theobromine
3,7-二甲基嘌呤-2 7-dimethylpurine-2,6-dione

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    83-67-0可可碱> 98% 83-67-0 Theobromine >98%
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    产品 Product(s):
    20-23550可可碱 20-23550 THEOBROMINE
    20-23560可可碱天然20% 20-23560 THEOBROMINE NATURAL 20%
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    w0226可可碱 W0226 Theobromine
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    t0178可可碱> 98.0%(hplc)(t) T0178 Theobromine >98.0%(HPLC)(T)
Name:3,7-二甲基嘌呤-2 7-dimethylpurine-2,6-dione
CAS号 CAS Number: 83-67-0Picture of molecule3D/INCHI
echa ECHA einecs EINECS - REACH 预注册 Pre-Reg:201-494-2
FDA UNII:OBD445WZ5P
nikkaji网站 Nikkaji Web:J3.874A
贝尔斯坦数 Beilstein Number:0016464
MDL :mfcd00022830 MFCD00022830
XlogP3:-0.80(est) -0.80 (est)
分子量 Molecular Weight:180.16716000
式 Formula:c7 h8 n4 o2 C7 H8 N4 O2
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:flavoring agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
 FDA/DG SANTE Petitions, 评论 Reviews, 告示 Notices:
GRN 340 Theobromine 视图 View - notice pdf格式 PDF
Flavis号码 FLAVIS Number:16.032(旧) 16.032 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:16.032可可碱 16.032 theobromine
fema号 FEMA Number:3591 theobromine
自由贸易区 FDA:不再提供这七种合成调味剂的使用 No longer provide for the use of these seven synthetic flavoring substances
fda mainterm(satf) FDA Mainterm (SATF):83-67-0 ; THEOBROMINE
 
物理性质 Physical Properties:
出现 Appearance:白粉末(est) white powder (est)
化验 Assay: 98.00至100.00 98.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
熔点 Melting Point: 345.00 to 350.00 °C. @ 760.00 mm 汞 Hg
闪点 Flash Point: 32.00 °F. tcc TCC ( 0.00 °C. ) (est)
logp(o / w) logP (o/w): -0.780
保质期 Shelf Life: 如果正确存储,则为24.00个月或更长时间。 24.00 month(s) or longer if stored properly.
存储 Storage:存放在阴凉处 store in cool, 干燥处,密封容器中 dry place in tightly sealed containers, 免受热和光照。 protected from heat and light.
溶于 Soluble in:
 alcohol
 水 water, 1.248e+004 mg/L @ 25 &deg °C (est)
 水 water, 330毫克/升@ 25摄氏度(经验值 exp)
不溶于 Insoluble in:
 水 water
 
感官特性 Organoleptic Properties:
风味类型 Flavor Type: bitter
bitter
口味描述 Taste Description: bitter
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: 掩蔽剂 masking agents
皮肤调理 skin conditioning
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
可可碱> 98% Theobromine >98%
Penta International
可可碱20% THEOBROMINE NATURAL 20%
Penta International
THEOBROMINE
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
Theobromine
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
可可碱≥99.0% Theobromine ≥99.0%, 固体 solid
Synerzine
Theobromine
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
可可碱> 98.0%(hplc)(t) Theobromine >98.0%(HPLC)(T)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
欧洲信息 European information :
最重要的危害 Most important hazard(s):
xn-有害。 Xn - Harmful.
R 22 - 有害 Harmful if 吞下 swallowed.
S 02 - 保持 Keep out of the 达到 reach of 孩子们 children.
S 20/21 - 什么时候 When 使用 using do not eat, 喝 drink or 抽烟 smoke.
S 24/25 - 避免 Avoid contact with skin and 眼睛 eyes.
S 26 - In 案件 case of contact with 眼睛 eyes, 冲洗 rinse 立即 即时 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical 忠告 advice.
S 36 - 穿 我们 Wear 适当 suitable 保护性 protective 服装 clothing.
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
口鼠 口服 oral-rat LD50 1265 mg/kg kg
Gigiena 特鲁达 Truda i Professional'奈 nye Zabolevaniya Zabolevaniya. 劳工 Labor 卫生 Hygiene and 职业的 Occupational 疾病 Diseases. 卷 Vol. 26(3), pg。 59 Pg. 59, 1982.

老鼠 口服 oral-mouse LD50 837 mg/kg kg
Gigiena 特鲁达 Truda i Professional'奈 nye Zabolevaniya Zabolevaniya. 劳工 Labor 卫生 Hygiene and 职业的 Occupational 疾病 Diseases. 卷 Vol. 26(3), pg。 59 Pg. 59, 1982.

口头的 口服 oral- 的 human ldlo LDLo 26 mg/kg kg
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 86, pg。 113 Pg. 113, 1946.

腹腔内小鼠 intraperitoneal-mouse LD50 552 mg/kg kg
BEHAVIORAL: 抽搐 CONVULSIONS OR 影响 EFFECT ON 发作 SEIZURE THRESHOLD
Acta 药房 Pharmaceutica 卷 Vol. 46, pg。 93 Pg. 93, 1996.

口猫 口服 oral-cat LD50 200 mg/kg kg
"Prehled 恶作剧 Prumyslove 毒物学 Toxikologie; 有机酮 Organicke 懒汉 Latky," 马尔霍尔德 Marhold, j. J., 布拉格 Prague, 捷克斯洛伐克 Czechoslovakia, 香橙 Avicenum, 1986卷-- 1986Vol. -, pg. 1372 Pg. 1372, 1986.

口头狗 口服 oral-dog LD50 300 mg/kg kg
Toxicology and 已应用 Applied 药理 Pharmacology. 卷 Vol. 53, pg。 481 Pg. 481, 1980.

口头的 口服 oral- 的 human tdlo TDLo 26 mg/kg kg
BEHAVIORAL: 运动活动的变化(特异性测定) CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) 胃肠道 GASTROINTESTINAL: 恶心 NAUSEA OR VOMITING
Journal of 药理 Pharmacology and 实验性的 Experimental 疗法 Therapeutics. 卷 Vol. 86, pg。 113 Pg. 113, 1946.

皮肤毒性 Dermal Toxicity:
皮下兔子 皮下 sub皮肤的 cutaneous-rabbit ldlo LDLo 1000 mg/kg kg
"Abdernalden's 手铐 Handbuch der 生物化学 Biologischen Arbeitsmethoden Arbeitsmethoden." 卷 Vol. 4, pg. 1289 Pg. 1289, 1935.

皮下老鼠 皮下 sub皮肤的 cutaneous-mouse LD50 530 mg/kg kg
Arzneimittel-Forschung. 药品 Drug 研究 Research. 卷 Vol. 6, pg。 601 Pg. 601, 1956.

吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
flavoring agents
关于可可碱使用量的建议 Recommendation for theobromine usage levels up to:
 不用于香水。 not for fragrance use.
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 30.00(微克/ 均/天) 30.00 (μg/capita/day)
结构类 Structure Class: iii III
采用 Use 等级 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its 判断 judgments that the 物质 substances are 通常 一般 generally 公认的 recognized as safe (GRAS).
The 专家 Expert 面板 Panel 也 also 发表 publishes 分离 separate 广泛 extensive 评论 评论 reviews of 科学的 scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library
出版编号 publication number: 11
单击此处查看出版物11 Click here to view publication 11
 平均 average 通常 usual 百万分之几 ppm平均 average 最大 maximum 百万分之几 ppm
焙烤食品 baked goods: -1050.00000
饮料(不含醇) beverages(nonalcoholic): --
醇饮料 beverages(alcoholic): --
早餐麦片 breakfast cereal: --
起司 cheese: --
口香糖 chewing gum: --
调味品/调味品 condiments / relishes: --
糖果烧烤 confectionery froastings: -4020.00000
蛋制品 egg products: --
脂肪/油 fats / oils: --
鱼产品 fish products: --
冷冻乳制品 frozen dairy: --
水果冰 fruit ices: --
明胶/布丁 gelatins / puddings: -795.00000
砂糖 granulated sugar: --
肉汁 gravies: --
硬糖 hard candy: --
仿乳制品 imitation dairy: --
速溶咖啡/茶 instant coffee / tea: --
果酱/果冻 jams / jellies: --
肉制品 meat products: --
奶制品 milk products: -990.00000
坚果产品 nut products: --
其他谷物 other grains: --
家禽 poultry: --
加工水果 processed fruits: --
加工蔬菜 processed vegetables: --
重构蔬菜 reconstituted vegetables: --
调味料 seasonings / flavors: --
休闲食品 snack foods: --
软糖 soft candy: -4020.00000
汤类 soups: --
糖替代品 sugar substitutes: --
甜酱 sweet sauces: -3300.00000
 
根据委员会法规EC号的食品类别。 1565/2000(ec Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the Industry the "正常 normal" use is 定义的 defined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 defined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (e (EFSA, 2002i)。 2002i).
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm
 平均 average 用法 usage mg/kg kg最大 maximum 用法 usage mg/kg kg
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): 20.0000070.00000
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): --
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): --
加工水果(04.1) Processed fruit (04.1): --
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): --
糖果(05.0) Confectionery (05.0): --
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): --
烘焙用具(07.0) Bakery wares (07.0): --
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): --
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : --
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): --
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): --
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): --
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): 75.00000100.00000
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): --
即食美味(15.0) Ready-to-eat savouries (15.0): --
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

调味组评估29(fge29)[1]-优先列表中的物质 Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: 化学组31中的乙烯基苯-食品添加剂专家组的科学意见 Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, 调味料 seasonings / flavors, 处理中 Processing 艾滋病 Aids and 材料 Materials in 联系 Contact with Food (afc AFC)
视图 View page or 视图 View pdf

调味组评估49 Flavouring Group Evaluation 49, (fge.49)[1] (FGE.49)[1]: 黄嘌呤 Xanthin 生物碱 生物碱 alkaloids from the 优先 Priority list from chemical group 30
视图 View page or 视图 View pdf

调味品组评价的科学见解49 Scientific Opinion on Flavouring Group Evaluation 49, 版本1(fge.49rev1) Revision 1 (FGE.49Rev1): 黄嘌呤 xanthine 生物碱 生物碱 alkaloids from the 优先 priority list
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
Clinicaltrials.gov ClinicalTrials.gov:search
nlm NLM有害物质数据库 :搜索 Search
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
辅助引文 AIDS Citations:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
epa遗传毒理学 EPA GENetic TOXicology:搜索 Search
环境诱变信息中央 Env. Mutagen Info. Center:搜索 Search
橙花发育和 毒性 NLM Developmental and Reproductive Toxicity:搜索 Search
EPA物质注册服务(tsca TSCA) :83-67-0
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :5429
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:1
3,7-二甲基嘌呤-2 7-dimethylpurine-2,6-dione
chemidplus Chemidplus:0000083670
epa / noaa客串 EPA/NOAA CAMEO:有害物质 hazardous materials
技术 technology:xh2275000 for CAS#83-67-0 XH2275000 for cas# 83-67-0
 
参考资料 References:
 3,7-二甲基嘌呤-2 7-dimethylpurine-2,6-dione
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:83-67-0
pubchem(cid) Pubchem (cid):5429
pubchem(sid) Pubchem (sid):134971694
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
嗯bbd UM BBD:搜索 Search
KEGG (GenomeNet):C07480
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB02825
食物 FooDB:FDB000455
出口关税代码 Export Tariff Code:2934.99.4400
fda食品添加剂状况清单 FDA Listing of Food Additive Status:视图 View
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
配方/制剂 Formulations/Preparations:
•复盐或可可碱钙和水杨酸钙的混合物。含有不少于44%的可可碱。白 •double salt or mixture of calcium theobromine and calcium salicylate. contains no less than 44% theobromine. white, 无定形粉末。略带盐味。部分溶于水。水溶液对酚酞是碱性的。水杨酸钙 amorphous powder. slightly saline taste. partly sol in water. aqueous solutions are alkaline to phenolphthalein. calcium salicyclate 可可碱和乙酸钠的等摩尔混合物 •equimolar mixture of sodium theobromine and sodium acetate, 包含1 h2o。可可碱59.6% containing 1 h2o. theobromine 59.6%, 无水乙酸钠27.1%。白 anhydrous sodium acetate 27.1%. white, 无味或几乎无味 odorless or almost odorless, 吸湿粉。从空气中吸收二氧化碳,变得不完全溶解。易溶于水 hygroscopic powder. absorbs co2 from the air becoming incompletely soluble. very soluble in water, 微溶于冷醇;溶液是强碱性的。醋酸钠 sparingly soluble in cold alcohol; the solutions are strongly alkaline. sodium acetate 可可碱钠和水杨酸钠的等摩尔混合物 •equimolar mixture of sodium theobromine and sodium salicylate, 包含1h2o。可可碱47.3% containing 1h2o. theobromine 47.3%, 水杨酸钠为42.1%。白 sodium salicylate 42.1%. white, 无味的,几乎无味的 odorless of almost odorless, 吸湿粉。从空气中吸收二氧化碳,变得不完全溶解。溶于1份水;微溶于乙醇 hygroscopic powder. absorbs co2 from the air becoming incompletely soluble. soluble in 1 part water; slightly soluble in alcohol: 溶液是强碱性的。 ph值约10.水杨酸钠 the solutions are strongly alkaline. ph about 10. sodium salicylate
 
潜在搅拌机 Potential Blenders and core 组件 components note
气味 For Odor
找不到这些气味组 No odor group found for these
龙胆属 gentiana lu茶 tea 根 root 提取 额外 extract
FL/FR
李 prunus 血清 serotina 皮 酒吧 bark 提取 额外 extract
FL/FR
醛 aldehydic
醛 aldehydic
citronellyl oxyacetaldehyde
FL/FR
tridecanal
FL/FR
香醋 balsamic
秘鲁 peru 香脂 balsamoil
FL/FR
秘鲁 peru 香脂 balsam resinoid
FL/FR
萜品基 特平 terpinyl isovalerate
FL/FR
焦糖色 caramellic
胡芦巴 fenugreek oleoresin
FL/FR
蜡菊 immortelle ab溶胶 solute
FL/FR
巧克力 chocolate
cocoa hexenal
FL/FR
cocoa oleoresin
FL/FR
citrus
2-
heptanol
FL/FR
(+)-
nootkatone
FL/FR
bitter
橙子 o范围 range 皮 peeloil brazil
FL/FR
cocoa
theobroma cacao 提取 额外 extract
FL/FR
咖啡 coffee
coffea arabica seed 提取 额外 extract
FL/FR
烤 roasted arabica
咖啡豆 coffee beanoil
FL/FR
脂肪的 fatty
(e (E,Z,Z)-2,4,7-
tridecatrienal
FL/FR
花的 floral
(Z)-
jasmone
FL/FR
nerol
FL/FR
萜品基 特平 terpinyl valerate
FL/FR
干草 hay
烟草 tobacco leaf ab溶胶 solute
FL/FR
herbal
levisticum officinale 根 root 提取 额外 extract
FL/FR
香 incense
frankincense gum papyrifera
FL/FR
麝香 musk
dextro,laevo-
muscone
FL/FR
粉状的 powdery
dibenzyl ketone
FL/FR
茶 tea
camellia oleifera leaf 提取 额外 extract
FL/FR
用于调味 For Flavor
香醋 balsamic
秘鲁 peru 香脂 balsamoil
FL/FR
秘鲁 peru 香脂 balsam resinoid
FL/FR
bitter
2-
acetyl-5-methyl pyrrole
FL
amarogentin
FL
cocoa 吡嗪 pyrazines base (混合物 mixture of 吡嗪 pyrazines)
FL
dibenzyl ketone
FL/FR
3,4-
dihydroxybenzaldehyde
FL
frankincense gum papyrifera
FL/FR
glyceryl tribut butyrate
FL
methyl ethoxypyrazine
FL
1,3-
octane diol
FL
paullinia cupana seed 提取 额外 extract
FL
特平 terpin 无水的 anhydrous
FL
萜品基 特平 terpinyl isovalerate
FL/FR
(e (E,Z,Z)-2,4,7-
tridecatrienal
FL/FR
棕色 brown
胡芦巴 fenugreek oleoresin
FL/FR
胡桃 juglans nigra 船体 hulls 提取 额外 extract
FL
胡桃 juglans nigra 壳 shell 提取 额外 extract
FL
巧克力 chocolate
bitter
巧克力 chocolate flavor
FL
苦乐参半 bitter甜 sweet
巧克力 chocolate flavor
FL
cocoa oleoresin
FL/FR
citrus
citronellyl oxyacetaldehyde
FL/FR
bitter
柠檬 lemon flavor
FL
nerol
FL/FR
(+)-
nootkatone
FL/FR
bitter
橙子 o范围 range flavor
FL
cocoa
cocoa distillates
FL
cocoa hexenal
FL/FR
theobroma cacao 提取 额外 extract
FL/FR
咖啡 coffee
coffea arabica seed 提取 额外 extract
FL/FR
冷却 cooling
(2s (2S,5R)-n- -N-[4-(2-
amino-2-oxoethyl)phenyl]-5-methyl-2-(propan-2-yl)cyclohexanecarboxamide
FL
果味的 fruity
2-
heptanol
FL/FR
bitter
橙子 o范围 range 皮 peeloil brazil
FL/FR
李 prunus 血清 serotina 皮 酒吧 bark 提取 额外 extract
FL/FR
萜品基 特平 terpinyl valerate
FL/FR
草木 grassy
烟草 tobacco leaf ab溶胶 solute
FL/FR
绿 green
龙胆属 gentiana lu茶 tea 根 root 提取 额外 extract
FL/FR
蜡菊 immortelle ab溶胶 solute
FL/FR
麝香 musk
dextro,laevo-
muscone
FL/FR
坚果 nutty
花生 pea坚果 nut oxazole
FL
烤 roasted
acer spicatum 皮 酒吧 bark 提取 额外 extract
FL
烤 roasted arabica
咖啡豆 coffee beanoil
FL/FR
辣的 spicy
levisticum officinale 根 root 提取 额外 extract
FL/FR
含硫的 sulfurous
2-
methyl thiophene
FL
茶 tea
camellia oleifera leaf 提取 额外 extract
FL/FR
蜡状的 waxy
tridecanal
FL/FR
木本 woody
ginseng distillates
FL
(Z)-
jasmone
FL/FR
 
潜在用途 Potential Uses:
没找到 None Found
 
存在(自然 Occurrence (nature, food, 其他) other):note
 可可豆 cacao bean
搜索 Search Trop Picture
 可可叶柄 cacao petiole
搜索 Search Trop Picture
 可可种 cacao testa
搜索 Search Trop Picture
 可可豆 cacao bean
搜索 Search Trop Picture
 可可叶柄 cacao petiole
搜索 Search Trop Picture
 咖啡豆 coffee bean
搜索 Search Trop Picture
 咖啡叶 coffee leaf
搜索 Search Trop Picture
 瓜拉那 guarana
搜索 Search Trop Picture
 可乐果 kola nut
搜索 Search Trop Picture
 柠檬 lemon
搜索 Search Trop Picture
 柚 pomelo
搜索 Search Trop Picture
 茶花药 tea anther
搜索 Search Trop Picture
 茶花 tea flower
搜索 Search Trop Picture
 茶叶 tea leaf
搜索 Search Trop Picture
 茶果皮 tea pericarp
搜索 Search Trop Picture
 茶籽 tea seed
搜索 Search Trop Picture
 茶籽皮 tea seed coat
搜索 Search Trop Picture
 茶梗 tea stem
搜索 Search Trop Picture
 
同义词 Synonyms:
3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione
2,6-dihydroxy-3,7-dimethyl purine
2,6-dihydroxy-3,7-dimethyl-purine
2,6-dihydroxy-3,7-dimethylpurine
3,7-dimethyl 黄嘌呤 xanthine
3,7-dimethyl-1,3,7-三氢嘌呤-2 7-trihydropurine-2,6-dione
3,7-dimethyl-2,3,6,7-四氢-1h-嘌呤-2 7-tetrahydro-1H-purine-2,6-dione
3,7-dimethyl-3,7-二氢-1h-嘌呤-2 7-dihydro-1H-purine-2,6-dione
3,7-dimethyl-黄嘌呤 xanthine
3,7-dimethylpurine-2,6-dione
3,7-di甲基黄嘌呤 methyl黄嘌呤 xanthine
 尿素 diuretin
 diurobromine
1H-purine-2, 3,7-dihydro-3,7-dimethyl-
1H-purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-
1H-purine-2,6-dione,3,7-dihydro-3,7- dimethyl-
 脑溴蛋白 teobromin
 theobromin
 theobromine 自然 natural
 茶糖 theosalvose
 雌激素 theostene
 至今 thesodate
 黄嘌呤 xanthine, 3,7-dimethyl-
 

文章 Articles:

美国专利 US Patents:4,006,261-用可可碱和环状二肽的混合物调味 261 - Flavoring with mixtures of theobromine and cyclic dipeptides
已发布 PubMed:可可碱增强大鼠中可可多酚的吸收。 Theobromine enhances absorption of cacao polyphenol in rats.
已发布 PubMed:三种茶的化学成分不同可能解释了它们对自发性高血压大鼠急性血压的不同作用。 Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive rats.
已发布 PubMed:采摘期绿茶中主要成分的定量分析及其抗氧化活性 Quantitative analysis of major constituents in green tea with different plucking periods and their antioxidant activity.
已发布 PubMed:生物碱与运动员的免疫功能 Alkaloids and athlete immune function: caffeine, theophylline, 姜醇 gingerol, 麻黄碱 ephedrine, 和他们的同类。 and their congeners.
已发布 PubMed:鉴定和确定八种常见草药减肥补品中掺假药的合成药物。 Identification and determination of synthetic pharmaceuticals as adulterants in eight common herbal weight loss supplements.
已发布 PubMed:可可茶化学成分之间的相互作用 Interactions among chemical components of Cocoa tea (Camellia ptilophylla Chang), 一种天然的低咖啡因茶种。 a naturally low caffeine-containing tea species.
已发布 PubMed:可可植物化学物质 Cocoa phytochemicals: 关于健康的分子机制的最新进展。 recent advances in molecular mechanisms on health.
已发布 PubMed:眼袋手术后患者的饮食可能会影响眼袋炎症。 Diet of patients after pouch surgery may affect pouch inflammation.
已发布 PubMed:可可和巧克力中甲基黄嘌呤的健康益处。 Health benefits of methylxanthines in cacao and chocolate.
已发布 PubMed:同时测定咖啡因 Simultaneous determination of caffeine, 动力学分光光度法测定食品样品中的茶碱和可可碱。 theophylline and theobromine in food samples by a kinetic spectrophotometric method.
已发布 PubMed:液相色谱-串联质谱法同时定量大鼠血浆中咖啡因及其三种主要代谢产物。 Simultaneous quantification of caffeine and its three primary metabolites in rat plasma by liquid chromatography-tandem mass spectrometry.
已发布 PubMed:fuzhuanins a和b Fuzhuanins A and B: 福砖砖茶中flavan-3-ols的b环裂变内酯。 the B-ring fission lactones of flavan-3-ols from Fuzhuan brick-tea.
已发布 PubMed:[关于调味剂和食品制造领域中的调味剂和调味剂规定]。 [About flavouring substances and flavouring preparations regulation in the field of manufacturing of flavourings and foodstuffs].
已发布 PubMed:巴拉圭冬青提取的生物活性化合物的浓度希尔。通过纳滤。 Concentration of biologically active compounds extracted from Ilex paraguariensis St. Hil. by nanofiltration.
已发布 PubMed:可可和 类健康。 Cocoa and human health.
已发布 PubMed:瓜拉那粉多糖 Guarana powder polysaccharides: 果胶级分的抗氧化活性的鉴定和评估。 characterisation and evaluation of the antioxidant activity of a pectic fraction.
已发布 PubMed:高压超快速液相色谱法测定草药靛灰叶/野靛草中甲基黄嘌呤的方法开发与验证。 Development and validation of a rapid ultra high pressure liquid chromatographic method for the determination of methylxanthines in herbal infusions.
已发布 PubMed:新型内含子微RNA参与参与小食咖啡中咖啡因生物合成的正甲基转移酶基因的交叉调控。 Involvement of a novel intronic microRNA in cross regulation of N-methyltransferase genes involved in caffeine biosynthesis in Coffea canephora.
已发布 PubMed:瓦斯拉拉可可树的多样性 Diversity of cacao trees in Waslala, 尼加拉瓜 Nicaragua: 基因型谱之间的关联 associations between genotype spectra, 产品质量和产量潜力。 product quality and yield potential.
已发布 PubMed:饮食营养与短期和长期睡眠时间有关。来自全国代表性样本的数据。 Dietary nutrients associated with short and long sleep duration. Data from a nationally representative sample.
已发布 PubMed:瓜拉那提取物(paullinia cupana)对暴露于硝普钠的成纤维细胞nih-3t3细胞的保护作用。 The protective effects of guaraná extract (Paullinia cupana) on fibroblast NIH-3T3 cells exposed to sodium nitroprusside.
已发布 PubMed:可可简历种子发育过程中酚类化合物和嘌呤生物碱分子谱trinitario。 Profiles of phenolic compounds and purine alkaloids during the development of seeds of Theobroma cacao cv. Trinitario.
已发布 PubMed:通过巧克力和咖啡中的苦味化合物来改变 参的风味。 Modification of ginseng flavors by bitter compounds found in chocolate and coffee.
已发布 PubMed:糖类型对可可黄烷醇生物利用度的影响。 Influence of sugar type on the bioavailability of cocoa flavanols.
已发布 PubMed:色谱低压流动注射系统的开发 Development of a chromatographic low pressure flow injection system: 应用于咖啡中甲基黄嘌呤的分析。 application to the analysis of methylxanthines in coffee.
已发布 PubMed:在高效液相色谱中执行温度编程的一般策略-进一步提高分段温度梯度的保留时间预测的准确性。 A general strategy for performing temperature-programming in high performance liquid chromatography--further improvements in the accuracy of retention time predictions of segmented temperature gradients.
已发布 PubMed:食物链中的生物碱-自然发生和可能的不良影响。 Alkaloids in the human food chain--natural occurrence and possible adverse effects.
已发布 PubMed:普茶化学成分的Comparison of the chemical constituents of aged pu-erh tea, 普茶 ripened pu-erh tea, 和其他使用hplc-dad-esi-msn的茶。 and other teas using HPLC-DAD-ESI-MSn.
已发布 PubMed:减肥药制剂引起的多形红斑样喷发会引起皮肤不良药物反应。 Erythema multiforme-like eruption from a slimming drug preparation cutaneous adverse drug reaction.
已发布 PubMed:市售黑巧克力中的黄烷醇和甲基黄嘌呤 Flavanols and methylxanthines in commercially available dark chocolate: 与脱脂可可固体的相关性研究。 a study of the correlation with nonfat cocoa solids.
已发布 PubMed:快速测定原花青素的方法 Rapid methods to determine procyanidins, 花青素 anthocyanins, 液相色谱-串联质谱法测定大鼠组织中的可可碱和咖啡因。 theobromine and caffeine in rat tissues by liquid chromatography-tandem mass spectrometry.
已发布 PubMed:青少年和青少年近视眼中的维生素D血液水平。 Blood levels of vitamin D in teens and young adults with myopia.
已发布 PubMed:caffeine, 己酮可可碱和茶碱与iq型杂环芳香胺形成堆积复合物。 pentoxifylline and theophylline form stacking complexes with IQ-type heterocyclic aromatic amines.
已发布 PubMed:可可碱和可可的药理作用。 Theobromine and the pharmacology of cocoa.
已发布 PubMed: 类饮食中的天然化合物及其结合诱变剂的能力可防止dna诱变剂的嵌入。 Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation.
已发布 PubMed:能量饮品 Energy drinks: 审查运动员的使用和安全性。 a review of use and safety for athletes.
已发布 PubMed:酚酸和甲基黄嘌呤的组成及对羟基苯甲酸甲酯残基的抗氧化性能。 Phenolic acids and methylxanthines composition and antioxidant properties of mate (Ilex paraguariensis) residue.
已发布 PubMed:使用新型快速梯度窄孔整体柱,通过高效液相色谱快速测定实际样品中的甲基黄嘌呤。 Rapid determination of methylxanthines in real samples by high-performance liquid chromatography using the new FastGradient narrow-bore monolithic column.
已发布 PubMed:食用伴侣饮料时提取的甲基黄嘌呤和酚类物质含量。 Methylxanthines and phenolics content extracted during the consumption of mate (Ilex paraguariensis St. Hil) beverages.
已发布 PubMed:天然可可作为饮食介导的抗疟疾预防。 Natural cocoa as diet-mediated antimalarial prophylaxis.
已发布 PubMed:茶油叶中主要多酚和多酚成分的鉴定 Identification of a major polyphenol and polyphenolic composition in leaves of Camellia irrawadiensis.
已发布 PubMed:改进的液相色谱串联质谱法快速测定角豆粉的酚类化合物和生物碱。 Rapid determination of phenolic compounds and alkaloids of carob flour by improved liquid chromatography tandem mass spectrometry.
已发布 PubMed:西洛他唑 Cilostazol: 新药。间歇性lau行 new drug. Intermittent claudication: 疗效太差 too little efficacy, 太多的风险。 too many risks.
已发布 PubMed:工业上加工的富含多酚的可可粉的抗高血压作用,可保存可可豆的原始类黄酮。 Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans.
已发布 PubMed:自我管理的半定量食物频率问卷用于估计日常日常脂肪的有效性和可重复性 Validity and reproducibility of a self-administered semi-quantitative food-frequency questionnaire for estimating usual daily fat, 纤维 fibre, alcohol, 比利时绝经后妇女的咖啡因和可可碱摄入量。 caffeine and theobromine intakes among Belgian post-menopausal women.
已发布 PubMed:间歇性lau行的药物治疗。 Pharmacologic therapy for intermittent claudication.
已发布 PubMed:可乐果提取物作为食品成分的安全性评估。 Safety assessment of kola nut extract as a food ingredient.
已发布 PubMed:己酮可可碱 Pentoxifylline in ALS: 在皮肤病学领域具有广泛应用的药物。 a drug with wide spectrum applications in dermatology.
已发布 PubMed:抗tnf疗法可减少在吗啡酮诱导的心脏恶病质中大鼠骨骼肌的浪费。 Anti-TNF treatment reduces rat skeletal muscle wasting in monocrotaline-induced cardiac cachexia.
已发布 PubMed:伴侣中的甲基黄嘌呤生物碱和酚类化合物的定量分析及其对鸡胚血管形成的影响。 Quantitation of methylxanthinic alkaloids and phenolic compounds in mate (Ilex paraguariensis) and their effects on blood vessel formation in chick embryos.
已发布 PubMed:可可酚提取物保护 hepg2细胞抗氧化应激。 Protection of human HepG2 cells against oxidative stress by cocoa phenolic extract.
已发布 PubMed:长期服用咖啡因和应激对大鼠进食行为的影响。 Effects of chronic administration of caffeine and stress on feeding behavior of rats.
已发布 PubMed:高效液相色谱法同时测定咖啡因 Simultaneous HPLC determination of caffeine, theobromine, 和食物中的茶碱 and theophylline in food, 饮料 beverages, 和草药产品。 and herbal products.
已发布 PubMed:食品中咖啡因及相关化合物的测定 Determination of caffeine and associated compounds in food, 饮料 beverages, 天然产物 natural products, 药品 pharmaceuticals, 和化妆品采用胶束电动毛细管色谱法。 and cosmetics by micellar electrokinetic capillary chromatography.
已发布 PubMed:马兜铃酸短期毒性 Short-term toxicity of aristolochic acid, 大鼠马兜铃酸-i和马兜铃酸-ii。 aristolochic acid-I and aristolochic acid-II in rats.
已发布 PubMed:多酚与巧克力脱脂可可固形物含量之间的预测关系。 Predictive relationship between polyphenol and nonfat cocoa solids content of chocolate.
已发布 PubMed:最早的可可饮料的化学和考古证据。 Chemical and archaeological evidence for the earliest cacao beverages.
已发布 PubMed:小鼠体内脂多糖和曲伐沙星共同暴露会导致特异性样肝损伤,浸膏取决于肿瘤坏死因子-α。 Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.
已发布 PubMed:蛋白ept来源对产气荚膜梭状芽孢杆菌孢子形成的影响。 Influence of peptone source on sporulation of Clostridium perfringens type A.
已发布 PubMed:在环境影响下生长的不同巴拉圭冬虫后代中嘌呤生物碱选择性液体二氧化碳提取。 Selective liquid CO2 extraction of purine alkaloids in different Ilex paraguariensis progenies grown under environmental influences.
已发布 PubMed:儿茶素的同时分析 Simultaneous analysis of catechins, 没食子酸 gallic acid, 严格的 strictinin, 儿茶酚作为内标,用于绿茶中的嘌呤生物碱。 and purine alkaloids in green tea by using catechol as an internal standard.
已发布 PubMed:与8-异戊烯基柚皮素生产者表型相关的微生物和饮食因素 Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: 一项针对五十名健康的绝经后白 妇女的饮食干预试验。 a dietary intervention trial with fifty healthy post-menopausal Caucasian women.
已发布 PubMed:马中饮食污染物的尿排泄。 Urinary excretion of dietary contaminants in horses.
已发布 PubMed:咖啡因生物传感器的开发。 Development of a biosensor for caffeine.
已发布 PubMed:感染和厌食。 Infection and anorexia.
已发布 PubMed:抗菌概述 Overview of antibacterial, 抗毒素 antitoxin, 抗 物质 antiviral, 和茶黄酮和茶的抗真菌活性。 and antifungal activities of tea flavonoids and teas.
已发布 PubMed:通过定量研究和感官实验对可可豆粒(可可豆)味道的分子定义。 Molecular definition of the taste of roasted cocoa nibs (Theobroma cacao) by means of quantitative studies and sensory experiments.
已发布 PubMed:茶儿茶素,茶黄素和茶提取物对蜡状芽孢杆菌的抗菌活性。 Antimicrobial activities of tea catechins and theaflavins and tea extracts against Bacillus cereus.
已发布 PubMed:己酮可可碱 Pentoxifylline in ALS: 双盲 a double-blind, 随机的 randomized, 多中心 multicenter, 安慰剂对照试验。 placebo-controlled trial.
已发布 PubMed:在癌症期间细胞因子在肌肉消耗中的关键作用。 The pivotal role of cytokines in muscle wasting during cancer.
已发布 PubMed:可可豆粒(可可豆)的感官引导分解和味觉活性多酚的结构测定。 Sensory-guided decomposition of roasted cocoa nibs (Theobroma cacao) and structure determination of taste-active polyphenols.
已发布 PubMed:固相紫外检测系统测定甲基黄嘌呤。 Solid-phase ultraviolet sensing system for determination of methylxanthines.
已发布 PubMed:评估可可和咖啡衍生的甲基黄嘌呤作为控制害虫土狼的有毒物质。 Evaluation of cocoa- and coffee-derived methylxanthines as toxicants for the control of pest coyotes.
已发布 PubMed:巧克力中咖啡因和可可碱增强作用。 Reinforcing effects of caffeine and theobromine as found in chocolate.
已发布 PubMed:基于使用核磁共振和多元数据分析的代谢组学指纹对冬青属物种进行分类。 Classification of Ilex species based on metabolomic fingerprinting using nuclear magnetic resonance and multivariate data analysis.
已发布 PubMed:尿酸或膀胱中的1-甲基尿酸会增加血清葡萄糖 Uric acid or 1-methyl uric acid in the urinary bladder increases serum glucose, 胰岛素 insulin, 真正的true triglyceride, 和wistar大鼠体内的总胆固醇水平。 and total cholesterol levels in Wistar rats.
已发布 PubMed:植物生物化学 Plant biochemistry: 天然脱咖啡因的阿拉伯咖啡。 a naturally decaffeinated arabica coffee.
已发布 PubMed:美国成年 的营养饮食来源 Dietary sources of nutrients among US adults, 1994年至1996年。 1994 to 1996.
已发布 PubMed:咖啡因的测定 Determination of caffeine, theobromine, 和茶碱标准参考物质2384中 and theophylline in standard reference material 2384, 烘焙巧克力 baking chocolate, 使用反相液相色谱。 using reversed-phase liquid chromatography.
已发布 PubMed:hplc-msn分析绿茶和红茶中的酚类化合物和嘌呤生物碱。 HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea.
已发布 PubMed:农学变量对在30摄氏度和175巴下CO2提取获得的伴侣茶叶提取物成分的影响。 Influence of agronomic variables on the composition of mate tea leaves (Ilex paraguariensis) extracts obtained from CO2 extraction at 30 degrees C and 175 bar.
已发布 PubMed:赖索茶碱 Lisofylline, 新型抗炎药 a novel anti-inflammatory agent, 在体内和体外增强葡萄糖刺激的胰岛素分泌 enhances glucose-stimulated insulin secretion in vivo and in vitro: 糖尿病前期和正常大鼠的研究。 studies in prediabetic and normal rats.
已发布 PubMed:(1)h nmr光谱分析代谢产物进行绿茶质量评估 Metabolite profiling using (1)H NMR spectroscopy for quality assessment of green tea, 茶花(山茶)。 Camellia sinensis (L.).
已发布 PubMed:成分对非洲爪蟾卵母细胞中表达的gaba(a)受体应答的影响。 Effects of coffee components on the response of GABA(A) receptors expressed in Xenopus oocytes.
已发布 PubMed:怀孕小鼠的巧克力喂养会影响其后代的四肢长度。 Chocolate feeding of pregnant mice influences length of limbs of their progeny.
已发布 PubMed:生产不含咖啡因的咖啡植物。 Producing decaffeinated coffee plants.
已发布 PubMed:高效液相色谱法同时测定各种食品添加剂 [Simultaneous determination of various food additives by high performance liquid chromatography].
已发布 PubMed:枯否细胞和tnf-α在单苦瓜碱和细菌脂多糖诱导的肝损伤中的作用。 The role of Kupffer cells and TNF-alpha in monocrotaline and bacterial lipopolysaccharide-induced liver injury.
已发布 PubMed:标准参考材料2384烘焙巧克力中营养物浓度的数值分配。 Value assignment of nutrient concentrations in standard reference material 2384 baking chocolate.
已发布 PubMed:己酮可可碱抑制公猪精液碱性磷酸酶活性 Inhibition of alkaline phosphatase activity of boar semen by pentoxifylline, caffeine, 和茶碱。 and theophylline.
已发布 PubMed:内毒素性葡萄膜炎中t淋巴细胞亚型的特征和己酮可可碱治疗效果。 Characterization of T lymphocyte subtypes in endotoxin-induced uveitis and effect of pentoxifylline treatment.
已发布 PubMed:咖啡因增强了尼古丁对大鼠的歧视性刺激作用。 Caffeine potentiates the discriminative-stimulus effects of nicotine in rats.
已发布 PubMed:从瓜拉纳种子中提取甲基黄嘌呤 Extraction of methylxanthines from guaraná seeds, 哑光叶子 maté leaves, 以及使用超临界二氧化碳和乙醇的可可豆。 and cocoa beans using supercritical carbon dioxide and ethanol.
已发布 PubMed:最早的玛雅文明使用可可粉。 Cacao usage by the earliest Maya civilization.
已发布 PubMed:研究儿茶素和黄嘌呤茶的地理特征 Study of catechin and xanthine tea profiles as geographical tracers.
已发布 PubMed:草鱼胆粉的短期毒性 Short-term toxicity of grass carp bile powder, 大鼠中的5α-cyprinol和5α-cyprinol硫酸盐。 5alpha-cyprinol and 5alpha-cyprinol sulfate in rats.
已发布 PubMed:同时测定 造甜味剂 Simultaneous determination of artificial sweeteners, 防腐剂 preservatives, caffeine, 食品和药物制剂中的可可碱和茶碱离子色谱分析。 theobromine and theophylline in food and pharmaceutical preparations by ion chromatography.
已发布 PubMed:Food of the gods gods as 凡 mortals' 药物 medicine: 巧克力和可可产品的用途。 the uses of choclate and cacao products.
已发布 PubMed:糖的发育变异 Developmental variation of sugars, 羧酸 carboxylic acids, 嘌呤生物碱 purine alkaloids, 脂肪酸 fatty acids, 成熟过程中的内毒素和内蛋白酶活性。种子。 and endoproteinase activity during maturation of Theobroma cacao L. seeds.
已发布 PubMed:乙醇和吲哚美辛给药后胃脂肪酶活性的变化 Changes of gastric lipase activity after ethanol and indomethacin administration: 别嘌呤醇预处理的影响 influence of pretreatment with allopurinol, 己酮可可碱和左旋多巴。 pentoxifylline and L-DOPA.
已发布 PubMed:改进的高效液相色谱法测定可可和可可制品中的可可碱和咖啡因。 Improved high-performance liquid chromatography method to determine theobromine and caffeine in cocoa and cocoa products.
已发布 PubMed:整合抗肿瘤坏死因子疗法治疗炎性肠病 Integrating anti-tumor necrosis factor therapy in inflammatory bowel disease: 当前和未来的观点。 current and future perspectives.
已发布 PubMed:南美草药制剂对超重患者的减肥和胃排空延迟。 Weight loss and delayed gastric emptying following a South American herbal preparation in overweight patients.
已发布 PubMed:咖啡因诱发的心律不齐 Caffeine-induced cardiac arrhythmia: 保健食品存在无法识别的危险。 an unrecognised danger of healthfood products.
已发布 PubMed:周围动脉疾病的医疗管理。 Medical management of peripheral arterial disease.
已发布 PubMed:化学风险评估的不确定因素。 cyp1a2探针底物的药代动力学中的 类变异性。 Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates.
已发布 PubMed:化学风险评估的不确定因素 Uncertainty factors for chemical risk assessment: 种间差异的 cyp1a2底物的体内药代动力学和代谢。 interspecies differences in the in vivo pharmacokinetics and metabolism of human CYP1A2 substrates.
已发布 PubMed:摄入羟cut后癫痫发作活动和无反应。 Seizure activity and unresponsiveness after hydroxycut ingestion.
已发布 PubMed:胞质黄嘌呤氧化还原酶介导的大鼠乳腺组织中乙醇生物活化为乙醛和自由基。其在醇促进的乳腺癌中的潜在作用。 Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer.
已发布 PubMed:细菌脂多糖通过依赖于肿瘤坏死因子α的机制增强大鼠黄曲霉毒素b1的肝毒性。 Bacterial lipopolysaccharide enhances aflatoxin B1 hepatotoxicity in rats by a mechanism that depends on tumor necrosis factor alpha.
已发布 PubMed:西洛他唑抑制腺苷摄取并增强缺血诱导的间质腺苷增加 Inhibition of adenosine uptake and augmentation of ischemia-induced increase of interstitial adenosine by cilostazol, 一种治疗间歇性lau行的药物。 an agent to treat intermittent claudication.
已发布 PubMed:己酮可可碱在体内的药代动力学狗口服和静脉内给药后。 Pharmacokinetics of pentoxifylline in dogs after oral and intravenous administration.
已发布 PubMed:选定的尼日利亚饮料中的咖啡因和可可碱含量。 Caffeine and theobromine levels in selected Nigerian beverages.
已发布 PubMed:在长期食物限制方案下静脉内给药后,咖啡因的剂量依赖性药代动力学。 Dose independent pharmacokinetics of caffeine after intravenous administration under a chronic food-limited regimen.
已发布 PubMed:巧克力糖衣和涂层产品中的咖啡因和可可碱含量。 Caffeine and theobromine levels in chocolate couverture and coating products.
已发布 PubMed:红外反射光谱技术在绿茶中生物碱和酚类物质同时预测中的应用 Application of near-infrared reflectance spectroscopy to the simultaneous prediction of alkaloids and phenolic substances in green tea leaves.
已发布 PubMed:使用超临界co(2)从Maté(paraxariguensis)中提取嘌呤生物碱。 Extraction of purine alkaloids from maté (Ilex paraguariensis) using supercritical CO(2).
已发布 PubMed:改进的高效液相色谱法,使用聚乙烯基聚吡咯烷酮预柱,快速分析茶叶中的甲基化黄嘌呤。 Rapid analysis of methylated xanthines in teas by an improved high-performance liquid chromatographic method using a polyvinylpolypyrroridone pre-column.
已发布 PubMed:己酮可可碱和α-生育酚的结合显着消退大剂量伽马射线引起的皮下纤维化 Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: 实验研究。 an experimental study.
已发布 PubMed:热水或可可粉灰溶液处理的可可豆饼对肉鸡的营养价值。 Nutritive value of hot water- or cocoa-pod ash solution-treated cocoa bean cake for broiler chicks.
已发布 PubMed:肿瘤坏死因子α的抑制作用会改变小鼠对鸟分枝杆菌复合体感染的抵抗力。 Inhibition of tumor necrosis factor alpha alters resistance to Mycobacterium avium complex infection in mice.
已发布 PubMed:一氧化氮缺乏症 Nitric oxide deficiency, 明串球菌活化 leukocyte activation, 以及由此产生的局部缺血对于糖尿病性视网膜病变/橙花病变的发病机理至关重要-抗氧化剂的预防潜力 and resultant ischemia are crucial to the pathogenesis of diabetic retinopathy/neuropathy--preventive potential of antioxidants, 必需脂肪酸 essential fatty acids, 铬 chromium, 银杏内酯 ginkgolides, 和己酮可可碱。 and pentoxifylline.
已发布 PubMed:液相色谱法测定含有瓜拉那的草药制剂中的甲基黄嘌呤和儿茶素。 Liquid chromatographic determination of methylxanthines and catechins in herbal preparations containing guaraná.
已发布 PubMed:胶束电动毛细管电泳法测定咖啡因及其代谢物 Determination of caffeine and its metabolites by micellar electrokinetic capillary electrophoresis.
已发布 PubMed:咖啡因和可可碱毒性的最新进展 Recent advances in caffeine and theobromine toxicities: 回顾。 a review.
已发布 PubMed:咖啡因和相关甲基黄嘌呤在抗坏血酸和多酚驱动的芬顿型氧化中的氧化。 Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations.
已发布 PubMed:小麦粉和全脂或脱脂发酵可可粉的面包的蛋白质谱和感官特性。 Protein profiles and organoleptic properties of bread from wheat flour and full-fat or defatted fermented cocoa bean powder.
已发布 PubMed:慢性食物限制条件下的口服和ip咖啡因药代动力学。 Oral and IP caffeine pharmacokinetics under a chronic food-limitation condition.
已发布 PubMed:中期肝脏生物测定中咖啡及其相关化合物潜在的致癌性分析。 Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats.
已发布 PubMed:绿茶组成 Green tea composition, 消费 consumption, 和多酚化学。 and polyphenol chemistry.
已发布 PubMed:乳腺癌和甲基黄嘌呤的食用。 Breast cancer and methylxanthine consumption.
已发布 PubMed:给予颗粒食物污染的马尿中可可碱排泄量。 Urinary excretion of theobromine in horses given contaminated pelleted food.
已发布 PubMed:甲基黄嘌呤对牛奶体积和成分的影响 The effect of methylxanthines on milk volume and composition, 和幼鼠的成长。 and growth of rat pups.
已发布 PubMed:饲喂含有可可豆壳的复合荜澄茄/山苍子体后,纯种赛马中可可碱排泄-确定马尿中的阈值。 The excretion of theobromine in Thoroughbred racehorses after feeding compounded cubes containing cocoa husk--establishment of a threshold value in horse urine.
已发布 PubMed:黄嘌呤对大鼠泌乳性能的影响 Effect of methylxanthines on lactational performance of rats.
已发布 PubMed:使用增香食品改善老年患者的营养状况。 Use of flavor-amplified foods to improve nutritional status in elderly patients.
已发布 PubMed:甲基黄嘌呤 Methylxanthines: 对 类的毒性。 3.可可碱 toxicity to humans. 3. Theobromine, 对黄嘌呤和甲基黄嘌呤的联合作用。 paraxanthine and the combined effects of methylxanthines.
已发布 PubMed:甲基黄嘌呤 Methylxanthines: 对 类的毒性。 1.toxicity to humans. 1. Theophylline.
已发布 PubMed:咖啡和茶中咖啡因摄入量的变异性 Variability in caffeine consumption from coffee and tea: 对于流行病学研究可能具有重要意义。 possible significance for epidemiological studies.
已发布 PubMed:营养因素对男性双胞胎性激素水平的影响。 The effect of nutritional factors on sex hormone levels in male twins.
已发布 PubMed:咖啡因和可可碱遗传毒性和致癌性评估。 Genotoxicity and carcinogenicity assessments of caffeine and theobromine.
已发布 PubMed:己酮可可碱对wrb抗原的影响 Effect of pentoxifylline on Wrb antigen.
已发布 PubMed:可可碱和咖啡因的遗传毒性评估。 Evaluation of the genotoxicity of theobromine and caffeine.
已发布 PubMed:围产期评估 Evaluation of the perinatal, 可可粉和可可碱对sprague-dawley / cd大鼠的产后致畸作用。 postnatal and teratogenic effects of cocoa powder and theobromine in Sprague-Dawley/CD rats.
已发布 PubMed:对新西兰白兔中可可粉和可可碱致畸的评估 Evaluation of the teratogenic potential of cocoa powder and theobromine in New Zealand White rabbits.
已发布 PubMed: 甲基黄嘌呤和腺苷类似物在松鼠猴中调节氯地西oxide的行为作用。
已发布 PubMed:猴子长期食用咖啡因的命运(猕猴)。 The fate of chronically consumed caffeine in the monkey (Macaca fascicularis).
已发布 PubMed:己酮可可碱 Pentoxifylline in ALS: 一种间歇性lau行的新药。 a new agent for intermittent claudication.
已发布 PubMed:抑制咖啡因及其代谢产物对l-苯基异丙基腺苷(l-pia)行为的影响。 Antagonism of the behavioral effects of L-phenylisopropyladenosine (L-PIA) by caffeine and its metabolites.
已发布 PubMed:高效液相色谱法测定可可碱 High-performance liquid chromatographic determination of theobromine, 食品中的茶碱和咖啡因。 theophylline and caffeine in food products.
已发布 PubMed:饮食中咖啡因和可可碱在大鼠中的比较毒性。 Comparative toxicities of dietary caffeine and theobromine in the rat.
已发布 PubMed:茶 tea: 该工厂及其制造;化学和饮料的消费。 the plant and its manufacture; chemistry and consumption of the beverage.
已发布 PubMed:甲基黄嘌呤定量分析方法。 Analytical methods for quantitation of methylxanthines.
已发布 PubMed:可可和巧克力产品的甲基黄嘌呤成分和消费方式。 Methylxanthine composition and consumption patterns of cocoa and chocolate products.
已发布 PubMed:饮食中甲基黄嘌呤的中枢橙花系统药理学。 Central nervous system pharmacology of the dietary methylxanthines.
已发布 PubMed:可可碱新陈代谢。 Theobromine metabolism.
已发布 PubMed:收获季节对两种可可和壳部分的生子叶和发酵子叶组成的影响 [Effect of the harvest season on the composition of raw and fermented cotyledons of 2 varieties of cacao and shell fractions].
已发布 PubMed:咖啡因的影响 Effects of caffeine, 茶碱和可可碱对大鼠有计划的控制反应。 theophylline and theobromine on scheduled controlled responding in rats.
已发布 PubMed:通过微生物和哺乳动物系统检查可可的遗传毒性。 Genotoxicity of cocoa examined by microbial and mammalian systems.
已发布 PubMed:[影响 Effect of 甲基黄嘌呤 甲基黄嘌呤 methyl黄嘌呤 黄嘌呤 xanthines on 尿的 urinary 前列腺素 prostaglandin E excretion of 老鼠 rats 敏锐地 急性 acutely 已加载 loaded with 盐 salt and 水 water (author's 翻译 transl)].
已发布 PubMed:茶的生化和技术。 The biochemistry and technology of tea manufacture.
已发布 PubMed:可可碱在大鼠体内的代谢途径以及 类尿液中两种新代谢物的鉴定。 Metabolic pathway of theobromine in the rat and identification of two new metabolites in human urine.
已发布 PubMed:影响血浆中未酯化脂肪酸浓度的药物和激素对大鼠血浆和脑中色氨酸影响 Effects on plasma and brain tryptophan in the rat of drugs and hormones that influence the concentration of unesterified fatty acid in the plasma.
已发布 PubMed:嘌呤衍生物香草醛和某些单宁物质对仓鼠龋的影响。与食物消费和动物生长有关的龋齿。 Effect on hamster caries by purine derivatives vanillin and some tannin-containing materials. Caries in relation to food consumption and animal growth.
已发布 PubMed:尿中可可碱及其代谢物的测定 [Determination of Theobromine and its metabolites in urine].
已发布 PubMed:植物油脂中维生素e的含量。 VITAMIN E CONTENT OF VEGETABLE OILS AND FATS.
 
笔记 Notes:
0).; ;伯脂肪酸酰胺(r-co-nh2)是一类化合物,最近才从生物来源中分离出来并加以表征。关于这些脂质酰胺在生物系统中如何产生和降解的关键问题仍然存在。 (pmid 15282088); ;脂肪酸酰胺在于与内源性大麻素竞争与酶活性位点的结合,从而增加内源性大麻素的浓度 the principle alkaloid in theobroma cacao (the cacao bean) and other plants. a xanthine alkaloid that is used as a bronchodilator and as a vasodilator. it has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. it has practically no stimulant effect on the central nervous system. it was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (from martindale, 额外的药典 the extra pharmacopoeia, 第30版 30th ed, pp1318-9)组成。茶叶(茶花茶) pp1318-9) Constit. of tea leaves (Camellia thea), 可可 cocoa Theobroma cacao, cola 坚果 nut (可乐 Cola acuminata) and 瓜拉那 guarana (保利尼亚 Paullinia cupana); flavouring 成分 ingredient with a bitter 味道 taste 3,fda第173部分-供 类食用的食品中允许的次要直接食品添加剂b子部分-酶制剂和微生物sec。 173.160念珠菌guilliermondii.fda第173部分-供 类食用的食品中允许的次要直接食品添加剂b-酶制剂和微生物sec。 173.165解脂假丝酵母(fda)173部分-供 类食用的食品中允许使用的次要直接食品添加剂c-溶剂 7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, 额外的药典 the extra pharmacopoeia, 第30版 30th ed, pp1318-9)-pubchem;作为甲基黄嘌呤 pp1318-9) -- Pubchem; As a methylated xanthine, 十一碳烯醛十一碳烯醛十一碳烯醛十一碳烯10-en-1-al十一碳烯-10醛十一碳烯醛天然10-十一碳烯-1-al1-十一碳烯醛-10al10-十一碳烯醛10-十一碳烯醛(醛c-11十一碳烯醛)十一碳烯10 bri(十一碳烯醛。)10-十一碳烯醛十一碳烯醛10-十一碳烯醛10-十一碳烯醛十一碳烯醛 theobromine is a potent Cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitor; this means that it helps prevent the enzyme phosphodiesterase from converting the active cAMP to an inactive form. cAMP works as a second messenger in many hormone- and neurotransmitter-controlled metabolic systems, 如糖原分解。当营地的失活被可可碱等化合物抑制时 such as the breakdown of glycogen. When the inactivation of cAMP is inhibited by a compound such as theobromine, 刺激营地产生的橙花递质或激素的作用寿命更长。最终结果通常是刺激作用。因为它既是心肌兴奋剂又是血管扩张剂 the effects of the neurotransmitter or hormone which stimulated the production of cAMP are much longer lived. The net result is generally a stimulatory effect.; As it is a myocardial stimulant as well as a vasodilator, 它增加了心跳 it increases heartbeat, 但它也会扩张血管 yet it also dilates blood vessels, 导致血压降低。然而 causing a reduced blood pressure. However, 最近发表的一篇论文表明,血压下降可能是由黄烷醇引起的。此外 a recent paper published suggested that the decrease in blood pressure may be caused by flavanols. Furthermore, 它的引流作用使其可用于治疗心力衰竭 its draining effect allows it to be used to treat cardiac failure, 可能是由于过多的积液引起的。即使没有饮食 which can be caused by an excessive accumulation of fluid.; Even without dietary intake, 可可碱可能在 体中发生,因为它是 体内咖啡因代谢的产物,咖啡因在肝脏中代谢为10%可可碱 theobromine may occur in the body as it is a product of the human metabolism of caffeine which is metabolised in the liver into 10% theobromine, 4%茶碱 4% theophylline, 和80%的黄嘌呤。在医学上 and 80% paraxanthine.; In medicine, 它用作利尿剂 it is used as a diuretic, 血管扩张药 vasodilator, 和心肌兴奋剂。前列腺癌和可可碱之间可能存在关联。 -维基百科;它是可可和巧克力中发现的主要生物碱 and myocardial stimulant. There is a possible association between prostate cancer and theobromine. -- Wikipedia; It is the primary alkaloid found in cocoa and chocolate, and is one of the 原因 原因 causes for 巧克力 chocolate's 提升情绪 心情 mood-elevating 效果 影响 effects. The 量 amount 在巧克力中发现 found in chocolate is small 足够 enough that 巧克力 chocolate can be 安全地 safely 已消耗 消耗 consumed by by 类 的 humans in 大 large 数量 quantities, 但是可可碱代谢较慢的动物 but animals that metabolize theobromine more slowly, 例如猫和狗 such as cats and dogs, 容易消耗足够的巧克力以引起巧克力中毒。 -维基百科;可可碱是甲基黄嘌呤家族的一种苦味生物碱 can easily consume enough chocolate to cause chocolate poisoning. -- Wikipedia; Theobromine is a bitter alkaloid of the methylxanthine family, 其中也包括类似的化合物茶碱和咖啡因。尽管它的名字 which also includes the similar compounds theophylline and caffeine. Despite its name, 该化合物不含溴。可可碱衍生自 the compound contains no bromine.Theobromine is derived from Theobroma, 可可树的属 the genus of the cacao tree, 哪一个 which is 组成 composed of the 希腊语 Greek roots theo ("神 God") and broma ("food"), 含义 meaning "food of the gods gods". -- 维基百科 Wikipedia; Theobromine is a 贡献 contribut buting 因子 factor in acid 反流 reflux 因为 be原因 cause it 放松 relaxes the 食道的 esophageal 括约肌 sphincter 肌肉 muscle, 允许胃酸进入食道。 -维基百科;可可碱是一种经常与咖啡因混淆的兴奋剂。可可碱与咖啡因对 体的影响大不相同。可可碱是水不溶性的 allowing stomach acid access to the esophagus. -- Wikipedia; Theobromine is a stimulant frequently confused with caffeine. Theobromine has very different effects on the human body from caffeine; Theobromine is a water insoluble, 结晶的 crystalline, 苦粉颜色已被列为白或无色。它有一个类似的 bitter powder; the colour has been listed as either white or colourless. It has a similar, 但较少 but lesser, 对咖啡因的影响 effect to caffeine, 使它成为一个较小的同源物。可可碱是茶碱和对黄嘌呤的异构体。可可碱被归类为二甲基黄嘌呤 making it a lesser homologue. Theobromine is an isomer of theophylline as well as paraxanthine. Theobromine is categorized as a dimethyl xanthine, 这意味着它是具有两个甲基的黄嘌呤。可可碱 which means it is a xanthine with two methyl groups.; Theobromine, 也称为黄药 also known as xantheose, 是可可植物的苦味生物碱 is a bitter alkaloid of the cacao plant, 在巧克力中发现 found in chocolate, 以及可可碱来源制成的多种无巧克力食品,包括茶树的叶子 as well as in a number of chocolate-free foods made from theobromine sources including the leaves of the tea plant, 可乐或可乐坚果 the kola or cola nut, 和巴西莓[需要引证]。它属于甲基黄嘌呤类化合物 and acai berries[citation needed]. It is in the methylxanthine class of chemical compounds, 其中也包括类似的化合物茶碱和咖啡因。 (在咖啡因中 which also includes the similar compounds theophylline and caffeine. (In caffeine, 唯一的区别是可可碱nh组是n-ch3组。) the only difference is that the NH group of theobromine is an N-CH3 group.) Despite its name, 该化合物不含溴吗?可可碱衍生自 the compound contains no bromine ? theobromine is derived from Theobroma, 可可树属的名称 the name of the genus of the cacao tree, (哪一个 which 本身 itself is 制作 made up of the 希腊语 Greek roots theo ("神 God") and brosi brosi ("food"), 含义 meaning "food of the gods gods") with the 后缀 suffix -ine -ine 给定 given to 生物碱 生物碱 alkaloids and other 基本的 basic 含氮 nitrogen-包含 containing compounds.; 而 While theobromine and caffeine are 类似 similar in that 他们 they are 有关 related 生物碱 生物碱 alkaloids, 可可碱对环核苷酸磷酸二酯酶的抑制作用和对腺苷受体的拮抗作用均较弱。因此 theobromine is weaker in both its inhibition of cyclic nucleotide phosphodiesterases and its antagonism of adenosine receptors. Therefore, 可可碱对 中枢橙花系统的影响比咖啡因小。然而 theobromine has a lesser impact on the human central nervous system than caffeine. However, 可可碱可更大程度地刺激心脏。[需要引用]可可碱不那么容易上瘾 theobromine stimulates the heart to a greater degree.[citation needed] While theobromine is not as addictive, it 已 has been been 被引 cited as 可能 possibly 引起 ca使用 using 瘾 addiction to 巧克力 chocolate. Theobromine 已 has 也 also been been identified as one of the compounds 贡献 contribut buting to 巧克力 chocolate's 享有盛誉 reputed role as an 春药 aphrodisiac.; it is a 轻度 mild, 具有改善情绪的持久性兴奋剂 lasting stimulant with a mood improving effect, 而咖啡因具有很强的 whereas caffeine has a strong, 立即生效并增加压力。 -维基百科 immediate effect and increases stress. -- Wikipedia
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