beta-asarone
顺式2 cis-2,4,5-三甲氧基-1-丙烯基苯 5-trimethoxy-1-propenylbenzene

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  5273-86-9 Beta-细辛98％ 5273-86-9 beta-Asarone 98%
  从细辛中提取的β-细辛。它可能被开发为治疗各种橙花炎性疾病的有希望的候选者。 b-Asarone isolated from the herbs of Asarum sieboldii Miq. It might be developed as a promising candidate to treat various neuroinflammatory diseases. 抗炎作用 anti-inflammatory effects

Name: 1,2,4-三甲氧基-5-[（z）-丙-1-烯基]苯 4-trimethoxy-5-[(Z)-prop-1-enyl]benzene CAS号 CAS Number: 5273-86-9 3D/INCHI echa ECHA einecs Ein INECS - REACH 预注册 Pre-Reg: 226-096-6 FDA UNII: IGA3MH6IUW nikkaji网站 Nikkaji Web: J236.255D 贝尔斯坦数 Beilstein Number: 1910605 MDL : mfcd00009281 MFCD00009281 XlogP3: 3.00（est） 3.00 (est) 分子量 Molecular Weight: 208.25712000 式 Formula: c12 h16 o3 C12 H16 O3 生物活性总结 BioActivity Summary: 清单 listing 核磁共振预测器 NMR Predictor: 预测（适用于Chrome或Firefox） Predict (works with chrome or firefox) 类别 Category:natural substances and extractives   美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent : 谷歌学术 Google Scholar: 搜索 Search 谷歌书 Google Books: 搜索 Search 谷歌学术 Google Scholar: with word "volatile" 搜索 Search 谷歌学术 Google Scholar: with word "flavor" 搜索 Search 谷歌学术 Google Scholar: with word "odor" 搜索 Search 谷歌专利 Google Patents: 搜索 Search 美国专利 US Patents: 搜索 Search 欧盟专利 EU Patents: 搜索 Search pubchem专利 Pubchem Patents: 搜索 Search   物理性质 Physical Properties: 出现 Appearance: 无色至浅黄澄清液体（est） colorless to pale yellow clear liquid (est) 化验 Assay: 95.00至100.00 95.00 to 100.00 食品化学品法典列表 Food Chemicals Codex Listed: No 比重 Specific Gravity: 1.07300 @ 25.00 °C. 折光率 Refractive Index: 1.56100 @ 20.00 °C. 熔点 Melting Point: 62.00 to 63.00 °C. @ 760.00 mm 汞 Hg 沸点 Boiling Point: 264.00 to 267.00 °C. @ 760.00 mm 汞 Hg 蒸汽压力 Vapor Pressure: 0.003000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est) 闪点 Flash Point: > 230.00° tcc（> 110.00°c。） > 230.00 °F. TCC ( > 110.00 °C. ) logp（o / w） logP (o/w): 3.406（est） 3.406 (est) 溶于 Soluble in:   alcohol   水 water, 101.8 mg / l @ 25°C（est） 101.8 mg/L @ 25 °C (est) 不溶于 Insoluble in:   水 water   感官特性 Organoleptic Properties: 来自其他 的气味和/或风味描述（如果找到）。 Odor and/or flavor descriptions from others (if found).   化妆品信息 Cosmetic Information: 没找到 None found   供应商 Suppliers: BOC Sciences 仅供实验/研究使用。 For experimental / research use only. β-细辛醚98％ beta-Asarone 98% 气味 Odor: characteristic 采用 Use: 从细辛中提取的β-细辛。它可能被开发为治疗各种橙花炎性疾病的有希望的候选者。 b-Asarone isolated from the herbs of Asarum sieboldii Miq. It might be developed as a promising candidate to treat various neuroinflammatory diseases. 抗炎作用 anti-inflammatory effects 库姆波 Coompo 仅供实验/研究使用。 For experimental / research use only. β-细辛 beta-asarone -Asarone from 植物 Plants ≥96% 气味 Odor: characteristic 采用 Use: 4-甲基苯基酯对甲苯基水杨酸酯2-羟基苯甲酸4-甲基苯基酯2-羟基苯甲酸4-甲基苯基酯对甲基苯基2-羟基苯甲酸酯对甲基苯基2-羟基苯甲酸酯4-甲基苯基水杨酸酯4-甲基苯基2-羟基苯甲酸酯对甲基苯基2-羟基苯甲酸酯对甲基苯基2-羟基苯甲酸酯4-甲基苯基水杨酸酯（4-甲基苯基）2-羟基苯甲酸酯水杨酸对甲苯基酯水杨酸对甲苯基酯水杨酸 β-Asarone can affect the central nervous system. β-Asarone could attenuate neuronal apoptosis in rat hippocampus and might be a potential candidate for development as a therapeutic agent to manage cognitive impairment associated with conditions such as Alzheimer’s disease. Other authors found β-Asarone could reduce the toxicity of excitatory amino acids and increase the expression of c-fos in the epileptic rat brain. In addition, （3r）-（3r）-（-）-3-甲基环戊烯酮（3r）-3-甲基环戊烯-1-酮（-）-（3r）-3-甲基环戊烯酮（-）-3-甲基环戊烯酮（r）-（ -）-muscone muscone laevo（firmenich） β-Asarone could reduce the injuries of blood vessel endothelium and nerve cells of the cortex and improve the cognitive function of the beta-amyloid hippocampus injection rats. 使用本产品时喝酒或吸烟.p272-不允许带污染的工作服离开工作场所。p273-避免释放到环境中。p280-戴防护手套/穿防护服/戴防护眼罩/戴面罩。p281-使用个 防护装备p301 + p312-如果吞下 Complement β-Asarone is protective against cerebral ischemia in specific way. The administration of β-Asarone could reduce focal cerebral ischemic/reperfusion injury. The Mechanism of β-Asarone in protection of cerebral ischemia was via increasing antioxidants activity related to lesion pathogenesis. 外合成 ExtraSynthese 仅供实验/研究使用。 For experimental / research use only. β-细辛（gc）≥95％ beta-Asarone (GC) ≥95% 西格玛·奥尔德里奇 Sigma-Aldrich: 奥尔德里奇 Aldrich 仅供实验/研究使用。 For experimental / research use only. 顺式2 cis-2,4,5-三甲氧基-1-丙烯苯70％ 5-Trimethoxy-1-propenylbenzene 70% sds sds   安全信息 Safety Information: 首选SDS Preferred SDS: 视图 View 欧洲信息 European information : 最重要的危害 Most important hazard(s): xn-有害。 Xn - Harmful. R 22 - 有害 Harmful if 吞下 swallowed. S 02 - 保持 Keep out of the 达到 reach of 孩子们 children. S 23 - do Do not 呼吸 breath 汽 vapour. S 24/25 - 避免 Avoid contact with skin 皮 and 眼睛 眼睛 eyes. S 36/37/39 - 穿 我们 Wear 适当 suitable 服装 clothing, 手套和眼睛/面部防护。 gloves and eye/face protection.   危害识别 Hazards identification   物质或混合物的分类 Classification of the substance or mixture 根据29 cfr 1910（osha hcs）进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) 没有找到。 None found. ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements   象形图 Pictogram   危险说明 Hazard statement(s) 没有找到。 None found. 防范说明 Precautionary statement(s) 没有找到。 None found. 口服/肠胃外毒性 Oral/Parenteral Toxicity: 未定 Not determined 皮肤毒性 Dermal Toxicity: 未定 Not determined 吸入毒性 Inhalation Toxicity: 未定 Not determined   使用安全信息 Safety in Use Information: 类别 Category: natural substances and extractives 关键影响 IFRA Critical Effect: 致癌性 Carcinogenicity IFRA fragrance 材料 material 规格 浸膏 specification:   奶油状和扩散性。我确实检测到锋利的松针和注入柑橘的前调，这种前调迅速消失了，但除此之外，我完全不能指责这种材料。正如我在2015年5月1日所写的那样，我认为这种干燥的材料让 回想起非常古老的印度檀香木。 cis- and trans-Asarone as such should not be used as fragrance ingredients; essential oils containing cis- or trans-asarone (e.g. calamus oils) should not be used at a level such that the total concentration of cis- and trans-asarone exceeds 0.01% in consumer products.   查看ifra标准 View the IFRA Standard 视图 View IFRA Standards 图书馆 Library for 完成 complete information. 请 Please 评论 review 修正案 Amendment 49 IFRA 文件资料 documentation for 完成 complete information. 成品中的ifra限制极限（％） IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): 1类 Category 1: 产品涂在嘴唇上 Products applied to the lips 见笔记框％ See notebox % 2类 Category 2: 产品应用于腋窝 Products applied to the axillae 见笔记框％ See notebox % 3类 Category 3: 用指尖涂抹在面部/身体上的产品 Products applied to the face/body using fingertips 见笔记框％ See notebox % 4类 Category 4: 与精美香水有关的产品 Products related to fine fragrance 见笔记框％ See notebox %   5类 Category 5: 用手（手掌）涂在脸部和身体上的产品 Products applied to the face and body using the hands (palms), 主要是免修 primarily leave-on 5a类 Category 5A: 用手（手掌）涂抹在身体上的润肤露产品 Body lotion products applied to the body using the hands (palms), 主要是免修 primarily leave-on 见笔记框％ See notebox % 5b类 Category 5B: 用手（手掌）涂在脸上的面部保湿产品 Face moisturizer products applied to the face using the hands (palms), 主要是免修 primarily leave-on 见笔记框％ See notebox % 5c类 Category 5C: 使用手（手掌）涂在手上的护手霜产品 Hand cream products applied to the hands using the hands (palms), 主要是免修 primarily leave-on 见笔记框％ See notebox % 5d类别 Category 5D: 婴儿面霜 Baby Creams, 婴儿油和婴儿滑石粉 baby Oils and baby talc 见笔记框％ See notebox % 6类 Category 6: 口腔和嘴唇暴露的产品 Products with oral and lip exposure 见笔记框％ See notebox %   7类 Category 7: 用手接触头发的产品 Products applied to the hair with some hand contact 7a类 Category 7A: 用手接触头发上的可冲洗产品 Rinse-off products applied to the hair with some hand contact 见笔记框％ See notebox % 7b类 Category 7B: 用手接触头发上的免洗产品 Leave-on products applied to the hair with some hand contact 见笔记框％ See notebox % 8类 Category 8: 肛门 器暴露严重的产品 Products with significant anogenital exposure 见笔记框％ See notebox % 9类 Category 9: 身体和手部暴露的产品 Products with body and hand exposure, 主要冲洗掉 primarily rinse off 见笔记框％ See notebox %   10类 Category 10: 大部分用手接触的家用护理产品 Household care products with mostly hand contact 10a类 Category 10A: 家居护理，不包括气雾剂产品（不包括气雾剂/喷雾产品） Household care excluding aerosol products (excluding aerosol/spray products) 见笔记框％ See notebox % 10b类 Category 10B: 家用喷雾剂 Household aerosol/spray products 见笔记框％ See notebox %   11类 Category 11: 预期与皮肤接触的产品，但从惰性底物到皮肤的香气转移最少 Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate 11a类 Category 11A: 具有预期的皮肤接触特性的产品，但在不暴露于紫外线的情况下，香料从惰性底物到皮肤的转移最少 Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure 见笔记框％ See notebox % 类别11b Category 11B: 预期与皮肤接触的产品，但从惰性底物到皮肤的香料转移最少，可能会暴露于紫外线 Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure 见笔记框％ See notebox % 类别12 Category 12: 非直接接触皮肤的产品 Products not intended for direct skin contact, 转移至皮肤的微不足道或微不足道 minimal or insignificant transfer to skin 见笔记框 See notebox   笔记 Notes: ifra风味要求 IFRA FLAVOR REQUIREMENTS: 由于在第1类和第6类产品中使用时可能会摄入少量的香料成分 Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, 这些材料不仅必须符合ifra标准，而且还必须作为爱奥菲 iofi行为准则（www.爱奥菲 iofi.org）所定义的调味成分被认为是安全的。有关更多详细信息，请参见有关使用ifra标准的指南的第1章。 香水成分限制-便签盒 Fragrance ingredient restriction - Note box 根据已确定的该物质在市售天然来源（如精油）中的最大浓度水平 On the basis of established maximum concentration levels of this substance in commercially available natural sources (like essential oils, 摘录和精华/精粹/精萃） extracts and absolutes), 只要最终消费品中的顺式和反式asaron含量不超过使用这些油和提取物（例如cal蒲油）所产生的这种物质的暴露，就可以接受。 exposure to this substance from the use of these oils and extracts (e.g. Calamus oils) is regarded acceptable as long as the level of cis- and trans-Asarone in the finished consumer product does not exceed 100ppm（0.01％）。 100ppm (0.01 %).   推荐使用β-细辛醚香料的使用水平 Recommendation for beta-asarone flavor usage levels up to:   不用于调味料。 not for flavor use.   安全参考 Safety references: Epi系统 EPI System: 视图 View 化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search 环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search EPA ACToR:毒理学资料 Toxicology Data EPA物质注册服务（SRS） :注册表 Registry 实验室化学安全摘要 Laboratory Chemical Safety Summary :5281758 国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data 德国wgk WGK Germany:3 1,2,4-三甲氧基-5-[（z）-丙-1-烯基]苯 4-trimethoxy-5-[(Z)-prop-1-enyl]benzene chemidplus Chemidplus:0005273869 技术 RTECS:DC3000000 for CAS＃5273-86-9 DC3000000 for cas# 5273-86-9   参考资料 References:   1,2,4-三甲氧基-5-[（z）-丙-1-烯基]苯 4-trimethoxy-5-[(Z)-prop-1-enyl]benzene NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI pubchem（cid） Pubchem (cid): 5281758 pubchem（sid） Pubchem (sid): 134984836 信息基 Pherobase: 视图 View   其他资料 Other Information: （iupac） (IUPAC): 元素的原子量2009 Atomic Weights of the Elements 2009 （iupac） (IUPAC): 元素的原子量2009（pdf） Atomic Weights of the Elements 2009 (pdf) 影片 Videos: 元素周期表 The Periodic Table of Videos RBC : 本网站使用的原子量 Atomic Weights use for this web site （iupac） (IUPAC): 元素周期表 Periodic Table of the Elements CHEBI: 视图 View CHEMBL: 视图 View KEGG (GenomeNet): C10430 hmdb（人类代谢组数据库） HMDB (The Human Metabolome Database): 搜索 Search 出口关税代码 Export Tariff Code: 2909.30.4000 典型的g.c. Typical G.C. vcf在线 VCF-Online: 食品中的挥发性有机化合物 VCF Volatile Compounds in Food 化学蜘蛛 ChemSpider: 视图 View 维基百科 Wikipedia: 视图 View rsc学习化学 RSC Learn Chemistry: 视图 View   潜在搅拌机 Potential Blenders and core components note 没找到 None found   潜在用途 Potential Uses: 没找到 None found   存在（自然 Occurrence (nature, 餐饮 food, 其他） other):note   菖蒲根茎油@ 2.85％ calamus rhizome oil @ 2.85% Data gc GC 搜索 Search Trop Picture   蒲根油@ 1.68％ calamus root oil @ 1.68% Data gc GC 搜索 Search Trop Picture   胡萝卜籽油@ 17.65％ carrot seed oil @ 17.65% Data gc GC 搜索 Search Trop Picture   蜡菊属植物（l。）茂盛的匈牙利油@ 1.50％ helichrysum arenarium (l.) moench oil hungary @ 1.50% Data gc GC 搜索 Search Trop Picture   红树林皮红油古巴@痕量％ mangrove bark red oil cuba @ trace% Data gc GC 搜索 Search Trop Picture   正齿石竹格言越南油@ 5.50％ orthodon dianthera maxim. oil vietnam @ 5.50% Data gc GC 搜索 Search Trop Picture   依兰依兰油CO2提取物@ 0.02％ ylang ylang oil CO2 extract @ 0.02% Data gc GC 搜索 Search Trop Picture   同义词 Synonyms: cis- asarabaccacamphor (Z)- asarone cis- asarone cis-iso asarone cis- asarumcamphor   苯 benzene, 1,2,4-三甲氧基-5-（1-丙烯基）- 4-trimethoxy-5-(1-propenyl)-, (Z)-   苯 benzene, 1,2,4-trimethoxy-5-[(1Z)-1-propen-1-yl]-   苯 benzene, 1,2,4-三甲氧基-5-丙烯基- 4-trimethoxy-5-propenyl-, (Z)- (Z)-5- propenyl-1,2,4-trimethoxy苯 benzene cis-1- propenyl-2,4,5-trimethoxy苯 benzene 顺式2 cis-2,4,5- trimethoxy-1-propenyl苯 benzene (Z)-1,2,4- trimethoxy-5-(1-propenyl)benzene (Z)-1,2,4- trimethoxy-5-(1-propenyl)苯 benzene 1,2,4- trimethoxy-5-[(1Z)-1-propen-1-yl]苯 benzene 1,2,4- trimethoxy-5-[(1Z)-1-propen-1-yl]benzol 1,2,4- trimethoxy-5-[(1Z)-prop-1-en-1-yl]苯 benzene 1,2,4- trimethoxy-5-[(Z)-prop-1-enyl]苯 benzene (Z)-2,4,5- trimethoxypropen-1-ylbenzene 顺式2 cis-2,4,5- trimethoxypropenylbenzene 顺式2 cis-2,4,5- trimethoxypropenyl苯 benzene   文章 Articles: 已发布 PubMed:精油作为植物油中天然防腐剂的功效。 The Efficacy of Essential Oils as Natural Preservatives in Vegetable Oil. 阶段 J-Stage:β-山葵减弱了大鼠海马中β淀粉样蛋白诱导的橙花元凋亡 Beta-Asarone Attenuates Neuronal Apoptosis Induced by Beta Amyloid in Rat Hippocampus 已发布 PubMed: 噪声 noise蒲和α-细辛对噪声暴露大鼠海马依赖型记忆的作用 阶段 J-Stage: β-细辛 β-asarone通过抑制β-淀粉样蛋白海马注射大鼠的橙花元凋亡来改善认知功能 已发布 PubMed:β-山葵素可通过减少衰老加速的易感8小鼠中的岩石表达来防止自噬和突触丧失。 β-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice. 已发布 PubMed:分子 Molecular and chemical 剖析 profiling of '甜 sweet 旗 flag' (菖蒲属 Acorus calamus L.) 种质 germplasm from 印度 India. 已发布 PubMed:选择性离子监测-气相色谱-质谱联用同时测定大鼠血浆中塔氏非洲锥a中的挥发性成分，并在药代动力学研究中应用。 Simultaneous Determination of Volatile Constituents from Acorus tatarinowii Schott in Rat Plasma by Gas Chromatography-Mass Spectrometry with Selective Ion Monitoring and Application in Pharmacokinetic Study. 已发布 PubMed: α-asaron和β-细辛 β-asarone在体外逆转p-糖蛋白介导的多药耐药 , 生物活性的顺式异构体，来自塔哥里氏锥虫。 bioactive cis-trans isomers from Acorus tatarinowii. 已发布 PubMed:菖蒲的传统用途和药理作用概述。 （甜国旗）和其他cor属物种。 An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species. 已发布 PubMed:细辛异养根中鉴定出的成分对 肠道细菌的生长抑制和形态结构效应。 Growth-Inhibiting and morphostructural effects of constituents identified in Asarum heterotropoides root on human intestinal bacteria. 已发布 PubMed:化学成分 Chemical compositions, 植物毒性 phytotoxicity, 的a蒲cal蒲精油的生物活性 and biological activities of Acorus calamus essential oils from Nepal. 已发布 PubMed:β-细辛 Beta-asarone, cor草的主要组成部分 a major component of Acorus tatarinowii Schott, 减轻大鼠大脑中动脉闭塞引起的局灶性脑缺血。 attenuates focal cerebral ischemia induced by middle cerebral artery occlusion in rats. 已发布 PubMed:禾草根茎的根茎及其成分在体内外均抑制过敏反应。 The Rhizomes of Acorus gramineus and the Constituents Inhibit Allergic Response In vitro and In vivo. 已发布 PubMed:β-细辛醚在阿育吠陀索达纳vacha过程中的命运。 Fate of β-asarone in Ayurvedic Sodhana process of Vacha. 已发布 PubMed:[来自塔哥cor香根茎的化学成分]。 [Chemical constituents from rhizomes of Acorus tatarinowii]. 已发布 PubMed:cal蒲根茎精油对脂质体博斯氏嗜bad菌的杀虫成分的鉴定。 Identification of insecticidal constituents of the essential oil of Acorus calamus rhizomes against Liposcelis bostrychophila Badonnel. 已发布 PubMed:合成 Synthesis, 2的抗癌和抗氧化活性 anticancer and antioxidant activities of 2,4,5-三甲氧基查耳酮及其类似物 5-trimethoxy chalcones and analogues from asaronaldehyde: 构效关系。 structure-activity relationship. 已发布 PubMed:消费者和农民在黑胡椒作物保护中使用植物性农药的安全性评估。 Consumer and farmer safety evaluation of application of botanical pesticides in black pepper crop protection. 已发布 PubMed:精油和细辛的抗抑郁作用 Antidepressant-like effects of essential oil and asarone, 一种来自塔哥（菖蒲属 Acorus 塔塔里诺维 tatarinowii）根茎的主要精油成分。 已发布 PubMed: β-细辛 β-asarone通过诱导拉明 lamin b1表达诱导大肠癌细胞衰老。 已发布 PubMed: 气相色谱-质谱分析超临界CO2萃取远志和石chang chang蒲挥发油中的化合物。 已发布 PubMed: 在体外和体内，β-细辛 β-asarone通过线粒体途径通过半胱氨酸蛋白酶的上调诱导诱导结肠结肠癌细胞凋亡。 已发布 PubMed:β-细辛 Beta-asarone, 菖蒲根茎的活跃原理 an active principle of Acorus calamus rhizome, 抑制形态发生 inhibits morphogenesis, 白念珠菌的生物膜形成和麦角甾醇的生物合成。 biofilm formation and ergosterol biosynthesis in Candida albicans. 已发布 PubMed:蚱代谢芒果和茄叶中的挥发性化学成分。 Metabolism by grasshoppers of volatile chemical constituents from Mangifera indica and Solanum paniculatum leaves. 已发布 PubMed:在体外模型和aβpp/ ps1小鼠中，β-asaron通过camkii / creb /​​ bcl-2信号通路抑制橙花元凋亡。 β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice. 已发布 PubMed:α-和β-细辛中的细胞毒性和遗传毒性的比较研究。 Comparative study of the cytotoxicity and genotoxicity of alpha- and Beta-asarone. 已发布 PubMed:脑血管 Cerebrovascular 保护 保护 protection of β-细辛 β-asarone in Alzheimer's 疾病 disease 老鼠 rats: 行为上的 a behavioral, 脑血流量 cerebral blood flow, 生化和基因研究。 biochemical and genic study. 已发布 PubMed:草药产品中的α-和β-细辛。案例研究。 Alpha- and beta-asarone in herbal medicinal products. A case study. 已发布 PubMed:快速hplc-esi-ms / ms方法测定β-细辛 A rapid HPLC-ESI-MS/MS method for determination of β-asarone, 潜在的抗癫痫药 a potential anti-epileptic agent, 口服cal蒲提取物对大鼠的血浆 in plasma after oral administration of Acorus calamus extract to rats. 已发布 PubMed: β-细辛 β-asarone通过减弱beclin-1依赖性自噬保护pc12细胞免受ogd / r诱导的损伤。 已发布 PubMed:β-细辛醚在兔血中的药代动力学 Pharmacokinetics of beta-asarone in rabbit blood, 海hippocampus, 皮层 cortex, 脑干 brain stem, 丘脑和小脑。 thalamus and cerebellum. 已发布 PubMed:gc-ms对家兔β-细辛醚转化和排泄的分析 Analysis of transformation and excretion of β-asarone in rabbits with GC-MS. 已发布 PubMed: β-细辛 β-asarone通过调节jnk减弱大鼠脑缺血再灌注诱导的自噬 , - p-JNK, bcl-2和beclin 1。 Bcl-2 and Beclin 1. 已发布 PubMed:超临界流体萃取和高速逆流色谱法的有效组合，可从塔格里乌斯草中提取和纯化α-细辛醚和β-细辛酮的（e）-和（z）-非对映异构体。 An efficient combination of supercritical fluid extraction and high-speed counter-current chromatography to extract and purify (E)- and (Z)-diastereomers of α-asarone and β-asarone from Acorus tatarinowii Schott. 已发布 PubMed:超临界流体提取₂蒲l。 （阿拉伯文 Supercritical fluid CO₂ extraction of Acorus calamus L. (Arales: 天南星科（天南星科 Araceae）及其对西非亲热（西胞霉 Sitophilus 玉米饼 zeamais motschusky（鞘翅目）的接触毒性 : curculionidae）。 Curculionidae). 已发布 PubMed:一种固相微萃取gc / ms / ms方法，用于快速定量分析食品和饮料中存在法律限制的生物活性调味剂。 A solid-phase microextraction GC/MS/MS method for rapid quantitative analysis of food and beverages for the presence of legally restricted biologically active flavorings. 已发布 PubMed:禾草的酚类成分。 Phenolic constituents of Acorus gramineus. 已发布 PubMed:三种商业上重要的精油对黄曲霉和黑曲霉的萜烯类成分和抗真菌活性。 Terpenoid composition and antifungal activity of three commercially important essential oils against Aspergillus flavus and Aspergillus niger. 已发布 PubMed:佛手子挥发油的杀虫效果和化学成分。 Insecticidal effect and chemical composition of the volatile oil from Bergenia ligulata. 已发布 PubMed:β-asaron抑制气道橙花节前副交感橙花元的突触输入。 Beta-asarone inhibits synaptic inputs to airway preganglionic parasympathetic motoneurons. 已发布 PubMed:巴西红蜂胶 Brazilian red propolis: 未报告的物质 unreported substances, 抗氧化和抗菌活性。 antioxidant and antimicrobial activities. 已发布 PubMed:a蒲的阳性gaba（a）受体调节剂，并通过1d和2d nmr和分子建模对（+）-二氧代草甘醇进行结构分析。 Positive GABA(A) receptor modulators from Acorus calamus and structural analysis of (+)-dioxosarcoguaiacol by 1D and 2D NMR and molecular modeling. 已发布 PubMed:β-细辛胺通过抑制sh-sy5y细胞中凋亡信号调节激酶1的激活来减弱β-淀粉样蛋白诱导的凋亡。 Beta-asarone attenuates beta-amyloid-induced apoptosis through the inhibition of the activation of apoptosis signal-regulating kinase 1 in SH-SY5Y cells. 已发布 PubMed:中草药汤的质量评估 Quality assessment of a formulated Chinese herbal decoction, 开新山 Kaixinsan, 快速分离液相色谱-质谱联用 by using rapid resolution liquid chromatography coupled with mass spectrometry: 不同历史公式的化学评估。 A chemical evaluation of different historical formulae. 已发布 PubMed:厚朴酚和厚朴酚的橙花保护作用 Neuroprotective effect of honokiol and magnolol, 木兰的化合物 compounds from Magnolia officinalis, 对β-淀粉样蛋白诱导的pc12细胞毒性的影响。 on beta-amyloid-induced toxicity in PC12 cells. 已发布 PubMed:甲氧基化查耳酮作为抗疟药的构效关系的再研究 Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: 2的综合与评价 synthesis and evaluation of 2,4,5-三甲氧基取代的图案作为先导候选物，衍生自大量可用的天然β-细辛。 5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone. 已发布 PubMed:on草化学成分研究 [Study on the chemical constituents of Humulus scandens]. 已发布 PubMed:β-细辛醚减弱了大鼠海马中β-淀粉样蛋白诱导的橙花元凋亡。 Beta-asarone attenuates neuronal apoptosis induced by Beta amyloid in rat hippocampus. 已发布 PubMed:β-细辛醚通过抑制β-淀粉样蛋白海马注射大鼠的橙花元凋亡来改善认知功能 Beta-asarone improves cognitive function by suppressing neuronal apoptosis in the beta-amyloid hippocampus injection rats. 已发布 PubMed:t蒿乙醇提取物油醚馏分的化学成分 [Chemical constituents from petroleum ether fraction of ethanol extract of Acorus tatarinowii]. 已发布 PubMed:车uch灵脂溶性成分的研究 [Research on liposoluble ingredients of Quchiling]. 已发布 PubMed:β-花生四烯酮可通过jnk信号传导和bcl-2家族蛋白的调节，保护pc12细胞中β-淀粉样蛋白诱导的橙花毒性。 Beta-asarone protection against beta-amyloid-induced neurotoxicity in PC12 cells via JNK signaling and modulation of Bcl-2 family proteins. 已发布 PubMed:天然苯基丙烷及其半合成衍生物对烟草粘虫斜纹夜蛾（fab。）（鳞毛蕨）的杀幼虫和结构活性研究 Larvicidal and structure-activity studies of natural phenylpropanoids and their semisynthetic derivatives against the tobacco armyworm Spodoptera litura (Fab.) (Lepidoptera: 夜蛾科）。 Noctuidae). 已发布 PubMed:点地梅ar蒲油中毒相关的细辛的生物分析研究。 Bioanalytical investigation of asarone in connection with Acorus calamus oil intoxications. 已发布 PubMed:煎剂可减少非洲草根中β-细辛醚的含量。 Reduction of beta-asarone in acori rhizoma by decoction. 已发布 PubMed:菖蒲不同野生种群根茎精油的组成变化和止痛作用。及其主要组成部分 Compositional variations and anthelmentic activity of essential oils from rhizomes of different wild populations of Acorus calamus L. and its major component, β-细辛。 beta-Asarone. 已发布 PubMed:补充紫外线b引起a蒲的精油组成和总酚的变化。 （甜标记）。 Supplemental ultraviolet-B induced changes in essential oil composition and total phenolics of Acorus calamus L. (sweet flag). 已发布 PubMed:高效液相色谱法同时测定 血浆中的罗格列酮和吉非贝齐。 A high performance liquid chromatography method for simultaneous determination of rosiglitazone and gemfibrozil in human plasma. 已发布 PubMed:菖蒲精油成分对三种植物病原真菌的熏蒸抗真菌活性。 Fumigant antifungal activity of essential oil components from Acorus gramineus against three phytopathogenic fungi. 已发布 PubMed:在充分稀释的按摩混合物中呕吐和痉挛。可能有助于牙痛 Volatiles from leaves and rhizomes of Fragrant Acorus spp. (Acoraceae). 已发布 PubMed:香菜中植物精油及其成分的杀 活性 Nematicidal activity of plant essential oils and components from coriander (Coriandrum sativum), 东方甜（东方枫香） Oriental sweetgum (Liquidambar orientalis), 和缬草（缬草 valeriana Wallichii wallichii）精油对付松木 （bursaphelenchus 木糖 xylophilus）。 已发布 PubMed:β-细辛醚对青霉素诱导的癫痫大鼠皮层fos和gad65表达的影响 [Effects of beta-asarone on expression of FOS and GAD65 in cortex of epileptic rat induced by penicillin]. 已发布 PubMed: β-细辛醚对点燃性癫痫大鼠脑中c-fos c-fos表达的影响 已发布 PubMed:离线超临界CO2萃取-气相色谱-质谱联用系统研究非洲广co香中富含β-细辛的挥发油 Systematic study of beta-asarone-rich volatile oil from Acori graminei rhizoma by off-line supercritical CO2 extraction-gas chromatography-mass spectrometry. 已发布 PubMed:推荐用于洋甘菊花/薰衣草花/ 厚朴叶/迷迭香厚朴叶/丹参厚朴叶提取物的使用量最高可达推荐用于乳酸菌/两性马提尼水果/薰衣草花/蔷薇蔷薇果实/迷迭香叶/鼠尾草叶/百里香叶提取物发酵滤液的风味​​水平最高可达 Rapid determination of volatile constituents in safflower by microwave distillation and simultaneous solid-phase microextraction coupled with gas chromatography-mass spectrometry. 已发布 PubMed: 绿藻ultra pertusa的化学成分研究 已发布 PubMed:β-细辛醚对谷氨酸诱导的大鼠皮质橙花元损伤的保护作用 [Protective effects of beta-asarone on cultured rat cortical neurons damage induced by glutamate]. 已发布 PubMed:[β-细辛醚对pc12细胞和培养的大鼠皮质橙花元的形态和细胞活力的影响]。 [Effects of beta-asarone on morphology and cell viability in PC12 cells and cultured rat cortical neurons]. 已发布 PubMed:菖蒲的一部分l。不含β-细辛醚的提取物可增强3t3-111细胞的脂肪细胞分化。 A fraction of Acorus calamus L. extract devoid of beta-asarone enhances adipocyte differentiation in 3T3-L1 cells. 已发布 PubMed:a蒲精油及其主要成分的体外乙酰胆碱酯酶抑制活性。 In vitro acetylcholinesterase inhibitory activity of the essential oil from Acorus calamus and its main constituents. 已发布 PubMed:Anno片对慢性癫痫大鼠皮层s100b和npy的影响 [Effects of annao tablet on S100B and NPY of cortex in chronic epilepsy rats]. 已发布 PubMed: 顶空固相微萃取后气相色谱/质谱的快速发展，可快速测定血浆中的asarones Asarones。 已发布 PubMed:高效薄层色谱法定量测定cal蒲中的β-asaron。 Quantitative determination of beta-asarone in calamus by high-performance thin-layer chromatography. 已发布 PubMed:没药油（膝盖）的精油和超临界二氧化碳萃取物的化学成分。和a蒲l蒲属。 Chemical composition of the essential oil and supercritical CO2 extract of Commiphora myrrha (Nees) Engl. and of Acorus calamus L. 已发布 PubMed:当归根挥发物提取物的抗氧化活性 Antioxidative activity of volatile extracts isolated from Angelica tenuissimae roots, 薄荷叶 peppermint leaves, 松针 pine needles, 和甜国旗叶。 and sweet flag leaves. 已发布 PubMed:鉴定一个ecori限制性酶切位点，以快速，准确地测定无β-细辛醚的a蒲菖蒲细胞型。 Identification of an EcoRI restriction site for a rapid and precise determination of beta-asarone-free Acorus calamus cytotypes. 已发布 PubMed:胶束电动毛细管色谱法快速评估cal蒲的β-asaron含量。 Rapid assessment of beta-asarone content of Acorus calamus by micellar electrokinetic capillary chromatography. 已发布 PubMed:β-细辛醚在大鼠体内的药代动力学 [Pharmacokinetics of beta-asarone in rats]. 已发布 PubMed:t香挥发油根茎中gc-ms指纹图谱的研究 [Study on GC-MS fingerprint analysis in rhizome of volatile oil of Acorus tatarinowii]. 已发布 PubMed:超声辅助将有毒的β-细辛转化为无毒的生物活性苯基丙烷 Ultrasound-assisted conversion of toxic beta-asarone into nontoxic bioactive phenylpropanoid: 异二十烷酮 isoacoramone, 边缘缘 marginatum和塔哥a骨的代谢产物。 已发布 PubMed:禾草根茎的β-细辛醚的抗真菌活性。 Antifungal activity of beta-asarone from rhizomes of Acorus gramineus. 已发布 PubMed:[β-asaron对小鼠脑中基因表达的影响]。 [Effects of beta-asaron on gene expression in mouse brain]. 已发布 PubMed:草酸 及其有效成分可保护pc-12细胞免受淀粉样β肽的毒性作用。 Rhizoma acori graminei and its active principles protect PC-12 cells from the toxic effect of amyloid-beta peptide. 已发布 PubMed:保护细胞对大鼠皮层橙花元的毒杀作用 Protection of cultured rat cortical neurons from excitotoxicity by asarone, 禾草根茎中的主要精油成分。 a major essential oil component in the rhizomes of Acorus gramineus. 已发布 PubMed:一个温和而便捷的程序，将有毒的β-山葵转化为稀有的苯基丙烷 A mild and convenient procedure for the conversion of toxic beta-asarone into rare phenylpropanoids: 2,4,5-三甲氧基肉桂醛和γ-细辛。 5-trimethoxycinnamaldehyde and gamma-asarone. 已发布 PubMed:[关于永生（蜡菊属植物arenchium（l。）moench。）花序的精油成分的新数据]。 [New data on composition of esssential oil from inflorescence of everlasting (Helichrysum arenarium(L.) Moench.)]. 已发布 PubMed:一步将有毒的β-细辛从cal蒲转化为1-（2 One step conversion of toxic beta-asarone from Acorus calamus into 1-(2,4,5-三甲氧基苯基）-1 5-trimethoxyphenyl)-1,在 子中存在2-二羟基丙烷和天冬酰胺。 2-dihydroxypropane and asaronaldehyde occurring in Piper clusii. 已发布 PubMed: 淋巴细胞和具有代谢能力的 肝癌细胞系hep-g2中的微核形成 Micronucleus formation in human lymphocytes and in the metabolically competent human hepatoma cell line Hep-G2: 15种天然物质的合成结果。 results with 15 naturally occurring substances. 已发布 PubMed:对某些药用南美植物埃及伊蚊幼虫的杀虫活性。 Insecticidal activity against Aedes aegypti larvae of some medicinal South American plants. 已发布 PubMed:樟子松根皮中的抗真菌和杀幼虫化合物。 Antifungal and larvicidal compounds from the root bark of Cordia alliodora. 已发布 PubMed: sos在大肠杆菌中诱导选定的天然存在的物质（sos 色度测试 chromotest）。 已发布 PubMed:精油成分不同的cal蒲菖蒲化学型的dna分析。 DNA profiling of Acorus calamus chemotypes differing in essential oil composition. 已发布 PubMed:gc-ms和tlc技术用于测定Asarone异构体的比较。 Comparison of GC-MS and TLC techniques for asarone isomers determination. 已发布 PubMed:弓形虫第二阶段幼虫中细辛及其相关苯基丙烷的迁移抑制和杀 活性 Mobility inhibition and nematocidal activity of asarone and related phenylpropanoids on second-stage larvae of Toxocara canis. 已发布 PubMed:烯基苯α-和β-山葵酮的遗传毒性 Genotoxicity of the alkenylbenzenes alpha- and beta-asarone, 如通过uds测定法在培养的大鼠肝细胞中测定的肉豆蔻霉素和依立美霉素。 myristicin and elimicin as determined by the UDS assay in cultured rat hepatocytes. 已发布 PubMed:烯丙基苯和丙烯基苯的结构-遗传毒性关系 Structure-genotoxicity relationships of allylbenzenes and propenylbenzenes: 量子化学研究。 a quantum chemical study. 已发布 PubMed:β-细辛醚对小鼠和大鼠的抗凝作用。 The anticoagulant effect of beta-asarone in the mouse and the rat. 已发布 PubMed:来自aco蒲属的朝霞油 Asarones fromAcorus calamus L. Oil : 它们对鳞茎皮虫的摄食行为和饮食利用的影响。 Their effect on feeding behavior and dietary utilization inPeridroma saucia. 已发布 PubMed:for细辛的抗过敏成分 [Antianaphylactic components of Asarum forbsii Maxin]. 已发布 PubMed:β-细辛的测定 Determination of beta-asarone, safrole, 高效液相色谱法测定醇饮料中的异黄酮和茴香脑 isosafrole and anethole in alcoholic drinks by high-performance liquid chromatography. 已发布 PubMed:syner-gx＆trade;是通过植物提取和生物技术获得的瓜尔胶和黄原胶的混合物。这种100％天然增稠剂可稳定配方，为配方带来柔滑感。 Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice. 已发布 PubMed: spasmolytische 威贡 wirkung des 异花生四烯酸 isoasaronfreien kalmus 1。 已发布 PubMed:定量分析 Quantitative analysis of alpha, β-beta-thujone, 长叶薄荷酮、胡薄荷酮 pulegone, safrole, 通过选择离子监测可以监测醇饮料中的香豆素和β-细辛。 coumarin and beta-asarone in alcoholic beverages by selected-ion monitoring. 已发布 PubMed:鼠 歐洲海濱草对β-细辛和商业cal蒲药物的致突变性测试。 Mutagenicity testing of beta-asarone and commercial calamus drugs with Salmonella typhimurium. 已发布 PubMed:[用超临界气体萃取热不稳定化合物。]。 [Extraction of thermolabile compounds with supercritical gases.]. 已发布 PubMed:[由无β-细辛的cal蒲组成的精油。]。 [Composition of the essential oil from beta-Asarone free calamus.]. 已发布 PubMed:[对商业cal蒲药物的分类]。 [To the classification of commercial Calamus drugs]. 已发布 PubMed:[将质谱仪用作通过气-液色谱法分析醇饮料中的特定检测器]。 [Use of the mass spectrometer as a specific detector in the analysis of alcoholic beverages by gas-liquid chromatography]. 已发布 PubMed:气液色谱法测定葡萄酒中的β-细辛 Gas-liquid chromatographic determination of beta-asarone in wine: 合作学习。 collaborative study. 已发布 PubMed:分光光度法测定甜和干燥苦艾酒中的β-细辛醚 Spectrofluorometric determination of beta-asarone in sweet and dry vermouths. 已发布 PubMed:气相色谱法测定葡萄酒和调味料中的β-细辛醚 Gas-liquid chromatographic determination of beta-asarone in wines and flavors. 已发布 PubMed:[薄层 Thin-layer 皮肤造影 cromatographic and 密度计 densitometric 评价 evaluation of beta-asarone in 酒鬼 alcoholic 调味的 flavored 饮料 beverages (author's 翻译 transl)]. 已发布 PubMed:细辛和β-细辛醚对条件反应的影响 Effects of asarone and beta-asarone on conditioned responses, 战斗行为和抽搐。 fighting behaviour and convulsions. 已发布 PubMed:对a蒲的研究。 vi。细辛和β-细辛对心血管系统和平滑肌的药理作用。 Studies on Acorus calamus. VI. Pharmacological actions of asarone and beta-asarone on cardiovascular system and smooth muscles. 已发布 PubMed:对a蒲的研究。 v。细辛和β-细辛对中枢橙花系统的药理作用。 Studies on Acorus calamus. V. Pharmacological actions of asarone and beta-asarone on central nervous system. 已发布 PubMed:细辛和β-细辛的药效学作用。 Pharmacodynamical effects of asarone and beta-asarone.

笔记 Notes: 没找到 None found