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类别 Category:natural substances and extractives
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 沸点 Boiling Point: | 305.00 to 307.00 °C. @ 760.00 mm 汞 Hg
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| 蒸汽压力 Vapor Pressure: | 0.001000 毫米汞柱 mm汞 Hg @ 25.00 °C. (估 est) |
| 闪点 Flash Point: | 279.00 °F. tcc TCC ( 137.22 °C. )
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| logp（o / w） logP (o/w): | 5.369（估 est） |
| 溶于 Soluble in: |
| | 水 water, 0.1005 mg / l @ 25°C（估 est） |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | natural substances and extractives |
| 呋喃二烯用量建议 Recommendation for furanodiene usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 呋喃二烯风味使用水平的推荐值 Recommendation for furanodiene flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
| | (5z (5Z,9z）-3 9Z)-3,6,10-trimethyl-4,7,8,11-tetrahydrocyclodeca[b]furan |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| pubchem（cid） Pubchem (cid): | 5317424 |
| pubchem（sid） Pubchem (sid): | 135154531 |
其他资料 Other Information:
潜在 有力的 Potential 搅拌机 Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, food, 其他） other): note
同义词 Synonyms:
| (z (Z,e）-8 E)-8,12- | epoxygermacra-1(10),4,7,11-四烯 11-tetraene | | (5E,9z）-4 9Z)-4,7,8,11- | tetrahydro-3,6,10-trimethyl cyclodeca(b)furan | | (5z (5Z,9z）-3 9Z)-3,6,10- | trimethyl-4,7,8,11-tetrahydrocyclodeca[b]furan |
文章 Articles:
| 已发布 PubMed:姜黄根状茎的细胞毒性成分。 Cytotoxic Constituents from the Rhizomes of Curcuma zedoaria. |
| 已发布 PubMed:呋喃二烯 Furanodiene, 天然的小分子抑制转移性乳腺癌细胞在体外的迁移和侵袭。 a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro. |
| 已发布 PubMed:[跨过caco-2 / ht29-mtx共培养细胞的plga纳米颗粒的运输]。 [Transport of PLGA nanoparticles across caco-2/HT29-MTX co-cultured cells]. |
| 已发布 PubMed:呋喃二烯对95 d肺癌细胞的影响 Effects of furanodiene on 95-D lung cancer cells: 凋亡 apoptosis, 自噬和g1期细胞周期停滞。 autophagy and G1 phase cell cycle arrest. |
| 已发布 PubMed:高效液相色谱-电喷雾电离质谱和核磁共振波谱表征大鼠体内呋喃二烯的体内和体外代谢产物。 Characterization of in vivo and in vitro metabolites of furanodiene in rats by high performance liquid chromatography-electrospray ionization mass spectrometry and nuclear magnetic resonance spectra. |
| 已发布 PubMed:固定剂量的混合杀菌素的影响 Impact of fixed-dose combination of germacrone, 姜黄酮 curdione, 和呋喃二烯对乳腺癌细胞的增殖作用。 and furanodiene on breast cancer cell proliferation. |
| 已发布 PubMed:不含姜黄素的姜黄具有抗炎和抗癌活性 Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: 鉴定姜黄的新成分。 Identification of novel components of turmeric. |
| 已发布 PubMed:促性腺激素刺激垂体腺苷酸环化酶激活多肽（pacap）信使核糖核酸在大鼠 中的作用以及pacap作为卵泡存活因子的作用。 GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum. |
| 已发布 PubMed:2溴1 2-Bromo-1,6,6-三甲基-6 6-trimethyl-6,7,8,9-四氢菲并[1 9-tetra-hydro-phenanthro[1,2-b]呋喃10 2-b]furan-10,11-dione。 11-dione. |
| 已发布 PubMed:快速灵敏的hplc-apci-ms / ms方法测定呋喃二烯w / o / w多种乳剂在大鼠体内的药代动力学和组织分布。 Pharmacokinetics and tissue distribution of furanodiene W/O/W multiple emulsions in rats by a fast and sensitive HPLC-APCI-MS/MS method. |
| 已发布 PubMed:呋喃二烯通过改变95-d肺癌细胞的细胞周期和整联蛋白信号传导，与紫杉醇具有协同抗增殖活性。 Furanodiene presents synergistic anti-proliferative activity with paclitaxel via altering cell cycle and integrin signaling in 95-D lung cancer cells. |
| 已发布 PubMed:被忽视的植物sm草中精油和呋喃倍半萜的体外生物活性（api科）。 In vitro biological activity of essential oils and isolated furanosesquiterpenes from the neglected vegetable Smyrnium olusatrum L. (Apiaceae). |
| 已发布 PubMed:用一个参考标准同时测定姜黄温郁金中草药和相关产品中的多种倍半萜。 Simultaneous determination of multiple sesquiterpenes in Curcuma wenyujin herbal medicines and related products with one single reference standard. |
| 已发布 PubMed:红毛刺中的呋喃丹6-6抑制nf-κb信号传导并减弱lps诱导的橙花炎症。 Furanodien-6-one from Commiphora erythraea inhibits the NF-κB signalling and attenuates LPS-induced neuroinflammation. |
| 已发布 PubMed:呋喃二烯可诱导内质网应激，并在肺癌细胞中具有抗增殖活性。 Furanodiene induces endoplasmic reticulum stress and presents antiproliferative activities in lung cancer cells. |
| 已发布 PubMed:呋喃二烯 Furanodiene, 天然产品 a natural product, 在体外和体内均抑制乳腺癌的生长。 inhibits breast cancer growth both in vitro and in vivo. |
| 已发布 PubMed:乳化电动色谱法分析姜黄根茎中的挥发性成分 Analysis of volatile components in Curcuma rhizome by microemulsion electrokinetic chromatography. |
| 已发布 PubMed:姜黄中萜类化合物的抗癌特性-综述 Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review. |
| 已发布 PubMed:呋喃二烯以不依赖pparγ的方式增强他莫昔芬诱导的时代阳性乳腺癌细胞的生长抑制活性。 Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPARγ independent manner. |
| 已发布 PubMed:液相色谱/串联质谱法测定大鼠血浆中呋喃二烯的灵敏方法及其在药代动力学研究中的应用 A sensitive method for determination of furanodiene in rat plasma using liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. |
| 已发布 PubMed:呋喃二烯对腐殖酸体外和体内斑马鱼的抗血管生成作用。 Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. |
| 已发布 PubMed:姜黄提取物对乳腺癌细胞的抗肿瘤潜力。 Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells. |
| 已发布 PubMed:使用tlc生物自显影分析法和gc-ms分析对四种姜黄中的自由基清除活性和倍半萜进行表征。 Free radical scavenging activity and characterization of sesquiterpenoids in four species of Curcuma using a TLC bioautography assay and GC-MS analysis. |
| 已发布 PubMed:高效液相色谱法测定姜黄油及其相关注射剂中的六种成分 [HPLC determination of six components in zedoary turmeric oil and its related injections]. |
| 已发布 PubMed:呋喃二烯的潜在抗癌活性 Potential anti-cancer activities of Furanodiene, 姜黄温榆金中的倍半萜。 a Sesquiterpene from Curcuma wenyujin. |
| 已发布 PubMed:呋喃二烯通过激活tnfr1信号通路诱导hl60白血病细胞凋亡。 Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway. |
| 已发布 PubMed:姜黄的倍半萜。 Sesquiterpenes from Curcuma comosa. |
| 已发布 PubMed:呋喃二烯通过 肝癌细胞中的mapk信号传导和线粒体caspase途径诱导g2 / m细胞周期停滞和凋亡。 Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells. |
| 已发布 PubMed:加压液相萃取和高效液相色谱法同时测定三种姜黄根茎中的11种特征成分。 Simultaneous determination of 11 characteristic components in three species of Curcuma rhizomes using pressurized liquid extraction and high-performance liquid chromatography. |
| 已发布 PubMed:姜黄的抗炎倍半萜。 Anti-inflammatory sesquiterpenes from Curcuma zedoaria. |
| 已发布 PubMed:基于分析物的分辨率和稳定性优化gc-ms条件，以便同时测定三种姜黄根茎中的九种倍半萜。 Optimization of GC-MS conditions based on resolution and stability of analytes for simultaneous determination of nine sesquiterpenoids in three species of Curcuma rhizomes. |
| 已发布 PubMed:加压液相萃取和气相色谱-质谱联用技术鉴定和定量分析三种姜黄根茎中的11种倍半萜。 Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry. |
| 已发布 PubMed:没药油性口香糖树脂中某些成分的刺激性。 Irritant potential of some constituents from oleo-gum-resin of Commiphora myrrha. |
| 已发布 PubMed:药用食品。 xxix。莪术中倍半萜和姜黄素对d-半乳糖胺/脂多糖或肿瘤坏死因子-α诱导的肝损伤的有效保护作用。 Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha. |
| 已发布 PubMed:sm草精油成分。 Essential oil composition of smyrnium olusatrum. |
| 已发布 PubMed:呋喃二烯的鉴定与定量测定 Identification and quantitative determination of furanodiene, 热敏化合物 a heat-sensitive compound, 在13c-nmr的精油中 in essential oil by 13C-NMR. |
| 已发布 PubMed:g草属加勒比珊瑚中挥发性代谢物的化学变异性。 Chemical variability of the volatile metabolites from the Caribbean corals of the genus Gorgonia. |
| 已发布 PubMed:局麻药 Local anaesthetic, 没药的倍半萜的抗菌和抗真菌特性。 antibacterial and antifungal properties of sesquiterpenes from myrrh. |
| 已发布 PubMed:莪术中倍半萜对d-半乳糖胺/脂多糖诱导的肝损伤的抑制作用及作用机理 Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury. |
| 已发布 PubMed:醋酸尤尼克霉素的吡唑啉衍生物。 A pyrazoline derivative of eunicin acetate. |
| 已发布 PubMed: commiphora 吉多蒂 guidotti精油的成分。 |
| 已发布 PubMed:[没药的精油的成分]。 [Constituents of the essential oil of myrrh]. |
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3D/INCHI