genistin
4',5,7-三羟基异黄酮7-d-葡萄糖苷 7-trihydroxyisoflavone 7-D-glucoside

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Name: 5-羟基-3-（4-羟基苯基）-7-[（2s 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-三羟基-6-（羟甲基）恶烷-2-基]氧化铬-4- 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one CAS号 CAS Number: 529-59-9 3D/INCHI FDA UNII: 1POG3SCN5T nikkaji网站 Nikkaji Web: J40.719D 贝尔斯坦数 Beilstein Number: 0064479 MDL : mfcd00016883 MFCD00016883 XlogP3-AA: 0.90（est） 0.90 (est) 分子量 Molecular Weight: 432.38240000 式 Formula: c21 h20 o10 C21 H20 O10 生物活性总结 BioActivity Summary: 清单 listing 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:antioxidants   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search 已发布 PubMed: 搜索 Search NCBI: 搜索 Search   物理性质 Physical Properties: 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 沸点 Boiling Point: 788.90 °C. @ 760.00 mm 汞 Hg (est) 闪点 Flash Point: 537.00 °F. tcc TCC ( 280.70 °C. ) (est) logp（o / w） logP (o/w): 0.790（est） 0.790 (est) 溶于 Soluble in:   水 water, 1417 mg / l @ 25°c（est） 1417 mg/L @ 25 °C (est)   感官特性 Organoleptic Properties: 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: CosIng: 化妆品数据 cosmetic data 化妆品用途 Cosmetic Uses: antioxidants 皮肤调理 skin conditioning   供应商 Suppliers: BOC Sciences 仅供实验/研究使用。 For experimental / research use only. Genistin 库姆波 Coompo 仅供实验/研究使用。 For experimental / research use only. Genistin from 植物 Plants ≥98.5% 气味 Odor: characteristic 采用 Use: 在大豆类食品中发现的异黄酮苷。这是ptk抑制剂金雀异黄素的无活性类似物，可用作金雀异黄素的阴性对照。 An isoflavone glycoside found in soy-based food products. This is an inactive analog of the PTK inhibitor Genistein and can be used as a negative control for Genistein. Genistin, 像染料木黄酮 like genistein, 是一种植物雌激素，因为它在体内可刺激雌激素依赖性乳腺癌细胞的生长。 is a phytoestrogen as it was shown to stimulate estrogen- dependent breast cancer cell growth in vivo. 染料木黄酮和其他异黄酮在新生儿肠道内具有生物活性，可以降低轮状 感染的严重性；单独的genistin表现出40-60％的 感染性抑制。 Genistin and other isoflavones are demonstrated to be bioactive within the neonatal intestine and may reduce the severity of rotavirus infections; genistin alone shows inhibition of the viral infectivity by 40-60%. 体外研究表明，染料木黄酮和染料木黄酮都能够增强老年大鼠股骨干phy端组织的骨代谢。报道减少 切除大鼠的骨质流失。 In vitro study have shown that both genistin and genistein are capable of enhancing bone metabolism in the femoral-metaphyseal tissues of elderly rats. Reported to reduce bone loss in ovarectomized rats. Emd 微孔 Millipore 仅供实验/研究使用。 For experimental / research use only. Genistin sds 外合成 ExtraSynthese 仅供实验/研究使用。 For experimental / research use only. 染料木素（hplc）≥99％ Genistin (HPLC) ≥99% 美国纳卡拉 Nacalai USA 仅供实验/研究使用。 For experimental / research use only. Genistin 圣克鲁斯生物技术 Santa Cruz Biotechnology 仅供实验/研究使用。 For experimental / research use only. 染料木素≥99％ Genistin ≥99% sds 西格玛·奥尔德里奇 Sigma-Aldrich 仅供实验/研究使用。 For experimental / research use only. Genistin 分析analytical standard   安全信息 Safety Information: 首选SDS Preferred SDS: 视图 View   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 腹腔内小鼠 intraperitoneal-老鼠 mouse LD50 > 2000 mg/kg Pharmaceutical 化学 Chemistry 日志 Journal 卷 Vol. 13, pg。 51 Pg. 51, 1979. 皮肤毒性 Dermal Toxicity: 未定 Not determined 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: antioxidants 染料木苷使用水平的推荐 Recommendation for genistin usage levels up to:   不用于香水。 not for fragrance use.   genistin风味使用水平的推荐值 Recommendation for genistin flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: 欧洲食品安全局（efsa EFSA）参考 : 预备 Preparatory 工作 work to support the 风险 risk 评定 assessment for 周围 peri- and 绝经后 post更年期 menopausal 女 women 服用 taking food 补品 supplements 包含 containing 隔离的 isolated 异黄酮 异黄酮 isoflavones 视图 View page or 视图 View pdf 风险 Risk 评定 assessment for 周围 peri- and 绝经后 post-更年期 menopausal 女 women 服用 taking food 补品 supplements 包含 containing 隔离的 isolated 异黄酮 异黄酮 isoflavones 视图 View page or 视图 View pdf Epi系统 EPI System: 视图 View 癌症引文 Cancer Citations:搜索 Search 毒理学引文 Toxicology Citations:搜索 Search 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（SRS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :5281377 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data 德国wgk WGK Germany:3 5-羟基-3-（4-羟基苯基）-7-[（2s 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-三羟基-6-（羟甲基）恶烷-2-基]氧化铬-4- 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one chemidplus Chemidplus:0000529599 技术 RTECS:CAS＃529-59-9的dj3093000 DJ3093000 for cas# 529-59-9   参考资料 References:   5-羟基-3-（4-羟基苯基）-7-[（2s 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-三羟基-6-（羟甲基）恶烷-2-基]氧化铬-4- 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI pubchem（cid） Pubchem (cid): 5281377 pubchem（sid） Pubchem (sid): 135050235   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View KEGG (GenomeNet): C09126 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): HMDB33988 食物 FooDB: FDB012221 vcf在线 VCF-Online: 食品中的挥发性有机化合物 VCF Volatile Compounds in Food 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and core 组件 components note 没找到 None Found   潜在用途 Potential Uses: 没找到 None Found   存在（自然 Occurrence (nature, food, 其他） other):note   樱桃酸樱桃果 cherry sour cherry fruit 搜索 Search Trop Picture   樱桃甜樱桃 cherry sweet cherry 搜索 Search Trop Picture   羽扇豆白lupine white lupine 搜索 Search Trop Picture   大豆子叶 soybean cotyledon 搜索 Search Trop Picture   大豆下胚轴 soybean hypocotyl 搜索 Search Trop Picture   大豆种子 soybean seed 搜索 Search Trop Picture   大豆种皮 soybean seed coat 搜索 Search Trop Picture   大豆芽 soybean shoot 搜索 Search Trop Picture   大豆睾丸 soybean testa 搜索 Search Trop Picture   同义词 Synonyms: 4H-1- benzopyran-4-one, 7- (＆beta beta &beta beta;-d-吡喃葡萄糖基氧基 -D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl nyl)- 4H-1- benzopyran-4-one, 7-(＆beta beta &beta beta;-d-吡喃葡萄糖基氧基 -D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl nyl)- 异 iso flavone, 4',5,7-三羟基 7-trihydroxy-, 7-D-glucoside   金雀异黄素 genistein 7-glucoside   金雀异黄素 genistein 7-O-b-D-glucoside   金雀异黄素 genistein glucoside   染料木醇 genisteol 7-monoglucoside   genistin (8CI)   genistoside 7-(b-D- glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl nyl)-4h-1-苯并吡喃-4-酮 4H-1-benzopyran-4-one 5- hydroxy-3-(4-hydroxyphenyl nyl)-7-[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-三羟基-6-（羟甲基）恶烷-2-基]氧化铬-4- 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 5- hydroxy-3-(4-hydroxyphenyl nyl)-7-{[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-trihydroxy-6-(hydroxyme硫醇 thyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-铬 chromen-4-one 5- hydroxy-3-(4-hydroxyphényl nyl)-7-{[(2S,3r 3R,4s 4S,5s 5S,6r）-3 6R)-3,4,5-trihydroxy-6-(羟胺 hydroxymé硫醇 thyl)＆ tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one 4',5,7- trihydroxy异黄酮 isoflavone 7-D-glucoside   文章 Articles: 已发布 PubMed:大豆成分中的异黄酮以及子叶和胚轴中芽时间的影响。 Isoflavones of the Soybean Components and the Effect of Germination Time in the Cotyledons and Embryonic Axis. 已发布 PubMed:酸樱桃（李子）品种中的染料木黄酮异黄酮糖缀合物。 Genistein isoflavone glycoconjugates in sour cherry (Prunus cerasus L.) cultivars. 已发布 PubMed:大豆异黄酮含量形式的分布图以及芽时间对这些化合物的影响以及大豆芽的物理参数。 Profile of the contents of different forms of soybean isoflavones and the effect of germination time on these compounds and the physical parameters in soybean sprouts. 已发布 PubMed:异黄酮调节糖基化。 Glycation is regulated by isoflavones. 已发布 PubMed:豆浆发酵过程中β-葡萄糖苷酶活性和异黄酮的生物转化。 β-Glucosidase activity and bioconversion of isoflavones during fermentation of soymilk. 已发布 PubMed:黃芩提取物通过诱导g2 / m细胞周期停滞并通过bax和caspase途径激活erk依赖的细胞凋亡对肝星状细胞的抑制作用。 Identification and quantification of the main isoflavones and other phytochemicals in soy based nutraceutical products by liquid chromatography-orbitrap high resolution mass spectrometry. 已发布 PubMed:与未缀合的β-葡萄糖苷形式的大鼠相比，异黄酮的丙二酰葡萄糖苷缀合物的生物利用度低得多。 Malonylglucoside conjugates of isoflavones are much less bioavailable compared with unconjugated β-glucosidic forms in rats. 已发布 PubMed:大豆[大豆（美金）种质]异黄酮谱及其与代谢途径的相关性。 Isoflavones profiling of soybean [Glycine max (L.) Merrill] germplasms and their correlations with metabolic pathways. 已发布 PubMed:异黄酮的摄入抑制7的发展 Isoflavone intake inhibits the development of 7,在正常和去 大鼠中，由12-二甲基苯并（a）蒽（dmba）诱导的乳腺肿瘤。 12-dimethylbenz(a)anthracene(DMBA)-induced mammary tumors in normal and ovariectomized rats. 已发布 PubMed:与非转基因大豆基因型的营养和工业品质有关的化合物。 Chemical compounds related to nutraceutical and industrial qualities of non-transgenic soybean genotypes. 已发布 PubMed:主要大豆异黄酮的抑制作用 Inhibitory effects of a major soy isoflavone, 金雀异黄素 genistein, 对 脱氧核糖核酸 DNA拓扑异构酶ii活性和癌细胞增殖的影响。 已发布 PubMed:黃芩素功能化的磁性纳米粒子用于磁性固相快速萃取法选择性测定豆浆中的异黄酮。 Rapid magnetic solid-phase extraction for the selective determination of isoflavones in soymilk using baicalin-functionalized magnetic nanoparticles. 已发布 PubMed:通过使用废咖啡渣作为β-葡萄糖苷酶的固定剂，可在黑豆浆中富集两种异黄酮苷元。 Enrichment of two isoflavone aglycones in black soymilk by using spent coffee grounds as an immobiliser for β-glucosidase. 已发布 PubMed: 峨参（峨参 Colletotrichum 球 gloeosporioides）感染的大豆（甘氨酸最高含量）豆芽中酚类化合物含量变化的测定。 已发布 PubMed:大豆异黄酮苷元和糖苷形式的光保护作用的比较分析。 A comparative analysis of the photo-protective effects of soy isoflavones in their aglycone and glucoside forms. 已发布 PubMed:通过固定在固体载体上的β-葡萄糖苷酶富集黑豆浆中的两种异黄酮苷元。 Enrichment of two isoflavone aglycones in black soymilk by immobilized β-glucosidase on solid carriers. 已发布 PubMed:一种改进的猝灭剂方法作为样品处理，然后通过超高效液相色谱-三重四极杆质谱法测定食品中的异黄酮。 A modified QuEChERS method as sample treatment before the determination of isoflavones in foods by ultra-performance liquid chromatography-triple quadrupole mass spectrometry. 已发布 PubMed:欧盟市场上的婴儿配方中的染料木黄酮和双羧酰亚胺杀菌剂。 Genistein and dicarboximide fungicides in infant formulae from the EU market. 已发布 PubMed:大叶黄花和甘氨酸绒毛根的抗氧化和抗酪氨酸酶活性。 Antioxidant and Antityrosinase Activity of Flemingia macrophylla and Glycine tomentella Roots. 已发布 PubMed:通过uhplc-uv快速同时测定豆浆中的游离和缀合的异黄酮。 Fast simultaneous determination of free and conjugated isoflavones in soy milk by UHPLC-UV. 已发布 PubMed:煮熟和体外消化的大豆对 前列腺癌细胞的凋亡作用。 Apoptotic effects of cooked and in vitro digested soy on human prostate cancer cells. 已发布 PubMed:异黄酮和香豆酚在被忽视的热带和亚热带豆科植物中的分布。 Distribution of isoflavones and coumestrol in neglected tropical and subtropical legumes. 已发布 PubMed:用大鼠全胚培养和肢体微团培养方法比较金雀异黄素和染料木素的致畸性。 Comparative evaluation of the teratogenicity of genistein and genistin using rat whole embryo culture and limbud micromass culture methods. 已发布 PubMed:体外和动物模型对豆浆发酵液的杀菌活性 Bactericidal activity of soymilk fermentation broth by in vitro and animal models. 已发布 PubMed:类黄酮 Flavonoids, 饮食中普遍存在的酚类 a ubiquitous dietary phenolic subclass, 发挥广泛的体外抗侵袭和体内抗转移活性。 exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. 已发布 PubMed:染料木素的吸收和血浆分布与健康女性中的染料木素不同。 Absorption and plasma disposition of genistin differ from those of genistein in healthy women. 已发布 PubMed:激烈热球菌的热稳定β-葡萄糖苷酶水解异黄酮苷。 Hydrolysis of isoflavone glycosides by a thermostable β-glucosidase from Pyrococcus furiosus. 已发布 PubMed:乳芽孢杆菌对口服异黄酮生物利用度的影响 Effect of Lactobacillus sporogenes on oral isoflavones bioavailability: 更年期妇女的单剂量药代动力学研究。 single dose pharmacokinetic study in menopausal women. 已发布 PubMed:杏仁粉对发酵大豆食品中异黄酮的影响。 Modification of isoflavone profiles in a fermented soy food with almond powder. 已发布 PubMed:ntp-cerhr专家小组报告了大豆婴儿配方食品的发育毒性。 NTP-CERHR expert panel report on the developmental toxicity of soy infant formula. 已发布 PubMed:大豆异黄酮和其他异黄酮可激活 类苦味受体htas2r14和htas2r39。 Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39. 已发布 PubMed:破囊壶菌gh3家族β-葡萄糖苷酶的表征及其在废咖啡渣中异黄酮糖苷水解中的应用。 Characterization of a GH3 family β-glucosidase from Dictyoglomus turgidum and its application to the hydrolysis of isoflavone glycosides in spent coffee grounds. 已发布 PubMed: 中华dra（cudrania Cudrania chINCHInensis cochINCHInensis）茎中的酚类酪氨酸酶抑制剂。 已发布 PubMed:超声处理后，添加生物素的豆浆中乳酸菌的生长增加，异黄酮生物转化。 Enhanced growth of lactobacilli and bioconversion of isoflavones in biotin-supplemented soymilk upon ultrasound-treatment. 已发布 PubMed:基于生物测定的动物饲料和补品中类固醇衍生物的筛选。 Bioassay based screening of steroid derivatives in animal feed and supplements. 已发布 PubMed:于大豆异黄酮糖苷水解中三种热稳定β-葡萄糖苷酶的Comparison of three thermostable β-glucosidases for application in the hydrolysis of soybean isoflavone glycosides. 已发布 PubMed:优化大豆胚芽粉中异黄酮葡萄糖苷酶促转化为糖苷配基的时间和温度。 Optimizing time and temperature of enzymatic conversion of isoflavone glucosides to aglycones in soy germ flour. 已发布 PubMed:豆科植物异黄酮对酵母α-葡萄糖苷酶的抑制作用，可作为阿卡波糖的体外替代品。 Yeast α-glucosidase inhibition by isoflavones from plants of Leguminosae as an in vitro alternative to acarbose. 已发布 PubMed:凝结剂对异黄酮和豆腐抗氧化活性的影响 Influence of natural coagulants on isoflavones and antioxidant activity of tofu. 已发布 PubMed:类黄酮对葛根中草药质量的评价 Evaluation of quality of Radix Puerariae herbal medicine by isoflavonoids. 已发布 PubMed:芽孢杆菌属物种形成琥珀酰genistin和琥珀酰大豆苷。 Formation of succinyl genistin and succinyl daidzin by Bacillus species. 已发布 PubMed:大豆提取物和大豆异黄酮对前列腺癌细胞凋亡的不同影响。 Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. 已发布 PubMed:纳豆芽孢杆菌发酵过程中发酵的黑大豆纳豆的特性分析。 Characterization of fermented black soybean natto inoculated with Bacillus natto during fermentation. 已发布 PubMed:异黄酮的综合概况 Comprehensive profiling of isoflavones, 植物甾醇 phytosterols, tocopherols, 矿物质 minerals, 粗蛋白质 crude protein, lipid, 和大豆芽过程中的糖（最大甘氨酸）。 and sugar during soybean (Glycine max) germination. 已发布 PubMed:姬松茸深层培养液中的半纯化部分可降低链脲佐菌素诱导的糖尿病大鼠的血糖水平。 Semipurified fractions from the submerged-culture broth of Agaricus blazei Murill reduce blood glucose levels in streptozotocin-induced diabetic rats. 已发布 PubMed:大豆提取物的1h nmr指纹图谱 1H NMR fingerprinting of soybean extracts, 着重于异黄酮的鉴定和定量。 with emphasis on identification and quantification of isoflavones. 已发布 PubMed:Genistin和低聚果糖的组合可防止 激素缺乏时的骨质流失。 Combination of genistin and fructooligosaccharides prevents bone loss in ovarian hormone deficiency. 已发布 PubMed:葛根及其水解产物对nhek细胞中透明质酸产生的刺激作用的Comparison of Puerariae Radix and its hydrolysate on stimulation of hyaluronic acid production in NHEK cells. 已发布 PubMed:补充益生元的豆浆中益生菌对血管紧张素i转化酶的抑制活性和异黄酮的生物转化。 Angiotensin I-converting enzyme inhibitory activity and bioconversion of isoflavones by probiotics in soymilk supplemented with prebiotics. 已发布 PubMed:大豆配方和异黄酮与正在发育的肠道。 Soy formula and isoflavones and the developing intestine. 已发布 PubMed:使用hplc技术进行大豆衍生品中异黄酮含量的色谱定量。 Chromatographic quantification of isoflavone content from soy derivates using HPLC technique. 已发布 PubMed:膳食类黄酮的糖基化会降低血浆蛋白的亲和力。 Glycosylation of dietary flavonoids decreases the affinities for plasma protein. 已发布 PubMed:红曲霉发酵大豆提取物对高脂高胆固醇饮食大鼠的降血脂作用。 Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet. 已发布 PubMed:异黄酮糖苷化对老年雄性大鼠生物利用度和药代动力学的影响 Effect of glycosidation of isoflavones on their bioavailability and pharmacokinetics in aged male rats. 已发布 PubMed:比较用于治疗更年期不适的含异黄酮补充剂的激素活性。 Comparison of hormonal activity of isoflavone-containing supplements used to treat menopausal complaints. 已发布 PubMed:纳米黑大豆增强衰老加速小鼠的免疫反应。 Nanonized black soybean enhances immune response in senescence-accelerated mice. 已发布 PubMed:不同条件下蒸黑豆和黑豆曲中异黄酮异构体的稳定性 Stability of isoflavone isomers in steamed black soybeans and black soybean koji stored under different conditions. 已发布 PubMed:增强了用不同的产生β-葡糖苷酶的真菌发酵的大豆粉的体外和体内抗氧化活性和游离酚类化合物的动员。 Enhanced in vitro and in vivo antioxidant activity and mobilization of free phenolic compounds of soybean flour fermented with different beta-glucosidase-producing fungi. 已发布 PubMed:比较代谢谱显示与大豆耐盐性相关的次生代谢产物。 Comparative metabolic profiling reveals secondary metabolites correlated with soybean salt tolerance. 已发布 PubMed:植物雌激素和乳腺癌 Phytoestrogens and breast cancer: 一个复合物的故事。 a complex story. 已发布 PubMed:黄素光敏化对豆浆中异黄酮变化的影响 Effects of riboflavin photosensitization on the changes of isoflavones in soymilk. 已发布 PubMed:明尼苏达州北部地区种植的食用大豆中酚类物质的特征和抗氧化特性 Characterization of phenolic substances and antioxidant properties of food soybeans grown in the North Dakota-Minnesota region. 已发布 PubMed:ma树黑莓黑麦茧/愈合组织培养物中的异黄酮成分。等等 Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim. 已发布 PubMed:益生菌酵母和细菌发酵的豆浆的生物分子和营养品质。 Biomolecules and nutritional quality of soymilk fermented with probiotic yeast and bacteria. 已发布 PubMed: Genistin和依普黄酮 ipriflavone的组合可防止乳腺肿瘤发生并调节脂质分布。 已发布 PubMed:脱脂奶粉补充会影响乳糖利用率 Skim milk powder supplementation affects lactose utilization, 乳酸菌在豆浆中的微生物存活率和异黄酮苷的生物转化为异黄酮苷元。 microbial survival and biotransformation of isoflavone glycosides to isoflavone aglycones in soymilk by Lactobacillus. 已发布 PubMed:大豆异黄酮合酶基因过表达的转基因番茄植株中异黄酮苷元的积累 Accumulation of isoflavone genistin in transgenic tomato plants overexpressing a soybean isoflavone synthase gene. 已发布 PubMed:副乳乳酸菌单一或混合培养发酵豆浆中异黄酮苷的水解。 Hydrolysis of isoflavone glucosides in soymilk fermented with single or mixed cultures of Lactobacillus paraplantarum KM, 魏斯氏菌33 Weissella sp. 33, 肠球菌球菌35分离自 。 and Enterococcus faecium 35 isolated from humans. 已发布 PubMed:对乳杆菌对豆浆中异黄酮糖苷向糖苷类生物转化的影响 Effect of lactulose on biotransformation of isoflavone glycosides to aglycones in soymilk by lactobacilli. 已发布 PubMed:彪马是大豆异黄酮染料木黄酮的新型靶标，但对于染料木黄酮诱导的细胞命运测定是必不可少的。 Puma is a novel target of soy isoflavone genistein but is dispensable for genistein-induced cell fate determination. 已发布 PubMed:撤销 WITHDRAWN: Genistin和依普黄酮 ipriflavone的组合可防止乳腺肿瘤发生并调节脂质分布。 已发布 PubMed:嗜热拟青霉细胞外切葡聚糖酶活性和转糖基化的热稳定细胞外β-葡糖苷酶的表征。 Characterization of a thermostable extracellular beta-glucosidase with activities of exoglucanase and transglycosylation from Paecilomyces thermophila. 已发布 PubMed:克隆 Cloning, 表达 expression, 异黄酮糖苷水解枯草芽孢杆菌纳豆中的两个β-葡萄糖苷酶的合成和表征。 and characterization of two beta-glucosidases from isoflavone glycoside-hydrolyzing Bacillus subtilis natto. 已发布 PubMed:乳酸菌发酵后，豆浆中的异黄酮葡萄糖苷转化为糖苷配基。 Conversion of isoflavone glucosides to aglycones in soymilk by fermentation with lactic acid bacteria. 已发布 PubMed:两种不同光照条件下生长的大豆（大豆（美金）芽）中异黄酮浓度的比较。 Comparison of isoflavone concentrations in soybean (Glycine max (L.) Merrill) sprouts grown under two different light conditions. 已发布 PubMed:大豆婴儿配方食品中存在的异黄酮浓度可在体外抑制轮状 感染。 Isoflavones at concentrations present in soy infant formula inhibit rotavirus infection in vitro. 已发布 PubMed:溶剂对大豆异黄酮提取和hplc分析的影响以及异黄酮组成受作物季节的影响。 Solvent effects on extraction and HPLC analysis of soybean isoflavones and variations of isoflavone compositions as affected by crop season. 已发布 PubMed:雄性鸣禽中的饮食植物雌激素和光周期反应 Dietary phytoestrogens and photoperiodic response in a male songbird, 黑眼睛的junco（junco Hyemalis hyemalis）。 已发布 PubMed:短双歧杆菌对发酵大豆异黄酮的抗肥胖作用。 Anti-obesity activities of fermented soygerm isoflavones by Bifidobacterium breve. 已发布 PubMed:植物雌激素对正在发育的女性 系统的破坏 Disruption of the developing female reproductive system by phytoestrogens: 以染料木黄酮为例。 genistein as an example. 已发布 PubMed:大豆异黄酮在大鼠中的生物利用度 Bioavailability of soy isoflavones in rats Part I: 准确的方法学研究性别和异黄酮来源的应用。 application of accurate methodology for studying the effects of gender and source of isoflavones. 已发布 PubMed:综述影响大豆异黄酮在 体内生物利用度的因素。 Review of the factors affecting bioavailability of soy isoflavones in humans. 已发布 PubMed:来自马来西亚农村和城市 口的脐带血中植物雌激素水平的测定。 Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations. 已发布 PubMed: 肠道来源的双歧杆菌种对普通豆类（菜豆）黄酮苷进行生物转化。 Biotransformation of common bean (Phaseolus vulgaris L.) flavonoid glycosides by bifidobacterium species from human intestinal origin. 已发布 PubMed:在老年雌性大鼠中，日粮中添加大豆异黄酮后，雌激素反应增强，雌激素反应也增强。 Enhanced estrogenic responses and sensitivity to azoxymethane following dietary soy isoflavone supplementation in older female rats. 已发布 PubMed:在自由移动的未麻醉大鼠的门静脉中测量的染料木黄酮及其苷苷染料木苷的生物利用度。 Bioavailability of genistein and its glycoside genistin as measured in the portal vein of freely moving unanesthetized rats. 已发布 PubMed:和ph值对染料木素和大豆苷异黄酮结合形式的影响。 Heat and pH effects on the conjugated forms of genistin and daidzin isoflavones. 已发布 PubMed:液相色谱/质谱联用光电二极管阵列检测技术对大鼠血浆中异黄酮及其代谢产物进行定量分析的一种准确且可重现的方法。 An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection. 已发布 PubMed:三种不同引发剂对大豆植物的施用对大豆种子中几种异黄酮浓度的影响 Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds. 已发布 PubMed:水溶性染料木黄酮苷异黄酮上调抗氧化剂金属硫蛋白的表达并清除自由基。 Water-soluble genistin glycoside isoflavones up-regulate antioxidant metallothionein expression and scavenge free radicals. 已发布 PubMed:尽管没有与已知异黄酮合酶的任何同源物，但在拟南芥中仍存在异黄酮。 Isoflavonoids are present in Arabidopsis thaliana despite the absence of any homologue to known isoflavonoid synthases. 已发布 PubMed:各种丝状真菌制备的黑豆曲中异黄酮异构体的分布特征 Distribution profiles of isoflavone isomers in black bean kojis prepared with various filamentous fungi. 已发布 PubMed:五种大豆（最大甘氨酸）基因型中的异黄酮水平通过植物色素介导的光照处理而改变。 Isoflavone levels in five soybean (Glycine max) genotypes are altered by phytochrome-mediated light treatments. 已发布 PubMed:大豆加工会影响去 的balb / c小鼠的代谢和膳食异黄酮的处置。 Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized BALB/c mice. 已发布 PubMed:化合物对大豆抗龋齿性的抵抗力重要吗？ Are chemical compounds important for soybean resistance to Anticarsia gemmatalis? 已发布 PubMed:超快速高效液相色谱/质谱法从生物样品中超临界流体萃取异黄酮。 Supercritical fluid extraction of isoflavones from biological samples with ultra-fast high-performance liquid chromatography/mass spectrometry. 已发布 PubMed:染料木苷的糖基化通过酶促修饰成环状葡聚糖的可溶性包合物形式。 Glycosylation of genistin into soluble inclusion complex form of cyclic glucans by enzymatic modification. 已发布 PubMed:快速柱高效液相色谱-二极管阵列检测器对大豆和大豆中异黄酮苷元和糖苷分布的评价 Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector. 已发布 PubMed:大豆异黄酮缓释制剂在健康的绝经后妇女中的药代动力学。 Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women. 已发布 PubMed:温度的影响 Effect of temperature, 二氧化碳升高 elevated carbon dioxide, 种子发育过程中的干旱和干旱对受控环境中生长的矮化大豆[glycine max（l。）merrill]异黄酮含量的影响。 and drought during seed development on the isoflavone content of dwarf soybean [Glycine max (L.) Merrill] grown in controlled environments. 已发布 PubMed:大豆异黄酮的抗癌治疗潜力 Anticancer therapeutic potential of soy isoflavone, 金雀异黄素。 genistein. 已发布 PubMed:phloridzin改善了genistin在离体大鼠小肠中的吸收。 Phloridzin improves absorption of genistin in isolated rat small intestine. 已发布 PubMed:葛根提取物抑制了自由饮水和饮酒的p鼠的自愿饮酒和戒酒症状。 Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol. 已发布 PubMed:稳定表达 雌激素受体α和β的快速酵母雌激素生物测定 Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, 和绿荧光蛋白 and green fluorescent protein: 比较具有两种受体类型的不同化合物。 a comparison of different compounds with both receptor types. 已发布 PubMed:通过曲酶提取物预处理豆浆可增强豆腐异黄酮的回收率。 Enhancement of tofu isoflavone recovery by pretreatment of soy milk with koji enzyme extract. 已发布 PubMed:大豆婴儿配方食品中存在的染料木黄酮浓度会导致g2 / m细胞周期停滞，从而抑制caco-2bbe细胞增殖。 Genistein at a concentration present in soy infant formula inhibits Caco-2BBe cell proliferation by causing G2/M cell cycle arrest. 已发布 PubMed:使用各种分离的灌肠段在大鼠中摄入染料木黄酮及其糖苷。 Intestinal uptake of genistein and its glycoside in the rat using various isolated perfused gut segments. 已发布 PubMed:大豆加工会影响雌激素依赖性乳腺癌肿瘤的生长。 Soy processing influences growth of estrogen-dependent breast cancer tumors. 已发布 PubMed:剂量和糖基化对金雀异黄素向鹌鹑蛋转移的影响。 Effects of dose and glycosylation on the transfer of genistein into the eggs of the Japanese quail (Coturnix japonica). 已发布 PubMed:水豆比对豆腐中异黄酮含量和组成的影响 Effect of water-to-bean ratio on the contents and compositions of isoflavones in tofu. 已发布 PubMed:内生细菌中异黄酮共轭物水解β-葡萄糖苷酶的纯化和表征。 Purification and characterization of an isoflavone-conjugates-hydrolyzing beta-glucosidase from endophytic bacterium. 已发布 PubMed:高效液相色谱-库仑法检测同时测定大鼠血清中的异黄酮和双酚a Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection. 已发布 PubMed:发酵谷物产品 Fermented grain products, 生产 production, 特性和对健康的好处。 properties and benefits to health. 已发布 PubMed: 肠道细菌在体外对大豆异黄酮苷苷的合成代谢及益生元的作用。 Metabolism of the soybean isoflavone glycoside genistin in vitro by human gut bacteria and the effect of prebiotics. 已发布 PubMed:雌激素和饮食中植物雌激素对 肠样caco-2细胞经上皮钙转运的影响。 The effect of oestrogen and dietary phyto-oestrogens on transepithelial calcium transport in human intestinal-like Caco-2 cells. 已发布 PubMed:高温和环境温度下储存的豆浆中异黄酮的稳定性。 Stability of isoflavones in soy milk stored at elevated and ambient temperatures. 已发布 PubMed:评估含有植物雌激素的豆类提取物的雌激素作用。 Evaluation of the estrogenic effects of legume extracts containing phytoestrogens. 已发布 PubMed:[转基因大豆和非转基因大豆中大豆皂苷和异黄酮含量的比较]。 [Comparison of soyasaponin and isoflavone contents between genetically modified (GM) and non-GM soybeans]. 已发布 PubMed: doenjang doenjang（韩国发酵的豆浆）及其活性化合物的抗突变作用。 已发布 PubMed:即食大豆婴儿配方食品中异黄酮的含量测定。 Determination of isoflavones in ready-to-feed soy-based infant formula. 已发布 PubMed:在线自动管内固相微萃取-高效液相色谱法测定大豆食品中的大豆苷元和染料木黄酮 Determination of daidzein and genistein in soybean foods by automated on-line in-tube solid-phase microextraction coupled to high-performance liquid chromatography. 已发布 PubMed:韩国某些李物种的体外抗氧化活性 In vitro antioxidant activity of some selected Prunus species in Korea. 已发布 PubMed:异黄酮 Isoflavone, 草甘膦 glyphosate, 草甘膦处理过的种子中的氨基酸和氨基甲基膦酸水平 and aminomethylphosphonic acid levels in seeds of glyphosate-treated, 抗草甘膦大豆。 glyphosate-resistant soybean. 已发布 PubMed:组成 Composition, 红细胞摄取 red blood cell uptake, 商业葛根和大豆制品中提取的植物雌激素的蛋白和血清蛋白结合。 and serum protein binding of phytoestrogens extracted from commercial kudzu-root and soy preparations. 已发布 PubMed:大豆苷的稳定性 Stabilities of daidzin, 甘氨酸 glycitin, genistin, 加热过程中生成衍生物。 and generation of derivatives during heating. 已发布 PubMed:异黄酮对原始264.7细胞和phix174 dna中一氧化氮或过氧亚硝酸盐介导的dna损伤的抑制作用。 Inhibitory effects of isoflavones on nitric oxide- or peroxynitrite-mediated DNA damage in RAW 264.7 cells and phiX174 DNA. 已发布 PubMed:谷物中黄豆苷元和染料木素的含量。 Daidzein and genistein content of cereals. 已发布 PubMed:低植物雌激素饮食用于内分泌干扰物研究。 Phytoestrogen-low diet for endocrine disruptor studies. 已发布 PubMed:英国的高大豆和低大豆异黄酮糖苷配基和糖缀合物含量营养研究中使用的食品。 Isoflavone aglycon and glucoconjugate content of high- and low-soy U.K. foods used in nutritional studies. 已发布 PubMed:异黄酮对过氧亚硝酸盐介导的低密度脂蛋白氧化的抑制作用。 Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation. 已发布 PubMed: 和大鼠肠道菌群比较染料木素的新陈代谢 Comparative metabolism of genistin by human and rat gut microflora: 检测和鉴定新陈代谢的最终产物。 detection and identification of the end-products of metabolism. 已发布 PubMed:萃取法测定大豆和含有大豆的精选食品中的异黄酮 Determination of isoflavones in soy and selected foods containing soy by extraction, 皂化 saponification, 和液相色谱 and liquid chromatography: 合作学习。 collaborative study. 已发布 PubMed:饮食中的染料木黄酮刺激雌激素依赖性乳腺癌肿瘤的生长，与染料木黄酮相似。 Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein. 已发布 PubMed:大豆曲制备过程中的异黄酮转化以及随后的味o发酵，辅以乙醇和氯化钠。 Isoflavone transformation during soybean koji preparation and subsequent miso fermentation supplemented with ethanol and NaCl. 已发布 PubMed:高速逆流色谱法分离大豆中的异黄酮成分 Preparative separation of isoflavone components in soybeans using high-speed counter-current chromatography. 已发布 PubMed:金雀异黄素概况的变化 Changes in the profile of genistein, 黄豆苷元 daidzein, 及其在豆腐热处理过程中的结合物。 and their conjugates during thermal processing of tofu. 已发布 PubMed:大豆产品中异黄酮的Maldi-tof MS分析。 MALDI-TOF MS analysis of isoflavones in soy products. 已发布 PubMed:影响类黄酮吸收的因素。 Factors affecting flavonoids absorption. 已发布 PubMed:蔬菜中黄豆苷元和染料木黄酮的含量。 Daidzein and genistein contents of vegetables. 已发布 PubMed:大豆异黄酮和类胡萝卜素在未成熟大豆种子（毛豆类）加工过程中的保留和变化。 Retention and changes of soy isoflavones and carotenoids in immature soybean seeds (Edamame) during processing. 已发布 PubMed:水果和坚果中的大豆苷元和染料木黄酮含量。 Daidzein and genistein content of fruits and nuts. 已发布 PubMed:大豆和大豆食品中异黄酮含量的测定以及日本日摄入量中异黄酮的估算。 Determination of the levels of isoflavonoids in soybeans and soy-derived foods and estimation of isoflavonoids in the Japanese daily intake. 已发布 PubMed:泡盛曲霉发酵的豆粕增加了小鼠肝微粒体的细胞色素p-450含量。 Soybean meal fermented by Aspergillus awamori increases the cytochrome P-450 content of the liver microsomes of mice. 已发布 PubMed: lc-esi-ms研究了红三叶草（trifolium pratense）的类黄酮糖苷丙二酸酯。 已发布 PubMed:来自酸樱桃（樱桃李）的抗氧化剂多酚。 Antioxidant polyphenols from tart cherries (Prunus cerasus). 已发布 PubMed:含异黄酮的大豆植物化学提取物（spe）的抗氧化作用和潜在的抗糖尿病特性。 Antioxidant action and potential antidiabetic properties of an isoflavonoid-containing soyabean phytochemical extract (SPE). 已发布 PubMed:从商业大豆加工副产品中分离出的化学级分的抗突变活性。 Antimutagenic activity of chemical fractions isolated from a commercial soybean processing by-product. 已发布 PubMed:大豆黄酮和染料木黄酮从大鼠胃中吸收，但不是它们的糖苷。 Daidzein and genistein but not their glucosides are absorbed from the rat stomach. 已发布 PubMed:异黄酮介导的酪氨酸激酶抑制 Isoflavone-mediated inhibition of tyrosine kinase: 一种新颖的抗炎方法。 a novel antiinflammatory approach. 已发布 PubMed:大豆异黄酮分析 Soy isoflavone analysis: 质量控制和新的内部标准。 quality control and a new internal standard. 已发布 PubMed:食品中大豆苷元和染料木黄酮的提取和定量。 Extraction and quantification of daidzein and genistein in food. 已发布 PubMed:豆渣曲的体内抗氧化活性 In vivo antioxidant activity of Okara Koji, 发酵的豆渣 a fermented okara, 由米曲霉。 by Aspergillus oryzae. 已发布 PubMed:大豆和大豆制品中染料木黄酮和染料木素的定量分析。 Quantification of genistein and genistin in soybeans and soybean products. 已发布 PubMed:大豆异黄酮染料木黄酮在体外而非体内诱导小鼠脾细胞中微核形成。 Induction of micronucleus formation in mouse splenocytes by the soy isoflavone genistein in vitro but not in vivo. 已发布 PubMed:染料木苷和大豆苷对小鼠的雌激素作用。 Oestrogenic potency of genistin and daidzin in mice. 已发布 PubMed:cd-1小鼠对大豆异黄酮染料木黄酮的雌激素反应 Oestrogenic response of the CD-1 mouse to the soya-bean isoflavones genistein, 染料木苷和大豆苷。 genistin and daidzin.

笔记 Notes: 大豆异黄酮苷 glycoside of soy bean isoflavone, 根蒂斯坦。存在于大豆食品中。潜在的营养价值。分离。来自樱桃李（野樱桃） gentistein. Present in soy foods. Potential nutriceutical. Isol. from Prunus avium (wild cherry) 染料木素是几种已知的异黄酮之一。染料木素存在于大豆等多种植物和草药中。 Genistin is one of several known isoflavones. Genistin is found in a number of plants and herbs like soy.