Name: | 1,3,3-三甲基-2-氧杂双环[2.2.2]辛基-6-乙酸酯 3-trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate |
CAS号 CAS Number: | 72257-53-5 | 3D/INCHI
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ECHA EINECS - REACH 预注册 Pre-Reg: | 276-542-9 |
nikkaji网站 Nikkaji Web: | J299.074A |
XlogP3-AA: | 1.80(est) 1.80 (est) |
分子量 Molecular Weight: | 212.28900000 |
式 Formula: | c12 h20 o3 C12 H20 O3 |
核磁共振预测器 NMR Predictor: | 预测(适用于Chrome或Firefox) Predict (works with chrome or firefox) |
efsa / jecfa评论 EFSA/JECFA Comments: |
注册名称更改为(1r Register name to be changed to (1R, 4s 4S, 6s)-2-氧杂双环[2.2.2] octan-6-ol 6S)-2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-三甲基- 3-trimethyl-, 6乙酸。 6-acetate.
注册名称更改为(1r Register name to be changed to (1R, 4s 4S, 6s)-2-氧杂双环[2.2.2] octan-6-ol 6S)-2-Oxabicyclo[2.2.2]octan-6-ol, 1,3,3-三甲基- 3-trimethyl-, 6乙酸酯(effa 6-acetate (EFFA, 2007b)。 2007b). |
类别 Category:flavoring agents
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
物理性质 Physical Properties:
出现 Appearance: | 无色至浅黄透明液体至固体(est) colorless to pale yellow clear liquid to solid (est) |
化验 Assay: | 95.00至100.00 95.00 to 100.00
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食品化学品法典列表 Food Chemicals Codex Listed: | No |
熔点 Melting Point: | 89.00 °C. @ 760.00 mm 汞 Hg
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沸点 Boiling Point: | 253.00 to 254.00 °C. @ 760.00 mm 汞 Hg (est)
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沸点 Boiling Point: | 299.00 °C. @ 760.00 mm 汞 Hg
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蒸汽压力 Vapor Pressure: | 0.018000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) |
闪点 Flash Point: | > 212.00° tcc(> 100.00°c。) > 212.00 °F. TCC ( > 100.00 °C. )
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logp(o / w) logP (o/w): | 2.261(est) 2.261 (est) |
溶于 Soluble in: |
| alcohol | | 水 water, 227.4 mg / l @ 25°C(est) 227.4 mg/L @ 25 °C (est) |
不溶于 Insoluble in: |
| 水 water |
类似物品 Similar Items:note |
4,7,7-三甲基-8-氧杂双环[2.2.2]辛烷 7-trimethyl-8-oxabicyclo[2.2.2]octane |
感官特性 Organoleptic Properties:
气味类型 Odor Type: herbal |
气味强度 Odor Strength:介质 medium |
minty clean fresh eucalyptus |
气味描述 Odor Description:at 100.00 %. 薄荷干净的新鲜桉树 minty clean fresh eucalyptus |
风味类型 Flavor Type: herbal |
eucalyptus |
口味描述 Taste Description: eucalyptus |
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found). |
化妆品信息 Cosmetic Information:
供应商 Suppliers:
安全信息 Safety Information:
欧洲信息 European information : |
最重要的危害 Most important hazard(s): | xi-刺激性 Xi - Irritant |
r 36/37/38-刺激眼睛 R 36/37/38 - Irritating to eyes, 呼吸系统 respiratory system, and skin 皮. S 02 - 保持 Keep out of the 达到 reach of 孩子们 children. S 26 - In 案件 case of contact with 眼睛 eyes, 冲洗 rinse 立即 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical 忠告 advice. S 36 - 穿 Wear 适当 suitable 保护性 protective 服装 clothing.
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危害识别 Hazards identification |
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物质或混合物的分类 Classification of the substance or mixture |
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
没有找到。 None found. |
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements |
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象形图 Pictogram | |
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危险说明 Hazard statement(s) |
没有找到。 None found. |
防范说明 Precautionary statement(s) |
没有找到。 None found. |
口服/肠胃外毒性 Oral/Parenteral Toxicity: |
未定 Not determined
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皮肤毒性 Dermal Toxicity: |
未定 Not determined
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吸入毒性 Inhalation Toxicity: |
未定 Not determined
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使用安全信息 Safety in Use Information:
类别 Category: | flavoring agents |
推荐2-乙酰氧基-1 Recommendation for 2-acetoxy-1,8-桉树脑使用量最高 8-cineole usage levels up to: | | 不用于香水。 not for fragrance use.
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最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.037(微克/ 均/天) 0.037 (μg/capita/day) |
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3500(微克/ /天) 3500 (μg/person/day) |
关注点 Threshold of Concern: | 540(微克/ /天) 540 (μg/person/day) |
结构类 Structure Class: | ii II |
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根据委员会法规ec EC号的食品类别。 1565/2000(ec , 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the 行业 Industry the "正常 normal" use is 定义的 defined as the 平均 average of 已报告 reported 用法 用法 u智者 sages and "最大 maximum use" is 定义的 defined as the 95th 百分位 percentile of 已报告 reported 用法 用法 u智者 sages (efsa EFSA, 2002i)。 2002i). |
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm |
| 平均 average 用法 u智者 sage mg/kg kg | 最大 maximum 用法 u智者 sage mg/kg kg |
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): | 3.00000 | 15.00000 |
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): | 2.00000 | 10.00000 |
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): | 3.00000 | 15.00000 |
加工水果(04.1) Processed fruit (04.1): | 2.00000 | 10.00000 |
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): | - | - |
糖果(05.0) Confectionery (05.0): | 10.00000 | 50.00000 |
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): | 5.00000 | 25.00000 |
烘焙用具(07.0) Bakery wares (07.0): | 10.00000 | 50.00000 |
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): | 2.00000 | 10.00000 |
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : | 2.00000 | 10.00000 |
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): | - | - |
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): | - | - |
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): | 5.00000 | 25.00000 |
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): | 15.00000 | 75.00000 |
不含醇 Non-alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): | 3.00000 | 15.00000 |
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): | - | - |
即食美味(15.0) Ready-to-eat savouries (15.0): | - | - |
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 |
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
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欧洲食品安全局(efsa EFSA)参考 :
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食品添加剂科学小组的意见 Opinion of the Scientific Panel on food additives, 调味料 flavourings, 与调味品组评估23有关的与食品(afc AFC)接触的加工助剂和材料(fge.23) : 脂族的 Aliphatic, 脂环族和芳族醚,包括来自化学族的苯甲醚衍生物15 alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16 and 26 (佣金 Commission 规 Regulation (ec EC) No 1565/2000 of 18 July 2000 视图 View page or 视图 View pdf
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调味组评估59(fge.59) Flavouring Group Evaluation 59 (FGE.59): 由jecfa(第六十一次会议)评估与脂肪族结构相关的脂肪族和芳香族醚 Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting) structurally related to aliphatic, 由efsa EFSA在fge.23(2006)(委员会法规(ec)1565 / 2000,2000年7月18日)中评估的脂环族和芳族醚,包括苯甲醚衍生物-食品添加剂科学小组的意见 , 调味料 flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in contact with Food (afc AFC) 视图 View page or 视图 View pdf
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调味组评估23 Flavouring Group Evaluation 23, 修订版1(fge.23rev1) Revision 1 (FGE.23Rev1): 脂族的 Aliphatic, 脂环族和芳族醚,包括来自化学族的苯甲醚衍生物15 alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16, 26和30 [1]-食品添加剂科学小组的意见 26 and 30[1] - Opinion of the Scientific Panel on Food Additives, 调味料 flavourings, 处理中 Processing 艾滋病 Aids and 材料 Materials in 联系 Contact with Food 视图 View page or 视图 View pdf
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调味品组评价的科学见解23 Scientific Opinion on Flavouring Group Evaluation 23, 版本2(fge.23rev2) Revision 2 (FGE.23Rev2): 脂族的 Aliphatic, 脂环族和芳族醚,包括来自化学族的苯甲醚衍生物15 alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16, 22, 26 and 30 视图 View page or 视图 View pdf
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调味组评估的科学意见59 Scientific Opinion on Flavouring Group Evaluation 59, 版本1(fge.59rev1) Revision 1 (FGE.59Rev1): jecfa(第六十一次会议和第六十三次会议)评估与脂族结构相关的脂族和芳族醚 Consideration of aliphatic and aromatic ethers evaluated by JECFA (61st meeting and 63rd meeting) structurally related to aliphatic, 脂环族 alicyclic and aromatic ethers 包含 含 including anisole 衍生品 derivatives 已评估 evaluated by by efsa EFSA in ge FGE.23 Rev2 (2010) 视图 View page or 视图 View pdf
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调味品组评价的科学见解23 Scientific Opinion on Flavouring Group Evaluation 23, 版本3(fge.23rev3) Revision 3 (FGE.23Rev3): 脂族的 Aliphatic, 脂环族和芳族醚,包括来自化学族的苯甲醚衍生物15 alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16, 22, 26 and 30 视图 View page or 视图 View pdf
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调味品组评价的科学见解23 Scientific Opinion on Flavouring Group Evaluation 23, 修订版4(fge.23rev4) Revision 4 (FGE.23Rev4): 脂族的 Aliphatic, 脂环族和芳族醚,包括来自化学族的苯甲醚衍生物15 alicyclic and aromatic ethers including anisole derivatives From chemical groups 15, 16, 22, 26 and 30 视图 View page or 视图 View pdf
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Epi系统 EPI System: 视图 View |
EPA物质注册服务(tsca TSCA) :72257-53-5 |
EPA ACToR:毒理学资料 Toxicology Data |
EPA物质注册服务(SRS) :注册表 Registry |
实验室化学安全摘要 Laboratory Chemical Safety Summary :175002 |
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:数据 Data |
1,3,3-三甲基-2-氧杂双环[2.2.2]辛基-6-乙酸酯 3-trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate |
chemidplus Chemidplus:0072257535 |
参考资料 References:
| 1,3,3-三甲基-2-氧杂双环[2.2.2]辛基-6-乙酸酯 3-trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate |
NIST化学网络书籍 NIST Chemistry WebBook: | 搜索INCHI |
pubchem(cid) Pubchem (cid): | 175002 |
pubchem(sid) Pubchem (sid): | 135153937 |
其他资料 Other Information:
潜在搅拌机 Potential Blenders and core 组件 components note
潜在用途 Potential Uses:
存在(自然 Occurrence (nature, food, 其他) other): note
同义词 Synonyms:
2-oxa | bicyclo(2.2.2)octan-6-ol, 1,3,3-三甲基- 3-trimethyl-, acetate | (1R, 4s 4S, 6S)-2-oxa | bicyclo[2.2.2]octan-6-ol, 1,3,3-三甲基- 3-trimethyl-, 6-acetate | 2-oxa | bicyclo[2.2.2]octan-6-ol, 1,3,3-三甲基- 3-trimethyl-, acetate | exo-2- | hydroxycineole acetate | 1,3,3- | trimethyl-2-氧杂双环(2.2.2)辛烷6-醇 2-oxabicyclo(2.2.2)octan-6-ol acetate | 1,3,3- | trimethyl-2-oxabicyclo(2.2.2)octan-6-yl acetate | 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]oct-6-yl acetate | 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]octan-6-ol acetate | 1,3,3- | trimethyl-2-oxabicyclo[2.2.2]octan-6-yl acetate | α alpha,α alpha,6- | trimethyl-7-oxabicycloheptane-3-methanol acetate | (4,7,7- | trimethyl-8-oxabicyclo[2.2.2]octan-5-yl) acetate |
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