|
类别 Category:cosmetic ingredient for skin conditioning
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 化验 Assay: | 95.00至100.00 95.00 to 100.00
|
| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 溶于 Soluble in: |
| | 水 water, 1.559e + 004 mg / l @ 25°c（est） 1.559e+004 mg/L @ 25 °C (est) |
感官特性 Organoleptic Properties:
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
| 首选sds SDS : 视图 View |
| |
| 危害识别 Hazards identification |
| |
| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
| |
| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
|
未定 Not determined
|
| 皮肤毒性 Dermal Toxicity: |
|
未定 Not determined
|
| 吸入毒性 Inhalation Toxicity: |
|
未定 Not determined
|
使用安全信息 Safety in Use Information:
| 类别 Category: | cosmetic ingredient for skin conditioning |
| 推荐使用杜鹃花的使用水平 Recommendation for rhododendrol usage levels up to: | | | 不用于香水。 not for fragrance use.
|
| |
安全参考 Safety references:
参考资料 References:
| | 4-（3-羟丁基）苯酚 4-(3-hydroxybutyl)phenol |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 69617-84-1 |
| pubchem（cid） Pubchem (cid): | 97790 |
| pubchem（sid） Pubchem (sid): | 135053777 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, 餐饮 food, 其他） other): note
同义词 Synonyms:
| | 苯丙醇 benzenepropanol, 4-hydroxy-alpha-methyl- | | 4-(3- | hydroxybutyl)phenol | | 4-(p- | hydroxyphenyl)-2-butanol | | 4-(p- | hydroxyphenyl)butan-2-ol | | | 覆盆子酮 raspberry ketone alcohol |
文章 Articles:
| 已发布 PubMed:谷胱甘肽维持对于杜鹃花黑素细胞的存活至关重要。 Glutathione maintenance is crucial for survival of melanocytes after exposure to rhododendrol. |
| 已发布 PubMed:酪氨酸酶存在下杜鹃醇对nf-κb抑制作用对黑素细胞的影响。 The effect of rhododendrol inhibition of NF-κB on melanocytes in the presence of tyrosinase. |
| 已发布 PubMed:杜鹃花诱发的白皮病的分光光度分析使用新型多光谱相机。 The spectrophotometrical analysis of rhododendrol-induced leucoderma using a novel multispectral camera. |
| 已发布 PubMed:富含黄烷醇的荔枝果实提取物对黑素生物合成和活性氧的生物化学作用。 Biochemical effects of the flavanol-rich lychee fruit extract on the melanin biosynthesis and reactive oxygen species. |
| 已发布 PubMed:杜鹃醇和覆盆子酮通过反应性氧物种依赖性的gadd45激活而损害黑素细胞的正常增殖。 Rhododenol and raspberry ketone impair the normal proliferation of melanocytes through reactive oxygen species-dependent activation of GADD45. |
| 已发布 PubMed:nad（p）h脱氢酶 NAD(P)H dehydrogenase, 醌1（nqo1） quinone 1 (NQO1), 保护产生黑素的细胞免受杜鹃花的细胞毒性。 protects melanin-producing cells from cytotoxicity of rhododendrol. |
| 已发布 PubMed:[由化学物质引起的白皮病 [Leukoderma caused by chemicals: 4-烷基/芳基取代的苯酚和杜鹃花醇诱导的黑素细胞损失的机制] mechanisms underlying 4-alkyl/aryl-substituted phenols- and rhododendrol-induced melanocyte loss]. |
| 已发布 PubMed:杜鹃花诱导明串球菌病患者对酪氨酸酶衍生自肽的t细胞应答 T-Cell Responses to Tyrosinase-Derived Self-Peptides in Patients with Leukoderma Induced by Rhododendrol: 靶向黑素瘤的免疫治疗的意义。 Implications for Immunotherapy Targeting Melanoma. |
| 已发布 PubMed:丰富的咸味动物脂肪，带有柑橘和香菜，如nuancemosciano Rhododenol-induced leukoderma in a mouse model mimicking Japanese skin. |
| 已发布 PubMed:五种色素的不同作用 Different effects of five depigmentary compounds, rhododendrol, 覆盆子酮 raspberry ketone, 单苯甲酮 monobenzone, 芸香酚和ap736对 表皮黑素细胞的黑素生成和活力的影响。 rucinol and AP736 on melanogenesis and viability of human epidermal melanocytes. |
| 已发布 PubMed:杜鹃醇糖苷作为立体特异性酪氨酸酶抑制剂。 Rhododendrol glycosides as stereospecific tyrosinase inhibitors. |
| 已发布 PubMed:杜鹃及其代谢产物对黑素细胞生长的影响 Effects of rhododendrol and its metabolic products on melanocytic cell growth. |
| 已发布 PubMed:一种方便的筛选方法，可将酚类皮肤增白酪氨酸酶抑制剂与诱导白皮病的酚区分开。 A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols. |
| 已发布 PubMed:由非杜鹃花亮肤剂引起的杜鹃花诱发的白皮病并伴有过敏性接触性皮炎 Rhododendrol-induced leukoderma accompanied by allergic contact dermatitis caused by a non-rhododendrol skin-lightening agent, 5,5'-dipropylbiphenyl-2,2'-diol. |
| 已发布 PubMed:具有促氧化作用的酚类化合物诱导的黑素细胞特异性细胞毒性机制 The mechanism of melanocytes-specific cytotoxicity induced by phenol compounds having a prooxidant effect, 与白斑病的外观有关。 relating to the appearance of leukoderma. |
| 已发布 PubMed:杜鹃烯醇诱发的白皮病患者可能参与ccr4 + cd8 + t细胞和血浆ccl22和ccl17升高。 Possible involvement of CCR4+ CD8+ T cells and elevated plasma CCL22 and CCL17 in patients with rhododenol-induced leukoderma. |
| 已发布 PubMed:生化 Biochemical, 细胞学的 cytological, 杜鹃醇诱导的白皮病的免疫及免疫机制 and immunological mechanisms of rhododendrol-induced leukoderma. |
| 已发布 PubMed:杜鹃醇诱导的白皮病患者的黑素细胞特异性细胞毒性t淋巴细胞。 Melanocyte-specific cytotoxic T lymphocytes in patients with rhododendrol-induced leukoderma. |
| 已发布 PubMed:酪氨酸酶催化杜鹃花（rd）在b16黑素瘤细胞中的代谢 Tyrosinase-catalyzed metabolism of rhododendrol (RD) in B16 melanoma cells: -pheo黑素 melanin的生产以及与硫醇蛋白的共价结合。 |
| 已发布 PubMed:4-（4-羟氧基苯基）-2-丁醇（杜鹃醇）激活黑素细胞中的自噬-溶酶体途径 4-(4-hydroroxyphenyl)-2-butanol (rhododendrol) activates the autophagy-lysosome pathway in melanocytes: 对杜鹃花引起的白皮病机理的见解。 insights into the mechanisms of rhododendrol-induced leukoderma. |
| 已发布 PubMed:杜鹃醇诱发的白皮病患者的免疫病理学和超微结构皮肤分析。 An immune pathological and ultrastructural skin analysis for rhododenol-induced leukoderma patients. |
| 已发布 PubMed: [杜鹃花P已 haseochrysum var。的酚类化合物。凝集素]。 |
| 已发布 PubMed: 酪氨酸酶能够氧化杜鹃醇的两种对映体。 Human tyrosinase is able to oxidize both enantiomers of rhododendrol. |
| 已发布 PubMed:施用活性增白剂引起的色素沉着 Depigmentation caused by application of the active brightening material, rhododendrol, 在一定阈值下与酪氨酸酶活性有关。 is related to tyrosinase activity at a certain threshold. |
| 已发布 PubMed:酪氨酸酶催化的杜鹃醇的氧化反应生成2-甲基色烷-6 Tyrosinase-catalyzed oxidation of rhododendrol produces 2-methylchromane-6,7-二酮 7-dione, 推定的最终有毒代谢物 the putative ultimate toxic metabolite: 对黑素细胞毒性的影响。 implications for melanocyte toxicity. |
| 已发布 PubMed:杜鹃花 Rhododendrol, 脱色素的酚类化合物 a depigmentation-inducing phenolic compound, 通过酪氨酸酶依赖性机制发挥黑素细胞的细胞毒性。 exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism. |
| 已发布 PubMed:杜鹃醇糖苷的化学合成和酪氨酸酶抑制活性。 Chemical synthesis and tyrosinase inhibitory activity of rhododendrol glycosides. |
| 已发布 PubMed:杜鹃花 Rhododendrol, 一种止痛/消炎的芳基丁烷糖苷 an analgesic/anti-inflammatory arylbutanoid glycoside, 从金杜鹃的叶子。 from the leaves of Rhododendron aureum. |
| 已发布 PubMed:源自宏n的二苯醚型环状二芳基庚烷的成骨活性。 Osteogenic activity of diphenyl ether-type cyclic diarylheptanoids derived from Acer nikoense. |
| 已发布 PubMed:宏h皮中二芳基庚烷类和其他酚类化合物的黑素生成抑制和自由基清除活性。 Melanogenesis inhibitory and free radical scavenging activities of diarylheptanoids and other phenolic compounds from the bark of Acer nikoense. |
| 已发布 PubMed:（+）-杜鹃花和表杜鹃花素抑制体内活化的巨噬细胞的不产生。 (+)-rhododendrol and epi-rhododendrin suppress the NO production by activated macrophages in vivo. |
|
3D/INCHI