangyin Healthway
Nisin
新功能食品成分 New functional food ingredients
Penta International
NISIN
普里诺娃 Prinova
Nisin
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
乳酸乳球菌中的乳链菌肽 Nisin from Lactococcus lactis
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
乳酸乳球菌产生的乳链菌肽2.5%(剩余氯化钠和变性乳固体) Nisin from Lactococcus lactis 2.5% (balance sodium chloride and denatured milk solids)
中诺食品配料 Sinofi Food Ingredients
Nisin
气味 Odor: characteristic
采用 Use: 防腐剂 Preservative, 化妆品 Cosmetics, 抗菌的 Antibacterial, 培根 Bacon, 起司 Cheese, 罐头食品 Canned Food, 曲奇饼 Cookie, 汽水 Soft Drink, 肉 Meat, 奶制品 Dairy Product, 造黄油 Margarine, 海鲜 Sea Food, 蛋制品 Egg Products, 果汁 Fruit Juice, 酱料 Sauces, 烘烤食物 Baking Food, 秋刀鱼 Sauage, 啤酒 Beer, 葡萄酒 Wine, 调味剂。 Flavoring Agent.
天津 才化工 Tianjin Talent Chemical
Nisin
United International
尼辛纳特 Nisin Nat.
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
静脉老鼠 intravenous-mouse LD50 100 mg/kg
"crc CRC 手册 Handbook of 抗生素 Antibiotic 化合物 Compounds," 第1卷 Vols.1- , 伯迪 Berdy, j. J., 博卡·拉顿 Boca Raton, FL, crc新闻 CRC Press, 1980年4(2) 1980Vol. 4(2), pg。 228 Pg. 228, 1980.

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
antimicrobial agents
推荐用于乳链菌肽的使用水平最高为 Recommendation for nisin A usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐用于乳链菌肽的调味剂用量最高可达 Recommendation for nisin A flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
欧洲食品安全局(efsa EFSA)参考 :

食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 flavourings, 处理中 处理 processing 艾滋病 aids and 材料 materials in contact with food (afc AFC) 有关 related to the safety in use of nisin as a food additive in an 额外 additional 类别 category of 液体 liquid eggs
视图 View page or 视图 View pdf

食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 flavourings, 处理中 处理 processing 艾滋病 aids and 材料 materials in contact with food (afc AFC) 有关 related to The use of nisin (E 234) as a food additive
视图 View page or 视图 View pdf

安全 Safety of nisin (E 234) as a food additive in the 光 light of new 毒理学的 toxicological data and the 提议的 proposed 延期 extension of use
视图 View page or 视图 View pdf

辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :16129667
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
chemidplus Chemidplus:0001414455
 
参考资料 References:
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:1414-45-5
pubchem(cid) Pubchem (cid):16129667
pubchem(sid) Pubchem (sid):134978871
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
食物 FooDB:FDB002386
fda食品添加剂状况清单 FDA Listing of Food Additive Status:视图 View
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and 核心组件 core components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 微花园 microgard 毫克 MG 300
 尼沙普林 nisaplin
 nisin 制备 preparation
 尼西特罗 nisitrol
 新星 novasin
 

文章 Articles:

已发布 PubMed:乳链菌肽α和乳链菌肽v半纯化制剂单独使用以及与植物精油联合使用可控制单核细胞增生性李斯特菌的功效。 Efficacy of nisin A and nisin V semi-purified preparations alone and in combination with plant essential oils to control Listeria monocytogenes.
已发布 PubMed:液相色谱-串联质谱法测定牛奶中乳酸链球菌素a和乳酸链球菌素z的方法 Analysis method for determination of nisin A and nisin Z in cow milk by using liquid chromatography-tandem mass spectrometry.
已发布 PubMed:表面糖胺聚糖保护真核细胞免受膜驱动的肽细菌素的侵害。 Surface glycosaminoglycans protect eukaryotic cells against membrane-driven peptide bacteriocins.
已发布 PubMed:金黄熊果在培养液中的行为 Behavior of Staphylococcus aureus in culture broth, 在原料和热牛奶中 in raw and thermized milk, 在存在或不存在乳酸乳球菌亚种的情况下,在加工和储存传统希腊格拉维拉干酪的过程中。 creemoris m104 and during processing and storage of traditional Greek Graviera cheese in the presence or absence of Lactococcus lactis subsp. cremoris M104, 荒野 a wild, 新型乳链菌肽生产原料乳分离物。 novel nisin A-producing raw milk isolate.
已发布 PubMed:除了乳酸乳球菌亚种的热牛奶。 creemoris m104 Addition to thermized milk of Lactococcus lactis subsp. cremoris M104, 荒野 a wild, 新型乳链菌肽A产生菌株 novel nisin a-producing strain, 替代了因热化作用而降低的本地生乳微生物菌群的天然抗李斯特菌活性。 replaces the natural antilisterial activity of the autochthonous raw milk microbiota reduced by thermization.
已发布 PubMed:bovicin hc5和nisin减少了金黄熊果对聚苯乙烯的粘附,并改变了疏水性和粘附的吉布斯自由能。 Bovicin HC5 and nisin reduce Staphylococcus aureus adhesion to polystyrene and change the hydrophobicity profile and Gibbs free energy of adhesion.
已发布 PubMed:乳链菌肽抑制火腿中乳酸菌的生长 Growth inhibition of lactic acid bacteria in ham by nisin: 一种模型方法。 a model approach.
已发布 PubMed:抗菌肽乳链菌肽 Antibacterial peptide nisin: 在抑制口腔致病菌方面有潜在作用。 a potential role in the inhibition of oral pathogenic bacteria.
已发布 PubMed:-β-内酰胺类抗生素对肠炎歐洲海濱草血清型 的临床评价 Evaluation of nisin-β-lactam antibiotics against clinical strains of Salmonella enterica serovar Typhi.
已发布 PubMed:那他霉素的作用 Effect of natamycin, 乳链菌肽和甘油对理化性质的影响 nisin and glycerol on the physicochemical properties, 木薯淀粉可食用膜的粗糙度和疏水性。 roughness and hydrophobicity of tapioca starch edible films.
已发布 PubMed:菌素收获的乳链菌肽生物合成途径的克隆和优化。 Cloning and optimization of a nisin biosynthesis pathway for bacteriocin harvest.
已发布 PubMed:优化杀菌和抑菌治疗相结合的方法,以控制冷熏鲑鱼的单核细胞增生李斯特菌。 Optimization of combinations of bactericidal and bacteriostatic treatments to control Listeria monocytogenes on cold-smoked salmon.
已发布 PubMed:最小抑菌浓度水平的管内冲洗剂mtad与乳链菌肽联合对肠球菌球菌生长和致病基因表达的影响 Effects of intracanal irrigant MTAD Combined with nisin at sub-minimum inhibitory concentration levels on Enterococcus faecalis growth and the expression of pathogenic genes.
已发布 PubMed:商业天然抗菌剂单独使用或与病原菌和腐败菌结合使用的功效。 Efficacy of commercial natural antimicrobials alone and in combinations against pathogenic and spoilage microorganisms.
已发布 PubMed:乳链菌肽A可延长高脂冷藏乳制品甜点的保质期 Nisin A extends the shelf life of high-fat chilled dairy dessert, 牛奶布丁。 a milk-based pudding.
已发布 PubMed:通过压力处理灭活黄瓜汁中天然存在的微生物。 Inactivation of naturally occurring microbiota in cucumber juice by pressure treatment.
已发布 PubMed:乳酸小球菌ul5和乳酸乳球菌atcc 11454能够在模拟胃肠道条件下生存并表达其细菌素基因。 Pediococcus acidilactici UL5 and Lactococcus lactis ATCC 11454 are able to survive and express their bacteriocin genes under simulated gastrointestinal conditions.
已发布 PubMed:乳链菌肽铰链的密集诱变导致增强衍生物的合理设计。 Intensive mutagenesis of the nisin hinge leads to the rational design of enhanced derivatives.
已发布 PubMed:胡椒提取物和乳链菌肽对酸脂环酸杆菌的抗菌活性的评价。 Evaluation of the antibacterial activity of Piperaceae extracts and nisin on Alicyclobacillus acidoterrestris.
已发布 PubMed:mb SmbFT, 假定的abc转运蛋白复合体 a putative ABC transporter complex, 可以针对链球菌中的羊毛硫抗生素smb提供保护。 confers protection against the lantibiotic Smb in Streptococci.
已发布 PubMed:乳链菌肽和/或那他霉素改善盖洛提里奶酪的货架期的功效。 Efficacy of nisin and/or natamycin to improve the shelf-life of Galotyri cheese.
已发布 PubMed:菌素对耐甲氧西林金黄熊果生物膜的影响 Effects of bacteriocins on methicillin-resistant Staphylococcus aureus biofilm.
已发布 PubMed:溶血素的表达和递送以抵抗产气荚膜梭菌。 Expression and delivery of an endolysin to combat Clostridium perfringens.
已发布 PubMed:对I类细菌素的抗性涉及三个不同的两组分系统 Three distinct two-component systems are involved in resistance to the class I bacteriocins, 努卡辛isk-1和乳链菌肽 Nukacin ISK-1 and nisin A, 在金黄熊果中。 in Staphylococcus aureus.
已发布 PubMed: 新型的双组分nsrrs和lcrrs系统参与了变形链球菌中针对乳酸链球菌素a和核蛋白 Nukacin isk-1的独特抗性途径。
已发布 PubMed:齐雷克斯 Zirex: 乳酸菌的新型锌调节表达系统。 a novel zinc-regulated expression system for Lactococcus lactis.
已发布 PubMed:乳酸菌中新型细菌素的筛选和表征。 Screening and characterization of novel bacteriocins from lactic acid bacteria.
已发布 PubMed:乳链菌肽在亲水和疏水表面上的吸附 Nisin adsorption on hydrophilic and hydrophobic surfaces: 相互作用和抗菌活性的证据。 evidence of its interactions and antibacterial activity.
已发布 PubMed:大肠菌素和细菌素在控制革兰氏阴性病原体之间的协同作用及其降低哺乳动物上皮细胞抗生素毒性的潜力。 Synergistic effect between colistin and bacteriocins in controlling Gram-negative pathogens and their potential to reduce antibiotic toxicity in mammalian epithelial cells.
已发布 PubMed:野性的表征 Characterization of a wild, 新的产生乳链菌肽α的乳球菌菌株。乳酸亚种鸡骨草 cremoris基因型和一个。乳酸亚种乳酸表型 , 从希腊原料牛奶中分离。 isolated from Greek raw milk.
已发布 PubMed:赖氨酸12的饱和诱变导致鉴定出具有增强的抗菌活性的乳链菌肽a的衍生物。 Saturation mutagenesis of lysine 12 leads to the identification of derivatives of nisin A with enhanced antimicrobial activity.
已发布 PubMed:枯草芽孢杆菌中融合了相扑素的乳酸菌素q的分泌表达。 Secretory expression of lacticin Q fused with SUMO in Bacillus subtilis.
已发布 PubMed: 乳链菌肽A和乳链菌肽v V对小鼠单核细胞增生李斯特菌的体内活性。
已发布 PubMed:[由乳酸乳球菌亚种产生的细菌素的特性和鉴定。乳酸194-k]。 [Characteristics and identification of bacteriocins produced by Lactococcus lactis subsp. lactis 194-K].
已发布 PubMed:[过表达乳链菌肽结构基因nisa对乳链菌肽产生的影响]。 [Effect of overexpressing Nisin A structural gene nisA on Nisin A production].
已发布 PubMed:成长 Growth, 益生菌候选物在模拟结肠条件下产生酸和细菌素。 acid production and bacteriocin production by probiotic candidates under simulated colonic conditions.
已发布 PubMed:生物工程化的乳酸链球菌素衍生物,对革兰氏阳性和革兰氏阴性病原体均具有增强的活性。 Bioengineered nisin A derivatives with enhanced activity against both Gram positive and Gram negative pathogens.
已发布 PubMed:枯草芽孢杆菌对羊毛硫抗生素的蛋白质组反应反映了与细胞质膜相互作用的差异。 Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane.
已发布 PubMed:【乳酸菌的抗菌代谢物 [Antibacterial metabolites of lactic acid bacteria: 它们的多样性和特性]。 their diversity and properties].
已发布 PubMed:基于生物发光的乳链菌肽生产者的鉴定-一种快速简单的食品样品中乳链菌肽菌筛选方法。 Bioluminescence-based identification of nisin producers - a rapid and simple screening method for nisinogenic bacteria in food samples.
已发布 PubMed:Nisa的异源表达与纯化 Heterologous expression and purification of NisA, 来自乳酸乳球菌的羊毛硫抗生素乳链菌肽的前体肽。 the precursor peptide of lantibiotic nisin from Lactococcus lactis.
已发布 PubMed:羊毛硫抗生素与去甲肾上腺素结合的细胞被膜前体的相互作用。 Interaction of type A lantibiotics with undecaprenol-bound cell envelope precursors.
已发布 PubMed:来自热树突土杆菌的羊毛硫抗生素。 Lantibiotics from Geobacillus thermodenitrificans.
已发布 PubMed:生物工程化的乳酸链球菌素衍生物,在复合物基质中具有增强的活性。 Bioengineered nisin derivatives with enhanced activity in complex matrices.
已发布 PubMed:用于控制干酪中单核细胞增生李斯特菌的产细菌素的乳酸乳球菌菌株的技术表征。 Technological characterization of bacteriocin producing Lactococcus lactis strains employed to control Listeria monocytogenes in cottage cheese.
已发布 PubMed:羊乳干酪中产生细菌素的乳酸培养物对拜氏梭菌芽孢的生长抑制作用。 Outgrowth inhibition of Clostridium beijerinckii spores by a bacteriocin-producing lactic culture in ovine milk cheese.
已发布 PubMed:乳链菌肽a的分析 Analysis of nisin A, 乳酸链球菌肽Z及其降解产物,为1cms / ms。
已发布 PubMed:乳酸乳球菌w8的乳链菌肽z制剂在牛奶保存中的潜在应用。 Potential application of the nisin Z preparation of Lactococcus lactis W8 in preservation of milk.
已发布 PubMed:基因编码的抗菌肽 Gene encoded antimicrobial peptides, 设计新型抗分枝杆菌药物的模板。 a template for the design of novel anti-mycobacterial drugs.
已发布 PubMed:乳酸乳球菌亚种的完整基因组序列。乳酸菌cv56 Complete genome sequence of Lactococcus lactis subsp. lactis CV56, 从健康女性的阴道中分离出的益生菌菌株。 a probiotic strain isolated from the vaginas of healthy women.
已发布 PubMed:通过飞行时间二次离子质谱(tof-sims)检测乳链菌肽和纤维蛋白原在聚环氧乙烷涂层聚氨酯表面上的吸附。 Detection of nisin and fibrinogen adsorption on poly(ethylene oxide) coated polyurethane surfaces by time-of-flight secondary ion mass spectrometry (TOF-SIMS).
已发布 PubMed:乳酸链球菌产生乳酸球菌的生物工程,以产生产生天然变体乳酸链球菌素f的等基因菌株 Bioengineering of a Nisin A-producing Lactococcus lactis to create isogenic strains producing the natural variants Nisin F, q和z Q and Z.
已发布 PubMed:乳酸链球菌肽-乳链菌肽的免疫调节功效。 Immunomodulatory efficacy of nisin--a bacterial lantibiotic peptide.
已发布 PubMed:生物工程化的乳链菌肽肽的研究突出了乳链菌肽v的广谱效能。 Studies with bioengineered Nisin peptides highlight the broad-spectrum potency of Nisin V.
已发布 PubMed:edta处理与麦芽糖食杆菌ual307克氏杆菌对革兰氏阴性菌的活性有关。 The activity of bacteriocins from Carnobacterium maltaromaticum UAL307 against gram-negative bacteria in combination with EDTA treatment.
已发布 PubMed:干酪中乳链菌肽基因的表达-一种定量实时聚合酶链反应方法。 Expression of nisin genes in cheese--a quantitative real-time polymerase chain reaction approach.
已发布 PubMed:乳链菌肽改造的前导肽对诱导修饰的要求 Requirements of the engineered leader peptide of nisin for inducing modification, 出口 export, 和分裂。 and cleavage.
已发布 PubMed:I和Iia类细菌素与多粘菌素e联合使用对单核细胞增生性李斯特菌和大肠杆菌耐药变体的抗菌活性。 Antibacterial activity of class I and IIa bacteriocins combined with polymyxin E against resistant variants of Listeria monocytogenes and Escherichia coli.
已发布 PubMed:使用乳清作为替代培养基,优化乳酸乳球菌uq2对乳链菌肽的生产。 Optimization of nisin production by Lactococcus lactis UQ2 using supplemented whey as alternative culture medium.
已发布 PubMed:分离自传统的野生乳酸乳球菌菌株产生的细菌素 Bacteriocins produced by wild Lactococcus lactis strains isolated from traditional, 由原料奶制成的无酵奶酪。 starter-free cheeses made of raw milk.
已发布 PubMed:乳球菌膜通透性抗菌肽。 Lactococcal membrane-permeabilizing antimicrobial peptides.
已发布 PubMed:乳酸链球菌肽的90天口服毒性研究 A 90-day oral toxicity study of nisin A, 一种源自乳酸乳球菌亚种的抗微生物肽。乳酸菌 an anti-microbial peptide derived from Lactococcus lactis subsp. lactis, 在f344大鼠中。 in F344 rats.
已发布 PubMed:进化的乳酸乳球菌菌株可增强重组膜蛋白的表达。 Evolved Lactococcus lactis strains for enhanced expression of recombinant membrane proteins.
已发布 PubMed:菌素asm1的分离与鉴定 Isolation and characterization of plantaricin ASM1: 植物乳杆菌a-1产生的一种新的细菌素。 a new bacteriocin produced by Lactobacillus plantarum A-1.
已发布 PubMed:努卡辛ISK-1 Nukacin ISK-1, 抑菌羊毛硫抗生素。 a bacteriostatic lantibiotic.
已发布 PubMed:Gassericins a和t的作用 Effects of gassericins A and T, 盖氏乳杆菌产生的细菌素 bacteriocins produced by Lactobacillus gasseri, 与甘氨酸蛋c奶油保存。 with glycine on custard cream preservation.
已发布 PubMed:乳链菌肽控制的基因表达系统鉴定生产乳链菌肽的菌株。 Identification of nisin-producing strains by nisin-controlled gene expression system.
已发布 PubMed:第三种天然乳链菌肽变体的生物合成特征和生化特征 Biosynthetic characterization and biochemical features of the third natural nisin variant, 乳链菌肽 nisin A, 由乳酸乳球菌61-14生产。 produced by Lactococcus lactis 61-14.
已发布 PubMed:羊毛硫氨酸氧化使羊毛硫抗生素乳链菌肽失活。 Oxidation of lanthionines renders the lantibiotic nisin inactive.
已发布 PubMed:乳酸菌q Lacticin Q, 乳球菌细菌素 a lactococcal bacteriocin, 在没有特定受体的情况下会导致高水平的膜通透性。 causes high-level membrane permeability in the absence of specific receptors.
已发布 PubMed:从大麦烧酒副产物中获得的发酵大麦提取物用于乳链菌肽的生产。 Utilization of fermented barley extract obtained from a by-product of barley shochu for nisin production.
已发布 PubMed: 乳酸乳球菌亚种中乳链菌肽Z产生的发生率。从泰国发酵食品中分离出的乳酸菌tff 221。
已发布 PubMed:乳链菌肽q的完整共价结构 Complete covalent structure of nisin Q, 新的天然乳链菌肽变体 new natural nisin variant, 包含翻译后修饰的氨基酸。 containing post-translationally modified amino acids.
已发布 PubMed: 抗菌肽曲霉素 divergicin m35和nisin a对单核细胞增生李斯特菌lsd530钾通道的影响
已发布 PubMed:酪蛋白jm79的克隆和异源生产 Cloning and heterologous production of Hiracin JM79, 平肠肠球菌dch5产生的sec依赖性细菌素 a Sec-dependent bacteriocin produced by Enterococcus hirae DCH5, 在乳酸菌和毕赤酵母中。 in lactic acid bacteria and Pichia pastoris.
已发布 PubMed:突变蛋白1140的抗菌机理的阐明。 Elucidation of the antimicrobial mechanism of mutacin 1140.
已发布 PubMed: 成熟的片球菌素 pediocin pa-1嵌合体与肠球菌素p的信号肽融合,可以进行克隆 , 生产 production, 乳酸菌中片球菌素 pediocin pa-1的表达和表达。
已发布 PubMed:乳链菌肽a的体外抑制活性 In vitro inhibition activity of nisin A, 乳链菌肽Z , 片球菌素 pediocin pa-1和针对常见肠道细菌的抗生素。
已发布 PubMed:通过环a和b的诱变以及c端截短来分离和调节乳链菌肽的四个不同活性。 Dissection and modulation of the four distinct activities of nisin by mutagenesis of rings A and B and by C-terminal truncation.
已发布 PubMed: 单核细胞增生李斯特菌中的I类/ ia IIa类细菌素交叉耐药现象。
已发布 PubMed: epsilon-poly-l-赖氨酸和nisin协同作用对革兰氏阳性食源性致病菌蜡样芽孢杆菌和单核细胞增生李斯特菌。
已发布 PubMed:克隆 Cloning, 肠球菌球菌plbc21在乳酸乳球菌中产生的细菌素肠球菌素a的表达和表达。 production and expression of the bacteriocin enterocin A produced by Enterococcus faecium PLBC21 in Lactococcus lactis.
已发布 PubMed:乳酸q的结构分析与表征 Structural analysis and characterization of lacticin Q, 一种新的细菌素,属于革兰氏阳性细菌未修饰的细菌素新家族。 a novel bacteriocin belonging to a new family of unmodified bacteriocins of gram-positive bacteria.
已发布 PubMed:奥克斯加尔对双歧杆菌抗生素敏感性的影响 Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, 和过氧化氢的压力。 and hydrogen peroxide stress.
已发布 PubMed:靶向脂质的羊毛硫抗生素肽的另一种杀菌作用机理ii。 An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.
已发布 PubMed:真核和原核抗菌肽体外对肠上皮细胞的细胞毒性研究 Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro.
已发布 PubMed:乳房链球菌产生的新型乳链菌肽变异体的分子和遗传特征。 Molecular and genetic characterization of a novel nisin variant produced by Streptococcus uberis.
已发布 PubMed:乳酸乳球菌粪便肠球菌p13中sec依赖肠球蛋白p的高水平异源生产和功能表达。 High-level heterologous production and functional expression of the sec-dependent enterocin P from Enterococcus faecium P13 in Lactococcus lactis.
已发布 PubMed:一种新型的免疫蛋白 A novel type of immunity protein, 努赫 NukH, 用于华纳熊果isk-1产生的羊毛硫抗生素核蛋白 nukacin isk-1。
已发布 PubMed:高压处理和产生细菌素的乳酸菌联合作用对大肠杆菌o157的灭活作用 Combined effect of high-pressure treatments and bacteriocin-producing lactic acid bacteria on inactivation of Escherichia coli O157:h7在生奶奶酪中。 H7 in raw-milk cheese.
已发布 PubMed:产细菌素的乳酸菌接种牛奶对瑞士乳杆菌辅助干酪培养的影响。 Effect of milk inoculation with bacteriocin-producing lactic acid bacteria on a Lactobacillus helveticus adjunct cheese culture.
已发布 PubMed:乳链菌肽-脂质ii孔的组装和稳定性。 Assembly and stability of nisin-lipid II pores.
已发布 PubMed:乳酸乳球菌高水平联合生产细菌素乳链菌肽a和乳球菌a。 High-level coproduction of the bacteriocins nisin A and lactococcin A by Lactococcus lactis.
已发布 PubMed:肽抗生素乳链菌肽对脂质ii介导的孔形成 Lipid II-mediated pore formation by the peptide antibiotic nisin: 黑脂质膜研究。 a black lipid membrane study.
已发布 PubMed:用于固定生物活性剂的改性藻酸盐基质。 Modified alginate matrices for the immobilization of bioactive agents.
已发布 PubMed:乳酸3147的结构表征 Structural characterization of lacticin 3147, 具有协同活性的两肽羊毛硫抗生素。 a two-peptide lantibiotic with synergistic activity.
已发布 PubMed:羊毛硫抗生素乳链菌肽q的鉴定 Identification of the lantibiotic nisin Q, 由日本河中分离出的乳酸乳球菌61-14产生的一种新的天然乳链菌肽变体。 a new natural nisin variant produced by Lactococcus lactis 61-14 isolated from a river in Japan.
已发布 PubMed:通过使用裂解性噬菌体和细菌素处理对鲜切产品上的单核细胞增生李斯特菌进行生物防治。 Biocontrol of Listeria monocytogenes on fresh-cut produce by treatment with lytic bacteriophages and a bacteriocin.
已发布 PubMed:乳酸链球菌菌素生产乳酸球菌亚种的鉴定和特征。从泡菜中分离出的乳酸菌。 Identification and characteristics of nisin Z-producing Lactococcus lactis subsp. lactis isolated from Kimchi.
已发布 PubMed:抗菌肽乳链菌肽a的聚乙二醇化 PEGylation of the antimicrobial peptide nisin A: 问题和观点。 problems and perspectives.
已发布 PubMed:乳酸乳球菌是功能性膜蛋白过量生产的宿主。 Lactococcus lactis as host for overproduction of functional membrane proteins.
已发布 PubMed:乳酸菌细菌素对幽门螺杆菌的拮抗作用。 Antagonism of Helicobacter pylori by bacteriocins of lactic acid bacteria.
已发布 PubMed:单核细胞增多性李斯特菌中细菌素耐药性发展的频率以及相关的适应性成本。 Frequency of bacteriocin resistance development and associated fitness costs in Listeria monocytogenes.
已发布 PubMed:乳链菌肽z单克隆抗体的生产与表征 Production and characterization of anti-nisin Z monoclonal antibodies: 通过竞争性酶免疫测定法区分活性形式和非活性形式的适用性。 suitability for distinguishing active from inactive forms through a competitive enzyme immunoassay.
已发布 PubMed:对产生诱变素或羊毛硫抗生素的细菌菌株的病原体的活性谱的比较。 Comparison of the activity spectra against pathogens of bacterial strains producing a mutacin or a lantibiotic.
已发布 PubMed:用产生细菌素的乳酸菌培养乳酸发酵剂的效果。 The effects of cultivating lactic starter cultures with bacteriocin-producing lactic acid bacteria.
已发布 PubMed: 李斯特菌菌株对ia IIa类细菌素敏感性的自然变化。
已发布 PubMed: 分离自wara wara的乳酸乳球菌bfe 1500中乳链菌肽z的产生 , 传统的尼日利亚奶酪产品。 a traditional Nigerian cheese product.
已发布 PubMed:突变蛋白b-ny266的麦克风 MICs of mutacin B-Ny266, 乳链菌肽 nisin A, 万古霉素 vancomycin, 和奥沙西林可抵抗细菌性病原体。 and oxacillin against bacterial pathogens.
已发布 PubMed:羊毛硫抗生素乳链菌肽 The lantibiotic nisin, 有没有特殊情况? a special case or not?
已发布 PubMed: 乳酸乳球菌增强了片球菌素 pediocin pa-1的生产以及乳链菌肽和片球菌素 pediocin pa-1的联合生产。
已发布 PubMed:乳链菌肽的翻译后修饰。 nisb参与脱水过程。 Post-translational modification of nisin. The involvement of NisB in the dehydration process.
已发布 PubMed: 乳酸链球菌肽消耗细胞内的atp ATP,并以杀菌的方式对抗耻垢分枝杆菌。
已发布 PubMed:菌落杂交技术检测特定的产生细菌素的乳酸菌。 Detection of specific bacteriocin-producing lactic acid bacteria by colony hybridization.
已发布 PubMed:傅里叶变换离子回旋共振质谱法对乳链菌肽a及其某些变体进行分析 Analysis of nisin A and some of its variants using Fourier transform ion cyclotron resonance mass spectrometry.
已发布 PubMed:羊毛硫抗生素乳链菌肽的生物合成中最终中间体的结构特征。前导肽的影响。 Structural features of the final intermediate in the biosynthesis of the lantibiotic nisin. Influence of the leader peptide.
已发布 PubMed:通过免疫亲和层析一步纯化乳链菌肽a。 One-step purification of nisin A by immunoaffinity chromatography.
已发布 PubMed:用模型膜系统研究变体和片段乳链菌肽的结构-功能关系。 Structure-function relations of variant and fragment nisins studied with model membrane systems.
已发布 PubMed:化学修饰的乳链菌肽种的结构和生物学活性。 Structure and biological activity of chemically modified nisin A species.
已发布 PubMed:在高乳链菌肽浓度下生长的无乳李斯特菌抗乳链菌肽变体中细胞壁的变化。 Cell wall changes in nisin-resistant variants of Listeria innocua grown in the presence of high nisin concentrations.
已发布 PubMed:乳链菌肽的多克隆抗体的产生 Generation of polyclonal antibodies against nisin: 免疫策略和免疫分析开发。 immunization strategies and immunoassay development.
已发布 PubMed:乳链菌肽降解产物的研究 Studies of the degradation products of nisin, 肽类抗生素 a peptide antibiotic, 使用毛细管电泳和离线质谱分析。 using capillary electrophoresis with off-line mass spectrometry.
已发布 PubMed:乳链菌肽生物合成的遗传决定因素 Genetic determinants for the biosynthesis of nisin, 乳酸乳球菌产生的细菌素。 a bacteriocin produced by Lactococcus lactis.
已发布 PubMed:羊毛硫蛋白的蛋白质工程。 Protein engineering of lantibiotics.
已发布 PubMed:枯草蛋白酶和乳链菌肽生物合成的遗传学 Genetics of subtilin and nisin biosyntheses: 羊毛硫抗生素的生物合成。 biosynthesis of lantibiotics.
已发布 PubMed:[乳链菌肽 [Nisin, 一种潜在的局部制剂防腐剂]。 a potential preservative for topical preparations].
已发布 PubMed: 乳链菌肽Z , 突变的乳酸链球菌素z和乳酸霉素481与阴离子脂质的相互作用与抗菌活性相关。单层研究。 mutant nisin Z and lacticin 481 interactions with anionic lipids correlate with antimicrobial activity. A monolayer study.
已发布 PubMed:溶解度和稳定性的改善通过蛋白质工程制备抗菌肽乳链菌肽。 Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering.
已发布 PubMed:阐明了表皮熊果k7中羊毛硫抗生素表兰霉素k7的一级结构。 Epilancin-k7编码基因的克隆,鉴定和成熟Epilancin k7的nmr分析。 Elucidation of the primary structure of the lantibiotic epilancin K7 from Staphylococcus epidermidis K7. Cloning and characterisation of the epilancin-K7-encoding gene and NMR analysis of mature epilancin K7.
已发布 PubMed:从干发酵香肠中分离产生乳链菌肽的乳酸乳球菌菌株。 Isolation of nisin-producing Lactococcus lactis strains from dry fermented sausages.
已发布 PubMed:利用乳糖的乳球菌的检测和鉴定。在自然生态系统中。 Detection and characterization of lactose-utilizing Lactococcus spp. in natural ecosystems.
已发布 PubMed:乳酸乳球菌n8中尼日菌操纵子的密码子用法表明,乳酸菌球菌-蔗糖转座子的非乳球菌起源。 The codon usage of the nisZ operon in Lactococcus lactis N8 suggests a non-lactococcal origin of the conjugative nisin-sucrose transposon.
已发布 PubMed:乳酸乳球菌中乳酸链球菌素-蔗糖元素的分布和演变 Distribution and evolution of nisin-sucrose elements in Lactococcus lactis.
已发布 PubMed: 乳酸乳球菌的乳酸链球菌肽Z前体的生物合成和分泌 , 由枯草芽孢杆菌的同源羊毛硫抗生素枯草蛋白酶的前导肽指导。 directed by the leader peptide of the homologous lantibiotic subtilin from Bacillus subtilis.
已发布 PubMed:乳酸乳球菌乳链菌肽基因簇nisabtcipr的表征。 nisa和nisi基因表达对免疫力发展的要求。 Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity.
已发布 PubMed:基于乳链菌肽的漱口水的作用 The effect of a mouthrinse based on nisin, 细菌素 a bacteriocin, 对小猎犬的牙菌斑和牙龈炎的影响。 on developing plaque and gingivitis in beagle dogs.
已发布 PubMed:乳酸乳球菌乳链菌肽操纵子基因nisp的鉴定 Characterization of the Lactococcus lactis nisin A operon genes nisP, 编码参与前体加工的枯草杆菌蛋白酶样丝氨酸蛋白酶 encoding a subtilisin-like serine protease involved in precursor processing, 和nisr and nisR, 编码参与乳链菌肽生物合成的调节蛋白。 encoding a regulatory protein involved in nisin biosynthesis.
已发布 PubMed:来自鱼腥藻的15n和13c标记的培养基。用于细菌素的通用同位素标记 15N- and 13C-labeled media from Anabaena sp. for universal isotopic labeling of bacteriocins: 明胶隐球菌白蛋白a和乳酸乳球菌的乳链菌肽a的nmr共振分配。 NMR resonance assignments of leucocin A from Leuconostoc gelidum and nisin A from Lactococcus lactis.
已发布 PubMed: 乳链菌肽Z的特性及其基因分布 , 尼兹 nisZ, 在乳酸乳球菌中。 in Lactococcus lactis.
已发布 PubMed:工程化抗菌肽乳链菌肽中的脱水氨基酸残基。 Engineering dehydrated amino acid residues in the antimicrobial peptide nisin.
已发布 PubMed:乳链菌肽a及其两个主要降解产物的溶液结构,由n.m.r. Solution structures of nisin A and its two major degradation products determined by n.m.r.
已发布 PubMed:[乳链菌肽研究 [Study of nisin, 乳酸链球菌培养物产生的多肽抗生素 a polypeptide antibiotic produced by a culture of Streptococcus lactis, 应变msu]。 strain MSU].
已发布 PubMed:乳链菌肽的一些化学和物理性质 Some chemical and physical properties of nisin, 乳酸乳球菌产生的一种小蛋白抗生素。 a small-protein antibiotic produced by Lactococcus lactis.
已发布 PubMed:Nisin, 肽类抗生素 a peptide antibiotic: Nisa基因的克隆和测序以及其肽产物的翻译后加工。 cloning and sequencing of the nisA gene and posttranslational processing of its peptide product.
已发布 PubMed:Structure, 表达 expression, 乳链菌肽前体的基因的合成和进化 and evolution of a gene encoding the precursor of nisin, 一种小蛋白抗生素。 a small protein antibiotic.
已发布 PubMed:某些抗生素对bolt鱼(罗非鱼)饲养质量的影响。 The effect of certain antibiotics on the keeping quality of bolti fish (Tilapia nilotica).
已发布 PubMed:Nisin: 在肉类保存中可能替代亚硝酸盐或与之相辅相成。 a possible alternative or adjunct to nitrite in the preservation of meats.
已发布 PubMed:乳链菌肽的分子量和化学组成的观察 Observations on the molecular weight and chemical composition of nisin A.
 
笔记 Notes:
一种由乳酸链球菌产生的34个氨基酸多肽抗生素。它已被用作水果罐头和蔬菜中的食品防腐剂 a 34-amino acid polypeptide antibiotic produced by streptococcus lactis. it has been used as a food preservative in canned fruits and vegetables, 和奶酪。食品防腐剂 and cheese. Food preservative, 尤其是奶酪对革兰氏阳性细菌特别是梭状芽孢杆菌和芽孢杆菌具有活性(抗菌作用适用于孢子和营养细胞) esp. for cheese. Active against Gram-positive bacteria - particularly Clostridium and Bacillus (the antibacterial action applies to both spores and vegetative cells), 而且还有单核细胞增生李斯特菌和乳酸菌。乳链菌肽不影响革兰氏阴性菌 but also Listeria monocytogenes and lactic acid bacteria. Nisin does not affect Gram-negative bacteria, 酵母和霉菌。它已经在商业上用作食品防腐剂已有50多年的历史了,没有任何细菌抗药性的证据[dfc] yeasts and moulds. It has been used for over 50 years commercially as a food preservative without any evidence of bacterial resistance [DFC]
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