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类别 Category:flavoring agents
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
| 出现 Appearance: | 浅黄至琥珀透明液体（est） pale yellow to amber clear liquid (est) |
| 化验 Assay: | 97.00至100.00 97.00 to 100.00
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| 食品化学品法典列表 Food Chemicals Codex Listed: | No |
| 比重 Specific Gravity: | 1.00300 to 1.00900 @ 25.00 °C.
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| 磅每加仑-（est）。 Pounds per Gallon - (est).: | 8.346 to 8.396
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| 折光率 Refractive Index: | 1.51500 to 1.52000 @ 20.00 °C.
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| 沸点 Boiling Point: | 100.00 °C. @ 4.00 mm 汞 Hg
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| 蒸汽压力 Vapor Pressure: | 0.010400 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) |
| 闪点 Flash Point: | 216.00 °F. tcc TCC ( 102.22 °C. )
|
| logp（o / w） logP (o/w): | 2.772（est） 2.772 (est) |
| 溶于 Soluble in: |
| | alcohol | | | 水 water, 略 slightly | | | 水 water, 96.61 mg / l @ 25°c（est） 96.61 mg/L @ 25 °C (est) |
| 不溶于 Insoluble in: |
| | 水 water |
感官特性 Organoleptic Properties:
| 气味类型 Odor Type: nutty |
气味强度 Odor Strength:高 high ,
建议在0.10％或更少的溶液中闻到 recommend smelling in a 0.10 % solution or less |
| green musty nutty |
| 气味描述 Odor Description:at 0.10 % in 二丙烯 dipropylene glycol. 绿的发霉的坚果 green musty nutty |
| 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
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| 危害识别 Hazards identification |
| |
| 物质或混合物的分类 Classification of the substance or mixture |
| 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| 没有找到。 None found. |
| ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
| |
| 象形图 Pictogram | |
| |
| 危险说明 Hazard statement(s) |
| 没有找到。 None found. |
| 防范说明 Precautionary statement(s) |
| 没有找到。 None found. |
| 口服/肠胃外毒性 Oral/Parenteral Toxicity: |
管鼠 gavage-mouse LD50 [性别 sex: M,F] 2673 mg/kg kg
(幼稚的 Babish, 1978a） 1978a)
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| 皮肤毒性 Dermal Toxicity: |
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未定 Not determined
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| 吸入毒性 Inhalation Toxicity: |
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未定 Not determined
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使用安全信息 Safety in Use Information:
| 类别 Category: | flavoring agents |
| 推荐的环己基甲基吡嗪用量不超过 Recommendation for cyclohexyl methyl pyrazine usage levels up to: | | | 不用于香水。 not for fragrance use.
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| |
| 最大化源自调查的每日摄入量（msdi-eu） Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012（微克/ 均/天） 0.012 (μg/capita/day) |
| 最大化源自调查的每日摄入量（msdi-usa） Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.01（微克/ 均/天） 0.01 (μg/capita/day) |
| 结构类 Structure Class: | iii III |
| 采用 Use 等级 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its its 判断 judgments that the 物质 substances are 通常 generally 公认的 recognized as safe (GRAS). |
| The 专家 Expert 面板 Panel also 发表 publishes 分离 separate 广泛 extensive 评论 reviews of scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library |
| 出版编号 publication number: 12 |
| 单击此处查看出版物12 Click here to view publication 12 |
| | 平均 average 通常 usual 百万分之几 ppm | 平均 average 最大 maximum 百万分之几 ppm |
| 焙烤食品 baked goods: | - | 1.00000 |
| 饮料（不含醇） beverages(nonalcoholic): | - | - |
| 醇饮料 beverages(alcoholic): | - | - |
| 早餐麦片 breakfast cereal: | - | - |
| 起司 cheese: | - | - |
| 口香糖 chewing gum: | - | - |
| 调味品/调味品 condiments / relishes: | - | - |
| 糖果烧烤 confectionery froastings: | - | 0.50000 |
| 蛋制品 egg products: | - | - |
| 脂肪/油 fats / oils: | - | - |
| 鱼产品 fish products: | - | - |
| 冷冻乳制品 frozen dairy: | - | - |
| 水果冰 fruit ices: | - | - |
| 明胶/布丁 gelatins / puddings: | - | 0.50000 |
| 砂糖 granulated sugar: | - | - |
| 肉汁 gravies: | - | - |
| 硬糖 hard candy: | - | - |
| 仿乳制品 imitation dairy: | - | 0.20000 |
| 速溶咖啡/茶 instant coffee / tea: | - | - |
| 果酱/果冻 jams / jellies: | - | - |
| 肉制品 meat products: | - | - |
| 奶制品 milk products: | - | - |
| 坚果产品 nut products: | - | 0.50000 |
| 其他谷物 other grains: | - | - |
| 家禽 poultry: | - | - |
| 加工水果 processed fruits: | - | - |
| 加工蔬菜 processed vegetables: | - | - |
| 重构蔬菜 reconstituted vegetables: | - | - |
| 调味料 seasonings / flavors: | - | - |
| 休闲食品 snack foods: | - | 1.00000 |
| 软糖 soft candy: | - | 0.50000 |
| 汤类 soups: | - | - |
| 糖替代品 sugar substitutes: | - | - |
| 甜酱 sweet sauces: | - | - |
安全参考 Safety references:
欧洲食品安全法规（efsa） European Food Safety Athority(efsa):风味使用水平；亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究；发育/ 毒性研究；遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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欧洲食品安全局（efsa EFSA）参考 :
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食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 seasonings / flavors, 与调味品组评估有关的委员会的要求17（fge.17）与食品接触的加工助剂和材料（afc） processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): 吡嗪 Pyrazine 衍生品 derivatives from chemical group 24 (佣金 Commission 规 Regulation (ec EC) No 1565/2000 of 18 July 2000)
视图 View page or 视图 View pdf
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调味组评估50（fge.50） Flavouring Group Evaluation 50 (FGE.50): 请与您的客户服务代表联系。 ticamulsion a-2010在含有20％或更多油的饮料和风味乳液中具有出色的稳定性。 ticamulsion a-2010是冷水可溶的。如果您的过程包括巴氏灭菌或其他高温步骤 Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, 调味料 seasonings / flavors, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC)
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调味组评估17 Flavouring Group Evaluation 17, 版本1（fge.17rev1） Revision 1 (FGE.17Rev1): 化学第24组的吡嗪衍生物-食品添加剂科学小组的意见 Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, 调味料 seasonings / flavors, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC) [1]
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调味品组评价的科学见解17 Scientific Opinion on Flavouring Group Evaluation 17, 版本2（fge.17rev2） Revision 2 (FGE.17Rev2): 吡嗪 Pyrazine 衍生品 derivatives from chemical group 24
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调味品组评价的科学意见50 Scientific Opinion on Flavouring Group Evaluation 50, 版本1（fge.50rev1） Revision 1 (FGE.50Rev1): 考虑 Consideration of pyrazine 衍生品 derivatives 已评估 evaluated by by Jec ECFA (57th 会议 meeting) 结构上 structurally 有关 related to pyrazine 衍生品 derivatives 已评估 evaluated by by efsa EFSA in ge FGE.17Rev2 (2010)
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| Epi系统 EPI System: 视图 View |
| EPA物质注册服务（tsca TSCA） :28217-92-7 |
| EPA ACToR:毒理学资料 Toxicology Data |
| EPA物质注册服务（SRS） :注册表 Registry |
| 实验室化学安全摘要 Laboratory Chemical Safety Summary :16204532 |
| 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data |
| 2-(cyclohexylmethyl)pyrazine |
| chemidplus Chemidplus:0028217927 |
参考资料 References:
| | 2-(cyclohexylmethyl)pyrazine |
| NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
| 加拿大国内分公司。清单 Canada Domestic Sub. List: | 28217-92-7 |
| pubchem（cid） Pubchem (cid): | 16204532 |
| pubchem（sid） Pubchem (sid): | 135264457 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
| 气味 For Odor |
| 巧克力 chocolate |
2,5- dimethyl pyrazine
FL/FR |
| 柑橘类 citrus |
methyl heptenone
FL/FR |
| 泥土的 earthy |
(S)-1- octen-3-ol
FL/FR |
| 脂肪的 fatty |
hexyl pivalate
FR |
| 花的 floral |
戊基 amyl benzoate
FL/FR |
仙客来 cyclamen aldehyde
FL/FR |
| 果味的 fruity |
tetrahydrofurfuryl butyrate
FL/FR |
| green |
2-sec- butyl-3-methoxypyrazine
FL/FR |
| musty |
2- acetyl pyrrole
FL/FR |
3- acetyl-2,5-dimethyl furan
FL/FR |
menthofuran
FL/FR |
| nutty |
2- acetyl-5-methyl furan
FL/FR |
2,3- dimethyl pyrazine
FL/FR |
4,5- dimethyl-2-ethyl-3-thiazoline
FL/FR |
2- ethyl pyrazine
FL/FR |
2- ethyl-4-methyl thiazole
FL/FR |
榛子 filbert pyrazine
FL/FR |
2- methyl pyrazine
FL/FR |
5- methyl quinoxaline
FL/FR |
nutty quinoxaline
FL/FR |
酱油 shoyu pyrazine
FL/FR |
2,3,5,6- tetramethyl pyrazine
FL/FR |
2,3,5- trimethyl pyrazine
FL/FR |
vinyl sulfurol
FL/FR |
| 蜡状的 waxy |
heptyl octanoate
FL/FR |
octyl 2-methyl butyrate
FL/FR |
| 用于调味 For Flavor |
| 找不到适合这些的口味组 No flavor group found for these |
acetyl acetaldehyde dimethyl acetal
FL |
(E)- aconitic acid
FL |
戊基 amyl benzoate
FL/FR |
2,5- diethyl thiazole
FL |
2,5- diethyl-4-methyl thiazole
FL |
(S)-1- octen-3-ol
FL/FR |
3- propyl pyridine
FL |
| cocoa |
| cocoa |
butyraldehyde
FL |
| 咖啡 coffee |
2- ethyl-4-methyl thiazole
FL/FR |
2-iso propyl pyrazine
FL |
| 果味的 fruity |
2,4- hexadien-1-ol
FL |
tetrahydrofurfuryl butyrate
FL/FR |
| green |
仙客来 cyclamen aldehyde
FL/FR |
methyl heptenone
FL/FR |
4- methyl thiazole
FL |
| musty |
2,5- dimethyl pyrazine
FL/FR |
menthofuran
FL/FR |
酱油 shoyu pyrazine
FL/FR |
2,3,5- trimethyl pyrazine
FL/FR |
| nutty |
2- acetyl pyrrole
FL/FR |
3- acetyl-2,5-dimethyl furan
FL/FR |
2- acetyl-5-methyl furan
FL/FR |
2,3- dimethyl pyrazine
FL/FR |
4,5- dimethyl-2-ethyl-3-thiazoline
FL/FR |
2- ethyl pyrazine
FL/FR |
榛子 filbert pyrazine
FL/FR |
2- methyl pyrazine
FL/FR |
5- methyl quinoxaline
FL/FR |
nutty quinoxaline
FL/FR |
nutty thiazole
FL |
花生 peanut oxazole
FL |
2,3,5,6- tetramethyl pyrazine
FL/FR |
vinyl sulfurol
FL/FR |
| 蔬菜 vegetable |
2-sec- butyl-3-methoxypyrazine
FL/FR |
| 蜡状的 waxy |
heptyl octanoate
FL/FR |
octyl 2-methyl butyrate
FL/FR |
潜在用途 Potential Uses:
存在（自然 Occurrence (nature, food, 其他） other): note
| | 自然界中找不到 not found in nature |
同义词 Synonyms:
| ( | cyclohexyl methyl) pyrazine | | 2-( | cyclohexyl methyl) pyrazine | | ( | cyclohexylmethyl)pyrazine | | 2-( | cyclohexylmethyl)pyrazine | | 2- | pyrazine cyclohexyl methyl | | | pyrazine, 2-（环己基甲基）- 2-(cyclohexylmethyl)- | | 2- | pyrazinyl cyclohexyl methyl | | 2- | pyrazinyl methyl cyclohexane | | 2- | pyrazinylcyclohexylmethane | | ( | 吡嗪基甲基 pyrazinylmethyl) cyclohexane | | 2- | 吡嗪基甲基 pyrazinylmethylcyclohexane |
文章 Articles:
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