S-allyl-laevo-cysteine
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine

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    01-18300 S-烯丙基-L-半胱氨酸 01-18300 S-ALLYL-L-CYSTEINE
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    at0500 s-烯丙基-l-半胱氨酸 AT0500 S-Allyl-L-cysteine
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    a1468 s-烯丙基-1-半胱氨酸> 98.0%(lc)(t) A1468 S-Allyl-L-cysteine >98.0%(LC)(T)
Name:(2r)-2-氨基-3-丙-2-烯基硫烷基丙酸 (2R)-2-amino-3-prop-2-enylsulfanylpropanoic acid
CAS号 CAS Number: 21593-77-1Picture of molecule3D/INCHI
FDA UNII:81R3X99M15
nikkaji网站 Nikkaji Web:J490.173H
MDL :mfcd00151975 MFCD00151975
XlogP3-AA:-2.10(est) -2.10 (est)
分子量 Molecular Weight:161.22407000
式 Formula:c6 h11 n o2 s C6 H11 N O2 S
生物活性总结 BioActivity Summary:清单 listing
核磁共振预测器 NMR Predictor:预测(适用于Chrome或Firefox) Predict (works with chrome or firefox)
类别 Category:flavoring agents
 
美国 US/欧盟 EU/ fda / jecfa / fema / Flavis / 文献 Scholar /专利 Patent :
谷歌学术 Google Scholar:搜索 Search
谷歌书 Google Books:搜索 Search
谷歌学术 Google Scholar: with word "volatile"搜索 Search
谷歌学术 Google Scholar: with word "flavor"搜索 Search
谷歌学术 Google Scholar: with word "odor"搜索 Search
调香师和调味师 Perfumer and Flavorist:搜索 Search
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jecfa食品调味料 JECFA Food Flavoring:1710 S-烯丙基-1-半胱氨酸 1710 S-allyl-L-cysteine
Flavis号码 FLAVIS Number:17.036(旧) 17.036 (Old)
dg sante食品调味料 DG SANTE Food Flavourings:17.036 S-烯丙基-1-半胱氨酸 17.036 S-allyl-L-cysteine
fema号 FEMA Number:4322 s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
自由贸易区 FDA:不再提供这七种合成调味剂的使用 No longer provide for the use of these seven synthetic flavoring substances
fda mainterm(satf) FDA Mainterm (SATF):21593-77-1 ; s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
 
物理性质 Physical Properties:
出现 Appearance:白至棕褐色粉末(est) white to tan powder (est)
化验 Assay: 95.00至100.00 95.00 to 100.00
食品化学品法典列表 Food Chemicals Codex Listed: No
比重 Specific Gravity:1.19100 @ 25.00 °C.
折光率 Refractive Index:1.54200 @ 20.00 °C.
熔点 Melting Point: 214.00 to 216.00 °C. @ 760.00 mm 汞 Hg
沸点 Boiling Point: 300.00 to 301.00 °C. @ 760.00 mm 汞 Hg
蒸汽压力 Vapor Pressure:0.001000 毫米汞柱 mm汞 Hg @ 25.00 °C.
闪点 Flash Point: 275.00 °F. tcc TCC ( 135.00 °C. )
logp(o / w) logP (o/w): 1.310
保质期 Shelf Life: 如果正确存放,则为12.00个月或更长时间。 12.00 month(s) or longer if stored properly.
存储 Storage:在密封容器中冷藏。 refrigerate in tightly sealed containers.
溶于 Soluble in:
 水 water, 略 slightly
 水 water, 3.291e + 004 mg / l @ 25°c(est) 3.291e+004 mg/L @ 25 °C (est)
 
感官特性 Organoleptic Properties:
气味类型 Odor Type: roasted
气味强度 Odor Strength:高 high ,
建议在0.10%或更少的溶液中闻到 recommend smelling in a 0.10 % solution or less
cooked roasted
气味描述 Odor Description:at 0.10 % in propylene glycol. 熟烤 cooked roasted
来自其他 的气味和/或风味描述(如果找到)。 Odor and/or flavor descriptions from others (if found).
 
化妆品信息 Cosmetic Information:
没找到 None found
 
供应商 Suppliers:
艾克辛 Axsyn
仅供实验/研究使用。 For experimental / research use only.
半胱氨酸 L-Cysteine,s-2-丙烯-1-基- S-2-propen-1-yl-
BOC Sciences
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
碳合蛋白 Carbosynth
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
常州朗高化工 Changzhou Longo Chemical
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
Endeavour Specialty Chemicals
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
特种化工产品组 Speciality Chemical Product Groups
外合成 ExtraSynthese
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-l-半胱氨酸(hplc)≥98% S-Allyl-L-cysteine (HPLC) ≥98%
Glentham Life Sciences
脱氧烯丙氨酸 L-Deoxyalliin
jalor-chem Jalor-Chem
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
Penta International
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
Robinson Brothers
s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine
https: //www.robinsonbrothers.uk/化学能力 chemistry-competences
圣克鲁斯生物技术 Santa Cruz Biotechnology
仅供实验/研究使用。 For experimental / research use only.
脱氧烯丙氨酸 L-Deoxyalliin
西格玛·奥尔德里奇 Sigma-Aldrich: 西格玛 Sigma
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-l-半胱氨酸≥98%(hplc) S-Allyl-L-cysteine ≥98% (HPLC)
TCI AMERICA
仅供实验/研究使用。 For experimental / research use only.
s-烯丙基-1-半胱氨酸> 98.0%(lc)(t) S-Allyl-L-cysteine >98.0%(LC)(T)
 
安全信息 Safety Information:
首选SDS Preferred SDS: 视图 View
 
危害识别 Hazards identification
 
物质或混合物的分类 Classification of the substance or mixture
根据29 cfr 1910(osha hcs)进行ghs分类 GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
没有找到。 None found.
ghs标签元素 GHS Label elements, 包括预防性声明 including precautionary statements
 
象形图 Pictogram
 
危险说明 Hazard statement(s)
没有找到。 None found.
防范说明 Precautionary statement(s)
没有找到。 None found.
口服/肠胃外毒性 Oral/Parenteral Toxicity:
未定 Not determined
皮肤毒性 Dermal Toxicity:
未定 Not determined
吸入毒性 Inhalation Toxicity:
未定 Not determined
 
使用安全信息 Safety in Use Information:
类别 Category:
flavoring agents
ifra纯度规格 IFRA Purity Specification: < 0.1% free allyl alcohol
s-烯丙基-laevo-半胱氨酸使用水平的推荐值 Recommendation for S-allyl-laevo-cysteine usage levels up to:
 不用于香水。 not for fragrance use.
 
最大化源自调查的每日摄入量(ms di- di- eu) : 30.00(微克/ 均/天) 30.00 (μg/capita/day)
最大化源自调查的每日摄入量(ms di- di- usa) : 2.00(微克/ 均/天) 2.00 (μg/capita/day)
修改后的理论增加的最大每日摄入量(mtamdi) Modified Theoretical Added Maximum Daily Intake (mTAMDI): nd(微克/ /天) ND (μg/person/day)
Noel(没有观察到的作用水平) NOEL (No Observed Effect Level): 250(毫克/千克体重每天) 250 (mg/kg bw per day)
关注点 Threshold of Concern:90(微克/ /天) 90 (μg/person/day)
结构类 Structure Class: iii III
采用 Use 等级 levels for FEMA GRAS flavoring 物质 substances on 哪一个 which the FEMA 专家 Expert 面板 Panel 基于 based its 判断 judgments that the 物质 substances are 通常 基因 generally 公认的 recognized as safe (GRAS).
The 专家 Expert 面板 Panel 也 also 发表 publishes 分离 separate 广泛 extensive 评论 reviews of scientific information on all FEMA GRAS flavoring 物质 substances and can be 发现 found at FEMA 味道 Flavor Ingredient 图书馆 Library
出版编号 publication number: 23
点击这里查看出版物23 Click here to view publication 23
 平均 average 通常 usual 百万分之几 ppm平均 average 最大 maximum 百万分之几 ppm
焙烤食品 baked goods: 2.0000025.00000
饮料(不含醇) beverages(nonalcoholic): --
醇饮料 beverages(alcoholic): --
早餐麦片 breakfast cereal: 2.0000025.00000
起司 cheese: 2.0000025.00000
口香糖 chewing gum: --
调味品/调味品 condiments / relishes: 2.0000025.00000
糖果烧烤 confectionery froastings: --
蛋制品 egg products: --
脂肪/油 fats / oils: 2.0000025.00000
鱼产品 fish products: 2.0000025.00000
冷冻乳制品 frozen dairy: --
水果冰 fruit ices: --
明胶/布丁 gelatins / puddings: --
砂糖 granulated sugar: --
肉汁 gravies: 2.0000025.00000
硬糖 hard candy: --
仿乳制品 imitation dairy: 2.0000025.00000
速溶咖啡/茶 instant coffee / tea: 2.0000025.00000
果酱/果冻 jams / jellies: --
肉制品 meat products: 2.0000025.00000
奶制品 milk products: --
坚果产品 nut products: 2.0000025.00000
其他谷物 other grains: --
家禽 poultry: 2.0000025.00000
加工水果 processed fruits: --
加工蔬菜 processed vegetables: 2.0000025.00000
重构蔬菜 reconstituted vegetables: 2.0000025.00000
调味料 seasonings / flavors: 2.0000025.00000
休闲食品 snack foods: 2.0000025.00000
软糖 soft candy: --
汤类 soups: 2.0000025.00000
糖替代品 sugar substitutes: --
甜酱 sweet sauces: --
 
安全参考 Safety references:
欧洲食品安全法规(efsa) European Food Safety Athority(efsa):风味使用水平;亚急性 Flavor usage levels; Subacute, 亚慢性 Subchronic, 慢性和致癌性研究;发育/ 毒性研究;遗传毒性研究... Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

欧洲食品安全局(efsa EFSA)参考 :

调味组评估91(fge.91) Flavouring Group Evaluation 91 (FGE.91): jecfa(第五十三次和第六十八次会议)评估的与脂族和脂环族单-结构相关的简单脂族和芳族硫化物和硫醇的考虑 Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di- di- , 三 tri-, and 多硫化物 poly硫化物 sulphides with or 没有 without 额外 additional 充氧 氧 oxygenated 功能性 functional groups 已评估 evaluated by by efsa EFSA in ge FGE.08Rev1 (2009)
视图 View page or 视图 View pdf

调味品组评价的科学意见91 Scientific Opinion on Flavouring Group Evaluation 91, 版本1(fge.91rev1) Revision 1 (FGE.91Rev1): jecfa(第五十三次和第六十八次会议)评估的与脂族和脂环族单-结构相关的简单脂族和芳族硫化物和硫醇的考虑 Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di- di- , 三 tri-, and 多硫化物 poly硫化物 sulphides with or 没有 without 额外 additional 充氧 氧 oxygenated 功能性 functional groups 已评估 evaluated by by efsa EFSA in ge FGE.08Rev3 (2011)
视图 View page or 视图 View pdf

调味品组评价的科学意见91 Scientific Opinion on Flavouring Group Evaluation 91, 修订2(fge.91rev2) Revision 2 (FGE.91Rev2): jecfa(第五十三次和第六十八次会议)评估的与脂族和脂环族单链结构相关的简单脂族和芳族硫化物和硫醇的考虑 Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by the JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di- di- , 三 tri-, and 多硫化物 poly硫化物 sulphides with or 没有 without 额外 additional 充氧 氧 oxygenated 功能性 functional groups 已评估 evaluated by by efsa EFSA in ge FGE.08Rev5 (2012)
视图 View page or 视图 View pdf

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德国wgk WGK Germany:3
(2r)-2-氨基-3-丙-2-烯基硫烷基丙酸 (2R)-2-amino-3-prop-2-enylsulfanylpropanoic acid
chemidplus Chemidplus:0021593771
技术 RTECS:适用于CAS#21593-77-1的ha2466200 HA2466200 for cas# 21593-77-1
 
参考资料 References:
 (2r)-2-氨基-3-丙-2-烯基硫烷基丙酸 (2R)-2-amino-3-prop-2-enylsulfanylpropanoic acid
NIST化学网络书籍 NIST Chemistry WebBook: 搜索INCHI
pubchem(cid) Pubchem (cid):9793905
pubchem(cas) Pubchem (cas):21593-77-1
 
其他资料 Other Information:
(iupac) (IUPAC):元素的原子量2009 Atomic Weights of the Elements 2009
(iupac) (IUPAC):元素的原子量2009(pdf) Atomic Weights of the Elements 2009 (pdf)
影片 Videos:元素周期表 The Periodic Table of Videos
RBC :本网站使用的原子量 Atomic Weights use for this web site
(iupac) (IUPAC):元素周期表 Periodic Table of the Elements
食品中添加的fda物质(以前为af) FDA Substances Added to Food (formerly EAFUS):视图 View
CHEBI:视图 View
CHEMBL:视图 View
KEGG (GenomeNet):C16759
hmdb(人类代谢组数据库) HMDB (The Human Metabolome Database):HMDB34323
食物 FooDB:FDB012675
出口关税代码 Export Tariff Code:2930.90.9190
vcf在线 VCF-Online:食品中的挥发性有机化合物 VCF Volatile Compounds in Food
化学蜘蛛 ChemSpider:视图 View
维基百科 Wikipedia:视图 View
rsc学习化学 RSC Learn Chemistry:视图 View
 
潜在搅拌机 Potential Blenders and core 组件 components note
气味 For Odor
胶质的 alliaceous
大蒜 Allium sativum L.oil china
FL/FR
俗气的 cheesy
S-(
methyl thio) butyrate
FL/FR
柑橘类 citrus
葡萄柚 grape果 fruit mercaptan
FL/FR
香豆素 coumarinic
通卡 tonka bean oleoresin
FR
辣的 spicy
ethyl vinyl ketone
FL/FR
含硫的 sulfurous
ferula assa-foetida assa-foetida absolute
FL/FR
methyl 3-(methyl thio) propionate
FL/FR
2-
methyl 5-(methyl thio) furan
FL/FR
methyl mercaptan
FL/FR
3-(
methyl thio) hexanol
FL/FR
用于调味 For Flavor
找不到适合这些的口味组 No flavor group found for these
allyl methyl disulfide
FL
allyl methyl trisulfide
FL
allyl propyl disulfide
FL
allyl propyl sulfide
FL
allyl propyl trisulfide
FL
diethyl trisulfide
FL
3,6-
diethyl-1,2,4,5-四噻吩和3 5-tetrathiane and 3,5-二乙基-1 5-diethyl-1,2,4-tri硫醇 thiolane 混合物 mixture 1% in 蔬菜 vegetableoil triglyceri
FL
二异丙基 diisopropyl sulfide
FL
二异丙基 diisopropyl trisulfide
FL
dimethyl tetrasulfide
FL
dipropyl sulfide
FL
ethyl isothiocyanate
FL
ethyl methyl trisulfide
FL
ethyl propyl disulfide
FL
ethyl propyl trisulfide
FL
3-(
ethyl thio) butanol
FL
(Z+E)-5-
ethyl-4-methyl-2-(2-butyl) thiazoline
FL
(Z+E)-5-
ethyl-4-methyl-2-(2-methyl propyl) thiazoline
FL
4-(
methyl thio) butanol
FL
1-
phenyl-3(5)-丙基 -propyl pyrazole
FL
3-iso
propenyl pentane 二元的 dioic acid
FL
thiophene
FL
5-
acetyl-2,3-dihydro-1,4-thiazine
FL
(±)-3-(
methyl thio) heptanal
FL
3-(
methyl thio) methyl thiophene
FL
2-
methyl-1-methyl thio-2-butene
FL
(1 pyrrolidino-(1,2E)-4H-2,4-dimethyl-1,3,5-dithiazine
FL
胶质的 alliaceous
胶质的 alliaceous
allyl disulfide
FL
allyl mercaptan
FL
allyl thiopropionate
FL
benzyl mercaptan
FL
1,3-
butane di硫醇 thiol
FL
环戊基 cyclopentyl mercaptan
FL
diethyl disulfide
FL
dipropyl trisulfide
FL
大蒜 Allium sativum L.oil china
FL/FR
2-
methyl thioacetaldehyde
FL
3-
tetrahydrothiophenone
FL
松露 truffle sulfide
FL
柑橘类 citrus
葡萄柚 grape果 fruit mercaptan
FL/FR
脂肪的 fatty
dimethyl 亚砜 sulfoxide
FL
大蒜 Allium sativum L.
allyl methyl sulfide
FL
大蒜 Allium sativum L. oleoresin
FL
多肉的 meaty
(r (R,S)-2-
mercapto-3-butanol
FL
phenyl mercaptan
FL
propyl 2-mercaptopropionate
FL
ortho-
thiocresol
FL
金属的 metallic
3-(
methyl thio) hexanol
FL/FR
发霉的 musty
2-
methyl 5-(methyl thio) furan
FL/FR
S-(
methyl thio) butyrate
FL/FR
坚果 nutty
2-
butyl-2-butenal
FL
洋葱 onion
methyl propyl disulfide
FL
methyl propyl trisulfide
FL
propyl thioacetate
FL
roasted
ethyl 3-(furfuryl thio) propionate
FL
hexyl mercaptan
FL
lactoyl 乙醇胺 ethanolamine
FL
lactoyl 乙醇胺 ethanolamine phosphate
FL
海鲜 seafood
1,4-
dithiane
FL
辣的 spicy
ethyl vinyl ketone
FL/FR
含硫的 sulfurous
allyl sulfide
FL
butyl mercaptan
FL
二烯丙基 diallyl poly硫化物 sulfides
FL
二烯丙基 diallyl tetrasulfide
FL
二烯丙基 diallyl trisulfide
FL
ethyl methyl sulfide
FL
S-
ethyl thioacetate
FL
ferula assa-foetida assa-foetida absolute
FL/FR
furfuryl methyl sulfide
FL
furfuryl thiopropionate
FL
methyl mercaptan
FL/FR
1-(
methyl thio)-2-butanone
FL
2,4,6-
trithiaheptane 10% in triacetin
FL
蔬菜 vegetable
methyl 3-(methyl thio) propionate
FL/FR
 
潜在用途 Potential Uses:
FL大蒜 Allium sativum L.
FL洋葱 onion
FLroasted
 
存在(自然 Occurrence (nature, food, 其他) other):note
 大蒜 Allium sativum L.
搜索 Search Trop Picture
 大蒜鳞茎 garlic bulb
搜索 Search Trop Picture
 洋葱鳞茎 onion bulb
搜索 Search Trop Picture
 
同义词 Synonyms:
S-allyl cysteine
S-allyl 半胱氨酸 L-cysteine
 allyl laevo-cysteine
(2R)-3-(allyl thio)-2-氨基 aminopropanoic acid
S-allyl-1-半胱氨酸 yl-l-半胱氨酸 -半胱氨酸 L-cysteine
S-allylcysteine
(2R)-2-氨基 amino-3-(prop-2-en-1-yl 硫烷基 sulfanyl) propanoic acid
(2R)-2-氨基 amino-3-prop-2-enyl硫烷基 sulfanylpropanoic acid
 cysteine, s-2-丙烯-1-基- S-2-propen-1-yl-
L-cysteine,s-2-丙烯-1-基- S-2-propen-1-yl-
L-deoxyalliin
S-prop-2-en-1-ylcysteine
S-2-propenyl-1-半胱氨酸 yl-l-半胱氨酸 -半胱氨酸 L-cysteine
S-2-propenyl-laevo-cysteine
 

文章 Articles:

已发布 PubMed:大鼠口服(s)-烯丙基-1-半胱氨酸和大蒜提取物 Oral Administration of (S)-Allyl-l-Cysteine and Aged Garlic Extract to Rats: 代谢物的测定及其药代动力学。 Determination of Metabolites and Their Pharmacokinetics.
已发布 PubMed:大蒜植物化合物对结直肠癌细胞的egfr基因调控,特别着重于s-烯丙基-1-半胱氨酸亚砜。 EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide.
已发布 PubMed:蒜氨酸热分解动力学和热降解化合物。 Thermolysis kinetics and thermal degradation compounds of alliin.
已发布 PubMed:烯丙基-1-半胱氨酸效果的评估 Evaluation of the Effects of S-Allyl-L-cysteine, s-甲基-1-半胱氨酸 S-Methyl-L-cysteine, 反式-1-丙烯基-1-半胱氨酸 trans-S-1-Propenyl-L-cysteine, 以及它们的n-乙酰化和s-氧化代谢产物对 类cyp活性的影响。 and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities.
已发布 PubMed:大蒜素通过抑制nox1清除活性氧,从而减轻了Rankl诱导的破骨细胞生成。 Alliin Attenuated RANKL-Induced Osteoclastogenesis by Scavenging Reactive Oxygen Species through Inhibiting Nox1.
已发布 PubMed:大蒜提取物中的s-烯丙基-1-半胱氨酸(sac)的分子检测和体外抗氧化活性 Molecular detection and in vitro antioxidant activity of S-allyl-L-cysteine (SAC) extracted from Allium sativum.
已发布 PubMed:大蒜中具有味道活性的美拉德反应产物。 Taste-Active Maillard Reaction Products in Roasted Garlic (Allium sativum).
已发布 PubMed:年龄及其成分对橙花炎症和橙花变性的保护作用。 Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration.
已发布 PubMed:pmk-s005减轻与年龄有关的胃酸分泌 PMK-S005 Alleviates Age-Related Gastric Acid Secretion, 炎 Inflammation, 和大鼠胃中的氧化状态。 and Oxidative Status in the Rat Stomach.
已发布 PubMed:s-烯丙基-1-半胱氨酸衍生物对内质网应激诱导的细胞毒性的橙花保护作用独立于钙蛋白酶抑制。 Neuroprotective effect of S-allyl-l-cysteine derivatives against endoplasmic reticulum stress-induced cytotoxicity is independent of calpain inhibition.
已发布 PubMed:importin-9的下调保护mcf-7细胞免受大蒜衍生的蒜素和紫杉醇联合诱导的凋亡。 Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.
已发布 PubMed:s-烯丙基-1-半胱氨酸在大鼠体内的药代动力学特征是口服吸收高,肾再吸收广泛。 Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption.
已发布 PubMed:在氧化和亚硝化应激的细胞模型中,s-烯丙基-l-半胱氨酸和异寡糖原蛋白可改善线粒体功能 S-allyl-L-cysteine and isoliquiritigenin improve mitochondrial function in cellular models of oxidative and nitrosative stress.
已发布 PubMed:pmk-s005对乙醇诱导的大鼠急性胃损伤的胃保护作用。 Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats.
已发布 PubMed:大蒜中蒜氨酸生物合成中含有黄素的s-加氧单加氧酶的鉴定。 Identification of a flavin-containing S-oxygenating monooxygenase involved in alliin biosynthesis in garlic.
已发布 PubMed:酶法合成γ-1-谷氨酰基-s-烯丙基-1-半胱氨酸 Enzymatic synthesis of γ-L-glutamyl-S-allyl-L-cysteine, 来自大蒜的天然有机硫化合物 a naturally occurring organosulfur compound from garlic, 地衣芽孢杆菌的γ-谷氨酰转肽酶。 by Bacillus licheniformis γ-glutamyltranspeptidase.
已发布 PubMed:通过与大蒜中的活化内源性γ-谷氨酰转肽酶的均相反应有效地生产s-烯丙基-1-半胱氨酸。 Effective production of S-allyl-L-cysteine through a homogeneous reaction with activated endogenous γ-glutamyltranspeptidase in garlic (Allium Sativum).
已发布 PubMed:代谢 Metabolism, excretion, 和狗中s-烯丙基-1-半胱氨酸合成和药代动力学。 and pharmacokinetics of S-allyl-L-cysteine in rats and dogs.
已发布 PubMed:大蒜γ-谷氨酰转肽酶,可催化蒜氨酸生物合成中间体的脱谷氨酰化。 Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin.
已发布 PubMed:大蒜提取物的保护作用 Protective effects of garlic extract, pmk-s005 PMK-S005, 对抗非甾体类抗炎药引起的大鼠急性胃损伤。 against nonsteroidal anti-inflammatory drugs-induced acute gastric damage in rats.
已发布 PubMed:s-烯丙基l-半胱氨酸可保护视网膜免受大鼠的红藻氨酸盐兴奋性毒性。 S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat.
已发布 PubMed: 混合模式反相和阳离子交换液晶显示器 LC-ESI-MS / MS方法开发和验证大鼠血浆中S-烯丙基-1-半胱氨酸 : 在药代动力学研究中的应用。 application to pharmacokinetic studies.
已发布 PubMed:s-烯丙基-1-半胱氨酸对内质网应激诱导的橙花元死亡的保护作用是通过抑制钙蛋白酶介导的。 Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain.
已发布 PubMed:收回。 s-烯丙基-1-半胱氨酸亚砜抑制 脐静脉内皮细胞中肿瘤坏死因子-α诱导的单核细胞粘附和细胞间细胞粘附分子1的表达。 Retraction. S-Allyl-L-cysteine sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells.
已发布 PubMed:和储存时间对腌制过的大蒜中有机硫化合物含量的影响 Effect of processing and storage time on the contents of organosulfur compounds in pickled blanched garlic.
已发布 PubMed:囊对氧化应激的影响,胎盘中无可用蛋白 Effects of SAC on oxidative stress and NO availability in placenta: 对子痫前症的潜在益处。 potential benefits to preeclampsia.
已发布 PubMed:s /烯丙基l-半胱氨酸治疗缺血/再灌注后视网膜的作用及其潜在机制。 The effects and underlying mechanisms of S-allyl l-cysteine treatment of the retina after ischemia/reperfusion.
已发布 PubMed: 来自香叶Adhaerens adhaerens的大蒜素酶及其在产生杀真菌活性中的用途。
已发布 PubMed:The "老龄化 aged 大蒜 Allium sativum L. extract:" (年龄 AGE) and one of its 活性 active ingredients s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine (囊 SAC) as 潜在 potential 预防性的 preventive and 治疗的 therapeutic agents for Alzheimer's 疾病 disease (ad AD).
已发布 PubMed:[s-烯丙基-1-半胱氨酸对离体心脏缺血/再灌注的影响]。 [Effect of S-allyl-L-cysteine on isolate heart subject to ischemia/reperfusion].
已发布 PubMed:烯丙基-1-半胱氨酸对小鼠齿状回细胞增殖和成橙花细胞分化的影响 Effects of s-allyl-L-cysteine on cell proliferation and neuroblast differentiation in the mouse dentate gyrus.
已发布 PubMed:在橙花元培养和app-tg小鼠模型中,通过老化的大蒜提取物和s-烯丙基-1-半胱氨酸治疗,可以防止橙花元和突触的氧化损伤。 Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model.
已发布 PubMed:钯(ii)与s-烯丙基-1-半胱氨酸复合物 Palladium(II) complex with S-allyl-L-cysteine: 新的固态核磁共振 NMR光谱测量 , 分子建模和抗菌测定。 molecular modeling and antibacterial assays.
已发布 PubMed:大蒜黄酮和有机硫化合物 Garlic flavonoids and organosulfur compounds: 对沙奎那韦和达那韦的肝药代动力学的影响。 impact on the hepatic pharmacokinetics of saquinavir and darunavir.
已发布 PubMed:3-(烯丙基硫烷基)-2-氨基丙酸 3-(allyltrisulfanyl)-2-aminopropanoic acid, 大蒜中一种新型的非挥发性水溶性抗菌硫化合物。 a novel nonvolatile water-soluble antimicrobial sulfur compound in heated garlic.
已发布 PubMed:通过衍生化和高效液相色谱-串联质谱(hplc-ms / ms)分析,可以简单地定量测定葡萄酒中超痕量水平的强硫醇。 S-allyl-L-cysteine sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells.
已发布 PubMed:半胱氨酸类似物对急性心肌缺血的保护作用 Protective effects of cysteine analogues on acute myocardial ischemia: 内源性h(2)s生产的新型调节剂。 novel modulators of endogenous H(2)S production.
已发布 PubMed:s-烯丙基l-半胱氨酸可减轻脑缺血引起的海马线粒体功能障碍。 S-allyl L-cysteine diminishes cerebral ischemia-induced mitochondrial dysfunctions in hippocampus.
已发布 PubMed:大鼠肾脏微粒体中含有黄素的单加氧酶同工型3的纯化和表征。 Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes.
已发布 PubMed:脲酶的异常胱氨酸裂解酶活性 Unusual cystine lyase activity of the enzyme alliinase: 直接形成多硫化物。 direct formation of polysulphides.
已发布 PubMed:抗淀粉样变性 Anti-淀粉样蛋白 amyloi狗 dogenic 活动 activity of s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine and its 活动 activity to 破坏稳定 destabilize Alzheimer's β淀粉样蛋白 beta-淀粉样蛋白 amyloid 原纤维 fibrils in 体外 vitro.
已发布 PubMed:淀粉样蛋白β蛋白增强了器官型海马切片培养物中衣霉素诱导的橙花元死亡。 Amyloid beta-protein potentiates tunicamycin-induced neuronal death in organotypic hippocampal slice cultures.
已发布 PubMed:caspase-12在淀粉样β肽诱导的长期培养的有机型海马切片中的毒性中的作用。 Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods.
已发布 PubMed:大蒜的两个结构。 Two structures of alliinase from Alliium sativum L.: 载脂蛋白形式和三元配合物与氨基丙烯酸酯反应中间体共价结合到plp辅因子上。 apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor.
已发布 PubMed:s-烯丙基-1-半胱氨酸通过清除过亚硝酸盐并抑制细胞外信号调节激酶的活性来减轻脑缺血损伤。 S-Allyl-L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase.
已发布 PubMed:葱有机硫化合物的橙花保护和活性氧清除能力的构效关系。 Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds.
已发布 PubMed:饮食中的s-烯丙基-1-半胱氨酸可降低卒中发生率和自发性高血压大鼠的中风发生率,并降低其行为,从而降低死亡率。 Dietary S-allyl-L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats.
已发布 PubMed:大蒜丁香中有机硫化合物的变化 Changes in organosulfur compounds in garlic cloves during storage.
已发布 PubMed:n-乙酰半胱氨酸选择性保护小脑颗粒细胞免受4-羟基壬烯醛诱导的细胞死亡。 N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death.
已发布 PubMed:内质网应激诱导的大鼠海马和小脑颗粒橙花元死亡的比较研究。 Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons.
已发布 PubMed:氧化还原敏感蛋白是大蒜衍生的巯基半胱氨酸衍生物的潜在靶标。 Redox-sensitive proteins are potential targets of garlic-derived mercaptocysteine derivatives.
已发布 PubMed:水溶性大蒜成分与 细胞色素p450的体外相互作用 In vitro interactions of water-soluble garlic components with human cytochromes p450.
已发布 PubMed:熟大蒜提取物及其成分通过多种机制抑制血小板聚集。 Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms.
已发布 PubMed:双(s-烯丙基-1-半胱氨酸)钯(ii)的1h-15n nmr研究。 1H-15N NMR studies of the complex bis(S-allyl-L-cysteinate)palladium(II).
已发布 PubMed:前体系统在洋葱和大蒜中产生蓝色色素的模型研究。 Model studies on precursor system generating blue pigment in onion and garlic.
已发布 PubMed:氨基转移酶 Aminotransferase, 在葱属提取物中发现的涉及l-半胱氨酸s-共轭物的l-氨基酸氧化酶和β-裂合酶反应。与生物活性有关吗? L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity?
已发布 PubMed:一种新方法抑制肿瘤生长 Inhibition of tumor growth by a novel approach: 使用靶向的大蒜素酶递送原位大蒜素生成。 in situ allicin generation using targeted alliinase delivery.
已发布 PubMed:s-烯丙基-l-半胱氨酸选择性保护由淀粉样β蛋白和衣霉素诱导的橙花元死亡培养大鼠海马橙花元。 S-allyl-L-cysteine selectively protects cultured rat hippocampal neurons from amyloid beta-protein- and tunicamycin-induced neuronal death.
已发布 PubMed:淀粉样蛋白β肽和异丁酸在器官型海马培养物中诱导的橙花毒性 Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: s-烯丙基-1-半胱氨酸保护 protection by S-allyl-L-cysteine, 大蒜化合物。 a garlic compound.
已发布 PubMed:s-烯丙基-1-半胱氨酸保护作用 Protective effect of S-allyl-L-cysteine, 大蒜化合物 a garlic compound, 对淀粉样β蛋白诱导的橙花生长因子分化的pc12细胞死亡。 on amyloid beta-protein-induced cell death in nerve growth factor-differentiated PC12 cells.
已发布 PubMed:高效离子对色谱法同时分析蒜氨酸 High-performance ion-pair chromatography method for simultaneous analysis of alliin, deoxyalliin, 使用多重质谱和紫外检测技术检测大蒜产品中的大蒜素和二肽前体。 allicin and dipeptide precursors in garlic products using multiple mass spectrometry and UV detection.
已发布 PubMed:亚砜作为大鼠s-烯丙基-1-半胱氨酸尿代谢产物 Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: 含黄素单加氧酶的证据。 evidence for the involvement of flavin-containing monooxygenases.
已发布 PubMed:通过尿烯丙基巯基尿酸生物监测大蒜的摄入量。 Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid.
已发布 PubMed:nα-(1-脱氧-d-果糖-1-基)-1-精氨酸 N alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, 老化大蒜提取物中鉴定出的抗氧化剂化合物。 an antioxidant compound identified in aged garlic extract.
已发布 PubMed: 和兔肝脏微粒体中蛋氨酸S-氧化 Methionine S-oxidation in human and rabbit liver microsomes: 具有高亲和力的蛋氨酸s-氧化酶活性的证据,不同于含黄素的单加氧酶3。 evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3.
已发布 PubMed:大蒜中含烯丙基的硫化物增加棕色脂肪组织中的解偶联蛋白含量 Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, 和去甲肾上腺素和肾上腺素的分泌。 and noradrenaline and adrenaline secretion in rats.
已发布 PubMed:肝和肾微粒体中含有黄素的单加氧酶形式3的表达的物种和性别差异。 Species and sex differences in expression of flavin-containing monooxygenase form 3 in liver and kidney microsomes.
已发布 PubMed:大蒜素的作用方式 The mode of action of allicin: 捕获自由基并与含硫醇的蛋白质相互作用。 trapping of radicals and interaction with thiol containing proteins.
已发布 PubMed:具有硫代烯丙基的有机硫化合物对培养的大鼠海马橙花元的橙花营养活性。 Neurotrophic activity of organosulfur compounds having a thioallyl group on cultured rat hippocampal neurons.
已发布 PubMed:洋葱蒜氨酸裂解酶的半胱氨酸-s-共轭β-裂解酶活性和吡哆醛磷酸结合位点。 Cysteine-S-conjugate beta-lyase activity and pyridoxal phosphate binding site of onion alliin lyase.
已发布 PubMed:兔肝微粒体和cdna表达的含黄素的单加氧酶对半胱氨酸s-共轭物的氧化 Oxidation of cysteine S-conjugates by rabbit liver microsomes and cDNA-expressed flavin-containing mono-oxygenases: 用s-(1 studies with S-(1,2-二氯乙烯基)-1-半胱氨酸 2-dichlorovinyl)-L-cysteine, s-(1 The acute effects of S-(1,2,2-三氯乙烯基)-1-半胱氨酸 2-trichlorovinyl)-L-cysteine, s-烯丙基-l-半胱氨酸 S-allyl-L-cysteine, 和s-苄基-1-半胱氨酸。 and S-benzyl-L-cysteine.
已发布 PubMed:癌症化学预防的新药物。 New agents for cancer chemoprevention.
已发布 PubMed:志愿者食用大蒜后,n-乙酰基-s-烯丙基-1-半胱氨酸尿排泄量。 Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers.
已发布 PubMed:韭菜中c-s-裂解酶制剂的分离与表征 On the Isolation and Characterization of a C-S-Lyase Preparation from Leek,葱稀饭。 Allium porrum.
已发布 PubMed:一种新颖的氨基酸糖苷和大蒜中的三个氨基酸。 A novel amino acid glycoside and three amino acids from Allium sativum.
已发布 PubMed:洋葱和洋葱之间的种间杂交。 Interspecific hybrid between Allium cepa and Allium sativum.
已发布 PubMed:s-(1 The acute effects of S-(1,2-二氯乙烯基)-1-半胱氨酸及相关化学物质对戊巴比妥麻醉犬的肾功能和超微结构的影响 2-dichlorovinyl)-L-cysteine and related chemicals on renal function and ultrastructure in the pentobarbital-anesthetized dog: 构效关系 structure-activity relationships, 生物转化 biotransformation, 以及独特的针对特定地点的肾毒性。 and unique site-specific nephrotoxicity.
已发布 PubMed:大蒜中s-烷(烯)基-1-半胱氨酸衍生物的hplc,包括定量测定(+)-s-烯丙基-1-半胱氨酸亚砜(alliin)。 HPLC of S-Alk(en)yl-L-cysteine Derivatives in Garlic including Quantitative Determination of (+)-S-Allyl-L-cysteine Sulfoxide (Alliin).
已发布 PubMed:研究大蒜提取物的抗诱变活性。 Studies on the antimutagenic activities of garlic extract.
已发布 PubMed:高等植物的c-s裂解酶 The C-S lyases of higher plants: 大蒜中均一蒜氨酸裂解酶的制备及性质 preparation and properties of homogeneous alliin lyase from garlic (Allium sativum).
已发布 PubMed:烯丙醇生物合成巯基酸 Biosynthesis of mercapturic acids from allyl alcohol, 烯丙基酯和丙烯醛。 allyl esters and acrolein.
已发布 PubMed:大蒜蒜氨酸裂解酶的纯化 Purification of the alliin lyase of garlic, 大蒜 Allium sativum L.
已发布 PubMed:γ-谷氨酰胺-s-烯丙基-l-半胱氨酸 gama-L-Glutamyl-S-allyl-L-cysteine, 大蒜中的一种新的gama-谷氨酰肽。 a new gama-glutamyl peptide in garlic.
 
笔记 Notes:
发生在大蒜中。潜在营养 Occurs in garlic. Potential nutriceutical
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