quinine
cinchonan-9-ol cinchonan-9-ol, 6'-甲氧基- -methoxy-, (8a 8a ,9r)- 9R)-
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类别 Category:cosmetic agents
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笔记 Notes: 一种来自金鸡纳皮的生物碱。它被用作抗疟药 an alkaloid derived from the bark of the cinchona tree. it is used as an antimalarial drug, 消毒剂b部分-用于控制微生物生长的物质。 178.1010消毒解决方案。fda 184部分-被确认为公认安全食品的直接食品b部分-列出被确认为Grassec的特定物质的清单。 184.1061乳酸。 and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. it was used commonly and as a bitter and flavoring agent, 仍可用于治疗杆状杆菌病。奎宁在某些肌肉疾病中也有用 and is still useful for the treatment of babesiosis. quinine is also useful in some muscular disorders, 尤其是夜间腿抽筋和先天性肌强直 especially nocturnal leg cramps and myotonia congenita, 因为它直接作用于肌膜和钠通道。其抗疟作用的机制尚不清楚。用于补品和苦味饮料 because of its direct effects on muscle membrane and sodium channels. the mechanisms of its antimalarial effects are not well understood. Used in tonics and bitter drinks
奎宁是具有解热作用的天然白结晶生物碱 Quinine is a natural white crystalline alkaloid having antipyretic, 抗疟疾 Antimalarial, analgesic, 抗炎特性和苦味。它是奎尼丁的立体异构体 anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, 不像奎宁 unlike quinine, 是一种抗心律不齐的药物。尽管它已经在实验室合成 is an anti-arrhythmic. Though it has been synthesized in the lab, 金鸡纳树的皮是奎宁的唯一已知天然来源。奎宁是第一个有效治疗恶性疟原虫引起的疟疾的方法 the bark of the cinchona tree is the only known natural source of quinine. Quinine was the first effective treatment for malaria caused by Plasmodium falciparum, 出现在17世纪的疗法中。直到1940年代,它一直是首选的抗疟药 appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, 当其他药物代替它。 (维基百科) when other drugs replaced it. (Wikipedia)
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