紫苏醇 Perillyl Alcohol
p-mentha-1,8-dien-7-ol

供应商赞助商 Supplier Sponsors

  • BOC Sciences
    最好的化学品供应商 Best of Chemicals Supplier
    研究化学品和生化试剂(包括抑制剂)的优质供应商 Quality supplier of research chemicals and biochemicals including inhibitors, 建筑模块 building blocks, gmp产品 GMP Products, 杂质和代谢物 impurities and metabolites, 兽医用api APIs for Veterinary, 天然化合物 Natural Compounds, adcs ADCs, 干细胞分子和手性化合物。 Stem Cell Molecule and chiral compounds.
    卡波普® ultrez 21聚合物是我们用途最广泛的个 护理聚合物。它是一种疏水改性的交联丙烯酸酯共聚物,旨在有效地增稠 BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, 同位素标记服务 Isotope Labeling Service, 手性合成与拆分 Chiral Synthesis and Resolution, 生物共轭 Bioconjugation, 聚乙二醇化服务 PEGylation services, 分析服务。 analytical services.
    boc sciences是bocsci inc。的品牌。我们利用我们在发展领域的广泛业务 BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, 制造业 manufacturing, 行销 marketing, 和分销,以帮助您根据不断变化的优质化学品需求制定最明智的决策。我们完整的cro服务套件涵盖了整个分子开发流程,包括用于目标识别的合同研究 and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, 建筑模块 building blocks, 化合物合成 compound synthesis, 生化和细胞分析 biochemical and cellular analysis, 临床前动物试验 preclinical animal tests, 和临床研究。 and clinical studies.
    电子邮件 Email:行销 marketing
    我们的电子邮件 US Email:行销 marketing
    电子邮件 Email:Sales
    我们的电子邮件 US Email:Sales
    语音 Voice:
    1-631-504-6093
    传真 Fax:
    1-631-614-7828
    我们的声音 US Voice:
    1-631-504-6093
    我们传真 US Fax:
    1-631-614-7828
    Europe44-203-286-1088
    脸书 Facebook
    推特 Twitter
    领英 Linkedin
    博客 Blog
    下载这个软件! Get the App!
    产品 Product(s):
    536-59-4二氢枯烯醇> 98% 536-59-4 Dihydrocuminyl alcohol >98%
  • Indukern F&F
    对质量的承诺 Commitment to quality
    idukern f& f成分是您芳香和增香成分的合作伙伴。 Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.
    indukern f& f特别注重其为客户提供的服务质量 Indukern F&F focuses in particular on the service it offers its clients in terms of quality, 快速和直接的咨询服务,有1600多种不同的库存产品,可立即发货 speed and direct consultancy with more than 1600 different products in stock ready for prompt shipment: 芳香化学品 Aromachemicals, 精油和天然分离物。 Essential Oils and Natural Isolates.
    电子邮件 Email:信息 Info
    电子邮件 Email:luciana soares(巴西) Luciana Soares (Brazil)
    电子邮件 Email:加布里埃拉·加西亚(墨西哥) Gabriela Garcia (Mexico)
    电子邮件 Email:jorge eduardo clavijo(哥伦比亚) Jorge Eduardo Clavijo (Colombia)
    语音 Voice:
    +34 93 506 91 00
    传真 Fax:
    +34 93 506 91 95
    服务 Services
    质量 Quality
    设备 Facilities
    产品清单 Products List:视图 View
    产品 Product(s):
    紫苏醇 Perillyl Alcohol
  • Jiangyin Healthway
    独立成分供应商 Independent Ingredients Supplier
    我们提供从毫克到公吨的定制合成和合同制造。 We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
    江阴健威国际贸易有限公司 Jiangyin Healthway International Trade Co., 公司 Inc. is a 香基/香型的 professional company, 主要从事制造和出口香气化学品 main engaged in manufacturing and exporting aroma chemicals ,食品添加剂 food additives , 化妆品成分 cosmetic ingredient ,医药中间体其他精细化学品;特别是在芳香化学品上 pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , 作为杂环和硫磺香气化合物的主要制造商 as the major manufacturer of heterocyclic and sulphur aroma compounds , 我们是中国香精香料行业领先的独立配料供应商 we are the leading independent ingredients supplier to the flavour and fragrance industries in China, 可以提供数百种不同质量的芳香化学品。 can offer hundreds of different high quality aroma chemicals.
    电子邮件 Email:信息 Info
    电子邮件 Email:Sales
    语音 Voice:
    86-510-86023169
    传真 Fax:
    86-510-86023170
    Mobile0086-13093133011
    服务 Services
    生化 Biochemical
    天然食用色素 Natural Food Colour
    新功能食品成分 New functional food ingredients
    产品 Product(s):
    hlw-fc042紫苏醇 HLW-FC042 Perillyl Alcohol
  • Lluch Essence
    致力于销售和分销的家族公司 A family company dedicated to sales and distribution
    灵活性 Flexibility, 可用性 availability, 价格和质量。 price and quality.
    灵活性 Flexibility, 可用性 availability, 价格和质量使lluch精华s.l.关于精油和香精化学品的欧洲参考文献之一 price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, 现在它已在世界范围内广为 知。 and it is now well known all around the world.
    电子邮件 Email:信息 Info
    语音 Voice:
    34 93 379 38 49
    传真 Fax:
    34 93 370 65 04
    领英 Linkedin
    产品 Product(s):
    紫苏醇 Perillyl Alcohol
  • Penta International
    化学创新 Chemistry innovation
    在五角 At Penta, 我们的产品和服务可帮助企业更好地开展业务。 our products and services help businesses do business better.
    超过30年 For over 30 years, penta制造业公司在全球化学创新和应用中扮演着越来越重要的角色。作为行业领导者 Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, penta继续为几乎每个商业领域开拓基于化学的解决方案。我们的产品和香基/香型知识帮助推动了包括调味剂在内的数十种商业应用的技术进步 Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, 染色 coloring, 香料和化学工艺。 fragrances and chemical processes.
    我们的电子邮件 US Email:技术服务 Technical Services
    我们的电子邮件 US Email:Sales
    我们的声音 US Voice:
    (973) 740-2300
    我们传真 US Fax:
    (973) 740-1839
    产品 Product(s):
    16-14700紫苏醇 16-14700 PERILLA ALCOHOL
  • Synerzine
    革新。定制。香气成分。 Innovation. Customization. Aroma Ingredients.
    synerzine是香精和香料成分的领先供应商。 Synerzine is a leading supplier of flavor and fragrance ingredients.
    synerzine表示我们已经成长为一个组织所体现的东西-原料之间的协同作用和联系 Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, 技术 technology, 以及最终产品。我们经验丰富的团队热衷于为客户提供他们可以信赖的高质量创新食材。 and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
    建立在我们44年的历史上 Building upon our 44 year history, 锌碘产品由EPA批准使用,并由fda允许。锌碘和贸易;杀真菌剂-除藻剂是巯氧吡啶的锌配合物。锌碘和贸易;杀菌杀藻剂是世界上一些领先的去头皮屑洗发水产品中的活性成分 , 大型产品选择 large product selection, 定制和最高的质量和安全标准。我们为客户提供真正的价值,旨在帮助他们更快地将其产品推向市场。 customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
    我们的电子邮件 US Email:客户服务 Customer Service
    我们的电子邮件 US Email:Sales
    我们的声音 US Voice:
    (404) 524-6744
    我们传真 US Fax:
    (404) 577-1651
    Inquiry
    产品清单 Products List:视图 View
    产品 Product(s):
    w1684紫苏醇 W1684 Perillyl Alcohol
香水典型/定制配方-请咨询我们索取 Fragrance Demo Formulas
Name:(4-丙-1-烯-2-基-1-环己烯基)甲醇 (4-prop-1-en-2-yl-1-cyclohexenyl)methanol
CAS号 CAS Number: 536-59-4Picture of molecule3D/INCHI
ECHA EINECS - REACH 预注册 Pre-Reg:208-639-9
FDA UNII:319R5C7293
nikkaji网站 Nikkaji Web:J11.581I
代号 CoE Number:2024
XlogP3-AA:2.10(est) 2.10 (est)
分子量 Molecular Weight:152.23672000
式 Formula:c10 h16 o C10 H16 O
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
efsa / jecfa评论 EFSA/JECFA Comments:
外消旋体 Racemate
类别 Category:cosmetic, flavor and fragrance agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
谷歌专利 Google Patents:搜索 Search
美国专利 US Patents:搜索 Search
欧盟专利 EU Patents:搜索 Search
pubchem专利 Pubchem Patents:搜索 Search
已发布 PubMed:搜索 Search
NCBI:搜索 Search
jecfa食品调味料 JECFA Food Flavoring:974 p-mentha-1 974 p-mentha-1,8-dien-7-ol
Flavis号码 FLAVIS Number:02.060(旧) 02.060 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:02.060 p-mentha-1 02.060 p-mentha-1,8-dien-7-ol
fema号 FEMA Number:2664 p-mentha-1,8-dien-7-ol
自由贸易区 FDA:不再提供这七种合成调味剂的使用 No longer provide for the use of these seven synthetic flavoring substances
fda mainterm(satf) FDA Mainterm (SATF):536-59-4 ; P-MENTHA-1,8-dien-7-ol 8-DIEN-7-OL
自由贸易区法规 FDA Regulation:
自由贸易区 FDA PART 172 -- FOOD 添加剂 ADDITIVES 允许的 PERMITTED 对于 FOR 直接 DIRec ECT 加成 ADDITION TO FOOD 对于 FOR 的 HUMAN CONSUMPTION
Subpart f--调味 F--调味料 味道 Flavoring 代理商 Agents and 有关 Related Substances
Sec. 172.515 合成的 Synthetic flavoring 物质 substances and adjuvants.
 
物理性质 Physical Properties:
出现 Appearance:无色至浅黄澄清液体(est) colorless to pale yellow clear liquid (est)
化验 Assay: 96.00至100.00 96.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
比重 Specific Gravity:0.95000 to 0.96500 @ 25.00 °C.
磅每加仑-(est)。 Pounds per Gallon - (est).: 7.905 to 8.030
折光率 Refractive Index:1.48800 to 1.50500 @ 20.00 °C.
沸点 Boiling Point: 119.00 to 121.00 °C. @ 11.00 mm 汞 Hg
沸点 Boiling Point: 92.00 to 93.00 °C. @ 760.00 mm 汞 Hg
蒸汽压力 Vapor Pressure:0.006000 毫米汞柱 mm汞 Hg @ 25.00 °C. (est)
闪点 Flash Point:> 230.00° tcc(> 110.00°c。) > 230.00 °F. TCC ( > 110.00 °C. )
logp(o / w) logP (o/w): 3.170
溶于 Soluble in:
 alcohol
 水 water, 471 mg / l @ 25°c(est) 471 mg/L @ 25 °C (est)
不溶于 Insoluble in:
 水 water
 
感官特性 Organoleptic Properties:
气味类型 Odor Type: green
气味强度 Odor Strength:介质 medium
green bois de rose lilac fatty
气味描述 Odor Description:at 100.00 %. green linalool 松油醇 ter松树 pineol fatty
sweet woody aromatic spicy cardamom green cumin orange peel green waxy floral
气味描述 Odor Description:at 1.00 %. sweet , woody, aromatic spicy cardamom and green cumin 喜欢 like with 干的 dried orange peel and green waxy floral nuances
Mosciano, 杰拉德 Gerard, (2009)
风味类型 Flavor Type: woody
sweet woody aromatic spicy cardamom green cumin orange peel green waxy floral
口味描述 Taste Description: at 25.00 百万分之几 ppm. sweet , woody, aromatic spicy cardamom and green cumin 喜欢 like with 干的 dried orange peel and green waxy floral nuances
Mosciano, 杰拉德 Gerard, (2009)
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
CosIng:化妆品数据 cosmetic data
化妆品用途 Cosmetic Uses: 抗菌剂 antimicrobial agents
抗氧化剂 antioxidants
掩蔽剂 masking agents
加香剂 perfuming agents
皮肤保护剂 skin protecting agents
 
供应商 Suppliers:
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
二氢枯烯醇> 98% Dihydrocuminyl alcohol >98%
柑橘及相关精华 Citrus and Allied Essences
紫苏醇 Perillyl Alcohol
市场报告 Market Report
de monchy芳香族 De Monchy Aromatics
二氢枯基异丙醇 dihydro cuminyl alcohol
Indukern F&F
紫苏醇 Perillyl Alcohol
气味 For Odor: 绿 GREEN, 草药 HERBAL
Jiangyin Healthway
紫苏醇 Perillyl Alcohol
新功能食品成分 New functional food ingredients
Lluch Essence
紫苏醇 Perillyl Alcohol
日本萜烯化学品 Nippon Terpene Chemicals
紫苏醇85%或更高 l-Perillyl alcohol 85% up
Penta International
紫苏醇 Perillyl Alcohol
轮回菲希特纳 Reincke & Fichtner
薄荷脑1 p-Mentha-1,8-dien-7-ol
Synerzine
紫苏醇 Perillyl Alcohol
 
安全信息 Safety Information:
欧洲信息 European information :
最重要的危害 Most important hazard(s):
xi-刺激性 Xi - Irritant
r 36/37/38-刺激眼睛 R 36/37/38 - Irritating to eyes, 呼吸系统 respiratory system, and skin.
S 02 - 保持 k Keep out of the 达到 reach of 孩子们 children.
S 24/25 - 避免 Avoid contact with skin and 眼睛 眼睛 eyes.
S 26 - In 案件 case of contact with 眼睛 眼睛 eyes, 冲洗 rinse 立即 immediately with 充裕 plenty of 水 water and 寻求 seek 医疗 medical advice.
S 37/39 - 穿 我们 Wear 适当 suitable 手套 gloves and 眼睛 eye/face 保护 protection.
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
类经验 Human Experience:
4%溶液 4 % solution: 没有刺激或过敏。 no irritation or sensitization.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
口鼠 oral-rat LD50 2100 mg/kg kg
Food and 化妆品 Cosmetics Toxicology. 卷 Vol. 19, pg。 253 Pg. 253, 1981.

皮肤毒性 Dermal Toxicity:
皮肤兔子 skin-rabbit LD50 > 5000 mg/kg kg
Food and 化妆品 Cosmetics Toxicology. 卷 Vol. 19, pg。 253 Pg. 253, 1981.

吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
cosmetic, flavor and fragrance agents
IFRA IFRA 码 Code of 实践 Practice 通知 not Notification of the 49th 修正案 Amendment to the IFRA IFRA 码 Code of 实践 Practice
最高的皮肤香气 maximum skin levels for fine fragrances:
  0.1700 % and are 基于 based on the 假设 assumption that the fragrance 混合物 mixture is 用过的 used at 20% in a 消费者 consumer product (IFRA IFRA 采用 Use 水平 Level 调查 Survey). (IFRA IFRA, 2006)
紫苏醇的使用建议水平最高 Recommendation for perilla alcohol usage levels up to:
  香料浓缩物中的4.000%。 4.0000 % in the fragrance concentrate.
化妆品配方中的使用量 use level in formulae for use in cosmetics:
  0.0200 %
化妆品中的皮肤全身暴露 Dermal Systemic Exposure in Cosmetic Products:
  0.0005 mg / kg kg / day day(IFRA IFRA , 2006)
 
最大化源自调查的每日摄入量(msdi-eu) Maximised Survey-derived Daily Intakes (MSDI-EU): 1.6(微克/ 均/天) 1.6 (μg/capita/day)
最大化源自调查的每日摄入量(msdi-usa) Maximised Survey-derived Daily Intakes (MSDI-USA): 1.00(微克/ 均/天) 1.00 (μg/capita/day)
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): 1500(微克/ /天) 1500 (μg/person/day)
关注点 Threshold of Concern:1800(微克/ /天) 1800 (μg/person/day)
结构类 Structure Class: I
采用 Use 等级 水平 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its 判断 judgments that the 物质 substances are 通常 基因 generally 公认的 recognized as safe (GRAS).
The 专家 Expert 面板 Panel 也 also 发表 publishes 分离 sepa率 rate 广泛 extensive 评论 评论 reviews of scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library
出版编号 publication number: 3
单击此处查看出版物3 Click here to view publication 3
 平均 average 通常 usual 百万分之几 ppm平均 average 最大 maximum 百万分之几 ppm
焙烤食品 baked goods: 10.0000050.00000
饮料(不含醇) beverages(nonalcoholic): 0.500001.00000
醇饮料 beverages(alcoholic): --
早餐麦片 breakfast cereal: --
起司 cheese: --
口香糖 chewing gum: --
调味品/调味品 condiments / relishes: --
糖果烧烤 confectionery froastings: --
蛋制品 egg products: --
脂肪/油 fats / oils: --
鱼产品 fish products: --
冷冻乳制品 frozen dairy: 0.500001.00000
水果冰 fruit ices: 0.500001.00000
明胶/布丁 gelatins / puddings: --
砂糖 granulated sugar: --
肉汁 gravies: --
硬糖 hard candy: -20.00000
仿乳制品 imitation dairy: --
速溶咖啡/茶 instant coffee / tea: --
果酱/果冻 jams / jellies: --
肉制品 meat products: --
奶制品 milk products: --
坚果产品 nut products: --
其他谷物 other grains: --
家禽 poultry: --
加工水果 processed fruits: --
加工蔬菜 processed vegetables: --
重构蔬菜 reconstituted vegetables: --
调味料 seasonings / flavors: --
休闲食品 snack foods: --
软糖 soft candy: --
汤类 soups: --
糖替代品 sugar substitutes: --
甜酱 sweet sauces: --
 
根据委员会法规ec EC号的食品类别。 1565/2000(ec , 2000)在fge.06(efsa 2000) in FGE.06 (EFSA, 2002a). 根据 According to the Industry the "正常 normal" use is 定义的 de精细 fined as the 平均 average of 已报告 reported 用法 用法 usages and "最大 maximum use" is 定义的 de精细 fined as the 95th 百分位 percentile of 已报告 reported 用法 用法 usages (e (EFSA, 2002i)。 2002i).
注意 Note: 毫克/千克= 0.001 / 1000 = 0.000001 = 1/1000000 = 百万分之几 ppm
 平均 average 用法 usage mg/kg kg最大 maximum 用法 usage mg/kg kg
乳制品 Dairy products, 不包括02.0(01.0)类产品 excluding products of category 02.0 (01.0): 5.0000010.00000
脂肪和油脂 Fats and oils, 和脂肪乳液(油包水型)(02.0) and fat emulsions (type water-in-oil) (02.0): --
食用冰 Edible ices, 包括果子露和果汁冰糕(03.0) including sherbet and sorbet (03.0): 5.0000010.00000
加工水果(04.1) Processed fruit (04.1): 5.0000010.00000
加工蔬菜(包括蘑菇和真菌) Processed vegetables (incl. mushrooms & fungi, 根与根块茎 roots & tubers, 豆类和豆类) pulses and legumes), 和坚果种子(04.2) and nuts & seeds (04.2): --
糖果(05.0) Confectionery (05.0): 5.0000025.00000
谷物和谷物产品 Cereals and cereal products, 含税面粉根和淀粉块茎 incl. flours & starches from roots & tubers, 脉冲和豆类 pulses & legumes, 不包括面包店(06.0) excluding bakery (06.0): 5.0000010.00000
烘焙用具(07.0) Bakery wares (07.0): 8.0000050.00000
肉和肉制品 Meat and meat products, 包括家禽和野味(08.0) including poultry and game (08.0): --
鱼和鱼制品 Fish and fish products, 包括软体动物 including molluscs, 甲壳类和棘皮类动物(麦克 MCE)(09.0) : --
鸡蛋和蛋制品(10.0) Eggs and egg products (10.0): --
甜味剂 Sweeteners, 包括蜂蜜(11.0) including honey (11.0): --
盐 Salts, 香料 spices, 汤类 soups, 酱料 sauces, 色拉 salads, 蛋白产品 protein products, 等(12.0) etc. (12.0): --
用于特定营养用途的食品(13.0) Foodstuffs intended for particular nutritional uses (13.0): --
不含醇 Non-酒鬼 alcoholic ("柔软的 soft") 饮料 beverages, 不包括乳制品(14.1) excl. dairy products (14.1): 1.000005.00000
含醇的饮料 Alcoholic beverages, 含税无醇和低醇的对口(14.2) incl. alcohol-free and low-alcoholic counterparts (14.2): 0.500001.00000
即食美味(15.0) Ready-to-eat savouries (15.0): --
复合食品(例如砂锅菜) Composite foods (e.g. casseroles, 肉馅饼 meat pies, 百果馅)-无法放在01.0-15.0(16.0)类别中的食物 mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 2.0000010.00000
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

关于调味剂组评估208修订版1的科学意见(fge.208rev1) Scientific Opinion on Flavouring Group Evaluation 208 Revision 1 (FGE.208Rev1): 考虑代表10种脂环族醛的遗传毒性数据 Consideration of genotoxicity data on representatives for 10 alicyclic aldehydes with the a,不饱和 �-unsaturation in ring / 侧链 side-chain and 前体 precursors from chemical 亚组 subgroup 2.2 of
视图 View page or 视图 View pdf

关于调味剂组评估208修订版2的科学意见(fge.208rev2) Scientific Opinion on Flavouring Group Evaluation 208 Revision 2 (FGE.208Rev2): 考虑脂环族醛的遗传毒性数据 Consideration of genotoxicity data on alicyclic aldehydes with a,不饱和 �-unsaturation in ring/侧链 side-chain and 前体 precursors from chemical 亚组 subgroup 2.2 of ge FGE.19
视图 View page or 视图 View pdf

调味组评估的科学见解73 Scientific Opinion on Flavouring Group Evaluation 73, 修订版4(fge.73rev4) Revision 4 (FGE.73Rev4): 考虑脂环族醇 consideration of alicyclic alcohols, 醛类 aldehydes, jecfa评估的酸和相关酯 acids and related esters evaluated by JECFA (第59次和第63次会议)在结构上与小学 (59th and 63rd meeting) structurally related to primary 饱和或不饱和脂环族醇 saturated or unsaturated alicyclic alcohols, 醛类 aldehydes, acids acids and esters 已评估 evaluated by by efsa EFSA in ge FGE.12Rev5
视图 View page or 视图 View pdf

关于调味剂组评估208修订版3的科学意见(fge.208rev3) Scientific Opinion on Flavouring Group Evaluation 208 Revision 3 (FGE.208Rev3): 考虑脂环族醛的遗传毒性数据 Consideration of genotoxicity data on alicyclic aldehydes with a,不饱和 �-unsaturation in ring/侧链 side-chain and 前体 precursors from chemical 亚组 subgroup 2.2 of ge FGE.19
视图 View page or 视图 View pdf

Epi系统 EPI System: 视图 View
临床 Clinicaltrials.gov :search
化学致癌研究信息系统 Chemical Carcinogenesis Research Information System:搜索 Search
癌症引文 Cancer Citations:搜索 Search
毒理学引文 Toxicology Citations:搜索 Search
EPA物质注册服务(tsca TSCA) :536-59-4
EPA ACToR:毒理学资料 Toxicology Data
EPA物质注册服务(SRS) :注册表 Registry
实验室化学安全摘要 Laboratory Chemical Safety Summary :10819
国家过敏和传染病研究所 National Institute of Allergy and Infectious Diseases:Data
德国wgk WGK Germany:2
(4-丙-1-烯-2-基-1-环己烯基)甲醇 (4-prop-1-en-2-yl-1-cyclohexenyl)methanol
chemidplus Chemidplus:0000536594
技术 technology:适用于CAS#536-59-4的os8395000 OS8395000 for cas# 536-59-4
 
参考资料 References:
 (4-丙-1-烯-2-基-1-环己烯基)甲醇 (4-prop-1-en-2-yl-1-cyclohexenyl)methanol
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
加拿大国内分公司。清单 Canada Domestic Sub. List:536-59-4
pubchem(cid) Pubchem (cid):10819
pubchem(sid) Pubchem (sid):134977617
信息基 Pherobase:视图 View
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
CHEBI:视图 View
CHEMBL:视图 View
格尔姆代谢组数据库 Golm Metabolome Database:搜索 Search
嗯bbd UM BBD:搜索 Search
KEGG (GenomeNet):C02452
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB03634
食物 FooDB:FDB014925
出口关税代码 Export Tariff Code:2906.10
典型的g.c. Typical G.C.
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
气味 For Odor
醛 aldehydic
citronellyl oxyacetaldehyde
FL/FR
百合 lily pentanal
FR
穆格 muguet undecadienal
FR
nonanal (aldehyde C-9)
FL/FR
animal
para-
cresyl isobuty率 rate
FL/FR
para-
cresyl phenyl acetate
FL/FR
茴香 anise
星 star
茴香 anise oil CO2 extract
FL/FR
aromatic
aromatic woody citrus floral fragrance
FR
香醋 balsamic
安息香 benzoin 精华/精粹/精萃 absolute 替代者 replacer
FL/FR
芳樟基 linalyl cinnamate
FL/FR
没药 myrrh oil CO2 extract
FL/FR
代没药 opoponax 精华/精粹/精萃 absolute (balsamodendron balsamodendron 卡法尔 kafal)
FL/FR
citrus
benzyl 邻氨基苯甲酸 anthranilate
FR
citrus ocimenol
FR
(Z)-4-
decenal
FL/FR
柠檬 lemon oil 替代者 replacer
FR
Myrmac myrmac aldehyde
FR
苦 bitter
orange peel oil brazil
FL/FR
tetrahydromyrcenol
FR
泥土的 earthy
octyl phenyl acetate
FL/FR
floral
alpha-
amyl 肉桂醛 cinnamaldehyde dimethyl acetal
FL/FR
bois de rose oil brazil
FL/FR
alpha-
butyl 肉桂醛 cinnamaldehyde
FL/FR
citronellyl ethoxalate
FR
可乐醇 coranol (芬美意 Firmenich)
FR
cumin carbinol
FR
仙客来 cyclamen aldehyde / methyl 邻氨基苯甲酸 anthranilate schiff's base
FR
仙客来 cyclamen homoaldehyde
FR
cyclohexyl ethyl alcohol
FL/FR
cyclohexyl propanol
FR
2-
decalinol
FR
dihydrolinalool
FL/FR
3,6-
dimethyl-3-octanol
FL/FR
ethyl linalool
FR
ethyl 芳樟基 linalyl acetal
FR
ethyl 芳樟基 linalyl acetate
FR
ethyl 芳樟基 linalyl ether
FL/FR
(e (E,E)-
法尼醇 farnesol
FL/FR
floral butanal
FR
floral pyranol
FR
小苍兰 freesia acetate
FR
梔子花 gardenia decalone
FR
山楂 hawthorn ethanol
FR
ho leaf oil
FR
ho wood oil
FR
羟柠檬醛 hydroxycitronellal
FL/FR
羟柠檬醛 hydroxycitronellal / methyl 邻氨基苯甲酸 anthranilate schiff's base
FR
羟柠檬醛 hydroxycitronellal diethyl acetal
FL/FR
羟柠檬醛 hydroxycitronellal dimethyl acetal
FL/FR
hydroxycitronellol
FL/FR
jasimia
FR
薰衣草 lavender oil
FL/FR
薰衣草 lavender oil 替代者 replacer
FR
乐leerall
FR
乐leerall / methyl 邻氨基苯甲酸 anthranilate schiff's base
FR
百合 lily propanol
FR
百合 lilyall 百合 lilyall
FR
百合 lilyall 百合 lilyall / methyl 邻氨基苯甲酸 anthranilate schiff's base
FR
dextro-
linalool
FL/FR
laevo-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
芳樟基 linalyl 邻氨基苯甲酸 anthranilate
FL/FR
芳樟基 linalyl benzoate
FL/FR
芳樟基 linalyl propionate
FL/FR
木兰 magnolia cyclohexanol
FR
木兰 magnolia decadienal
FR
methoxycitronellal
FR
2-
methyl octanal
FL/FR
穆格 muguet butanal
FR
穆格 muguet butanol
FR
穆格 muguet carbaldehyde
FR
穆格 muguet carbinol
FL/FR
穆格 muguet carboxaldehyde
FR
穆格 muguet ethanol
FR
穆格 muguet nitrile
FR
穆格 muguet octadienol
FR
穆格 muguet propanol
FR
穆格 muguet shiseol
FL/FR
phenyl glycol diacetate
FR
alpha-
terpinyl 邻氨基苯甲酸 anthranilate
FL/FR
tetrahydrolinalool
FL/FR
依兰 ylang 依兰 ylang 花 flower oil
FL/FR
依兰 ylang 依兰 ylang 花 flower oil CO2 extract
FL/FR
依兰 ylang 依兰 ylang 花 flower oil I
FL/FR
依兰 ylang 依兰 ylang 花 flower oil II
FL/FR
依兰 ylang 依兰 ylang 花 flower oil III
FL/FR
草药 HERBAL
芹菜 apium graveolens 种子 seed oil
FL/FR
胡萝卜 carrot 种子 seed oil (daucus carota ssp. gummifer 钩 hook. fil.) spain
FR
胡萝卜 carrot 种子 seed oil (daucus carota ssp. 最大 maximus (desf desf.) 球 ball)
FR
野生 wild
胡萝卜 carrot 种子 seed oil terpeneless
FL/FR
芹菜 celery ketone
FL/FR
芹菜 celery 种子 seed oil 替代者 replacer
FR
芹菜 celery specialty
FR
dimethyl benzyl 羰基 carbinyl formate
FL/FR
薰衣草 lavender fragrance
FR
薰衣草 lavender specialty
FR
广藿香 patchouli oil 萜烯 terpenes
FR
laevo-
紫苏醛 laevo-perillaldehydeFL/FR
FL/FR
甘草 licorice
甘草 licorice fragrance
FR
海洋的 marine
臭氧 ozone propanal
FR
spicy
多香果粉 allspice berry 精华/精粹/精萃 absolute
FL/FR
cardamom 种子 seed oil CO2 extract
FL/FR
肉桂 cinnamon 皮 bark 精华/精粹/精萃 absolute
FL/FR
肉桂 cinnamon 皮 bark oil (肉桂 cinnamomum zeylanicum) india
FL/FR
肉桂 cinnamon 皮 bark oil ceylon
FL/FR
肉桂 cinnamon leaf oil ceylon
FL/FR
丁香 clove 芽 bud 精华/精粹/精萃 absolute
FL/FR
丁香 clove 芽 bud oil
FL/FR
丁香 clove 芽 bud oil 替代者 replacer
FR
丁香 clove fragrance
FR
丁香 clove leaf oil
FL/FR
丁香 clove stem oil
FL/FR
荜澄茄/山苍子 cubeb oil
FL/FR
月桂树 laurel leaf oil 替代者 replacer
FR
laurus nobilis leaf oil
FL/FR
mace fragrance
FR
mace oil
FL/FR
肉豆蔻 坚果 nutmeg oil 替代者 replacer
FR
肉豆蔻 坚果 nutmeg oleoresin
FL/FR
胡椒 pepper 树 tree berry oil
FL/FR
萜烯 terpenic
hinoki hinoki oil 替代者 replacer
FR
香草 FRvanilla
香草醛烯 vanillylidene acetone
FL/FR
woody
沉香木 agarwood oil (aetoxylon sympetalum)
FR
雪松 cedarleaf oil 替代者 replacer
FR
雪松木 cedarwood oil 西 western red
FR
劳罗 louro b拉斯 rasileiro wood oil
FR
金钟柏 thuja occidentalis leaf oil
FL/FR
用于调味 For Flavor
找不到适合这些的口味组 No flavor group found for these
alpha-
amyl 肉桂醛 cinnamaldehyde dimethyl acetal
FL/FR
dimethyl benzyl 羰基 carbinyl formate
FL/FR
ethyl 芳樟基 linalyl ether
FL/FR
(e (E,E)-
法尼醇 farnesol
FL/FR
laurus nobilis leaf oil
FL/FR
dextro-
linalool
FL/FR
2-
methyl octanal
FL/FR
octyl phenyl acetate
FL/FR
alpha-
terpinyl 邻氨基苯甲酸 anthranilate
FL/FR
alpha-
butyl 肉桂醛 cinnamaldehyde
FL/FR
醛 aldehydic
醛 aldehydic
nonanal (aldehyde C-9)
FL/FR
茴香 anise
星 star
茴香 anise oil CO2 extract
FL/FR
aromatic
para-
cresyl isobuty率 rate
FL/FR
laevo-
紫苏醛 laevo-perillaldehydeFL/FR
FL/FR
香醋 balsamic
安息香 benzoin 精华/精粹/精萃 absolute 替代者 replacer
FL/FR
没药 myrrh oil CO2 extract
FL/FR
代没药 opoponax 精华/精粹/精萃 absolute (balsamodendron balsamodendron 卡法尔 kafal)
FL/FR
香草醛烯 vanillylidene acetone
FL/FR
citrus
citronellyl oxyacetaldehyde
FL/FR
(Z)-4-
decenal
FL/FR
laevo-
linalool
FL/FR
linalool
FL/FR
floral
bois de rose oil brazil
FL/FR
dihydrolinalool
FL/FR
芳樟基 linalyl 邻氨基苯甲酸 anthranilate
FL/FR
穆格 muguet carbinol
FL/FR
穆格 muguet shiseol
FL/FR
tetrahydrolinalool
FL/FR
依兰 ylang 依兰 ylang 花 flower oil
FL/FR
依兰 ylang 依兰 ylang 花 flower oil CO2 extract
FL/FR
依兰 ylang 依兰 ylang 花 flower oil I
FL/FR
依兰 ylang 依兰 ylang 花 flower oil II
FL/FR
依兰 ylang 依兰 ylang 花 flower oil III
FL/FR
果味的 fruity
芳樟基 linalyl benzoate
FL/FR
芳樟基 linalyl cinnamate
FL/FR
苦 bitter
orange peel oil brazil
FL/FR
green
芹菜 celery ketone
FL/FR
cyclohexyl ethyl alcohol
FL/FR
linalool oxide
FL/FR
草药 HERBAL
芹菜 apium graveolens 种子 seed oil
FL/FR
cardamom 馏出物 distillates
FL
野生 wild
胡萝卜 carrot 种子 seed oil terpeneless
FL/FR
芹菜 celery flavor
FL
芹菜 celery 种子 seed oil 馏出物 distillates
FL
3,6-
dimethyl-3-octanol
FL/FR
薰衣草 lavender oil
FL/FR
芳樟基 linalyl propionate
FL/FR
瓜 melon
羟柠檬醛 hydroxycitronellal diethyl acetal
FL/FR
酚醛的 phenolic
para-
cresyl phenyl acetate
FL/FR
粉状的 powdery
hydroxycitronellol
FL/FR
溶剂 solvent
methyl phenyl sulfide
FL
spicy
多香果粉 allspice berry 精华/精粹/精萃 absolute
FL/FR
cardamom 种子 seed oil CO2 extract
FL/FR
肉桂 cinnamon 皮 bark 精华/精粹/精萃 absolute
FL/FR
肉桂 cinnamon 皮 bark oil (肉桂 cinnamomum zeylanicum) india
FL/FR
肉桂 cinnamon 皮 bark oil ceylon
FL/FR
肉桂 cinnamon leaf oil ceylon
FL/FR
丁香 clove 芽 bud 精华/精粹/精萃 absolute
FL/FR
丁香 clove 芽 bud oil
FL/FR
丁香 clove flavor
FL
丁香 clove leaf oil
FL/FR
丁香 clove stem oil
FL/FR
荜澄茄/山苍子 cubeb oil
FL/FR
mace flavor
FL
mace oil
FL/FR
肉豆蔻 坚果 nutmeg oleoresin
FL/FR
胡椒 pepper 树 tree berry oil
FL/FR
waxy
羟柠檬醛 hydroxycitronellal
FL/FR
羟柠檬醛 hydroxycitronellal dimethyl acetal
FL/FR
woody
金钟柏 thuja occidentalis leaf oil
FL/FR
 
潜在用途 Potential Uses:
FR佛手柑 bergamot
FL/FR香芹籽 ca生的 raway 种子 seed
FRcardamom oil 替代者 replacer
FRcranberry
FRcumin oil 替代者 replacer
FR姜草 gingergrass
FRhop
FRhuckleberry
FRlavandin
FRroot 啤酒 beer
FR薄荷 peppermint
FR香草 FRvanilla
 
存在(自然 Occurrence (nature, food, 其他) other):note
 砂质睾丸马来西亚果油@ 1.70% amomum testaceum ridl. fruit oil malaysia @ 1.70%
Data gc GC 搜索 Search Trop Picture
 当归根油@ 0.10% angelica root oil @ 0.10%
Data gc GC 搜索 Search Trop Picture
 月桂叶 bay laurel leaf
搜索 Search Trop Picture
 佛手柑植物野生 bergamot plant wild
搜索 Search Trop Picture
 香菜油 caraway oil
搜索 Search Trop Picture
 香菜植物 caraway plant
搜索 Search Trop Picture
 香菜籽油@ 0.10% caraway seed oil @ 0.10%
Data gc GC 搜索 Search Trop Picture
 洋甘菊甜假洋甘菊植物 chamomile sweet false chamomile plant
搜索 Search Trop Picture
 姜根茎 ginger rhizome
搜索 Search Trop Picture
 姜草 gingergrass
搜索 Search Trop Picture
 lavandin
搜索 Search pmc PMC Picture
 乌拉圭香橙油@ 0.02-0.03% mandarin oil uruguay @ 0.02-0.03%
Data gc GC 搜索 Search Trop Picture
 橙皮油苦味瓷@ 0.01% orange peel oil bitter china @ 0.01%
Data gc GC 搜索 Search Trop Picture
 perilla
搜索 Search Trop Picture
 玫瑰油奥托保加利亚@ 0.05% rose oil otto bulgaria @ 0.05%
Data gc GC 搜索 Search Trop Picture
 萨文 savin
搜索 Search Trop Picture
 咸味冬季咸味植物 savory winter savory plant
搜索 Search Trop Picture
 留兰香叶 spearmint leaf
搜索 Search Trop Picture
 留兰香油 spearmint oil
搜索 Search Trop Picture
 姜黄根油加水蒸馏@ 0.17% turmeric root oil hydrodistilled @ 0.17%
Data gc GC 搜索 Search Trop Picture
 虫子油西班牙@ 0.15% wormseed oil spain @ 0.15%
Data gc GC 搜索 Search Trop Picture
 
同义词 Synonyms:
 环己-1-烯-1-甲醇 cyclohex-1-ene-1-methanol, 4-(1-methylethenyl)-
1-cyclohexene-1-甲醇 methanol, 4-(1-methylethenyl)
 二氢枯基异丙醇 dihydro cuminyl alcohol
 hydrocumin alcohol
1-hydroxymethyl-4-isopropenyl-1-cyclohexene
p-mentha-1,8-dien-7-ol
para-mentha-1,8-dien-7-ol
 menthadien-7-carbinol
1,8-p-menthadien-7-ol
4-(1-methyl ethenyl)-1-cyclohexene-1-甲醇 methanol
[4-(1-methylethenyl)-1-cyclohexen-1-yl]甲醇 methanol
4-(1-methylethenyl)-1-cyclohexene-1-甲醇 methanol
 紫苏的 perillic alcohol
 紫苏醇 perillol
(4-prop-1-en-2-yl-1-cyclohexenyl)甲醇 methanol
[4-(prop-1-en-2-yl)cyclohex-1-en-1-yl]甲醇 methanol
4-isopropenyl cyclohex-1-en-1-yl 甲醇 methanol
4-isopropenyl 环己-1-烯-1-甲醇 cyclohex-1-ene-1-methanol
4-isopropenyl cyclohex-1-enyl 甲醇 methanol
(4-isopropenyl-1-cyclohexen-1-yl)甲醇 methanol
4-isopropenyl-1-cyclohexene carbinol
4-isopropenyl-1-cyclohexenecarbinol
4-isopropenyl-1-cyclohexenyl 甲醇 methanol
4-isopropenyl-环己-1-烯-1-甲醇 cyclohex-1-ene-1-methanol
4-isopropenyl-cyclohex-1-enyl甲醇 methanol
4-isopropenylcyclohex-1-en-1-yl甲醇 methanol
4-isopropenylcyclohex-1-enyl 甲醇 methanol
4-isopropenylcyclohex-1-enyl甲醇 methanol
 

文章 Articles:

美国专利 US Patents:3,993,604-脂环族化合物 604 - Alicyclic compounds, 它们的用途和制备方法 their use and process for preparing same
已发布 PubMed:氨基修饰的紫苏醇衍生物的合成和抗增殖作用。 Synthesis and antiproliferative effects of amino-modified perillyl alcohol derivatives.
已发布 PubMed:揭示与山松甲虫相关病原体罗汉果的柠檬烯修饰或利用有关的酶的基因发现。 Gene discovery for enzymes involved in limonene modification or utilization by the mountain pine beetle-associated pathogen Grosmannia clavigera.
已发布 PubMed:条件对黑曲霉生物转化(+)-柠檬烯的影响 Influence of culture conditions on the biotransformation of (+)-limonene by Aspergillus niger.
已发布 PubMed:一种新型替莫唑胺-紫苏醇共轭物在体外和体内颅内三阴性肿瘤生长中均表现出对乳腺癌细胞的优异活性。 A Novel Temozolomide-Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells In Vitro and Intracranial Triple-Negative Tumor Growth In Vivo.
已发布 PubMed:鼻内吸入治疗中枢橙花系统肿瘤的系统评价 A systematic review of inhaled intranasal therapy for central nervous system neoplasms: 一种新兴的治疗选择。 an emerging therapeutic option.
已发布 PubMed:紫苏醇吸入治疗复发性恶性橙花胶质瘤患者的长期预后。 Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation.
已发布 PubMed:紫苏醇抑制肺中抗原诱导的免疫反应。 Perillyl alcohol suppresses antigen-induced immune responses in the lung.
已发布 PubMed:在肯尼亚不同地理位置繁殖的新康乃馨香精油的化学成分和驱蚊性 Chemical composition and mosquito repellency of essential oil of Conyza newii propagated in different geographical locations of Kenya.
已发布 PubMed:鼻内注射紫苏醇可在体内激活外周和与支气管相关的免疫系统。 Intranasal administration of perillyl alcohol activates peripheral and bronchus-associated immune system in vivo.
已发布 PubMed:使用紫苏醇和新型嵌合血清型癌症终结者 进行的胰腺癌化学预防基因治疗(cgt)。 Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus.
已发布 PubMed:d-柠檬烯和紫苏醇在鼠模型中的皮肤修复特性。 Skin repair properties of d-Limonene and perillyl alcohol in murine models.
已发布 PubMed:d-柠檬烯及其代谢产物紫苏醇的抗应激作用。 Anti-stress effects of d-limonene and its metabolite perillyl alcohol.
已发布 PubMed:gstm1和gstt1基因多态性对以紫苏醇为基础的恶性橙花胶质瘤患者生存率的影响。 Influence of GSTM1 and GSTT1 polymorphisms on the survival rate of patients with malignant glioma under perillyl alcohol-based therapy.
已发布 PubMed:eif4e过表达赋予了紫苏醇和雷帕霉素介导的端粒酶逆转录酶调节作用。 eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase.
已发布 PubMed:大肠杆菌的代谢工程,用于柠檬烯和紫苏醇的生产。 Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production.
已发布 PubMed:紫苏醇作为抗调节剂,可通过改善氧化损伤和细胞增殖来抵抗大鼠肝癌的发生。 Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation.
已发布 PubMed:环状芳族磺酰胺的双重还原 Double reduction of cyclic aromatic sulfonamides: (+)-半膜和(+)-半膜醇的合成。 synthesis of (+)-mesembrine and (+)-mesembranol.
已发布 PubMed: 4-溴-2-(哌啶-1-基)噻唑-5-基-苯基甲酮(12b)抑制癌细胞中的na + / k(+)-atpase和拉斯 ras癌基因活性。
已发布 PubMed:植物化学紫苏醇和雷帕霉素对htert-mtor-raptor蛋白复合物的破坏。 Disruption of an hTERT-mTOR-RAPTOR protein complex by a phytochemical perillyl alcohol and rapamycin.
已发布 PubMed:基于全细胞的cyp153a6催化的(s)-柠檬烯羟基化效率取决于宿主背景和通过醇吸收单萜的收益。 Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.
已发布 PubMed:紫苏醇通过诱导p15(ink4b)和p21(waf1 / cip1)导致g1阻滞。 Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction.
已发布 PubMed:紫苏醇用于治疗耐替莫唑胺的橙花胶质瘤。 Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
已发布 PubMed:异戊二烯紫苏醇可抑制前列腺癌细胞的端粒酶活性。 The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
已发布 PubMed:饮食中的异戊二烯衍生物化学预防肝癌的发生 Chemoprevention of hepatocarcinogenesis with dietary isoprenic derivatives: 细胞和分子方面。 cellular and molecular aspects.
已发布 PubMed:pa药根蒸气馏出物成分和结构相关化合物对 肠道细菌的生长抑制作用。 Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.
已发布 PubMed:用基于紫苏醇的疗法治疗的巴西橙花胶质瘤患者的egf + 61a> g多态性和egf血清水平的分析。 Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.
已发布 PubMed: 镰刀菌属异孢霉对微生物微生物羟基化的s- S-(-)-紫苏醇
已发布 PubMed:钙阻断剂通过操纵组织转谷氨酰胺酶活性来降低套细胞淋巴瘤的硼替佐米耐药性。 Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities.
已发布 PubMed:香叶小球藻在厌氧单萜降解中诱导的香叶醇和香叶醛脱氢酶。 Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.
已发布 PubMed:含紫苏醇的plga微粒的抗癌功效。 Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.
已发布 PubMed:紫苏叶中活性成分对脂质膜的影响 Influence of the active compounds of Perilla frutescens leaves on lipid membranes.
已发布 PubMed:非黑素瘤皮肤癌的化学预防。 Nonmelanoma skin cancer chemoprevention.
已发布 PubMed:选择性生物氧化催化剂的有效途径 An efficient route to selective bio-oxidation catalysts: 包含建模的迭代方法 an iterative approach comprising modeling, 多样化 diversification, 和筛选 and screening, 基于cyp102a1。 based on CYP102A1.
已发布 PubMed:细胞生理而不是酶动力学可以决定细胞色素p450催化c-h-氧官能化的效率。 Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
已发布 PubMed:评估生物风味剂的抗氧化剂和抗增殖能力。 Evaluation of the antioxidant and antiproliferative potential of bioflavors.
已发布 PubMed:异戊二烯化抑制剂预防移植冠状动脉疾病。 Prevention of transplant coronary artery disease by prenylation inhibitors.
已发布 PubMed:汀类药物引起的大鼠骨骼肌纤维收缩功能异常的机制。 Mechanism of statin-induced contractile dysfunction in rat cultured skeletal myofibers.
已发布 PubMed: 紫苏醇可防止乙醇通过抑制氧化应激诱导的威士达 Wi星 star大鼠急性肝损伤 , nfκ-b激活和促炎细胞因子的产生。 NFκ-B activation and proinflammatory cytokine production.
已发布 PubMed:胶质母细胞瘤细胞(a172)对紫苏醇的化学抗性蛋白表达模式。 Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.
已发布 PubMed:非手术疗法在非黑素瘤皮肤癌治疗中的创新。 Nonsurgical innovations in the treatment of nonmelanoma skin cancer.
已发布 PubMed:抗癌药紫苏醇是na / k-atpase抑制剂。 The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.
已发布 PubMed:萜烯紫苏醇对复发性胶质母细胞瘤患者生存率的疗效 Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.
已发布 PubMed:潜在新型凋亡剂的设计与合成 Design and Synthesis of Potential New Apoptosis Agents: 含有紫苏醇和新的约束类视黄醇的杂化化合物。 Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids.
已发布 PubMed:天然产物有望阻止皮肤癌变的早期事件。 The promise of natural products for blocking early events in skin carcinogenesis.
已发布 PubMed:局部用紫苏醇乳膏化学预防皮肤癌的2a期研究。 A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.
已发布 PubMed:暴露于紫苏醇的胶质母细胞瘤细胞(a172)的动态蛋白质组学概述。 Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol.
已发布 PubMed:(1s (1S,2R,4s)-1-[[(苄基氨基)-甲基] -4-(丙-1-烯-2-基)环己烷-1 4S)-1-[(Benzyl-amino)-meth-yl]-4-(prop-1-en-2-yl)cyclo-hexane-1,2-二醇。 2-diol.
已发布 PubMed:光化性角化病的药物治疗。 Pharmacotherapy of actinic keratosis.
已发布 PubMed:黄连木变色乳香油对刘易斯肺癌实验性生长的保护作用。 Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma.
已发布 PubMed:紫苏醇和茉莉酸甲酯使癌细胞对顺铂敏感。 Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin.
已发布 PubMed:细胞色素p450cam的三顺反子过表达 Tricistronic overexpression of cytochrome P450cam, 普达氧还蛋白 putidaredoxin, 普达氧还蛋白还原酶提供了有用的基于细胞的催化系统。 and putidaredoxin reductase provides a useful cell-based catalytic system.
已发布 PubMed:β-糖苷酶和半胱氨酸蛋白酶在结肠癌细胞中新型糖缀合物的细胞毒性中的可能贡献。 Possible contribution of beta-glycosidases and caspases in the cytotoxicity of novel glycoconjugates in colon cancer cells.
已发布 PubMed:[化学预防食道鳞状细胞瘤的天然化合物-实验研究]。 [Natural compounds in chemoprevention of esophageal squamous cell tumors--experimental studies].
已发布 PubMed:柠檬精油的成分可减轻东pol碱引起的痴呆。 Components of lemon essential oil attenuate dementia induced by scopolamine.
已发布 PubMed:去探险家 GO Explorer: 一种基因本体论工具,可帮助解释shot弹枪蛋白质组学数据。 A gene-ontology tool to aid in the interpretation of shotgun proteomics data.
已发布 PubMed:抗凝血酶作为复发性胶质母细胞瘤多形性患者接受紫苏醇治疗的预后生物标志物。 Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol.
已发布 PubMed: 紫苏醇可减弱拉斯 ras-erk信号传导,从而抑制小鼠皮肤发炎和肿瘤发生。
已发布 PubMed:复发性恶性橙花胶质瘤的肿瘤形态学和肿瘤周围水肿与鼻内注射紫苏醇的治疗反应的相关性。 Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol.
已发布 PubMed:临床试验的门户。 Gateways to clinical trials.
已发布 PubMed:紫苏醇静脉内亚微米乳剂的高效液相色谱和药代动力学分析。 High-performance liquid chromatographic and pharmacokinetic analyses of an intravenous submicron emulsion of perillyl alcohol in rats.
已发布 PubMed:同时定量测定10个金盏花品种花中的8种三萜类单酯。新型三萜类单酯的合成和表征 Sensitive determination of monoterpene alcohols in urine by HPLC-FLD combined with ESI-MS detection after online-solid phase extraction of the monoterpene-coumarincarbamate derivates.
已发布 PubMed:黑素瘤分化相关基因7 / interleukin-24和紫苏醇抑制体外胰腺癌细胞生长的机理。 Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.
已发布 PubMed: 胶质瘤中的拉斯 ras途径激活 : 鼻内注射紫苏醇的战略目标。 a strategic target for intranasal administration of perillyl alcohol.
已发布 PubMed:紫苏醇化学预防结合 基因治疗可减少胰腺癌的发病机理。 Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.
已发布 PubMed:p-mentha-1上的芳香剂评论 Fragrance material review on p-mentha-1,8-dien-7-ol。 8-dien-7-ol.
已发布 PubMed:萜类支架糖基化的新生物催化剂的发现。 Discovery of new biocatalysts for the glycosylation of terpenoid scaffolds.
已发布 PubMed:磷脂酶d催化磷脂酰化单萜醇的合成及其对 癌细胞的抗增殖作用 Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
已发布 PubMed:联苯烷基乙酰基氢醌醚抑制鼠b16黑素瘤细胞的增殖。 Biphenylalkylacetylhydroquinone ethers suppress the proliferation of murine B16 melanoma cells.
已发布 PubMed:紫苏醇在胰腺癌中的初步研究。 A pilot study of perillyl alcohol in pancreatic cancer.
已发布 PubMed:在地幔细胞淋巴瘤中对硼替佐米耐药的本构性nf-kappab活性的患病率 Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma.
已发布 PubMed:局部用紫苏醇乳膏化学预防皮肤癌的1期研究。 Phase 1 study of topical perillyl alcohol cream for chemoprevention of skin cancer.
已发布 PubMed:抗炎衰老活性物质5203-1分子可促进健康衰老和延长寿命。 Anti-inflammatory senescence actives 5203-L molecule to promote healthy aging and prolongation of lifespan.
已发布 PubMed:来自成 恶性橙花胶质瘤复发患者鼻腔注射紫苏醇的第i / ii期研究的初步结果。 Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
已发布 PubMed:紫苏醇可防止fe-nta诱导的肾毒性和大鼠实验模型中的早期肿瘤促进事件。 Perillyl Alcohol Protects Against Fe-NTA-Induced Nephrotoxicity and Early Tumor Promotional Events in Rat Experimental Model.
已发布 PubMed:克隆来自考氏肠杆菌6l的柠檬烯羟基化的四个基因。 Cloning of four genes involved in limonene hydroxylation from Enterobacter cowanii 6L.
已发布 PubMed:紫苏醇和紫苏酸诱导非小细胞肺癌细胞的细胞周期停滞和凋亡。 Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
已发布 PubMed:每日口服紫苏醇(nsc 641066)在难治性转移性乳腺癌中的二期试验。 Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer.
已发布 PubMed:rab-small gtpases参与氟伐他汀和普伐他汀诱导的大鼠骨骼肌纤维的空泡化。 Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers.
已发布 PubMed:紫苏醇和染料木黄酮可差异调节 类肿瘤细胞中的pkb / akt和4e-bp1磷酸化以及eif4e / eif4g相互作用。 Perillyl alcohol and genistein differentially regulate PKB/Akt and 4E-BP1 phosphorylation as well as eIF4E/eIF4G interactions in human tumor cells.
已发布 PubMed:间变性少突胶质瘤对鼻腔注射紫苏醇反应良好 Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: 病例报告和文献复习。 a case report and literature review.
已发布 PubMed:异戊二烯类紫苏醇抑制细胞周期 Cell cycle arrest by the isoprenoids perillyl alcohol, 香叶醇 geraniol, 法尼醇在 胰腺腺癌细胞中由p21(cip1)和p27(kip1)介导。 and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
已发布 PubMed:醇和热休克处理对 肺腺癌细胞a549基因表达的影响 Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549.
已发布 PubMed:己酮可可碱致敏的紫苏醇体外诱导u937细胞凋亡 In vitro induction of apoptosis in U937 cells by perillyl alcohol with sensitization by pentoxifylline: 增加bcl-2和bax蛋白表达。 increased BCL-2 and BAX protein expression.
已发布 PubMed: 黄连木变种的乳香油。 chia chia抑制 k562白血病细胞的生长和存活并减弱血管生成。
已发布 PubMed:柑桔冷榨果皮油的特征香气成分的评价 Evaluation of characteristic aroma compounds of Citrus natsudaidai Hayata (Natsudaidai) cold-pressed peel oil.
已发布 PubMed:萜类作为植物抗氧化剂。 Terpenoids as plant antioxidants.
已发布 PubMed:紫苏醇在bcr / abl转化的白血病细胞中诱导c-myc依赖性凋亡。 Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
已发布 PubMed:恶性橙花胶质瘤的分子遗传学的最新进展公开了抗肿瘤药紫苏醇的靶标。 Recent advances in the molecular genetics of malignant gliomas disclose targets for antitumor agent perillyl alcohol.
已发布 PubMed:紫苏醇在mcf-7细胞中抑制了多环芳烃诱导的cyp1b1活性。 Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells.
已发布 PubMed:紫苏醇抑制钙依赖性组成性核因子-κB途径。 Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.
已发布 PubMed:临床试验的门户。 Gateways to clinical trials.
已发布 PubMed:利莫尼的区域和立体选择性真菌氧官能化。 Regio- and stereoselective fungal oxyfunctionalisation of limonenes.
已发布 PubMed:紫苏醇抑制 前列腺癌细胞中雄激素受体的表达和功能 Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells.
已发布 PubMed:法呢基转移酶的蛋白和m-rna表达 Protein and m-RNA expression of farnesyl-transferases, 大鼠肝肝细胞中的rhoa和rhob RhoA and RhoB in rat liver hepatocytes: 紫苏醇和维生素A在体内的作用。 action of perillyl alcohol and vitamin A in vivo.
已发布 PubMed:caax-异戊二烯基转移酶对于长春花玫瑰细胞中涉及单萜生物合成途径早期基因的表达至关重要。 CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.
已发布 PubMed:一些非洲植物精油对冈比亚按蚊的熏蒸毒性。 Fumigant toxicity of the essential oils of some African plants against Anopheles gambiae sensu stricto.
已发布 PubMed:新型分枝杆菌从柠檬烯生物催化生产紫苏醇。在恶臭假单胞菌中表达的细胞色素p450烷烃羟化酶。 Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida.
已发布 PubMed:紫苏醇可诱导 成胶质细胞瘤多形细胞凋亡。 Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells.
已发布 PubMed:防癌作用选择饮食因素。 Cancer preventive role of selected dietary factors.
已发布 PubMed:-柠檬烯对balb / c小鼠淋巴瘤免疫反应的影响 Effect of D-limonene on immune response in BALB/c mice with lymphoma.
已发布 PubMed:一种用于定量局部用药膏配方中紫苏醇的hplc方法。 An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation.
已发布 PubMed:新型精神营养真菌 A novel psychrotrophic fungus, 小孢子菌 Mortierella minutissima, 用于d-柠檬烯的生物转化。 for D-limonene biotransformation.
已发布 PubMed: sle1ab介导b淋巴细胞中stat3和拉斯 ras-erk信号通路的异常激活。
已发布 PubMed: (+)-和(-)-柠檬烯 -柠檬烯 limonenes 柠檬烯 limonenes -柠檬烯 -柠檬烯 limonenes 柠檬烯 limonenes及其代谢产物代谢中的物种差异 , 香芹酮和carveols and carvones, 色素p450酶在小鼠肝微粒体中的表达 by cytochrome P450 enzymes in liver microsomes of mice, 老鼠 rats, 豚鼠 guinea pigs, 兔子 rabbits, 小狗 dogs, 猴子 monkeys, 和 类。 and humans.
已发布 PubMed:预防癌症的临床试验 Clinical trials in cancer prevention: 当前的结果和对未来的展望。 current results and perspectives for the future.
已发布 PubMed:紫苏醇在乳腺肿瘤中的替代替代终点生物标志物试验。 A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia.
已发布 PubMed:r-(+)-紫苏醇诱导的细胞周期变化 R-(+)-perillyl alcohol-induced cell cycle changes, 肌动蛋明串球菌骨架改变 altered actin cytoskeleton, 并降低结肠癌sw480细胞中的拉斯 ras和p34(cdc2)表达。
已发布 PubMed:单萜增强了头颈癌细胞对体外放射治疗的敏感性。 Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.
已发布 PubMed:肯尼亚一些植物的精油对冈比亚按蚊的驱避性。 Repellency of essential oils of some Kenyan plants against Anopheles gambiae.
已发布 PubMed:类异戊二烯介导的甲羟戊酸酯合成抑制作用的研究,用于癌症化学疗法和化学预防。 Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.
已发布 PubMed:紫苏醇是血管生成抑制剂。 Perillyl alcohol is an angiogenesis inhibitor.
已发布 PubMed:在28天中的14天中,每天服用四次紫苏醇的第一阶段试验。 A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.
已发布 PubMed: 与sti571联合使用对k K562细胞增殖和凋亡的影响
已发布 PubMed:德拉克头草精油在小鼠扭体试验中的抗伤害性作用。 Antinociceptive effects of the essential oil of Dracocephalum kotschyi in the mouse writhing test.
已发布 PubMed:临床试验的门户。 Gateways to clinical trials.
已发布 PubMed:将患者作为自己的对照进行i期临床试验的费用评估。 Using patients as their own controls for cost evaluation of phase I clinical trials.
已发布 PubMed:紫苏醇在体外和体内抑制 乳腺癌细胞的生长。 Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo.
已发布 PubMed:紫苏醇介导的肺癌细胞增殖抑制 Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: 其化学治疗作用的潜在机制。 potential mechanisms for its chemotherapeutic effects.
已发布 PubMed:利用云杉悬浮培养技术改造萜烯。 Transformation of terpenes using a Picea abies suspension culture.
已发布 PubMed:紫苏醇外用乳膏制剂的开发。 Development of a perillyl alcohol topical cream formulation.
已发布 PubMed:增生剂对正常和体外球囊损伤猪冠状动脉血管功能的影响。 Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.
已发布 PubMed:转移性雄激素非依赖性前列腺癌患者每天服用紫苏醇(nsc 641066)的ii期试验。 Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer.
已发布 PubMed:临床试验的门户。 Gateways to clinical trials.
已发布 PubMed: 紫苏醇对bcr / abl转化细胞的抗白血病作用以拉斯 ras和raf独立的方式间接抑制通过mek的信号传导。
已发布 PubMed:高热可增强紫苏醇对癌细胞的细胞毒性。 Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia.
已发布 PubMed:细胞毒性剂的研究表明,凋亡不是橙花母细胞瘤细胞克隆形成死亡的主要决定因素。 Studies with cytotoxic agents suggest that apoptosis is not a major determinant of clonogenic death in neuroblastoma cells.
已发布 PubMed:紫苏醇和紫苏醛诱导体外培养的broto和a549细胞的细胞周期停滞和细胞死亡。 Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro.
已发布 PubMed:紫苏醇的I期试验每天连续进行四次。 Phase I trial of perillyl alcohol administered four times daily continuously.
已发布 PubMed:皮肤癌化学预防 Skin cancer chemoprevention: 拯救皮肤的策略。 strategies to save our skin.
已发布 PubMed:紫苏醇通过增加前列腺癌细胞中fas途径介导的放射增敏作用。 Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells.
已发布 PubMed:角分辨低相干干涉法原位检测大鼠食道上皮中的肿瘤转化和化学预防作用。 In situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry.
已发布 PubMed:紫苏醇作为恶性橙花胶质瘤的放射/化学增敏剂。 Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.
已发布 PubMed:紫苏醇在转移性结直肠癌患者中的ii期试验。 Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer.
已发布 PubMed:紫苏醇作为化学预防剂在正亚硝基甲基苄胺诱导的大鼠食道肿瘤发生中的作用。 Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
已发布 PubMed:柠檬烯的细菌生物转化 Biotransformation of limonene by bacteria, 菌类 fungi, 酵母菌 yeasts, 和植物。 and plants.
已发布 PubMed:紫苏醇在晚期实体瘤患者中的第一阶段试验。 A phase I trial of perillyl alcohol in patients with advanced solid tumors.
已发布 PubMed: 单萜调节拉斯 ras和拉斯 ras相关蛋白的表达。
已发布 PubMed:基于机制的体外潜在癌症化学预防剂筛选。 Mechanism-based in vitro screening of potential cancer chemopreventive agents.
已发布 PubMed:微量元素在癌症的化学预防中。 Micronutrients in cancer chemoprevention.
已发布 PubMed:类异戊二烯紫苏醇和法呢醇对胰腺癌化学预防中凋亡生物标志物的影响 Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
已发布 PubMed:植物来源的单萜在转录后水平上抑制仓鼠肾细胞3-羟基-3-甲基戊二酰辅酶a还原酶的合成。 Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level.
已发布 PubMed:紫苏醇抑制乳腺细胞迁移而不影响细胞粘附。 Perillyl Alcohol Inhibits Breast Cell Migration without Affecting Cell Adhesion.
已发布 PubMed:紫苏醇对橙花胶质c6细胞系的体外影响以及绒毛膜尿囊膜模型的抗转移活性。 Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
已发布 PubMed:气相色谱-质谱法测定尿液中的羟基萜烯,对单萜的暴露进行灵敏的生物监测。 Sensitive biomonitoring of monoterpene exposure by gas chromatographic-mass spectrometric measurement of hydroxy terpenes in urine.
已发布 PubMed:单萜通过调节细胞周期相关的蛋白表达来抑制 结肠癌细胞的增殖。 Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
已发布 PubMed:顽固性恶性肿瘤患者紫苏醇的I期研究。 Phase I study of perillyl alcohol in patients with refractory malignancies.
已发布 PubMed:每日紫苏醇在晚期 癌患者中的II期试验 A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: 东部合作肿瘤小组研究e2e96。 Eastern Cooperative Oncology Group Study E2E96.
已发布 PubMed: 紫苏醇对tp拉斯 ras小鼠模型中黑素瘤的影响。
已发布 PubMed: cyp2c9和cyp2c19在 肝微粒体中将(+)-和(-)-柠檬烯 -柠檬烯 limonenes 柠檬烯 limonenes -柠檬烯 -柠檬烯 limonenes 柠檬烯 limonenes代谢为相应的香芹醇和紫苏醇。
已发布 PubMed:减肥药和补品 Weight-loss drugs and supplements: 还有更安全的选择吗? are there safer alternatives?
已发布 PubMed:紫苏醇(poh)的抗白血病活性 Antileukemia activity of perillyl alcohol (POH): 从g0 / g1停滞中解脱凋亡表明poh对bcr / abl转化细胞的主要作用是诱导生长停滞。 uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
已发布 PubMed:大鼠肝微粒体中(+)-和(-)-柠檬烯对映异构体代谢为香芹酚和紫苏醇衍生物的性别差异。 Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes.
已发布 PubMed:抗癌剂紫苏醇对乳腺癌细胞的抑制作用。 Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.
已发布 PubMed:恶臭假单胞菌对柠檬烯的生物转化。 Biotransformation of limonene by Pseudomonas putida.
已发布 PubMed:有前途的法呢基转移酶抑制剂的化学预防功效。 Chemopreventive efficacy of promising farnesyltransferase inhibitors.
已发布 PubMed:在早期大鼠肝癌发生过程中未能证明单萜紫苏醇对化学物质有预防作用 Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: 警告说明。 a cautionary note.
已发布 PubMed:紫苏醇(nsc 641066)在难治性实体恶性肿瘤患者中的第一阶段药代动力学试验。 Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
已发布 PubMed:pc12细胞和大鼠中抗癌药紫苏醇的细胞毒性和生物转化。 Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat.
已发布 PubMed:化学预防皮肤癌的最新技术。 The state-of-the-art in chemoprevention of skin cancer.
已发布 PubMed:嗜热脂肪芽孢杆菌br388柠檬烯羟化酶的克隆,表达及在两阶段柠檬烯转化中的应用。 Cloning and expression of the limonene hydroxylase of Bacillus stearothermophilus BR388 and utilization in two-phase limonene conversions.
已发布 PubMed:紫苏醇抑制tcr介导的[ca(2 +)](i)信号传导 Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, 改变细胞的形状和运动 alters cell shape and motility, 并诱导t淋巴细胞凋亡。 and induces apoptosis in T lymphocytes.
已发布 PubMed:烯丙基化抑制剂可治疗增生性肾脏疾病。 Prenylation inhibitors to treat proliferative renal disease.
已发布 PubMed: 表皮细胞试验的化学预防功效数据与体内数据的相关性。 Correlation of chemopreventive efficacy data from the human epidermal cell assay with in vivo data.
已发布 PubMed:化学预防的进展 Progress in cancer chemoprevention: 饮食衍生的化学预防剂的开发。 development of diet-derived chemopreventive agents.
已发布 PubMed:每天服用四次紫苏醇的第一阶段临床和药代动力学研究。 Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day.
已发布 PubMed:紫苏醇 Perillyl Alcohol, 香叶基香叶基转移酶的抑制剂 an inhibitor of geranylgeranyl transferase, 在体外诱导永生化的 血管平滑肌细胞凋亡。 induces apoptosis of immortalized human vascular smooth muscle cells in vitro.
已发布 PubMed:化学预防方面的进展。 Progress in cancer chemoprevention.
已发布 PubMed:前列腺癌的药物开发。 Drug development in prostate cancer.
已发布 PubMed:紫苏醇在bcr / abl转化的骨髓细胞系中选择性诱导g0 / g1阻滞和凋亡。 Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines.
已发布 PubMed:紫苏醇诱导乳腺癌细胞ap-1活性。 Induction of AP-1 activity by perillyl alcohol in breast cancer cells.
已发布 PubMed:竞争性3-羟基-3-甲基戊二酰辅酶A还原酶抑制不影响单萜类紫苏醇对甾醇合成的促进作用。 Enhancement of sterol synthesis by the monoterpene perillyl alcohol is unaffected by competitive 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
已发布 PubMed:气相色谱-质谱法分析血浆中的紫苏醇和代谢物。 Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma.
已发布 PubMed:红球红球菌dcl14包含柠檬烯的新型降解途径。 Rhodococcus erythropolis DCL14 contains a novel degradation pathway for limonene.
已发布 PubMed:新的柠檬烯膦酸酯和法呢基二磷酸酯类似物 Novel limonene phosphonate and farnesyl diphosphate analogues: 设计 design, 合成 synthesis, 并作为潜在的蛋白质-法呢基转移酶抑制剂进行评估。 and evaluation as potential protein-farnesyl transferase inhibitors.
已发布 PubMed:脂联蛋白原激活的ampk抑制了由营养剥夺引起的氧化性肝损伤和线粒体功能障碍,这是通过诱导法呢素x受体介导的。 Activation of the transforming growth factor beta signaling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol.
已发布 PubMed:饮食中的单萜类化合物预防和治疗癌症。 Prevention and therapy of cancer by dietary monoterpenes.
已发布 PubMed:柠檬烯代谢产物对蛋白质异戊二烯的抑制作用。 Inhibition of protein prenylation by metabolites of limonene.
已发布 PubMed:胰岛素促进香叶基香叶基转移酶的磷酸化和活化。 rab-3和rab-4的香叶基香叶基化的研究。 Insulin promotes phosphorylation and activation of geranylgeranyltransferase II. Studies with geranylgeranylation of rab-3 and rab-4.
已发布 PubMed:紫苏醇 Perillyl Alcohol: 在肿瘤学中的应用。 applications in oncology.
已发布 PubMed:单萜抑制细胞生长 Monoterpenes inhibit cell growth, 细胞周期进程 cell cycle progression, 和Cyclin d1基因在 乳腺癌细胞系中的表达。 and cyclin D1 gene expression in human breast cancer cell lines.
已发布 PubMed:原位乳腺上皮细胞中抗癌单萜对小g蛋白异戊二烯化的调节作用 Modulation of small G protein isoprenylation by anticancer monoterpenes in in situ mammary gland epithelial cells.
已发布 PubMed: 抗肿瘤药紫苏醇对胰腺细胞中h-拉斯 ras与k-拉斯 ras法呢基化和信号转导的影响
已发布 PubMed:每天服用紫苏醇的I期临床试验。 Phase I clinical trial of perillyl alcohol administered daily.
已发布 PubMed:单萜在乳腺癌的化学预防中。 Monoterpenes in breast cancer chemoprevention.
已发布 PubMed:紫苏醇对uvb诱导的鼠类皮肤癌和ap-1反式激活的抑制作用。 Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation.
已发布 PubMed:香芹酮的定量 Quantification of carvone, 桉树脑 cineole, 紫苏醛 laevo-perillaldehydeFL/FR, 用等度高效液相色谱法测定紫苏醇和丁香酚。 perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography.
已发布 PubMed:临床试验推荐资源。紫苏醇的临床试验。 Clinical trials referral resource. Clinical trials with perillyl alcohol.
已发布 PubMed:溶血磷脂酸刺激pc-3 前列腺癌细胞中的磷脂酶d活性和细胞增殖。 Lysophosphatidic acid stimulates phospholipase D activity and cell proliferation in PC-3 human prostate cancer cells.
已发布 PubMed: 膳食补充剂对 恶性细胞中拉斯 ras表达的调节
已发布 PubMed:与未转化的导管上皮细胞相比,紫苏醇诱导胰腺导管腺癌中促凋亡蛋白bak的表达。 Induction of the apoptosis-promoting protein Bak by perillyl alcohol in pancreatic ductal adenocarcinoma relative to untransformed ductal epithelial cells.
已发布 PubMed:单萜紫苏醇在nih3t3细胞中对i型和ii型香叶基香叶基蛋白转移酶的抑制作用 Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells.
已发布 PubMed:呋喃呋喃西林氟利考利的对映异构体的全合成。 Total Synthesis of the Enantiomer of the Furanocembrane Rubifolide.
已发布 PubMed:单萜对癌症的化学预防和治疗。 Cancer chemoprevention and therapy by monoterpenes.
已发布 PubMed:满四叶草精油的组成和体外抗疟活性 Composition and antimalarial activity in vitro of the essential oil of Tetradenia riparia.
已发布 PubMed:类异戊二烯在体外和体内抑制鼠b16黑素瘤的生长。 Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo.
已发布 PubMed:口服单萜疗法(紫苏醇)可减少静脉移植物的内膜增生。 Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia.
已发布 PubMed:表达热稳定的柠檬烯水合酶的大肠杆菌细胞生产α-萜品醇。 Production of alpha-terpineol from Escherichia coli cells expressing thermostable limonene hydratase.
已发布 PubMed:饮食中的类异戊二烯法尼醇和香叶醇可抑制胰腺癌的生长。 Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol.
已发布 PubMed:日粮紫苏醇化学预防结肠癌的发生。 Chemoprevention of colon carcinogenesis by dietary perillyl alcohol.
已发布 PubMed:反相高效液相色谱-紫外检测法测定血浆中的紫苏酸 Analysis of perillic acid in plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
已发布 PubMed:紫苏醇对4-(甲基亚硝胺基)-1-(3-吡啶基)-1-丁酮诱导的(c3h / hej x a / j)f1小鼠肺肿瘤的化学预防作用。 Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.
已发布 PubMed:天然存在的肿瘤抑制剂预防乳腺肿瘤前转化。 Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors.
已发布 PubMed:柠檬烯抑制4-(甲基亚硝胺基)-1-(3-吡啶基)-1-丁酮的代谢活化。 Inhibition of metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by limonene.
已发布 PubMed:单萜体外抑制肿瘤细胞生长 Inhibition of tumor cell growth by monoterpenes in vitro: 拉斯 ras独立作用机制的证据。
已发布 PubMed:化学预防乳腺癌。 Chemoprevention of breast cancer.
已发布 PubMed:临床发展计划 Clinical development plan: 紫苏醇。 l-perillyl alcohol.
已发布 PubMed:化学预防药物开发的策略和计划 Strategy and planning for chemopreventive drug development: 临床发展计划ii。 clinical development plans II.
已发布 PubMed:癌症化学预防的新药物。 New agents for cancer chemoprevention.
已发布 PubMed:单萜作为恶性细胞增殖的调节剂。 Monoterpenes as regulators of malignant cell proliferation.
已发布 PubMed:柠檬烯和紫苏醇对胰腺癌和乳腺癌的抗肿瘤作用。 Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.
已发布 PubMed:效果 影响 Effects of 单萜 单萜 mono萜烯 terpenes and 米维诺林 mevinolin on 鼠类 m尿 urine 结肠 colon 瘤 tumor CT-26 in 体外 vitro and its 肝的 hepatic "转移 metastases" in 体内 vivo.
已发布 PubMed:大肠癌的遗传和细胞变化 Genetic and cellular changes in colorectal cancer: 建议的化学预防剂目标。 proposed targets of chemopreventive agents.
已发布 PubMed:单萜紫苏醇对胰腺癌的化疗 Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol.
已发布 PubMed:单萜紫苏醇诱导橙花2a细胞分化。 Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol.
已发布 PubMed:促进细胞凋亡。 Promoting apoptosis.
已发布 PubMed: 萜和洛伐他汀对拉斯 ras加工的不同影响。
已发布 PubMed:口服紫苏醇后活性药物代谢物的药代动力学 Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, 研究性抗肿瘤药 an investigational antineoplastic agent, 给狗。 to the dog.
已发布 PubMed:原生动物贾第鞭毛虫兰比亚蛋白的异戊二烯化。 Isoprenylation of proteins in the protozoan Giardia lamblia.
已发布 PubMed:柠檬烯和紫苏醇的氧化代谢产物对蛋白质异戊二烯基转移酶的抑制作用。 The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol.
已发布 PubMed:单萜紫苏醇诱导肝肿瘤细胞凋亡。 Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol.
已发布 PubMed:单萜预防和治疗乳腺癌。 Prevention and therapy of mammary cancer by monoterpenes.
已发布 PubMed:水果和蔬菜的甲羟戊酸衍生成分对癌症的化学预防。 The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables.
已发布 PubMed:异戊二烯基单萜抑制剂与细胞增殖之间的构效关系。 Structure-activity relationships among monoterpene inhibitors of protein isoprenylation and cell proliferation.
已发布 PubMed: 单萜对大鼠肝上皮肿瘤细胞的生长抑制作用不涉及拉斯 ras质膜缔合。
已发布 PubMed:烯丙基化蛋白和淋巴细胞增殖 Prenylated proteins and lymphocyte proliferation: d-柠檬烯相关单萜的抑制作用。 inhibition by d-limonene related monoterpenes.
已发布 PubMed:单萜紫苏醇抑制泛醌和胆固醇的合成。 Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol.
已发布 PubMed:紫苏醇诱导的乳腺癌消退 Mammary carcinoma regression induced by perillyl alcohol, 柠檬烯的羟基化类似物。 a hydroxylated analog of limonene.
已发布 PubMed:[叶精油成分 [Constituents of essential oils from leaves, 茎 stems, 和紫苏果实[l。] britt]。 and fruits of Perilla frutescens (L.) Britt].
已发布 PubMed:单萜生物合成 Monoterpene biosynthesis: 薄荷(薄荷脑)酶制剂对(-)-柠檬烯羟基化的特异性 specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), 留兰香(薄荷) spearmint (Mentha spicata), 和紫苏(紫苏frutescens)叶子。 and perilla (Perilla frutescens) leaves.
已发布 PubMed:来自乙酸钙不动杆菌的苯甲醇脱氢酶和苯甲醛脱氢酶ii。底物特异性和抑制研究。 Benzyl alcohol dehydrogenase and benzaldehyde dehydrogenase II from Acinetobacter calcoaceticus. Substrate specificities and inhibition studies.
已发布 PubMed:假单胞菌代谢α-萜品醇。 Metabolism of alpha-terpineol by Pseudomonas incognita.
已发布 PubMed:关于香料原料的专着。 Monographs on fragrance raw materials.
已发布 PubMed:萜的微生物转化。十四。净化与紫苏醇脱氢酶的性质。 Microbiological transformations of terpenes. XIV. Purification & properties of perillyl alcohol dehydrogenase.
已发布 PubMed:土壤假单胞菌的紫苏醇脱氢酶。 Perillyl alcohol dehydrogenase from a soil pseudomonad.
 
笔记 Notes:
抑制香叶基香叶基转移酶。紫苏醇是从薰衣草精油中分离出来的单萜 inhibits geranylgeranyl transferase. Perillyl alcohol is a monoterpene isolated from the essential oils of lavendin, 薄荷 peppermint, 薄荷 peppermint, 樱桃 cherries, 芹菜种子 celery seeds, 和其他几种植物在动物研究中,它已经显示出可以使胰腺退化 and several other plants. In animal studies it has been shown to regress pancreatic, 乳腺 mammary, 和肝肿瘤 and liver tumors, 展示出可能作为结肠化学预防剂的应用 to exhibit possible application as a chemopreventative agent for colon, skin, 和肺癌 and lung cancer, 并作为橙花母细胞瘤的化学治疗剂 and as a chemotherapeutic agent for neuroblastoma, 以及前列腺癌和结肠癌。 and prostate and colon cancer.(PMID: 9855569)[hmdb]存在于多种香精油中 9855569) [HMDB] Occurs in a variety of essential oils, 例如薰衣草 e.g. lavender
请分享您的评论。 Please share your Comments.
电子邮件地址 Email Address: