山楂酸 maslinic acid
齐墩果酸12-en-28-油酸 olean-12-en-28-oic acid, 2,3-二羟基 3-dihydroxy-, (2α alpha , 3beta beta)-

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    4373-41-5山梨酸> 98% 4373-41-5 Maslinic acid >98%
    山楂酸是在多种天然来源中发现的五环三萜。它具有广泛的生物活性 Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, 如抗肿瘤 such as antitumor, 抗糖尿病 antidiabetic, antioxidant, 心脏保护 cardioprotective, 橙花保护 neuroprotective, 抗寄生虫和促进生长。 antiparasitic and growth-stimulating.
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    gl6116山梨酸 GL6116 Maslinic acid
CAS号 CAS Number: 4373-41-5Picture of molecule3D/INCHI
FDA UNII:E233J88OHQ
nikkaji网站 Nikkaji Web:J22.580K
MDL :mfcd00049293 MFCD00049293
XlogP3-AA:6.50(est) 6.50 (est)
分子量 Molecular Weight:472.70936000
式 Formula:c30 h48 o4 C30 H48 O4
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:antioxidants
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
沸点 Boiling Point: 570.00 °C. @ 760.00 mm 汞 Hg (est)
闪点 Flash Point: 595.00 °F. tcc TCC ( 312.60 °C. ) (est)
logp(o / w) logP (o/w): 7.870(est) 7.870 (est)
溶于 Soluble in:
 水 water, 0.00396 mg / l @ 25°C(est) 0.00396 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: antioxidants
皮肤调理 skin conditioning
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
山梨酸> 98% Maslinic acid >98%
气味 Odor: characteristic
采用 Use: 山楂酸是在多种天然来源中发现的五环三萜。它具有广泛的生物活性 Maslinic acid is a pentacyclic triterpene found in a variety of natural sources. It exerts a wide range of biological activities, 如抗肿瘤 such as antitumor, 抗糖尿病 antidiabetic, antioxidant, 心脏保护 cardioprotective, 橙花保护 neuroprotective, 抗寄生虫和促进生长。 antiparasitic and growth-stimulating.
碳合蛋白 Carbosynth
仅供实验/研究使用。 For experimental / research use only.
克拉酸 Crategolic acid
Glentham Life Sciences
山楂酸 maslinic acid
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
山楂酸 maslinic acid
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
山楂酸≥98%(hplc) Maslinic Acid ≥98% (HPLC)
西安健威生物技术有限公司 Xian Healthway Biotech
山楂酸 maslinic acid
味道 Flavor: characteristic
Hawthorn (山龟 Crataegus 种类 species ) is a small 树 tree or 灌木 shrub and a 会员 member of the 玫瑰 rose 家庭 family. it It was 挂 hung 过度 over the 门口 doorway in the 中间 Middle 年龄 Ages to 避免 prevent the 条目 entry of 邪恶 evil spirits. By the 早 early 1800s, 美国医生认识到这种草药的药用特性,并开始将其用于治疗循环系统疾病和呼吸系统疾病。 American doctors recognized the herb's medicinal properties and began using it to treat circulatory disorders and respiratory illnesses.
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: antioxidants
推荐使用山楂酸水平 Recommendation for maslinic acid usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐使用山楂酸调味剂的水平 Recommendation for maslinic acid flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
Epi系统 EPI System: 视图 View
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :73659
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
(4as (4aS, 6a 6ar , 6a 6as , 6b 6br , 8a 8ar ,10r 10R,11r 11R,12ar 12aR,14bs)-10 14bS)-10,11-二羟基-2 11-dihydroxy-2,2,6a 6a,6b 6b,9,9,12a-七甲基-1 12a-heptamethyl-1,3,4,5,6,6a 6a,7,8,8a 8a,10,11,12,13,14b-十四氢吡啶烯-4a-羧酸 14b-tetradecahydropicene-4a-carboxylic acid
chemidplus Chemidplus:0004373415
 
参考资料 References:
 (4as (4aS, 6a 6ar , 6a 6as , 6b 6br , 8a 8ar ,10r 10R,11r 11R,12ar 12aR,14bs)-10 14bS)-10,11-二羟基-2 11-dihydroxy-2,2,6a 6a,6b 6b,9,9,12a-七甲基-1 12a-heptamethyl-1,3,4,5,6,6a 6a,7,8,8a 8a,10,11,12,13,14b-十四氢吡啶烯-4a-羧酸 14b-tetradecahydropicene-4a-carboxylic acid
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):73659
pubchem(sid) Pubchem (sid):135033519
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
KEGG (GenomeNet):C16939
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB02392
食物 FooDB:FDB013041
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None Found
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 丁香水果 clove fruit
搜索 Search Trop Picture
 丁香油 clove oil
搜索 Search Trop Picture
 丁香种子 clove seed
搜索 Search Trop Picture
 番石榴果 guava fruit
搜索 Search Trop Picture
 番石榴叶 guava leaf
搜索 Search Trop Picture
 番石榴叶油 guava leaf oil
搜索 Search Trop Picture
 叶 loquat leaf
搜索 Search Trop Picture
 橄榄 olive
搜索 Search Trop Picture
 橄榄果 olive fruit
搜索 Search Trop Picture
 橄榄壳 olive hull husk
搜索 Search Trop Picture
 橄榄色皮肤蜡 olive skin wax
搜索 Search Trop Picture
 石榴 pomegranate
搜索 Search Trop Picture
 石榴花 pomegranate flower
搜索 Search Trop Picture
 鼠尾草 sage leaf
搜索 Search Trop Picture
 咸味冬季咸味植物 savory winter savory plant
搜索 Search Trop Picture
 
同义词 Synonyms:
 官僚的 crategolic acid
(4as (4aS, 6a 6ar , 6a 6as , 6b 6br , 8a 8ar ,10r 10R,11r 11R,12ar 12aR,14bs)-10 14bS)-10,11-dihydroxy-2,2,6a 6a,6b 6b,9,9,12a-七甲基-1 12a-heptamethyl-1,3,4,5,6,6a 6a,7,8,8a 8a,10,11,12,13,14b-十四氢吡啶烯-4a-羧酸 14b-tetradecahydropicene-4a-carboxylic acid
 马斯利 maslic acid
 阳刚酸 maslinicacid
 齐墩果酸12-en-28-油酸 olean-12-en-28-oic acid, 2,3-二羟基 3-dihydroxy-,
 齐墩果酸12-en-28-油酸 olean-12-en-28-oic acid, 2,3-二羟基 3-dihydroxy-, (2α alpha , 3beta beta)-
 

文章 Articles:

已发布 PubMed:在高氧和低氧条件下,山楂酸诱导a549肺癌细胞的线粒体凋亡并抑制hif-1α表达。 Maslinic Acid Induces Mitochondrial Apoptosis and Suppresses HIF-1α Expression in A549 Lung Cancer Cells under Normoxic and Hypoxic Conditions.
已发布 PubMed:橄榄叶提取物中三萜酸对利什曼原虫前鞭毛体阶段线粒体膜电位的体外影响 In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp.
已发布 PubMed:酸对小鼠醇性急性肝损伤的保护作用 Protective effects of maslinic acid against alcohol-induced acute liver injury in mice.
已发布 PubMed:三叶草果皮的抗菌型齐墩烷型三萜类化合物。 Antibacterial oleanane-type triterpenoids from pericarps of Akebia trifoliata.
已发布 PubMed:山楂酸 maslinic acid, 从橄榄中提取的天然植物抗毒素型三萜烯-一种有前途的保健食品吗? a natural phytoalexin-type triterpene from olives--a promising nutraceutical?
已发布 PubMed:山楂酸激活心脏癌中线粒体依赖性凋亡途径。 Maslinic acid activates mitochondria-dependent apoptotic pathway in cardiac carcinoma.
已发布 PubMed:山梨酸群体药代动力学 Population pharmacokinetics of maslinic acid, 橄榄中的三萜 a triterpene from olives, 大鼠静脉和口服给药后。 after intravenous and oral administration in rats.
已发布 PubMed:齐墩果酸和山梨酸双功能衍生物的固相文库合成及其对三种癌细胞系的细胞毒性 Solid-phase library synthesis of bi-functional derivatives of oleanolic and maslinic acids and their cytotoxicity on three cancer cell lines.
已发布 PubMed:菊苣属的芳香植物和药用植物的植物化学和生物活性。 Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae).
已发布 PubMed:山楂酸通过增强胰岛素信号传导途径和抑制糖原磷酸化酶来调节糖原代谢。 Maslinic acid modulates glycogen metabolism by enhancing the insulin signaling pathway and inhibiting glycogen phosphorylase.
已发布 PubMed:山梨酸通过激活p38 mapk信号通路诱导膀胱癌细胞凋亡。 Maslinic acid induced apoptosis in bladder cancer cells through activating p38 MAPK signaling pathway.
已发布 PubMed:山楂酸通过akt / nrf2 / ho-1途径保护血管平滑肌细胞免受氧化应激。 Maslinic acid protects vascular smooth muscle cells from oxidative stress through Akt/Nrf2/HO-1 pathway.
已发布 PubMed:齐墩果酸和山楂酸通过抑制多药耐药蛋白mrp-1使软组织肉瘤细胞对阿霉素敏感 Oleanolic and maslinic acid sensitize soft tissue sarcoma cells to doxorubicin by inhibiting the multidrug resistance protein MRP-1, 但不是p-糖蛋白。 but not P-glycoprotein.
已发布 PubMed:从橄榄油工业废料中半合成酰化三萜烯,用于开发抗癌和抗艾滋 药物。 Semi-synthesis of acylated triterpenes from olive-oil industry wastes for the development of anticancer and anti-HIV agents.
已发布 PubMed:山楂酸类似物的膜破坏活性。 Membrane damaging activity of a maslinic acid analog.
已发布 PubMed:从汉藤藤黄树脂中分离出四个新的三萜。 Four new triterpenoids isolated from the resin of Garcinia hanburyi.
已发布 PubMed:山楂酸对肝脏的抗氧化作用 Antioxidant effects of maslinic acid in livers, 链脲佐菌素诱导的糖尿病大鼠的心脏和肾脏 hearts and kidneys of streptozotocin-induced diabetic rats: 对肾功能的影响。 effects on kidney function.
已发布 PubMed:橄榄中主要三萜的生物活性 Bioactive properties of the main triterpenes found in olives, 初榨橄榄油 virgin olive oil, 和油橄榄的叶子。 and leaves of Olea europaea.
已发布 PubMed:糖激发后,芳香合酶衍生的三萜对链脲佐菌素诱导的糖尿病大鼠餐后血糖的影响。 Effects of Syzygium aromaticum-derived triterpenes on postprandial blood glucose in streptozotocin-induced diabetic rats following carbohydrate challenge.
已发布 PubMed:对山楂酸细胞毒性和选择性衍生物。 Towards cytotoxic and selective derivatives of maslinic acid.
已发布 PubMed:山楂酸酯和酰胺触发 肿瘤细胞的凋亡,并改变它们在c-28处的取代方式。 Esters and amides of maslinic acid trigger apoptosis in human tumor cells and alter their mode of action with respect to the substitution pattern at C-28.
已发布 PubMed:山楂酸及其体外抗肿瘤作用。 Maslinic acid and its in vitro anti-neoplastic effects.
已发布 PubMed:液相色谱-质谱法测定血浆中的山梨酸 Liquid chromatography-mass spectrometry determination in plasma of maslinic acid, 一种来自油橄榄的生物活性化合物。 a bioactive compound from Olea europaea L.
已发布 PubMed:对p53缺失的caco-2腺癌细胞中三萜类山梨酸外在凋亡靶标的抗肿瘤活性。 Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells.
已发布 PubMed: 对黑麦草酸和山楂酸生物转化。 Biotransformation of oleanolic and maslinic acids by Rhizomucor miehei.
已发布 PubMed:橄榄树(油橄榄)果实和叶子上的五环三萜类化合物的时间过程。绘画和简历成熟期间的科内佐罗。 Time course of pentacyclic triterpenoids from fruits and leaves of olive tree (Olea europaea L.) cv. Picual and cv. Cornezuelo during ripening.
已发布 PubMed:[化学成分的紫花粳稻变种。甘草酸及其抗互补活性]。 [Chemical constituents of Rabdosia japonica var. glaucocalyx and their anti-complementary activity].
已发布 PubMed:山楂酸止痛和止痛作用 Antiallodynic and analgesic effects of maslinic acid, 一种来自油橄榄的五环三萜。 a pentacyclic triterpenoid from Olea europaea.
已发布 PubMed:[山楂酸预处理对氧-葡萄糖剥夺所致的胚胎大鼠皮层橙花元损伤的保护作用]。 [Protective effect of maslinic acid preconditioning against oxygen-glucose deprivation- induced injuries in embryonic rat cortical neurons].
已发布 PubMed:富山梨酸饮食可通过转录组和代谢组学重编程减少apc(min / +)小鼠肠道肿瘤的发生。 Maslinic acid-enriched diet decreases intestinal tumorigenesis in Apc(Min/+) mice through transcriptomic and metabolomic reprogramming.
已发布 PubMed:山楂酸 maslinic acid, 三萜类抗肿瘤药 a triterpenic anti-tumoural agent, 干扰ht29 结肠癌细胞中的细胞骨架蛋白表达。 interferes with cytoskeleton protein expression in HT29 human colon-cancer cells.
已发布 PubMed:白血病病原菌来源的三萜类化合物在 白血病细胞系中的抗增殖活性和凋亡诱导 Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines.
已发布 PubMed:奇异果花和果实的化学成分。 Chemical constituents of flowers and fruits of Rabdosia excisa.
已发布 PubMed:评估山楂酸安全性 Assessment of the safety of maslinic acid, 一种来自油橄榄的生物活性化合物。 a bioactive compound from Olea europaea L.
已发布 PubMed:同时测定玉米花中的七种主要三萜。 lc-ms方法确定安德烈斯 Simultaneous determination of seven major triterpenoids in Pyrola decorata H. Andres by LC-MS method.
已发布 PubMed:[来自缬草已知的非蒽醌成分]。 [Non-anthraquinones constituents from the roots of Knoxia valerianoides].
已发布 PubMed:一种简单的gc-ms方法筛选白蛋白 A simple GC-MS method for the screening of betulinic, 腐蚀性的 corosolic, maslinic, 商业植物药中的齐墩果酸和熊果酸含量,用作食品补充成分。 oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.
已发布 PubMed:山梨酸测定 Determination of maslinic acid, 橄榄中的五环三萜 a pentacyclic triterpene from olives, 高效液相色谱法测定大鼠血浆中 in rat plasma by high-performance liquid chromatography.
已发布 PubMed:中华接骨木的化学成分 [Chemical constituents from Sambucus chinensis].
已发布 PubMed:山楂酸可保护异丙肾上腺素对苦参wistar大鼠的心脏毒性。 Maslinic acid protects against isoproterenol-induced cardiotoxicity in albino Wistar rats.
已发布 PubMed:生物利用度 Bioavailability, 分配 Distribution, 和选定的三萜对小鼠的抗氧化作用。 and antioxidative effects of selected triterpenes in mice.
已发布 PubMed:酸对 b淋巴母细胞中pma诱导的蛋白激酶c的抑制作用。 Suppressive effect of maslinic acid on PMA-induced protein kinase C in human B-lymphoblastoid cells.
已发布 PubMed:初榨橄榄油中生物活性化合物调节动脉粥样硬化发展的功效。 Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development.
已发布 PubMed:山楂酸抑制du145 前列腺癌细胞的转移能力 Maslinic acid inhibits the metastatic capacity of DU145 human prostate cancer cells: 可能通过低氧诱导因子1α信号介导。 possible mediation via hypoxia-inducible factor-1α signalling.
已发布 PubMed:丹参中的新萜烯。和丹参。在约旦变得越来越野。 New terpenes from Salvia palaestina Benth. and Salvia syriaca L. growing wild in Jordan.
已发布 PubMed:非甾体三萜类化合物是油橄榄的主要成分。 Nonsterol Triterpenoids as Major Constituents of Olea europaea.
已发布 PubMed:一种来自莲ne的根茎的新三萜。 A new triterpenoid from the rhizomes of Nelumbo nucifera.
已发布 PubMed:[女贞子果实中的三萜类化合物的研究]。 [Study on the triterpenoids from the fruits of Ligustrum lucidum].
已发布 PubMed:来自红树林的异常异构体角鲨内酯 Unusual isomeric corniculatolides from mangrove, 埃及盾。 Aegiceras corniculatum.
已发布 PubMed:建立测定橄榄果中三萜酸有效方法 Towards an efficient protocol for the determination of triterpenic acids in olive fruit: 干燥和提取方法的比较研究。 a comparative study of drying and extraction methods.
已发布 PubMed: [swertia Swertia 历史性的 hispidicalyx的化学成分]。
已发布 PubMed:通过三萜类化合物靶向炎症途径来预防和治疗癌症。 Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer.
已发布 PubMed:[关于拟南芥茎的化学成分]。 [Chemical constituents about the stem of Rabdosia excisa].
已发布 PubMed:山楂酸衍生物在鼠b16f10黑素瘤细胞中诱导明显的凋亡。 Maslinic acid derivatives induce significant apoptosis in b16f10 murine melanoma cells.
已发布 PubMed:山楂酸抗炎作用 Anti-inflammatory effects of maslinic acid, 天然三萜 a natural triterpene, 通过抑制核因子κb在培养的皮质星形胶质细胞中的表达。 in cultured cortical astrocytes via suppression of nuclear factor-kappa B.
已发布 PubMed:蛋白质组学分析raji细胞对山梨酸治疗的分子反应。 Proteomic analysis of the molecular response of Raji cells to maslinic acid treatment.
已发布 PubMed:山楂酸 maslinic acid, 一种来自油橄榄的天然三萜类化合物 a natural triterpenoid compound from Olea europaea, 保护皮质橙花元免受氧葡萄糖剥夺引起的损伤。 protects cortical neurons against oxygen-glucose deprivation-induced injury.
已发布 PubMed:[关于泡桐的化学成分的研究]。 [Studies on the chemical constituents from the leave of Paulownia tomentosa].
已发布 PubMed:山楂酸 maslinic acid, 糖原磷酸化酶的天然抑制剂 a natural inhibitor of glycogen phosphorylase, 通过上调glt-1来减轻高血糖大鼠的脑缺血损伤。 reduces cerebral ischemic injury in hyperglycemic rats by GLT-1 up-regulation.
已发布 PubMed: 金头鲷(sparus 光环 aurata)肝脏中的蛋白质组学,以阐明摄取山楂酸诱导的细胞反应。
已发布 PubMed:果渣提取物对高脂血症的作用。 Effect of olive pomace extracts on hyperlipidaemia.
已发布 PubMed:2-(2-(蒽-10-基)-1h-菲咯啉[9]鉴别和测定食品中的羧酸[9] Identification and determination of carboxylic acids in food samples using 2-(2-(anthracen-10-yl)-1H-phenanthro[9,hplc用fld和apci / ms作为标记试剂的4-甲基苯磺酸10-d]咪唑-1-基)乙基酯(apiets)。 10-d]imidazol-1-yl)ethyl 4-methylbenzenesulfonate (APIETS) as labeling reagent by HPLC with FLD and APCI/MS.
已发布 PubMed:山楂酸作为抗疟疾天然化合物的多靶点活性。 Multi-targeted activity of maslinic acid as an antimalarial natural compound.
已发布 PubMed:苯那嗪的单次和亚急性局部和全身毒性研究。 Simultaneous qualitative and quantitative analysis of triterpenic acids, hplc-pda-ms / elsd分析了两个吉普斯物种的叶片中的皂苷和类黄酮。 saponins and flavonoids in the leaves of two Ziziphus species by HPLC-PDA-MS/ELSD.
已发布 PubMed:天然三萜山楂酸通过jnk-p53依赖性机制诱导ht29结肠癌细胞凋亡。 The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism.
已发布 PubMed:山楂酸寄生虫作用。 ii。致死性约氏疟原虫感染小鼠的存活率提高和免疫保护。 Parasitostatic effect of maslinic acid. II. Survival increase and immune protection in lethal Plasmodium yoelii-infected mice.
已发布 PubMed:液体粘液的三萜和三萜皂苷 [Triterpenoids and triterpenoid saponins of Viscum liquidambaricolum].
已发布 PubMed:山楂酸寄生虫作用。一世。恶性疟原虫红细胞内阶段的生长停滞。 Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stages.
已发布 PubMed:柱前荧光衍生化新hplc方法的开发,可快速 Development of a new HPLC method with precolumn fluorescent derivatization for rapid, 水果中三萜酸选择性和灵敏检测。 selective and sensitive detection of triterpenic acids in fruits.
已发布 PubMed:桔梗中的三萜皂苷。 Triterpenoid saponins from Symplocos lancifolia.
已发布 PubMed:山楂酸通过ca2 +诱发的p38信号通路诱导唾液腺腺样囊性癌细胞的凋亡。 Maslinic acid induces apoptosis in salivary gland adenoid cystic carcinoma cells by Ca2+-evoked p38 signaling pathway.
已发布 PubMed:蓝花car的茎皮中的苯丙烷。 Phenylpropanoids from the stem bark of Jacaranda mimosaefolia.
已发布 PubMed:三种三萜酸在 肝癌细胞中的抗血管生成潜力。 Antiangiogenic potential of three triterpenic acids in human liver cancer cells.
已发布 PubMed:抗氧化剂 Antioxidant, 抗增殖 antiproliferative, 橄榄皮中发现的五环三萜类化合物对MCF-7 类乳腺癌细胞的凋亡和促凋亡能力及其对脱氧核糖核酸 DNA损伤的影响。
已发布 PubMed:星形细胞谷氨酸转运蛋白依赖的橙花保护对谷氨酸毒性 Astrocytic glutamate transporter-dependent neuroprotection against glutamate toxicity: 对山楂酸体外研究。 an in vitro study of maslinic acid.
已发布 PubMed:[关于榕果化学成分的研究]。 [Studies on the chemical constituents of Ficus microcarpa].
已发布 PubMed:五环三萜和橙花酰胺通过no / cgmp途径参与离体大鼠主动脉环,介导cinkowskii绒毛的血管舒张活性。 Pentacyclic triterpenoids and ceramide mediate the vasorelaxant activity of Vitex cienkowskii via involvement of NO/cGMP pathway in isolated rat aortic rings.
已发布 PubMed:山楂酸可通过调节Rankl介导的nf-κb和mapk信号通路来抑制破骨细胞生成并防止 切除术引起的骨质流失。 Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways.
已发布 PubMed:使用 体肠道微粒体从蔓越莓(大果痘苗)中分离和鉴定肠道cyp3a抑制剂。 Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes.
已发布 PubMed:药理学操作脑糖原分解术作为治疗脑缺血的方法。 Pharmacological manipulation of brain glycogenolysis as a therapeutic approach to cerebral ischemia.
已发布 PubMed:cos的茎中具有清除自由基活性的化学成分。 Chemical constituents with free-radical-scavenging activities from the stem of Microcos paniculata.
已发布 PubMed:橄榄果实和叶子上的五环三萜。 Pentacyclic triterpenoids from olive fruit and leaf.
已发布 PubMed:马来酸化学预防作用 Cancer chemopreventive activity of maslinic acid: 抑制rax细胞中cox-2表达并抑制nf-κb和ap-1活化。 suppression of COX-2 expression and inhibition of NF-κB and AP-1 activation in Raji cells.
已发布 PubMed:五环三萜二醇和酸抗氧化和抗动脉粥样硬化活性。 Antioxidant and antiatherogenic activities of pentacyclic triterpenic diols and acids.
已发布 PubMed:山楂酸对鸡的艾​​美球虫感染的抗球虫活性。 Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens.
已发布 PubMed:提取自锦葵属的植物甾醇和山楂酸对raji细胞中ebv早期抗原表达的化学预防作用。 Chemopreventive properties of phytosterols and maslinic acid extracted from Coleus tuberosus in inhibiting the expression of EBV early-antigen in Raji cells.
已发布 PubMed:五环三萜的作用 Action of a pentacyclic triterpenoid, 山楂酸 maslinic acid, 反对弓形虫。 against Toxoplasma gondii.
已发布 PubMed:山梨酸通过抑制nf-kappab信号通路增强了肿瘤坏死因子α的抗肿瘤活性。 Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway.
已发布 PubMed:欧洲油橄榄叶中的两个新的类蛇药苷。 Two new secoiridoid glycosides from the leaves of Olea europaea L.
已发布 PubMed:由橄榄油行业固体废物中的萜烯制得的具有附加值的生物活性化合物。 Bioactive compounds with added value prepared from terpenes contained in solid wastes from the olive oil industry.
已发布 PubMed:天然三萜烯化合物a环脱氧的不同途径。 Different pathways for the deoxygenation of the A-ring of natural triterpene compounds.
已发布 PubMed:[妮维耶勃氏根的化学成分]。 [Chemical constituents of roots of Boehmeria nivea].
已发布 PubMed:不同季节采集的粳稻叶片中三萜酸测定 [Determination of triterpenoid acids in leaves of Eriobotrya japonica collected at in different seasons].
已发布 PubMed:酪氨酸磷酸酶1b的新型抑制剂杂环取代的山梨酸衍生物的合成及生物学评价。 Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.
已发布 PubMed:转化的青花球藻细胞悬浮培养,产生镇静的非弗雷德莱恩斯。 Transformed cell suspension culture of Galphimia glauca producing sedative nor-friedelanes.
已发布 PubMed:水果的品质以及橄榄叶和石头的添加会影响原味橄榄油中三萜的含量。 Fruit quality and olive leaf and stone addition affect Picual virgin olive oil triterpenic content.
已发布 PubMed:四十个橄榄品种的初榨橄榄油的三萜含量和化学计量分析。 Triterpenic content and chemometric analysis of virgin olive oils from forty olive cultivars.
已发布 PubMed:山梨酸作用 Effects of maslinic acid, 天然三萜 a natural triterpene, 对培养的皮质星形胶质细胞糖原代谢的影响。 on glycogen metabolism in cultured cortical astrocytes.
已发布 PubMed:芒草化学成分的研究 [Chemical constituents from herbs of Swertia mileensis].
已发布 PubMed: 血清白蛋白与反式阿魏酸山梨酸新型结合研究。 Novel binding studies of human serum albumin with trans-feruloyl maslinic acid.
已发布 PubMed:[关于lo叶中的三萜的研究]。 [Studies on the triterpenes from loquat leaf (Eriobotrya japonica)].
已发布 PubMed:含氨基酸和肽的山楂酸衍生物的固溶和固相合成及其抗HIV活性。 Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides.
已发布 PubMed:从紫花苜蓿叶中分离出的三萜酸作为α-葡萄糖苷酶抑制剂。 Triterpene acids isolated from Lagerstroemia speciosa leaves as alpha-glucosidase inhibitors.
已发布 PubMed:夏枯草的三萜酸紫丁香及其体外细胞毒性活性。 Triterpenoic acids of Prunella vulgaris var. lilacina and their cytotoxic activities in vitro.
已发布 PubMed:载脂蛋白e决定了小鼠饮食中山楂酸肝转录谱。 Apolipoprotein E determines the hepatic transcriptional profile of dietary maslinic acid in mice.
已发布 PubMed:药用花。 xxiii。新的taraxastane型三萜 Medicinal flowers. XXIII. New taraxastane-type triterpene, 芥酸 punicanolic acid, 石榴花中的肿瘤坏死因子-α抑制活性。 with tumor necrosis factor-alpha inhibitory activity from the flowers of Punica granatum.
已发布 PubMed:溴乙酸实用合成 Practical synthesis of bredemolic acid, 糖原磷酸化酶的天然抑制剂。 a natural inhibitor of glycogen phosphorylase.
已发布 PubMed:山楂酸 maslinic acid, 来自油橄榄的天然三萜。 a natural triterpene from Olea europaea L., 通过线粒体凋亡途径诱导ht29 结肠癌细胞凋亡。 induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway.
已发布 PubMed:抗炎和抗氧化活性及非洲platostoma p。的成分。美丽 Anti-inflammatory and antioxidant activities and constituents of Platostoma africanum P. Beauv.
已发布 PubMed:对大鼠食用紫丁香(桃金娘科)叶片的胃保护活性的评价 Evaluation of gastroprotective activity of Plinia edulis (Vell.) Sobral (Myrtaceae) leaves in rats.
已发布 PubMed:天然存在的五环三萜作为糖原磷酸化酶的抑制剂 Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: 合成 synthesis, 构效关系 structure-activity relationships, 和X射线晶体学研究。 and X-ray crystallographic studies.
已发布 PubMed:马来酸和齐墩果酸抗增殖和凋亡诱导作用 Antiproliferative and apoptosis-inducing effects of maslinic and oleanolic acids, 橄榄中的两个五环三萜 two pentacyclic triterpenes from olives, 在ht-29结肠癌细胞上。 on HT-29 colon cancer cells.
已发布 PubMed:杜氏菊科植物全草的醛糖还原酶和蛋白质糖基化抑制原理。 Aldose-reductase- and protein-glycation-inhibitory principles from the whole plant of Duchesnea chrysantha.
已发布 PubMed:生物活性指导下的罗汉果活性成分的分离以及hplc对抗坏血酸定量分析。 Bioactivity-guided isolation of the active compounds from Rosa nutkana and quantitative analysis of ascorbic acid by HPLC.
已发布 PubMed:山楂酸可降低kk-ay小鼠的血糖。 Maslinic acid reduces blood glucose in KK-Ay mice.
已发布 PubMed: 饮食中添加的山楂酸可提高虹鳟(oncorhynchus 我的吻 mykiss)白肌肉的生长和蛋白质转化率。
已发布 PubMed:山茱us茎中化合物的抗弹性蛋白酶和清除自由基的活性。 Antielastase and free radical scavenging activities of compounds from the stems of Cornus kousa.
已发布 PubMed:酪氨酸酶抑制性五环三萜和杜鹃花甲醇提取物的镇痛和解痉活性。 Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum.
已发布 PubMed: 豆(junellia aspera aspera)(马鞭草科)中的齐墩果烷对dna拓扑异构酶i的抑制和对 类癌细胞系的生长抑制。
已发布 PubMed:三萜 三萜 Tri萜类化合物 terpenoids 隔离的 isolated from 苹果 apple 果皮 peels 有 have 有力的 potent 抗增殖 antiproliferative 活动 activity and 可以 may be 部分地 partially 负责任的 responsible for 苹果 apple's 抗癌药 anti癌症 cancer 活动 activity.
已发布 PubMed:油茶的细胞悬浮培养生产三萜酸。 Production of triterpene acids by cell suspension cultures of Olea europaea.
已发布 PubMed:酸性三萜烯通过调节活性氧的积累而损害星形细胞瘤细胞系的生长和存活。 Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation.
已发布 PubMed:区域选择性环palpalladation甲基的远程羟基化。庚酸部分合成-a。 Remote hydroxylation of methyl groups by regioselective cyclopalladation. Partial synthesis of hyptatic acid-A.
已发布 PubMed:油橄榄果实发育过程中三萜的形成。 Formation of triterpenoids throughout Olea europaea fruit ontogeny.
已发布 PubMed:细胞因子硬脂醇聚醚的调节橄榄果渣油中的五环三萜类化合物在 单核细胞中产生的离子 Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.
已发布 PubMed:[来自中国委陵菜的三萜]。 [Triterpenes from herb of Potentilla chinesis].
已发布 PubMed:沙棘的三萜类化合物l。及其抑制一氧化氮产生和清除dpph自由基的活性。 Triterpenoids from Hippophae rhamnoides L. and their nitric oxide production-inhibitory and DPPH radical-scavenging activities.
已发布 PubMed:四味子中的新糖苷及其细胞毒性活性。 New glycosides from Tetracentron sinense and their cytotoxic activity.
已发布 PubMed: (2α alpha , 3beta beta)-2 ,3-二羟基油酸酯-12-en-28-油酸 3-dihydroxyolean-12-en-28-oic acid, 一种来自欧洲油菜的新天然三萜 a new natural triterpene from Olea europea, 在结肠腺癌细胞中选择性诱导半胱天冬酶 caspase依赖性凋亡。
已发布 PubMed:橄榄果提取物抑制ht-29 结肠癌细胞的增殖并诱导其凋亡。 Olive fruit extracts inhibit proliferation and induce apoptosis in HT-29 human colon cancer cells.
已发布 PubMed: 山楂酸作为饲料添加剂,可刺激虹鳟鱼(onchorhynchus 我的吻 mykiss)的生长和肝蛋白转化率。
已发布 PubMed: 次生代谢物来自durio zibethinus zibethinus和durio 库特吉斯 kutejensis的木皮。
已发布 PubMed:石榴花的成分。 Constituents of the flowers of Punica granatum.
已发布 PubMed:白藜芦醇中的二萜抑制前列腺素诱导的收缩。 Diterpenes from Leucas aspera inhibiting prostaglandin-induced contractions.
已发布 PubMed:一种有效的化学方法,可从其异构山梨酸中分离出皮质酸。 An efficient chemical method for separation of corsolic acid from its isomeric maslinic acid.
已发布 PubMed:从榆树的根皮中分离出新的三萜。 New triterpenoids isolated from the root bark of Ulmus pumila L.
已发布 PubMed:在青冈的液体培养毛状根中产生三萜类化合物。 Production of triterpenoids in liquid-cultivated hairy roots of Galphimia glauca.
已发布 PubMed:三萜 Triterpenic compounds from "奥鲁霍 orujo" 橄榄 olive oil 引出 elicit 血管舒张 vasorelaxation in 主动脉 aorta from 自发地 spontaneously 高血压 hypertensive 老鼠 rats.
已发布 PubMed:渣油橄榄油中山楂酸对受刺激的鼠巨噬细胞氧化应激和细胞因子产生的抑制作用。 Supressive effect of maslinic acid from pomace olive oil on oxidative stress and cytokine production in stimulated murine macrophages.
已发布 PubMed:五环三萜。第2Pentacyclic triterpenes. Part 2: 糖原磷酸化酶抑制剂的山楂酸衍生物的合成及生物学评价。 Synthesis and biological evaluation of maslinic acid derivatives as glycogen phosphorylase inhibitors.
已发布 PubMed:五环三萜。第1Pentacyclic triterpenes. Part 1: 天然存在的五环三萜作为糖原磷酸化酶的新型抑制剂的第一个例子。 the first examples of naturally occurring pentacyclic triterpenes as a new class of inhibitors of glycogen phosphorylases.
已发布 PubMed:桔梗花中的三萜类化合物。舒姆作为 类的酰基可可 Triterpenoids from the flower of Campsis grandiflora K. Schum. as human acyl-CoA: 胆固醇酰基转移酶抑制剂。 cholesterol acyltransferase inhibitors.
已发布 PubMed:金合欢果实化学成分的研究 [Studies on chemical constituents in fruit of Rubus chingii].
已发布 PubMed: 食蟹小食根虫(incarvillea 公司 Incarvillea arguta arguta)的根源发现了新型橙花酰胺和新型葡萄糖橙花酰胺。
已发布 PubMed:枣果实中三萜的抗补体活性 Anti-complementary activity of triterpenoides from fruits of Zizyphus jujuba.
已发布 PubMed:木瓜木瓜的抗肿瘤促进成分及其在jb6小鼠表皮细胞中的活性。 Antitumor-promoting constituents from Chaenomeles sinensis KOEHNE and their activities in JB6 mouse epidermal cells.
已发布 PubMed:山楂酸抗氧化活性 Antioxidant activity of maslinic acid, 从油橄榄中获得的三萜衍生物。 a triterpene derivative obtained from Olea europaea.
已发布 PubMed:环氧化物 Epoxides, 环状亚硫酸盐 cyclic sulfites, 和天然五环三萜类化合物的硫酸盐 and sulfate from natural pentacyclic triterpenoids: 理论计算和化学转化。 theoretical calculations and chemical transformations.
已发布 PubMed:毛io的生物活性三萜烯的生产。 Production of bioactive triterpenes by Eriobotrya japonica calli.
已发布 PubMed: 兰帕亚 Lampaya Hieronymi hieronymi schum的植物化学研究和抗炎特性。前摩尔登克。
已发布 PubMed:紫花苜蓿的抗菌三萜类化合物。 Antimicrobial triterpenoids from Licania heteromorpha.
已发布 PubMed:中间果麦草茎皮中的细胞毒性三萜类化合物。 Cytotoxic triterpenes from stem bark of Physocarpus intermedius.
已发布 PubMed:四倍体香叶茎皮中的两个糖苷。 Two glycosides from the stem bark of Tetracentron sinense.
已发布 PubMed:亮度盖亚那(谷仓)burret中的类黄酮和类萜。 Flavonoids and terpenoids from Luma gayana (Barn.) Burret.
已发布 PubMed:得自四叶猴的dna聚合酶β抑制剂。 DNA polymerase beta inhibitors from Tetracera boiviniana.
已发布 PubMed:锦葵中的抗艾滋 三萜烯酸。 Anti-HIV triterpene acids from Geum japonicum.
已发布 PubMed:新的三萜衍生物的抗 活性。 Antiviral activity of new triterpenic derivatives.
已发布 PubMed:筛选对埃里希腹水肿瘤细胞中葡萄糖转运活性有影响的植物成分。 Screening of plant constituents for effect on glucose transport activity in Ehrlich ascites tumour cells.
已发布 PubMed:[关于a香根化学成分的研究]。 [Studies on the chemical constituents from roots of Agastache rugosa].
已发布 PubMed:甘蓝圆柏的三萜皂苷。 Triterpene saponins from Cylicodiscus gabunensis.
已发布 PubMed:来自中药的细胞毒性三萜 Cytotoxic triterpenes from a Chinese medicine, goreishi。 Goreishi.
 
笔记 Notes:
润滑和共同偿付收益。在头发护理中用作树脂增塑剂和上光剂。在彩色化妆品中有效的铺展和润湿剂。非常适合用于喷雾止汗剂,以减少“粉化”。在指甲油去除剂中用作超级脂肪剂。 isolated from the stem bark of physocarpus intermedius. Maslinic acid is a compound derived from dry olive-pomace oil (an olive skin wax) which is a byproduct of olive oil extraction. It is a member of the group of triterpenes known as oleananes.; Maslinic acid is a pentacyclic triterpene, 在橄榄果渣油(橄榄油果渣油)的非橙花酯馏分中发现 found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, 也 also known as "奥鲁霍 orujo" 橄榄 olive oil, 是精制果渣油和初榨橄榄油的混合物 is a blend of refined-pomace oil and virgin olive oil, 由cochem scs制备的护发素对纤维蛋白具有天然亲和力,因此在头发的表皮上形成保护性涂层。这种保护性涂层减少了头发的缠结,同时增强了湿梳理性和整体可管理性 fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, 4-甲氧基-2-甲基-黑醋栗酮黑醋栗硫醇甲氧基甲基丁烷硫醇4-甲氧基-2-甲基丁烷硫醇4-甲氧基-2-甲基丁烷-2-硫醇4-甲氧基-2-甲基-2-丁烷硫醇4-甲氧基-pg-4-甲氧基-2-甲基-2-巯基丁烷4-甲氧基-2-甲基丁烷-2-硫醇4-甲氧基-4-甲基丁烷-2-硫醇甲氧基甲基中的1%-2-丁烷硫醇4-甲氧基-2-甲基-2-丁烷硫醇丁烷硫醇甲氧基甲基丁硫醇 since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and 表征 characterise the 机制 机制 mechanisms 底层的 underlying the 双相的 biphasic 性质 nature of some 方面 aspects of the 发炎的 inflammatory 响应 response. (mid PMID: 17292619)
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