1,4-二甲基萘 4-dimethyl naphthalene
naphthalene, 1,4-二甲基 4-dimethyl-

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    d1006 1 D1006 1,4-二甲基萘> 96.0%(gc) 4-Dimethylnaphthalene >96.0%(GC)
Name:1,4-dimethylnaphthalene
CAS号 CAS Number: 571-58-4Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:209-335-9
FDA UNII:BQH3S1I0SO
nikkaji网站 Nikkaji Web:J116.786C
贝尔斯坦数 Beilstein Number:2039842
MDL :mfcd00004037 MFCD00004037
XlogP3:4.40(est) 4.40 (est)
分子量 Molecular Weight:156.22764000
式 Formula:c12 h12 C12 H12
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:information only not used for fragrances or flavors
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
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已发布 PubMed:搜索 Search
NCBI:搜索 Search
 
物理性质 Physical Properties:
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
比重 Specific Gravity:1.01600 @ 25.00 °C.
折光率 Refractive Index:1.61300 @ 20.00 °C.
熔点 Melting Point: 7.60 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 268.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 267.00 to 268.00 °C. @ 760.00 mm 汞 Hg (est)
蒸汽压力 Vapor Pressure:0.013000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est)
闪点 Flash Point:> 230.00° tcc(> 110.00°c。) > 230.00 °F. TCC ( > 110.00 °C. )
logp(o / w) logP (o/w): 4.370
溶于 Soluble in:
 alcohol
 水 water, 25摄氏度(经验值 exp)时为11.4毫克/升
不溶于 Insoluble in:
 水 water
 
感官特性 Organoleptic Properties:
风味类型 Flavor Type: moldy
moldy resinous
口味描述 Taste Description: 发霉的柏油 mouldy tarry
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
1,4-二甲基萘≥95% 4-Dimethylnaphthalene ≥95%
西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich
仅供实验/研究使用。 For experimental / research use only.
1,4-二甲基萘95% 4-Dimethylnaphthalene 95%
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
1,4-二甲基萘> 96.0%(gc) 4-Dimethylnaphthalene >96.0%(GC)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: information only not used for fragrances or flavors
推荐1 Recommendation for 1,4-二甲基萘的使用量高达 4-dimethyl naphthalene usage levels up to:
 不用于香水。 not for fragrance use.
 
推荐1 Recommendation for 1,4-二甲基萘香料的使用水平最高 4-dimethyl naphthalene flavor usage levels up to:
 不用于调味料。 not for flavor use.
 
安全参考 Safety references:
欧洲食品安全局(efsa EFSA)参考 :

活性物质农药风险评估同行评审的结论1 Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene
视图 View page or 视图 View pdf

关于为1设置新mrl的合理意见 Reasoned opinion on the setting of a new MRL for 1,4-dimethylnaphthalene in 土豆 potatoes
视图 View page or 视图 View pdf

与成员国磋商的结果 Outcome of the consultation with Member States, 申请 和efsa对1的农药风险评估 the applicant and EFSA on the pesticide risk assessment for 1,4-dimethylnaphthalene in 光 light of 确认性的 confirmatory data
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
癌症引文 Cancer Citations:搜索 Search
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环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :11304
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:3
1,4-dimethylnaphthalene
chemidplus Chemidplus:0000571584
 
参考资料 References:
 1,4-dimethylnaphthalene
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):11304
pubchem(sid) Pubchem (sid):134976162
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
CHEBI:视图 View
CHEMBL:视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
出口关税代码 Export Tariff Code:2902.90.9000
雾度图 Haz-Map:视图 View
典型的g.c. Typical G.C.
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
没找到 None found
 
潜在用途 Potential Uses:
没找到 None found
 
存在(自然 Occurrence (nature, 餐饮 food, 其他) other):note
 意大利蒿花油@ 0.50% artemisia variabilis flower oil italy @ 0.50%
Data gc GC 搜索 Search Trop Picture
 
同义词 Synonyms:
1,4-dimethyl-naphthalene
1,4-dimethylnaphthalene
1,4-DMN
 naphthalene, 1,4-二甲基 4-dimethyl-
 

文章 Articles:

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已发布 PubMed:5-ht1a受体的激活增强了可乐定在蓝斑中的抑制作用。 Activation of 5-HT1A receptors potentiates the clonidine inhibitory effect in the locus coeruleus.
已发布 PubMed:单线态氧和镍(ii)和硫醇钯(ii)的硫氧化物的生产。 Singlet Oxygen and the Production of Sulfur Oxygenates of Nickel(II) and Palladium(II) Thiolates.
已发布 PubMed:新型非肽内皮素a受体拮抗剂 New non-peptide endothelin-A receptor antagonists: 合成 synthesis, 生物学特性 biological properties, (二甲基氨基)-正吡啶基-的结构与构效关系 and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-,-正嘧啶基- -N-pyrimidinyl-,-n-哒嗪基- -N-pyridazinyl-, 和-n-吡嗪基-1-萘磺酰胺。 and -N-pyrazinyl-1-naphthalenesulfonamides.
已发布 PubMed:2-羟基-n-(3的抗菌作用 Antibacterial effect of 2-hydroxy-N-(3,4-二甲基-5-异恶唑基)-1 4-dimethyl-5-isoxazolyl)- 1, 金黄熊果上的4-萘醌-4-亚胺。 4-naphthoquinone-4-imine on Staphylococcus aureus.
已发布 PubMed:3-羟甲基-3热分解中单线态氧的形成 Formation of singlet oxygen in the thermal decomposition of 3-hydroxymethyl-3,4,4-三甲基-1 4-trimethyl-1,2-二氧杂环丁烷 2-dioxetane, 三重态激发酮的化学来源。 a chemical source of triplet-excited ketones.
已发布 PubMed:内皮素β受体在自发性高血压大鼠肾功能调节中的作用 A role for endothelin ETA receptors in regulation of renal function in spontaneously hypertensive rats.
已发布 PubMed:糖皮质激素受体介导的皮质酮对大鼠背沟核中5-ht1a自身受体功能的抑制。 Glucocorticoid receptor-mediated inhibition by corticosterone of 5-HT1A autoreceptor functioning in the rat dorsal raphe nucleus.
已发布 PubMed:通过微核骨髓试验测定异恶唑基萘醌亚胺的诱变活性。 Mutagenic activity of isoxazolylnaphthoquinoneimines assayed by micronucleus bone marrow test.
已发布 PubMed:β-胡萝卜素在光合藻类中的昼夜节律 Diurnal rhythm of beta-carotene in photosynthetic alga Gonyaulax polyedra.
已发布 PubMed:磺酰胺η-选择性拮抗剂的发现与构效关系。 Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists.
已发布 PubMed:异恶唑基萘醌亚胺对金黄熊果感染小鼠的抗生素活性。 Antibiotic activity of isoxazolylnaphthoquinone imines on mice infected with Staphylococcus aureus.
已发布 PubMed:bms-182874是选择性的 BMS-182874 is a selective, 非肽内皮素eta受体拮抗剂。 nonpeptide endothelin ETA receptor antagonist.
已发布 PubMed:3-溴-2-羟基-n-(3的稳定性测定 Stability determination of 3-bromo-2-hydroxy-N-(3,4-二甲基-5-异恶唑基)-1 4-dimethyl-5-isoxazolyl)- 1,一阶导数分光光度法测定乙醇中的4-萘醌-4-亚胺。 4-naphthoquinon-4-imine in ethanol by first-derivative spectrophotometry.
已发布 PubMed:异恶唑。 8.异恶唑基萘醌衍生物的预制剂研究。 Isoxazoles. 8. Preformulation studies of an isoxazolylnaphthoquinone derivative.
已发布 PubMed:2-羟基-n-(3的合成及一些理化性质 Synthesis and some physiochemical properties of 2-hydroxy-N-(3,4-二甲基-5-异恶唑基)-1 4-dimethyl-5-isoxazolyl)- 1,4-萘醌4-亚胺衍生物。 4-naphthoquinone 4-imine derivatives.
已发布 PubMed:磺酰胺内皮素拮抗剂的发现和口服活性η拮抗剂5-(二甲基氨基)-n-(3的研制 The discovery of sulfonamide endothelin antagonists and the development of the orally active ETA antagonist 5-(dimethylamino)-N-(3,4-二甲基-5-异恶唑基)-1-萘磺酰胺。 4-dimethyl-5-isoxazolyl)-1-naphthalenesulf onamide.
已发布 PubMed:牛心肌肌钙蛋白中cys35-cys84距离的能量转移测量 Energy-transfer measurements of the Cys35-Cys84 distance in bovine cardiac troponin C.
已发布 PubMed:铅对实验性肝癌大鼠体内某些葡萄糖代谢酶的影响 Effect of Plumbagin on some glucose metabolising enzymes studied in rats in experimental hepatoma.
已发布 PubMed:[异恶唑基++萘醌的体外抗菌活性。一世]。 [In vitro antibacterial activity of isoxazolyl++ naphthoquinones. I].
已发布 PubMed:The in 体外 vitro and in 体内 vivo 细胞毒性 细胞毒性 cytotoxicity of 甲萘醌 menadione (维他命 vitamin K3) 反对 against rat 可移植的 transplantable 肝癌 hepatoma 诱发的 induced by by 3'-methyl-4-二甲基 4-dimethyl-氨基 aminoazo苯 benzene.
已发布 PubMed:异恶唑基萘醌对克氏锥虫生长的影响。 Isoxazolylnaphthoquinone effects on the growth of Trypanosoma cruzi.
已发布 PubMed:异恶唑。六 Isoxazoles. VI: 在酸性水溶液中新萘醌胺的化学稳定性方面。 Aspects of the chemical stability of a new naphthoquinone-amine in acidic aqueous solution.
已发布 PubMed:苯的好氧生物降解过程中的底物相互作用。 Substrate interactions during aerobic biodegradation of benzene.
已发布 PubMed:[萘醌-亚胺对纤毛虫和 细单胞菌生产过氧化氢的影响]。 [Effect of naphthoquinone-imines on the production of hydrogen peroxide by Crithidia fasciculata and Leptomonas seymouri].
已发布 PubMed:钯(0)辅助合成的c-glycopyranosyl化合物。 Palladium(0)-assisted synthesis of C-glycopyranosyl compounds.
已发布 PubMed:脱氧核糖核酸回旋酶抑制剂之间的构效关系。 1的合成与生物学评价 Structure-activity relationships among DNA gyrase inhibitors. Synthesis and biological evaluation of 1,2-二氢-4 2-dihydro-4, 4-二甲基-1-氧代-2-萘甲酸作为草酸1-carba生物等排体。 4-dimethyl-1-oxo-2-naphthalenecarboxylic acids as 1-carba bioisosteres of oxolinic acid.
已发布 PubMed:大剂量化疗和自体骨髓移植治疗小细胞肺癌。 High-dose chemotherapy and autologous bone marrow transplantation for the treatment of small cell lung carcinoma.
已发布 PubMed:与rhnull相比,rh阳性和rh阴性血液的 红细胞膜中蛋白质-脂质相互作用的差异 Different protein-lipid interaction in human red blood cell membrane of Rh positive and Rh negative blood compared with Rhnull.
已发布 PubMed:菲和二甲基萘对仓鼠颊囊dmba致癌作用的抑制作用。 Inhibition of DMBA carcinogenesis of hamster buccal pouch by phenanthrene and dimethylnaphthalene.
已发布 PubMed:阿霉素联合治疗成 恶性橙花胶质瘤和脑转移 Treatment of malignant gliomas and brain metastases in adults using a combination of adriamycine, 虚拟机26 VM 26, 和ccnu。 ii型试验的结果。 and CCNU. Results of a type II trial.
已发布 PubMed:阿霉素联合治疗成 恶性橙花胶质瘤和脑转移 Treatment of malignant gliomas and brain metastases in adults using a combination of adriamycine, 虚拟机26 VM 26, 和ccnu。第二阶段试验的结果。 and CCNU. Results of a phase II trail.
已发布 PubMed:[阿霉素治疗成 胶质母细胞瘤和脑转移的试验 [Trial treatment of glioblastomas in adults and cerebral metastais by adriamycin, vm 26和ccnu组合。 ii型试验的结果]。 VM 26 and CCNU combination. Result of a type II trial].
已发布 PubMed:草欧文氏菌酪氨酸酚裂解酶的催化机理 The cardioactive and related properties of N-methyl-N-( -phenylethyl)-1,2,3,4-四氢-6-甲氧基-4 4-tetrahydro-6-methoxy-4,4-二甲基-2-萘胺盐酸盐(2-at-1)。 4-dimethyl-2-naphthylamine hydrochloride (2-AT-1).
已发布 PubMed:微生物碳氢化合物共氧化。一世。诺卡氏菌属土壤分离物对单环和二环碳氢化合物的氧化作用 Microbial hydrocarbon co-oxidation. I. Oxidation of mono- and dicyclic hydrocarbons by soil isolates of the genus Nocardia.
 
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