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类别 Category:antioxidant, bleaching, skin conditioning
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 溶于 Soluble in: |
| | 水 water, 9.591e + 005 mg / l @ 25°c（est） 9.591e+005 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
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| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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| 象形图 Pictogram | |
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| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
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未定 Not determined
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | antioxidant, bleaching, skin conditioning |
| 推荐的α-熊果素使用水平最高为 Recommendation for alpha-arbutin usage levels up to: | | | 不用于香水。 not for fragrance use.
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| 推荐的α-熊果素风味使用水平最高为 Recommendation for alpha-arbutin flavor usage levels up to: |
| | 不用于调味料。 not for flavor use.
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安全参考 Safety references:
参考资料 References:
| | (2R,3s 3S,4s 4S,5r 5R,6r）-2-（羟甲基）-6-（4-羟基苯氧基）恶烷-3 6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-三醇 5-triol |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| pubchem（cid） Pubchem (cid): | 158637 |
| pubchem（sid） Pubchem (sid): | 135114345 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| a-D- | glucopyranoside, 4-hydroxyphenyl | | (2R,3s 3S,4s 4S,5r 5R,6R)-2-( | hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-三醇 5-triol | | 4- | hydroxyphenyl a-d-吡喃葡萄糖苷 a-D-glucopyranoside | | 4- | hydroxyphenyl-alpha-d-吡喃葡萄糖苷 a-D-glucopyranoside |
文章 Articles:
| 已发布 PubMed:新型抗衰老护手霜的评估。 Assessment of a Novel Anti-Aging Hand Cream. |
| 已发布 PubMed:消费者安全科学委员会（sccs）的意见-有关在化妆品中使用α-熊果苷的安全性的意见。 Opinion of the Scientific Committee on Consumer safety (SCCS) - Opinion on the safety of the use of α-arbutin in cosmetic products. |
| 已发布 PubMed:α-和β-熊果苷的化学和酶稳定性的比较研究。 Comparative studies on the chemical and enzymatic stability of alpha- and beta-arbutin. |
| 已发布 PubMed:定量测定α-熊果苷 Quantitative Determination of α-Arbutin, β-熊果苷 β-Arbutin, 曲酸 Kojic Acid, 烟酰胺 Nicotinamide, 对苯二酚 Hydroquinone, 间苯二酚 Resorcinol, 4-甲氧基苯酚 4-Methoxyphenol, 4-乙氧基苯酚 4-Ethoxyphenol, hplc-uv的美白产品中的抗坏血酸和抗坏血酸。 and Ascorbic Acid from Skin Whitening Products by HPLC-UV. |
| 已发布 PubMed:α-熊果苷对蘑菇酪氨酸酶单酚酶和双酚酶活性的双重影响 Dual effects of alpha-arbutin on monophenolase and diphenolase activities of mushroom tyrosinase. |
| 已发布 PubMed:穿透深度 Penetration depth, 壳蛋白微泡超声处理小鼠超声后透皮α-熊果苷的浓度和效率。 concentration and efficiency of transdermal α-arbutin delivery after ultrasound treatment with albumin-shelled microbubbles in mice. |
| 已发布 PubMed:草莓花萼中的三萜类化合物及其对b16-f10小鼠黑素瘤细胞黑素生成的抑制作用。 Triterpenoids from Fragaria ananassa calyx and their inhibitory effects on melanogenesis in B16-F10 mouse melanoma cells. |
| 已发布 PubMed:黄单胞菌BT-112补料分批发酵中提高α-熊果苷产量的补料策略。 Feeding strategies for the enhanced production of α-arbutin in the fed-batch fermentation of Xanthomonas maltophilia BT-112. |
| 已发布 PubMed:重组大肠杆菌蔗糖磷酸化酶的性质及酶法合成α-熊果苷的研究 [Properties of sucrose phosphorylase from recombinant Escherichia coli and enzymatic synthesis of alpha-arbutin]. |
| 已发布 PubMed:大孔树脂吸附色谱法从黄单胞菌CGMC1243发酵液中分离α-熊果苷。 Isolation of α-arbutin from Xanthomonas CGMCC 1243 fermentation broth by macroporous resin adsorption chromatography. |
| 已发布 PubMed:高α-熊果苷生产菌株的筛选和发酵生产α-熊果苷。 Screening of high α-arbutin producing strains and production of α-arbutin by fermentation. |
| 已发布 PubMed:生物技术生产熊果素（α-和β-熊果苷） Biotechnological production of arbutins (α- and β-arbutins), 亮肤剂 skin-lightening agents, 及其衍生物。 and their derivatives. |
| 已发布 PubMed:对苯二酚高产酶促生物转化为α-熊果苷 High-yield enzymatic bioconversion of hydroquinone to α-arbutin, 强大的亮肤剂 a powerful skin lightening agent, 淀粉糖酶。 by amylosucrase. |
| 已发布 PubMed:鼠李糖蔗糖异构酶及其突变体可合成α-熊果苷。 Sucrose isomerase and its mutants from Erwinia rhapontici can synthesise α-arbutin. |
| 已发布 PubMed:豚鼠中α-熊果苷与对苯二胺和对苯二酚交叉反应的实验研究。 Experimental study on cross-reactivity of alpha-arbutin toward p-phenylenediamine and hydroquinone in guinea pigs. |
| 已发布 PubMed:medlite c6 q开关nd治疗难治性黄褐斑 Treatment of refractory melasma with the MedLite C6 Q-switched Nd:yag激光和alpha熊果苷 YAG laser and alpha arbutin: 前瞻性研究。 a prospective study. |
| 已发布 PubMed:[α-熊果苷的测定 [Determination of alpha-arbutin, 高效液相色谱法测定化妆品中的β-熊果苷和烟酰胺] beta-arbutin and niacinamide in cosmetics by high performance liquid chromatography]. |
| 已发布 PubMed:medlite c6 q-switch nd治疗难治性皮肤黄褐斑 Treatment of refractory dermal melasma with the MedLite C6 Q-switched Nd:yag激光 YAG laser: 两个案例报告。 two case reports. |
| 已发布 PubMed:使用表面锚定的转葡糖苷酶对大肠杆菌进行高细胞密度培养，用作α-熊果苷合成的全细胞生物催化剂。 High cell density cultivation of Escherichia coli with surface anchored transglucosidase for use as whole-cell biocatalyst for alpha-arbutin synthesis. |
| 已发布 PubMed:新型亮肤剂的调节作用 Modulating effects of a novel skin-lightening agent, α-硫辛酸衍生物 alpha-lipoic acid derivative, 通过形成多巴共轭产物来抑制黑素的产生。 on melanin production by the formation of DOPA conjugate products. |
| 已发布 PubMed:喜多单胞菌的冰核蛋白在大肠杆菌表面显示葡萄糖苷酶及其在对苯二酚糖基化中的应用。 Surface display of transglucosidase on Escherichia coli by using the ice nucleation protein of Xanthomonas campestris and its application in glucosylation of hydroquinone. |
| 已发布 PubMed:路易斯酸催化的新合成α-熊果苷的方法是用对苯二酚对四-邻-苄基-α-d-吡喃葡萄糖基三氯乙酰亚氨酸进行选择性糖基化。 A new synthesis of alpha-arbutin via Lewis acid catalyzed selective glycosylation of tetra-O-benzyl-alpha-D-glucopyranosyl trichloroacetimidate with hydroquinone. |
| 已发布 PubMed:α-熊果苷-α-糖苷的合成及其对 酪氨酸酶的抑制作用。 Syntheses of alpha-arbutin-alpha-glycosides and their inhibitory effects on human tyrosinase. |
| 已发布 PubMed:利用桔梗黄单胞菌wu-9701的冻干细胞通过对苯二酚的α-端基异构体选择性糖基化酶促合成α-熊果苷。 Enzymatic synthesis of alpha-arbutin by alpha-anomer-selective glucosylation of hydroquinone using lyophilized cells of Xanthomonas campestris WU-9701. |
| 已发布 PubMed:α-熊果苷对培养的 黑素瘤细胞和三维 体皮肤模型中黑素合成的抑制作用。 Inhibitory effects of alpha-arbutin on melanin synthesis in cultured human melanoma cells and a three-dimensional human skin model. |
| 已发布 PubMed:合成熊果苷-糖苷的合成及其与α-熊果苷和熊果苷对 酪氨酸酶抑制作用的比较。 Syntheses of arbutin-alpha-glycosides and a comparison of their inhibitory effects with those of alpha-arbutin and arbutin on human tyrosinase. |
| 已发布 PubMed:和熊果苷对蘑菇和小鼠黑素瘤酪氨酸酶活性的影响 Effects of alpha- and beta-arbutin on activity of tyrosinases from mushroom and mouse melanoma. |
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