环丙烷羧酸(2-异丙基-5-甲基环己基)酰胺 cyclopropane carboxylic acid (2-isopropyl-5-methyl cyclohexyl) amide
环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide

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CAS号 CAS Number: 958660-02-1Picture of molecule3D/INCHI
FDA UNII:4G2NYA84QJ
XlogP3-AA:3.50(est) 3.50 (est)
分子量 Molecular Weight:223.35945000
式 Formula:c14 h25 n o C14 H25 N O
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
CAS号 CAS Number: 958660-04-3Picture of molecule3D/INCHI
FDA UNII:1N849XD4QD
XlogP3-AA:3.50(est) 3.50 (est)
分子量 Molecular Weight:223.35945000
式 Formula:c14 h25 n o C14 H25 N O
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
efsa / jecfa评论 EFSA/JECFA Comments:
两桶分配958660-02-1(1s Two CASrn assigned 958660-02-1 (1S,2s 2S,5r)和958660-04-3(1r 5R) and 958660-04-3 (1R,2R,5s)。最小测定是异构体的总和 5S). Min assay is sum of isomers: 两个主要的异构体和四个其他的立体异构体。指定混合物的组成。 Two main isomers and four other stereoisomers. Composition of mixture to be specified.
类别 Category:flavor enhancers
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
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调香师和调味师 Perfumer and Flavorist:搜索 Search
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jecfa食品调味料 JECFA Food Flavoring:2006 环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide

2006 环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide
dg sante食品调味料 DG SANTE Food Flavourings:16.115环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 16.115 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide
fema号 FEMA Number:4558 环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide
4558 环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide
自由贸易区 FDA:不再提供这七种合成调味剂的使用 No longer provide for the use of these seven synthetic flavoring substances
fda mainterm(satf) FDA Mainterm (SATF):977188-03-6 ; CYCLOPROPANECARBOXYLIC ACID (2-ISOPROPYL-5-METHYL-CYCLOHEXYL)酰胺 -AMIDE
 
物理性质 Physical Properties:
出现 Appearance:白粉末(est) white powder (est)
化验 Assay: 98.00至100.00 98.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 166.00 °C. @ 760.00 mm 汞 Hg
溶于 Soluble in:
 水 water, 25°C(est)时为10.14 mg / l 10.14 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
气味类型 Odor Type: savory
气味强度 Odor Strength:高 high ,
建议在0.10%或更少的溶液中闻到 recommend smelling in a 0.10 % solution or less
savory brothy umami
气味描述 Odor Description:at 0.10 % in propylene glycol. 轻度 mild 咸肉汤鲜味 savory brothy umami
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
Parchem Parchem
环丙烷羧酸(2-异丙基-5-甲基环己基)酰胺 cyclopropane carboxylic acid (2-isopropyl-5-methyl cyclohexyl) amide
化学资源协会 Chemical sources Association Inc
需要这个物品来调味/食用吗? Need This Item for Flavor/Food?: 您 You can contact the 化学资源协会 Chemical sources Association Inc
 
安全信息 Safety Information:
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
灌胃鼠 gavage-rat LD50 [性别 sex: F] > 2000 mg/kg kg
(瓦斯 Vaeth, 2007)

皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category: flavor enhancers
推荐的环丙烷羧酸(2-异丙基-5-甲基环己基)酰胺的使用量最高为 Recommendation for cyclopropane carboxylic acid (2-isopropyl-5-methyl cyclohexyl) amide usage levels up to:
 不用于香水。 not for fragrance use.
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 3.00(微克/ 均/天) 3.00 (μg/capita/day)
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): 960(微克/ /天) 960 (μg/person/day)
关注点 Threshold of Concern:90(微克/ /天) 90 (μg/person/day)
结构类 Structure Class: iii III
采用 Use 等级 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its its 判断 judgments that the 物质 substances are 通常 generally 公认的 recognized as safe (GRAS).
The 专家 Expert 面板 Panel also 发表 publishes 分离 separate 广泛 extensive 评论 reviews of scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library
出版编号 publication number: 24.更新出版物号 24. Update in publication number(s): 26
点击这里查看出版物24 Click here to view publication 24
 平均 average 通常 usual 百万分之几 ppm平均 average 最大 maximum 百万分之几 ppm
焙烤食品 baked goods: --
饮料(不含醇) beverages(nonalcoholic): 0.200001.70000
醇饮料 beverages(alcoholic): --
早餐麦片 breakfast cereal: --
起司 cheese: 2.000006.00000
口香糖 chewing gum: 10.0000050.00000
调味品/调味品 condiments / relishes: 4.0000010.00000
糖果烧烤 confectionery froastings: 1.0000020.00000
蛋制品 egg products: 4.0000010.00000
脂肪/油 fats / oils: 2.000008.00000
鱼产品 fish products: 2.000008.00000
冷冻乳制品 frozen dairy: --
水果冰 fruit ices: --
明胶/布丁 gelatins / puddings: --
砂糖 granulated sugar: --
肉汁 gravies: 4.0000010.00000
硬糖 hard candy: --
仿乳制品 imitation dairy: --
速溶咖啡/茶 instant coffee / tea: --
果酱/果冻 jams / jellies: --
肉制品 meat products: 2.000008.00000
奶制品 milk products: --
坚果产品 nut products: --
其他谷物 other grains: --
家禽 poultry: 2.000008.00000
加工水果 processed fruits: --
加工蔬菜 processed vegetables: 2.000008.00000
重构蔬菜 reconstituted vegetables: --
调味料 seasonings / flavors: 10.0000020.00000
休闲食品 snack foods: 8.0000020.00000
软糖 soft candy: --
汤类 soups: 4.0000010.00000
糖替代品 sugar substitutes: --
甜酱 sweet sauces: --
 
根据委员会法规EC号的食品类别。 1565/2000(ec Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the Industry the "正常 normal" use is 定义的 defined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 defined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (efsa EFSA, 2002i)。 2002i).
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm
 平均 average 用法 usage mg/kg kg最大 maximum 用法 usage mg/kg kg
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): 2.000006.00000
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): 2.000008.00000
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): --
加工水果(04.1) Processed fruit (04.1): --
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): 2.000008.00000
糖果(05.0) Confectionery (05.0): --
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): --
烘焙用具(07.0) Bakery wares (07.0): --
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): 2.000008.00000
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : 2.000008.00000
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): 4.0000010.00000
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): --
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): 10.0000020.00000
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): --
不含醇 Non-酒鬼 alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): 0.200001.70000
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): --
即食美味(15.0) Ready-to-eat savouries (15.0): 8.0000020.00000
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

关于调味剂组评估的科学意见300(fge.300) Scientific Opinion on Flavouring Group Evaluation 300 (FGE.300): one One 脂环族 cyclo-aliphatic amide from chemical group 33
视图 View page or 视图 View pdf

关于调味品组评估的科学意见300 Scientific Opinion on Flavouring Group Evaluation 300, 版本1(fge.300rev1) Revision 1 (FGE.300Rev1): one One 脂环族 cyclo-aliphatic amide from chemical group 33
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :58004815
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:2
n-[(1秒 N-[(1S,2s 2S,5r)-5-甲基-2-丙-2-基环己基]环丙烷甲酰胺 5R)-5-methyl-2-propan-2-ylcyclohexyl]cyclopropanecarboxamide
chemidplus Chemidplus:0958660021
n-[(1r N-[(1R,2R,5s)-5-甲基-2-丙-2-基环己基]环丙烷甲酰胺 5S)-5-methyl-2-propan-2-ylcyclohexyl]cyclopropanecarboxamide
chemidplus Chemidplus:0958660043
 
参考资料 References:
 n-[(1秒 N-[(1S,2s 2S,5r)-5-甲基-2-丙-2-基环己基]环丙烷甲酰胺 5R)-5-methyl-2-propan-2-ylcyclohexyl]cyclopropanecarboxamide
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):58004815
pubchem(sid) Pubchem (sid):163643017
 n-[(1r N-[(1R,2R,5s)-5-甲基-2-丙-2-基环己基]环丙烷甲酰胺 5S)-5-methyl-2-propan-2-ylcyclohexyl]cyclopropanecarboxamide
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):59847877
pubchem(sid) Pubchem (sid):163643018
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):搜索 Search
o FAO:环丙烷羧酸(2-异丙基-5-甲基-环己基)-酰胺 Cyclopropanecarboxylic acid (2-isopropyl-5-methyl-cyclohexyl)-amide
 
潜在搅拌机 Potential Blenders and 核心组件 core components note
气味 For Odor
多肉的 meaty
多肉的 meaty dithiane
FL/FR
用于调味 For Flavor
多肉的 meaty
多肉的 meaty dithiane
FL/FR
bis(2-
methyl-3-furyl) disulfide
FL
 
潜在用途 Potential Uses:
没找到 None found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 自然界中找不到 not found in nature
 
同义词 Synonyms:
 环丙烷羧酸(1r cyclopropanecarboxylic acid (1R,2R,5S)-(2-isopropyl-5-ethylcyclohexyl)-amide
 cyclopropanecarboxylic acid (1S,2s 2S,5R)-(2-isopropyl-5-ethylcyclohexyl)-amide
 环丙烷羧酸(2-异丙基-5-甲基环己基)-酰胺 cyclopropanecarboxylic acid (2-isopropyl-5-methylcyclohexyl)-amide
n-[(1秒 N-[(1S,2s 2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]cyclopropanecarboxamide
N-(2-isopropyl-5-methylcyclohexyl)cyclopropanecarboxamide
 

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